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    题名 作者 年代 出处 被引量
1Zircon U-Pb Ages of the Granodioritic Porphyry in the Laba Molybdenum Deposit,Yunnan,SW China and Its Geological Implication显示文摘Geza 岛弧是一个著名矿化作用集中区域,在西藏的高原的东方边缘的 Sanjiang 领域的部分。在最近的年里,几迟了的 Yanshanian 花岗石的侵入和联系存款在这个区域被发现了,在桃花源,区域是其一最大 Laba 铝存款。以前的研究建议预定 Laba 矿化作用是 85 ±2 妈。然而, granodioritic 斑岩的年龄仍然保持未知。在这研究,从忍受辉钼矿的 granodioritic 斑岩的三件样品锆石标明日期的 LA-ICP-MS U-Pb 与 85.00 ± 的产生日期一起被进行了0.23 妈(MSWD = 0.58 ) , 85.28 ±0.28 妈(MSWD = 1.12 ) ,并且 84.83 ±0.26 妈(MSWD = 0.79 ) 分别地,显示这些 granodioritic 斑岩在 ∼85 附近在迟了的 Yanshanian 形成了妈。与矿化作用的地质的特征结合了,时间地, Laba 存款遗传上空间地与 granodioritic 斑岩被联系。另外, Laba 存款的年龄与另外的迟了的 Yanshanian 侵入和矿化作用一致,建议矿化作用可能在在迟了的白垩纪期间的 intra 板 extensional 环境下面被产生。YU Haijun LI Wenchang YIN Guanghou LU Yingxiang CAO Xiaomin HUANG Dingzhu DONG Tao ZHANG Youming 2014Acta Geologica Sinica(English Edition)2014,88,4:14
2Phytoremediation of petroleum polluted soil显示文摘An experimental study of the rhizosphere effect on phytoremediation of petroleum polluted soil was carried out with three species of grasses,namely Pannicum,Eleusine indica(L.)Gaerth,and Tall Fescue.After a period of 150 days,this pot experiment showed that the rhizosphere of these three species accelerated the degradation of petroleum hydrocarbons to different extents.The results showed that the number of microorganisms in the rhizosphere increased by three orders of magnitude.The induction of the plant rhizosphere and the coercion influence of petroleum changed the species and activity of microorganisms.The degradation of petroleum hydrocarbons in the rhizosphere was 3-4 times that in unplanted soil.The dehydrogenase activity in the rhizosphere was 1.61-2.20 times that in unplanted soil, but the catalase activity was 0.90-0.93 times that in unplanted soil,and soil moisture content increased by 5%compared with the unplanted soil.Wang Jing Zhang Zhongzhi Su Youming He Wei He Feng Song Hongguang 2008Petroleum Science2008,5,2:12
3Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate显示文摘Jiezhao Zheng Zhujun Li Rui Tian Youming Lu Xiangyu Guo Yong-hui Jiang Xiao-Jiang Li Yong Q Zhang 2017Cell Research2017,27,10:11
4Is tailored therapy based on antibiotic susceptibility effective?A multicenter,open-label,randomized trial显示文摘An effective eradication therapy of Helicobacter pylori(H.pylori)should be used for the first time.In this study,we assessed whether tailored therapy based on antibiotic susceptibility testing is more effective than traditional therapy.We also evaluated the factors that cause treatment failure in high-resistance areas.For this multicenter trial,we recruited 467 H.pylori-positive patients.The patients were randomly assigned to receive tailored triple therapy(TATT),tailored bismuth-containing quadruple therapy(TABQT),or traditional bismuthcontaining quadruple therapy(TRBQT).For the TATT and TABQT groups,antibiotic selection proceeded via susceptibility testing using an agar-dilution test.The patients in the TRBQT group were given amoxicillin,clarithromycin,esomeprazole,and bismuth.Successful eradication was defined as a negative 13C-urea breath test at least eight weeks after the treatment ended.Susceptibility testing was conducted using an agar-dilution test.The eradication rate was examined via intention-to-treat(ITT)and per-protocol(PP)analyses.The clarithromycin,levofloxacin,and metronidazole resistance rates were 26.12%,28.69%,and 96.79%,respectively.Resistance against amoxicillin and furazolidone was rare.The eradication rates for TATT,TRBQT,and TABQT were 67.32%,63.69%,and 85.99%in the ITT analysis(P<0.001)and 74.64%,68.49%,and 91.22%in the PP analysis(P<0.001),respectively.The efficacy of TABQTwas affected by clarithromycin resistance,and bismuth exerted a direct influence on TATT failure.TABQT was the most efficacious regimen for use in high-resistance regions,especially among clarithromycin-susceptible patients.Jie Pan Zhengchao Shi Dingsai Lin Ningmin Yang Fei Meng Lang Lin Zhencheng Jin Qingjie Zhou Jiansheng Wu Jianzhong Zhang Youming Li 2020Frontiers of Medicine2020,14,1:10
5Isolation,purification and characterization of secondary structure of antifreeze protein from Ammopiptanthus mongo-licus显示文摘Antifreeze protein (AFP) from Ammopiptanthus mongolicus leaves was isolated and purified with DEAE cellulose 52, Sephacryl 300, heat treatment and preparative isotachophoresis. The molecular weight of AFP was 50 ku by SDS-PAGE measurement. The average thermal hysteresis activity (THA) of AFP was 0.35℃ at 5 mg/mL using a differential scanning calorimeter (DSC). This AFP showed heated stability. From circular dichroism (CD) of AFP spectral data from 195-240 nm, a well-defined secondary structure of 11% a-helix, 34% antiparallel β-sheet and 55% random coil for the plant AFP was deduced.FEI Yunbiao WEI Lingbo GAO Suqin LU Manchun WANG Baohuai LI Zhifen ZHANG Youming SHU Nianhong JIANG Yong WANG Weixiang 2001Chinese Science Bulletin2001,46,6:8
6First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2].ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma 2020Science China(Physics,Mechanics & Astronomy)2020,63,10:6
7DeST 3.0:A new-generation building performance simulation platform显示文摘Buildings contribute to almost 30%of total energy consumption worldwide.Developing building energy modeling programs is of great significance for lifecycle building performance assessment and optimization.Advances in novel building technologies,the requirements of high-performance computation,and the demands for multi-objective models have brought new challenges for building energy modeling software and platforms.To meet the increasing simulation demands,DeST 3.0,a new-generation building performance simulation platform,was developed and released.The structure of DeST 3.0 incorporates four simulation engines,including building analysis and simulation(BAS)engine,HVAC system engine,combined plant simulation(CPS)engine,and energy system(ES)engine,connected by air loop and water loop balancing iterations.DeST 3.0 offers numerous new simulation features,such as advanced simulation modules for building envelopes,occupant behavior and energy systems,cross-platform and compatible simulation kernel,FMI/FMU-based co-simulation functionalities,and high-performance parallel simulation architecture.DeST 3.0 has been thoroughly evaluated and validated using code verification,inter-program comparison,and case-study calibration.DeST 3.0 has been applied in various aspects throughout the building lifecycle,supporting building design,operation,retrofit analysis,code appliance,technology adaptability evaluation as well as research and education.The new generation building simulation platform DeST 3.0 provides an efficient tool and comprehensive simulation platform for lifecycle building performance analysis and optimization.Da Yan Xin Zhou Jingjing An Xuyuan Kang Fan Bu Youming Chen Yiqun Pan Yan Gao Qunli Zhang Hui Zhou Kuining Qiu Jing Liu Yan Liu Honglian Li Lei Zhang Hong Dong Lixin Sun Song Pan Xiang Zhou Zhe Tian Wenjie Zhang Ruhong Wu Hongsan Sun Yu Huang Xiaohong Su Yongwei Zhang Rui Shen Diankun Chen Guangyuan Wei Yixing Chen Jinqing Peng 2022Building Simulation2022,15,11:5
8Contribution of Microbial Inter-kingdom Balance to Plant Health显示文摘Soil-borne fungal and oomycetal pathogens cause devastating agricultural losses every year. The abundance and diversity of filamentous eukaryotes in the roots of healthy plants are in flue need by root-associated bacteria that protect host plants from disease caused by fungi and oomycetes (Duran et al., 2018).Chunlei Zhang Youming Zhang Zhaojun Ding Yang Bai 2019Molecular Plant2019,12,2:5
9A highly selective dual-channel Hg^(2+) chemosensor based on an easy to prepare double naphthalene Schiff base显示文摘A non-sulfur chemosensor based on an easy to prepare double naphthalene Schiff base is reported for the colorimetric and fluorometric dual-channel sensing of Hg2+ ions by taking advantage of the twisted intramolecular charge transfer (TICT) mechanism. This work provides a novel approach for the selective recognition of mercury ions. Moreover, this sensor serves as a potential recyclable component in sensing materials and the complex L-Hg2+ (L = 1-[(2-naphthalenylimino)methyl]-2-naphthalenol) can therefore be used as a fluorescent sensor for iodine anions. Notably, the color changes are very significant and all the recognition and recycling processes can be observed by the naked eye.ZHANG YouMing SHI BingBing ZHANG Peng HUO JianQiang CHEN Pei LIN Qi LIU Jun WEI TaiBao 2013Science China Chemistry2013,56,5:4
10The hydrogen sulfate recognition properties of azo-salicylaldehyde schiff base receptors显示文摘Azo-salicylaldehyde Schiff base-typed receptors containing an acidic H-bond donor moiety were syn-thesized and characterized. The UV-Vis data indicate that these receptors could act as selective col-orimetric sensors for basic anions and acidic species hydrogen sulfate by different color changes in a water-containing medium. The experiment of Brφnsted acid-base reaction by adding the sodium hy-droxide or perchloric acid revealed that the mechanism of recognition of anions might be deprotona-tion/protonation of the OH fragments by interacting with different anions and that the deprotona-tion/protonation process is fully reversible. The deprotonation/protonation of the receptors is respon-sible for the dramatic color change.WEI TaiBao WANG Jun ZHANG YouMing 2008Science China Chemistry2008,51,11:4
11Novel smart supramolecular metallo-hydrogel that could selectively recognize and effectively remove Pb^(2+) in aqueous solution显示文摘A series of novel and simple ligands based on a biscarboxyl-functionalized benzimidazole derivative were synthesized.The experiments showed that the ligand L2 as a low molecular weight(LMW) hydrogelator could form stable metallo-hydrogels in the presence of up to 0.3 equiv.of lead ions.The metallo-hydrogels were characterized using powder X-ray diffraction,scanning electron microscopy(SEM),and Fourier transform infrared(FT-IR) spectroscopic techniques.When the molar ratio of L2:Pb2+ was in the range of 1:0.3 to 1:0.5 a translucent gel was produced.When the L2:Pb2+ molar ratio was higher than 1:0.5 the resulting gel tended to be opaque.The morphologies of these metallo-hydrogels were L2/Pb ratio dependent,ranging from worm-like to rod-shaped and nanofibrous.The FT-IR and X-ray diffraction(XRD) studies revealed that L2-Pb complexation was the main driving force for the formation of the metallo-hydrogels.In addition,these metallo-hydrogels exhibited outstanding thermostability and thermoreversibility,and displayed a reversible sol-gel transition induced by changes in pH and EDTA concentration.Importantly,ligand L2 showed an excellent capacity for the removal of Pb 2+ in aqueous solution through the formation of metallo-hydrogels.At a L2:Pb molar ratio of 1:0.5 and below,the concentration of residual Pb2+ was as low as 7.6×10-5 mol/L in aqueous solution,and the removal ratio was as high as 95.4%.These results demonstrate that multi-channel responsive smart metallo-hydrogels have the potential to be widely applied in materials science,and might provide the basis for lead pollution capture and removal.WEI TaiBao DANG JianPeng LIN Qi YAO Hong LIU Yong ZHANG WanQiang MING JianJun ZHANG YouMing 2012Science China Chemistry2012,55,12:3
12EAST-Educational Adaptive-optics Solar Telescope显示文摘For the public having a better understanding of solar activities,the Educational Adaptive-optics Solar Telescope(EAST)was built in July 2021 and is located at the Shanghai Astronomy Museum.The EAST consists of a 65 cm aperture solar telescope with a 177-element adaptive optics system and two-channel high resolution imaging system at the Hαand TiO bands,in addition to three full disk solar telescopes at CaK,Hαand TiO bands equipped on the tube of the main telescope.In this paper,the configuration of the EAST is described.Its performance and on-sky observational results are presented.The EAST,to our knowledge,is the most advanced solar telescope for the popularization of science in the world.Due to its excellent performance,the data acquired by the EAST can also be used for research on solar physics and space weather prediction.Changhui Rao Xuejun Rao Zhimao Du Hua Bao Cheng Li Jinlong Huang Youming Guo Libo Zhong Qing Lin Xin Ge Jinsheng Yang Xinlong Fan Yangyi Liu Dan Jia Xin Li Mei Li Ming Zhang Yuntao Cheng Jiahui Zhou Jiawen Yao Lanqiang Zhang Naiting Gu 2022Research in Astronomy and Astrophysics2022,22,6:3
13First light of solar multi-conjugate adaptive optics at the 1-m new vacuum solar telescope显示文摘Observations play a leading role in any branches of astronomy,including solar physics.In order to solve fundamental problems,such as solar dynamo[1],coronal heating[2]and the triggering of major solar eruptions[3],solar observations with spatial resolution better than 0.1 arcsec are required.Such a goal cannot be achieved without the help of adaptive optics(AO),which eliminates the wavefront distortion caused by atmosphere turbulence[4,5].However,solar observations are performed over an extended field ofChangHui Rao LanQiang Zhang Lin Kong YouMing Guo XueJun Rao Hua Bao Lei Zhu LiBo Zhong 2018Science China(Physics,Mechanics & Astronomy)2018,61,8:2
14A Turn-On Fluorescence Chemosensor for Cyanide in Aqueous Media Based on a Nucleophilic Addition Reaction显示文摘Jie Chen Wenting Li Qiao Li Qi Lin Hong Yao Youming Zhang Taibao Wei 2017Chinese Journal of Chemistry2017,35,7:2
15A reversible fluorescent chemosensor for Fe^(3+) and H_2PO_4^- with “on-off-on” switching in aqueous media显示文摘To realize highly selective relay recognition of Fe3+ and H2PO4- ions, a simple benzimidazole-based fluorescent chemosensor(L) was designed and synthesized. Sensor L displays rapid, highly selective, and sensitive recognition to Fe3+ in H2O/DMSO(1:1, v/v) solutions. The in situ-generated L-Fe3+ complex solution exhibits a fast response and high selectivity toward dihydrogen phosphate anion via the Fe3+ displacement approach. The detection limits of sensor L to Fe3+ and L-Fe3+complex to H2PO4- anion were estimated to be 1.0 × 10-9 mol/L. Notably, the sensor was retrievable to indicate dihydrogen phosphate anions with Fe3+, and H2PO4-, in turn, increased. This successive recognition feature of sensor L makes it a potential utility for Fe3+ and H2PO4- anion detection in aqueous media.LIU Jun LIN Qi ZHANG YouMing WEI TaiBao 2014Science China Chemistry2014,57,9:2
16VGLUT3 neurons in median raphe control the efficacy of spatial memory retrieval via ETV4 regulation of VGLUT3 transcription显示文摘The raphe nucleus is critical for feeding, rewarding and memory. However, how the heterogenous raphe neurons are molecularly and structurally organized to engage their divergent functions remains unknown. Here, we genetically target a subset of neurons expressing VGLUT3. VGLUT3 neurons control the efficacy of spatial memory retrieval by synapsing directly with parvalbumin-expressing GABA interneurons(PGIs) in the dentate gyrus. In a mouse model of Alzheimer's disease(AD mice),VGLUT3→PGIs synaptic transmission is impaired by ETV4 inhibition of VGLUT3 transcription. ETV4 binds to a promoter region of VGLUT3 and activates VGLUT3 transcription in VGLUT3 neurons. Strengthening VGLUT3→PGIs synaptic transmission by ETV4 activation of VGLUT3 transcription upscales the efficacy of spatial memory retrieval in AD mice. This study reports a novel circuit and molecular mechanism underlying the efficacy of spatial memory retrieval via ETV4 inhibition of VGLUT3 transcription and hence provides a promising target for therapeutic intervention of the disease progression.Aodi He Chen Zhang Xiao Ke Yao Yi Quntao Yu Tongmei Zhang Hongyan Yu Huiyun Du Hao Li Qing Tian Ling-Qiang Zhu Youming Lu 2022Science China(Life Sciences)2022,65,8:2
17Selective Chemosensor of Fe3+ Based on Fluorescence Quenching by 2,2'-Bisbenzimidazole Derivative in Aqueous Media显示文摘2,2-Bisbenzimidazole 衍生物(L) 是被设计一荧光灯为 Fe3+ 的 chemosensor。简单 chemosensor 显示重要荧光与增加 Fe3+ 的集中熄灭的这在结构上。L 在水的媒介在环境地相关的金属离子之中为 Fe3+ 展出了高选择和 antidisturbance。工作的阴谋的方法显示了在 L 和 Fe3+ 之间复杂的 1:2 的形成,并且系统的可能的有约束力的模式也被建议。另外,进一步的学习证明到 Fe3+ 的传感器的荧光反应上的察觉限制对 107 摩尔敧獬感到不满吗??Taibao Wei Jun Liu Hong Yao Qi Lin Yongqiang Xie Bingbing Shi Peng Zhang Xingmei You Youming Zhang 2013Chinese Journal of Chemistry2013,31,4:2
18Potential therapeutic targets from genetic and epigenetic approaches for asthma显示文摘Asthma is a complex disorder characterised by inflammation of airway and symptoms of wheeze and shortness of breath.Allergic asthma,atopic dermatitis and allergic rhinitis are immunoglobulin E(IgE) related diseases.Current therapies targeting asthma rely on non-specific medication to control airway inflammation and prevent symptoms.Severe asthma remains difficult to treat.Genetic and genomic approaches of asthma and Ig E identified many novel loci underling the disease pathophysiology.Recent epigenetic approaches also revealed the insights of DNA methylation and chromatin modification on histones in asthma and IgE.More than 30 micro RNAs have been identified to have regulating roles in asthma.Understanding the pathways of the novel genetic loci and epigenetic elements in asthma and IgE will provide new therapeutic means for clinical management of the disease in future.Youming Zhang 2016World Journal of Translational Medicine2016,5,1:2
19In-Situ Chemosynthesis of ZnO Nanoparticles to Endow Wood with Antibacterial and UV-Resistance Properties显示文摘Hybrid wood materials have attracted considerable attention because they have combined advantages of both wood and inorganic compounds. This work investigated the microstructural morphology, thermal stability, ultraviolet(UV) stability, and antibacterial property of composites made from wood/ZnO hybrid materials through a facile in-situ chemosynthesis methods. The X-ray diffraction(XRD) and thermogravimetric analysis(TGA) results indicated that the synthesized ZnO particles had an average grain size of about 10.8 nm. The scanning electron microscopy(SEM) observations showed that ZnO nanoflowers self-assembled with nanosheets were presented in wood cell lumens and increased with increasing Zn^(2+)concentrations. ZnO nanoparticles were also generated in the wood cell wall, which was confirmed by the results of energy-dispersive spectroscopy(EDS). The TGA tests also indicated that the thermal stability of wood/ZnO hybrid materials was improved after the formation of ZnO inorganic particles. Finally, the results of antibacterial efficacy tests and UV resistance tests revealed that ZnO nanoparticles showed a promising future as antimicrobial agents against Escherichia coli(E.coli) and UV resistance agents for wood protection.Youming Dong Yutao Yan Huandi Ma Shifeng Zhang Jianzhang Li Changlei Xia Sheldon Q.Shi Liping Cai 2017Journal of Materials Science & Technology2017,33,3:2
20Mechanism of the Effect of Bacillus coagulans on Production Performance of Laying Hens in Late Laying Period显示文摘[Objective]The paper was to investigate the mechanism of Bacillus coagulans preparation in improving production performance of laying hens in late period of laying.[Method]A total of 648 individuals of'Jingfen 1'laying hens(66 weeks of age)in late period of laying were randomly divided into four groups,six replicates each group,and each group had 27 individuals of laying hens.The laying hens in control group were fed with basal diet,and those in experimental groupsⅠ,Ⅱ and Ⅲ were fed with the basal diets added with 3.33×10^6,1×10^7,3.33×10^7 CFU/g B.coagulans,respectively.The pretrial lasted one week,and the formal test lasted eight weeks.[Result]Compared with the control group,the laying rate in group Ⅰ increased significantly,and the feed-gain ratio in experimental group Ⅱ decreased noticeably while the spleen index increased remarkably;the alkaline phosphatase activities and blood calcium content in experimental groups Ⅰ,Ⅱ and Ⅲ increased significantly(P<0.05),while the triglyceride content decreased remarkably(P<0.05);the urea content in experimental groups Ⅰ and Ⅱ decreased obviously(P<0.05).Adding B.coagulans significantly increased the specific activity of amylase,lipase and protease in various intestinal mucosa of small intestine(P<0.05);adding B.coagulans significantly increased the content of follicle-stimulating hormone(FSH)and estradiol(E2),and significantly increased the mRNA expression of follicle stimulating hormone receptor gene(FSHR).[Conclusion]B.coagulans preparation could significantly improve the production performance of laying hens in late period of laying;appropriately enhance the immune capacity of laying hens;improve the serum biochemical indicators;increase the activity of digestive enzymes in the small intestine;and promote the release of gonadal hormone and the mRNA expression of FSHR gene in the ovary.Xing Guanrun Lang Xinrui Wu Ji’an Lou Hongxing Liu Wenqiang Zhang Hengshuo Dong Xinyang Pan Xiaoliang Wang Youming 2019Animal Husbandry and Feed Science2019,11,5:2
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