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| 1 | Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction显示文摘 | Mei Hua Jiang Bing Cai Ying Tuo Jiancheng Wang Zhi Jun Zang Xiang'an Tu Yong Gao Zhijian Su Weiqiang Li Guilan Li Min Zhang Jianwei Jiao Zi Wan Chunhua Deng Bruce T Lahn Andy Peng Xiang | 2014 | Cell Research2014,24,12: | 14 |
| 2 | Overview on the recent study of antimicrobial peptides: Origins, functions, relative mechanisms and application显示文摘 | Yanmei Li Qi Xiang Qihao Zhang Yadong Huang Zhijian Su | 2012 | Peptides2012,,2: | 3 |
| 3 | CD133 + /CD44 + /Oct4 + /Nestin + stem-like cells isolated from Panc-1 cell line may contribute to multi-resistance and metastasis of pancreatic cancer显示文摘 | Dongqing Wang Haitao Zhu Ying Zhu Yanfang Liu Huiling Shen Ruigen Yin Zhijian Zhang Zhaoliang Su | 2012 | Acta Histochemica2012,,: | 1 |
| 4 | 3D thermomechanically coupled FEM analysis of large disk rolling process and trial production显示文摘 | Qinghua Li Zhanchao Ma Taiying Liu Fuguo Li Zhijian Wei Chunmin Su | 2014 | 2014 (1-4)2014,,1: | 1 |
| 5 | Experiments study on the rolling process for heavy disk显示文摘 | Qinghua Li Lianbin Wu Fuguo Li Taiying Liu Shaogang Wang Zhijian Wei Chunming Su | 2013 | The International Journal of Advanced Manufacturing Technology2013,,5: | 1 |
| 6 | Characteristic of liquid metal motion driven by quasi-sinusoidal magnetic fields 显示文摘 | Iwai Kazuhiko Asai Shigeo | 1999 | ISIJ Inter1999,39,12: | 1 |
| 7 | 急性髓系白血病致癌性RNA去甲基酶FTO的小分子靶向干预研究显示文摘文章简介RNA甲基化是高等生物mRNA上最普遍的修饰,参与RNA稳定性、定位、运输、剪切等调控,在基因表达调控中发挥重要作用。2011年FTO被鉴定为m^6A修饰去甲基化酶,开辟了'表观转录'研究新方向。2017年报导急性髓系白血病(AML)高表达FTO导致下游某些mRNA上甲基化丰度降低,引起蛋白水平变化,促进AML形成。然而由于缺乏高质量的小分子工具,FTO是否可以成为抗肿瘤药物的作用靶标有待于深入确证。 | 黄悦 Rui Su Yue Sheng Lei Dong Ze Dong Hongjiao Xu Tengfeng Ni Zijie Scott Zhang Tao Zhang Chenying Li Li Han Zhenyun Zhu Fulin Lian Jiangbo Wei Qiangqiang Deng Yungui Wang Mark Wunderlich Zhiwei Gao Guoyu Pan Dafang Zhong Hu Zhou Naixia Zhang Jianhua Gan Hualiang Jiang James C.Mulloy Zhijian Qian Jianjun Chen 杨财广 | 2020 | 科学新闻2020,,2: | 0 |
| 8 | Fundamental Research and Application Exploration of Optoelectronic Materials and Nanocomposite Materials of Rare Earth显示文摘This project is set in one of the international frontier research fields in inorganic solid chemistry.At present, the research in organic/inorganic hybrid materials and nanocomposite optoelectronic functional materials is under the spotlight in the realm of materials science; there remain quite a few difficulties hiding in the traditional synthesis methods.For instance, the reaction cycle is generally too long, rare earth luminescence components are covalently grafted onto the matrix network, and the stability and luminescence properties are quite poor.Hence, Prof.Zhang and his colleagues proposed a series of new methods and technologies through systematic studies to prepare organic/inorganic hybrid materials and nanocomposite optoelectronic functional materials, striving to solve those kinds of problems.Through many years' efforts, a scientific basis was established by the scientists for the design and performance of the materials, which is recognized of great practical significance. | ZHANG Hongjie WU Zhijian ZHANG Siyuan SU Qiang | 2011 | Bulletin of the Chinese Academy of Sciences2011,25,2: | 0 |
| 9 | OpenSees Three-Dimensional Computational Modeling of Ground-Structure Systems and Liquefaction Scenarios显示文摘The OpenSees computational platform has allowed unprecedented opportunities for conducting seismic nonlinear soil-structure interaction simulations.On the geotechnical side,capabilities such as coupled solid-fluid formulations and nonlinear incrementalplasticity approaches allow for representation of the involved dynamic/seismic responses.This paper presents recent research that facilitated such endeavors in terms of response of ground-foundation-structure systems using advanced material modeling techniques and high-performance computing resources.Representative numerical results are shown for large-scale soil-structure systems,and ground modification liquefaction countermeasures.In addition,graphical user interface enabling tools for routine usage of such 3D simulation environments are presented,as an important element in support of wider adoption and practical applications.In this context,Performance-Based Earthquake Engineering(PBEE)analysis of bridge-ground systems is highlighted as an important topical application. | Zhijian Qiu Jinchi Lu Ahmed Elgamal Lei Su Ning Wang Abdullah Almutairi | 2019 | Computer Modeling in Engineering & Sciences2019,,9: | 0 |
| 10 | Weld Defects in Laser-Welded 7A52 High-Strength Aluminum Alloy Plates with Varying Thicknesses显示文摘This study aims to explore a method suitable for welding 7A52 high-strength aluminum alloy plates with continuously varying thicknesses and the causes of microscopic defects in welds in order to improve welding quality.Comparative tests were conducted to analyze weld defects and deformation when welding the aluminum alloy plates with varying thicknesses at constant laser power.The laser power required for melting welds at varying-thickness positions was estimated.Weld defects and deformation when welding aluminum alloy plates with varying thicknesses at con-tinuous variable laser power were detected.The causes of microscopic weld defects during constant-power welding were analyzed.The welding defects and deformation and the welding quality were improved by welding aluminum alloy plates at continuous variable power. | Dajiang Chen Dabin Zhang Bo Su Zhijian Lai Jijiao Yin An Zhang | 2023 | Journal of Beijing Institute of Technology2023,32,4: | 0 |
| 11 | Mechanical properties and strengthening mechanism of silty sands stabilized with steel slag-based geopolymer binder显示文摘Geopolymer binder has the advantages of early strength,fast solidification,high volume stability,and low permeability.It is beneficial to improve the mechanical performance of silty sands,saving cement consumption and being environmentally friendly.However,the strength improvement of silty sand stabilized with steel slag-based geopolymer was significantly controlled by their material composition and technical parameters.This study conducted a series of unconfined compression tests to investigate the material composition of steel slag-based geopolymer binders and their reasonable mixing ratio for silty sand stabilization.The optimum mixing ratio of precursor(steel slag)to alkaline activator(the combination of Na2SiO3 and CaO)and the optimum dosage of steel slag-based geopolymer for silty sand stabilization were explored.The strengthening mechanism of geopolymer-stabilized silty sands was discussed based on microstructural images and elemental concentrations of primary components observed by SEM and EDS.The results show that when the mass ratio of steel slag:Na2SiO3:CaO was 80:35:21,and the steel slag-based geopolymer material was 15%,the silty sand could achieve the best mechanical performance improvement.The microstructural characteristics of geopolymer-stabilized silty sands at different curing ages illustrated that the compactness and integrity of silty sand structures were enhanced over the curing age.The improving cementitious contact among particles and enlarging particle size was responsible for the strength improvement of silty sand.This research can provide a reference for applying steel slag-based geopolymer in silty sand stabilization in engineering practices. | Shengnian Wang Zewei Chen Zhijian Wu Leilei Gu Jun Su Zexuan Zhao | 2022 | Emergency Management Science and Technology2022,2,1: | 0 |
| 12 | Resilient Event-Triggered Model Predictive Control for Adaptive Cruise Control Under Sensor Attacks显示文摘Dear Editor,This letter addresses the resilient model predictive control(MPC)problems for adaptive cruise control(ACC)systems under sensor attacks.In the light of vulnerabilities of ACC systems to sensor attacks,an intrusion detection mechanism is proposed at the controller side to distinguish abnormal data.Then,the robust control gains are derived to design the terminal region constraint for MPC. | Zhijian Hu Rong Su Kai Zhang Zeyuan Xu Renjie Ma | 2023 | IEEE/CAA Journal of Automatica Sinica2023,10,3: | 0 |
| 13 | RNA m^(6)A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression显示文摘As the most common internal modification of mRNA,Ne-methyladenosine(m^(6)A)and its regulators modulate gene expression and play critical roles in various biological and patholog-ical processes including tumorigenesis.It was reported previously that m^(6)A methyltransferase(writer),methyltransferase-like 3(METTL3)adds m^(6)A in primary microRNAs(pri-miRNAs)and fa-cilitates its processing into precursor miRNAs(pre-miRNAs).However,it is unknown whether m^(6)A modification also plays a role in the maturation process of pre-miRNAs and(if so)whether such a function contributes to tumorigenesis.Here,we found that YTHDF2 is aberrantly overexpressed in acute myeloid leukemia(AML)patients,especially in relapsed patients,and plays an onco-genic role in AML.Moreover,YTHDF2 promotes expression of miR-126-3p(also known as miR-126,as it is the main product of precursor miR-126(pre-miR-126)),a miRNA that was reported as an oncomiRNA in AML,through facilitating the processing of pre-miR-126 into mature miR-126.Mechanistically,YTHDF2 recognizes m^(6)A modification in pre-miR-126 and recruits AGO2,a regulator of pre-miRNA processing,to promote the maturation of pre-miR-126.YTHDF2 posi-tively and negatively correlates with miR-126 and miR-126's downstream target genes,respec-tively,in AML patients,and forced expression of miR-126 could largely rescue YTHDF2/Ythdf2 depletion-mediated suppression on AML cell growth/proliferation and leukemogenesis,indi-cating that miR-126 is a functionally important target of YTHDF2 in AML.Overall,our studies not only reveal a previously unappreciated YTHDF2/miR-126 axis in AML and highlight the ther-apeutic potential of targeting this axis for AML treatment,but also suggest that m^(6)A plays a role in pre-miRNA processing that contributes to tumorigenesis. | Zheng Zhang Keren Zhou Li Han Andrew Small Jianhuang Xue Huilin Huang Hengyou Weng Rui Su Brandon Tan Chao Shen Wei Li Zhicong Zhao Ying Qing Xi Qin Kitty Wang Keith Leung Mark Boldin Chun-Wei Chen David Ann Zhijian Qian Xiaolan Deng Jianjun Chen Zhenhua Chen | 2024 | Genes & Diseases2024,11,1: | 0 |