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| 1 | SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3- TBK1 complex显示文摘SARS coronavirus (SARS-CoV ) 开发躲避干扰素(IFN ) 的抗病毒的活动的对抗机制。以前的研究建议那 SARS-CoV 象 papain 一样朊酶(PLpro ) 禁止 IRF3 小径的激活,它将通常得到柔韧的 IFN 回答,但是机制由 SARS PLpro 使用了禁止 IRF3 小径的激活充分不被知道。在这研究,我们揭开了可以解释 SARS PLpro 怎么高效地禁止 IRF3 小径的激活的新奇机制。我们发现从 SARS-CoV 的抛锚膜的 PLpro 领域(PLpro-TM ) 的那表情禁止类型的 STING/TBK1/IKK-mediated 激活我 IFN 并且破坏 IRF3 的 phosphorylation 和 dimerization,它被圈套和 TBK1 激活。同时,我们证明 PLpro-TM 身体上与 TRAF3, TBK1, IKK,圈套,和 IRF3 交往,为 IFN 的激活装配 STING-TRAF3-TBK1 建筑群的关键部件表示。然而,在在 STING-TRAF3-TBK1 建筑群的部件之间的相互作用被 PLpro-TM 破坏。而且, SARS PLpro-TM 在 STING-TRAF3-TBK1 建筑群减少 RIG-I,圈套, TRAF3, TBK1,和 IRF3 的 ubiquitinated 形式的层次。这些结果一起指向 PLpro 否定地由和 STING-TRAF3-TBK1 建筑群的相互作用通过调整 IRF3 激活的 SARS-CoV 使用的新机制,产出一项 SARS-CoV 反措施对招待天生的免疫。 | Xiaojuan Chen Xingxing Yang Yang Zheng Yudong Yang Yaling Xing Zhongbin Chen | 2014 | Protein & Cell2014，5，5： | 15 |
| 2 | Coronavirus membrane-associated papain-like proteases induce autophagy through interacting with Beclinl to negatively regulate antiviral innate immunity显示文摘 | Xiaojuan Chen Kai Wang Yaling Xing Jian Tu Xingxing Yang Qian Zhao Kui Li Zhongbin Chen | 2014 | Protein & Cell2014，5，12： | 14 |
| 3 | Effect of antisense oligonucleotides targeting telomerase catalytic subunit on tumor cell proliferation in vitro显示文摘To screen specific antitumor drugs targeting telomerase catalytic subunit (hEST2), 12 different hEST2 antisense oligonucleotides were designed based on hEST2 mRNA second structure and transfected into tumor cell lines by the lipofectin-mediated method. Cell growth activity was evaluated by MTT assay. HEST212 was picked out and its specificity, antitumor tree and continuous effect were analyzed. The results showed that hEST212 had promising anti-tumor activity in vitro, hEST2 can be used as a pratical target and an antisense drug candidate for cancer. | Shengqi Wang Li Lin Zhongbin Chen Ruxian Lin Suhong Chen Wei Guan Xiaohong Wang | 2002 | Chinese Science Bulletin2002，47，12： | 10 |
| 4 | Watering techniques and zero-valent iron biochar pH effects on As and Cd concentrations in rice rhizosphere soils,tissues and yield显示文摘Zero-valent iron amended biochar(ZVIB)has been proposed as a promising material in immobilizing heavy metals in paddy fields.In this study,the impacts of p H of ZVIB(p H 6.3 and p H 9.7)and watering management techniques(watering amount in the order of CON(control,5/72)>3/72>1-3/72>3/100>1/72,with 5/72,for example,representing irrigation given to 5 cm above soil surface in 72 hr regular interval)on As and Cd bioavailability for rice and its grain yield(Yield BR)were investigated in a pot experiment.Brown rice As(As BR)content was irrelative to the watering treatments,while significantly decreased(>50%)with the addition of both ZVIB materials.The diminutions of brown rice Cd(Cd BR)content as well as the Yield BR were highly dependent on both the soil amendment materials’p H and watering amount.Among all the watering treatments,3/72 treatment(15%less irrigation water than the CON)with ZVIB 6.3 amendment was the optimum fit for simultaneous reduction of As BR(50%)and Cd BR contents(19%)as well as for significant increment(12%)of the Yield BR.Although high pH(9.7)ZVIB application could also efficiently decrease As and Cd contents in brown rice,it might risk grain yield lost if appropriate(e.g.3/72 in our study)watering management technique was not chosen.Therefore,ZVIB would be an environmentally friendly option as an amendment material with proper selection of watering management technique to utilize As and Cd co-contaminated arable soils safely for paddy cultivation. | Md Shafiqul Islam Yali Chen Liping Weng Jie Ma Zulqarnain Haider Khan Zhongbin Liao Abdoul Salam Issiaka Abdoul Magid Yongtao Li | 2021 | Journal of Environmental Sciences2021，33，2： | 9 |
| 5 | Effect of polymer solution structure on displacement efficiency显示文摘In this paper, a series of experiments, including atomic force microscope (AFM), environmental scanning electron microscope (ESEM), and core displacement tests were conducted to investigate the effect of polymer solution structure on solution properties and oil displacement efficiency. The results show that in the HPAM solution polymer coils were formed and then aggregated into a loose structure, while the HAP2010 solution formed a strong network structure, which would significantly improve the solution viscosity and flow resistance so as to upgrade the capacity of piston-like oil displacement in highly permeable porous media. Meanwhile, the retention of the HAP2010 solution at pore throats were also enhanced, which could reduce water production during subsequent water flooding and enlarge the swept volume during polymer flooding. Therefore, enhancing the interaction among polymer molecules is an effective way to improve the displacement efficiency of polymer solutions in heavy oil reservoirs with high permeability. | Shi Leiting Chen Lei Ye Zhongbin Zhou Wei Zhang Jian Yang Jie Jin Jianbo | 2012 | Petroleum Science2012，9，2： | 9 |
| 6 | PdAg bimetallic electrocatalyst for highly selective reduction of CO2 with low COOH^* formation energy and facile CO desorption显示文摘For electrocatalytic reduction of CO2 to CO,the stabilization of intermediate COOH^* and the desorption of CO^* are two key steps.Pd can easily stabilize COOH^*,whereas the strong CO^* binding to Pd surface results in severe poisoning,thus lowering catalytic activity and stability for CO2 reduction.On Ag surface,CO^* desorbs readily,while COOH^* requires a relatively high formation energy,leading to a high overpotential.In light of the above issues,we successfully designed the PdAg bimetallic catalyst to circumvent the drawbacks of sole Pd and Ag.The PdAg catalyst with Ag-terminated surface not only shows a much lower overpotential(-0.55 V with CO current density of 1 mA/cm^2)than Ag(−0.76 V),but also delivers a CO/H2 ratio 18 times as high as that for Pd at the potential of-0.75 V vs.RHE.The issue of CO poisoning is significantly alleviated on Ag-terminated PdAg surface,with the stability well retained after 4h electrolysis at-0.75 V vs.RHE.Density functional theory(DFT)calculations reveal that the Ag-terminated PdAg surface features a lowered formation energy for COOH^* and weakened adsorption for CO^*,which both contribute to the enhanced performance for CO2 reduction. | Rui Lin Xuelu Ma Weng-Chon Cheong Chao Zhang Wei Zhu Jiajing Pei Kaiyue Zhang Bin Wang Shiyou Liang Yuxi Liu Zhongbin Zhuang Rong Yu Hai Xiao Jun Li Dingsheng Wang Qing Peng Chen Chen Yadong Li | 2019 | Nano Research2019，12，11： | 7 |
| 7 | Atomic Co/Ni dual sites with N/P-coordination as bifunctional oxygen electrocatalyst for rechargeable zinc-air batteries显示文摘Metal-nitrogen-carbon(M-N-C)single-atom catalysts exhibit desirable electrochemical catalytic properties.However,the replacement of N atoms by heteroatoms(B,P,S,etc.)has been regarded as a useful method for regulating the coordination environment.The structure engineered M-N-C sites via doping heteroatoms play an important role to the adsorption and activation of the oxygen intermediate.Herein,we develop an efficient strategy to construct dual atomic site catalysts via the formation of a Co_(1)-PN and Ni1-PN planar configuration.The developed Co_(1)-PNC/Ni1-PNC catalyst exhibits excellent bifunctional electrocatalytic performance in alkaline solution.Both experimental and theoretical results demonstrated that the N/P coordinated Co/Ni sites moderately reduced the binding interaction of oxygen intermediates.The Co_(1)-PNC/Ni1-PNC endows a rechargeable Zn-air battery with excellent power density and cycling stability as an air-cathode,which is superior to that of the benchmark Pt/C+IrO_(2).This work paves an avenue for design of dual single-atomic sites and regulation of the atomic configuration on carbon-based materials to achieve high-performance electrocatalysts. | Botao Hu Aijian Huang Xuejiang Zhang Zheng Chen Renyong Tu Wei Zhu Zhongbin Zhuang Chen Chen Qing Peng Yadong Li | 2021 | Nano Research2021，14，10： | 6 |
| 8 | Quasi-static tensile deformation and fracture behavior of a highly particle-filled composite using digital image correlation method显示文摘Polymer bonded explosives (PBXs) are highly particle-filled composite materials.This paper experimentally studies the tensile deformation and fracture behavior of a PBX simulation by using the semi-circular bending (SCB) test.The deformation and fracture process of a pre-notched SCB sample with a random speckle pattern is recorded by a charge coupled device camera.The displacement and strain fields on the observed surface during the loading process are obtained by using the digital image correlation method.The crack opening displacement is calculated from the displacement fields,the initiation and propagation of the crack are analyzed.In addition,the damage evolution and fracture mechanisms of the SCB sample are analyzed according to the strain fields and the correlation coefficient fields at different loading steps. | Zhongbin Zhou,Pengwan Chen,Baoqiao Guo,Zhuoping Duan,and Fenglei Huang State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology,Beijing 100081,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，5： | 5 |
| 9 | Coprinus comatus-derived nitrogen-containing biocarbon electrocatalyst with the addition of self-generating graphene-like support for superior oxygen reduction reaction显示文摘The development of nitrogen-rich biomassderived carbon catalysts provides an attractive perspective to substitute for Pt-based electrocatalysts for oxygen reduction reaction(ORR). We here report a facile strategy for synthesis of a nitrogen-doped biocarbon/graphene-like composite electrocatalyst by pyrolyzing a solid-state mixture of coprinus comatus biomass and melamine under nitrogen protection. The graphtic carbon nitride formed by polycondensation of melamine at 600 °C acts as a selfsacrificing template to generate the nitrogen-doped graphene-like sheet, which can function as an inserting agent and self-generating support. The composite catalyst exhibits the most promising catalytic activity towards the fourelectron ORR with a half-wave potential of around 0.83 V(vs. RHE), and more excellent stability and tolerance to methanol/ethanol compared to the commercial Pt/C catalyst. It is interestingly found that both a higher content of nitrogen and a larger ratio of graphitic-nitrogen species,which may derive from self-addition of graphene-like support into the catalyst, can effectively improve the electrocatalytic activity. The planar N group may be the nitrogen functionality that is most responsible for maintaining the ORR activity in alkaline medium. This study can largely encourage the exploration of high-performance carbon-based catalysts from economical and sustainable fungus biomass. | Chaozhong Guo Wenli Liao Zhongbin Li Lingtao Sun Haibo Ruan Qingshan Wu Qinghong Luo Jie Huang Changguo Chen | 2016 | Science Bulletin2016，61，12： | 4 |
| 10 | Defective Ni_(3)S_(2)nanowires as highly active electrocatalysts for ethanol oxidative upgrading显示文摘Electrochemical upgrading of biomass ethanol to value-added chemicals is promising for sustainable society.Here,we synthesize defective Ni_(3)S_(2) nanowires(NWs),which show high activity towards electrochemical oxidation of ethanol to acetate.The Ni_(3)S_(2) NWs are formed by the oriented attachment mechanism,and rich defects are introduced during the growth.A low onset potential of 1.31 V and high mass activity of 8,716 mA·mgNi^(-1) at 1.5 V are achieved using the synthesized Ni_(3)S_(2) NWs toward the ethanol electro-oxidation,which are better than the Ni(OH)2 NWs and the Ni_(3)S_(2) nanoparticles(NPs).And the selectivity for the acetate generation is ca.99%.The high activity of Ni_(3)S_(2) NWs is attributed to the easier oxidation of Ni(II)to the catalytically active Ni(III)species with the promotion from S component and rich defects.These results demonstrate that the defective NWs can be synthesized by the oriented attachment method and the defective Ni_(3)S_(2) NWs structure as the efficient nonnoble metal electrocatalysts for oxidative upgrading of ethanol. | Yufeng Zhang Wei Zhu Jinjie Fang Zhiyuan Xu Yanrong Xue Di Liu Rui Sui Qingqing Lv Xuerui Liu Yongsheng Wang Wei Chen Zhongbin Zhuang | 2022 | Nano Research2022，15，4： | 2 |
| 11 | Amorphous M0S2 confined in nitrogen-doped porous carbon for improved electrocatalytic stability toward hydrogen evolution reaction显示文摘Developing non-precious metal catalysts with high activity and stability for electrochemical hydrogen evolution reaction(HER)is of great significance in both scie nee and tech no logy.In this work,N-doped CMK-3,which was prepared with a casting method using SBA-15 as thehard template and ammonia as the nitrogen source,has been utilized to hold MoS2 and restrict its growth to form MoS2@N-CMK-3 composite.As a result,M0S2 was found to have poorly crystallized and the limited space of porous N-CMK-3 made its size much small.Then there are moreactive sites in MoS2.Accordingly,MoS2@N-CMK-3 has exhibited good electrocatalytic performance toward HER in acids with a quite small Tafelslope of 32 mV·dec^-1.And more importantly,compared to MoS2@CMK-3,its stability has been greatly improved,which can be attributedto the interaction between M0S2 and nitrogen atoms avoiding aggregation and mass loss.This work provides an idea that doping a porouscarbon support with nitrogen is an effective way to enhance the stability of the catalyst. | Shaojie Lu Wenjing Wang Shengshuang Yang Wei Chen Zhongbin Zhuang Wenjing Tang Caihong He Jiajing Qian Dekun Ma Yun Yang Shaoming Huang | 2019 | Nano Research2019，12，12： | 2 |
| 12 | Squeeze-Strengthening Effect of Silicone Oil-based Magnetorheological Fluid显示文摘In order to study the squeeze-strengthening effect of silicone oil-based magnetorheological fluid(MRF), theoretical basis of disc squeezing brake was presented and a squeezing braking characteristics test-bed for MRF was designed. Moreover, relevant experiments were carried out and the relationship between squeezing pressure and braking torque was proposed. Experiments results showed that the yield stress of MRF improved linearly with the increasing of external squeezing pressure and the braking torque increased three times when external squeezing pressure achieved 2 MPa. | 刘新华 CHEN Qingqing LIU Hao WANG Zhongbin ZHAO Huadong | 2016 | Journal of Wuhan University of Technology(Materials Science)2016，31，3： | 2 |
| 13 | Photocatalytic hydrogenation of nitroarenes using Cu1.94S-Zn0.23Cd0.77S heteronanorods显示文摘 | Zhanjun Yu Zheng Chen Yueguang Chen Qing Peng Rui Lin Yu Wang Rongan Shen Xing Cao Zhongbin Zhuang Yadong Li | 2018 | Nano Research2018，11，7： | 2 |
| 14 | Continuous dimethyl carbonate synthesis from CO_(2) and methanol over Bi_(x)Ce_(1-x)O_(δ) monoliths:Effect of bismuth doping on population of oxygen vacancies,activity,and reaction pathway显示文摘We evaluated bismuth doped cerium oxide catalysts for the continuous synthesis of dimethyl carbonate(DMC)from methanol and carbon dioxide in the absence of a dehydrating agent.Bi_(x)Ce_(1-x)O_(δ)nanocomposites of various compositions(x=0.06-0.24)were coated on a ceramic honeycomb and their structural and catalytic properties were examined.The incorporation of Bi species into the CeO_(2) lattice facilitated controlling of the surface population of oxygen vacancies,which is shown to play a crucial role in the mechanism of this reaction and is an important parameter for the design of ceria-based catalysts.The DMC production rate of the Bi_(x)Ce_(1-x)O_(δ) catalysts was found to be strongly enhanced with increasing Ov concentration.The concentration of oxygen vacancies exhibited a maximum for Bi_(0.12)Ce_(0.88)O_(δ),which afforded the highest DMC production rate.Long-term tests showed stable activity and selectivity of this catalyst over 45 h on-stream at 140°C and a gas-hourly space velocity of 2,880 mL·g_(cat)^(-1)·h^(-1).In-situ modulation excitation diffuse reflection Fourier transform infrared spectroscopy and first-principle calculations indicate that the DMC synthesis occurs through reaction of a bidentate carbonate intermediate with the activated methoxy(-OCH_(3))species.The activation of C0_(2) to form the bidentate carbonate intermediate on the oxygen vacancy sites is identified as highest energy barrier in the reaction pathway and thus is likely the rate-determining step. | Yongdong Chen Yue Li Wei Chen Wen Wu Xu Zhong-kang Han Ammara Waheed Zhongbin Ye Gao Li Alfons Baiker | 2022 | Nano Research2022，15，2： | 2 |
| 15 | A water - soluble acrylamide hydrophobically associating polymer: synthesis, characterization, and properties as EOR chemical 显示文摘 | Lai Nanjun Dong Wan Ye Zhongbin Dong Jun Qin Xiaoping Chen Weili Chen Ke | 2013 | Journal of Applied Polymer Science2013，129，4： | 1 |
| 16 | Influence of soy protein isolate on the thermal stability of poly(vinyl chloride) in the presence or absence of calcium and zinc stearates显示文摘 | Weifu Dong Xiaokai Ruan Zhongbin Ni Mingqing Chen | 2013 | Polymer Degradation and Stability2013，，： | 1 |
| 17 | Observation of damage evolution in polymer bonded explosives using acoustic emission and digital image correlation显示文摘 | Xian Wang Shaopeng Ma Yingtao Zhao Zhongbin Zhou Pengwan Chen | 2011 | Polymer Testing2011，，8： | 1 |
| 18 | Temperature - induced micelle transition of Gemini surfaetant in aqueous solution 显示文摘 | CHEN HONG YE ZHONGBIN HAN LIJUAN | 2007 | Surface Science2007，601，10： | 1 |
| 19 | Effect of sodium salicylate on the properties of gemini surfactant solutions 显示文摘 | CHEN HONG YE ZHONGBIN HAN LIJUAN | 2010 | J Surfact Deterg2010，13，： | 1 |
| 20 | Stability of Sn-Pb mixed organic–inorganic halide perovskite solar cells:Progress,challenges,and perspectives显示文摘The exploration of low bandgap perovskite material to approach Shockley-Queisser limit of photovoltaic device is of great significance,but it is still challenging.During the past few years,tin–lead(Sn-Pb)mixed perovskites with low bandgaps have been rapidly developed,and their single junction solar cells have reached power conversion efficiency(PCE)over 21%,which also makes them ideal candidate as low bandgap sub-cell for tandem device.Nevertheless,due to the incorporation of unstable Sn^(2+),the stability issue becomes the vital problem for the further development of Sn-Pb mixed perovskite solar cells(PSCs).In this review,we are dedicated to give a full view in current understanding on the stability issue of SnPb mixed perovskites and their PSCs.We begin with the demonstration on the origin of instability of Sn-Pb mixed perovskites,including oxidation of Sn^(2+),defects,and interfacial layer induced instability.Sequentially,the up-to-date developments on the stability improvement of Sn-Pb mixed perovskites and their PSCs is systematically reviewed,including composition engineering,additive engineering,and interfacial engineering.At last,the current challenges and future perspectives on the stability study of Sn-Pb mixed PSCs are discussed,which we hope could promote the further application of Sn-Pb mixed perovskites towards commercialization. | Shaoshen Lv Weiyin Gao Yanghua Liu He Dong Nan Sun Tingting Niu Yingdong Xia Zhongbin Wu Lin Song Chenxin Ran Li Fu Yonghua Chen | 2022 | Journal of Energy Chemistry2022，31，2： | 1 |
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