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| 1 | ZmMs30 Encoding a Novel GDSL Lipase Is Essential for Male Fertility and Valuable for Hybrid Breeding in Maize显示文摘Genic male sterility (GMS) is very useful for hybrid vigor utilization and hybrid seed production. Although a large number of GMS genes have been identified in plants, little is known about the roles of GDSL lipase members in anther and pollen development. Here, we report a maize GMS gene, ZmMs30, which encodes a novel type of GDSL lipase with diverged catalytic residues. Enzyme kinetics and activity assays show that ZmMs30 has lipase activity and prefers to substrates with a short carbon chain. ZmMs30 is specifically expressed in maize anthers during stages 7-9. Loss of ZmMs30 function resulted in defective anther cuticle, irregular foot layer of pollen exine, and complete male sterility. Cytological and lipidomics analyses demonstrate that ZmMs30 is crucial for the aliphatic metabolic pathway required for pollen exine formation and anther cuticle development. Furthermore, we found that male sterility caused by loss of ZmMs30 function was stable in various inbred lines with different genetic background, and that it didn't show any negative effect on maize heterosis and production, suggesting that ZmMs30 is valuable for crossbreeding and hybrid seed production. We then developed a new multi-control sterility system using ZmMs30 and its mutant line, and demonstrated it is feasible for generating desirable GMS lines and valu. able for hybrid maize seed production. Taken together, our study sheds new light on the mechanisms of anther and pollen development, and provides a valuable male-sterility system for hybrid breeding maize. | Xueli An Zhenying Dong Youhui Tian Ke Xie Suowei Wu Taotao Zhu Danfeng Zhang Van Zhou Canfang Niu Biao Ma Quancan Hou Jianxi Bao Simiao Zhang Ziwen Li Yanbo Wang Tingwei Yan Xiaojing Sun Yuwen Zhang Jinping Li Xiangyuan Wan | 2019 | Molecular Plant2019，12，3： | 15 |
| 2 | ^(137)Cs tracing of lacustrine sediments in the Dalian Lake,Qinghai Province,China显示文摘Based upon the analysis of Cs and grain-size parameters, the total amounts of 137Cs deposition by wind and water in the Dalian Lake of Gonghe Basin, Qinghai Province are defined. The vertical profile of 137Cs in the lacustrine sediments exhibits three 137Cs activity maxima and one minimum. The major maximum corresponds to the global I37Cs fallout in 1963; the two secondary maxima correspond to the leakage of the Chernobyl reactor in 1986 and complete desiccation of the lake in 1994, respectively. The minimum corresponds to aeolian deposition caused by extensive reclamation in the late 1980s and early 1990s. The 137Cs data set was used to evaluate average sedimentation rate of the Dalian Lake since 1963. The deposition was stable in 1963-1986 and 1994-1998, and it was rapid during 1986?994. This preliminary study reveals that l37Cs has the same potential to trace environmental changes introduce by human interference in arid/semiarid regions as in humid regions. | VAN Ping, DONG Guangrong & DONG ZhibaoChina Certer of Desert Research at Beijing Normal University, Beijing100875, China:Key Laboratory of Environmental Change and Natural Disaster, the Ministry of Education of China, Beijing Normal University, Beijing 100875, China Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000, China | 2001 | Chinese Science Bulletin2001，46，S1： | 3 |
| 3 | Physiological evaluation of nitrogen use efficiency of different apple cultivars under various nitrogen and water supply conditions显示文摘Nitrogen(N) deficiency is a common problem for apple(Malus×domestica) production in arid regions of China.However,N utilization efficiency(NUE) of different apple cultivars grown under low N conditions in arid regions has not been evaluated.In this study,NUE was assessed for one-year-old seedlings of six apple cultivars,Golden Delicious,Qinguan,Jonagold,Honeycrisp,Fuji and Pink Lady,grafted onto Malus hupehensis Rehd.rootstocks.Four treatments were used,including control water with control N(CWCN),limited water with control N(LWCN),control water with low N(CWLN) and limited water with low N(LWLN).Our results showed that growth indices such as biomass,plant height and stem diameter,and photosynthetic rate of all cultivars decreased in the order CWCN>CWLN>LWCN>LWLN.When subjected to LWLN treatment,Qinguan showed better growth and photosynthetic characters than other tested cultivars.Additionally,Qinguan and Pink Lady had higher NUE,while Honeycrisp and Jonagold had lower NUE,based on the determination of biomass,photosynthetic parameters,chlorophyll content,the maximal photochemical efficiency of PSII(Fv/Fm),15 N and N contents. | WANG Qian LIU Chang-hai HUANG Dong DONG Qing-long LI Peng-min Steve van NOCKER MA Feng-wang | 2020 | Journal of Integrative Agriculture2020，19，3： | 3 |
| 4 | Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome:A multicenter retrospective study显示文摘BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bowel syndrome(IBS).AIM To assess the association of HTR3 polymorphisms with depressive,anxiety,and somatization symptoms in individuals with IBS.METHODS In this retrospective study,623 participants with IBS were recruited from five specialty centers in Germany,Sweden,the United States,the United Kingdom,and Ireland.Depressive,anxiety,and somatization symptoms and sociodemographic characteristics were collected.Four functional SNPs—HTR3A c.-42C>T,HTR3B c.386A>C,HTR3C c.489C>A,and HTR3E c.*76G>A—were genotyped and analyzed using the dominant and recessive models.We also performed separate analyses for sex and IBS subtypes.SNP scores were calculated as the number of minor alleles of the SNPs above.The impact of HTR3C c.489C>A was tested by radioligand-binding and calcium influx assays.RESULTS Depressive and anxiety symptoms significantly worsened with increasing numbers of minor HTR3C c.489C>A alleles in the dominant model(F_(depressive)=7.475,P_(depressive)=0.006;F_(anxiety)=6.535,P_(anxiety)=0.011).A higher SNP score(range 0-6)was linked to a worsened depressive symptoms score(F=7.710,P-linear trend=0.006)in IBS.The potential relevance of the HTR3C SNP was corroborated,showing changes in the expression level of 5-HT3AC variant receptors.CONCLUSION We have provided the first evidence that HTR3C c.489C>A is involved in depressive and anxiety symptoms in individuals with IBS.The SNP score indicated that an increasing number of minor alleles is linked to the worsening of depressive symptoms in IBS. | Sabrina Berens Yuanjun Dong Nikola Fritz Jutta Walstab Mauro D'Amato Tenghao Zheng Verena Wahl Felix Boekstegers Justo Lorenzo Bermejo Cristina Martinez Stefanie Schmitteckert Egbert Clevers Felicitas Engel Annika Gauss Wolfgang Herzog Robin Spiller Miriam Goebel-Stengel Hubert Mönnikes Viola Andresen Frieling Thomas Jutta Keller Christian Pehl Christoph Stein-Thöringer Gerard Clarke Timothy G Dinan Eamonn M Quigley Gregory Sayuk Magnus Simrén Jonas Tesarz Gudrun Rappold Lukas van Oudenhove Rainer Schaefert Beate Niesler | 2022 | World Journal of Gastroenterology2022，28，21： | 2 |
| 5 | Functional Defects in the Fanconi Anemia Pathway in Pancreatic Cancer Cells显示文摘 | Michiel S. Van der Heijden Jonathan R. Brody Eike Gallmeier Steven C. Cunningham David A. Dezentje Dong Shen Ralph H. Hruban Scott E. Kern | 2004 | The American Journal of Pathology2004，，2： | 2 |
| 6 | A critical review of biochar-based nitrogen fertilizers and their effects on crop production and the environment显示文摘Globally,nitrogen(N)fertilizer demand is expected to reach 112 million tonnes to support food production for about 8 billion people.However,more than half of the N fertilizer is lost to the environment with impacts on air,water and soil quality,and biodiversity.Importantly,N loss to the environment contributes to greenhouse gas emissions and climate change.Nevertheless,where N fertilizer application is limited,severe depletion of soil fertility has become a major constraint to sustainable agriculture.To address the issues of low fertilizer N use efficiency(NUE),biochar-based N fertilizers(BBNFs)have been developed to reduce off-site loss and maximize crop N uptake.These products are generally made through physical mixing of biochar and N fertilizer or via coating chemical N fertilizers such as prilled urea with biochar.This review aims to describe the manufacturing processes of BBNFs,and to critically assess the effects of the products on soil properties,crop yield and N loss pathways. | Yurong Gao Zheng Fang Lukas Van Zwieten Nanthi Bolan Da Dong Bert F.Quin Jun Meng Fangbai Li Fengchang Wu Hailong Wang Wenfu Chen | 2022 | Biochar2022，4，1： | 2 |
| 7 | Recent advances on study of hadrosaurid dinosaurs in Heilongjiang(Amur) River area between China and Russia显示文摘Four main dinosaur-bearing sites have been investigated in latest Cretaceous deposits from the Amur/Heilongjiang Region: Jiayin and Wulaga in China (Yuliangze Formation) ,Blagoveschensk and Kundur in Rus- sia (Udurchukan Formation) . More than 90% of the bones discovered in these localities belong to hollowcrested lambeosaurine hadrosaurids: Charonosaurus jiayinensis at Jiayin,Amurosaurus riabinini at Blagoveschensk, Olorotitan arharensis at Kundur,and Sahaliyania elunchunorum at Wulaga. Flat-headed hadrosaurine hadrosau- rids are much less numerous,but appear well diversified as well: Kerberosaurus manakini at Blagoveschensk, Wulagasaurus dongi at Wulaga,and a new genus at Kundur. Theropods are represented by shed teeth and isolated bones; isolated scutes and teeth discovered at Kundur are tentatively attributed to nodosaurids. Palynologi- cal studies suggest that these sites are probably synchronous with the Lancian' vertebrate localities of western North America,which represent the youngest dinosaur faunas in this area. However,the latest Cretaceous dinosaur assemblages are completely different in the Amur/Heilongjiang region (lambeosaurines abundant,ceratopsids absent) and in western North America (ceratopsids abundant,lambeosaurines extremely rare or absent) . This probably reflects some kind of geographical barrier between both areas by Maastrichtian time rather than strong differences in palaeoecological conditions. | Pascal Godefroit Pascaline Lauters Jimmy Van Itterbeeck Yuri L. Bolotsky DONG Zhiming JIN Liyong WU Wenhao Ivan Y. Bolotsky HAI Shulin YU Tingxiang | 2011 | Global Geology2011，14，3： | 2 |
| 8 | Stoichiometric determina- tion of hydroperoxides in oils by Fourier transform near- infrared spectroscopy显示文摘 | DONG J MA K Van De VOORT F R | 1997 | J Assoc Off Anal Chem Ira1997，80，2： | 1 |
| 9 | Influence of various P/NandP/P ligands on the palladium-catalysed reductive carbonylation of nitrobenzene显示文摘 | Wehman P Hans M A van Donge | 1997 | J Organomet Chem1997，535，： | 1 |
| 10 | Factors affecting the extraction of lithium from lepidolite显示文摘 | Van Tri Luong Dong Jun Kang Jeon Woong An Myong Jun Kim Tam Tran | 2013 | Hydrometallurgy2013，，： | 1 |
| 11 | Examining the role of CD1d and natural killer T cells in the development of nephritis in a genetically susceptible lupus model 显示文摘 | Yang JQ Wen X Liu H Folayan G Dong X Zhou M Van Kaer L Singh RR | 2007 | Arthritis Rheum2007，56，4： | 1 |
| 12 | NPR1 modulates crosstalk between salicylate-and jasmonate-dependent defence pathways through a novel function in the cytosol显示文摘 | SPOEL S H KOORNNEEF A CLAESSENS SMC KORZELUS J P VAN PELT J A MUELLER M J BUCHALA A J METRAUX J P BROWN R KAZZAN K VAN LOON L C DONG X N PIETERSE C M J | 2003 | Plant Cell2003，15，： | 1 |
| 13 | Properties of air mass mixing and humidity in the subtropics from measurements of the D/H isotope ratio of water vapor at the Mauna Loa Observatory显示文摘 | Noone David Galewsky Joseph Sharp Zachary D. Worden John Barnes John Baer Doug Bailey Adriana Brown Derek P. Christensen Lance Crosson Eric Dong Feng Hurley John V. Johnson Leah R. Strong Mel Toohey Darin Pelt Aaron Van Wright Jonathon S | 2011 | Journal of Geophysical Research Atmospheres2011，，22： | 1 |
| 14 | Functional characterization of the nuclear localization signal for a suppressor of posttranscriptional gene silencing显示文摘 | Dong X van Wezel R Stanley J | 2003 | J Virol2003，77，12： | 1 |
| 15 | The Digital Belt and Road program in support of regional sustainability显示文摘The Belt and Road initiative has a significant focus on infrastructure,trade,and economic development across a vast region,and it also provides significant opportunities for sustainable development.The combined pressure of climate variability,intensified use of resources,and the fragility of ecosystems make it very challenging,however,to achieve future sustainability.To develop the path in a sustainable way,it is important to have a comprehensive understanding of these issues across nations and evaluate them in a scientific and well-informed approach.In this context,the Digital Belt and Road(DBAR)program was initiated as an international venture to share expertise,knowledge,technologies,and data to demonstrate the role of Earth observation science and technology and big Earth data applications to support large-scale development.In this paper,we identify pressing challenges,present the research priorities and foci of the DBAR program,and propose solutions where big Earth data can make significant contributions.This paper calls for further joint actions and collaboration to build a digital silk road in support of sustainable development at national,regional and global levels. | Huadong Guo Jie Liu Yubao Qiu Massimo Menenti Fang Chen Paul F.Uhlir Li Zhang John van Genderen Dong Liang Ishwaran Natarajan Lanwei Zhu Jiuliang Liu | 2018 | International Journal of Digital Earth2018，11，7： | 1 |
| 16 | Mutation of three cysteine residues in Tomato yellow leaf curl virus-China C2 protein causes dysfunction in pathogenesis and posttranscriptional gene silencing suppression显示文摘 | VAN WEZEL R DONG X LIU H | 2002 | Mol Plant Microbe Interact2002，15，： | 1 |
| 17 | Trimester- and method-specific reference intervalsfor thyroid tests in pregnant Chinese women: methodology, euthyroid definition andiodine status can influence the setting of reference intervals '显示文摘 | Van YQ Dong ZL Dong L | 2011 | Clin Endocrinol (Oxt)2011，74，2： | 1 |
| 18 | DIabetIcperIpheralneuropathytreatmentwIth显示文摘 | Pang GuomIng Yan Yong Zhu Pu XIe Chun guang Nigreen van Guanj Ie Zheng XIao dong TIannat Ionalday Wei AIsheng Zhang Ze quan QIu MIng hIghbosomforest | | 0，，02： | 1 |
| 19 | Automatic diagnosis and controt of distributed solid state lighting systerns显示文摘 | Dong J van Driel W Zhang G | 2011 | Op- tics Express2011，19，7： | 1 |
| 20 | Immunogenieity of venom from four eomman snakes in the South of Vietnam and development of ELISA kit for venom detection 显示文摘 | Van Dong L Quyen le K Eng KH | 2003 | Immunol Methods2003，，： | 1 |
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