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| 1 | Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase显示文摘包含 methyltransferase 建筑群的象 3 一样的 methyltransferase (METTL3 ) 催化 N6-methyladenosine (m6A ) 形成,一个新奇 epitranscriptomic 标记;然而,这建筑群的性质仍然保持大部分未知。这里,我们报导人的 m6A methyltransferase 建筑群, Wilm 的肿瘤 1 伙伴蛋白质(WTAP ) 和象 14 一样的 methyltransferase (METTL14 ) 的二个新部件。WTAP 与 METTL3 和 METTL14 交往,并且为他们的本地化被要求进在 vivo 与处理因素的 pre-mRNA 并且为 m6A methyltransferase 的催化活动充实的原子点缀。RNA 的多数在 vivo 由 WTAP 和 METTL3 跳了代表包含一致 m6A 主题的 mRNAs。当 WTAP 不在时, METTL3 的 RNA 有约束力的能力强烈被减少,建议 WTAP 可以工作调整到 mRNA 目标的 m6A methyltransferase 建筑群的招募。而且,在有 photoactivatable-ribonucleoside-enhanced crosslinking 和 immunoprecipitation (同等片断) 的联合的 transcriptomic 分析说明那 WTAP 和 METTL3 调整涉及抄写并且 RNA 处理的基因拼接的表示和选择。在 zebrafish 胚胎的调停 Morpholino 的击倒的指向 WTAP 或 METTL3 引起了织物区别缺点并且增加了 apoptosis。这些调查结果提供 WTAP 可以在 m6A methyltransferase 建筑群作为一个规章的子单元工作并且在 RNA 的 epitranscriptomic 规定起一个关键作用的充分证据新陈代谢。 | Xiao-Li Ping Bao-Fa Sun Lu Wang Wen Xiao Xin Yang Wen-Jia Wang Samir Adhikari Yue Shi Ying Lv Yu-Sheng Chen Xu Zhao Ang Li Ying Yang Ujwal Dahal Xiao-Min Lou Xi Liu Jun Huang Wei-Ping Yuan Xiao-Fan Zhu Tao Cheng Yong-Liang Zhao Xinquan Wang Jannie M Rendtlew Danielsen Feng Liu Yun-Gui Yang | 2014 | Cell Research2014，24，2： | 244 |
| 2 | TLR4 is essential for dendritic cell activation and anti-tumor T-cell response enhancement by DAMPs released from chemically stressed cancer cells显示文摘免疫疗法和化疗的联合为癌症的某些类型的治疗被认为是一条有希望的途径。然而,内在的机制需要充分被调查为癌症 chemoimmunotherapy 指导更有效的协议的设计。联系危险的分子的模式(阻尼) 能激活有免疫力的房间,是众所周知的,包括树枝状的房间(DC ) ,经由像使用费的受体(TLR ) ;然而,在有免疫力的反应的激活免除化学对待药的肿瘤房间的阻尼的角色需要进一步被阐明。这里,我们发现那 colorectal 与 oxaliplatin (OXA ) 对待的癌症(CRC ) 房间或 5 氟尿嘧啶(5-Fu ) 释放了高活动性的组盒子 1 的高水平(HMGB1 ) 和热吃惊蛋白质 70 (HSP70 ) 。在 OXA/5-Fu 治疗以后,也展出的 CRC 病人的 sera 增加了 HMGB1 和 HSP70 的层次,哪个是著名阻尼。与 OXA/5-Fu 对待的垂死的 CRC 房间的上层清液支持了老鼠和人的 DC 成熟,与 HLA 医生, CD80 和 CD86 表示和 IL-1β 的改进的 upregulation;, TNF-α, MIP-1α, MIP-1β, RANTES 和 IP-10 生产。由 DC 组成的疫苗与导致的化学上强调的 CRC 房间的上层清液搏动了更重要的 IFN-γ在 vitro 并且在 vivo 生产 Th1 反应。然而,化学上强调的 CRC 房间的上层清液没能在 TLR4 缺乏的 DC 导致 phenotypic 成熟和 cytokine 生产,显示在导致阻尼的 DC 成熟和激活的 TLR4 的一个必要角色。而且,有化学上强调的 CRC 房间的上层清液的 pulsing 高效地没导致 IFN-γ在 TLR4 缺乏的 DC 生产 Th1 反应。一起,这些结果证明免除化学上强调的癌症房间的阻尼能经由 TLR4 激活 DC 并且提高反肿瘤 T 房间有免疫力的回答的正式就职,描出一条临床上相关的免疫助手小径由阻尼被触发。 | Hongliang Fang Bing Ang Xinyun Xu Xiaohui Huang Yanfeng Wu Yanping Sun Wenying Wang Nan Li Xuetao Cao Tao Wan | 2014 | Cellular & Molecular Immunology2014，11，2： | 11 |
| 3 | Evaluation of characteristics of left-sided colorectal perfusion in elderly patients by angiography显示文摘BACKGROUND Handling of the inferior mesenteric artery(IMA)and maintaining anastomotic perfusion are important in radical resection of left-sided colorectal cancer.However,the branching of this artery and the drainage patterns of this vein vary among individuals,and the characteristics and perfusion region of this artery in elderly patients remain unclear.AIM To evaluate the characteristics and perfusion region of the IMA in elderly patients using angiography.METHODS We enrolled 154 patients(>65 years old)who underwent digital subtraction angiography of the IMA.The characteristics,bifurcation,and distribution of the IMA and termination of the anastomotic perfusion of the left colon and rectum were examined using digital subtraction angiography.Collateral arterial arches and the IMA hemoperfusion region were also recorded.Perfusion regions were cross-referenced with clinical and anatomical features by the univariate analysis.RESULTS Of 154 patients,25(16.2%)had IMA lesions.The left colic artery arose independently from the IMA in 44.2%of patients,shared a trunk with the sigmoid artery in 35.1%,shared an opening with the sigmoid and superior rectal arteries in 16.9%,and was absent in 5.1%.The IMA perfusion region stopped at the splenic flexure in 50(32.5%)patients.The collateral circulation existed in the colonic perfusion region,including the marginal artery(Drummond’s artery),the ascending branch of the left colonic artery to supply the transverse colon,and the arc of Riolan with a frequency of 100%,22.7%,and 1.9%,respectively.The IMA perfusion region was independently associated with the comorbidity of atherosclerosis,IMA atherosclerotic lesion,branching pattern,collateral circulation,and marginal artery integrity.CONCLUSION The IMA and its branches are prone to arteriosclerosis,and IMA perfusion may be interrupted at the splenic flexure in elderly patients.The applicability and precision of preoperative angiography for evaluating the IMA branching and perfusion patterns could facilitate geriatric laparoscopic left-sided colorectal cancer surgery with suspicion of poor IMA perfusion. | Chao Zhang Ang Li Tao Luo Yu Li Fei Li Jia Li | 2020 | World Journal of Gastroenterology2020，26，24： | 7 |
| 4 | Mechanisms of antiprostate cancer by gum mastic:NF-κB signal as target显示文摘瞄准:学习口香糖乳香的效果,自然树脂,在 proliferationof 上雄激素无关的前列腺癌症 PC-3 房间,并且进一步调查机制 involvedin 这个规章的系统,拿原子因素 kappa B ( NF-kappa B )target.Methods:3-( 4,5-dimethylthiazol-2-yl ) -2,5-diphenyltetrazohum 溴化物( MTT )试金和流动 cytometer wereused 被执行在 PC-3 cells.Then ,记者 geneassay , RT-PCR ,并且西方的弄污的增长上检测口香糖乳香的效果到的信号 Gummastic 禁止了 PC-3 房间生长并且在 cyclin Dl ,关键房间 cycleregulator 和NF-的 PC-3 cells.The 表示在 G1 phase.Gum 乳香 alsosuppressed NF- kappa B 活动堵住了 PC-3 房间周期 kappa B 下游的目标基因,作为 well.Moreover 被减少,口香糖 masticdecreased p-AKT 蛋白质水平并且增加了 I kappaB alpha 蛋白质 level.Conclusion :Gummastic 禁止了增长并且在 PC-3 房间 bysuppressing NF- kappa B 活动和 NF- kappa B 信号堵住了房间周期前进小径。 | Mei-lan HE Ang LI Chun-su XU Shun-li WANG Meng-jie ZHANG Hua GU Yao-qin YANG Hui-hong TAO | 2007 | Acta Pharmacologica Sinica2007，28，3： | 5 |
| 5 | Discovering Overlapping Communities by Clustering Local Link Structures显示文摘Recent advances point out that the existing community detection methods commonly face two challenges:incorrect base-structures and incorrect membership of weak-ties.To overcome both problems,a Local link structure(LLS) clustering based method for overlapping community detection is proposed.We extend the similarity of a pair of links to a group of links named LLS,and thus transform mining LLSs as a pattern mining problem.We prove that LLS with an appropriate threshold can filter weak-ties in the form of bridge and local bridge with its span being larger than 3.A compositive framework is presented for overlapping community detection based on LLS mining and clustering.Comparative experiments on both synthetical and real-world networks demonstrate that our method has advantage over six existing methods on discovering higher quality communities. | TAO Haicheng WANG Youquan WU Zhi'ang BU Zhan CAO Jie | 2017 | Chinese Journal of Electronics2017，26，2： | 3 |
| 6 | Multicenter randomised controlled trial comparing the high definition white light endoscopy and the bright narrow band imaging for colon polyps显示文摘AIM To compare high definition white light endoscopy and bright narrow band imaging for colon polyps' detection rates. METHODS Patients were randomised to high definition white light endoscopy(HD-WLE) or the bright narrow band imaging(b NBI) during withdrawal of the colonoscope. Polyps identified in either mode were characterised using b NBI with dual focus(b NBI-DF) according to the Sano's classification. The primary outcome was to compare adenoma detection rates(ADRs) between the two arms. The secondary outcome was to assess the negative predictive value(NPV) in differentiating adenomas from hyperplastic polyps for diminutive rectosigmoid lesions.RESULTS A total of 1006 patients were randomised to HD-WLE(n = 511) or b NBI(n = 495). The mean of adenoma per patient was 1.62 and 1.84, respectively. The ADRs in b NBI and HD-WLE group were 37.4% and 39.3%, respectively. When adjusted for withdrawal time(OR = 1.19, 95%CI: 1.15-1.24, P < 0.001), the use of b NBI was associated with a reduced ADR(OR = 0.69, 95%CI: 0.52-0.92). Nine hundred and thirty three polyps(86%) in both arms were predicted with high confidence. The sensitivity(Sn), specificity(Sp), positive predictive value and NPV in differentiating adenomatous from non-adenomatous polyps of all sizes were 95.9%, 87.2%, 94.0% and 91.1% respectively. The NPV in differentiating an adenoma from hyperplastic polyp using b NBI-DF for diminutive rectal polyps was 91.0%.CONCLUSION ADRs did not differ between b NBI and HD-WLE, however HD-WLE had higher ADR after adjustment of withdrawal time. b NBI surpassed the PIVI threshold for diminutive polyps. | Rajvinder Singh Kuan Loong Cheong Leonardo Zorron Cheng Tao Pu Dileep Mangira Doreen Siew Ching Koay Carmen Kee Siew Chien Ng Rungsun Rerknimitr Satimai Aniwan Tiing-Leong Ang Khean-Lee Goh Shiaw Hooi Ho James Yun-Wong Lau | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，6： | 2 |
| 7 | Parallel implementation of w-projection wide-field imaging显示文摘w-Projection is a wide-field imaging technique that is widely used in radio synthesis arrays. Processing the wide-field big data generated by the future Square Kilometre Array(SKA) will require significant updates to current methods to significantly reduce the time consumed on data processing. Data loading and gridding are found to be two major time-consuming tasks in w-projection. In this paper, we investigate two parallel methods of accelerating w-projection processing on multiple nodes: the hybrid Message Passing Interface(MPI) and Open Multi-Processing(OpenMP) method based on multicore Central Processing Units(CPUs) and the hybrid MPI and Compute Unified Device Architecture(CUDA)method based on Graphics Processing Units(GPUs). Both methods are successfully employed and operated in various computational environments, confirming their robustness. The experimental results show that the total runtime of both MPI + OpenMP and MPI + CUDA methods is significantly shorter than that of single-thread processing. MPI + CUDA generally shows faster performance when running on multiple nodes than MPI + OpenMP, especially on large numbers of nodes. The single-precision GPU-based processing yields faster computation than the double-precision processing; while the single-and doubleprecision CPU-based processing shows consistent computational performance. The gridding time remarkably increases when the support size of the convolution kernel is larger than 8 and the image size is larger than 2,048 pixels. The present research offers useful guidance for developing SKA imaging pipelines. | Baoqiang Lao Tao An Ang Yu Wenhui Zhang Junyi Wang Quan Guo Shaoguang Guo Xiaocong Wu | 2019 | Science Bulletin2019，64，9： | 2 |
| 8 | Biologically Inspired Design of Context-Aware Smart Products显示文摘The rapid development of information and communication technologies(ICTs)and cyber-physical systems(CPSs)has paved the way for the increasing popularity of smart products.Context-awareness is an important facet of product smartness.Unlike artifacts,various bio-systems are naturally characterized by their extraordinary context-awareness.Biologically inspired design(BID)is one of the most commonly employed design strategies.However,few studies have examined the BID of context-aware smart products to date.This paper presents a structured design framework to support the BID of context-aware smart products.The meaning of context-awareness is defined from the perspective of product design.The framework is developed based on the theoretical foundations of the situated function-behavior-structure ontology.A structured design process is prescribed to leverage various biological inspirations in order to support different conceptual design activities,such as problem formulation,structure reformulation,behavior reformulation,and function reformulation.Some existing design methods and emerging design tools are incorporated into the framework.A case study is presented to showcase how this framework can be followed to redesign a robot vacuum cleaner and make it more context-aware. | Ang Liu Ivan Teo Diandi Chen Stephen Lu Thorsten Wuest Zhinan Zhang Fei Tao | 2019 | Engineering2019，5，4： | 2 |
| 9 | Digital twin-driven complexity management in intelligent manufacturing[version 1;peer review:2 approved]显示文摘Complexity management is one of the most crucial and challenging issues in manufacturing.As an emerging technology,digital twin provides an innovative approach to manage complexity in a more autonomous,analytical and comprehensive manner.This paper proposes an innovative framework of digital twin-driven complexity management in intelligent manufacturing.The framework will cover three sources of manufacturing complexity,including product design,production lines and supply chains.Digital twin provides three services to manage complexity:(1)real-time monitors and data collections;(2)identifications,diagnoses and predictions of manufacturing complexity;(3)fortification of human-machine interaction.A case study of airplane manufacturing is presented to illustrate the proposed framework. | Yuchen Wang Xingzhi Wang Fei Tao Ang Liu | 2021 | Digital Twin2021，1，1： | 2 |
| 10 | Rational integration of defense and repair synergy on PEEK osteoimplants via biomimetic peptide clicking strategy显示文摘Polyetheretherketone(PEEK)has been widely used as orthopedic and dental materials due to excellent mechanical and physicochemical tolerance.However,its biological inertness,poor osteoinduction,and weak antibacterial activity make the clinical applications in a dilemma.Inspired by the mussel adhesion mechanism,here we reported a biomimetic surface strategy for rational integration and optimization of anti-infectivity and osteo-inductivity onto PEEK surfaces using a mussel foot proteins(Mfps)-mimic peptide with clickable azido terminal.The peptide enables mussel-like adhesion on PEEK biomaterial surfaces,leaving azido groups for the further steps of biofunctionalizations.In this study,antimicrobial peptide(AMP)and osteogenic growth peptide(OGP)were bioorthogonally clicked on the azido-modified PEEK biomaterials to obtain a dual-effect of host defense and tissue repair.Since bioorthogonal clicking allows precise collocation between AMP and OGP through changing their feeding molar ratios,an optimal PEEK surface was finally obtained in this research,which could long-term inhibit bacterial growth,stabilize bone homeostasis and facilitate interfacial bone regeneration.In a word,this upgraded mussel surface strategy proposed in this study is promising for the surface bioengineering of inert medical implants,in particular,achieving rational integration of multiple biofunctions to match clinical requirements. | Meng Li Jiaxiang Bai Huaqiang Tao Li Hao Weiling Yin Xiaoxue Ren Ang Gao Ning Li Miao Wang Shiyuan Fang Yaozeng Xu Liang Chen Huilin Yang Huaiyu Wang Guoqing Pan Dechun Geng | 2022 | Bioactive Materials2022，7，2： | 2 |
| 11 | Clinical application of laparoseopic spleneetom y comb ined with perieardial devaseularization显示文摘 | LU FL TAO KX W ANG GB | 2005 | Chin J M in Inv Surg2005，5，1： | 1 |
| 12 | Combating the Coronavirus Pandemic:Early Detection,Medical Treatment,and a Concerted Effort by the Global Community显示文摘The World Health Organization(WHO)has declared the outbreak of 2019 novel coronavirus,known as 2019-nCoV,a pandemic,as the coronavirus has now infected over 2.6 million people globally and caused more than 185,000 fatalities as of April 23,2020.Coronavirus disease 2019(COVID-19)causes a respiratory illness with symptoms such as dry cough,fever,sudden loss of smell,and,in more severe cases,difficulty breathing.To date,there is no specific vaccine or treatment proven effective against this viral disease.Early and accurate diagnosis of COVID-19 is thus critical to curbing its spread and improving health outcomes.Reverse transcription-polymerase chain reaction(RT-PCR)is commonly used to detect the presence of COVID-19.Other techniques,such as recombinase polymerase amplification(RPA),loopmediated isothermal amplification(LAMP),clustered regularly interspaced short palindromic repeats(CRISPR),and microfluidics,have allowed better disease diagnosis.Here,as part of the effort to expand screening capacity,we review advances and challenges in the rapid detection of COVID-19 by targeting nucleic acids,antigens,or antibodies.We also summarize potential treatments and vaccines against COVID-19 and discuss ongoing clinical trials of interventions to reduce viral progression. | Zichao Luo Melgious Jin Yan Ang Siew Yin Chan Zhigao Yi Yi Yiing Goh Shuangqian Yan Jun Tao Kai Liu Xiaosong Li Hongjie Zhang Wei Huang Xiaogang Liu | 2020 | Research2020，，1： | 1 |
| 13 | Dysregulation of PARP1 is involved in development of Barrett's esophagus显示文摘AIM To investigate the potential role of poly(ADP-ribose) polymerase 1(PARP1) in the development of Barrett's esophagus(BE).METHODS A BE mouse model was established to examine the esophageal morphological changes and molecular changes. Microarray analysis was performed to compare the gene expression profiles between BE patients and healthy controls. q PCR was used to examine the PARP1 expression in cell lines after treatment with H_2O_2 and bile acids(p H 4). Immunofluorescence staining, comet assay, and annexin V staining were used to evaluate the impact of PARP1 activity on cell survival and DNA damage response after oxidative stress.RESULTS The gene expression profile in normal and BE esophageal epithelial cells showed that PARP1, the major poly(ADP-ribose) polymerase, was overexpressed in BE. In the mouse model of BE, positive staining for NF-κB, γH2 AX, and poly(ADP-ribose)(PAR) was observed. H_2O_2 and bile acids(p H 4) increased the PARP1 m RNA expression level in normal esophageal epithelial cells. Using sh RNA-PARP1 to suppress PARP1 activity decreased the cell viability after treatment with H_2O_2 and bile acids(p H 4), and increased the oxidative damage as demonstrated by an increase in the levels of H_2O_2 , intracellular reactive oxygen species(ROS), oxidative DNA damage, double-strand breaks, and apoptosis(P < 0.01).CONCLUSION The dysfunction of PARP1 in esophageal epithelial cells increases the levels of ROS and oxidative DNA damage, which could be common risk factors for BE and esophageal adenocarcinoma. | Chao Zhang Teng Ma Tao Luo Ang Li Xiang Gao Zhong-Gao Wang Fei Li | 2018 | World Journal of Gastroenterology2018，24，9： | 1 |
| 14 | Presence of a high-grade component in gastric mucosa-associated lymphoid tissue (MALT) lymphoma is not associated with an adverse prognosis显示文摘 | Mei-Kim Ang Siew Wan Hee Richard Quek Swee Peng Yap Susan Loong Leonard Tan Miriam Tao Soon Thye Lim | 2009 | Annals of Hematology2009，，5： | 1 |
| 15 | Novel mutations in the vWFA2 domain of COCH in two Chinese DF-NA9 families显示文摘 | Yuan HJ Han DY Sun Q Yan D Sun HJ Tao R Cheng J Qin W Angeli S Ouyang XM Yang SZ Feng L Cao JY Feng GY Wang YF Dai P Zhai SQ Yang WY He L Liu XZ | | 0，，： | 1 |
| 16 | Atomic origin of magnetic coupling of antiphase boundaries in magnetite thin films显示文摘Revealing the magnetic coupling nature of boundary defects is crucial for in-depth understanding of the behavior and properties of magnetic materials and devices.Here,magnetite(i.e.,Fe_(3)O_(4))thin films were grown epitaxially on(100)SrTiOsingle-crystal substrates by pulsed laser deposition.Atomic-scale scanning transmission electron microscopy characterizations reveal that three types of antiphase boundaries(APBs)are formed in the Fe_(3)O_(4)thin film.They are the(100)APB that is formed on the(100)plane with a crystal translation of(1/4)a[011^(-)],the typeⅠand typeⅡ(110)APBs that are both formed on the(110)plane with the same crystal translation of(1/4)a[101]but different terminated atomic planes.The typeⅠ(110)APB is terminated at the atomic plane with mixed tetrahedral-and octahedral-sites Fe atoms,the typeⅡ(110)APB is terminated at the octahedral-site Fe plane.First-principles calculations reveal that the(100)APB and the typeⅠ(110)APB tend to form the ferromagnetic coupling that will not decrease the spin polarization of Fe_(3)O_(4)films,while the typeⅡ(110)APB prefers to form the antiferromagnetic coupling that will degrade the magnetic properties.The magnetic coupling modes of the APBs are closely related to the Fe-O-Fe bond angles across the boundaries. | Chunyang Gao Yixiao Jiang Tingting Yao Ang Tao Xuexi Yan Xiang Li Chunlin Chen Xiu-Liang Ma Hengqiang Ye | 2022 | Journal of Materials Science & Technology2022，，12： | 1 |
| 17 | Current status and outlook of biodegradable metals in neuroscience and their potential applications as cerebral vascular stent materials显示文摘Over the past two decades,biodegradable metals(BMs)have emerged as promising materials to fabricate temporary biomedical devices,with the purpose of avoiding potential side effects of permanent implants.In this review,we first surveyed the current status of BMs in neuroscience,and briefly summarized the representative stents for treating vascular stenosis.Then,inspired by the convincing clinical evidence on the in vivo safety of Mg alloys as cardiovascular stents,we analyzed the possibility of producing biodegradable cerebrovascular Mg alloy stents for treating ischemic stroke.For these novel applications,some key factors should also be considered in designing BM brain stents,including the anatomic features of the cerebral vasculature,hemodynamic influences,neuro-cytocompatibility and selection of alloying elements.This work may provide insights into the future design and fabrication of BM neurological devices,especially for brain stents. | Ming Li Miaowen Jiang Yuan Gao Yufeng Zheng Zhi Liu Chen Zhou Tao Huang Xuenan Gu Ang Li Jiancheng Fang Xunming Ji | 2022 | Bioactive Materials2022，7，5： | 0 |
| 18 | Inaugural Editorial - Digital Twin [version 1;peer review: not peer reviewed]显示文摘Professor Fei Tao from Beihang University initiated Digital Twin (ISSN 2752-5783), the first open research publishing platform dedicated to digital twin technologies and applications. It is published by F1000, part of the Taylor & Francis Group and sponsored by Beihang University. Digital Twin has been set up to accommodate the outputs of scientific research and engineering applications that are related to digital twin. | Fei Tao Qinglin Qi Ang Liu | 2021 | Digital Twin2021，1，1： | 0 |
| 19 | Expert consensus on prevention and cardiopulmonary resuscitation for cardiac arrest in COVID-19显示文摘Background:Cardiopulmonary resuscitation(CPR)strategies in COVID-19 patients differ from those in patients suffering from cardiogenic cardiac arrest.During CPR,both healthcare and non-healthcare workers who provide resuscitation are at risk of infection.The Working Group for Expert Consensus on Prevention and Cardiopulmonary Resuscitation for Cardiac Arrest in COVID-19 has developed this Chinese Expert Consensus to guide clinical practice of CPR in COVID-19 patients.Main recommendations:1)A medical team should be assigned to evaluate severe and critical COVID-19 for early monitoring of cardiac-arrest warning signs.2)Psychological counseling and treatment are highly recommended,since sympathetic and vagal abnormalities induced by psychological stress from the COVID-19 pandemic can induce cardiac arrest.3)Healthcare workers should wear personal protective equipment(PPE).4)Mouth-to-mouth ventilation should be avoided on patients suspected of having or diagnosed with COVID-19.5)Hands-only chest compression and mechanical chest compression are recommended.6)Tracheal-intubation procedures should be optimized and tracheal-intubation strategies should be implemented early.7)CPR should be provided for 20-30 min.8)Various factors should be taken into consideration such as the interests of patients and family members,ethics,transmission risks,and laws and regulations governing infectious disease control.Changes in management:The following changes or modifications to CPR strategy in COVID-19 patients are proposed:1)Healthcare workers should wear PPE.2)Hands-only chest compression and mechanical chest compression can be implemented to reduce or avoid the spread of viruses by aerosols.3)Both the benefits to patients and the risk of infection should be considered.4)Hhealthcare workers should be fully aware of and trained in CPR strategies and procedures specifically for patients with COVID-19. | Wei Song Jie Wei Xiangdong Jian Deren Wang Yanhong Ouyang Yuanshui Liu Xianjin Du Ying Chen Yingqi Zhang Heping Xu Shuming Xianyu Qiong Ning Xiang Li Xiaotong Han Feng Zhan Tao Yu Wenteng Chen Jun Zhang Wenwei Cai Sheng’ang Zhou Shengyang Yi Yu Cao Xiaobei Chen Shunjiang Xu Zong’an Liang Duohu Wu Fen Ai Zhong Wang Qingyi Meng Yuhong Mi Sisen Zhang Rongjia Yang Shouchun Yan Wenbin Han Yong Lin Chuanyun Qian Wenwu Zhang Yan Xiong Jun Lv Baochi Liu Yan Cao Xiaojun He Xuelian Sun Yufang Cao Tian’en Zhou | 2021 | Asian Pacific Journal of Tropical Medicine2021，14，6： | 0 |
| 20 | 什么样的爱情让我们真的快乐?显示文摘长期而稳定的情感关系会因为彼此适应而感觉舒适,但你是否正隐藏你的真实感受?——Tracey | Barbara De Angelis Sandy Tao(翻译) Aderwa Huang(翻译) 赵婷(手绘) | 2004 | 米娜(女性大世界)2004，，6： | 0 |
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