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| 1 | Annual cost of illness of stomach and esophageal cancer patientsin urban and rural areas in China: A multi-center study显示文摘Objective: Stomach and esophageal cancer are imposing huge threats to the health of Chinese people whereas there were few studies on the financial burden of the two cancers.Methods: Costs per hospitalization of all patients with stomach or esophageal cancer discharged between September 2015 and August 2016 in seven cities/counties in China were collected, together with their demographic information and clinical details. Former patients in the same hospitals were sampled to collect information on annual direct non-medical cost, indirect costs and annual number of hospitalization. Annual direct medical cost was obtained by multiplying cost per hospitalization by annual number of hospitalization. Annual cost of illness(ACI)was obtained by adding the average value of annual direct medical cost, direct non-medical cost and indirect cost,stratified by sex, age, clinical stage, therapy and pathologic type in urban and rural areas. Costs per hospitalization were itemized into eight parts to calculate the proportion of each part. All costs were converted to 2016 US dollars(1 USD=6.6423 RMB).Results: Totally 19,986 cases were included, predominately male. Mean ages of stomach cancer and urban patients were lower than that of esophageal cancer and rural patients. ACI of stomach and esophageal cancer patients were $10,449 and $13,029 in urban areas, and $2,927 and $3,504 in rural areas, respectively. Greater ACI was associated with male, non-elderly patients as well as those who were in stage I and underwent surgeries.Western medicine fee took the largest proportion of cost per hospitalization.Conclusions: The ACI of stomach and esophageal cancer was tremendous and varied substantially among the population in China. Preferential policies of medical insurance should be designed to tackle with this burden and further reduce the health care inequalities. | Zhixun Yang Hongmei Zeng Ruyi Xia Qian Liu Kexin Sun Rongshou Zheng Siwei Zhang Changfa Xia He Li Shuzheng Liu Zhiyi Zhang Yuqin Liu Guizhou Guo Guohui Song Yigong Zhu Xianghong Wu Bingbing Song Xianzhen Liao Yanfang Chen Wenqiang Wei Guihua Zhuang Wanqing Chen | 2018 | Chinese Journal of Cancer Research2018，30，4： | 22 |
| 2 | Medical expenditures for colorectal cancer diagnosis and treatment: A 10-year high-level-hospital-based multicenter retrospective survey in China, 2002-2011显示文摘Objective: Colorectal cancer(CRC) causes a substantial burden of disease in China and the evidence of economic burden triggered is fundamental for priority setting. The aim of this survey was to quantify medical expenditures and the time trends for CRC diagnosis and treatment in China.Methods: From 2012 to 2014, a hospital-based multicenter retrospective survey was conducted in 13 provinces across China. For each eligible CRC patient diagnosed from 2002 to 2011, clinical information and expenditure data were extracted using a uniform questionnaire. All expenditure data were reported in Chinese Yuan(CNY)using 2011 values.Results: Of the 14,536 CRC patients included, the average age at diagnosis was 58.2 years and 15.8% were stageI cases. The average medical expenditure per patient was estimated at 37,902 CNY [95 % confidence interval(95%CI): 37,282-38,522], and the annual average increase rate was 9.2% from 2002 to 2011(P for trend <0.001), with a cumulative increase of 2.4 times(from 23,275 CNY to 56,010 CNY). The expenditure per patient in stages Ⅰ, Ⅱ, Ⅲ and Ⅳ were 31,698 CNY, 37,067 CNY, 38,918 CNY and 42,614 CNY, respectively(P<0.001). Expenditure significantly differed within various subgroups. Expenses for drugs contributed the largest proportion(52.6%).Conclusions: These conservative estimates illustrated that medical expenditures for CRC diagnosis and treatment in tertiary hospitals in China were substantial and increased rapidly over the 10 years, with drugs continually being the main expense by 2011. Relatively, medical expenditures are lower for CRC in the earlier stages. These findings will facilitate the economic evaluation of CRC prevention and control in China. | Jufang Shi Guoxiang Liu Hong Wang Ayan Mao Chengcheng Liu Lanwei Guo Huiyao Huang Jiansong Ren Xianzhen Liao Yana Bai Xiaojie Sun Xinyu Zhu Jialin Wang Bingbing Song Jinyi Zhou Lin Zhu Haike Lei Yuqin Liu Yunyong Liu Lingbin Du Yutong He Kai Zhang Ni Li Wanqing Chen Min Dai Jie He | 2019 | Chinese Journal of Cancer Research2019，31，5： | 8 |
| 3 | Characterization and corrosion property of nano-rod-like HA on fluoride coating supported on Mg-Zn-Ca alloy×显示文摘The poor corrosion resistance of biodegradable magnesium alloys is the dominant factor that limits theirclinical application. In this study, to deal with this challenge, fluoride coating was prepared on MgeZneCa alloy as the inner coating and then hydroxyapatite (HA) coating as the outer coating was depositedon fluoride coating by pulse reverse current electrodeposition (PRC-HA/MgF2). As a comparative study,the microstructure and corrosion properties of the composite coating with the outer coating fabricatedby traditional constant current electrodeposition (TED-HA/MgF2) were also investigated. Scanningelectron microscopy (SEM) images of the coatings show that the morphology of PRC-HA/MgF2 coating isdense and uniform, and presents nano-rod-like structure. Compared with that of TED-HA/MgF2, thecorrosion current density of Mg alloy coated with PRC-HA/MgF2 coatings decreases from 5.72× 10^-5 A/cm2 to 4.32× 10^-7 A/cm^2, and the corrosion resistance increases by almost two orders of magnitude. Inimmersion tests, samples coated with PRC-HA/MgF2 coating always show the lowest hydrogen evolutionamount, and could induce deposition of the hexagonal structure-apatite on the surface rapidly. Theresults show that the corrosion resistance and the bioactivity of the coatings have been improved byadopting double-pulse current mode in the process of preparing HA on fluoride coating, and the PRC-HA/MgF2 coating is worth of further investigation. | Yashan Feng Shijie Zhu Liguo Wang Lei Chang Bingbing Yan Xiaozhe Song Shaokang Guan | 2017 | Bioactive Materials2017，2，2： | 6 |
| 4 | Reduction of polyethylenimine-coated iron oxide nanoparticles induced autophagy and cytotoxicity by lactosylation显示文摘Superparamagnetic iron oxide(SPIO)nanoparticles are excellent magnetic resonance contrast agents and surface engineering can expand their applications.When covered with amphiphilic alkyl-polyethyleneimine(PEI),the modified SPIO nanoparticles can be used as MRI visible gene/drug delivery carriers and cell tracking probes.However,the positively charged amines of PEI can also cause cytotoxicity and restricts their further applications.In this study,we used lactose to modify amphiphilic low molecular weight polyethylenimine(C_(12-)PEI_(2K))at different lactosylation degree.It was found that the N-alkyl-PEI-lactobionic acid wrapped SPIO nanocomposites show better cell viability without compromising their labelling efficacy as well as MR imaging capability in RAW 264.7 cells,comparing to the unsubstituted ones.Besides,we found the PEI induced cell autophagy can be reduced via lactose modification,indicating the increased cell viability might rely on down-regulating autophagy.Thus,our findings provide a new approach to overcome the toxicity of PEI wrapped SPIO nanocomposites by lactose modification. | Jiuju Du Wencheng Zhu Li Yang Changqiang Wu Bingbing Lin Jun Wu Rongrong Jin Taipeng Shen Hua Ai | 2016 | Regenerative Biomaterials2016，3，4： | 5 |
| 5 | Multifunctional SiC@SiO_(2) Nanofiber Aerogel with Ultrabroadband Electromagnetic Wave Absorption显示文摘Traditional ceramic materials are generally brittle and not flexible with high production costs,which seriously hinders their practical applications.Multifunctional nanofiber ceramic aerogels are highly desirable for applications in extreme environments,however,the integration of multiple functions in their preparation is extremely challenging.To tackle these challenges,we fabricated a multifunctional SiC@SiO_(2) nanofiber aerogel(SiC@SiO_(2) NFA)with a threedimensional(3D)porous cross-linked structure through a simple chemical vapor deposition method and subsequent heat-treatment process.The as-prepared SiC@SiO_(2) NFA exhibits an ultralow density(~11 mg cm^(-3)),ultra-elastic,fatigue-resistant and refractory performance,high temperature thermal stability,thermal insulation properties,and significant strain-dependent piezoresistive sensing behavior.Furthermore,the SiC@SiO_(2) NFA shows a superior electromagnetic wave absorption performance with a minimum refection loss(RL_(min))value of-50.36 d B and a maximum effective absorption bandwidth(EAB_(max))of 8.6 GHz.The successful preparation of this multifunctional aerogel material provides a promising prospect for the design and fabrication of the cutting-edge ceramic materials. | Limeng Song Fan Zhang Yongqiang Chen Li Guan Yanqiu Zhu Mao Chen Hailong Wang Budi Riza Putra Rui Zhang Bingbing Fan | 2022 | Nano-Micro Letters2022，14，9： | 4 |
| 6 | Mahalanobis distance-based fading cubature Kalman filter with augmented mechanism for hypersonic vehicle INS/CNS autonomous integration显示文摘Inertial Navigation System/Celestial Navigation System(INS/CNS)integration,especially for the tightly-coupled mode,provides a promising autonomous tactics for Hypersonic Vehicle(HV)in military demands.However,INS/CNS integration is a challenging research task due to its special characteristics such as strong nonlinearity,non-additive noise and dynamic complexity.This paper presents a novel nonlinear filtering method for INS/CNS integration by adopting the emerging Cubature Kalman Filter(CKF)to handle the strong INS error model nonlinearity caused by HV's high dynamics.It combines the state-augmentation technique into the nonlinear CKF to decrease the negative effect of non-additive noise in inertial measurements.Subsequently,a technique for the detection of dynamic model uncertainty is developed,and the augmented CKF is modified with fading memory to tackle dynamic model uncertainty by rigorously deriving the fading factor via the theory of Mahalanobis distance without artificial empiricism.Simulation results and comparison analysis prove that the proposed method can effectively curb the adverse impacts of non-additive noise and dynamic model uncertainty for inertial measurements,leading to improved performance for HV navigation with tightly-coupled INS/CNS integration. | Bingbing GAO Wenmin LI Gaoge HU Yongmin ZHONG Xinhe ZHU | 2022 | Chinese Journal of Aeronautics2022，35，5： | 4 |
| 7 | (Ca,Sr,Ba)ZrO_(3):A promising entropy-stabilized ceramic for titanium alloys smelting显示文摘A novel entropy-stabilized(ES)(Ca,Sr,Ba)ZrO_(3) ceramic has been designed and synthesized by pressureless sintering of CaZr03,SrZr03 and BaZr03 powders mixtures at 1450℃,1500℃and 1550℃for 3 h.X-ray diffraction,scanning electron microscopy and transmission electron microscopy analyses collectively indicate that a single solid solution is formed with a homogeneous distribution of metal elements after sintering at 1550℃.The relative density and hardness of the ES(Ca,Sr,Ba)ZrO_(3) ceramic sintered at 1550℃are 97.79%and 10.840.33 GPa,re s pectively.This ES(Ca,Sr,Ba)ZrO_(3) exhibits lower thermal conductivity from 373 K to 1073 K than their constituting zirconates,CaZrO_(3),SrZrO_(3) and BaZrO_(3).Most importantly,the ES(Ca,Sr,Ba)ZrO_(3) ceramic possesses good corrosion resistance to TiNi alloy melt and no distinct reaction layer exists between TiNi alloy and ES(Ca,Sr,Ba)ZrO_(3) ceramic in the contact region.The combination of these properties indicates that ES(Ca,Sr,Ba)ZrO_(3) ceramic is promising for use as a novel crucible material for the melting of titanium alloys. | Shuaihang Qiu Mingliang Li Gang Shao Hailong Wang Jinpeng Zhu Wen Liu Bingbing Fan Hongliang Xu Hongxia Lu Yanchun Zhou Rui Zhang | 2021 | Journal of Materials Science & Technology2021，，6： | 3 |
| 8 | Solitary beam propagation in periodic layered Kerr media enables high-efficiency pulse compression and mode self-cleaning显示文摘Generating intense ultrashort pulses with high-quality spatial modes is crucial for ultrafast and strong-field science and can be achieved by nonlinear supercontinuum generation(SCG)and pulse compression.In this work,we propose that the generation of quasi-stationary solitons in periodic layered Kerr media can greatly enhance the nonlinear lightmatter interaction and fundamentally improve the performance of SCG and pulse compression in condensed media.With both experimental and theoretical studies,we successfully identify these solitary modes and reveal their unified condition for stability.Space-time coupling is shown to strongly influence the stability of solitons,leading to variations in the spectral,spatial and temporal profiles of femtosecond pulses.Taking advantage of the unique characteristics of these solitary modes,we first demonstrate single-stage SCG and the compression of femtosecond pulses from 170 to 22 fs with an efficiency>85%.The high spatiotemporal quality of the compressed pulses is further confirmed by highharmonic generation.We also provide evidence of efficient mode self-cleaning,which suggests rich spatiotemporal self-organization of the laser beams in a nonlinear resonator This work offers a route towards highly efficient,simple,stable and highly flexible SCG and pulse compression solutions for state-of-the-art ytterbium laser technology. | Sheng Zhang Zongyuan Fu Bingbing Zhu Guangyu Fan Yudong Chen Shunjia Wang Yaxin Liu Andrius Baltuska Cheng Jin Chuanshan Tian Zhensheng Tao | 2021 | Light(Science & Applications)2021，10，4： | 3 |
| 9 | Additively manufactured metallic biomaterials显示文摘Metal additive manufacturing(AM)has led to an evolution in the design and fabrication of hard tissue substitutes,enabling personalized implants to address each patient’s specific needs.In addition,internal pore architectures integrated within additively manufactured scaffolds,have provided an opportunity to further develop and engineer functional implants for better tissue integration,and long-term durability.In this review,the latest advances in different aspects of the design and manufacturing of additively manufactured metallic biomaterials are highlighted.After introducing metal AM processes,biocompatible metals adapted for integration with AM machines are presented.Then,we elaborate on the tools and approaches undertaken for the design of porous scaffold with engineered internal architecture including,topology optimization techniques,as well as unit cell patterns based on lattice networks,and triply periodic minimal surface.Here,the new possibilities brought by the functionally gradient porous structures to meet the conflicting scaffold design requirements are thoroughly discussed.Subsequently,the design constraints and physical characteristics of the additively manufactured constructs are reviewed in terms of input parameters such as design features and AM processing parameters.We assess the proposed applications of additively manufactured implants for regeneration of different tissue types and the efforts made towards their clinical translation.Finally,we conclude the review with the emerging directions and perspectives for further development of AM in the medical industry. | Elham Davoodi Hossein Montazerian Anooshe Sadat Mirhakimi Masoud Zhianmanesh Osezua Ibhadode Shahriar Imani Shahabad Reza Esmaeilizadeh Einollah Sarikhani Sahar Toorandaz Shima ASarabi Rohollah Nasiri Yangzhi Zhu Javad Kadkhodapour Bingbing Li Ali Khademhosseini Ehsan Toyserkan | 2022 | Bioactive Materials2022，7，9： | 2 |
| 10 | Three-Dimensional Numerical Simulation of Ice Crystal Melting in Jet Engine显示文摘A method was presented for calculating the melting rate of ice crystals in different axial positions in a compressor. The volume of fluid model and enthalpy-porosity model were used to simulate the melting process of single ice crystal. The result was validated by experimental data from literature. The change of the liquid fraction of the ice crystals with the axial position was obtained when the temperature distribution inside the compressor was introduced into the melting process. The liquid fraction of the spherical ice crystals was fitted with the ice crystal diameter as a variable, and the general distribution function for computing liquid fraction in any axial position in the compressor was obtained. The function of axial position as a variable for non-spherical ice crystal was also got. | ZHU Pengfei ZHANG Jiachen HAN Bingbing ZHANG Lifen LIU Zhenxia | 2019 | Journal of Thermal Science2019，28，5： | 2 |
| 11 | A multi-epitope vaccine based on Chlamydia trachomatis major outer membrane protein induces specific immunity in mice显示文摘我们评估了包括主要的外部膜蛋白质(MOMP ) 的一支候选人疫苗的 immunogenicity 和功效 multi-epitopeof Chlamydia trachomatis。从包含多重 T 房间和 B 房间 epitopes 的 MOMP 导出的 multi-epitope 的短基因是人工地,包含 codon 的 synthesized.The recombinant plasmid pET32a (+) 优化了 MOMP multi-epitope 基因被构造。在 Escherichia coli 的 fusionprotein Trx-His-MOMP multi-epitope 的表示被钠 dodecyl sulfatepolyacrylamide 胶化电气泳动和西方的污点分析证实。Balb/c 老鼠是 inoculatedwith 皮下地,三与 2 星期的间隔预定的净化的熔化蛋白质。结果出现了 MOMP multi-epitopeelicited 不仅对 C 的强壮的体液的有免疫力的回答。由显著地产生特定的抗体(IgG1 和 IgG2a ) 的高水平的 trachomatis,而且由 inducingrobust 的细胞的有免疫力的回答在老鼠的细胞毒素的 T 淋巴细胞回答。而且, MOMP multi-epitope 实质地告知 IFN- 的分泌物,表明这支疫苗能导致强壮的 Th1 回答。最后,老鼠与 C 的 MOMP multi-epitope displayeda 减小种牛痘。在 chlamydial 挑战和感染的 C 的一个加速的清理之上流的 trachomatis。trachomatis。在结论, MOMP multi-epitope 疫苗可以对 C 为有效预防 andtherapeutic 疫苗的发展有潜力。trachomatis 感染。 | Jianxin Tu B ailong Hou Bingbing Wang Xiaoyun Lin Wenci Gong Haiyan Dong Shanli Zhu Shao Chen Xiangyang Xue Kong-Nan Zhao Lifang Zhang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，5： | 1 |
| 12 | A Novel Optimal Sen- sitivity Design Scheme for Yarn Tension Sensor Using Surface Acoustic Wave Device显示文摘 | Bingbing Lei Wenke Lua Changchun Zhu | 2014 | Utrasonics2014，，54： | 1 |
| 13 | Signature microRNA Expression Profile of Essential Hypertension and Its Novel Link to Human Cytomegalovirus Infection显示文摘 | Shuqiang Li Jianguo Zhu Weili Zhang Youren Chen Ke Zhang Laurentiu M. Popescu Xinliang Ma Wayne Bond Lau Rong Rong Xueqing Yu Bingbing Wang Yafeng Li Chuanshi Xiao Mingming Zhang Shuyan Wang Liping Yu Alex F. Chen Xinchun Yang Jun Cai | 2011 | Circulation2011，，： | 1 |
| 14 | Recent advances in RNA structurome显示文摘RNA structures are essential to support RNA functions and regulation in various biological processes. Recently, a range of novel technologies have been developed to decode genome-wide RNA structures and novel modes of functionality across a wide range of species. In this review, we summarize key strategies for probing the RNA structurome and discuss the pros and cons of representative technologies. In particular, these new technologies have been applied to dissect the structural landscape of the SARS-CoV-2 RNA genome. We also summarize the functionalities of RNA structures discovered in different regulatory layers-including RNA processing, transport, localization, and mRNA translation-across viruses, bacteria, animals, and plants. We review many versatile RNA structural elements in the context of different physiological and pathological processes(e.g., cell differentiation, stress response, and viral replication). Finally, we discuss future prospects for RNA structural studies to map the RNA structurome at higher resolution and at the single-molecule and single-cell level, and to decipher novel modes of RNA structures and functions for innovative applications. | Bingbing Xu Yanda Zhu Changchang Cao Hao Chen Qiongli Jin Guangnan Li Junfeng Ma Siwy Ling Yang Jieyu Zhao Jianghui Zhu Yiliang Ding Xianyang Fang Yongfeng Jin Chun Kit Kwok Aiming Ren Yue Wan Zhiye Wang Yuanchao Xue Huakun Zhang Qiangfeng Cliff Zhang Yu Zhou | 2022 | Science China(Life Sciences)2022，65，7： | 1 |
| 15 | Microstructure and properties of C f /SiC composites with thin SiCN layer as fiber-protecting coating显示文摘 | Yunzhou Zhu Bingbing Pei Ming Yuan Yan Liu Zhengren Huang | 2013 | Ceramics International2013，，6： | 1 |
| 16 | A loss-of-function mutant allele of a glycosyl hydrolase gene has been co-opted for seed weight control during soybean domestication显示文摘The resultant DNA from loss-of-function mutation can be recruited in biological evolution and development.Here,we present such a rare and potential case of“to gain by loss”as a neomorphic mutation during soybean domestication for increasing seed weight.Using a population derived from a chromosome segment substitution line of Glycine max(SN14)and Glycine soja(ZYD06),a quantitative trait locus(QTL)of 100-seed weight(q HSW)was mapped on chromosome 11,corresponding to a truncatedβ-1,3-glucosidase(βGlu)gene.The novel gene hsw results from a 14-bp deletion,causing a frameshift mutation and a premature stop codon in theβGlu.In contrast to HSW,the hsw completely lostβGlu activity and function but acquired a novel function to promote cell expansion,thus increasing seed weight.Overexpressing hsw instead of HSW produced large soybean seeds,and surprisingly,truncating hsw via gene editing further increased the seed size.We further found that the core 21-aa peptide of hsw and its variants acted as a promoter of seed size.Transcriptomic variation in these transgenic soybean lines substantiated the integration hsw into cell and seed size control.Moreover,the hsw allele underwent selection and expansion during soybean domestication and improvement.Our work cloned a likely domesticated QTL controlling soybean seed weight,revealed a novel genetic variation and mechanism in soybean domestication,and provided new insight into crop domestication and breeding,and plant evolution. | Siming Wei Bin Yong Hongwei Jiang Zhenghong An Yan Wang Bingbing Li Ce Yang Weiwei Zhu Qingshan Chen Chaoying He | 2023 | Journal of Integrative Plant Biology2023，65，11： | 1 |
| 17 | Determination of interface (surface) dilatation rheological properties显示文摘This note establishes a new method that can measure interface dilatation elastic module (ε) and dilatation viscosity (ηd) of all surfactants based on the surface pressure relaxation process. The wide applicability was proved with the stability of foam as an example. | JIANG Long ZHAO Feng TANG Ji’an ZHU Hong LI Jinru LI Bingbing | 2001 | Chinese Science Bulletin2001，46，9： | 1 |
| 18 | DOCK2 regulates antifungal immunity by regulating RAC GTPase activity显示文摘Fungal infections cause~1.5 million deaths each year worldwide,and the mortality rate of disseminated candidiasis currently exceeds that of breast cancer and malaria.The major reasons for the high mortality of candidiasis are the limited number of antifungal drugs and the emergence of drug-resistant species.Therefore,a better understanding of antifungal host defense mechanisms is crucial for the development of effective preventive and therapeutic strategies.Here,we report that DOCK2(dedicator of cytokinesis 2)promotes indispensable antifungal innate immune signaling and proinflammatory gene expression in macrophages.DOCK2-deficient macrophages exhibit decreased RAC GTPase(Rac family small GTPase)activation and ROS(reactive oxygen species)production,which in turn attenuates the killing of intracellular fungi and the activation of downstream signaling pathways.Mechanistically,after fungal stimulation,activated SYK(spleen-associated tyrosine kinase)phosphorylates DOCK2 at tyrosine 985 and 1405,which promotes the recruitment and activation of RAC GTPases and then increases ROS production and downstream signaling activation.Importantly,nanoparticle-mediated delivery of in vitro transcribed(IVT)Rac1 mRNA promotes the activity of Rac1 and helps to eliminate fungal infection in vivo.Taken together,this study not only identifies a critical role of DOCK2 in antifungal immunity via regulation of RAC GTPase activity but also provides proof of concept for the treatment of invasive fungal infections by using IVT mRNA. | Xiaojian Ma Xi Tan Bingbing Yu Wanwei Sun Heping Wang Huijun Hu Yanyun Du Ruirui He Ru Gao Qianwen Peng Zhihui Cui Ting Pan Xiong Feng Junhan Wang Chengqi Xu Bin Zhu Wei Liu Chenhui Wang | 2022 | Cellular & Molecular Immunology2022，19，5： | 1 |
| 19 | Complete oxida- tion of formaldehyde at ambient temperature overT-Al203 sup- ported Au eatalyst显示文摘 | Chen Bingbing Shi Chuan Zhu Xiaobing | 2013 | Catalysis Communications2013，，42： | 1 |
| 20 | Visualizing Material Processing via Photoexcitation-ControlledOrganic-Phase Aggregation-Induced Emission显示文摘Aggregation-induced emission(AIE)has been much employed for visualizing material aggregation and self-assembly.However,water is generally required for the preparation of the AIE aggregates,the operation of which limits numerous material processing behaviors.Employing hexathiobenzene-based small molecules,monopolymers,and block copolymers as different material prototypes,we herein achieve AIE in pure organic phases by applying a nonequilibrium strategy,photoexcitationcontrolled aggregation.This strategy enabled a dynamic change of molecular conformation rather than chemical structure upon irradiation,leading to a continuous aggregation-dependent luminescent enhancement(up to~200-fold increase of the luminescent quantum yield)in organic solvents.Accompanied by the materialization of the nonequilibrium strategy,photoconvertible self-assemblies with a steady-state characteristic can be achieved upon organic solvent processing.The visual monitoring with the luminescence change covered the whole solution-to-film transition,as well as the in situ photoprocessing of the solid-state materials. | Jian Gu Bingbing Yue Glib V.Baryshnikov Zhongyu Li Man Zhang Shen Shen HansÅgren Liangliang Zhu | 2021 | Research2021，，1： | 1 |
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