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| 1 | New eolian red clay sequence on the western Chinese Loess Plateau linked to onset of Asian desertification about 25 Ma ago显示文摘The expansion of inland Asia deserts has considerably influenced the environmental, social and economic activities in Asia. Aridification of inland Asia, especially timing of the initiation of Asian desertification, is a contentious topic in paleoclimatology. Late Cenozoic eolian loess-red clay sequences on the Chinese Loess Plateau, which possess abundant paleoclimatic and paleo-environmental information, can be regarded as an indicator of inland Asia desertification. Here we present a detailed magnetostratigraphic investigation of a new red clay sequence about 654 m in Zhuanglang located at the western Chinese Loess Plateau. Sedimentological, geochemical, mineralogical, and quartz morphological lines of evidence show that the red clay is of eolian origin. Magnetostratigraphic correlations indicate that this core sequence spans from 25.6 to 4.8 Ma, and typical eolian red clay appears as early as 25 Ma. This extends the lower limit of the red clay on the Chinese Loess Plateau from the previously thought early Miocene back into the late Oligocene. This new red clay record further implies that the inland Asia desertification was initiated at least by the late Oligocene. This sequence provides a unique high-resolution geological record for understanding the inland Asia desertification process since the late Oligocene. | QIANG XiaoKe AN ZhiSheng SONG YouGui CHANG Hong SUN YouBin LIU WeiGuo AO Hong DONG JiBao FU ChaoFeng WU Feng LU FengYan CAI YanJun ZHOU WeiJian CAO JunJi XU XinWen AI Li | 2011 | Science China Earth Sciences2011，54，1： | 73 |
| 2 | Evolution of planetary boundary layer under different weather conditions,and its impact on aerosol concentrations显示文摘一个领域实验在天津被进行,从 2010 年 9 月 930 日的中国,在表面空气污染物质上集中了于行星的边界层(PBL ) 和它的影响的进化。实验使用了三台遥感仪器,风侧面雷达( WPR ),微波辐射计( MWR )和微脉搏的激光雷达( MPL ),到检测风,温度,和喷雾器 backscattering 系数并且到的垂直侧面测量表面污染物质的垂直侧面(喷雾器,公司, SO2 , NOx ),并且也从 255-m 收集了声音的风速表数据气象学的塔。把大小基于这些, PBL 的进化被估计。平均 PBL 高度在夜间期间在 noon/afternoon-time,和 200300 m 期间是大约 10001300 m。PBL 高度和喷雾器集中是相关反的在期间清楚并且薄雾条件。当平均喷雾器集中分别地是在薄雾和晴朗天空条件下面的 52 和 17 g/m3 时,平均最大的 PBL 高度是 1.08 和 1.70 km。太阳的放射上的喷雾器和云的影响基于从 255-m 收集的声音的风速表数据被观察气象学的塔。当 PBL 的镇压结构进一步削弱了污染物质的散开时,热流动被发现被薄雾(重污染) 或云显著地减少了,它趋于压抑 PBL 的发展,导致重污染。这个可能的积极反馈周期(更多的喷雾器降低 PBL 高度更多的喷雾器) 将在大城市为重地面污染导致一个加速过程。 | Jiannong Quan Yang Gao Qiang Zhang Xuexi Tie Junji Cao Suqin Han Junwang Meng Pengfei Chen Delong Zhao | 2013 | Particuology2013，11，1： | 51 |
| 3 | The Tartary Buckwheat Genome Provides Insights into Rutin Biosynthesis and Abiotic Stress Tolerance显示文摘 | Zhang, Lijun Li, Xiuxiu Ma, Bin Gao, Qiang Du, Huilong Han, Yuanhuai Li, Yan Cao, Yinghao Qi, Ming Zhu, Yaxin Lu, Hongwei Ma, Mingchuan Liu, Longlong Zhou, Jianping Nan, Chenghu Qin, Yongjun Wang, Jun Cui, Lin Liu, Huimin Liang, Chengzhi Qiao, Zhijun | 2017 | Molecular Plant2017，10，9： | 53 |
| 4 | Effects of penehyclidine hydrochloride on rat intestinal barrier function during cardiopulmonary bypass显示文摘AIM:To test the ability of penehyclidine hydrochloride (PHC) to attenuate intestinal injury in a rat cardiopulmonary bypass (CPB) model.METHODS:Male Sprague-Dawley rats were randomly divided into six groups (eight each):sham-operated control;sham-operated low-dose PHC control (0.6 mg/kg);sham-operated high-dose PHC control (2.0 mg/kg);CPB vehicle control;CPB low-dose PHC (0.6 mg/kg);and CPB high-dose PHC (2.0 mg/kg).Blood samples were collected from the femoral artery 2 h after CPB for determination of plasma diamine oxidase (DAO),D-lactate and endotoxin levels.Spleen,liver,mesenteric lymph nodes and lung were removed for biochemical analyses.Intestinal tissue ultrastructure was examined by electron microscopy.RESULTS:In the sham-operated groups,high-and low-dose-PHC had no significant impact on the levels of DAO,D-lactate and endotoxin,or the incidence of intestinal bacterial translocation (BT).Serum levels of DAO,D-lactate,endotoxin and the incidence of intestinal BT were significantly increased in the surgical groups,compared with the sham-operated groups (0.543 ± 0.061,5.697 ± 0.272,14.75 ± 2.46,and 0/40 vs 1.038 ± 0.252,9.377 ± 0.769,60.37 ± 5.63,and 30/40,respectively,all P < 0.05).PHC alleviated the biochemical and histopathological changes in a dosedependent manner.Serum levels of DAO,D-lactate,and endotoxin and the incidence of intestinal BT in the high-dose PHC group were significantly lower than in the low-dose PHC group (0.637 ± 0.064,6.972 ± 0.349,29.64 ± 5.49,and 14/40 vs 0.998 ± 0.062,7.835 ± 0.330,38.56 ± 4.28,and 6/40,respectively,all P < 0.05).CONCLUSION:PHC protects the structure and function of the intestinal mucosa from injury after CPB in rats. | Ying-Jie Sun Hui-Juan Cao Qiang Jin Yu-Gang Diao Tie-Zheng Zhang | 2011 | World Journal of Gastroenterology2011，17，16： | 35 |
| 5 | Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice显示文摘最近的研究开始在心脏的肥大和机能障碍的致病揭示了 microRNAs (miRNAs ) 的关键角色。在这研究,我们测试了是否转变生长 factor-β(TGF-β) 调整 miRNA 在心脏的肥大和心失败(HF ) 的发展起了一个枢轴的作用。我们观察到 miR-27b 是在 cardiomyocyte 特定的 Smad4 猛烈老鼠的心的 upregulated,它开发了心脏的肥大。在 vitro,实验证明 miR-27b 表示能被 TGF-β 禁止; 1 并且它的 overexpression 支持了 hypertrophic 房间生长,当 miR-27b 抑制导致了 hypertrophic 房间的抑制时,生长由 phenylephrine (PE ) 引起了处理。而且,有 miR-27b 的 cardiomyocyte 特定的 overexpression 的转基因的老鼠的分析表明 miR-27b overexpression 是足够的导致心脏的肥大和机能障碍。我们验证了 peroxisome 激活 proliferator 的 receptor-γ(PPAR-γ) 作为在 cardiomyocyte 的 miR-27b 的一个直接目标。一致地, miR-27b 转基因的老鼠显著地显示了 PPAR-γ 的底层;比控制鼠标。而且,在用在一只 pressure-overload-induced 老鼠的特定的 antagomir 的 miR-27b 的 vivo silencing, HF 的模型增加了心脏的 PPAR-γ表示,稀释心脏的肥大和机能障碍。我们的学习的结果表明那 TGF-β 1-regulated miR-27b 涉及心脏的肥大的规定,并且为心脏病作为一个有效治疗学的目标验证 miR-27b。 | Jian Wang Yao Song Yan Zhang Han Xiao Qiang Sun Ning Hou Shuilong Guo Youliang Wang Kaiji Fan Dawei Zhan Lagabaiyila Zha Yang Cao Zhenhua Li Xuan Cheng Youyi Zhang Xiao Yang | 2012 | Cell Research2012，22，3： | 36 |
| 6 | Selection of Parents for Breeding Edible Varieties of Sweetpotato with High Carotene Content显示文摘Sweetpotato varieties with high carotene content have high value for human health. This work aims to improve the breeding efficiency of special varieties with high carotene content by combining molecular markers and agronomic traits to evaluate and screen the parents. The cluster analysis was carried out to identify and screen promising parents by utilizing phenotypic results of the agronomic and characteristic traits, and RAPD and ISSR markers of 15 parents and their offspring by group crossing. Among different parental materials, greater variations were observed in two important traits, the carotene content and the storage root yield. Negative correlation was found between the carotene content and both fresh and dried root yields. The most significant positive correlation was between the carotene content of parents and that of their offspring, with the coefficient of correlation value of 0.7932**. The relationship based on the agronomic characters of the trial materials was not in agreement with the known genealogy, while that based on the molecular marker data showed better result. Each primer amplified 13.8 bands of ISSR markers on average, in which the rate of polymorphic loci was 89.6%. 9.4 bands of RAPD markers were amplified per primer, in which the rate of polymorphic bands was 74.46%. Large genetic variation of carotene content was found among the parents. For analyzing the genetic diversity of sweetpotato, the molecular marker methods were better than morphological traits; ISSR markers were more efficient than RAPD markers. The combination of molecular markers and agronomic trait analysis may provide valuable theoretic basis for selection of parents to breed new varieties with high carotene content. | MA Dai-fu LI Qiang LI Xiu-ying LI Hong-min TANG Zhong-hou HU Ling CAO Qing-he XIE Yi-ping WANGXin | 2009 | Agricultural Sciences in China2009，8，10： | 28 |
| 7 | A comprehensive review of Energy Internet: basic concept,operation and planning methods, and research prospects显示文摘With the intensifying energy crisis and environmental pollution, the Energy Internet and corresponding patterns of energy use have been attracting more and more attention. In this paper, the basic concept and characteristics of the Energy Internet are summarized, and its basic structural framework is analyzed in detail. On this basis,couplings between the electric power system and other systems such as the cooling and heating system, the natural gas system, and the traffic system are analyzed, and the operation and planning of integrated energy systems in both deterministic and uncertain environments are comprehensively reviewed. Finally, the research prospects and main technical challenges of the Energy Internet are discussed. | Yijia CAO Qiang LI Yi TAN Yong LI Yuanyang CHEN Xia SHAO Yao ZOU | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，3： | 25 |
| 8 | Effect of Sancaijiangtang on plasma nitric oxide and endothelin-1 levels in patients with type 2 diabetes mellitus and vascular dementia:a single-blind randomized controlled trial显示文摘OBJECTIVE: To observe the effect of Sancaijiangtang powders on plasma nitric oxide and endothelin-1 levels. We sought to identify the common pathological link and mechanism of action for Traditional Chinese medicine in type 2 diabetes mellitus and vascular dementia,and to explicate the material basis for treating the different diseases with the same method in Traditional Chinese Medicine.METHODS: In total,168 patients with type 2 diabetes mellitus and vascular dementia were enrolled in the study,and randomly divided into two groups by simple randomization. Patients in the treatment group received oral Sancaijiangtang powders with pioglitazone hydrochloride three times daily,while patients in the control group received pioglitazone hydrochloride alone. The treatment course was for12 weeks. Mini-mental state examinations(Chinese version) and Montreal Cognitive Assessments(Beijing version) were performed,and fasting plasma glucose,fasting insulin,hemoglobin A1 c,homeostasis model assessment of insulin resistance,plasma nitric oxide and endothelin-1 levels were measured before and after the treatment.RESULTS: The post-treatment levels for all measurements in both groups were better than pre-treatment levels(P < 0.05). The post-treatment levels for all measurements in the treatment group were better than the levels measured in the control group(P < 0.05).CONCLUSION: Type 2 diabetes mellitus and vascular dementia have common pathological mechanisms for insulin resistance and endothelium dysfunction. Sancaijiangtang powders could improve the release of nitric oxide and inhibit the secretion of endothelin-1. Therefore,the material basis exists for treating the different diseases with the same method in Traditional Chinese Medicine. | Guo Qiang Cao Wenzhai Zhao Huan Zhu Yuxia Yang Dongdong Zhong Sen Chen Qiu | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 24 |
| 9 | Single-photon computational 3D imaging at 45 km显示文摘Single-photon light detection and ranging(lidar)offers single-photon sensitivity and picosecond timing resolution,which is desirable for high-precision three-dimensional(3 D)imaging over long distances.Despite important progress,further extending the imaging range presents enormous challenges because only a few echo photons return and are mixed with strong noise.Here,we tackled these challenges by constructing a high-efficiency,low-noise coaxial single-photon lidar system and developing a long-range-tailored computational algorithm that provides high photon efficiency and good noise tolerance.Using this technique,we experimentally demonstrated active single-photon 3 D imaging at a distance of up to 45 km in an urban environment,with a low return-signal level of^1 photon per pixel.Our system is feasible for imaging at a few hundreds of kilometers by refining the setup,and thus represents a step towards low-power and high-resolution lidar over extra-long ranges. | ZHENG-PING LI XIN HUANG YUAN CAO BIN WANG YU-HUAI LI WEIJIE JIN CHAO YU JUN ZHANG QIANG ZHANG CHENG-ZHI PENG FEIHU XU AND JIAN-WEI PAN | 2020 | Photonics Research2020，8，9： | 24 |
| 10 | Activation of aldehyde dehydrogenase 2 slows down the progression of atherosclerosis via attenuation of ER stress and apoptosis in smooth muscle cells显示文摘(ALDH2 ) 醛脱氢酶 2 是在醛的新陈代谢的关键 mitochondrial 酶并且可以为象心脏的肥大,心失败,心肌的 I/R 损害,灌注,心律不齐,冠的心疾病和动脉粥样硬化那样的条件有有益的心血管的效果。在这研究,我们在动脉粥样硬化和内在的机制的前进调查了 ALDH2 的角色,与 endoplasmic 蜂窝胃的一个焦点(嗯) 应力。临床的研究与冠的心疾病在 248 个病人被执行。病人根据他们的 ALDH2 遗传型被划分成二个组。基线临床的特征和冠的 angiography 被记录,并且冠的动脉 Gensini 分数是计算的。4-hydroxy-2-nonenal (4-HNE ) 的浆液层次被检测。临床的学习表明变异的 ALDH2 遗传型是为冠的心疾病的一个独立风险因素。ALDH2 基因多型性仔细与动脉粥样硬化和冠的动脉狭窄的严厉被联系。4-HNE 的浆液层次比在有野类型的 ALDH2 遗传型的病人在有变异的 ALDH2 遗传型的病人是显著地更高的。作为一在里面动脉粥样硬化的 vitro 模型,老鼠光滑的肌肉房间( SMC )与 oxygenized 被对待低密度的脂蛋白( ox-LDL )它显著地提高了层次嗯标记调整葡萄糖的 protein78 ( GRP78 ),蛋白质 kinase 象R一样嗯 kinase (津贴), phosphorylated 真核细胞的翻译开始因素子单元( p-eIF2 ),激活的抄写 factor-4 ( ATF-4 ), CEBP 相应蛋白质(砍)和在房间的 4-HNE 。所有 ox-LDL-induced 回答显著地面对 Alda-1 (激活代理人的 ALDH2 ) 被稀释,并且面对 daidzin (一个 ALDH2 禁止者) 加重了。而且,有 ALDH2 使活跃之物 Alda-1 的预告的处理显著地减少了 ox-LDL-induced apoptosis。同样, ALDH2 的 overexpression 保护了 SMC 免于 ox-LDL-induced 嗯应力象一样嗯导致压力的 apoptosis。这些调查结果建议 ALDH2 可以经由变细减缓动脉粥样硬化的前进嗯在光滑的肌肉房间的应力和 apoptosis。 | Mei-yan YANG Ya-bin WANG Bo HAN Bo YANG Yu-wei QIANG Yan ZHANG Zhao WANG Xu HUANG Jie LIU Yun-dai CHEN Jun REN Feng CAO Yong XU | 2018 | Acta Pharmacologica Sinica2018，39，1： | 22 |
| 11 | Diverse modes of clonal evolution in HBV-related hepatocellular carcinoma revealed by single-cell genome sequencing显示文摘Hepatocellular 癌(HCC ) 是癌症实质词法,基因并且 phenotypic 差异。然而,我们不理解在 intratumor 异质和肿瘤的联系词法 / 组织学的特征之间的关系。用介绍 96 个肿瘤房间(30-36 各个) 和 15 个正常的肝房间(5 各个) 的单个房间的整个染色体的定序,与联系 HBV 的 HCC 从三个男病人收集了,我们证实拷贝数字变化在 hepatocarcinogenesis 早发生,但是此后在整个肿瘤仍然保持相对稳定前进。重要地,我们证明特定的 HCC 能具有 monoclonal 或 polyclonal 起源。有汇合的 multinodular 形态学的肿瘤是典型 polyclonal 肿瘤并且显示最高的 intratumor 异质。除了 mutational 和拷贝数字侧面,我们把了用导出 HBV 的外国 genomic 标记的 HCC 的同种细胞的起源。在 monoclonal HCC,所有肿瘤单身者房间展出一样的 HBV 集成,显示 HBV 集成是一个早司机事件并且在肿瘤前进期间仍然保持极其稳定。另外,我们的结果显示那两个都转移,迟了的传播并且早播种当模特儿,在 HCC 有一个角色前进。尤其是,开始的克隆传播的早 intrahepatic 导致同步 multifocal 肿瘤的形成。同时,我们在 HCC 识别了潜在的司机基因 ZNF717,它展出变化的高频率在单个房间并且人口铺平,,通过调整 IL-6/STAT3 小径行动的肿瘤 suppressor。这些调查结果热点多重不同肿瘤在 HCC 的进化机制,它为特定的处理策略建议需要。 | Meng Duan, Shu Zhang, Zhichao Wang, Jieyi Shi, Longzi Liu, Xiaoying Wang, Aiwu Ke, Jian Zhou, Jia Fan, Qiang Gao Junfeng Hao, Chong Li Sijia Cui Daniel L Worthley Ya Cao Ruibin Xi Xiaoming Zhang Jian Zhou, Jia Fan Qiang Gao | 2018 | Cell Research2018，28，3： | 21 |
| 12 | Prognostic analysis of patients with gastrointestinal stromal tumors: a single unit experience with surgical treatment of primary disease显示文摘背景胃肠的 stromal 肿瘤(大意) ,胃肠的道的间充质的肿瘤的最普通的类型,是一个最近公认的肿瘤。大意的生物行为是高度可变的。外科的切除术为大意仍然是主要治疗。在这研究,我们回顾地与 181 个大意病人一起分析了我们的外科的经验决定治疗和病理学的特征和这些大意 patients.Methods 的预后因素的效果在 Ren 收到了在1999年1月和2007年12月之间的外科的切除术的有大意的 181 个病人的 clinicopathological 特征和后续数据 Ji 医院回顾地被考察。包括 CD117 (工具包) 的 Immunohistochemical 污点, CD34,和另外的标记被使用。肿瘤尺寸,有丝分裂的索引和另外的病理学的参数被记录。根据 NIH 风险组层化系统的一致基于最大的肿瘤尺寸和有丝分裂的索引(每 50 高力量地),肿瘤被分类进 very-low-risk 组( 15 个肿瘤,8.3%),低风险的组( 48 ,26.5%),中间风险的组( 52 ,28.7%)并且高风险的组( 66 ,36.5%)。预示的因素被考克斯分析包括年龄,性别,肿瘤尺寸,肿瘤地点,有丝分裂的索引, NIH 范畴和外科的过程分析。结果(59.1%) 107 181 个肿瘤位于胃, 51 (28.2%) 在小肠, 9 (5.0%) 在冒号和直肠,并且 14 (7.7%) 在另外的地点包括网膜和肠系膜。病人的中部的年龄是 58 (范围, 24-84 ) 年,和 102 个病人(56.4%) 是男性的。肿瘤尺寸从 0.5 ~ 30 厘米,当吝啬的尺寸是 7.02 厘米时。转移在 7 个病人被发现。(97.2%) 176 181 个病人经历了激进的切除术,并且在他们之中, 26 个病人与邻近的机关支持者一起收到了广泛的切除术到肿瘤。为在 immunostaining 的 KIT 蛋白质(CD117 ) 的积极的率是 94.5%(171/181 ) ,当那为 CD34 是 86.2% 时(156/181 ) 。1- , 3- ,和 181 个病人的 5 年的幸存率被估计分别地是 95.2% , 87.9% 和 78.5% 。在 multivisceral 切除术的年龄,肿瘤尺寸,肿瘤地点,有丝分裂的索引, NIH 范畴,和存在或缺席有重要差别(P < 0.05 ) 。但是在在这些组之间的性别没有重要差别。比例的模型揭示了的考克斯危险那个先进临床的阶段和大肿瘤尺寸贡献了更坏的预后。因为复发和转移或高复发风险,与 imatinib 被对待的病人显示出外科的切除术是的稳定的 disease.Conclusions 为主要大意的治疗的标准答案。NIH 分类简单、有效评估大意行为和预后。指向的治疗象 imatinib 那样,一个工具包酷氨酸 kinase 禁止者,可以在大意的治疗起一个重要作用。 | CAO Hui ZHANG Yun WANG Ming SHEN Dan-ping SHENG Zhi-yong NI Xing-zhi WU Zhi-yong LIU Qiang SHEN Yan-ying SONG Yan-yan | 2010 | Chinese Medical Journal2010，，2： | 20 |
| 13 | Natural Variation in CCD4 Promoter Underpins Species-Specific Evolution of Red Coloration in Citrus Peel显示文摘Carotenoids and apocarotenoids act as phytohormones and volatile precursors that influence plant development and confer aesthetic and nutritional value critical to consumer preference.Citrus fruits display considerable natural variation in carotenoid and apocarotenoid pigments.In this study,using an integrated genetic approach we revealed that a 5;c/s-regulatory change at CCD4b encoding CAROTENOID CLEAVAGE DIOXYGENASE 4b is a major genetic determinant of natural variation in C3 0 apocarotenoids responsible for red coloration of citrus peel.Functional analyses demonstrated that in addition the known role in synthesizing 3-citraurin,CCD4b is also responsible for the production of another important C3 0 apocarotenoid pigment,p-citraurinene.Furthermore,analyses of the CCD4b promoter and transcripts from various citrus germplasm accessions established a tight correlation between the presence of a putative 5'c/s-regulatory enhancer within an MITE transposon and the enhanced allelic expression of CCD4b in C3 0 apocarotenoid-rich red-peeled accessions.Phylogenetic analysis provided further evidence that functional diversification of CCD4b and naturally occurring variation of the CCD4b promoter resulted in the stepwise evolution of red peels in mandarins and their hybrids.Taken together,our findings provide new insights into the genetic and evolutionary basis of apocarotenoid diversity in plants,and would facilitate breeding efforts that aim to improve the nutritional and aesthetic value of citrus and perhaps other fruit crops. | Xiongjie Zheng Kaijie Zhu Quan Sun Weiyi Zhang Xia Wang Hongbo Cao Meilian Tan Zongzhou Xie Yunliu Zeng Junli Ye Lijun Chai Qiang Xu Zhiyong Pan Shunyuan Xiao Paul D.Fraser Xiuxin Deng | 2019 | Molecular Plant2019，12，9： | 18 |
| 14 | Synthesis of spherical LiNi_(0.8)Co_(0.15)Al_(0.05)O_2 cathode materials for lithium-ion batteries by a co-oxidation-controlled crystallization method显示文摘球形的 Ni0.8Co0.15Al0.05OOH 先锋,由一个 co-oxidation-controlled 结晶化方法准备了,被用来综合 LiNi0.8Co0.15Al0.05O2。获得的 LiNi0.8Co0.15Al0.05O2 材料看了优秀电气化学的性能,与 193.5 mAh/g 的一个起始的分泌物能力和在 50 个周期以后的 95.1% 的能力保留什么时候以在 2.8 和 4.3 V 之间的 0.2 C 率骑车了。 | Wan Min Liu Guo Rong Hu Zhong Dong Peng Ke Du Yan Bing Cao Qiang Liu | 2011 | Chinese Chemical Letters2011，22，9： | 17 |
| 15 | Reproductive traits associated with invasiveness in Conyza sumatrensis显示文摘Conyza sumatrensis (Retz.) E. Walker, a member of Asteraceae, is a highly invasive species. However, its reproduction biology remains poorly known. To understand the role of reproductive traits in successful invasion of the species, we studied several traits of its reproductive system: the miniature capitulum and gynomonoecious sexual system, the biology and phenology of capitula and florets, pollen/ovule ratio, the mating system (self-compatibility), flower visitors, physical traits and dispersal potential of achenes, germination potential of achenes from manually pollinated capitula, and the association of these traits with invasiveness. Our study showed that the reproductive traits of autonomous seed production, versatile mating system of self- and cross-pollination, and generalized pollination system might contribute to the species' successful invasive capability. The invasiveness was further enhanced by the high and rapid production of achenes, as well as the high percentage, rapid germination rate and high dispersal capability of achenes. It was concluded that in annual or winter-annual weeds, autonomous seed production contributed significantly to the invasiveness of the species. | jian-Hua HAO Sheng QIANG Qian-Qian LIU Fei CAO | 2009 | Journal of Systematics and Evolution2009，47，3： | 13 |
| 16 | A RELAXED HSS PRECONDITIONER FOR SADDLE POINT PROBLEMS FROM MESHFREE DISCRETIZATION*显示文摘在这,切开的纸,放松的 Hermitian 和 skew-Hermitian (RHSS ) preconditioner 从没有元素的 Galerkin (EFG ) discretization 方法为僵绳点问题被建议。EFG 方法是为解决部分微分方程的最广泛地使用的 meshfree 方法之一。RHSS preconditioner 比著名 HSS preconditioner 更近很被构造到系数矩阵,导致一次 RHSS 定点重复。RHSS 重复的集中被分析并且一个最佳的参数,它最小化光谱重复矩阵的半径被描述。使用 RHSS preconditioner 加速一些 Krylov subspace 方法(相似 GMRES ) 的集中也被学习。理论分析证明 RHSS preconditioned 矩阵的特征值在积极间隔真实、定位。特徵向量分发和 preconditioned 矩阵的最小的多项式的度的上面的界限被获得。一个实际参数在实现 RHSS preconditioner 被建议。最后,一些数字实验被说明显示出新 preconditioner 的有效性。[从作者抽象] | Yang Cao Linquan Yao Meiqun Jiang Qiang Niu | 2013 | Journal of Computational Mathematics2013，31，4： | 12 |
| 17 | High Temperature Strain Structures and Quartz C-Axis Fabrics from Mylonitic Rocks in the Ailaoshan-Red River Shear Zone,Yunnan,and Their Tectonic Implication显示文摘Ailaoshan 红的河(ASRR ) 砍地区是考虑了东方西藏的现在的构造框架的主要东南亚洲构造断绝之一。几座变形山岳沿着 shear 地区线性地是分布式的,例如从北方的 Xuelongshan, Diancangshan, Ailaoshan 和到南方的天 Nui 反对 Voi。他们为构造进化忍受证据的很多线东方在在不同构造舞台的不同外壳的层次西藏。争吵仍然沿着 ASRR 在有变态的变丑结构,微观结构和他们的关系上存在。在这,纸详细说明了微结构和 EBSD (电子 Backscattered 衍射) 从沿着 ASRR 的不同山岳的一些高度砍的花岗石的岩石的织物分析被进行。高温度结构和微观结构在 unsheared 片麻岩被保存,在微弱地砍的捕虏体或在高度砍的岩石(糜棱岩) 的一些部分。高温度石英 c 轴织物的几种类型显示出对称的模式或转变从对不均匀的模式对称。前者在在印第安人欧亚的构造相互作用的一个早阶段的地区性的弄短期间被归因于同轴的变丑,后者与从同轴的压缩的转变有关到在让侧面的 post-collisional ASRR 期间砍的 noncoaxial 砍。 | LIU Junlai TANG Yuan XIA Haoran GUO Qiang TRAN My Dung CAO Shuyun WU Hujun WU Wenbin ZHANG Zhaochong ZHAO Zhidan | 2010 | Acta Geologica Sinica(English Edition)2010，84，6： | 12 |
| 18 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 19 | High Strength Silicon Carbide Foams and Their Deformation Behavior显示文摘碳化矽(原文如此) 有连续地连接的开房间的结构的泡沫为他们的机械表演作好准备并且描绘。SiCfoams 的表观虎度在大约 0.4 和 1.3 g/cm^3 之间被控制,与相应压缩强度从从大约 8 ~ 30 MPa 的大约 13 ~ 60 MPa 和曲折力量。压缩测试原文如此,泡沫与仅仅一个线性橡皮的区域产出压力紧张曲线,它与在文学在陶器的泡沫上报导的那些不同。这能可能与好、稠密、高的力量微观结构被归因于细丝的存在。原文如此并且细丝对装载使用同类地作出回应。 | Chong TIAN Jinsong ZHANG Xiaoming CAO Qiang LIU Wanping HU | 2006 | Journal of Materials Science & Technology2006，22，2： | 11 |
| 20 | Harmine induces apoptosis in HepG2 cells via mitochondrial signaling pathway显示文摘BACKGROUND:Harmine has antitumor and antinociceptive effects,and inhibits human DNA topoisomerase.However no detailed data are available on the mechanisms of action of harmine in hepatocellular carcinoma.This study aimed to investigate the effects of harmine on proliferation and apoptosis and the underlying mechanisms in the human hepatocellular carcinoma cell line HepG2.METHODS:The proliferation of HepG2 cells was determined by the cell counting kit-8 (CCK-8) assay and the clone formation test.The morphology of HepG2 cells was examined using fluorescence microscopy after Hoechst 33258 staining Annexin V/propidium iodide (PI) was used to analyze apoptosis and PI to analyze the cell cycle.Western blotting was used to assess expression of the apoptosis-regulated genes Bcl-2,Bax,Bcl-xl,Mcl-1,caspase-3,and caspase-9 Mitochondrial transmembrane potential (Ψ m) was determined using JC-1.RESULTS:Harmine inhibited the proliferation of HepG2 cells in a dose-dependent manner.Hoechst 33258 staining revealed nuclear fragmentation and chromosomal condensation,cell shrinkage,and attachment loss in HepG2 cells treated with harmine.The percentage of the sub/G1 fraction was increased in a concentration-dependent manner,indicating apoptotic cell death.PI staining showed that harmine changed the cell cycle distribution,by decreasing the proportion of cells inG0/G1 and increasing the proportion in S and G2/M.Harmine induced apoptosis in a concentration-dependent manner,with rates of 20.0%,32.7% and 64.9%,respectively.JC-1 revealed a decrease in Ψ m.Apoptosis of HepG2 cells was associated with caspase-3 and caspase-9 activation,down-regulation of Bcl-2,Mcl-1,and Bcl-xl,and no change in Bax.CONCLUSIONS:Harmine had an anti-proliferative effect in HepG2 cells by inducing apoptosis.Mitochondrial signal pathways were involved in the apoptosis.The cancer-specific selectivity shown in this study suggested that harmine is a promising novel drug for human hepatocellular carcinoma. | Ming-Rong Cao,Qiang Li,Zhi-Long Liu,Hui-Hui Liu,Wei Wang,Xiao-Li Liao,Yun-Long Pan and Jian-Wei Jiang Department of General Surgery,First Affiliated Hospital,Jinan University,Guangzhou 510632,China Department of Anesthesiology,First Affiliated Hospital,Guangzhou University of TCM,Guangzhou 510632,China Department of Biochemistry,Medical College of Jinan University,Guangzhou 510632,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，6： | 11 |
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