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| 1 | Dapper1 promotes autophagy by enhancing the Beclinl -Vps34-Atg14L complex formation显示文摘 | Benvu Ma Weipeng Cao Wenxia Li Chan Gao Zhen Qi Yan Zhao Jun Du Hua Xue Junya Peng Jun Wen Hua Chen Yuanheng Ning Lei Huang Hong Zhang Xiang Gao Li Yu Ye-Guang Chen | 2014 | Cell Research2014，24，8： | 12 |
| 2 | Single-cell transcriptomic atlas of primate cardiopulmonary aging显示文摘Aging is a major risk factor for many diseases,especially in highly prevalent cardiopulmonary comorbidities and infectious diseases including Coronavirus Disease 2019(COVID-19).Resolving cellular and molecular mechanisms associated with aging in higher mammals is therefore urgently needed.Here,we created young and old non-human primate single-nucleus/cell transcriptomic atlases of lung,heart and artery,the top tissues targeted by SARS-CoV-2.Analysis of cell type-specific aging-associated transcriptional changes revealed increased systemic inflammation and compromised virus defense as a hallmark of cardiopulmonary aging.With age,expression of the SARS-CoV-2 receptor angiotensin-converting enzyme 2(ACE2)was increased in the pulmonary alveolar epithelial barrier,cardiomyocytes,and vascular endothelial cells.We found that interleukin 7(IL7)accumulated in aged cardiopulmonary tissues and induced ACE2 expression in human vascular endothelial cells in an NF-κB-dependent manner.Furthermore,treatment with vitamin C blocked IL7-induced ACE2 expression.Altogether,our findings depict the first transcriptomic atlas of the aged primate cardiopulmonary system and provide vital insights into age-linked susceptibility to SARS-CoV-2,suggesting that geroprotective strategies may reduce COVID-19 severity in the elderly. | Shuai Ma Shuhui Sun Jiaming Li Yanling Fan Jing Qu Liang Sun Si Wang Yiyuan Zhang Shanshan Yang Zunpeng Liu Zeming Wu Sheng Zhang Qiaoran Wang Aihua Zheng Shuguang Duo Yang Yu Juan Carlos Izpisua Belmonte Piu Chan Qi Zhou Moshi Song Weiqi Zhang Guang-Hui Liu | 2021 | Cell Research2021，31，4： | 10 |
| 3 | Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration显示文摘Accumulating evidence indicates an association between the circadian clock and the aging process.However,it remains elusive whether the deregulation of circadian clock proteins underlies stem cell aging and whether they are targetable for the alleviation of aging-associated syndromes.Here,we identified a transcription factor-independent role of CLOCK,a core component of the molecular circadian clock machinery,in counteracting human mesenchymal stem cell(hMSC)decay.CLOCK expression was decreased during hMSC aging.In addition,CLOCK deficiency accelerated hMSC senescence,whereas the overexpression of CLOCK,even as a transcriptionally inactive form,rejuvenated physiologically and pathologically aged hMSCs.Mechanistic studies revealed that CLOCK formed complexes with nuclear lamina proteins and KAP1,thus maintaining heterochromatin architecture and stabilizing repetitive genomic sequences.Finally,gene therapy with lentiviral vectors encoding CLOCK promoted cartilage regeneration and attenuated age-related articular degeneration in mice.These findings demonstrate a noncanonical role of CLOCK in stabilizing heterochromatin,promoting tissue regeneration,and mitigating aging-associated chronic diseases. | Chuqian Liang Zunpeng Liu Moshi Song Wei Li Zeming Wu Zehua Wang Qiaoran Wang Si Wang Kaowen Yan Liang Sun Tomoaki Hishida Yanning Cai Juan Carlos lzpisua Belmonte Pedro Guillen Piu Chan Qi Zhou Weiqi Zhang Jing Qu Guang-Hui Liu | 2021 | Cell Research2021，31，2： | 8 |
| 4 | Clinical and Familial Characteristics of Ten Chinese Patients with Fatal Family Insomnia显示文摘Objective Fatal familial insomnia(FFI) is an autosomal dominant prion disease characterized clinically by inattention,sleep loss,dysautonomia,and motor signs.This study is aimed to investigate clinical and familial characteristics of ten Chinese Patients with FFI.Methods We identified ten FFI cases from the surveillance network for Creutafeldt-Jakob disease(CJD) in China.Final diagnosis of FFI cases was made in accordance with the WHO criteria for CJD.The main clinical features and family histories of these ten FFI cases were analyzed.Results The median age of ten cases at onset was 38 years(from 19 to 55).The foremost symptoms seemed to be various,including sleep disturbances,vision disorder,dizziness and anorexia.Sleep disturbances appeared in all cases and lasted in the whole clinical courses.Progressive sympathetic symptoms,memory loss,movement disturbances,myoclonus and hypertension were also frequently observed.The median duration of the disease was 9.5 months.EEG and MRI did not figure out special abnormality.14-3-3 protein in CSF was positive in five out of eight tested patients.Clear family histories were identified in 8 patients.Conclusion The data from our study confirm that the Chinese FFI cases have similar clinical characteristics as that of the Caucasian cases.Compared with other genetic CJD associated mutations,the genetic frequencies of D178N in PRNP are apparently high among the Chinese cases. | SHI Qi CHEN Cao GAO Chen TIAN Chan ZHOU Wei ZHANG BaoYun HAN Jun DONG Xiao Ping | 2012 | Biomedical and Environmental Sciences2012，25，4： | 8 |
| 5 | Deformation behavior of Zr-based bulk metallic glass and composite in the supercooled liquid region显示文摘A Zr-based bulk metallic glass (BMG) with a composition of (Zr75Cu25)78.5Ta4Ni10Al7.5 and a bulk metallic glass matrix composite (BMGC) with a composition of (Zr75Cu25)74.5Ta8Ni10Al7.5 have been prepared by copper-mold casting. The compres-sive deformation behavior of the BMG and BMGC was investigated in the super-cooled region at different temperatures and various strain rates ranging from 8×10-4s-1 to 8×10-2s-1. It was found that both the strain rate and test temperature signifi-cantly affect the deformation behavior of the two alloys. The deformation follows Newtonian flow at low strain rates but non-Newtonian flow at high strain rates. The deformation mechanism for the two kinds of alloys was discussed in terms of the transition state theory. | CHEN Qi LIU Lin CHAN K.C. | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，4： | 8 |
| 6 | Digital assembly technology based on augmented reality and digital twins: a review显示文摘Product assembly simulation is considered as one of the key technologies in the process of complex product design and manufacturing.Virtual assembly realizes the assembly process design,verification,and optimization of complex products in the virtual environment,which plays an active and effective role in improving the assembly quality and efficiency of complex products.In recent years,augmented reality(AR)and digital twin(DT)technology have brought new opportunities and challenges to the digital assembly of complex products owing to their characteristics of virtual reality fusion and interactive control.This paper expounds the concept and connotation of AR,enumerates a typical AR assembly system structure,analyzes the key technologies and applications of AR in digital assembly,and notes that DT technology is the future development trend of intelligent assembly research. | Chan QIU Shien ZHOU Zhenyu LIU Qi GAO Jianrong TAN | 2019 | Virtual Reality & Intelligent Hardware2019，1，6： | 7 |
| 7 | Single-nucleus transcriptomic landscape of primate hippocampal aging显示文摘The hippocampus plays a crucial role in learning and memory,and its progressive deterioration with age is functionally linked to a variety of human neurodegenerative diseases.Yet a systematic profiling of the aging effects on various hippocampal cell types in primates is still missing.Here,we reported a variety of new aging-associated phenotypic changes of the primate hippocampus.These include,in particular,increased DNA damage and heterochromatin erosion with time,alongside loss of proteostasis and elevated inflammation.To understand their cellular and molecular causes,we established the first single-nucleus transcriptomic atlas of primate hippocampal aging.Among the 12 identified cell types,neural transiently amplifying progenitor cell(TAPC)and microglia were most affected by aging.In-depth dissection of gene-expression dynamics revealed impaired TAPC division and compromised neuronal function along the neurogenesis trajectory;additionally elevated pro-inflammatory responses in the aged microglia and oligodendrocyte,as well as dysregulated coagulation pathways in the aged endothelial cells may contribute to a hostile microenvironment for neurogenesis.This rich resource for understanding primate hippocampal aging may provide potential diagnostic biomarkers and therapeutic interventions against age-related neurodegenerative diseases. | Hui Zhang Jiaming Li Jie Ren Shuhui Sun Shuai Ma Weiqi Zhang Yang Yu Yusheng Cai Kaowen Yan Wei Li Baoyang Hu Piu Chan Guo-Guang Zhao Juan Carlos Izpisua Belmonte Qi Zhou Jing Qu Si Wang Guang-Hui Liu | 2021 | Protein & Cell2021，12，9： | 5 |
| 8 | Deciphering primate retinal aging at single-cell resolution显示文摘Dear Editor, The retina is a light-sensitive highly-organized tissue,which is vulnerable to aging and age-related retinal diseases.Specifically,progressive retinal degeneration leads to visual function deterioration and vision impairment in the elderly(Lin et al.,2016).In diseases such as age-related macular degeneration(AMD),retinitis pigmentosa(RP)and diabetic retinopathy(DR),pathological process lacking effective treatments profoundly and negatively impact on the quality of life in the elderly(Lin et al.,2016;Chen et al.,2019).Thus,an in-depth molecular assessment of the mechanisms driv-ing retinal aging is of urgent scientific and medical importance. | Si Wang Yuxuan Zheng Qingqing Li Xiaojuan He Ruotong Ren Weiqi Zhang Moshi Song Huifang Hu Feifei Liu Guoqiang Sun Shuhui Sun Zunpeng Liu Yang Yu Piu Chan Guo-Guang Zhao Qi Zhou Guang-Hui Liu Fuchou Tang Jing Qu | 2021 | Protein & Cell2021，12，11： | 4 |
| 9 | Casein kinase Ⅱ interacts with prion protein in vitro and forms complex with native prion protein in vivo显示文摘最必要、关键的步在能递送的海绵状的 encephalopathy 的致病期间是到病理学的 isoform 的细胞的 prion 蛋白质的 conformational 变化。酷蛋白 kinase II (CK2 ) 是一无所不在地表示了并且 evolutionarily 保存了为生存能力是必要的多种的蛋白质 kinase。探索在 CK2 和 prion 蛋白质(PrP ) 之间的可能的分子的相互作用,人的 CK2α 和 CK2β 的全身的序列互补 DNA 作为模板从房间线 SH-SY5Y 用彻底的送信人 RNA 与反向的抄写聚合酶链反应被放大;然后,熔化蛋白质 histidine-CK2α 和谷胱甘肽 S-transferase-histidine-CK2β 在 Escherichia 关口 i 被表示。在 CK2 和 PrP 之间的相互作用与 co-immunoprecipitation 和下拉试金被评估。结果证明 recombinant PrP 与 CK2α ,然而并非与 CK2β 明确地跳了。在仓鼠大脑的本国的 CK2 和 PrP 与对方一起交往了,形成蛋白质建筑群。从正常大脑的 PrP (diglycosylated, monoglycosylated 和 unglycosylated PrP ) 的三种不同 glycosylated 形式与 CK2α 子单元交往了,尽管 unglycosylated PrP 似乎与 CK2α 子单元有一个更强壮的有约束力的能力。负责与 CK2α 交往的领域在 PrP 的 C 终端片断被定位(残余 91 231 ) 。这研究为在 PrP 和 CK2α 之间的分子的相互作用建议了可靠试验性的数据(两个在 recombinant 和本国的范畴) ,为进一步估计 PrP-CK2 相互作用的潜在的生物意义的科学线索,和在 prion 疾病的致病的 CK2 的可能的角色。 | Jianming Chen Chen Gao Qi Shi Guirong Wang Yanjun Lei Bing Shan Baoyun Zhang Chenfang Dong SongShi Xin Wang Chan Tian Jun Han Xiaoping Dong | 2008 | Acta Biochimica et Biophysica Sinica2008，40，12： | 3 |
| 10 | The First Chinese Case of Creutzfeldt-Jakob Disease with Mutation of E200K in PRNP显示文摘Objective To investigate epidemiological, clinical and genetic features of the first Chinese case of Creutzfeldt-Jakob disease (CJD ) with mutation of E200K in PRNP. Methods The general epidemiological and clinical data were collected; CSF 14-3-3 protein was analyzed by Western blot; The PRNP was amplified by PCR and analyzed. Results A missense mutation in codon 200 (E200K) of the PRNP was identified in this patient; CSF 14-3-3 protein was positive; sleep disturbance was the initial sign and the other symptoms gradually appeared, including memory loss, dizziness and ataxia. Conclusion The CJD patient who was first reported in China has a missense mutation in codon 200 (E200K) of the PRNP, and the codon 129 is a methionine homozygous genotype. | CHEN GAO QI SHI WEI ZHOU CHAN TIAN HHUI-YING JIANG BAO-YUN ZHANG JUN HAN XIAO-PING DONG | 2010 | Biomedical and Environmental Sciences2010，23，2： | 3 |
| 11 | A single-cell transcriptomic atlas of primate pancreatic islet aging显示文摘Aging-related degeneration of pancreatic islet cells contributes to impaired glucose tolerance and diabetes.Endocrine cells age heterogeneously,complicating the efforts to unravel the molecular drivers underlying endocrine aging.To overcome these obstacles,we undertook single-cell RNA sequencing of pancreatic islet cells obtained from young and aged non-diabetic cynomolgus monkeys.Despite sex differences and increased transcriptional variations,agedβ-cells showed increased unfolded protein response(UPR)along with the accumulation of protein aggregates.We observed transcriptomic dysregulation of UPR components linked to canonical ATF6 and IRE1 signaling pathways,comprising adaptive UPR during pancreatic aging.Notably,we found aging-relatedβ-cell-specific upregulation of HSP90 B1,an endoplasmic reticulum-located chaperone,impeded high glucose-induced insulin secretion.Our work decodes aging-associated transcriptomic changes that underlie pancreatic islet functional decay at single-cell resolution and indicates that targeting UPR components may prevent loss of proteostasis,suggesting an avenue to delayingβ-cell aging and preventing aging-related diabetes. | Jingyi Li Yuxuan Zheng Pengze Yan Moshi Song Si Wang Liang Sun Zunpeng Liu Shuai Ma Juan Carlos Izpisua Belmonte Piu Chan Qi Zhou Weiqi Zhang Guang-Hui Liu Fuchou Tang Jing Qu | 2021 | National Science Review2021，8，2： | 3 |
| 12 | Trending IC design directions in 2022显示文摘For the non-stop demands for a better and smarter society, the number of electronic devices keeps increasing exponentially;and the computation power, communication data rate, smart sensing capability and intelligence are always not enough. Hardware supports software, while the integrated circuit(IC) is the core of hardware. In this long review paper, we summarize and discuss recent trending IC design directions and challenges, and try to give the readers big/cool pictures on each selected small/hot topics. We divide the trends into the following six categories, namely, 1) machine learning and artificial intelligence(AI) chips, 2) communication ICs, 3) data converters, 4) power converters, 5) imagers and range sensors, 6) emerging directions. Hope you find this paper useful for your future research and works. | Chi-Hang Chan Lin Cheng Wei Deng Peng Feng Li Geng Mo Huang Haikun Jia Lu Jie Ka-Meng Lei Xihao Liu Xun Liu Yongpan Liu Yan Lu Kaiming Nie Dongfang Pan Nan Qi Sai-Weng Sin Nan Sun Wenyu Sun Jiangtao Xu Jinshan Yue Milin Zhang Zhao Zhang | 2022 | Journal of Semiconductors2022，43，7： | 3 |
| 13 | Doppel-induced cytotoxicity in human neuronal SH-SY5Y cells is antagonized by the prion protein显示文摘Doppel (Dpl ) 由于结构、生物化学的类似是象蛋白质一样的 prion (PrP ) ;然而, Dpl 和 PrP 的自然功能仍然保持不清楚。在这研究,编码 Dpl 蛋白质的一个 531-bp 人 PRND 基因序列从人的外部血白细胞被放大。全身、各种各样的截断的人的 Dpl 和 PrP 蛋白质从 Escherichia 被表示并且净化 coli。全身的 Dpl 的补充导致了显著 cytotoxicity,和负责的区域到人的 neuroblastoma 房间 SH-SY5Y 上因为它的 cytotoxicity 在 Dpl 的中间的片断被印射[氨基酸(aa ) 81122 ] 。有趣地,导致 Dpl 的 cytotoxicity 被全身的野类型的 PrP 的存在反对。PrP 异种的碎片上的分析证明 N 终端碎裂(aa 2390 ) PrP 为保护的活动负责。有 Dpl 在 SH-SY5Y 房间上导致了象 Dpl 一样 cytotoxicity 的类似的第二等的结构的截断的 PrP (PrP32121 ) 。而且,铜离子的绑定能在导致 Dpl 的 cytotoxicity 上提高 PrP 的反对效果。Apoptosis 试金表明 Dpl 导致的 cytotoxicity 通过 apoptotic 机制发生了。这些结果建议 Dpl 的功能对 PrP 而非 synergistic 对抗。 | Ping Li Chenfang Dong Yanjun Lei Bing Shan Xinli Xiao Huiying Jiang Xin Wang Chen Gao Qi Shi Kun Xu Chan Tian Jun Han Xiaoping Dong | 2009 | Acta Biochimica et Biophysica Sinica2009，41，1： | 3 |
| 14 | Over-expression of nm23-H1 in HeLa cells provides cells with higher resistance to oxidative stress possibly due to raising intracellular p53 and GPX显示文摘瞄准:决定反肿瘤因素 nm23 是否与反氧化是相关的。方法:全身的人的 nm23-H1 被克隆进哺乳动物表示的向量并且短暂地介绍了房间进 HeLa。结果:反应的氧种类(ROS ) 显著地低级的 A 在细胞被检测过去表示的 nm23-H1。3-(4,5-Dimethylthiazol-2-yl )-2,5-diphenyltetrazolium 溴化物和尝试平底锅蓝色试金发现有一个 nm23-H1-expressing 原生质标志的房间 transfected 有更高的生存能力和更强壮的抵抗到氧化应力。Immunoprecipitation 测试表明内长的 nm23-H1 与 p53 形成了蛋白质建筑群。而且, p53 的细胞内部的层次和 p53-regulatedgene GPX1 显然在表示 nm23-H1 上在房间被增加。下面在在表示 nm23-H1 上的房间的 p53 的规定导致了更高细胞的 ROS 水平和更低的房间生存能力。结论:调查结果建议 nm23-H1 可以对氧化应力充当一个细胞的保护者,可能触发 p53 相关的抗氧化的小径。 | Run AN Yong-lie CHU Chan TIAN Xiao-xia DAI Jing-hong CHEN Qi SHI Jun HAN Xiao-ping DONG | 2008 | Acta Pharmacologica Sinica2008，29，12： | 2 |
| 15 | Establishment of Hamster-and Human-PRNP Transgenic Mice显示文摘Objective To create transgenic mice expressing hamster‐ and human‐PRNP as a model for understanding the physiological function and pathology of prion protein (PrP),as well as the mechanism of cross‐species transmission of transmissible spongiform encephalopathies (TSEs).Methods Hamster and human‐PRNP transgenic mice were established by conventional methods.The copy number of integrated PRNP in various mouse lines was mapped by real‐time PCR.PRNP mRNA and protein levels were determined by semi‐quantitative RT‐PCR,real‐time RT‐PCR,and western blot analysis.Histological analyses of transgenic mice were performed by hematoxylin and eosin (H & E) staining and immunohistochemical (IHC) methods.Results Integrated PRNP copy number in various mouse lines was 53 (Tg‐haPrP1),18 (Tg‐huPrP1),3 (Tg‐huPrP2),and 16 (Tg‐huPrP5),respectively.Exogenous PrPs were expressed at both the transcriptional and translational level.Histological assays did not detect any abnormalities in brain or other organs.Conclusion We have established one hamster‐PRNP transgenic mouse line and three human‐PRNP transgenic mouse lines.These four transgenic mouse lines provide ideal models for additional research. | GONG Han Shi TIAN Chan ZHANG Bao Yun WANG Zhao Yun XIE Wu Ling JING Yuan Yuan GAO Chen JIANG Hui Ying SHI Qi LIU Yong DONG Xiao Ping | 2011 | Biomedical and Environmental Sciences2011，24，6： | 2 |
| 16 | Does diffusion kurtosis imaging lead to better neural tissue characterization? A rodent brain maturation study显示文摘 | Matthew M. Cheung Edward S. Hui Kevin C. Chan Joseph A. Helpern Liqun Qi Ed X. Wu | 2008 | Neuroimage2008，，2： | 2 |
| 17 | Plasma metabolomics combined with personalized diagnosis guided by Chinese medicine reveals subtypes of chronic heart failure显示文摘Background:Chronic heart failure(CHF)is characterized by insufficient blood supply from heart to meet the body’s metabolic demands.Integrating Western and traditional Chinese medicine to treat CHF has proved a validated therapeutic approach.In recent years,metabolomics has been regarded as a potential platform to provide biomarkers for diseasesubtypes.Objective:To examine 38 patients,combined NMR plasma metabolomics and traditional Chinese medicine diagnosis in order to identify diagnostic biomarkers for two CHF syndrome subtypes.Methods:After processing the spectra,orthogonal partial least square discriminant analysis was performed,and the contributing NMR signals were analyzed using Y-scrambling statistical validation with good reliability.Results:Plasma metabolic patterns of yin deficiency and yang deficiency patients were clearly discriminated.The yin-deficiency group had increased level of lactate,glycoprotein,lipoprotein and lower levels of glucose,valine and proline.The yang-deficiency group had higher levels of lactate,glycoprotein and pyruvic acid,and lower levels of glucose and lipoprotein.Potential biomarkers of CHF based on the two traditional Chinese medicine syndromes indicated alternative modes of metabolites and metabolic pathways in the disease,e.g.dysfunction of energy utilization and disturbance in fatty acids,amino acids.Conclusion:This study suggests that combining metabolomics with traditional Chinese medicine diagnosis can reveal metabolic signatures for CHF syndrome subtypes.The plasma metabolites identified might be of special clinical relevance for subtypes of CHF,which could lead to further understanding of mechanisms involved and an improvement in personalized treatment for CHF. | Juan Wang Shuzhen Guo Kuo Gao Qi Shi Bangze Fu Chan Chen Liangtao Luo Dong Deng Huihui Zhao Wei Wang | 2015 | Journal of Traditional Chinese Medical Sciences2015，2，2： | 2 |
| 18 | Route Guardian: Constructing Secure Routing Paths in Software-Defined Networking显示文摘Software-Defined Networking(SDN) decouples the control plane and the data plane in network switches and routers, which enables the rapid innovation and optimization of routing and switching configurations. However,traditional routing mechanisms in SDN, based on the Dijkstra shortest path, do not take the capacity of nodes into account, which may lead to network congestion. Moreover, security resource utilization in SDN is inefficient and is not addressed by existing routing algorithms. In this paper, we propose Route Guardian, a reliable securityoriented SDN routing mechanism, which considers the capabilities of SDN switch nodes combined with a Network Security Virtualization framework. Our scheme employs the distributed network security devices effectively to ensure analysis of abnormal traffic and malicious node isolation. Furthermore, Route Guardian supports dynamic routing reconfiguration according to the latest network status. We prototyped Route Guardian and conducted theoretical analysis and performance evaluation. Our results demonstrate that this approach can effectively use the existing security devices and mechanisms in SDN. | Mengmeng Wang Jianwei Liu Jian Mao Haosu Cheng Jie Chen Chan Qi | 2017 | Tsinghua Science and Technology2017，22，4： | 2 |
| 19 | 抗生素使用的时间长短和使用时的生命阶段与全因/特定原因死亡风险的关系:一项前瞻性队列研究显示文摘过度使用抗生素一直是一个重要的临床问题,抗生素使用与肠道微生物菌群的改变有关,肠道菌群的改变与各种慢性疾病如心血管病和癌症的风险有关。此外,抗生素使用的时间可能是过早死亡的一个危险因素。研究者调查了成年期间使用抗生素的生命阶段和使用持续时间与全因和特定原因死亡风险的关系。该项前瞻性队列研究包括来自护士健康研究、均未患有心血管病或癌症的37516名年龄≥60岁的女性,收集其中年(40~59岁)和老年(≥60岁)使用抗生素的时间(无,<15d,15d至<2个月,或≥2个月)。研究者根据抗生素的使用时间估计10年内全因死亡率和心血管病或癌症的死亡风险比(HR)。在355918人年的随访中,研究者记录了所有原因导致的4536例死亡(包括728例心血管病死亡和1206例癌症死亡) | 刘青(译) 叶鹏(摘 审校) Heianza Y Ma W Li X Cao Y Chan A Rimm EB Hu FB Rexrode K Manson JE Qi L | 2020 | 中华高血压杂志2020，28，2： | 2 |
| 20 | An information systems view of China state enterprises显示文摘 | Dorothy G Dologite Mai Qi Fang Yu Chen Robert J Mockler Chiang-nan Chan | 1998 | Journal of Strategic Information Systems1998，7，： | 1 |
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