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| 1 | Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells显示文摘体的房间能由定义因素是进导致的 pluripotent 干细胞(iPSCs ) 的 reprogrammed。reprogramming 的低效率和 oncogenes 和病毒的向量的 genomic 集成限制了 iPSCs 的潜在的申请。这里,我们报导那锂(李) ,药过去常对待心情混乱,极大地从老鼠提高 iPSC 产生胚胎的成纤维细胞和人的脐的静脉 endothelial 房间。李与(Oct4 ) 或二个因素(OS 或好) 便于 iPSC 产生。支持 reprogramming 上的李的效果仅仅部分取决于它的主要目标 GSK3β。不同于另外的 GSK3β禁止者,李不仅增加 Nanog 的表示,而且提高 Nanog 的 transcriptional 活动。我们也发现李由经由 LSD1 的 downregulation 支持 epigenetic 修正施加它的效果, H3K4 特定的 histone demethylase。将 LSD1 击倒部分在提高 reprogramming 模仿李的效果。我们的结果不仅提供一个直接方法改进 iPSC 产生效率,而且为体的房间 reprogramming 作为一个批评调节的人识别了 histone demethylase。 | Quan Wang Xinxiu Xu Jun Li Jing Liu Haifeng Gu Ru Zhang Jiekai Chen Yin Kuang Jian Fei Cong Jiang Ping Wang Duanqing Pei Sheng Ding Xin Xie | 2011 | Cell Research2011,21,10: | 23 |
| 2 | Gene expression of hepatocyte growth factor and its receptor in HCC and nontumorous liver tissues显示文摘METHODSGeneexpressionofHGFandHGFrin26casesofHCCtissueandtheiradjacentnontumorouslivertissueswasdeterminedwithdigoxigeninla... | LUO Yun Quan, WU Meng Chao and CONG Wen Ming | 1999 | World Journal of Gastroenterology1999,5,2: | 17 |
| 3 | The Impacts of Mosquito Density and Meteorological Factors on Dengue Fever Epidemics in Guangzhou, China, 2006-2014: a Time-series Analysis显示文摘Objective To explore the associations between the monthly number of dengue fever(DF) cases and possible risk factors in Guangzhou, a subtropical city of China. Methods The monthly number of DF cases, Breteau Index(BI), and meteorological measures during 2006-2014 recorded in Guangzhou, China, were assessed. A negative binomial regression model was used to evaluate the relationships between BI, meteorological factors, and the monthly number of DF cases. Results A total of 39,697 DF cases were detected in Guangzhou during the study period. DF incidence presented an obvious seasonal pattern, with most cases occurring from June to November. The current month's BI, average temperature(Tave), previous month's minimum temperature(Tmin), and Tave were positively associated with DF incidence. A threshold of 18.25 °C was found in the relationship between the current month's Tmin and DF incidence. Conclusion Mosquito density, Tave, and Tmin play a critical role in DF transmission in Guangzhou. These findings could be useful in the development of a DF early warning system and assist in effective control and prevention strategies in the DF epidemic. | SHEN Ji Chuan LUO Lei LI Li JING Qin Long OU Chun Quan YANG Zhi Cong CHEN Xiao Guang | 2015 | Biomedical and Environmental Sciences2015,28,5: | 12 |
| 4 | Laparoscopic distal pancreatectomy with or without splenectomy: spleen-preservation does not increase morbidity显示文摘BACKGROUND: The indications for laparoscopic spleen-preserving distal pancreatectomy (LSPDP) and its morbidity compared with laparoscopic distal pancreatectomy with splenectomy (LDPS) are ill-defined. This study aimed to share the indications for spleen-preservation and investigate the safety and outcome of LSPDP at our institution. METHODS: A retrospective review of patients who were scheduled to receive laparoscopic surgery for distal pancreatic lesions was conducted. The indications, surgical procedures, intra-operative data, and outcomes of the two procedures were collected and compared by statistical analysis. RESULTS: LDPS and LSPDP were successfully performed in 16 and 21 patients respectively, whereas they were converted to open surgery in 9 patients. There were no significant differences in age, gender, operation time, blood loss, and conversion rate between the LDPS and LSPDP groups. The mean tumor size showed an inter-group difference (5.05 vs 2.53 cm, P<0.001). There were no significant differences in complication and morbidity rates between the two groups. All patients remained alive without recurrence during a follow-up of 9 to 67 months (median 35).CONCLUSION: LSPDP has a morbidity and outcome comparable to LDPS. | Yu-Pei Zhao, Xiao Du, Meng-Hua Dai, Tai-Ping Zhang, Quan Liao, Jun-Chao Guo, Lin Cong ,Ge Chen Department of General Surgery, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730, China | 2012 | Hepatobiliary & Pancreatic Diseases International2012,11,5: | 8 |
| 5 | Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis显示文摘Curcumenol,an effective ingredient of Wenyujin,has been reported that exerted its antitumor potential in a few cancer types.However,the effect and molecular mechanism of curcumenol in lung cancer are largely unknown.Here,we found that curcumenol induced cell death and suppressed cell proliferation in lung cancer cells.Next,we demonstrated that ferroptosis was the predominant method that contributed to curcumenol-induced cell death of lung cancer in vitro and vivo for the first time.Subsequently,using RNA sequencing,we found that the long non-coding RNA H19(lncRNA H19)was significantly downregulated in lung cancer cells treated with curcumenol,when compared to untreated controls.Overexpression of lncRNA H19 eliminated the anticancer effect of curcumenol,while lncRNA H19 knockdown promoted ferroptosis induced by curcumenol treatment.Mechanistically,we showed that lncRNA H19 functioned as a competing endogenous RNA to bind to miR-19b-3p,thereby enhanced the transcription activity of its endogenous target,ferritin heavy chain 1(FTH1),a marker of ferroptosis.In conclusion,our data show that the natural product curcumenol exerted its antitumor effects on lung cancer by triggering ferroptosis,and the lncRNA H19/miR-19b-3p/FTH1 axis plays an essential role in curcumenol-induced ferroptotic cell death.Therefore,our findings will hopefully provide a valuable drug for treating lung cancer patients. | Ruonan Zhang Ting Pan Yu Xiang Mingming Zhang Han Xie Zimao Liang Bi Chen Cong Xu Jing Wang Xingxing Huang Qianru Zhu Ziming Zhao Quan Gao Chengyong Wen Wencheng Liu Weirui Ma Jiao Feng Xueni Sun Ting Duan Elaine Lai-Han Leung Tian Xie Qibiao Wu Xinbing Sui | 2022 | Bioactive Materials2022,7,7: | 8 |
| 6 | Micrometastasis in surrounding liver and the minimal length of resection margin of primary liver cancer显示文摘AIM: To describe the distribution of micrometastases in the surrounding liver of patients with primary liver cancer (PLC), and to describe the minimal length of resection margin (RM) for hepatectomy.METHODS: From November 2001 to March 2003, 120 histologically verfied PLC patients without macroscopic tumor thrombi or macrosatellites or extrahepatic metastases underwent curative hepatectomy. Six hundreds and twenty-nine routine pathological sections from these patients were re-examined retrospectively by light microscopy. In the prospective study, curative hepatectomy was performed from November 2001 to March 2003 for 76 histologically verfied PLC patients without definite macroscopic tumor thrombi or macrosatellites or extrahepatic metastases in preoperative imaging. Six hundreds and forty-five pathological sections from these patients were examined by light microscopy. The resected liver specimens were minutely examined to measure the resection margin and to detect the number of daughter tumor nodules, dominant lesions, and macroscopic tumor thrombi inside the lumens of the major venous system. The paraffin sections were microscopically examined to detect the microsatellites, microscopic tumor thrombi, fibrosis tumor capsules, as well as capsule invasion and the distance of histological spread of the micrometastases.RESULTS: In the retrospective study, 70 micrometastases were found in surrounding liver in 26 of the 120cases (21.7%). The farthest distance of histological micrometastasis was 3.5 mm, 5.3 mm and 6.0 mm in 95%, 99% and 100% cases, respectively. Macroscopic tumor thrombi or macrosatellites were observed in 18 of 76 cases, and 149 micrometastases were found in the surrounding live in 25 (43.1%) of 58 cases with no macroscopic tumor thrombi. The farthest distance of histological micrometastasis was 4.5 mm, 5.5 mm and 6.0 mm in 95%, 99% and 100% cases, respectively. Two hundred and sixty-seven micrometastases were found in surrounding liver in 14 (77.8%) out of 18 cases with macroscopic tumor thrombi or macrosatellites. The farthest distance of histological micrometastasis was 18.5 mm, 18.5 mm and 19.0 mm in 95%, 99% and 100% cases, respectively.CONCLUSION: The required minimal length of RM is 5.5 mm and 6 mm respectively to achieve 99% and 100% micrometastasis clearance in surrounding liver of PLC patients without macroscopic tumor thrombi or macrosatellites, and should be greater than 18.5 mm to obtain 99% micrometastasis clearance in surrounding liver of patients with macroscopic tumor thrombi or macrosatellites. | Xue-Ping Zhou Zhi-Wei Quan Wen-Ming Cong Ning Yang Hai-Bin Zhang Shu-Hui Zhang Guang-Shun Yang | 2007 | World Journal of Gastroenterology2007,13,33: | 7 |
| 7 | Impact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice显示文摘 | Fan FAN Quan CAO Cong WANG Xin MA Cheng SHEN Xiang-wei LIU Li-ping BU Yun-zeng ZOU Kai HU Ai-jun SUN Jun-bo GE | 2014 | Acta Pharmacologica Sinica2014,35,8: | 5 |
| 8 | Polarization-independent all-silicon dielectric metasurfaces in the terahertz regime显示文摘Dielectric metasurfaces have achieved great success in realizing high-efficiency wavefront control in the optical and infrared ranges. Here, we experimentally demonstrate several efficient, polarization-independent, all-silicon dielectric metasurfaces in the terahertz regime. The metasurfaces are composed of cylindrical silicon pillars on a silicon substrate, which can be easily fabricated using etching technology for semiconductors. By locally tailoring the diameter of the pillars, full control over abrupt phase changes can be achieved. To show the controlling ability of the metasurfaces, an anomalous deflector, three Bessel beam generators, and three vortex beam generators are fabricated and characterized. We also show that the proposed metasurfaces can be easily combined to form composite devices with extended functionalities. The proposed controlling method has promising applications in developing low-loss, ultra-compact spatial terahertz modulation devices. | HUIFANG ZHANG XUEQIAN ZHANG QUAN XU QIU WANG YUEHONG XU MINGGUI WEI YANFENG LI JIANQIANG GU ZHEN TIAN CHUNMEI OUYANG XIXIANG ZHANG CONG HU JIAGUANG HAN WEILI ZHANG | 2018 | Photonics Research2018,9,1: | 4 |
| 9 | Risk factors for postoperative pancreatic fistula in patients with insulinomas:analysis of 292 consecutive cases显示文摘BACKGROUND:Pancreatic fistula (PF) remains the most challenging complication in pancreatic surgery,yet few published studies have focused on the risk factors for postoperative PF in patients undergoing surgery for insulinomas.METHODS:From January 1990 to February 2010,a total of 292 patients with insulinomas underwent surgery at Peking Union Medical College Hospital.Demographic data,intraoperative procedures,and postoperative data were collected.Particular attention was paid to variables associated with PF as defined by the International Study Group of Pancreatic Fistula (ISGPF).Univariate and multivariate analyses were used to identify possible risk factors for PF.RESULTS:PF was found in 132 (45.2%) patients,of whom 90 were classified into ISGPF grade A,33 grade B,and 9 grade C.Multivariate analysis showed that male patients (OR=2.56;P=0.007) and operative time >180minutes (OR=3.756;P<0.0001) were independent risk factors for clinical PF.Pancreatic resection with stapler was a protective factor for both total PF (OR=0.022;P=0.010) and clinical PF (OR=0.097;P=0.007).CONCLUSIONS:Male gender and operative time >180minutes were independent risk factors for clinical PF,while pancreatic resection with a stapler was a protective factor.Whether body mass index (BMI) and other variables during operation are risk factors of PF needs further study. | Zhao, Yu-Pei Zhan, Han-Xiang Cong, Lin Zhang, Tai-Ping Liao, Quan Dai, Meng-Hua Cai, Li-Xing Zhu, Yu | 2012 | Hepatobiliary & Pancreatic Diseases International2012,11,1: | 3 |
| 10 | Controlling disorder in host lattice by hetero-valence ion doping to manipulate luminescence in spinel solid solution phosphors显示文摘Phosphor materials have been rapidly developed in the past decades. Developing phosphors with desired properties including strong luminescence intensity and long lifetime has attracted widespread attention. Herein, we show that hetero-valence ion doping can serve as a potent strategy to manipulate luminescence in persistent phosphors by controlling disorder in the host lattice. Specifically, spinel phosphor Zn(Ga_(1-x)Zn_x)(Ga_(1-x)Ge_x)O_4:Cr is developed by doping ZnGa_2O_4:Cr with tetravalent Ge^(^(4+)).Compared to the original ZnGa_2O_4:Cr, the doped Zn(Ga_(1-x)Zn_x)(Ga_(1-x)Ge_x)O_4:Cr possesses significantly enhanced persistent luminescence intensity and prolonged decay time. Rietveld refinements show that Ge^(4+)enters into octahedral sites to substitute Ga^(3+), which leads to the co-substitution of Ga^(3+) by Zn^(2+) for charge compensation. The hetero-valence substitution of Ga^(3+) by Ge^(4+)and Zn^(2+) enriches the charged defects in Zn(Ga_(1-x)Zn_x)(Ga_(1-x)Ge_x)O_4:Cr, making it possible to trap large amounts of charge carriers within the defects during excitation. Electron paramagnetic resonance measurement further confirms that the amount of Cr^(3+) neighboring charged defects increases with Ge^(4+)doping. Thus charge carriers released from defects can readily combine with the neighboring Cr^(3+) to produce bright persistent luminescence after excitation ceases. The hetero-valence ion doping strategy can further be employed to develop many other phosphors and contributes to lighting, photocatalysis and bioimaging. | Qinqin Ma Jie Wang Wei Zheng Qian Wang Zhiheng Li Hengjiang Cong Huijun Liu Xueyuan Chen Quan Yuan | 2018 | Science China Chemistry2018,61,12: | 3 |
| 11 | Gastroesophageal Varices (Bleeding) and Splenomegaly: The Initial Manifestations of Some Pancreatic Body and Tail Carcinoma显示文摘INTRODUCTION The most common symptoms of the pancreatic body and tail carcinoma are epigastric pain,asthenia and back pain.However,these symptoms are nonspecific,which as a consequence leads to late diagnosis as well as a low resection rate between 10% and 30%,with a 5 years overall survival rate below 10%.[1] That how to increase early diagnosis of the pancreatic body and tail carcinoma has been a difficult problem since then.Sometimes the pancreatic body and tail carcinoma can induce splenic vein occlusion,leading to pancreatic sinistral portal hypertension (PSPH).PSPH is defined as a pathological condition of splanchnic venous hypertension localized within the left-sided gastrosplenic region in pancreatic diseases. | Xiao-Bin Li Luo Zhao Quan Liao Qiang Xu Tai-Ping Zhang Lin Cong Bing Mu | 2015 | Chinese Medical Journal2015,,4: | 3 |
| 12 | Extension Protocol for the Investigation on Nutrition Status and Clinical Outcome of Patients with Common Cancers in China(INSCOC)Study:2021 update显示文摘Background Malnutrition is common in patients with cancer,and this adversely affects the survival and quality of life of patients.Chinese Society for Nutritional Oncology issued a multi-center,large-scale,long-term follow-up prospective study,the Investigation on Nutrition Status and Clinical Outcome of Patients with Common Cancers in China(INSCOC study)since 2013.This is an extension to the previous 2013-2020 study protocol.This study still sought to:①address the prognostic impact of nutritional factors and quality of life on cancer patient survival;②describe the overall and cancer-specific incidence and/or distribution of malnutrition and different measurements of patient quality of life.Methods and study design This is an observational,multi-centered,hospital-based prospective cohort study.Data collection will be performed at baseline(within 48 hours after patient admission),during the hospital stay and 30 days after hospital admission.Follow-up will be conducted for 1-20 years after enrollment.The primary outcome will be the all-cause mortality/overall survival,and secondary outcomes will be the length of hospital stay and costs of hospitalization.Study factors will include demographic characteristics,tumor characteristics,information about chronic diseases,hematological measurements(e.g.,red blood cell count,total lymphocyte counts,hemoglobin,albumin,prealbumin,creatinine,C-reactive protein,IL-6),anthropometric measurements(e.g.,height,weight,arm circumference,arm muscle circumference,triceps skinfold thickness,and waist circumference),body composition parameters,PG-SGA scores,quality of life(as indicated by the QLQ-C30 questionnaire),muscle mass(as indicated by the calf circumference),muscle strength(as indicated by the handgrip strength),muscle function(as indicated by the six-meter walking speed test)and physical status assessments(as indicated by the Karnofsky Performance Status scores).This clinical study protocol was approved by local Ethics Committees of all the participating hospitals.Written informed consent is required for each subject included.Discussion This multi-center,large-scale,long-term follow up prospective study will help improve the diagnosis of malnutrition in cancer patients and identify the risk factors associated with adverse clinical outcomes.The anticipated results of this study will highlight the need for a truly scientific appraisal of nutrition therapy in Chinese oncology populations,and finally help treat the potentially reversible elements of malnutrition in cancer patients to improve their clinical outcomes in the future. | Hong Xia Xu Chun Hua Song Liang Yu Yin Chang Wang Zhen Ming Fu Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Fu Xiang Zhou Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Zhi Kang Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Xiang Hua Wu Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Min Weng Qing Hua Yao Ya Yin Yu Quan Jun Lyu Hong Qiu Ming Liu Wei Li Han Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group | 2022 | Journal of Nutritional Oncology2022,7,2: | 3 |
| 13 | Experimental study on ageing characteristics of electric locomotive ethylene propylene rubber cable under mechanical-thermal combined action显示文摘The train-mounted ethylene propylene rubber(EPR)cables of electric locomotive are partly restricted by the body structure and spatial layout and are in a combined envi-ronment of strong mechanical bending and thermal ageing.The degradation character-istics of the insulation layer have not yet received sufficient attention.In order to study the ageing characteristics of EPR cables of electric locomotive under the combined action of machine and thermal,this paper designs a bending-thermal combined ageing test platform for cables with a temperature of 135°C,bending diameter of 393.52 mm,590.28 mm and unbending cables,and tests after ageing.The product has been tested by infrared spectroscopy,scanning electron microscopy,elongation at break and broadband dielectric spectroscopy.The research results show that the bending outer part of the train-mounted EPR cable is a pain point.Under the combined action of bending and thermal,whether it is microstructure or macro performance,the degradation rate and degree of the bending of outer insulation layer are greater than the value under a single thermal ageing condition.Mechanical bending has an accelerating effect on the ageing of the EPR insulation layer.The research results can provide a reference for the ageing characteristics of the train-mounted EPR cable under the bending-thermal synergy and the evaluation of operating state of the train-mounted EPR cable under bending-thermal operating conditions. | Lijun Zhou Cong Liu Shengwei Quan Xiangyu Zhang Dongyang Wang | 2022 | High Voltage2022,7,4: | 3 |
| 14 | Pterygial body epithelium domination of pterygial proliferation with TCF4 as a potential key factor显示文摘AIM: To characterize the proliferative capacity of pterygial epithelium in different regions(head, neck and body) of pterygium and explore the function of transcription factor 4(TCF4) in pterygium proliferation.METHODS: Thirty pterygium tissues and 10 normal conjunctival tissues were obtained from Zhongshan Ophthalmic Center(ZOC) and Guangdong Eye Bank, respectively. Proliferative capacity of head, neck and body in pterygial epithelium was measured using clonal analysis, fold growth analysis and expression profile of proliferative markers revealed by immunofluorescent staining and real-time PCR. The expression of TCF4 was highlighted by double immunofluorescent staining with other proliferation related markers such as proliferating cell nuclear antigen(PCNA) and ATP-binding cassette subfamily G member 2(ABCG2).RESULTS: The proliferative potential of pterygial epithelium was higher than that of normal conjunctival epithelium. High expression levels of proliferative markers(P63α, PCNA and ABCG2) in pterygial body epithelium were observed in immunofluorescent staining and real-time PCR(P<0.05). Also, epithelial cells isolated from pterygial body demonstrated higher proliferative capacity in clonal analysis and fold growth analysis, than those isolated from the head and neck regions. The TCF4 expression in pterygial epithelium was similar to other proliferative markers(P63α, PCNA and ABCG2), as higher in pterygial body than head and neck. Moreover, TCF4 showed coexpression with other proliferation-related markers(PCNA and ABCG2) in the double immunofluorescent staining experiment.CONCLUSION: The proliferative capacity in pterygial body epithelium is prominent than the head and neck regions, and upregulated TCF4 may be associated with enhanced proliferation in the pterygium. | Cong Nie Xin-Chun Zhang Si-Ying Xu Ya-Dan Quan Zhi-Xin Tang Rong Lu | 2018 | International Journal of Ophthalmology(English edition)2018,11,9: | 2 |
| 15 | Control Strategy of a Two-Lap Connection Converter显示文摘Two-lap sequential control converters are usually adopted to supply and improve the power factor of input side. The line harmonic damage generated by a sequential control thyristor converter can be serious. To solve this prob-lem and seek an optimum control strategy,we derived the changeable regular of the line-input-current,the fundamen-tal-frequency-current,the harmonic-current-content and the harmonic total distortion ratio of the converter at different firing angles. We obtained relevant data from experiments with a sequential control system of a DC 2.2kW/220V motor. With the example of the operating condition of a DC mine elevator,the harmonic current is two times approximately in sequential control compared to synchronous control when the firing angle of the two converters differs in 30°. At dif-ferent operating states of a two-lap connection converter,the ideal strategy is an exchange between sequential control and synchronous control,by which we can achieve the complementary goal of improving the power factor and har-monic effect. All analytical conclusions are supported by simulation and experimental results. | QUAN Ji-nan WANG Cong | 2007 | Journal of China University of Mining and Technology2007,17,3: | 2 |
| 16 | Synthesis and Characterization of the Polyacrylonitrile-block- poly(methyl acrylate) by RAFT Technique显示文摘Polyacrylonitrile-block-poly(methyl acrylate)(P(AN-b-MA)) was synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization employing macro-RAFT agent (PAN-RAFT) as the chain transfer agent and azobis(isobutyronitrile) (AIBN) as the initiator. A linear relationship between ln([M]0/[M]t) and reaction time was observed. The molecular structure of P(AN-b-MA) was characterized by 1H-NMR, element analysis, FTIR and SEC. The molecular weight distribution (MWD) was less than 1.40, the Mn could be controled from 0.733 to 4.834×104, and the molar content of MA in P(AN-b-MA) were from 15.6 to 75.0 percentage, respectively. | Quan Fu AN Jin Wen QIAN Cong Jie GAO | 2006 | Chinese Chemical Letters2006,17,3: | 2 |
| 17 | Clinical Characters of Gastrointestinal Lesions in Intestinal Behcet's Disease显示文摘Objective To investigate the clinical features,diagnosis methods,therapeutic principles of intestinal Behcet's disease.Methods The clinical data of 45 patients with confirmed intestinal Behcet's disease admitted to Peking Union Medical College Hospital from August 1998 to April 2010 were retrospectively analyzed.Results The clinical courses of patients with intestinal Behcet's disease were from 26 days to 33 years,and the average duration was 6.32±1.01 years.The appearance of extra-gastrointestinal symptoms was significantly earlier than that of gastrointestinal symptoms(7.35±1.39 years vs.3.24±0.82 years,P<0.05).The predominant gastrointestinal manifestations were right lower quadrant pain(95.56%) and hematochezia or melena(40.00%).Misdiagnosis occurred in 17 cases.In patients without systemic medicine therapy before surgery,the incidence of postoperative infection of incision site and abdominal cavity was significantly higher than that in those undergoing systemic medicine therapy(80.00% vs.0%,P<0.05).Conclusions Because of the diversity of gastrointestinal manifestations,intestinal Behcet's disease is easily misdiagnosed.The systemic medical therapy before surgery could decrease the incidence of infection of incision and abdominal cavity. | Wei-bin Wang Yu-pei Zhao Lin Cong Hao Jing Quan Liao Tai-ping Zhang | 2011 | Chinese Medical Sciences Journal2011,26,3: | 2 |
| 18 | Enhanced heterogeneous Fenton-like activity by Cu-dopecl BiFeO3 perovskite for degradation of organic pollutants显示文摘Heterogeneous Fenton-like reaction has been extensively investigated to eliminate refractory organic contaminants in wastewater,but it usually shows low catalytic performance due to difficulty in reduction from Fe(Ⅲ)to Fe(Ⅱ).In this study,enhanced catalytic efficiency was obtained by employing Cu-doped BiFeO3 as heterogeneous Fenton-like catalysts,which exhibited higher catalytic perfor;nance toward the activation of H2O2 for phenol degradation than un-doped BiFeO3.. BiFe0.8Cu0.2O3 displayed the best performance,which yielded 91% removal of phenol (10mg L^-1) in 120min.The pseudo first-order kinetic rate constant of phenol degradation in BiFe0.8Cu0.2O3 catalyzed heterogeneous Fenton-like reaction was 5times higher than those of traditional heterogeneous Fenton-like catalysts,such as Fe3O4 and goethite.The phenol degradation efficiency could still reach 83% after 4 cycles,which implied the good stability of BiFe0.8Cu0.2O3.The high catalytic activity of BiFe0.8Cu0.2O3 was attributed to the fact that the doping Cu into BiFeO3 could promote the generation of Fe(Ⅱ)in the catalyst and then facilitate the activation of H2O2 to degrade the organic pollutants. | Jie Mao Xie Quan Jing Wang Cong Gao Shuo Chen Hongtao Yu Yaobin Zhang | 2018 | Frontiers of Environmental Science & Engineering2018,12,6: | 2 |
| 19 | Carbon nanotubes-incorporated MIL-88B-Fe as highly efficient Fenton-like catalyst for degradation of organic pollutants显示文摘Iron-based metal organic frameworks have been verified to be efficient heterogeneous Fenton catalysts due to their open pore channels and highly uniform distribution of metallic centers.In these catalysts,however,the iron element is mainly in the form of Fe(III),which results in a process required to reduce Fe(III)to Fe(II)to initiate Fenton reaction.To address this problem,carbon nanotubes(CNTs)with electron-rich oxygen-functional groups on the surface were incorporated into the metal organic frameworks(MIL-88B-Fe)to improve Fe(II)content for an enhanced Fenton-like performance.The prepared CNT@MIL-88B-Fe(C@M)showed much stronger catalytic ability toward H2O2 than MIL-88B-Fe.The pseudo-first-order kinetic constant for phenol degradation by C@M(0.32 min–1)was about 7 times that of MIL-88B-Fe,and even higher than or comparable to the values of reported heterogeneous Fenton-like catalysts.Moreover,the Fenton-like system could effectively degrade various kinds of refractory organic pollutants and exhibited excellent catalytic activity over a wide pH range(4–9).XPS analysis confirmed that Fe(II)content of the catalyst gradually increased with CNT loadings.Electron spin resonance analysis showed that the signal intensity(?OH)of C@M was much higher than MIL-88B-Fe,which was consistent with the degradation efficiency of pollutants.Furthermore,the Fe(II)content of the catalyst gradually increased along with the oxygen-functional group content of CNTs.The result demonstrated that oxygen-containing functional groups of CNTs have a significant impact on the enhanced catalytic performance of C@M.This study provides a new insight to enhance Fenton reaction by using nanocarbon materials. | Hang Zhang Shuo Chen Haiguang Zhang Xinfei Fan Cong Gao Hongtao Yu Xie Quan | 2019 | Frontiers of Environmental Science & Engineering2019,13,2: | 2 |
| 20 | Broadband terahertz rotator with an all-dielectric metasurface显示文摘Polarization manipulation is essential in developing cutting-edge photonic devices ranging from optical communication displays to solar energy harvesting. Most previous works for efficient polarization control cannot avoid utilizing metallic components that inevitably suffer from large ohmic loss and thus low operational efficiency.Replacing metallic components with Mie resonance-based dielectric resonators will largely suppress the ohmic loss toward high-efficiency metamaterial devices. Here, we propose an efficient approach for broadband, highquality polarization rotation operating in transmission mode with all-dielectric metamaterials in the terahertz regime. By separating the orthogonal polarization components in space, we obtain rotated output waves with a conversion efficiency of 67.5%. The proposed polarization manipulation strategy shows impressive robustness and flexibility in designing metadevices of both linear-and circular-polarization incidences. | QUANLONG YANG XIEYU CHEN QUAN XU CHUNXIU TIAN YUEHONG XU LONGQING CONG XUEQIAN ZHANG YANFENG LI CAIHONG ZHANG XIXIANG ZHANG JIAGUANG HAN WEILI ZHANG | 2018 | Photonics Research2018,,11: | 2 |