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| 1 | Experimental Study of the Effect of Autonomic Nervous System on the Transmural Dispersion of Ventricular Repolarization under Acute Myocardial Ischemia in Vivo显示文摘Summary: The effect of the autonomic nerves on the transmural dispersion of ventricular repolarization (TDR) under acute myocardial ischemia in intact canine was investigated. Using the monophasic action potential (MAP) recording technique, MAPs of the epicardium (Epi), midmyocardium (Mid) and endocardium (Endo) were recorded simultaneously by specially designed plunge-needle electrodes at the left ventricular free wall under acute myocardial ischemia in 12 open-chest dogs. MAPD 90 and TDR among three myocardial layers as well as the incidence of the early afterdepolarization (EAD) before autonomic nervous stimulation and during autonomic nervous stimulation were compared. It was found that 10 min after acute myocardial ischemia, TDR was increased from 55±8 ms to 86±15 ms during sympathetic stimulation (P<0.01). The TDR (53±9 ms) during parasympathetic stimulation was not significantly different from that of the control (55±8 ms) (P>0.05). The EAD was elicited in the Mid of 2 dogs (16 %) 10 min after acute myocardial ischemia, but the EAD were elicited in the Mid of 7 dogs (58 %) during sympathetic stimulation (P<0.01). It was concluded that: (1) Sympathetic stimulation can increase the transmural dispersion of repolari-zation and induce early afterdepolarizations in the Mid under acute myocardial ischemia, which provide the opportunity for the ventricular arrhythmia developing; (2) Parasympathetic stimulation has no significant effect on the transmural dispersion of repolarization under myocardial ischemia. | ZHANG Cuntai(张存泰) XU Dawen(徐大文) LI Yang(李泱) LIU Nian(刘念) ZHONG Jianghua(钟江华) WANG Lin(王琳) LU Zaiying(陆再英) | 2002 | Journal of Huazhong University of Science and Technology(Medical Sciences)2002，22，2： | 2 |
| 2 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 3 | Bayesian lear- ning for spatial filtering in an EECr-based brain-computer inter- face 显示文摘 | Zhang Haihong Yang Huijuan Guan Cuntai | 2013 | Neural Networks and Learning Systems2013，24，7： | 1 |
| 4 | Optimizing the channel selection and classification accuracy in EEG-based BCI 显示文摘 | ARVANEH M GUAN Cuntai ANG K K | 2011 | IEEE Trans Biomed Eng2011，58，6： | 1 |
| 5 | Effect of oxidative stress on ventricular arrhythmia in rabbits with adriamycin-induced cardiomyopathy显示文摘 | Li He Jianmin Xiao Hui Fu Guangsheng Du Xing Xiao Cuntai Zhang Ye Gu Yexin Ma | 2012 | Journal of Huazhong University of Science and Technology2012，，3： | 1 |
| 6 | Resting state changes in functional connectivity correlate with movement recovery for BCI and robot assisted upper-extremity training after stroke显示文摘 | Bdlint V Cuntai G Pan YZ | 2013 | Neurorehabil Neural Repair2013，27，1： | 1 |
| 7 | Controlling a wheelchair indoors using thought显示文摘 | Rebsamen B Burdet E Guan Cuntai | | 0，，02： | 1 |
| 8 | Robust classification of EEG signal for brain-computer interface显示文摘 | Thulasidas Manoj Guan Cuntai Wu Jiankang | 2006 | IEEE Transactions on Neural Systems and Rehabilitation Engineering2006，14，1： | 1 |
| 9 | Temporal classification of multichannel near-infrared spectroscope signals of motor imagery for developing a brain-computer interlace显示文摘 | Ranganatha S Haihong Z Cuntai G | 2007 | NeuroImage2007，34，4： | 1 |
| 10 | A self-training semi-supervised support vector machine algorithm and its applications in brain computer interface显示文摘 | Li Yuanqing Li Huiqi Guan Cuntai | 2007 | IEEE Transactions on Multimedia2007，28，1： | 1 |
| 11 | Optimi- zing the channel selection and classification accuracy in EEG- based BCI 显示文摘 | ARVANEH M CUNTAI G and KAI K A | 2011 | IEEE Transactions on Biomedical Engineer- ing2011，58，6： | 1 |
| 12 | Regularizing Common Spatial Patterns to Improve BCI Designs:Unified Theory and New Algorithms显示文摘 | Lotte F Guan Cuntai | 2011 | IEEE Transactions on Biomedical Engineering2011，58，2： | 1 |
| 13 | Probability estimation for recoverability analysis of blind source separation based on sparse representation显示文摘 | Y Q Li S I Amari A Cichocki Guan Cuntai | 2006 | IEEE Transactions on Information Theory2006，52，7： | 1 |
| 14 | A Self-training Semi-supervised SVM Algorithm and Its Application in an EEG-based Brain Computer Interface Speller System显示文摘 | LI Yuanqing GUAN Cuntai LI Huiqi | 2008 | Pattern Recognition Letters2008，29，9： | 1 |
| 15 | A Self- training Semi-supervised SVM Algorithm and Its Application in an EEC,-based-Brain Computer Interface Speller System 显示文摘 | Li Yuanqing Guan Cuntai Li Huiqi | 2008 | Pattern Recognition Letters2008，，29： | 1 |
| 16 | Regularizing common spatial pat- terns to improve BCI designs: unified theory and new algorithms 显示文摘 | LOTTE F GUAN Cuntai | 2011 | IEEE Trans Biomed Eng2011，58，2： | 1 |
| 17 | Detection of motor imagery of swallow EEG signals based on the dual-tree complex wavelet transform and adaptive model selection显示文摘 | Huijuan Yang Cuntai Guan Karen Sui Geok Chua See San Chok Chuan Chu Wang Phua Kok Soon Christina Ka Yin Tang Kai Keng Ang | 2014 | Journal of Neural Engineering2014，，3： | 1 |
| 18 | Asyn- chronous P300-Based brain putational approach with Transactions on Biomedical computer interfaces: a com- statistical models显示文摘 | Zhang Haihong Guan Cuntai Wang Chuanchu | 2008 | IEEE Engineering2008，55，6： | 1 |
| 19 | Regularized common spatial pattern with aggregation for EEG classifica- tion in small-sample setting 显示文摘 | LU Haiping ENG H L GUAN Cuntai | 2010 | IEEE Trans Biomed Eng2010，57，12： | 1 |
| 20 | A selftraining semi-supervised SVM algorithm and its application in an EEG-based brain computer interface speller system显示文摘 | LI Yuanqing GUAN Cuntai LI Huiqi | 2008 | Pattern Recognition Letters2008，29，9： | 1 |
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