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| 1 | Evolutionary decision-makings for the dynamic weapon-target assignment problem显示文摘The dynamic weapon-target assignment (DWTA) problem is an important issue in the field of military command and control. An asset-based DWTA optimization model was proposed with four kinds of constraints considered, including capability constraints, strategy constraints, resource constraints and engagement feasibility constraints. A general 'virtual' representation of decisions was presented to facilitate the generation of feasible decisions. The representation is in essence the permutation of all assignment pairs. A construction procedure converts the permutations into real feasible decisions. In order to solve this problem, three evolutionary decision-making algorithms, including a genetic algorithm and two memetic algorithms, were developed. Experimental results show that the memetic algorithm based on greedy local search can generate obviously better DWTA decisions, especially for large-scale problems, than the genetic algorithm and the memetic algorithm based on steepest local search. | CHEN Jie1,2, XIN Bin1,2, PENG ZhiHong1,2, DOU LiHua1,2 & ZHANG Juan1,2 1 School of Automation, Beijing Institute of Technology, Beijing 100081, China 2 Key Laboratory of Complex System Intelligent Control and Decision, Ministry of Education, Beijing 100081, China | 2009 | Science in China(Series F)2009，52，11： | 19 |
| 2 | Randomized controlled trial: Moxibustion and acupuncture for the treatment of Crohn's disease显示文摘AIM: To evaluate the clinical efficacy and safety of acupuncture and moxibustion for the treatment of active Crohn's disease(CD).METHODS: Ninety-two patients were equally and randomly divided into the treatment group and received herb-partitioned moxibustion combined with acupuncture, and the control group received wheat bran-partitioned moxibustion combined with superficial acupuncture. The patients received three treatment sessions per week for 12 wk and were followed up for 24 wk. The main outcome was evaluated using the CD Activity Index(CDAI) score, and the secondary outcomes were evaluated using laboratory indicators such as hemoglobin(HGB), C-reactive protein(CRP), erythrocyte sedimentation rate, quality-of-life, endoscopic ratings, and intestinal histology scores.RESULTS: The CDAI scores of both the treatment and control groups were significantly reduced after treatment compared with those measured before treatment. However, the degree of improvement in the treatment group was significantly greater than that of the control group. The improvement in symptoms in patients of the treatment group was sustained at follow-up, whereas that of the control group was not. The overall efficacy of the treatment was significantly greater than that of the control. Both groups demonstrated significant improvements in quality-of-life ratings after treatment, but the improvement was significantly greater in the treatment group than in the control group. In addition, the patients in the treatment group showed significantly increased HGB and significantly decreasedCRP levels and histopathological scores at the end of treatment, whereas the control group did not exhibit significant changes.CONCLUSION: Moxibustion with acupuncture provided significant therapeutic benefits in patients with active CD beyond the placebo effect and is therefore an effective and safe treatment for active CD. | Chun-Hui Bao Ji-Meng Zhao Hui-Rong Liu Yuan Lu Yi-Fang Zhu Yin Shi Zhi-Jun Weng Hui Feng Xin Guan Jing Li Wei-Feng Chen Lu-Yi Wu Xiao-Ming Jin Chuan-Zi Dou Huan-Gan Wu | 2014 | World Journal of Gastroenterology2014，20，31： | 19 |
| 3 | A joint mid-course and terminal course cooperative guidance law for multi-missile salvo attack显示文摘Salvo attacking a surface target by multiple missiles is an effective tactic to enhance the lethality and penetrate the defense system. However, existing cooperative guidance laws in the midcourse or terminal course are not suitable for long-and medium-range missiles or stand-off attacking. Because the initial conditions of cooperative terminal guidance that are generally generated from the mid-course flight may not lead to a successful cooperative terminal guidance without proper mid-course flight adjustment. Meanwhile, cooperative guidance in the mid-course cannot solely guarantee the accuracy of a simultaneous arrival of multiple missiles. Therefore, a joint mid-course and terminal course cooperative guidance law is developed. By building a distinct leader-follower framework, this paper proposes an efficient coordinated Dubins path planning method to synchronize the arrival time of all engaged missiles in the mid-course flight. The planned flight can generate proper initial conditions for cooperative terminal guidance, and also benefit an earliest simultaneous arrival. In the terminal course, an existing cooperative proportional navigation guidance law guides all the engaged missiles to arrive at a target accurately and simultaneously.The integrated guidance law for an intuitive application is summarized. Simulations demonstrate that the proposed method can generate fast and accurate salvo attack. | Jie ZENG Lihua DOU Bin XIN | 2018 | Chinese Journal of Aeronautics2018，31，6： | 12 |
| 4 | Cyclic adenosine monophosphate signal pathway in targeted therapy of lymphoma显示文摘考察周期的腺苷 monophosphate (营地) 的角色的目的在致病 oflymphoma 表明小径并且探索在这上指向的潜在的淋巴瘤治疗表明数据在这评论引用了的 pathway.Data 来源主要从在 Medline 和 PubMed 列出的文章被获得,从 1995 年 1 月出版了到 2009 年 6 月。搜索词是“营地”和“淋巴瘤”关于在淋巴瘤和联系房间的 apoptosis 的营地小径的角色和在在淋巴球的恶意的转变的 lymphoma.Results 的指向的治疗的 itspotential 角色的 .Study 选择文章,几条信号小径被包含。在之中他们,因为它的导致 apoptosis 角色, thecAMP 小径在几个淋巴瘤房间吸引了增加的注意。cAMPpathway 缺陷被发现影响淋巴瘤的预后。到营地小径的指向的治疗似乎是 tobe 为淋巴瘤治疗的一个新方向,瞄准恢复营地 function.Conclusions 营地信号小径在各种各样的淋巴瘤房间上有不同效果。营地类似物 andphosphodiesterase 4B (PDE4B ) 禁止者有潜在的临床的意义。然而,许多挑战仍然是 inunderstanding 如此的代理人的各种各样的角色。 | DOU Ai-xia WANG Xin | 2010 | Chinese Medical Journal2010，，1： | 10 |
| 5 | Mycoplasma pneumoniae Macrolide Resistance and MLVA Typing in Children in Beijing,China,in 2016:Is It Relevant?显示文摘Objective The aim of this study is to investigate the macrolide resistance rate and molecular type with multiple-locus variable-number tandem-repeat analysis(MLVA)of Mycoplasma pneumoniae of Beijing in 2016 in pediatric patients.Methods Real-time quantitative polymerase chain reaction(PCR)was used to identify M.pneumoniae,and MLVA was performed.The domain V of the 23 S rRNA was sequenced to detect macrolide-resistant point mutations.We also investigated the activities of antibiotics against M.pneumoniae isolates in vitro.Results The PCR detection rate of M.pneumoniae in children in Beijing was 40%,and the macrolide resistance rate was 66%.The A2063 G mutation in the 23 S rRNA V region is the dominant mutation(137/146,93.84%),whereas the A2064 G mutation is rare(9/146,6.16%).Seventy-three samples were typed successfully by MLVA typing,including 86.3%(63/73)were MLVA type 4-5-7-2,and 13.7%(10/73)were MLVA type 3-5-6-2.No other types were found.No strains were resistant to levofloxacin or tetracycline.Conclusion In 2016,a specific decrease in the macrolide resistance rate occurred in Beijing.The detection rate and macrolide resistance rate of outpatients are lower than those of inpatients.The A2063 G mutants M.pneumoniae have high levels of resistance to erythromycin and azithromycin.The primary MLVA type is 4-5-7-2,followed by 3-5-6-2.No other MLVA types were detected.No strains resistant to tetracycline or levofloxacin were found in vitro. | DOU Hai Wei TIAN Xiu Jun XIN De Li WEI Ran ZHOU Wei WANG Hong QIN Xuan Guang SHAO Jun Yan XU Bao Ping GE Li Xia SHI Da Wei | 2020 | Biomedical and Environmental Sciences2020，33，12： | 9 |
| 6 | Establishing a human pancreatic stem cell line and transplanting induced pancreatic islets to reverse experimental diabetes in rats显示文摘The major obstacle in using pancreatic islet transplantation to cure type I and some type II diabetes is the shortage of the donors. One of ways to overcome such obstacle is to isolate and clone pancreatic stem cells as 'seed cells' and induce their differentiation into functional islets as an abundant trans-plantation source. In this study, a monoclonal human pancreatic stem cell (mhPSC) line was obtained from abortive fetal pancreatic tissues. Pancreatic tissues were taken from abortive fetus by sterile procedures, and digested into single cells and cell clusters with 0.1% type IV collagenase. Cultured in modified glucose-low DMEM with 10% fetal bovine serum (FBS), these single cells and cell clusters adhered to culture dishes, and then primary epidermal-like pancreatic stem cells started to clone. After digesting with 0.25% trypsin and 0.04% EDTA, fibroblasts and other cells were gradually eliminated and epithelioid pancreatic stem cells were gradually purified during generations. Using clone-ring selection, the mhPSCs were obtained. After addition of 10 ng/mL epidermal growth factor (EGF) in cell culture medium, the mhPSCs quickly grew and formed a gravelstone-like monolayer. Continuously proliferated, a mhPSC line, which was derived from a male abortive fetus of 4 months old, has been passed through 50 generations. More than 1×109 mhPSCs were cryo-preserved in liquid nitrogen. Karyotype analysis showed that the chromosome set of the mhPSC line was normal diploid. Immunocytochemistry results demonstrated that the mhPSC line was positive for the pdx1, glucagon, nestin and CK19, and negative for the insulin, CD34, CD44 and CD45 protein expression. RT-PCR revealed further that the mhPSCs expressed transcription factors of the pdx1, glucagon, nestin and CK19. Also, in vitro induced with β-mercaptoethanol, the mhPSCs differentiated into nerve cells that expressed the NF protein. Induced with nicotinamide, the mhPSCs differentiated into functional islet-like clusters, as identified by di-thizone staining, which expressed the transcription factor of the insulin and secreted the insulin and C-peptide. Furthermore, the transplantation of mhPSCs-induced pancreatic islets into the subcapsular region of the kidney in streptozotocin-induced diabetic rats could reduce blood glucose levels and prolong the life time. | XIAO Mei AN LiLong YANG XueYi GE Xin QIAO Hai ZHAO Ting MA XiaoFei FAN JingZhuang ZHU MengYang DOU ZhongYing | 2008 | Science China(Life Sciences)2008，51，9： | 9 |
| 7 | Off-axis multi-wavelength dispersion controllingmetalens for multi-color imaging显示文摘Dispersion control is crucial in optical systems,and chromatic aberration is an important factor affecting imaging quality in imaging systems.Due to the inherent property of materials,dispersion engineering is complex and needs to trade off other aberration in traditional ways.Although metasurface offers an effective method to overcome these limits and results in well-engineered dispersion,off-axis dispersion control is still a challenging topic.In this paper,we design a single-layer metalens which is capable of focusing at three wavelengths(473 nm,532 nm,and 632 nm)with different incident angles(0°,-17°and 17°)into the same point.We also demonstrate that this metalens can provide an alternative for the bulky color synthetic prism in a 3-chips digital micromirror device(DMD)laser projection system.Through this approach,various off-axis dispersion controlling optical devices could be realized. | Kaihua Dou Xin Xie Mingbo Pu Xiong Li Xiaoliang Ma Changtao Wang Xiangang Luo | 2020 | Opto-Electronic Advances2020，3，4： | 7 |
| 8 | A Local Cluster of Omicron Variant COVID-19 Likely Caused by Internationally Mailed Document——Beijing Municipality,China,January 2022显示文摘On January 15,2022,a 26 years old female(Case A)went to a sampling site for coronavirus disease 2019(COVID-19)testing due to excessive fatigue and fever for two days.This patient preliminarily tested positive for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)using a quantitative real-time reverse transcription polymerase chain reaction(qRT-PCR)method. | Daitao Zhang Shuangsheng Wu Zhenyong Ren Ying Sun Xiangfeng Dou Zhaomin Feng Fu Li Yi Tian Shujuan Cui Baiwei Liu Bing Lyu Xiaoli Wang Feng Liu Lina Jin Chu Jiang Lina Tian Zhenjiang Xin Zhichao Liang Lei Jia Quanyi Wang Yang Pan Peng Yang | 2022 | China CDC weekly2022，4，14： | 6 |
| 9 | Multi-Objective Cooperative Salvo Attack Against Group Target显示文摘这份报纸在一个组为反对目标的多重巡航导弹的合作保留攻击的问题建议一个答案。导弹到的到达时间的同步击中他们的普通目标,最小化攻击的时间消费并且最大化期望的损坏组织目标同时被考虑。处于包括二的一个层次混合变量优化问题的这些运作的目的结果 subproblems 打字,也就是在上面的水平的多客观的导弹目标任务(MOMTA ) 问题和计划的时间最佳的协调路径(TOCPP ) 在底层的问题。以便解决挑战性的问题,计划方法的一条最近建议的协调路径被采用解决 TOCPP 问题完成不久反对每个目标的保留攻击。与为 MOMTA 发现一个更能干的解答者的目的,三个最先进的多客观的优化方法(妈妈) ,也就是 NSGA-II, MOEA/D 和 DMOEA-C,被采用。最后,一个典型例子被用来表明建议方法的优点。一个简单基于规则的方法也为比较被采用。比较结果证明 DMOEA-C 是在为解决 MOMTA 问题的三位妈妈之中的最好的选择。为 MOMTA 和为 TOCPP 计划方法的协调路径的 DMOEA-C 的联合能比基于规则的方法产生显然更好的保留攻击计划。 | ZENG Jie DOU Lihua XIN Bin | 2018 | Journal of Systems Science & Complexity2018，31，1： | 6 |
| 10 | 中国人口生育意愿变迁:1980-2011(英文)显示文摘本文基于1980—2011年间开展的227项关于中国人生育意愿的调查结果,运用横断历史元分析方法,考察了生育意愿的纵向变化趋势。研究发现:1980年以来中国人理想子女数呈减少趋势。2000年之后平均理想子女数基本稳定在1.6—1.8人之间。1980年代中国人生育水平高于生育意愿。随着经济和教育发展水平的提升,二者均呈下降趋势,但是生育水平下降快于生育意愿。1990年之后生育水平低于生育意愿,即人们实际生育子女数少于理想子女数。这为认识生育意愿和生育水平在中国的变化趋势提供了实证依据。 | 侯佳伟 Huang Silin Xin Ziqiang Sun Ling Zhang Hongchuan Dou Donghui Zhao Yuanyuan | 2015 | Social Sciences in China2015，36，1： | 5 |
| 11 | Optimizing interfacial electronic coupling with metal oxide to activate inert polyaniline for superior electrocatalytic hydrogen generation显示文摘Tuning and optimization of electronic structures and related reaction energetics are critical toward the rational design of efficient electrocatalysts.Herein,experimental and theoretical calculation demonstrate the originally inert N site within polyaniline(PANI)can be activated for hydrogen evolution by proper d-πinterfacial electronic coupling with metal oxide.As a result,the assynthesized WO3 assemblies@PANI via a facile redox-induced assembly and in situ polymerization,exhibits the electrocatalytic production of hydrogen better than other control samples including W18O49@PANI and most of the reported nobel-metal-free electrocatalysts,with low overpotential of 74 mV at 10 mA·cm−2 and small Tafel slope of 46 mV·dec−1 in 0.5M H2SO4(comparable to commercial Pt/C).The general efficacy of this methodology is also validated by extension to other metal oxides such as MoO3 with similar improvements. | Zhen-Feng Huang Jiajia Song Yonghua Du Shuo Dou Libo Sun Wei Chen Kaidi Yuan Zhengfei Dai Xin Wang | 2019 | Carbon Energy2019，1，1： | 5 |
| 12 | Accelerated methane storage in clathrate hydrates using surfactantstabilized suspension with graphite nanoparticles显示文摘In this study,enhanced kinetics of methane hydrate formation in the sodium dodecyl sulfate(SDS)solution with different concentrations of suspended graphite nanoparticles(GNPs)were investigated at 6.1-9.0 MPa and 274.15 K.The GNPs with rough surfaces and excellent thermal conductivity not only provided a considerable number of microsites for hydrate nucleation but also facilitated the fast hydrate heat transfer in the suspension system.At a relatively low pressure of 6.1 MPa,the suspension with 0.4 wt%of GNPs exhibited the minimum induction time of 22 min and maximum methane uptake of 126.1 cm3·cm-3.However,the methane storage performances of the suspensions with higher and lower concentrations of GNPs were not satisfactory.At the applied pressure,the temperature increase arising from the hydrate heat in the suspension system with the optimized concentration(0.4 wt%)of GNPs was more significant than that in the traditional SDS solution.Furthermore,compared with those of the system without GNPs,enhanced hydration rate and storage capacity were achieved in the suspensions with GNPs,and the storage capacities were increased by 3.9%-17.0%.The promotion effect of GNPs on gas hydrate formation at low pressure is much more obvious than that at high pressure. | Liang Yang Xin Wang Daoping Liu Guomin Cui Binlin Dou Juan Wang Shuqing Hao | 2020 | Chinese Journal of Chemical Engineering2020，28，4： | 4 |
| 13 | Two new compounds from Zingiber officinale显示文摘新周期的 diarylheptanoid, 1,5-epoxy-3-hydroxy-1-(3-methoxy-4,5-dihydroxyphenyl )-7-(4-hydroxyphenyl)-heptane (1 ) ,以及新单音的萜烯, 10-O- β - d-glucopyranosyl-hydroxy cineole (2 ) 从姜 officinale 的根茎被孤立。混合物的结构 1 和 2 被建立基于他们的光谱数据。另外,这些混合物的抗氧化剂活动也被测量。 | Yu Zhao Qiao Feng Tao Rong Ping Zhang Chang Xin Zhou Hui Dou Shu Yun Shi Ye Cheng Xiao Lian Li Sun Su Zeng Ke Xin Huang Xiao Dong Zhang Xiao Kun Li | 2007 | Chinese Chemical Letters2007，18，10： | 4 |
| 14 | A review of cooperative path planning of an unmanned aerial vehicle group显示文摘As a cutting-edge branch of unmanned aerial vehicle(UAV)technology,the cooperation of a group of UAVs has attracted increasing attention from both civil and military sectors,due to its remarkable merits in functionality and flexibility for accomplishing complex extensive tasks,e.g.,search and rescue,fire-fighting,reconnaissance,and surveillance.Cooperative path planning(CPP)is a key problem for a UAV group in executing tasks collectively.In this paper,an attempt is made to perform a comprehensive review of the research on CPP for UAV groups.First,a generalized optimization framework of CPP problems is proposed from the viewpoint of three key elements,i.e.,task,UAV group,and environment,as a basis for a comprehensive classification of different types of CPP problems.By following the proposed framework,a taxonomy for the classification of existing CPP problems is proposed to describe different kinds of CPPs in a unified way.Then,a review and a statistical analysis are presented based on the taxonomy,emphasizing the coordinative elements in the existing CPP research.In addition,a collection of challenging CPP problems are provided to highlight future research directions. | Hao ZHANG Bin XIN Li-hua DOU Jie CHEN Kaoru HIROTA | 2020 | Frontiers of Information Technology & Electronic Engineering2020，21，12： | 4 |
| 15 | T cell-depleting nanoparticles ameliorate bone loss by reducing activated T cells and regulating the Treg/Th17 balance显示文摘Estrogen deficiency is one of the most frequent causes of osteoporosis in postmenopausal women.Under chronic inflammatory conditions caused by estrogen deficiency,activated T cells contribute to elevated levels of proinflammatory cytokines,impaired osteogenic differentiation capabilities of bone marrow mesenchymal stem cells(BMMSCs),and disturbed regulatory T cell(Treg)/Th17 cell balance.However,therapeutic strategies that re-establish immune homeostasis in this disorder have not been well developed.Here,we produced T cell-depleting nanoparticles(TDNs)that ameliorated the osteopenia phenotype and rescued the osteogenic deficiency of BMMSCs in ovariectomized(OVX)mice.TDNs consist of monocyte chemotactic protein-1(MCP-1)-encapsulated mesoporous silica nanoparticles as the core and Fas-ligand(FasL)as the corona.We showed that the delicate design of the TDNs enables rapid release of MCP-1 to recruit activated T cells and then induces their apoptosis through the conjugated FasL both in vitro and in vivo.Apoptotic signals recognized by macrophages help skew the Treg/Th17 cell balance and create an immune tolerant state,further attenuating the osteogenic deficiency of BMMSCs and the osteopenia phenotype.Mechanistically,we found that the therapeutic effects of TDNs were partially mediated by apoptotic T cell-derived extracellular vesicles(ApoEVs),which promoted macrophage transformation towards the M2 phenotype.These findings demonstrate that TDNs may represent a promising strategy for treating osteoporosis and other immune disorders. | Xiaoshan Yang Fuxing Zhou Pingyun Yuan Geng Dou Xuemei Liu Siying Liu Xiangdong Wang Ronghua Jin Yan Dong Jun Zhou Yajie Lv Zhihong Deng Shiyu Liu Xin Chen Ying Han Yan Jin | 2021 | Bioactive Materials2021，6，10： | 4 |
| 16 | Can DKI-MRI predict recurrence and invasion of peritumoral zone of hepatocellular carcinoma after transcatheter arterial chemoembolization?显示文摘BACKGROUND Hepatocellular carcinoma(HCC)is a major cause of cancer-related mortality worldwide.Transcatheter arterial chemoembolization(TACE)has been performed as a palliative treatment for patients with HCC.However,HCC is easy to recur after TACE.Magnetic resonance imaging(MRI)has clinical potential in evaluating the TACE treatment effect for patients with liver cancer.However,traditional MRI has some limitations.AIM To explore the clinical potential of diffusion kurtosis imaging(DKI)in predicting recurrence and cellular invasion of the peritumoral liver zone of HCC after TACE.METHODSSeventy-six patients with 82 HCC nodules were recruited in this study and underwent DKI afterTACE. According to pathological examinations or the overall modified response evaluationcriteria in solid tumors (mRECIST) criterion, 48 and 34 nodules were divided into true progressionand pseudo-progression groups, respectively. The TACE-treated area, peritumoral liver zone, andfar-tumoral zone were evaluated on DKI-derived metric maps. Non-parametric U test and receiveroperating characteristic curve (ROC) analysis were used to evaluate the prediction performance ofeach DKI metric between the two groups. The independent t-test was used to compare each DKImetric between the peritumoral and far-tumoral zones of the true progression group.RESULTSDKI metrics, including mean diffusivity (MD), axial diffusivity (DA), radial diffusivity (DR), axialkurtosis (KA), and anisotropy fraction of kurtosis (Fak), showed statistically different valuesbetween the true progression and pseudo-progression groups (P < 0.05). Among these, MD, DA,and DR values were higher in pseudo-progression lesions than in true progression lesions,whereas KA and FAk values were higher in true progression lesions than in pseudo-progressionlesions. Moreover, for the true progression group, the peritumoral zone showed significantlydifferent DA, DR, KA, and FAk values from the far-tumoral zone. Furthermore, MD values of theliver parenchyma (peritumoral and far-tumoral zones) were significantly lower in the trueprogression group than in the pseudo-progression group (P < 0.05).CONCLUSIONDKI has been demonstrated with robust performance in predicting the therapeutic response ofHCC to TACE. Moreover, DKI might reveal cellular invasion of the peritumoral zone by moleculardiffusion-restricted change. | Xin Cao Hao Shi Wei-Qiang Dou Xin-Yao Zhao Ying-Xin Zheng Ya-Ping Ge Hai-Chao Cheng Dao-Ying Geng Jun-Ying Wang | 2022 | World Journal of Gastrointestinal Surgery2022，14，10： | 4 |
| 17 | Systematic review and meta-analysis of prophylactic abdominal drainage after pancreatic resection显示文摘AIM: To investigate whether prophylactic abdominal drainage is necessary after pancreatic resection. METHODS: Pub Med, Web of Science, and the Cochrane Library were systematically searched to obtain relevant articles published before January 2014. Publications were retrieved if they met the selection criteria. The outcomes of interest included: mortality, morbidity, postoperative pancreatic fistula(POPF), clinically relevant pancreatic fistula(CRPF), abdominal abscess, reoperation rate, the rate of interventional radiology drainage, and the length of hospital stay. Subgroup analyses were also performed for pancreaticoduodenectomy(PD) and for distal pancreatectomy. Begg's funnel plot and the Egger regression test were employed to assess potential publication bias.RESULTS: Nine eligible studies involving a total of 2794 patients were identified and included in this meta-analysis. Of the included patients, 1373 received prophylactic abdominal drainage. A fixedeffects model meta-analysis showed that placement of prophylactic drainage did not have beneficial effects on clinical outcomes, including morbidity, POPF, CRPF, reoperation, interventional radiology drainage, and length of hospital stay(Ps > 0.05). In addition, prophylactic drainage did not significantly increase the risk of abdominal abscess. Overall analysis showed that omitting prophylactic abdominal drainage resulted in higher mortality after pancreatectomy(OR = 1.56; 95%CI: 0.93-2.92). Subgroup analysis of PD showed similar results to those in the overall analysis. Elimination of prophylactic abdominal drainage after PD led to a significant increase in mortality(OR = 2.39; 95%CI: 1.22-4.69; P = 0.01).CONCLUSION: Prophylactic abdominal drainage after pancreatic resection is still necessary, though more evidence from randomized controlled trials assessing prophylactic drainage after PD and distal pancreatectomy are needed. | Chang-Wei Dou Zhi-Kui Liu Yu-Li Jia Xin Zheng Kang-Sheng Tu Ying-Min Yao Qing-Guang Liu | 2015 | World Journal of Gastroenterology2015，21，18： | 4 |
| 18 | KB4Rec:A Data Set for Linking Knowledge Bases with Recommender Systems显示文摘To develop a knowledge-aware recommender system,a key issue is how to obtain rich and structured knowledge base(KB)information for recommender system(RS)items.Existing data sets or methods either use side information from original RSs(containing very few kinds of useful information)or utilize a private KB.In this paper,we present KB4Rec v1.0,a data set linking KB information for RSs.It has linked three widely used RS data sets with two popular KBs,namely Freebase and YAGO.Based on our linked data set,we first preform qualitative analysis experiments,and then we discuss the effect of two important factors(i.e.,popularity and recency)on whether a RS item can be linked to a KB entity.Finally,we compare several knowledge-aware recommendation algorithms on our linked data set. | Wayne Xin Zhao Gaole He Kunlin Yang Hongjian Dou Jin Huang Siqi Ouyang Ji-Rong Wen | 2019 | Data Intelligence2019，1，2： | 3 |
| 19 | Epidemiological Investigation of an Inhalational Anthrax Patient Traveling for Medical Treatment in Beijing Municipality,China,August 2021显示文摘Summary What is already known about this topic?Inhalational anthrax,also known as pulmonary anthrax,is an infectious disease caused by Bacillus anthracis.The patients are usually infected by inhaling aerosolized B.anthracis spores from dead animals or animal products.Compared to cutaneous anthrax,inhalational anthrax is rare and deadly and few cases in China were reported.What is added by this report?This report covers all information of clinical features,laboratory testing,and epidemiological characteristics as well as exposure history of a recent primary inhalational anthrax patient who was seeking medical treatment in Beijing Municipality in August 2021.New laboratory techniques,including second-generation sequencing,polymerase chain reaction,and rapid test for serum antibody,played an important role in the process.What are the implications for public health practice?The information provided in this report,including the correct sample type,epidemiological investigation details,and application of the new diagnostic criteria of anthrax,could assist public health professionals in dealing with anthrax epidemics. | Changying Lin Xiangfeng Dou Daitao Zhang Yinqi Sun Huiqiang Han Chunzhi Chen Xiaojun Zhang Shuang Li Yanwei Chen Hongbin Zhang Bin Wang Zhichao Liang Xin Zhang Feng Wei Jiangli Wang Feng Liu Quanyi Wang Jian Shi Peng Yang | 2022 | China CDC weekly2022，4，1： | 3 |
| 20 | Cyclic adenosine monophosphate involvement in low-dose cyclophosphamide-reversed immune evasion in a mouse lymphoma model显示文摘淋巴瘤房间动员许多机制躲避免疫系统。有实质的证据那 CD4 + 规章的 T 房间(Tregs ) 玩的 CD25 + 在有免疫力的避免的控制的一个关键角色。Tregs 能把周期的腺苷 monophosphate (营地) 转移到受动器 T 房间,建议在 Treg 的有免疫力避免的角色和细胞内部的营地小径之间的一个协会。在这研究,当好攻击的肿瘤当模特儿由低剂量的 cyclophosphamide 调查 Tregs 的弄空的机制,我们使用了 A20 B 房间淋巴瘤老鼠(CY, 20mg/kg ) 。忍受肿瘤的老鼠有更长的幸存时间和与 CY 跟随处理的更慢的肿瘤生长率,但是它的效果是暂时的。与由低剂量的 CY 处理的 Tregs 的弄空一起,在 T 受动器房间的 interleukin-2 (IL-2 ) 的表示增加了,并且在有免疫力的房间的细胞内部的营地集中减少了。我们的学习表明低剂量的 CY 的能力在一个老鼠模型颠倒调停 Tregs 的有免疫力的避免。在细胞内部的营地集中的变化与受动器 T 房间的 upregulation 和 Tregs 的 downregulation 相关,显示在 B 房间淋巴瘤的有免疫力的治疗的营地类似物和低剂量的 CY 的靠近的协会。 | Ai-Xia Dou Li-Li Feng Xiao-Qian Liu Xin Wang | 2012 | Cellular & Molecular Immunology2012，9，6： | 3 |
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