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| 1 | A LysM Receptor Heteromer Mediates Perception of Arbuscular Mycorrhizal Symbiotic Signal in Rice显示文摘Symbiotic microorganisms improve nutrient uptake by plants.To initiate mutualistic symbiosis with arbus-cular mycorrhizal(AM)fungi,plants perceive Myc factors,including lipochitooligosaccharides(LCOs)and short-chain chitooligosaccharides(CO4/CO5),secreted by AM fungi.However,the molecular mechanism of Myc factor perception remains elusive.In this study,we identified a heteromer of LysM receptor-like kinases consisting of OsMYR1/OsLYK2 and OsCERK1 that mediates the perception of AM fungi in rice.CO4 directly binds to OsMYR1,promoting the dimerization and phosphorylation of this receptor complex.Compared with control plants,Osmyr1 and Oscerk1 mutant rice plants are less sensitive to Myc factors and show decreased AM colonization.We engineered transgenic rice by expressing chimeric receptors that respectively replaced the ectodomains of OsMYR1 and OsCERK1 with those from the homologous Nod factor receptors MtNFP and MtL YK3 of Medicago truncatula.Transgenic plants displayed increased cal-cium oscillations in response to Nod factors compared with control rice.Our study provides significant mechanistic insights into AM symbiotic signal perception in rice.Expression of chimeric Nod/Myc recep-tors achieves a potentially important step toward generating cereals that host nitrogen-fixing bacteria. | Jiangman He Chi Zhang Huiling Dai Huan Liu Xiaowei Zhang Jun Yang Xi Chen Yayun Zhu Dapeng Wang Xiaofeng Qi Weichao Li Zhihui Wang Guoyong An Nan YU Zuhua He Yong-Fei Wang Youli Xiao Peng Zhang Ertao Wang | 2019 | Molecular Plant2019，12，12： | 9 |
| 2 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 3 | The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages显示文摘Lipid metabolic reprogramming plays an essential role in regulating the progression of colorectal cancer(CRC).However,the effect of lysophosphatidic acid(LPA)metabolism on CRC development is incompletely characterized.Here,we compared the mRNA levels of human CRC tissues to those of paracarcinoma tissues and focused on the notably enriched LPA metabolic pathways.We identified and verified that 1-acylglycerol-3-phosphate O-acyltransferase 4(Agpat4)was aberrantly expressed in CRC tissues and predicted poor survival in CRC patients.Manipulating Agpat4 expression in CRC cells did not affect the growth or migration of CRC cells in vitro,whereas Agpat4 silencing suppressed CRC cell growth in subcutaneous and peritoneal xenograft models.Mechanistically,Agpat4 silencing-induced LPA release from CRC cells and polarized macrophages to an M1-like phenotype through LPA receptors 1 and 3.This M1 activation,characterized by elevated p38/p65 signaling and increased proinflammatory cytokines,promoted the infiltration and activation of CD4+and CD8+T cells in the tumor microenvironment.Modulation of the Agpat4/LPA/p38/p65 axis regulated macrophage polarization,T-cell activity and CRC progression.Notably,combined therapy with LPA and regular chemotherapy drugs synergistically suppressed CRC development.Taken together,our results showed that the Agpat4/LPA axis in CRC cells regulated p38/p65 signaling-dependent macrophage polarization,T-cell activation,and CRC progression.The Agpat4/LPA/p38/p65 axis might represent a potential target for therapy in the clinic. | Dapeng Zhang Rongchen Shi Wei Xiang Xia Kang Bo Tang Chuan Li Linfeng Gao Xuan Zhang Lili Zhang Rongyang Dai Hongming Miao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 3 |
| 4 | HYSYS Automation and Its Application on Evaluation of Plate Heat Exchanger显示文摘当为 multicomponent 混合物模仿或设计板热 exchangers 时,大多数设计者经常与怎么选择或估计物理性质参数和希望有能被采用的一个可靠数据库上的问题被困惑。商业代码 HYSYS 供应为 them.This 工作的超过 1500 种纯物质和超过 16 000 个二进制系数上的物理性质包裹简短基于在内部板热 exchanger 模拟代码和 HYSYS 包裹之间的微软部件对象模型(COM ) 介绍了一个有效通讯接口。一个定做的 HYSYS-COM 接口的应用程序显示出高效率,例如为评估每条过程溪流的性质需要的时间的重要减小。这个自动化方法能方便地被扩大为象热转移,列,和另外的设备那样的任何特定的操作设备推进优化学习。 | Dai Yuqiang Liu Wenwei Wang Shaomin Hu Dapeng | 2008 | China Petroleum Processing & Petrochemical Technology2008，10，3： | 3 |
| 5 | Multifunctional geometric phase optical element for high-efficiency full Stokes imaging polarimetry显示文摘Polarization imaging finds applications in many areas, such as photoelasticity, ellipsometry, and biomedical imaging. A compact, snapshot, and high-efficiency imaging polarimeter is highly desirable for many applications.Here, based on a single multifunctional geometric phase optical element(GPOE), a new method is proposed for high-efficiency snapshot imaging polarimetry. With tailored spatially varying orientation of each anisotropic unit cell, the GPOE works highly efficiently as both a spin sorter and a half-wave plate, enabling snapshot retrieving of a full Stokes vector of incident light. The designed GPOE is implemented in the form of liquid crystal fabricated with a photo-alignment technology, and its application in imaging polarimetry is experimentally demonstrated by retrieving full Stokes parameters of a cylinder vector beam. This method can also work in the form of plasmonic or dielectric metasurfaces, enabling ultra-compact polarization detection systems by monolithic integration with other devices such as metalenses. | YANMENG DAI YUQUAN ZHANG YOUPENG XIE DAPENG WANG XIANYOU WANG ITING LEI CHANGJUN MIN XIAOCONG YUAN | 2019 | Photonics Research2019，7，9： | 3 |
| 6 | Cable-truss supporting system for gob-side entry driving in deep mine and its application显示文摘In order to solve the large deformation controlling problem for surrounding rock of gob-side entry driving under common cable anchor support in deep mine, site survey, physical modeling experiment, numerical simulation and field measurement were synthetically used to analyze the deformation and failure characteristics of surrounding rock. Besides, applicability analysis, prestress field distribution characteristics of surrounding rock and the control effect on large deformation of surrounding rock were also further studied for the gob-side entry driving in deep mine using the cable-truss supporting system. The results show that, first, compared with no support and traditional bolt anchor support, roof cable-truss system can effectively restrain the initiation and propagation of tensile cracks in the roof surrounding rock and arc shear cracks in the two sides, moreover, the broken development of surrounding rock, roof separation and extrusion deformation between the two sides of the roadway are all controlled; second, a prestressed belt of trapezoidal shape is generated in the surrounding rock by the cable-truss supporting system, and the prestress field range is wide. Especially, the prestress concentration belt in the shallow surrounding rock can greatly improve the anchoring strength and deformation resisting capability of the rock stratum;third, an optimized support system of ‘‘roof and side anchor net beam, roof cable-truss supporting system and anchor cable of the narrow coal pillar' was put forward, and the support optimization design and field industrial test were conducted for the gob-side entry driving of the working face 5302 in Tangkou Mine, from which a good supporting effect was obtained. | Yin Qian Jing Hongwen Dai Dapeng Zhu Tantan Zhao Honghui Meng Bo | 2016 | International Journal of Mining Science and Technology2016，26，5： | 3 |
| 7 | Study on gas and wave in a receiving tube显示文摘气体和波浪是在一个收到的试管的运动在现在的纸数字地并且试验性地被调查。结果显示出那,当气体在稳定的繁殖以后严厉地被注入收到的试管,然后落下,接触脸的速度很快升起。然而,在试管的波浪的速度是几乎线性的,波浪能在收到的试管的靠近的结束被反映。与入口压力增加,波浪的速度和接触脸的稳定的速度也增加。当波浪打扫气体,有明显的热效果。反映的波浪能在开的结束加热令人疲乏不堪的气体。作为一个吸收器,在试管罐头的扩展和一位精神病医生几乎完全吸收反映的波浪。 | Dapeng Hu Shengtao Chen Jun Yang Zuzhi Chen Yuqiang Dai Che Zhu Runjie Liu | 2008 | Journal of Thermal Science2008，17，2： | 2 |
| 8 | 电磁监测试验卫星及其初步成果显示文摘As the first satellite of the China national geophysical field observation series of stllite missions,the China Seismo--Electromagnetic Satellite(CSES)was designed upon an optimized CAST2000 platform for a sun synchronous orbit.Onboard CSES,there are total eight types of scientific payloads including the Search-coil Magnetometer,Electric Field Detector,High Precision Magnetometer,GNSS Occupation Receiver,Plasma Analyzer,Langmuir Probe,Energetic Particle Detector Package,and a Three-band Transmitter to individually acquire the global eletromagnetic field,elec-tromagnetic waves,ionospheric plasma parameters as well as energetic particles.Up to now,CSES has been operating normally in orbit for 2 years.By using the various sensor data acquired by CSES,we have achieved scientfic research in the areas of the global geomagnetic field modeling,space weather,earthquake event analysis,the Lithosphere-Atmo-sphere-lonosphere coupling mechanism and so on.. | SHEN Xuhui ZEREN Zhima YUAN Shigeng DAI Jianping HUANG Jianping ZHU Xinghong YANG Yanyan YAN Rui ZHAO Shufan LIU Dapeng ZHANG Zhenxia WANG Qiao CHU Wei LU Hengxin XU Song GUO Feng TAN Qiao LI Wenjing ZHOU Na | 2020 | Aerospace China2020，21，1： | 2 |
| 9 | Study on Wall Temperature Distribution of Oscillating Tube显示文摘The wall temperature distribution and heat transfer process of the oscillating tube have been investigated in thispaper using both numerical simulation and experimental method. The wall temperature of oscillating tube increasesrapidly in the inlet and then decreases slowly, moreover, the rally phenomenon of wall temperature nearthe closed end is observed. With the increase of jet flow frequency, the highest wall temperature increases and thelocation of that moves towards the inlet. The velocity of pressure wave in the oscillating tube almost remainsconstant even its intensity changes. The quantity of heat transfer between the gas and inner wall of the oscillatingtube determines the wall temperature of every location, and the pressure wave disturbance can cause the heattransfer quantity change. Each pressure wave has its own disturbance range. The wall temperature distribution canbe explained by the change of pressure wave intensity and its disturbance time. Besides, the step and rally of walltemperature are discussed, which shows that the conditions of heat transfer can be improved due to intersection orreflection of pressure waves. | Dapeng HU Peiqi LIU Wenjing ZHAO Che ZHU Yudong WANG Yuqiang DAI Jiupeng ZOU | 2009 | Journal of Thermal Science2009，18，3： | 2 |
| 10 | Feasibility of Intermediate Fluid Vaporizer with Spiral Wound Tubes显示文摘A novel intermediate fluid vaporization (IFV) technology for LNG re-gasification process with spiral-wound heat exchanging tubes is proposed. The new IFV project combines the advantage of running the shell and tube heat exchangers at high pressure with the advantage of compact space of heat exchangers. Thermal analysis on the two processes of forced convection and vaporization type heat transfer in the spiral wound tubes and vapor condensation /re-boiling type of heat transfer via intermediate fluid in shell side shows the feasibility of this promising technology. | Liu Fengxia Dai Yuqiang Wei Wei Zou Jiupeng Zhu Che Dong Chao Hu Dapeng | 2013 | China Petroleum Processing & Petrochemical Technology2013，15，1： | 2 |
| 11 | Catalyst-Free In Situ Carbon Nanotube Growth in Confined Space via High Temperature Gradient显示文摘Carbonaceous materials,such as graphite,carbon nanotubes(CNTs),and graphene,are in high demand for a broad range of applications,including batteries,capacitors,and composite materials.Studies on the transformation between diferent types of carbon,especially from abundant and low-cost carbon to high-end carbon allotropes,have received surging interest.Here,we report that,without a catalyst or an external carbon source,biomass-derived amorphous carbon and defective reduced graphene oxide(RGO)can be quickly transformed into CNTs in highly confned spaces by high temperature Joule heating.Combined with experimental measurements and molecular dynamics simulations,we propose that Joule heating induces a high local temperature at defect sites due to the corresponding high local resistance.Te resultant temperature gradient in amorphous carbon or RGO drives the migration of carbon atoms and promotes the growth of CNTs without using a catalyst or external carbon source.Our fndings on the growth of CNTs in confned spaces by fast high temperature Joule heating shed light on the controlled transition between diferent carbon allotropes,which can be extended to the growth of other high aspect ratio nanomaterials. | Chaoji Chen Yanan Chen Shuze Zhu Jiaqi Dai Glenn Pastel Yonggang Yao Dapeng Liu Yanbin Wang Jiayu Wan Teng Li Wei Luo Liangbing Hu | 2018 | Research2018，，1： | 2 |
| 12 | Improving the Rapidity of Nonlinear Tracking Differentiator via Feedforward显示文摘 | Tian Dapeng Shen Honghai Dai Ming | 2014 | IEEE Trans on Ind Electron2014，61，7： | 1 |
| 13 | Nitrogen‐Doped Holey Graphitic Carbon from 2D Covalent Organic Polymers for Oxygen Reduction显示文摘 | Zhonghua Xiang Dapeng Cao Ling Huang Jianglan Shui Min Wang Liming Dai | 2014 | Adv. Mater2014，，20： | 1 |
| 14 | Study on wave rotor refrigerators显示文摘As a novel generation of a rotational gas wave machine,the wave rotor refrigerator(WRR)is an unsteadyflow device used for refrigeration,in whose passages pressured streams directly contact and exchange energy due to the movement of pressure waves.In this paper,the working mechanism and refrigeration principle are inves-tigated based on the one-dimensional unsteadyflow theory.A basic limitation on main structural parameters and operating parameters is deduced and the wave diagram of WRR to guide designing is sketched.The main influential factors are studied through an experiment.In the DUT Gas Wave Refrigeration Studying and Development Center(GWRSDC)lab,the isentropic efficiency can now reach about 65%.The results show that the WRR is a feasible and promising technology in pressured gas refrigeration cases. | Yuqiang DAI Dapeng HU Meixia DING | 2009 | Frontiers of Chemical Science and Engineering2009，3，1： | 0 |
| 15 | Approach to 2′-(Dialkylamino)-1-alkyl-4′H-spiro[indoline-3,5′-oxazole]-2,4′-diones and 1,3-Oxazin-4-ones via Cyclization of Vilsmeier Salts withα-Hydroxy andβ-Carbonyl Amides显示文摘A straiglitforward and efficient synthetic method of 2′-(dialkylammo)-l-alkyl-4′H-spiro[indoline-3,5′-oxazole]-2,4′-diones and 2-(dialkylamino)-5,6-dihydro-4H-naphtho[2,1-e][1,3]oxazin-4-one-derivatives have been developed from a-hydroxy andβ-carbonyl amides and various Vilsmeier salts.A wide range of heterocyclic compounds were obtained in excellent yields(up to 97%),which will provide promising candidates lor chemical biology and drug discovery. | DAI Jianan LIU Bengen WEI Zhonglin CAO Jungang LIANG Dapeng DUAN Haifeng LIN Yingjie | 2019 | Chemical Research in Chinese Universities2019，35，2： | 0 |
| 16 | Numerical Simulations on Geometrical Properties of Wall-attaching Transonic Jet显示文摘Effects of operating conditions and device's geometrical sizes on geometrical properties of wall-attaching transonic jet between two parallel plat plates are numerically simulated. Conclusions are as follows: 1) Upriver part of the wall-attaching jet's center streamline is in good accordance with parabola; 2) When both gas inlet pressure and outlet pressure as well as their ratio are not too high ( the outlet pressure is less than 10 MPa and the pressure ratio is less than 3), the center streamlines of the wall-attaching jet with the same pressure ratio coincide with each other very well, and the deflection degree of the center streamline decreases with rise of the pressure ratio; 3) The deflection degree of the jet's center streamline decreases with either broadening of nozzle's throat or rise of wall offset; 4) With rise of the pressure ratio, attachment distance of the jet increases, but the increase rate descends; 5) The attachment distance ascends with rise of either the nozzle's throat or the wall offset. | Hu Dapeng Chen Zuzhi Dai Yuqiang Chen Shengtao | 2008 | Engineering Sciences2008，6，1： | 0 |
| 17 | 中国北京地区部分医院患者疼痛现状调查(英文)显示文摘Objective:This study aimed to survey the characteristics and treatments of cancer pain in Beijing hospitals,China.Methods:At 20:00 on December 22,2009,there conducted a questionnaire survey in 2238 patients with malignant tumors of 26 hospitals in Beijing,and the survey results were statistically analyzed.Results:The 531 cases in 2238 patients had pained and 121 cases (22.79%) had outbreak pain with one week.At 20:00 on December 22,2009,199 cases (38%) in the above-mentioned 531 pain patients suffered the moderate to severe pain (pain scores ≥ 4).The number of pain (pain scores ≥ 4) patients in the consecutive three days from December 20 to December 22 were 150.Conclusion:In the 531 cancer pain patients of the surveyed hospitals,38% of the patients were not satisfied with the pain control.Doctors believed that the main reason for pain not controlled was the non-standard treatment,but patients considered to be afraid of addiction. | Shikai Wu Fang Li Pingping Li Jian Luo Xiaoming Wu Heling Shi Xiaohong Ning Yufei Yang Huangying Tan Ping Yang Guangqing Zhu Jianhua Zhu Guoqing Liao Huoming Chen Dapeng Lv Ye Fang Hong Dai Xiaoming Xi Xiuhua Li Yuan Qin Li Feng Su Wang Xiaoyan Chen Hongyong Wang Hongyan Li Duanqi Liu | 2012 | The Chinese-German Journal of Clinical Oncology2012，11，6： | 0 |
| 18 | Construction and characterization of a humanized anti-human CD3 monoclonal antibody 12F6 with effective immunoregulation functions显示文摘 | Bohua Li Hao Wang Jianxin Dai Junjie Ji Weizhu Qian Dapeng Zhang Sheng Hou Yajun Guo | 2006 | 中国生物学文摘2006，20，1： | 0 |
| 19 | A nanoforest-based humidity sensor for respiration monitoring显示文摘Traditional humidity sensors for respiration monitoring applications have faced technical challenges,including low sensitivity,long recovery times,high parasitic capacitance and uncalibrated temperature drift.To overcome these problems,we present a triple-layer humidity sensor that comprises a nanoforest-based sensing capacitor,a thermistor,a microheater and a reference capacitor.When compared with traditional polyimide-based humidity sensors,this novel device has a sensitivity that is improved significantly by 8 times within a relative humidity range of 40-90%.Additionally,the integration of the microheater into the sensor can help to reduce its recovery time to 5 s.The use of the reference capacitor helps to eliminate parasitic capacitance,and the thermistor helps the sensor obtain a higher accuracy.These unique design aspects cause the sensor to have an excellent humidity sensing performance in respiration monitoring applications.Furthermore,through the adoption of machine learning algorithms,the sensor can distinguish different respiration states with an accuracy of 94%.Therefore,this humidity sensor design is expected to be used widely in both consumer electronics and intelligent medical instrument applications. | Guidong Chen Ruofei Guan Meng Shi Xin Dai Hongbo Li Na Zhou Dapeng Chen Haiyang Mao | 2022 | Microsystems & Nanoengineering2022，8，2： | 0 |
| 20 | Artificial synapses based on organic electrochemical transistors with self-healing dielectric layers显示文摘Organic electrochemical transistors(OECTs)have emerged as one type of promising building block for neuromorphic systems owing to their capability of mimicking the morphology and functions of biological neurons and synapses.Currently,numerous kinds of OECTs have been developed,while self-healing performance has been neglected in most reported OECTs.In this work,the OECTs using self-healing polymer electrolytes as dielectric layers are proposed.Several important synaptic behaviors are simulated in the OECTs by doping the channel layers with ions from the electrolytes.Benefitting from the dynamic hydrogen bonds in the self-healing polymer electrolytes,the OECTs can successfully maintain their electrical performance and the ability of emulating synaptic behaviors after self-healing compared with the initial state.More significantly,the sublinear spatial summation function is demonstrated in the OECTs and their potential in flexible electronics is also validated.These results suggest that our devices are expected to be a vital component in the development of future wearable and bioimplantable neuromorphic systems. | Yushan Gao Junyao Zhang Dapeng Liu Tongrui Sun Jun Wang Li Li Shilei Dai Jianhua Zhang Zhenglong Yang Jia Huang | 2024 | Chinese Chemical Letters2024，35，3： | 0 |
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