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| 1 | Phytoplankton community structure and environmental parameters in aquaculture areas of Daya Bay,South China Sea显示文摘Environmental characteristics and phytoplankton community structure were investigated in two aquaculture areas in Dapeng Cove of Daya Bay,South China Sea,between April 2005 and June 2006.Phytoplankton abundance ranged between 5.0 and 8877.5 cells/mL,with an average of 751.8 cells/mL.The seasonal cycle of phytoplankton were demonstrated by frequent oscillations,with recurrent high abundances from late spring to autumn and a peak stage in late winter.Diatoms were the predominant phytoplankton group,accounting for 93.21%of the total abundance.The next most abundant group was the dinoflagellates,which made up only 1.24%of total abundance. High concentrations of Alexandrium tamarense(Lebour) Balech with a maximum of 603.0 cells/mL were firstly recorded in this area known for high rates of paralytic shellfish poisoning(PSP) contamination.Temperatures and salinities were within the suitable values for the growth of phytoplankton,and were important in phytoplankton seasonal fluctuations.The operation of the Daya Bay Nuclear Power Station(DNPS) exerts influences on the phytoplankton community and resulted in the high abundances of toxic dinoflagellate species during the winter months.Dissolved inorganic nitrogen(DIN) and dissolved silicate(DSi) were suffcient,and rarely limited for the growth of phytoplankton.Dissolved inorganic phosphorus(DIP) was the most necessary element for phytoplankton growth. The enriched environments accelerated the growth of small diatoms,and made for the shift in predominant species from large diatom Rhizosolenia spp.to chain-forming diatoms such as Skeletonema costatum,Pseudo-nitzschia spp.and Thalassiosira subtilis. | WANG Zhaohui ZHAO Jiangang ZHANG Yujuan CAO Yu | 2009 | Journal of Environmental Sciences2009，21，9： | 44 |
| 2 | A life support-based comprehensive treatment regimen dramatically lowers the in-hospital mortality of patients with fulminant myocarditis: a multiple center study显示文摘Fulminant myocarditis(FM) has unacceptable high mortality. This study aimed to evaluate the therapeutic efficacy of a life support-based comprehensive treatment regimen(LSBCTR), a completely novel treatment regimen, for FM. A total of 169 FM patients recruited from January 2008 to December 2018 were divided into two groups: patients receiving LSBCTR(81 cases),which includes(i) mechanical life support(positive pressure respiration, intra-aortic balloon pump with or without extracorporeal membrane oxygenation),(ii) immunomodulation therapy using sufficient doses of glucocorticoids and immunoglobulins, and(iii) application of neuraminidase inhibitors, and those receiving conventional treatment(88 cases). The endpoints were in-hospital death and heart-transplantation. Of all the population, 44 patients(26.0%) died in hospitals. Inhospital mortality was 3.7%(3/81) for LSBCTR group and 46.6%(41/88) for traditional treatment(P<0.001). Early application of LSBCTR, mechanical life support, neuraminidase inhibitors, and immunomodulation therapy significantly contributed to reduction in in-hospital mortality. This study describes a novel treatment regimen for FM patients that dramatically reduces inhospital mortality. Its generalization and clinical application will efficiently save lives although further optimization is needed.This study offers an insight that virus infection induced inflammatory waterfall results in cardiac injury and cardiogenic shock and is the therapeutic target. | Sheng Li Shengyong Xu Chenze Li Xiao Ran Guanglin Cui Mengying He Kun Miao Chunxia Zhao Jiangtao Yan Rutai Hui Ning Zhou Yan Wang Jiangang Jiang Jing Zhang Daowen Wang | 2019 | Science China(Life Sciences)2019，62，3： | 43 |
| 3 | Constraining the timing of the India-Asia continental collision by the sedimentary record显示文摘Placing precise constraints on the timing of the India-Asia continental collision is essential to understand the successive geological and geomorphological evolution of the orogenic belt as well as the uplift mechanism of the Tibetan Plateau and their effects on climate,environment and life.Based on the extensive study of the sedimentary record on both sides of the Yarlung-Zangbo suture zone in Tibet,we review here the present state of knowledge on the timing of collision onset,discuss its possible diachroneity along strike,and reconstruct the early structural and topographic evolution of the Himalayan collided range.We define continent-continent collision as the moment when the oceanic crust is completely consumed at one point where the two continental margins come into contact.We use two methods to constrain the timing of collision onset:(1) dating the provenance change from Indian to Asian recorded by deep-water turbidites near the suture zone,and(2) dating the age of unconformities on both sides of the suture zone.The first method allowed us to constrain precisely collision onset as middle Palaeocene(59±l Ma).Marine sedimentation persisted in the collisional zone for another 20-25 Ma locally in southern Tibet,and molassic-type deposition in the Indian foreland basin did not begin until another 10-15 Ma later.Available sedimentary evidence failed to firmly document any significant diachroneity of collision onset from the central Himalaya to the western Himalaya and Pakistan so far.Based on the Cenozoic stratigraphic record of the Tibetan Himalaya,four distinct stages can be identified in the early evolution of the Himalayan orogen:(1) middle Palaeocene-early Eocene earliest Eohimalayan stage(from 59 to 52 Ma):collision onset and filling of the deep-water trough along the suture zone while carbonate platform sedimentation persisted on the inner Indian margin;(2) early-middle Eocene early Eohimalayan stage(from 52 to 41 or 35 Ma):filling of intervening seaways and cessation of marine sedimentation;(3) late Eocene-Oligocene late Eohimalayan stage(from 41 to 25 Ma):huge gap in the sedimentary record both in the collision zone and in the Indian foreland;and(4) late Oligocene-early Miocene early Neohimalayan stage(from 26 to 17 Ma):rapid Himalayan growth and onset of molasse-type sedimentation in the Indian foreland basin. | HU XiuMian WANG JianGang AN Wei Eduardo GARZANTI LI Juan | 2017 | Science China Earth Sciences2017，60，4： | 32 |
| 4 | Chinese expert consensus statement on the diagnosis and treatment of fulminant myocarditis显示文摘Fulminant myocarditis is primarily caused by infection with any number of a variety of viruses. It arises quickly, progresses rapidly, and may lead to severe heart failure or circulatory failure presenting as rapid-onset hypotension and cardiogenic shock,with mortality rates as high as 50%–70%. Most importantly, there are no treatment options, guidelines or an expert consensus statement. Here, we provide the first expert consensus, the Chinese Society of Cardiology Expert Consensus Statement on the Diagnosis and Treatment of Fulminant Myocarditis, based on data from our recent clinical trial(NCT03268642). In this statement, we describe the clinical features and diagnostic criteria of fulminant myocarditis, and importantly, for the first time,we describe a new treatment regimen termed life support-based comprehensive treatment regimen. The core content of this treatment regimen includes(i) mechanical life support(applications of mechanical respirators and circulatory support systems,including intraaortic balloon pump and extracorporeal membrane oxygenation),(ii) immunological modulation by using sufficient doses of glucocorticoid, immunoglobulin and(iii) antiviral reagents using neuraminidase inhibitor. The proper application of this treatment regimen may and has helped to save the lives of many patients with fulminant myocarditis. | Daowen Wang Sheng Li Jiangang Jiang Jiangtao Yan Chunxia Zhao Yan Wang Yexin Ma Hesong Zeng Xiaomei Guo Hong Wang Jiarong Tang Houjuan Zuo Li Lin Guanglin Cui Section of Precision Medicine Group of Chinese Society of Cardiology,Editorial Board of Chinese Journal of Cardiology &Working Group of Adult Fulminant Myocarditis | 2019 | Science China(Life Sciences)2019，62，2： | 18 |
| 5 | ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13显示文摘这研究的目的是在房间增长和肺腺癌的 autophagy 调查 apelin 的角色。在肺腺癌的 APJ 的在表示上被 immunohistochemistry 检测,当在肺癌症病人的血浆 apelin 水平被连接酶的 immunosorbent 试金测量时。我们的调查结果表明 apelin-13 显著地增加了 ERK1/2 的 phosphorylation, cyclin D1 的表示,联系微导管的蛋白质 1 轻链 3A/B (LC3A/B ) ,和 beclin1,并且证实 apelin-13 支持了 A549 房间增长并且经由 ERK1/2 发信号导致了 A549 房间 autophagy。而且,人的肺腺癌房间线 A549 的表面和光滑、光滑的 apelin-13 原因房间表面上有毛孔是在原子力量下面观察了显微镜学。这些结果建议 ERK1/2 发信号小径调停 apelin-13-induced 肺腺癌房间增长和 autophagy。在我们的试验性的条件下面,与 3-methyladenine 联系的 autophagy 不涉及房间增长。 | Li Yang Tao Su Deguan Lv FengXie Wei Liu Jiangang Cao Irshad Ali Sheikh Xuping Qin Lanfang Li Linxi Chen | 2014 | Acta Biochimica et Biophysica Sinica2014，46，2： | 15 |
| 6 | Comparisons in subcellular and biochemical behaviors of cadmium between Iow-Cd and high-Cd accumulation cultivars of pakchoi (Brassica chinensis L.)显示文摘 | Meng XUE Yihui ZHOU Zhongyi YANG Biyun LIN Jiangang YUAN Shanshan WU | 2014 | Frontiers of Environmental Science & Engineering2014，8，2： | 14 |
| 7 | Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders: executive summary and 2019 update of clinical management of cerebral venous sinus thrombosis显示文摘Aim Cerebral venous sinus thrombosis(CVST)is a less common cerebrovascular disease that predominantly affects young patients.The incidence of CVST is 2-5/10000000/year,accounting for 0.5%-1%of all stroke.To reduce mortality and morbidity associated with CVST,Chinese Stroke Association commissioned the authors to write the current guideline on the management of CVST.Methods PubMed(MEDLINE),CNKI and Wanfang database were searched for studies related to CVST from 1 January 1990 to 31 July 2019.Data were synthesised by evidence tables.Each recommendation was fully discussed by the writing group members and reviewed by Chinese Stroke Association Stroke Fellow Committees.Levels of evidence grading algorithm of Chinese Stroke Association was used to grade each recommendation.results This guideline mainly focuses on the diagnostic evaluation,therapeutic strategies and secondary prevention of CVST.CT/CTV and MRI/MRV are recommended in the initial imaging evaluation of patients with suspected CVST.Anticoagulation therapy with low-molecular weight heparin should be initiated in patients with CVST immediately.After the acute stage,warfarin is recommended for 3-6 months to prevent the recurrence of CVST and other venous thromboembolic events.Conclusions The guideline summarises the current evidence regarding the management of CVST,and provides references for diagnosis,treatment and secondary prevention of CVST in China. | Yuhua Fan Jian Yu Hongbing Chen Jian Zhang Jiangang Duan Dapeng Mo Wenhao Zhu Bo Wang Fubing Ouyang Yicong Chen Linfang Lan Jinsheng Zeng Chinese Stroke Association Stroke Council CVST Guideline Writing Committee | 2020 | Stroke & Vascular Neurology2020，5，2： | 14 |
| 8 | Impact of mechanical circulatory support and immunomodulation therapy on outcome of patients with fulminant myocarditis: Chinese registry of fulminant myocarditis显示文摘Dear Editor,Patients presenting with acute myocarditis and sudden hemodynamic instability (termed fulminant myocarditis [FM]) still have a high mortality and need for heart transplantation, up to 28% at 60 days.1,2,3 Recent scientific statements and expert opinion consensus suggests early use of temporary mechanical circulatory supports (t-MCS).3,4 Specifically, Chinese scientific statement proposed an extensive use of t-MCS combined with immunoregulatory therapy (IT),4 although formal trials are lacking. We present a multicenter, retrospective study to compare the outcome of patients who were treated with t-MCS and IT vs. patients who didn’t receive these treatments. We included patients with the diagnosis of FM based on the presence of viral prodromal signs/symptoms followed by acute onset of severe heart failure (HF) without other relevant differential diagnosis or pre-existing cardiac disorders. Patients who received both t-MCS and IT during hospitalization were classified as t-MCS+IT group. | Ning Zhou Yuhua Zhao Jiangang Jiang Lan Shen Junming Li Jing Wan Xueping Ma Jing Zhang Enrico Ammirati Dao Wen Wang | 2021 | Signal Transduction and Targeted Therapy2021，6，11： | 14 |
| 9 | WDR26 promotes mitophagy of cardiomyocytes induced by hypoxia through Parkin translocation显示文摘心肌的局部缺血是血流动的减小引起到心的一个心条件,阻止心收到足够的氧。心肌的局部缺血全球性是死亡的最普通的原因。心 ischemic preconditioning (欧洲电脑生产厂商) 对局部缺血和 ischemia-reperfusion 损害导致的心肌的房间死亡有保护的效果。WDR26 最近作为蛋白质被识别了被增加后面的老鼠心脏的欧洲电脑生产厂商。WDR26 能支持 H9c2 房间的增长并且通过禁止 apoptosis.?However 保护 cardiomyocytes 免于氧化应力,它在心肌的局部缺血的角色是不清楚的。这研究的目的是在心肌的局部缺血和 H9c2 房间组织缺氧探索 WDR26 的角色。我们的结果证明 WDR26 被心肌的局部缺血和 H9c2 房间组织缺氧导致。WDR26 通过禁止保护 H9c2 房间免于组织缺氧损害 ? LDH 版本和增加的房间生存能力。WDR26 在 H9c2 房间的组织缺氧支持导致组织缺氧的 autophagy。我们进一步证明在 H9c2 房间组织缺氧, WDR26 增加 mitochondrial 膜潜力,从而线粒体的增加 Parkin translocation。在 Parkin 是在线粒体的 translocated 以后, WDR26 能在 H9c2 房间的组织缺氧增加 mitochondrial 蛋白质 ubiquitination。WDR26 是对组织缺氧的反应的一个调停人,并且 WDR26 在调停组织缺氧的 autophagy 和 mitophagy 起一个重要作用。这研究在组织缺氧期间在 cardiomyocyte 损害提供新奇卓见进 WDR26 的保护的角色。WDR26 可以为心肌的局部缺血的处理用作一个潜在的目标。 | Yansheng Feng Jia Zhao Huifang Hou Hui Zhang Yunjuan Jiao Jiangang Wang Yongling Wang Yinping Sun | 2016 | Acta Biochimica et Biophysica Sinica2016，48，12： | 13 |
| 10 | High cadmium pollution risk on vegetable amaranth and a selection for pollution-safe cultivars to lower the risk显示文摘一个壶实验被种蔬菜苋的 29 不同遗传型(Amaranthus spp ) 在下面执行低 --(0.12 mg 椠 ?? 牧潯敶吗? | YihuiZHOU Meng XUE Zhongyi YANG Yulian GONG Jiangang YUAN Chunyan ZHOU Baifei HUANG | 2013 | Frontiers of Environmental Science & Engineering2013，7，2： | 10 |
| 11 | Urban Spatial Restructuring in Transitional Economy——Changing Land Use Pattern in Shanghai显示文摘For almost three decades, China has been undergoing significant transition from a planned economy to a market economy. Fast-paced economic growth and urbanization, interacting with market-oriented reforms in land re- sources allocation, have caused profound spatial restructuring of Chinese cities. This paper examines urban expansion and land use reconfiguration in Shanghai’s central city from 1979 to 2002, with a special focus on the effect of the adoption of the land-leasing system in 1988. The empirical research, which employs GIS-based spatial analysis tech- niques to explore land use data for multiple years, indicates fundamental changes in the spatial characteristics of urban development in Shanghai after this important land policy reform. | XU Jiangang LIAO Banggu SHEN Qing ZHANG Feng MEI Anxin | 2007 | Chinese Geographical Science2007，17，1： | 10 |
| 12 | Temporal echocardiography findings in patients with fulminant myocarditis: beyond ejection fraction decline显示文摘The features of myocardial strains from speckle-tracking echocardiography (STE) have not been well defined in fulminant myocarditis (FM) patients.In this study,changes in the left ventricular ejection fraction (LVEF) and global and layer-specific myocardial strains over time were monitored.We aimed to determine the echocardiographic patterns of FM and ascertain their significance in FM treatment.Twenty patients who were clinically diagnosed with FM and received mechanical life support were prospectively enrolled.Conventional echocardiographic measurements were obtained,and serial strain echocardiography was performed from admission to hospital discharge until LVEF recovery (> 50%).Global/regional peak systolic longitudinal strains (GLS/RLS) and layer-specific longitudinal strains were quantified,and their changes with time were monitored in 14 FM patients.All patients had severely impaired cardiac function.Steep improvement in LVEF and GLS were observed within 6 days.Layer-specific strain analysis showed that reduction at admission or recovery at discharge in the endocardium and epicardium strains were equal.In conclusion,FM patients who received mechanical circulatory supports exhibited steep improvement in ventricular function within 6 days.The patchy and diffused distribution pattern of reduced RLS and equally and severely impaired strain in the endocardium and epicardium are valuable features in the diagnosis of FM. | Houjuan Zuo Rui Li Fei Ma Jiangang Jiang Kun Miao Haojie Li Eike Nagel Marijana Tadic Hong Wang Dao Wen Wang | 2020 | Frontiers of Medicine2020，14，3： | 10 |
| 13 | Genotype variations in accumulation of cadmium and lead in celery (Apium graveolens L.) and screening for low Cd and Pb accumulative cultivars显示文摘To help reduce risks of heavy metal pollution, two pot experiments were conducted to investigate the variations, transfer potential, and stability of Cadmium (Cd) and Lead (Pb) accumulations in celery (Apium graveolens L.) and to screen for low Cd and Pb accumulative cultivars. The maximum differences in shoot Cd concentration were 4.7-fold under low-Cd exposure and 3.3-fold under high-Cd exposure. These genotype variations in Cd accumulation are sufficiently large to help reduce Cd contamination risk in soil by using the Low-Cd-Accumulative genotypes. Cd accumulation of the Low-Cd-Accumulative genotypes is significantly positive correlated with Pb accumulation. Evidence obtained proves that Cd and Pb accumulations in celery are stable and genotype-dependent at the cultivar level. The presence of high-Pb contamination in soil promoted Cd accumulation in shoots of celery. Celery is considered a species with high risks in Cd pollution and low risks in Pb pollution. Among the tested cultivars, cv. Shuanggang- kangbing (SGKB) had the lowest shoot Cd and Pb accumulating abilities, and thus is the most important material for breeding of pollution-safe cultivars (PSCs) to minimize Cd and Pb accumulations in celery. | Kun ZHANG Jianbing WANG Zhongyi YANG Guorong XIN Jiangang YUAN Junliang XIN Charlie HUANG | 2013 | Frontiers of Environmental Science & Engineering2013，7，1： | 9 |
| 14 | Spatio-temporal Pattern Characteristics of Relationship Between Urbanization and Economic Development at County Level in China显示文摘The relationship between China’s urbanization and economic development(RCUED) is an important concern nationwide. As important actors in regional strategy and policy, county-level regions have played an increasingly significant role in the development of China’s social economy. However, the existing research on the RCUED lacks the fine depiction of the county-level administrative units.Using 2000 and 2010 census data and the statistical analysis method, we uncovered the evolution characteristics of China’s urbanization and economic development and conducted a quantitative identification for the RCUED with improved methods using the quadrant map approach. In addition, we investigated the spatial correlation effect of the RCUED using the spatial autocorrelation analysis method. The results were as follows: 1) In general, a high degree of matching exists between China’s urbanization and economic development at the county level at the significance level of 0.01. The correlation coefficients between China’s urbanization and economic development in2000 and 2010 were 0.608 and 0.603, respectively. 2) A significant regional difference exists in the RCUED at the county level. Based on a comparative analysis of 2276 county units in China in the two years, we found that county units can be categorized as under-urbanized, basic coordination and over-urbanized in various areas. No situation was observed where urbanization seriously lagged behind the economic development level, so the levels of urbanization and economic development appear to be basically coordinated,and the coordination state may be gradually optimized over time. 3) Over time, the spatial dependency of the RCUED has weakened and the spatial heterogeneity has increased. Northeast China has always been an area characterized by over-urbanization. The number of county units classified as under-urbanized has begun to decline in eastern coastal urban agglomeration areas, while counties rich in resources have transformed from having point-shaped over-urbanization to plane-shaped under-urbanization along the northern border,and the number of over-urbanized county units has increased in the middle reaches of the Yangtze River. 4)’Lag-lag’ type and ’advance-advance’ type accounted for 68% of all counties in China, and these counties were shown to have obvious spatial differentiation characteristics. | YANG Zhen ZHANG Xiaolei LEI Jun DUAN Zuliang LI Jiangang | 2019 | Chinese Geographical Science2019，29，4： | 9 |
| 15 | Meteor radar observation of circulation near mesopause over Wuhan显示文摘The Wuhan meteor radar is the first all-sky meteor radar in China. The circulation near the mesopause from February to September 2002 is studied based on the data obtained by the Wuhan meteor radar. The zonal wind is usually eastward in winter from 80 to 100 km. The mean zonal wind become westward from March to early of May, when the winter circulation reverses to the summer circulation. But at the meteor heights, the zonal circulation usually becomes eastward after the middle of May. The meridional circulation is always equatorward. The peaks of the meridional wind move downward with the height, and the peak value reaches its maximum of 21 ms-1 in July. Having made a comparison between monthly mean wind and HWM93 model wind, the value of southward wind, the maximal value of eastward wind as well as the reversal height of zonal wind are found to be quite different from each other. | XIONG Jiangang, WAN Weixin, NING Baiqi & LIU Libo Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, China Correspondence should be addressed to Xiong Jiangang (e-mail: xjg@wipm.ac.cn) | 2003 | Chinese Science Bulletin2003，48，15： | 8 |
| 16 | Elabela, a new endogenous ligand of APJ, functions in embryos and adults organisms显示文摘 | Liqun Lu Jiangang Cao Lanfang Li Linxi Chen | 2017 | Acta Biochimica et Biophysica Sinica2017，49，4： | 7 |
| 17 | Coordination of Urbanization and Water Ecological Environment in Shayinghe River Basin,China显示文摘During the rapid industrialization and urbanization of China,urban agglomeration in river basin areas raises the problems of over-use of water resources and pollution of the water environment.Related research in China has mainly focused on the conflicts among economic growth,urban expansion and water resource shortages within admin-istrative boundaries.However,water environments are much more dependent on their physical boundaries than their administrative boundaries.Consistent with the nature of water environment,this study aims at analyzing coordination relationships between urban development and water environment changes within physical river basin boundaries.We chose the Shayinghe River Basin,China,as our case study area which is facing serious challenges related to water en-vironment protection.Then we classified 35 county-level administrative units into upstream,midstream and down-stream regions based on their physical characteristics;analyzed the coordination degree of urban agglomeration using the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) method;and constructed cooperative models using the Linear Programming (LP function) to simulate four scenarios of the coordination relationship be-tween urban population increase and water environment protection based on existing water resources and water pollu-tion data.The results show that the present coordinative situation in Shayinghe River Basin is not sustainable.In gen-eral,more than 50% administrative units are in the bad coordinative situation.In particular,the downstream region is under worse condition than the upstream and midstream regions.Cooperative models in scenario analyses indicate that the population scale set in existing urban master plannings is not coordinated with the water environment protection.To reach the goal of regional sustainable development,the total population needs to be controlled such that it will re-main at 4.5×10 7 or below by 2020 given the capacity of water environment. | ZHANG Xiang HU Hong XU Jiangang YIN Haiwei | 2011 | Chinese Geographical Science2011，21，4： | 7 |
| 18 | Decreased serum albumin level indicates poor prognosis of COVID-19 patients: hepatic injury analysis from 2,623 hospitalized cases显示文摘Coronavirus disease 2019(COVID-19) is a global pandemic which has caused numerous deaths worldwide. The present study investigated the roles of hypoproteinemia in the clinical outcome and liver dysfunction of COVID-19 patients. In this retrospective study, we extracted data from 2,623 clinically confirmed adult COVID-19 patients(≥18 years old) between January 29,2020 and March 6, 2020 in Tongji Hospital, Wuhan, China. The patients were divided into three groups—non-critically ill,critically ill, and death groups—in accordance with the Chinese Clinical Guideline for COVID-19. Serum albumin, low-density lipoproteins cholesterol(LDL-C), and high-density lipoproteins cholesterol(HDL-C) concentrations and inflammatory cytokines levels were measured and compared among these three groups. The median age of these 2,623 patients was 64 years old(interquartile range(IQR), 52–71). Among the patients enrolled in the study, 2,008(76.6%) were diagnosed as non-critically ill and 615(23.4%) were critically ill patients, including 383(14.6%) critically ill survivors and 232(8.8%) critically ill deaths in the hospital. Marked hypoalbuminemia occurred in 38.2%, 71.2%, and 82.4% patients in non-critically ill, critically ill, and death groups, respectively, on admission and 45.9%, 77.7%, and 95.6% of these three groups, respectively, during hospitalization. We also discovered that serum low-density lipoprotein(LDL) and HDL levels were significantly lower in critically ill and death groups compared to non-critically ill group. Meanwhile, the patients displayed dramatically elevated levels of serum inflammatory factors, while a markedly prolonged activated partial thromboplastin time(APTT) in critically ill patients reflected coagulopathy. This study suggests that COVID-19-induced cytokine storm causes hepatotoxicity and subsequently critical hypoalbuminemia, which are associated with exacerbation of disease-associated inflammatory responses and progression of the disease and ultimately leads to death for some critically ill patients. | Wei Huang Chenze Li Zhiquan Wang Hong Wang Ning Zhou Jiangang Jiang Li Ni Xin A.Zhang Dao-Wen Wang | 2020 | Science China(Life Sciences)2020，63，11： | 7 |
| 19 | NiPS_(3)quantum sheets modified nitrogen-doped mesoporous carbon with boosted bifunctional oxygen electrocatalytic performance显示文摘Electrocatalysts for oxygen reduction reactions(ORR)and oxygen evolution reactions(OER)are highly crucial and challenging toward the energy storage and conversion technologies such as fuel cells,metal-air batteries and water electrolysis.To replace noble-metal based catalysts and boost catalytic performance of carbon-based materials,we initially develop the nickel,phospho rus,sulfur and nitrogen co-modified mesoporous carbon(NiPS_(3)@NMC)as a bifunctional oxygen electrocatalyst.The perfo rmance for ORR(half-wave potential at 0.90 V)and OER(10 mA cm^(-2)at 1.48 V)surpasses those of Pt/C coupled with IrO_(2)catalysts and most of the non-precious metal based bifunctional electrocatalysts reported in related literature.Moreover,the electrochemical durability is also confirmed by accelerated durability tests(ADTs)and long-term chronoamperometry(CA)tests.We demonstrated that the interfacial effect between NiPS_(3)quantum sheets(QS s)and NMC substrates by thermal activation contributed to the enhanced oxygen electrode bifunctionality with more active sites,due to the electrons-donating from nickel,phosphorus and sulfur elements and relatively enriched pyridinic type N.Such excellent overall performance highlights the potential application of NiPS3 QSs and NMC composites as the materials on energy conversion and storage. | Kai Huang Yuyang Xu Yanpeng Song Ruyue Wanga Hehe Wei Yuanzheng Long Ming Lei Haolin Tang Jiangang Guo Hui Wu | 2021 | Journal of Materials Science & Technology2021，，6： | 7 |
| 20 | The study on county accessibility in China: Characteristics and effects on population agglomeration显示文摘这份报纸计算了所有县的空间可接近性(城市,城市的区域) 在有费用的中国加权的距离方法。县可接近性的区域部门被进行,并且交通可接近性的关系和人口聚集在这份报纸被讨论。结果显示在中国的县可接近性有主要低的价值和圆层和 reverse-to-natural 坡度的分发结构。在中国在县可接近性和人口密度之间有明显的关联。与这些分析,处于不同交通条件和区域类型的人口移植的内部机制被表明,并且能提供有用建议到地区性的计划,交通计划和在中国的人的聪明的分发。 | WANG Zhenbo XU Jiangang FANG Chuanglin XU Lu QI Yi | 2011 | Journal of Geographical Sciences2011，21，1： | 6 |
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