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| 1 | A Multicentre Prospective Evaluation of the Impact of Renal Insufficiency on In-hospital and Long-term Mortality of Patients with Acute ST-elevation Myocardial Infarction显示文摘 | Chao Li Dayi Hu Xubo Shi Li Li Jingang Yang Li Song Changsheng Ma | 2015 | Chinese Medical Journal2015，，1： | 18 |
| 2 | Fast acquisition of 3D images in a modified optical microscope based on integral imaging显示文摘This paper introduces a new technique of fast acquiring 3D information in microscope based on integral imaging. Experimental results prove that the proposed method has advantageous properties including simple configuration, no requirement of coherent light source and real-time 3D imaging information acquisition. This technique has an important prospect on optical microscopy and 3D display. | DAI ZhiHua WANG JinGang ZHAO Xing YANG Yong BU Jing YUAN XiaoCong | 2012 | Science China(Technological Sciences)2012，55，4： | 7 |
| 3 | RAPD Analysis of M_1 Generation of Gladiolus hybridus Hort Treated by EMS显示文摘Gladiolus hybridus Hort is one of the world's famous cutting flowers. It is very popular because of the big size, bright color, various shape, and long period of bloom. New species should be cultivated in order to meet the consumers' need of asking for the new. Among the technologies of cultivating new species of flowers, mutagenic breeding is a shortcut. This study treated corm bud of G. hybridus Hort with EMS of different consistency. Then M1 after treated was analyzed by RAPD. The result showed that EMS was a very effective mutagenic agent for the corm bud of G. hybridus Hort. With the increase of consistency, the mutagenic range increased first, then decreased, among which 0.6% EMS treatment had the biggest influence. However, with the same EMS consistency, there was not close relevancy between the amount of mutagenic agent and the divergence of plant's genomes, which offered a molecular basis for selecting plants with good mutation. | WANG Jingang GUO Ying CHE Daidi LIU Shenkui YANG Chuanpin | 2009 | Journal of Northeast Agricultural University(English Edition)2009，16，1： | 6 |
| 4 | WSe2 2D p-type semiconductor-based electronic devices for information technology:Design,preparation,and applications显示文摘The pioneering exfoliation of monolayer tungsten diselenide has greatly inspired researchers toward semiconducting applications.WSe2 belongs to a family of transition-metal dichalcogenides.Similar to graphene,WSe2 and analogous dichalcogenides have layered structures with weak van der Waals interactions between two adjacent layers.First,the readers are presented with the fundamentals of WSe2,such as types,morphologies,and properties.Here,we report the characterization principles and practices such as microscopy,spectroscopy,and diffraction.Second,the methods for obtaining high-quality WSe2,such as exfoliation,hydrothermal and chemical vapor deposition,are briefly listed.With advantages of light weight,flexibility,and high quantum efficiency,2D materials may have a niche in optoelectronics as building blocks in p-n junctions.Therefore,we introduce a state-of-the-art demonstration of heterostructure devices employing the p-type WSe2 semiconductor.The device architectures include field-effect transistors,photodetectors,gas sensors,and photovoltaic solar cells.Due to its unique electronic,optical,and energy band properties,WSe2 has been increasingly investigated due to the conductivity of the p-type charge carrier upon palladium contact.Eventually,the dynamic research on WSe2 and van der Waals heterostructures is summarized to arouse the passion of the 2D research community. | Qilin Cheng Jinbo Pang Dehui Sun Jingang Wang Shu Zhang Fan Liu Yuke Chen Ruiqi Yang Na Liang Xiheng Lu Yanchen Ji Jian Wang Congcong Zhang Yuanhua Sang Hong Liu Weijia Zhou | 2020 | InfoMat2020，2，4： | 5 |
| 5 | Spinel LiNi0.5Mn1.5O4 cathode ion batteries: Nano vs micro, disordered phase (F4332) for rechargeable lithium- ordered phase (P433m)显示文摘 | Jingang Yang Xiaopeng Han Xiaolong Zhang Fangyi Cheng Jun Chen | 2013 | Nano Research2013，6，9： | 5 |
| 6 | Cloning and Analysis of Full-Length cDNA of PumNPR1 Gene from Pyrus ussuriensis Maxim显示文摘The purpose of this study is to find a new gene resource for the researches of molecular breeding of Rosaceae plants disease-resistance.Pyrus ussuriensis Maxim is used as a starting material to clone the full-length cDNA of NPR1(nonexpressor of pathogenesis-related genes 1) which is a key regulator in SA(salicylic acid)-mediated systemic acquired resistance(SAR) by homologous cloning and RACE techniques.The length of the cDNA sequence was 1 767 bp,the ORF was 1 761 bp,it coded 586 amino acids,pI=5.58,the relative molecular weight was 65.009 ku,contained 19 kinds of amino acids,and had full BTB/POZ and ANK domains.Compared the homology of NPR1 gene in GenBank database,the homology with Pyrus pyrifolia,Arabidopsis thaliana,Nicotiana tabacum,Lycopersicon esculentum,Oryza sativa,Helianthus annuus were 98%,62%,68%,65%,57%,63%.The homology of functional area were 99%,78%,82%,79%,74%,77%.This NPR1 gene was considered as homologic gene of Pyrus ussuriensis Maxim and named PumNPR1. | CHE Daidi FAN Jinping WANG Jingang XU Ping YANG Tao LIU Shenkui | 2008 | Journal of Northeast Agricultural University(English Edition)2008，15，2： | 2 |
| 7 | Applications of nanogenerators for biomedical engineering and healthcare systems显示文摘The dream of human beings for long living has stimulated the rapid development of biomedical and healthcare equipment.However,conventional biomedical and healthcare devices have shortcomings such as short service life,large equipment size,and high potential safety hazards.Indeed,the power supply for conventional implantable device remains predominantly batteries.The emerging nanogenerators,which harvest micro/nanomechanical energy and thermal energy from human beings and convert into electrical energy,provide an ideal solution for self-powering of biomedical devices.The combination of nanogenerators and biomedicine has been accelerating the development of self-powered biomedical equipment.This article first introduces the operating principle of nanogenerators and then reviews the progress of nanogenerators in biomedical applications,including power supply,smart sensing,and effective treatment.Besides,the microbial disinfection and biodegradation performances of nanogenerators have been updated.Next,the protection devices have been discussed such as face mask with air filtering function together with real-time monitoring of human health from the respiration and heat emission.Besides,the nanogenerator devices have been categorized by the types of mechanical energy from human beings,such as the body movement,tissue and organ activities,energy from chemical reactions,and gravitational potential energy.Eventually,the challenges and future opportunities in the applications of nanogenerators are delivered in the conclusive remarks. | Wanli Wang Jinbo Pang Jie Su Fujiang Li Qiang Li Xiaoxiong Wang Jingang Wang Bergoi Ibarlucea Xiaoyan Liu Yufen Li Weijia Zhou Kai Wang Qingfang Han Lei Liu Ruohan Zang Mark HRümmeli Yang Li Hong Liu Han Hu Gianaurelio Cuniberti | 2022 | InfoMat2022，4，2： | 2 |
| 8 | Light-driven single-cell rotational adhesion frequency assay显示文摘The interaction between cell surface receptors and extracellular ligands is highly related to many physiological processes in living systems.Many techniques have been developed to measure the ligand-receptor binding kinetics at the single-cell level.However,few techniques can measure the physiologically relevant shear binding affinity over a single cell in the clinical environment.Here,we develop a new optical technique,termed single-cell rotational adhesion frequency assay(scRAFA),that mimics in vivo cell adhesion to achieve label-free determination of both homogeneous and heterogeneous binding kinetics of targeted cells at the subcellular level.Moreover,the scRAFA is also applicable to analyze the binding affinities on a single cell in native human biofluids.With its superior performance and general applicability,scRAFA is expected to find applications in study of the spatial organization of cell surface receptors and diagnosis of infectious diseases. | Yaoran Liu Hongru Ding Jingang Li Xin Lou Mingcheng Yang Yuebing Zheng | 2022 | eLight2022，2，1： | 2 |
| 9 | Ultrafine Grain Tungsten Heavy Alloys with Excellent Performance Prepared by Spark Plasma Sintering显示文摘Ultrafine grain tungsten heavy alloys (WHAs) were successfully produced from the nano-crystalline powders using spark plasma sintering.The present study mainly discussed the effects of sintering temperature on the density,microstructure and mechanical properties of the alloys.The relative density of 98.12% was obtained at 1 050 ℃,and the tungsten grain size is about 871 nm.At 1 000 ℃-1 200 ℃,the mechanical properties of the alloys tend to first rise and then goes down.After SPS,the alloy exhibits improved hardness (84.3 HRA at 1 050 ℃) and bending strength (987.16 MPa at 1 100 ℃),due to the ultrafine-grained microstructure.The fracture mode after bending tests is mainly characterized as intergranular or intragranular fracture of W grains,interfacial debonding of W grains-binding phase and ductile tearing of binding phase.The EDS analysis reveals a certain proportion of solid solution between W and Ni-Fe binding phase.The good mechanical properties of the alloys can be attributed to grain refinement and solid solution strengthening. | ZHANG Jingang WANG Weimin JI Wei HE Qianglong WANG Aiyang TAN Lin YANG Kai | 2020 | Journal of Wuhan University of Technology(Materials Science)2020，35，2： | 2 |
| 10 | Mechanism of improving skin barrier function in a mouse model of atopic dermatitis using Mahuang Lianqiao Chixiaodou decoction and its disassembled formula显示文摘Objective: To reveal the mechanism of Mahuang Lianqiao Chixiaodou decoction and its disassembled formula for improving the skin barrier function in a mouse model of atopic dermatitis(AD).Methods: Sixty specific-pathogen free male BALB/c mice were randomly divided into the control group,model group, whole formula group(WF), exterior-releasing formula group(ERF), interior-clearing formula group(ICF), and positive control group(PC). A mouse model of AD was established using the semiantigen 2,4-dinitrofluorobenzene induction method. The lesion scores, transepidermal water loss and p H, and skin histopathology of mice in each group were observed. The expressions of filaggrin, loricrin,and involucrin were detected by the streptavidin peroxidase immunohistochemical method and western blotting, and their mRNA expressions were detected by quantitative polymerase chain reaction.Results: Mice in the WF, ERF, ICF, and PC groups showed reduced skin lesion performance, improved histopathology, decreased skin lesion score, transepidermal water loss and pH, and upregulated expressions of proteins including filaggrin, loricrin, and involucrin, and their mRNAs. The most obvious regulatory effect was observed in the WF group, followed by the ICF, ERF, and PC groups, accordingly.Conclusions: Mahuang Lianqiao Chixiaodou decoction and its disassembled formula can improve the skin barrier function in a mouse model of AD by upregulating filaggrin, loricrin, and involucrin, and their mRNA expressions, and the most optimal effect was noted in the WF group, followed by the ICF and ERF groups, which suggests that the effect of clearing heat and resolving dampness in improving the skin barrier function of AD is more obvious and is one of the key treatments for AD. | Jingang Liu Yan Sun Huimin Yuan Yuda Li Jing Feng Yushan Gao Yang Tang Shujing Zhang Hang Wang Fengjie Zheng | 2021 | Journal of Traditional Chinese Medical Sciences2021，8，4： | 2 |
| 11 | Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury显示文摘Compelling evidence has revealed that biased activation of G protein-coupled receptor(GPCR)signaling,including angiotensin II(AngII)receptor type 1(AT1)signaling,plays pivotal roles in vascular homeostasis and injury,but whether a clinically relevant endogenous biased antagonism of AT1 signaling exists under physiological and pathophysiological conditions has not been clearly elucidated.Here,we show that an extracellular matrix protein,cartilage oligomeric matrix protein(COMP),acts as an endogenous allosteric biased modulator of the AT1 receptor and its deficiency is clinically associated with abdominal aortic aneurysm(AAA)development.COMP directly interacts with the extracellular N-terminus of the AT1 via its EGF domain and inhibits AT1-β-arrestin-2 signaling,but not Gq or Gi signaling,in a selective manner through allosteric regulation of AT1 intracellular conformational states.COMP deficiency results in activation of AT1a-β-arrestin-2 signaling and subsequent exclusive AAA formation in response to AngII infusion.AAAs in COMP–/–or ApoE–/–mice are rescued by AT1a orβ-arrestin-2 deficiency,or the application of a peptidomimetic mimicking the AT1-binding motif of COMP.Explorations of the endogenous biased antagonism of AT1 receptor or other GPCRs may reveal novel therapeutic strategies for cardiovascular diseases. | Yi Fu Yaqian Huang Zhao Yang Yufei Chen Jingang Zheng Chenfeng Mao Zhiqing Li Zhixin Liu Bing Yu Tuoyi Li Meili Wang Chanjuan Xu Yiwei Zhou Guizhen Zhao Yiting Jia Wei Guo Xin Jia Tao Zhang Li Li Ziyi Liu Shengchao Guo Mingliang Ma Heng Zhang Bo Liu Junbao Du Wengong Wang Chaoshu Tang Pei Gao Qingbo Xu Xian Wang Jianfeng Liu Jinpeng Sun Wei Kong | 2021 | Cell Research2021，31，7： | 2 |
| 12 | Atomic oxygen-resistant and transparent polyimide coatings from [3,5-bis(3-aminophenoxy)phenyl]diphenylphosphine oxide and aromatic dianhydrides: Preparation and characterization显示文摘 | Zhuo Li Haiwang Song Minhui He Jingang Liu Shiyong Yang | 2012 | Progress in Organic Coatings (-)2012，，1： | 2 |
| 13 | The evolution of China’s regulation of agricultural biotechnology显示文摘To ensure safe use of genetically modified organisms(GMOs),since 1993,China has made great efforts to establish and improve the safety regulatory system for GMOs.Here,we summarize and analyze the regulatory framework of agricultural GMOs,and the progress in regulatory approval of GM crops in China.In general,the development of GMO safety regulations underwent four stages:exploration(1993–2000),development(2001–2010),improvement(2011–2020)and current(2021-present)stage.The first formal regulation was promulgated in 1993,which provided a basis for further development of the regulations,during the exploration stage,when insect-resistant GM cotton,expressing genes from Bacillus thuringiensis(Bt),was approved for cultivation.During the development stage,the Chinese government issued a series of administrative measures,which covered almost all the fields relative to GMO safety when the basic regulatory system was established.Along with the controversy over GMO safety,the regulations have been further,and greatly improved,during improvement stage.From 2021,a few additional revisions have been made,and meanwhile,the new regulation on gene-edited crops was introduced with the development of biotechnology,forming a relative complete regulation and law system for China.The well-developed GMO regulations establishes a firm basis for safe use of GM crops in China.Currently,GM cotton and GM papaya have been widely grown on a large scale in China that have brought great economic and ecological benefits.In addition,12 corn events,3 soybean events,and 2 rice events have also obtained biosafety certification,but presently,these lines have yet to enter commercial production.However,several GM soybean and corn events have entered pilot industrialization,and can soon be expected to be commercially grown in China.In addition to planting,six GM crops,including soybean,corn,cotton,canola,papaya and sugar beet,with a total of 64 events,have been approved for import as processing material in China. | Jingang Liang Xiaowei Yang Yue Jiao Danxia Wang Qiang Zhao Yu Sun Yunhe Li Kongming Wu | 2022 | aBIOTECH2022，3，4： | 2 |
| 14 | Atomic oxygen-resistant and transparent polyimide coatings from [3,5-bis(3-aminophenoxy)phenyl]diphenylphosphine oxide and aromatic dianhydrides: Preparation and characterization显示文摘 | Zhuo Li Haiwang Song Minhui He Jingang Liu Shiyong Yang | 2012 | Progress in Organic Coatings (-)2012，，1： | 1 |
| 15 | Synthesis and characterization of novel soluble fluorinated aromatic polyamides derived from fluorinated isophthaloyl dichlorides and aromatic diamines显示文摘 | Ziyi Ge Shiyong Yang Zhiqiang Tao Jingang Liu Lin Fan | 2004 | Polymer2004，，11： | 1 |
| 16 | 显示文摘 | Yang Jingang Cheng Fangyi Liang Jing | 2011 | Interna- tional Journal of Hydrogen Energy2011，36，2： | 1 |
| 17 | Synthesis and characterization of novel fluorinated polyimides derived from 4,4'- diphthalic anhydride and aromatic diamines 显示文摘 | Hongshen Li Jingang Liu Kai Wang Lin Fan Shiyong Yang | 2006 | Polymer2006，47，4： | 1 |
| 18 | MicroRNA-505 identified from patients with essential hypertension impairs endothelial cell migration and tube formation显示文摘 | Qinbo Yang Chenglin Jia Peiwei Wang Minqi Xiong Jingang Cui Li Li Wenjian Wang Qingyu Wu Yu Chen Teng Zhang | 2014 | International Journal of Cardiology2014，，： | 1 |
| 19 | Relationship between exciton recombination zone and applied voltage in organic light-emitting diodes显示文摘 | Hao Jingang Deng Zhenbo Yang Shengyi | 2006 | Displays2006，27，3： | 1 |
| 20 | 显示文摘 | Yang Jingang Zhang Xiaolong Zhu Zhiqiang | 2013 | Journal of Electroanalytical Chemistry2013，688，1： | 1 |
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