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| 1 | Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion显示文摘 | Zhenrui Li Pengxu Qian Wanqing Shao Hailing Shi Xi C. He Madelaine Gogol Zulin Yu Yongfu Wang Meijie Qi Yunfei Zhu John M. Perry Kai Zhang Fang Tao Kun Zhou Deqing Hu Yingli Han Chongbei Zhao Richard Alexander Hanzhang Xu Shiyuan Chen Allison Peak Kathyrn Hall Michael Peterson Anoja Perera Jeffrey S. Haug Tari Parmely Hua Li Bin Shen Julia Zeitlinger Chuan He Linheng Li | 2018 | Cell Research2018，28，9： | 18 |
| 2 | Chemical Compositions and Distribution Characteristics of Cements in Longmaxi Formation Shales, Southwest China显示文摘Shale gas resources have been regarded as a viable energy source, and it is of great significance to characterize the shale composition of different cements, such as quartz and dolomite. In this research, chemical analysis and the multifractal method have been used to study the mineral compositions and petrophysical structures of cements in shale samples from the Longmaxi Formation, China. X-ray diffraction, electron microprobe, field emission scanning electron microscopy, cathodoluminescence microscopy and C-O isotope analyses confirmed that cements in the Longmaxi Formation shales are mainly composed of Fe-bearing dolomite and quartz. Fe-bearing dolomite cements concentrate around dolomite as annuli, filling micron-sized inorganic primary pores. Quartz cements in the form of nanoparicles fill primary inter-crystalline pores among clay minerals. Theoretical calculation shows that the Fe-bearing dolomite cements formed slightly earlier than the quartz cements, but both were related to diagenetic illitization of smectite. Moreover, multifractal analysis reveals that the quartz cements are more irregularly distributed in pores than the Fe-bearing dolomite cements. These results suggest that the plugging effect of the quartz cements on the primary inoraganic pore structures is the dominant factor resulting in low interconnected porosity of shales, which are unfavorable for the enrichment of shale gas. | Wenda Zhou Shuyun Xie Zhengyu Bao Emmanuel John M. Carranza Lei Lei Zhenzhen Ma | 2019 | Journal of Earth Science2019，30，5： | 12 |
| 3 | The record of cultivated rice from archaeobiological evidence in northwestern China 5000 years ago显示文摘Pollen, plant seeds and phytoliths from an AMS dated sediment profile at the Xishanping site indicate that the cultivation of rice might start no later than 5070 cal. a BP in the region of Tianshui, Gansu Province. It continued from 5070 to 4300 cal. a BP. This is so far the oldest and the most northwestern record of cultivated rice in Neolithic China, which extends the known region of prehistoric rice cultivation at least 2° longitude to the west. This finding provides important evidence for reconstructing the cultivation region of rice at 5000 a BP (an important time period), and its spreading history in East Asia, during the Neolithic. | LI XiaoQiang ZHOU XinYing ZHANG HongBin ZHOU Jie SHANG Xue DODSON John | 2007 | Chinese Science Bulletin2007，52，10： | 11 |
| 4 | Early agricultural development and environmental effects in the Neolithic Longdong basin(eastern Gansu)显示文摘Neolithic agricultural development and environmental effects in the Longdong area were reconstructed using a synthetic approach,investigating pollen,charcoal,and seed remains for two cultural layer sections and five flotation sites.Results show that Neolithic agriculture in the Longdong area had a simple organization and was dominated by the production of common millet,especially in the early and middle Yangshao age.After the late Yangshao age,Neolithic agriculture developed into a more complex structure,dominated by both common and foxtail millet and the cultivation of rice and soybeans.The production of foxtail millet gradually increased through the Neolithic period,reaching its highest point during the Qijia culture.Soybeans were first cultivated during the late Yangshao culture,approximately 5000 cal a BP.Rice production began no later than 4800 cal a BP,and continued to exist in the Qijia culture,approximately 4000 cal a BP.Agricultural production in Neolithic Longdong,specifically in the 'Yuan' area of the loess plateau,developed as a shrub and grass dominated landscape.Vegetation in the river valleys was partly covered with Picea,Tusga,and Quercus coniferous and broadleaf mixed forests.Agricultural activity during the Neolithic period caused an increase in farmland on the loess tableland and a decrease in the abundance of shrub and grassland in the Longdong area.When farmlands were abandoned,vegetation recovered with Hippophae-,Rosaceae-,Ephedra-,and Leguminosae-dominated shrublands and Artemisia-dominated grasslands. | ZHOU XinYing LI XiaoQiang ZHAO KeLiang DODSON John SUN Nan YANG Qing | 2011 | Chinese Science Bulletin2011，56，8： | 10 |
| 5 | A buried Neolithic paddy soil reveals loss of microbial functional diversity after modern rice cultivation显示文摘It has been documented that human activities are causing the rapid loss of taxonomic, phylogenetic, genetic and functional diversity in soils. However, it remains unclear how modern intensive rice cultivation impacts the soil microbiome and its functionality. Here we examined the microbial composition and function differences between a buried Neolithic paddy soil and an adjacent,currently-cultivated paddy soil using high throughput metagenomics technologies. Our results showed that the currently cultivated soil contained about 10-fold more microbial biomass than the buried one. Analyses based on both 16S rRNA genes and functional gene array showed that the currently cultivated soil had significantly higher phylogenetic diversity, but less functional diversity than the buried Neolithic one. The community structures were significantly different between modern and ancient soils,with functional structure shifting towards accelerated organic carbon(C) degradation and nitrogen(N) transformation in the modern soils. This study implies that, modern intensive rice cultivation has substantially altered soil microbial functional structure, leading to functional homogenization and the promotion of soil ecological functions related to the acceleration of nutrient cycling which is necessary for high crop yields. | Yong-Guan Zhu Jian-Qiang Su Zhihong Cao Kai Xue John Quensen Guang-Xia Guo Yun-Feng Yang Jizhong Zhou Hai-Yan Chu James M.Tiedje | 2016 | Science Bulletin2016，61，13： | 10 |
| 6 | 声波激励的超小型纳机电系统磁电天线显示文摘当前的小型天线依赖于电磁波的谐振,因此天线的尺寸与电磁波波长相关。典型的天线尺寸大于波长的1/10,而进一步缩小天线尺寸在近十年来都是一个公开的挑战。介绍一种通过悬浮铁氧/压电薄膜异质结构的声波激励纳机械磁电天线。这种磁电天线通过其在声波谐振频率处的磁电效应接收和发射电磁波。磁电天线中的体声波激发铁磁薄膜的磁化振荡,产生电磁波的辐射;反之,天线感应电磁波的磁场,得到压电电压输出。这种磁电天线(尺寸仅为波长的千分之一)比现有小型天线的尺寸小1到2个数量级,但性能却没有降低,在便携式无线通信系统中具有很大的应用潜力。 | Tianxiang Nan Hwaider Lin Yuan Gao Alexei Matyushov Guoliang Yu Huaihao Chen Neville Sun Shengjun Wei Zhiguang Wang Menghui Li Xinjun Wang Amine Belkessam Rongdi Guo Brian Chen James Zhou Zhenyun Qian Yu Hui Matteo Rinaldi Michael E.McConney BrANDon M.Howe Zhongqiang Hu John G.Jones Gail J.Brown Nian Xiang Sun 张建强(翻译) 陈鼎鼎(审校) | 2017 | 通信对抗2017，36，4： | 8 |
| 7 | Old age security in rural China: there is a long way to go显示文摘 | DAI Bao-zhen ZHOU Lu-lin Y John Mei | 2013 | Chinese Medical Journal2013，，22： | 8 |
| 8 | A fundamental theorem for eco-environmental surface modelling and its applications显示文摘We propose a fundamental theorem for eco-environmental surface modelling(FTEEM) in order to apply it into the fields of ecology and environmental science more easily after the fundamental theorem for Earth’s surface system modeling(FTESM). The Beijing-Tianjin-Hebei(BTH) region is taken as a case area to conduct empirical studies of algorithms for spatial upscaling, spatial downscaling, spatial interpolation, data fusion and model-data assimilation, which are based on high accuracy surface modelling(HASM), corresponding with corollaries of FTEEM. The case studies demonstrate how eco-environmental surface modelling is substantially improved when both extrinsic and intrinsic information are used along with an appropriate method of HASM. Compared with classic algorithms, the HASM-based algorithm for spatial upscaling reduced the root-meansquare error of the BTH elevation surface by 9 m. The HASM-based algorithm for spatial downscaling reduced the relative error of future scenarios of annual mean temperature by 16%. The HASM-based algorithm for spatial interpolation reduced the relative error of change trend of annual mean precipitation by 0.2%. The HASM-based algorithm for data fusion reduced the relative error of change trend of annual mean temperature by 70%. The HASM-based algorithm for model-data assimilation reduced the relative error of carbon stocks by 40%. We propose five theoretical challenges and three application problems of HASM that need to be addressed to improve FTEEM. | Tianxiang YUE Na ZHAO Yu LIU Yifu WANG Bin ZHANG Zhengping DU Zemeng FAN Wenjiao SHI Chuanfa CHEN Mingwei ZHAO Dunjiang SONG Shihai WANG Yinjun SONG Changqing YAN Qiquan LI Xiaofang SUN Lili ZHANG Yongzhong TIAN Wei WANG Ying’an WANG Shengnan MA Hongsheng HUANG Yimin LU Qing WANG Chenliang WANG Yuzhu WANG Ming LU Wei ZHOU Yi LIU Xiaozhe YIN Zong WANG Zhengyi BAO Miaomiao ZHAO Yapeng ZHAO Yimeng JIAO Ufra NASEER Bin FAN Saibo LI Yang YANG John PWILSON | 2020 | Science China Earth Sciences2020，63，8： | 7 |
| 9 | Vegetation and Environment History for the Past 14 000 yr BP from Dingnan, Jiangxi Province, South China显示文摘迟了的 Pleistocene-Holocene 花粉,磷,和炭记录在南部的中国在南部的江西省从 peatland 被重建。今天的区域与米饭稻,蔬菜,和水果统治的村庄,小镇,和农业有一处多山、滚动的风景第二等的森林和松重新植林的花园,以及区域。记录在 14 300 年 BP 前开,与统治沼泽地区域的 Alnus 树林并且与包围斜坡上的开的 Quercus 树林。森林区域从约 12 800 年 BP 变得更复杂并且从 9 000 年 BP 进一步。在约 6 000 年 BP,有变清的证据,由 45004000 年 BP,在沼泽地 Alnus 和陆上的森林的完全的倒塌作为低区域被变换成米饭生产。为许多记录,在这个地点附近的火的出现是低的,尽管有地区性的火的证据。火在变清被用作一个工具然后在残株在米饭收获以后烧的年度周期使用了。营养素铺平,在沉积由全部的磷思考了似乎是仔细,与在表面的森林变化和高价值有关,层可能源于与农业联系的陆地管理技术。因此,人的影响极大地改变了森林盖子,火频率,和滋养的动力学;这为约 6 000 年 BP 是明显的然后加强向现代。 | John Richard Dodson Shirene Hickson Rachel Khoo Xiao-Qiang Li Jemina Toia Wei-Jian Zhou | 2006 | Journal of Integrative Plant Biology2006，48，9： | 7 |
| 10 | Quantitative diffusion-weighted magnetic resonance enterography in ileal Crohn’s disease: A systematic analysis of intra and interobserver reproducibility显示文摘BACKGROUND Magnetic resonance enterography(MRE) is increasingly attractive as a noninvasive and radiation-free tool for assessing Crohn’s disease(CD). Diffusionweighted imaging(DWI) is recommended as an optional MRE sequence for CD by the European Society of Gastrointestinal and Abdominal Radiology, and has shown a superb potential as a quantitative modality for bowel inflammation evaluation. However, the measurement reproducibility of quantitative DWI analysis in MRE has not been ascertained so far. To facilitate the application of quantitative diffusion-weighted MRE in the clinical routine, systematic investigations of the intra and interobserver reproducibility of DWI quantitative parameters should be performed.AIM To evaluate the intra and interobserver reproducibility of quantitative analysis for diffusion-weighted MRE(DW-MRE) in ileal CD.METHODS Forty-four subjects(21 with CD and 23 control subjects) who underwent ileocolonoscopy and DW-MRE(b = 800 s/mm2) within one week were included.Two radiologists independently measured apparent diffusion coefficients(ADC)of the terminal ileum and signal intensity ratio(SR) of the terminal ileum to ipsilateral psoas muscle on DWI images(b = 800 s/mm2). Between-and withinreader agreements were assessed using intraclass correlation coefficients(ICC),coefficients of variation(CoV), and 95% limits of agreement of Bland-Altman plots(BA-LA LoA). Diagnostic performances of ADC and SR for identifying inflamed terminal ileum from the normal were evaluated by receiver operating characteristic(ROC) curve analysis.RESULTS There were no significant differences in ADC or SR values between the two sessions or between the two radiologists either in the CD or control group(paired t-test, P > 0.05). The intra and interobserver reproducibility of ADC(ICC: 0.952-0.984;CoV: 3.73-6.28%;BA-LA LoA: ±11.27% to ±15.88%) and SR(ICC: 0.969-0.989;CoV: 3.51%-4.64%;BA-LA LoA: ±10.62% to ±15.45%) was excellent for CD.Agreement of ADC measurements was slightly less in control subjects(ICC:0.641-0.736;CoV: 10.47%-11.43%;BA-LA LoA: ± 26.59% to ± 30.83%). SR of normal terminal ileum demonstrated high intra and interobserver reproducibility(ICC: 0.944-0.974;CoV: 3.73%-6.28%;BA-LA LoA: ± 18.58% to ± 24.43%). ADC and SR of two readers had outstanding diagnostic efficiencies(area under the ROC curve: 0.923-0.988).CONCLUSION Quantitative parameters derived from DW-MRE have good to excellent intra and interobserver agreements with high diagnostic accuracy, and can serve as robust and efficient quantitative biomarkers for CD evaluation. | Hao Yu Ya-Qi Shen Fang-Qin Tan Zi-Ling Zhou Zhen Li Dao-Yu Hu John N Morelli | 2019 | World Journal of Gastroenterology2019，25，27： | 7 |
| 11 | Optimization of variables for maximizing efficacy and efficiency in aerial spray application to cotton using unmanned aerial systems显示文摘Aerial spraying can support efficient defoliation without crop contact.With the recent introduction to unmanned aerial system(UAS)for aerial spraying in China,there is a need to determine the optimum application variables to achieve high efficacy and efficiency with low costs.The present research involved field studies across two annual cotton production seasons in North Xinjiang,China.Four factors,including volume rate(A),tank mix including spray adjuvants(B),flight altitude(C),flight speed(D)and three levels of L9(3^(4))orthogonal arrays were carried out to optimize the application parameters for three types of UASs.These included different numbers of rotors as follows:four-rotors,six-rotors and eight-rotors.Spray coverage,distribution uniformity(coefficient of variation(CV)of droplet coverage),rates of cotton defoliation and boll opening,application efficiency and cost were measured and assessed.Results showed that:(1)the rates of defoliation and boll opening by aerial cotton defoliant application could meet the requirement of cotton mechanized harvesting;(2)the optimal scenario for the three UASs was A_(3)B_(2)C_(1)D_(3),Volume rate(A3):48 L/hm^(2);Tank mix and concentration(B_(2)):(Tuotulong 225+Sujie 750+Ethephon 2250)mL/hm^(2),Flight altitude(C_(1)):1.5 m,and Flight speeds(D_(3))for unmanned helicopters with four-rotors,six-rotors and eight-rotors were 3.12 m/s,2.51 m/s and 3.76 m/s,respectively.These results can provide guidance for cotton defoliant aerial spraying in China using UAS. | Juan Liao Ying Zang Xiwen Luo Zhiyan Zhou Yubin Lan Yu Zang Xiuyan Gu Weiming Xu Andrew John Hewitt | 2019 | International Journal of Agricultural and Biological Engineering2019，12，2： | 6 |
| 12 | Cell cycle-related kinase reprograms the liver immune microenvironment to promote cancer metastasis显示文摘The liver is an immunologically tolerant organ and a common metastatic site of multiple cancer types.Although a role for cancer cell invasion programs has been well characterized,whether and how liver-intrinsic factors drive metastatic spread is incompletely understood.Here,we show that aberrantly activated hepatocyte-intrinsic cell cycle-related kinase(CCRK)signaling in chronic liver diseases is critical for cancer metastasis by reprogramming an immunosuppressive microenvironment.Using an inducible liverspecific transgenic model,we found that CCRK overexpression dramatically increased both B16F10 melanoma and MC38 colorectal cancer(CRC)metastasis to the liver,which was highly infiltrated by polymorphonuclear-myeloid-derived suppressor cells(PMNMDSCs)and lacking natural killer T(NKT)cells.Depletion of PMN-MDSCs in CCRK transgenic mice restored NKT cell levels and their interferon gamma production and reduced liver metastasis to 2.7% and 0.7%(metastatic tumor weights)in the melanoma and CRC models,respectively.Mechanistically,CCRK activated nuclear factor-kappa B(NF-κB)signaling to increase the PMN-MDSC trafficking chemokine C-X-C motif ligand 1(CXCL1),which was positively correlated with liver-infiltrating PMN-MDSC levels in CCRK transgenic mice.Accordingly,CRC liver metastasis patients exhibited hyperaaivation of hepatic CCRK/NF-κB/CXCL1 signaling,which was associated with accumulation of PMN-MDSCs and paucity of NKT cells compared to healthy liver transplantation donors.In summary,this study demonstrates that immunosuppressive reprogramming by hepatic CCRK signaling undermines antimetastatic immunosurveillance.Our findings offer new mechanistic insights and therapeutic targets for liver metastasis intervention. | Xuezhen Zeng Jingying Zhou Zhewen Xiong Hanyong Sun Weiqin Yang Myth T.S.Mok Jing Wang Jingqing Li Man Liu Wenshu Tang Yu Feng Hector Kwong-Sang W ang Shun-Wa Tsang King-Lau Chow Philip Chun Yeung John Wong Paul Bo-San Lai Anthony Wing-Hung Chan Ka Fai To Stephen Lam Chan Qiang Xia Jing Xue Xiao Chen Jun Yu Sui Peng Joseph Jao-Yiu Sung Ming Kuang Alfred Sze-Lok Cheng | 2021 | Cellular & Molecular Immunology2021，18，4： | 5 |
| 13 | Ameliorative effects of potassium on drought-induced decreases in fiber length of cotton(Gossypium hirsutum L.) are associated with osmolyte dynamics during fiber development显示文摘Fiber length of cotton(Gossypium hirsutum L.)decreases under drought stress,potassium(K)could diminish the decreased caused by drought,but the mechanism associated with this alleviation effect is not clear.We evaluated the effect of K on fiber elongation using two cotton cultivars,Simian 3 and Siza 3,grown in well-watered and drought-stressed conditions.Potassium fertilizer(K2O)was applied 0,150,or 300 kg ha?1 in each growing condition.Drought stress reduced the final fiber length due to a decline in the maximum rate of rapid elongation(Vmax,mmday?1).The application of K alleviated the droughtinduced fiber length reduction by increasing Vmax.At 10 and 15 days post-anthesis(DPA),drought significantly reduced osmotic potential(OP)and increased K+and malate contents at all K rates,relative to well-watered conditions,which was associated with increased activities of phosphoenolpyruvate carboxylase(PEPC),V-ATPase,PPase,and PM H+-ATPase in cotton fiber.However,the relative contribution of K+and malate to OP declined under drought in comparison with well-watered condition.Compared with control without K,K application decreased OP and increased the accumulation of osmolytes(K+,malate and soluble sugar)as well as the activities of related enzymes in fiber irrespective of water treatments.Moreover,K application increased osmotic adjustment during drought,and improved the contribution of K+and malate to OP,especially under drought stress.This study showed that drought decreased fiber length by reducing Vmax,and K application ameliorates the decline in fiber elongation due to drought by enhancing osmolytes accumulation and their contribution to OP in fiber cells. | Wenqing Zhao Haoran Dong Rizwan Zahoor Zhiguo Zhou John L.Snider Yinglong Chen Kadambot H.M.Siddique Youhua Wang | 2019 | The Crop Journal2019，7，5： | 4 |
| 14 | Magnetic polarity ages of the fossil-bearing strata at the Sihetun section,West Liaoning:A preliminary result显示文摘Rock-magnetic and palaeomagnetic studies have been carried out on the interval of famous fossil-bearing sedimentary rocks and its overlying basalts and underlying basalts at the Sihetun section, West Liaoning Province. Normal polarity was obtained for the sedimentary interval and the underlying basalts, while reversed polarity was found in the overlying basalts. Taking account of the new 40Ar/39Ar ages (Swisher et al., 1999), we classified the fossil-bearing sedimentary interval into the Barremian M3n zone (Early Cretaceous age). Several abnormal horizons on magnetic properties, probably corresponding to the tuffs, were observed in the fossil-bearing sedimentary interval. This implies that the massive bio-extinction may link to dramatic environmental changes that were caused by volcanic eruptions. | PAN Yongxin ZHU Rixiang John Shaw ZHOU Yaoxiu | 2001 | Chinese Science Bulletin2001，46，17： | 4 |
| 15 | Morphological control of SnTe nanostructures by tuning catalyst composition显示文摘A method of controlling the morphology of SnTe nanostructures produced by a simple chemical vapor deposition is presented, in which Au-containing catalysts with different Au concentrations are used to induce specific growth behavior. Triangular SnTe nanoplates with a {100} dominated surface and {100}, {111} and {120} side facets were induced by AuSn catalysts, whereas 〈010〉 SnTe nanowires with four nonpolar {100} side-facets were produced using AusSn catalysts. Through detailed structural and chemical characterization, coupled with surface energy calculations, it is found that nanowire growth is thermodynamically controlled via a vapor-solid-solid growth mechanism, whereas nanoplate growth is kinetically controlled via a vapor-liquid-solid growth mechanism. Therefore, this study provides a fundamental understanding of the catalyst's role in the growth of IV-VI compound nanostructures. | Yichao Zou Zhigang Chen Jing Lin Xiaohao Zhou Wei Lu John Drennan Jin Zou | 2015 | Nano Research2015，8，9： | 4 |
| 16 | Trabecular Plate Loss and Deteriorating Elastic Modulus of Femoral Trabecular Bone in Intertrochanteric Hip Fractures显示文摘Osteoporotic hip fracture is associated with significant trabecular bone loss,which is typically characterized as low bone density by dual-energy X-ray absorptiometry(DXA)and altered microstructure by micro-computed tomography(μCT).Emerging morphological analysis techniques,e.g.individual trabecula segmentation(ITS),can provide additional insights into changes in plate-like and rod-like trabeculae,two major micro-structural types serving different roles in determining bone strength.Using ITS,we evaluated trabecular microstructure of intertrochanteric bone cores obtained from 23 patients undergoing hip replacement surgery for intertrochanteric fracture and 22 cadaveric controls.Micro-finite element(μFE)analyses were performed to further understand how the abnormalities seen by ITS might translate into effects on bone strength.ITS analyses revealed that,near fracture site,plate-like trabeculae were seriously depleted in fracture patients,but trabecular rod volume was maintained.Besides,decreased plate area and rod length were observed in fracture patients.Fracture patients also showed decreased elastic moduli and shear moduli of trabecular bone.These results provided evidence that in intertrochanteric hip fracture,preferential loss of plate-like trabeculae led to more rod-like microstructure and deteriorated mechanical competence adjacent to the fracture site,which increased our understanding of the biomechanical pathogenesis of hip fracture in osteoporosis. | Ji Wang Bin Zhou Ian Parkinson C.David L.Thomas John G.Clement Nick Fazzalari X.Edward Guo | 2013 | Bone Research2013，1，4： | 4 |
| 17 | Mutations around interferon sensitivity-determining region:A pilot resistance report of hepatitis C virus 1b in a Hong Kong population显示文摘AIM: To explore mutations around the interferon sensitivity-determining region (ISDR) which are associated with the resistance of hepatitis C virus 1b (HCV-1b) to interferon-α treatment. METHODS: Thirty-seven HCV-1b samples were ob- tained from Hong Kong patients who had completed the combined interferon-α/ribavirin treatment for more than one year with available response data. Nineteen of them were sustained virological responders, while 18 were non-responders. The amino acid sequences of the extended ISDR (eISDR) covering 64 amino acids upstream and 67 amino acids downstream from the previously reported ISDR were analyzed. RESULTS: One amino acid variation (I2268V, P = 0.023) was significantly correlated with treatment outcomein this pilot study with a limited number of patients, while two amino acid variations (R2260H, P = 0.05 and S2278T, P = 0.05) were weakly associated with treatment outcome. The extent of amino acid variations within the ISDR or eISDR was not correlated with treatment outcome as previously reported. CONCLUSION: Three amino acid mutations near but outside of ISDR may associate with interferon treatment resistance of HCV-1b patients in Hong Kong. | Xiao-Ming Zhou Paul KS Chan John S Tam | 2011 | World Journal of Gastroenterology2011，17，48： | 3 |
| 18 | Challenges and needs for China to eliminate rabies显示文摘In China,rabies is a significant public health concern where dogs remain the main reservoir of disease transmission to humans;rabies-related mortality ranks second in the world.We compiled all published articles and official documents on rabies in China's Mainland to examine challenges and needs to eliminate rabies in the country.The Chinese authorities have identified rabies as a priority,recognized rabies control in dogs as key to control rabies in humans and required intersectoral collaborations.Efforts have been made to respond effectively to the latest re-emergence of rabies,which peaked in 2007 with>3,300 cases.Despite these outcomes and the increasing volume of publications and regulations in the recent years,our review points to some major information gaps to improve rabies control activities and envisage elimination program.An emphasis on laboratory or pathogen-associated and basic epidemiology research in the literature has contrasted with the absence of information to monitor various systems in humans and animals(e.g.quality of surveillance,response and post-exposure prophylaxis).Information is also lacking to appropriately inform policymakers(e.g.economic disease burden,impact of policies)and assist program managers(e.g.comprehensive and strategic guidance for cost-effective prevention and control activities,public education and dog population management).In conclusion,strategic planning is needed to provide a sense of direction,demonstrate feasibility of elimination in China,and develop a research agenda,addressing country’s operational needs and constraints.The planning should be a multisectoral effort. | Wenwu Yin Jie Dong Changchun Tu John Edwards Fusheng Guo Hang Zhou Hongjie Yu Sirenda Vong | 2013 | Infectious Diseases of Poverty2013，2，1： | 3 |
| 19 | Poly(N,N-dimethylaminoethyl methacrylate) Grafted Poly(vinyl chloride)s Synthesized via ATRP Process and Their Membranes for Dye Separation显示文摘To functionalize poly(vinyl chloride)(PVC) for various applications, monomers containing tertiary amine group are incorporated into PVC via atom transfer radical polymerization(ATRP) initiated by the labile chlorines in their backbones. The kinetics of synthesis was carefully investigated, and it is proven that the grafting polymerization process can be effectively controlled by regulating the reaction time. The membranes are fabricated using PVC and copolymers by non-solvent induced phase separation(NIPS) process. The hydrophilicity and pore structure of copolymer membranes were enhanced as well, these membranes are endowed with positive charge. When PDMA%(i.e., the PDMA weight percentage in copolymer) is 31.1%, the flux and Victoria blue B rejection are 26.0 L?m?2?h?1(0.5 MPa) and 91.2%, respectively. Thus, the newly synthesized polymer is proven to be a promising material for dye separation with positive charges. | Li-feng Fang Na-chuan Wang Ming-yong Zhou 朱宝库 Li-ping Zhu Angelin Ebanezar John | 2015 | Chinese Journal of Polymer Science2015，33，11： | 3 |
| 20 | Interactive Image Enhancement by Fuzzy Relaxation显示文摘在这篇论文,一种交互图象改进(IIE ) 技术基于模糊松驰被介绍,它允许用户为改进并且间歇断断续续选择不同紧张层次改进过程根据在应用的其偏爱。基于为图象对比改进的一个模糊松驰算法的集中的分析,首先,这个算法的一个改进版本,被调用 FuzzIIE 方法 1,被在在算法定义的转变导出在集中区域和参数之间的一种关系建议。然后,调用 FuzzIIE 方法 2 的一个方法被使用一个不同模糊松驰函数,在到没有需要介绍重新选择为交互图象改进的参数值。试验性的结果被介绍在不同条件下面表明建议方法的改进能力。关键词交互图象改进 - 模糊松驰 - 模糊集合 - 转线路点 - 集中商明周是有计算智力的中心的一个研究家伙,计算的学校,在英国的德·蒙特福特大学。他的研究兴趣包括模糊逻辑在数据驱动的 neurofuzzy 系统,有模糊计算的内核机器学习( inc 支持向量机器),人工的神经网络和模式识别的系统( type-1 和 type-2 )和应用程序,在无常环境下面的决定支持系统,模型 interpretability 和透明性,聪明的信号并且图象处理。他在这些区域广泛地出版了。John Q。轧收到了 B.Sc。在来自西北的多种工艺的大学的电子工程的度,中国在 1982, M.Eng。在自动控制的度和在来自东南大学的生物医学的电子学的博士学位,中国在 1985 和 1991,分别地。他是在在艾塞克斯大学的计算机科学的一个读者,英国。医生轧了共同创作一本书并且出版了超过 100 篇研究论文。他的研究兴趣包括 neurofuzzy 计算和机器智力,模式识别,信号处理,数据熔化,大脑计算机接口,机器人学,和聪明的系统。徐丽达是在旧统治大学的信息技术的一个教授,美国。他在企业信息系统上担任 IFIP TC8.9 和 IEEE SMC 技术委员会的椅子。他是杂志企业信息系统的成立主编,工业信息科学上的 IEEE 交易 SMC 鈥 ? 部分 C 和 IEEE 交易的伙伴编辑。他也是系统研究和行为的科学的专家系统,和编委成员的地区性的编辑。徐博士是超过 100 篇论文的作者。他的研究兴趣包括企业信息系统,聪明的系统,和决定支持系统。罗伯特·约翰收到了 B.Sc。(爱人) 在从累斯特的数学的度多种工艺,累斯特,英国, M.Sc。在从 UMIST,曼彻斯特,英国,和在 type-2 的博士学位的统计的度模糊逻辑德·蒙特福特大学,累斯特,英国在 1979, 1981,和 2000,分别地。当前,他是一个教授和在德·蒙特福特大学的计算智力的中心的主任。约翰教授是认知神精动力学的国际杂志的编委的一个成员,计算智力的国际杂志,为计算智力和信息和系统科学的国际杂志。他是在 UK 的 EPSRC 学院的 IEEE 神经网络,和一个成员的模糊技术委员会(FTC ) 的一个副主席。他是在在 24 鈥 ?2007 年 7 月 6 日的伦敦的微毛 IEEE 会议的一个合作将军主席。他在模糊逻辑和他的研究兴趣包括的 type-2 的区域广泛地出版了用 type-2 的建模人决策的一般的地模糊逻辑。 | Shang-Ming Zhou John Q.Can Li-Da Xu Robert John | 2007 | International Journal of Automation and computing2007，4，3： | 3 |
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