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| 1 | Effect of contrast-enhanced ultrasound on differential diagnosis of intrahepatic cholangiocarcinoma and arterial phase enhanced hepatic inflammatory lesions显示文摘Objective: To investigate differential diagnosis between intrahepatic cholangiocarcinoma(ICC) and arterial phase enhanced hepatic inflammatory lesions in patients without liver cirrhosis using contrast-enhanced ultrasound(CEUS).Methods: ICC and hepatic inflammatory lesions cases with CEUS and pathological diagnosis between Sep 2013 and Oct 2016 were investigated retrospectively. Imaging features of conventional ultrasound and CEUS were analyzed. The parameters of time intensity curve(TIC), including the arrival time, peak intensity(PI) in the lesions, the starting time for washout, and the intensity difference at 3 min(ΔI_3) after contrast agent infection between the lesion and the liver parenchyma, were compared between ICC and hepatic inflammatory lesions.Results: Twenty-five ICC and fifteen inflammatory patients were included in this study. Seventeen ICC(68.0%)and two inflammatory cases(13.3%) showed bile duct dilatation on conventional ultrasound. Using CEUS, three ICC cases(12.0%) were misdiagnosed as inflammatory lesions and three inflammatory lesions(20.0%) as ICC; two ICC(8.0%) and one inflammatory case(6.7%) could not be made definite diagnosis. Washout started at 34.5±3.5 s and 61.5±12.9 s for ICC and inflammatory lesions respectively(P<0.001). The intensity difference between lesion and liver parenchyma at 3 min after contrast agent injection was 10.8±3.1 dB in ICC and 4.2±2.3 dB in inflammatory group(P<0.001). The sensitivity and specificity differentiating ICC and inflammatory lesions were76% and 87% if the cut-off value of the intensity difference was 7.7 d B.Conclusions: Combined with TIC analysis, and particularly with the characteristic of the early-starting and obvious washout in ICC, CEUS can be useful in differential diagnosis between hepatic inflammatory lesions and ICC. | Shanshan Yin Qiuli Cui Kun Yan Wei Yang Wei Wu Liping Bao Minhua Chen | 2017 | Chinese Journal of Cancer Research2017，29，3： | 13 |
| 2 | Parameter estimation method based on parameter function surface显示文摘By analyzing the structure of the objective function based on error sum of squares and the information provided by the objective function, the essential problems in the current parameter estimation methods are summarized: (1) the information extracted from the objective function based on error sum of squares is unreasonable or even wrong for parameter estimation; and (2) the surface of the objective function based on error sum of squares is more complex than that of the parameter function, which indicates that the optimal parameter values should be searched on the surface of the parameter function instead of the objective function. This paper proposes the concept of sample intersection and demonstrates the uniqueness theorem of intersection point (namely the uniqueness of optimal parameter values). According to the characteristics of parameter function surface and Taylor series expansion, a parameter estimation method based on the sample intersection information extracted from parameter function surface (PFS method) was constructed. The results of theoretical analysis and practical application show that the proposed PFS method can avoid the problems in the current automatic parameter calibration, and has fast convergence rate and good performance in parameter calibration. | BAO WeiMin ZHANG XiaoQin ZHAO LiPing | 2013 | Science China(Technological Sciences)2013，56，6： | 13 |
| 3 | Impact of impregnation pressure on desulfurization performance of Zn-based sorbents supported on semi-coke显示文摘High-pressure impregnation, a new preparation method for sorbents to remove H2S from hot coal gas, is introduced in this paper. Semi-coke (SC) and ZnO is selected as the support and active component of sorbent, respectively. The sorbent preparation process includes high-pressure impregnation, filtration, ovendry and calcination. The aim of this research is to primarily study the effects of the impregnation pressure on physical properties and desulfurization ability of the sorbent. The desulfurization experiment was carried out in a fixed-bed reactor at 500°C and a simulated coal gas used in this work was composed of CO (33 vol%), H2 (39 vol%), H2S (300 ppm in volume), and N2 (balance). Experimental results show that the pore structure of the SC support can be improved effectively and ZnO active component can be uniformly dispersed on the support, with the small particle size of 10-500 nm. Sorbents prepared using high-pressure impregnation have better desulfurization capacity and their active components have higher utilization rate. P20-ZnSC sorbent, obtained by high-pressure impregnation at 20 atm, has the best desulfurization ability with a sulfur capacity of 7.54 g S/100g sorbent and a breakthrough time of 44 h. Its desulfurization precision and efficiency of removing H2S from the middle temperature gases can reach <1 ppm and >99.7%, respectively, before sorbent breakthrough. | Xianrong Zheng Weiren Bao Qingmai Jin Ruiyuan He Liping Chang Kechang Xie | 2012 | Journal of Natural Gas Chemistry2012，21，1： | 10 |
| 4 | A semi-physical sediment yield model for estimation of suspended sediment in loess region显示文摘Sediment yield is a complex function of many environmental factors including climate,hydrology,vegetation,basin topography,soil types,and land cover.We present a new semi-physical watershed sediment yield model for the estimation of suspended sediment in loess region.This model is composed by three modules in slope,gully,and stream phases.For slope sediment yield,a balance equation is established based on the concept of hydraulic erosion capacity and soil erosion resistance capacity.According to the statistical analysis of watershed characteristics,we use an exponential curve to approximately describe the spatial variability of watershed soil erosion resistance capacity.In gully phase,the relationship between gully sediment concentration and flow velocity is established based on the Bagnold' stream power function.In the stream phase,we assume a linear dependence of the sediment volume in the reach on the weighted sediment input and output.The proposed sediment yield model is operated in conjunction with a conceptual hydrologic model,and is tested over 16 regions including testing grounds,and small,medium and large watersheds in the loess plateau region in the mid-reach of Yellow River.Our results indicate that the model is reasonable in structure and is able to provide a good simulation of sediment generation and transportation processes at both flood event scale and inter-annual time scale.The proposed model is generally applicable to the watersheds with soil texture similar to that of the loess plateau region in the Yellow River basin in China. | Wei Si Weimin Bao Peng Jiang Liping Zhao Simin Qu | 2017 | International Journal of Sediment Research2017，32，1： | 7 |
| 5 | Desulfurization kinetics of ZnO sorbent loaded on semi-coke support for hot coal gas显示文摘Zn-based sorbent (Z20SC) prepared through semi-coke support in 20 wt% zinc nitrate solution by high-pressure impregnation presents an excellent desulfurization capacity in hot coal gas,in which H2 S can not be nearly detected in the outlet gas before 20 h breakthrough time.The effects of the main operational conditions and the particle size of Z20SC sorbent on its desulfurization performances sorbent were investigated in a fixed-bed reactor and the desulfurization kinetics of Z20SC sorbent removing H2 S from hot coal gas was calculated based on experimental data.Results showed that the conversion of Z20SC sorbent desulfurization reaction increased with the decrease of the particle size of the sorbent and the increases of gas volumetric flow rate,reaction temperature and H 2 S content in inlet gas.Z20SC sorbent obtained from hydrothermal synthesis by high-pressure impregnation possessed much larger surface area and pore volume than semi-coke support,and they were significantly reduced after the desulfurization reaction.The equivalent grain model was reasonably used to analyze experimental data,in which k s=4.382×10-3 exp(-8.270×103/RgT) and Dep=1.262×10-4exp(1.522×104/RgT).It suggests that the desulfurization reaction of the Z20SC sorbent is mainly controlled by the chemical reaction in the initial stage and later by the diffusion through the reacted sorbent layer. | Zhiwei Ma Xianrong Zheng Liping Chang Ruiyuan He Weiren Bao | 2012 | Journal of Natural Gas Chemistry2012，21，5： | 7 |
| 6 | A review of recent researches on Bunsen reaction for hydrogen production via S–I water and H2S splitting cycles显示文摘The Bunsen reaction is the center reaction for both the sulfur–iodine water splitting cycle for hydrogen production and the novel hydrogen sulfide splitting cycle for hydrogen and sulfuric acid production from the sulfur-containing gases.This paper reviews the research progress of the Bunsen reaction in recent 10–15 years.Researches were initially focused on the optimization of the operating conditions of the conventional Bunsen reaction requiring excessive water and iodine to improve the products separation efficiency and to avoid the side reactions and iodine vapor deposition.Alternative methods including electrochemical methods,precipitation methods,and non-aqueous solvent methods had their respective advantages,but still faced challenges.In development of the technology of H2S splitting cycle,dissolving iodine in toluene solvent could render the Bunsen reaction to occur with the flowable I2 stream at ambient temperature such that the side reactions and iodine vaporization can be avoided and the corrosion hazard lessened.It also prevented the Bunsen reaction from using excessive iodine and water.The products from the Bunsen reaction including HI,H2SO4,H2O,and toluene could be directly electrolyzed. | Ke Zhang Weiren Bao Liping Chang Hui Wangg | 2019 | Journal of Energy Chemistry2019，28，6： | 7 |
| 7 | Speciation and thermal transformation of sulfur forms in high-sulfur coal and its utilization in coal-blending coking process:A review显示文摘The utilization of high-sulfur coal is becoming more urgent due to the excessive utilization of low-sulfur,high-quality coal resources,and sulfur removal from high-sulfur coal is the most important issue.This paper reviews the speciation,forms and distribution of sulfur in coal,the sulfur removal from raw coal,the thermal transformation of sulfur during coal pyrolysis,and the sulfur regulation during coal-blending coking of high organic-sulfur coals.It was suggested that the proper characterization of sulfur in coal cannot be obtained only by either chemical method or instrumental characterization,which raises the need of a combination of current or newly adopted characterization methods.Different from the removal of inorganic sulfur from coal,the organic sulfur can only be partly removed by chemical technologies;and the coal structure and property,particularly high-sulfur coking coals which have caking ability,may be altered and affected by the pretreatment processes.Based on the interactions among the sulfur radicals,sulfur-containing and hydrogen-containing fragments during coal pyrolysis and the reactions with minerals or nascent char,regulating the sulfur transformation behavior in the process of thermal conversion is the most effective way to utilize high organic-sulfur coals in the coke-making industry.An in-situ regulation approach of sulfur transformation during coal-blending coking has been suggested.That is,the high volatile coals with an appropriate releasing temperature range of CH4 overlapping well with that of H2 S from high organic-sulfur coals is blended with high organic-sulfur coals,and the C–S/C–C bonds in some sulfur forms are catalytically broken and immediately hydrogenated by the hydrogencontaining radicals generated from high volatile coals.Wherein,the effect of mass transfer on sulfur regulation during the coking process should be considered for the larger-scale coking tests through optimizing the ratios of different coals in the coal blend. | Yanfeng Shen Yongfeng Hu Meijun Wang Weiren Bao Liping Chang Kechang Xie | 2021 | Chinese Journal of Chemical Engineering2021，34，7： | 5 |
| 8 | Single-cell transcriptomic analysis of somatosensory neurons uncovers temporal development of neuropathic pain显示文摘Peripheral nerve injury could lead to chronic neuropathic pain.Understanding transcriptional changes induced by nerve injury could provide fundamental insights into the complex pathogenesis of neuropathic pain.Gene expression profiles of dorsal root ganglia(DRG)in neuropathic pain condition have been studied.However,little is known about transcriptomic changes in individual DRG neurons after peripheral nerve injury. | Kaikai Wang Sashuang Wang Yan Chen Dan Wu Xinyu Hu Yingjin Lu Liping Wang Lan Bao Changlin Li Xu Zhang | 2021 | Cell Research2021，31，8： | 5 |
| 9 | High-Q microresonators on 4H-silicon-carbide-on-insulator platform for nonlinear photonics显示文摘The realization of high-quality(Q)resonators regardless of the underpinning material platforms has been a ceaseless pursuit,because the high-Q resonators provide an extreme environment for confining light to enable observations of many nonlinear optical phenomenon with high efficiencies.Here,photonic microresonators with a mean Q factor of 6.75×10^(6)were demonstrated on a 4H-silicon-carbide-on-insulator(4H-SiCOI)platform,as determined by a statistical analysis of tens of resonances.Using these devices,broadband frequency conversions,including second-,third-,and fourth-harmonic generations have been observed.Cascaded Raman lasing has also been demonstrated in our SiC microresonator for the first time,to the best of our knowledge.Meanwhile,by engineering the dispersion properties of the SiC microresonator,we have achieved broadband Kerr frequency combs covering from 1300 to 1700nm.Our demonstration represents a significant milestone in the development of SiC photonic integrated devices. | Chengli Wang Zhiwei Fang Ailun Yi Bingcheng Yang Zhe Wang Liping Zhou Chen Shen Yifan Zhu Yuan Zhou Rui Bao Zhongxu Li Yang Chen Kai Huang Jiaxiang Zhang Ya Cheng Xin Ou | 2021 | Light(Science & Applications)2021，10，8： | 4 |
| 10 | Preparation of dye-sensitized solar cells with high photocurrent and photovoltage by using mesoporous titanium dioxide particles as photoanode material显示文摘几 mesoporous TiO 2(MT ) 材料在跟随 poly 使用的一个热水的过程(乙烯乙二醇) 的不同条件下面被综合 -block-poly(propylene-glycol)-block-poly(ethylene-glycol)(P123 ) 作为是的模板和钛 isopropoxide 钛来源。Ti/P123 的臼齿的比率,和在一个压热器的反应解决方案的 pH 值被调查。象 BrunauerEmmettTeller (赌注) 那样的各种各样的技术, X 光检查衍射(XRD ) , X 光检查光电子光谱学(XPS ) ,激光拉曼 spectrometry (LRS ) ,扫描电子显微镜学(SEM ) ,和高分辨率的传播电子显微镜学(HRTEM ) 被用来描绘产品。然后,这些材料被装配进敏化染料的太阳能电池(DSSC ) 。JV 曲线和电气化学的阻抗光谱学(EIS ) 的分析被使用描绘房间。结果显示特定的表面区域和这些材料的水晶的结构为房间提供高光电流的可能性,并且标本的结构的特征导致了,这增加了房间的电子转移抵抗,它为 DSSC 的 photovoltage 的改进是有益的。包含 MT 材料的房间的最高光电的变换效率到达了 8.33% ,与基于 P25 的太阳能电池(5.88%) 的相比,它增加了 41.7% 。 | Yi Zhang Bao Zhang Xiao Peng Lin Liu Shuo Dong Liping Lin Si Chen Shuxian Meng Yaqing Feng | 2015 | Nano Research2015，8，12： | 4 |
| 11 | Effect of impregnation methods on sorbents made from lignite for desulfurization at middle temperature显示文摘With lignite after vacuum drying as the raw material,a series of Zn-based sorbents were prepared by static impregnation,ultrasonic-assisted impregnation,bubbling-assisted impregnation and high-pressure impregnation.The physical properties and the desulfurization performances of Zn-based sorbents were studied systematically by XRD,BET,AAS characterization techniques and the fixed-bed desulfurization evaluation apparatus.The sorbents obtained by high-pressure impregnation method have a larger specific surface area,pore volume and pore diameter comparing with other methods,which is conducive to the sulfidation reaction of hydrogen sulfide gas in the sorbent.The effects of pressure during the high-pressure impregnation and concentration of Zn(NO3)2 precursor solution on the sorbents properties and desulfurization behavior were investigated.The higher the impregnation pressure and the concentration of impregnation solution are,the greater the amount of the active components are uploaded.However,overhigh impregnation pressure can cause collapse and blocking of the carrier pore.The optimal operating condition of high-pressure impregnation method for preparing the sorbents was the impregnation pressure of 20 atm and the solution concentration of 41%.Under that condition,the sorbent had the best desulfurization ability with a sulfur capacity of 13.94 gS/100 gsorbent and a breakthrough time of 54 h.Its desulfurization precision and efficiency of removing H2S before sorbent breakthrough from the middle temperature gases of 400℃ can reach<5 ppm and>99%,respectively.Sorbents could be regenerated under the condition of 1 vol%O2,20 vol% H2O,0.5 vol% NH3,and N2balance gas.The regenerated sorbent could be used for repeated absorption of H2S with a slight decrease in desulfurization effect. | Yurong Dong Xiurong Ren Meijun Wang Qiang He Liping Chang Weiren Bao | 2013 | Journal of Energy Chemistry2013，22，5： | 3 |
| 12 | Effect of pulsatile perfusion during cardiopulmonary bypass in terms of radial artery sphygmogram显示文摘OBJECTIVE: To investigate a quantitative method for using radial artery pulse waveforms to assess the effect of pulsatile flow during cardiopulmonary bypass(CPB).METHODS: A total of 34 adults with heart disease who underwent open-heart surgery between April2010 and January 2011 were randomized into a pulsatile perfusion group(n=17) and a non-pulsatile perfusion group(n=17). Radial arterial pulse waveforms of pulsatile and non-pulsatile perfusion patients were observed and compared before and during CPB.RESULTS: No pulse waveform could be detected at patients' radial artery in both groups when the aorta was cross-clamped. Pulse waveforms could be detected at pulsatile perfusion patients' radial artery, but could not be detected at non-pulsatile perfusion patients' radial artery during CPB. Additionally, patients' pulse waveforms during pulsatile perfusion were lower than those before the operation.CONCLUSION: Our findings indicate that radial artery sphygmogram can be used as a valid indicator to evaluate the effectiveness of pulsatile perfusion during CPB. | Zhifeng Zhang Jiatuo Xu Enyuan Zhu Qi Zhang Lu Yu Yongbing Qiu Jianguo Tang Zhaofu Fei Xin Li Liping Tu Chouping Han Ying Liu Zhen Guo Changle Zhou Meiyu Shi Yingxin Qian Yimin Bao Xinming Ji | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 2 |
| 13 | Pulmonary Angiogenesis in a Rat Model of Hepatopulmonary Syndrome显示文摘 | Junlan Zhang Bao Luo Liping Tang Yongming Wang Cecil R. Stockard Inga Kadish Thomas Van Groen William E. Grizzle Selvarangan Ponnazhagan Michael B. Fallon | 2009 | Gastroenterology2009，，3： | 2 |
| 14 | Potato starch as a highly enantioselective system for temperature - dependent electrochemical recognition of tryptophan isomers 显示文摘 | Liping Bao Yongxin Tao Xiaogang Gu | 2016 | Electrochemistry Communications2016，，64： | 1 |
| 15 | Parameter esti- mation method based on parameter function surface显示文摘 | BAO WeiMin ZHANG XiaoQin ZHAO LiPing | | Science0，，： | 1 |
| 16 | Prediction of doxorubicin sensitivity in gastric cancers based on aset of novel markers显示文摘 | Hao Liu Nanlin Li Liping Yao Lei Jiang Guoqiang Bao Jipeng Li Qingjiu Ma Zhiguo Liu | 2008 | Oncology Reports2008，，4： | 1 |
| 17 | Study on main factors influencing acetylene formation during coal pyrolysis in arc plasma 显示文摘 | Bao Weiren Chang Liping Lu Yongkang | 2006 | Process Safety and Environmental Protection2006，84，3： | 1 |
| 18 | Decoding effects of psychoactive drugs in a high-dimensional space of eye movements in monkeys显示文摘Oculomotor behavior has been shown to be correlated with mental disorders in clinics,making it promising for disease diagnosis.Here we developed a thorough oculomotor test toolkit,involving saccade,smooth pursuit,and fixation,allowing the examination of multiple oculomotor parameters in monkey models induced by psychoactive drugs.Eye movements were recorded after daily injections of phencyclidine(PCP)(3.0 mg/kg),ketamine(0.8 mg/kg)or controlled saline in two macaque monkeys.Both drugs led to robust reduction in accuracy and increment in reaction time during high cognitive-demanding tasks.Saccades,smooth pursuit,and fixation stability were also significantly impaired.During fixation,the involuntary microsaccades exhibited increased amplitudes and were biased toward the lower visual field.Pupillary response was reduced during cognitive tasks.Both drugs also increased sensitivity to auditory cues as reflected in auditory evoked potentials(AEPs).Thus,our animal model induced by psychoactive drugs produced largely similar abnormalities to that in patients with schizophrenia.Importantly,a classifier based on dimension reduction and machine learning could reliably identify altered states induced by different drugs(PCP,ketamine and saline,accuracy=93%).The high performance of the classifier was reserved even when data from one monkey were used for training and testing the other subject(averaged classification accuracy=90%).Thus,despite heterogeneity in baseline oculomotor behavior between the two monkeys,our model allows data transferability across individuals,which could be beneficial for future evaluation of pharmaceutical or physical therapy validity. | Xu Liu Zhixian Cheng He Lin Jiangxiu Tan Wenyao Chen Yichuan Bao Ying Liu Lei Zhong Yitian Yao Liping Wang Jijun Wang Yong Gu | 2023 | National Science Review2023，10，11： | 1 |
| 19 | Parameter esti- mation method based on parameter function surface 显示文摘 | BAO WeiMin ZHANG XiaoQin ZHAO LiPing | | Techno- logical Sciences0，，： | 1 |
| 20 | In situ synthesis of CuSAPO-34/cordierite and its selective catalytic reduction of nitrogen oxides in vehicle exhaust: The effect of HF显示文摘 | Jiancheng Wang Zhiqiang Liu Gang Feng Liping Chang Weiren Bao | 2012 | Fuel2012，，： | 1 |
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