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| 1 | The development of China's Yangtze River Economic Belt:how to make it in a green way?显示文摘The Yangtze River is one of the largest and longest rivers in Asia.The river originates in the Tibet-Qinghai Plateau(headwater reach),passes through the mountainous provinces of Sichuan,Yunnan and Chongqing(upper reach),flows into the Central Plain(middle reach)and Lower Plain(lower reach),and finally empties into the East China Sea in Shanghai(estuary).The Yangtze River Economic Belt(YREB;Fig.1)has a surface area of 2.1 | Yushun Chen Shuanghu Zhang Desheng Huang Bai-Lian Li Junguo Liu Wenjin Liu Jing Ma Fang Wang Yong Wang Shengjun Wu Yegang Wu Jinyue Yan Chuanbo Guo Wei Xin Hao Wang | 2017 | Science Bulletin2017，62，9： | 20 |
| 2 | Effect of Sc addition on microstructure and mechanical properties of 1460 alloy显示文摘The effect of minor addition of Sc on microstructure,age hardening behavior,tensile properties and fracture morphology of 1460 alloy have been studied. It is found that Sc content increase from 0.11 wt% to 0.22 wt% is favorable for grain refinement in as-cast alloy but results in a coarsening of Cu-rich particles. The alloy with 0.11 wt% Sc exhibits enhanced mechanical properties and age hardening effect. Transmission electron microscopy(TEM) investigations on the alloy with 0.11 wt% Sc have suggested that a large amount of Al3(Sc,Zr) particles precipitated at the earlier aging may inhibit recrystallization effectively. | Juan Ma Desheng Yan Lijian Rong Yiyi Li | 2014 | Progress in Natural Science:Materials International2014，24，1： | 10 |
| 3 | Arsenic(V)removal from groundwater by GE-HL nanofiltration membrane:effects of arsenic concentration,pH,and co-existing ions显示文摘A laboratory-scale investigation was performed to study arsenic(As(V))removal by negatively charged GE-HL nanofiltration(NF)membrane in simulated drinking water.Effects of As(V)concentration(0–200μg·L–1),pH,and co-ions and counter-ions were investigated.The NF membrane presented good stability,and the rejection rates exceeded 90%.The rejection rates of As(V)decreased with the increase of As(V)concentration,while it increased with the increase of pH(reached 96%at pH 6.75).Moreover,a negative relationship was observed between the co-existing ions of Cl^(–),Na^(+),SO_(4)^(2–),and Ca^(2+)and the removal of As(V),in which bivalent ions presented more significant effects than monovalent ions. | Xiaowei WANG Wenjun LIU Desheng LI Weifang MA | 2009 | Frontiers of Environmental Science & Engineering2009，3，4： | 5 |
| 4 | Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2显示文摘Receptor recognition and subsequent membrane fusion are essential for the establishment of successful infection by SARS-CoV-2.Halting these steps can cure COVID-19.Here we have identified and characterized a potent human monoclonal antibody,HB27,that blocks SARS-CoV-2 attachment to its cellular receptor at sub-nM concentrations.Remarkably,HB27 can also prevent SARS-CoV-2 membrane fusion.Consequently,a single dose of HB27 conferred effective protection against SARS-CoV-2 in two established mouse models.Rhesus macaques showed no obvious adverse events when administrated with10 times the effective dose of HB27.Cryo-EM studies on complex of SARS-CoV-2 trimeric S with HB27 Fab reveal that three Fab fragments work synergistically to occlude SARS-CoV-2 from binding to the ACE2 receptor.Binding of the antibody also restrains any further conformational changes of the receptor binding domain,possibly interfering with progression from the prefusion to the postfusion stage.These results suggest that HB27 is a promising candidate for immuno-therapies against COVID-19. | Ling Zhu Yong-Qiang Deng Rong-Rong Zhang Zhen Cui Chun-Yun Sun Chang-Fa Fan Xiaorui Xing Weijin Huang Qi Chen Na-Na Zhang Qing Ye Tian-Shu Cao Nan Wang Lei Wang Lei Cao Huiyu Wang Desheng Kong Juan Ma Chunxia Luo Yanjing Zhang Jianhui Nie Yao Sun Zhe Lv Neil Shaw Qianqian Li Xiao-Feng Li Junjie Hu Liangzhi Xie Zihe Rao Youchun Wang Xiangxi Wang Cheng-Feng Qin | 2021 | National Science Review2021，8，3： | 3 |
| 5 | Spectroscopic Analysis on the Effect of Temperature on Kunitz Domain 1 of Human Tissue Factor Pathway Inhibitor-2显示文摘Kunitz 领域 1 人的织物因素 pathwayinhibitor-2 (hTFPI-2/KD1 ) 的符合构造被 Fourier 变换学习了红外线的光谱学,圆形的二色性,和拉曼光谱学。hTFPI-2/KD1 在详细 conformational 揭示的 Fouriertransform 红外线的光谱学,圆形的二色性和拉曼光谱学观察的激烈的蛋白质改变的 25 ° C .The 包含了近似 17%alpha-helices,24% 贝它海滨, 46% 随机的卷, 13% 贝它拐弯,和二种二硫键(gggand tgt ) ,这被发现那 hTFPI-2/KDlwas 热地稳定。然而, KD1 能在高温度形成一种中间的形式,当温度被降低时,然后回到它的正常符合构造。活动试金也证明 thathTFPI-2/KDl 能在为 5min 被加热到 80 ° C 以后在胞质素上保留它的禁止的活动。 | Chenqi ZHANG Desheng KONG Xingang LIU Xiaomin YAN Linsen DAI Duan MA | 2007 | Acta Biochimica et Biophysica Sinica2007，39，6： | 3 |
| 6 | Observation and optimization of 2 μm mode‐locked pulses in all‐fiber net anomalous dispersion laser cavity显示文摘We integrally demonstrate 2μm mode-locked pulses performances in all-fiber net anomalous dispersion cavity.Stable mode-locking operations with the center wavelength around 1950–1980 nm can be achieved by using the nonlinear polarization rotation structure and properly designing the dispersion management component.Conventional soliton is firstly obtained with a total anomalous dispersion cavity.Due to the contribution of commercial ultra-high numerical aperture fibers,net dispersion is reduced to-0.077 ps2.So that stretched pulse with 19.4 nm optical bandwidth is obtained and the de-chirped pulse-width can reach 312 fs using extra-cavity compression.Under pump power greater than 890 mW,stretched pulse can evolve into noise-like pulse with 41.3 nm bandwidth.The envelope and peak of such broadband pulse can be compressed with up to 2.2 ps and 145 fs,respectively.The single pulse energy of largely chirped stretched and noise-like pulse can reach 1.785 nJ and 1.53 nJ,respectively.Furthermore,extra-cavity compression can also contribute to a significant increase of peak power. | Wanzhuo Ma Desheng Zhao Runmin Liu Tianshu Wang Quan Yuan Hao Xiong Haiying Ji Huilin Jiang | 2020 | Opto-Electronic Advances2020，3，11： | 2 |
| 7 | Oil production rate predictions for steam assisted gravity drainage based on high-pressure experiments显示文摘Dual-well steam assisted gravity drainage(SAGD) has significant potential for extra-heavy oil recovery.China is conducting two dual-well SAGD pilot projects in the Fengcheng extra-heavy oil reservoir.Quick,direct predictions of the oil production rate by algebraic models rather than complex numerical models are of great importance for designing and adjusting the SAGD operations.A low-pressure scaled physical simulation was previously used to develop two separate theoretical models corresponding to the two different growth stages observed in the SAGD steam chambers,which are the steam chamber rising stage and the steam chamber spreading stage.A high-pressure scaled model experiment is presented here for one dual-well SAGD pattern to further improve the prediction models to reasonably predict oil production rates for full production.Parameters that significantly affect the oil recovery during SAGD were scaled for the model size based on the reservoir characteristics of the Fengcheng reservoir in China.Experimental results show the relationship between the evolution of the steam chamber and the oil production rate during the entire production stage.High-pressure scaled model test was used to improve the gravity drainage models by modifying empirical factors for the rising model and the depletion model.A new division of the SAGD production regime was developed based on the relationship between the oil production rate and the evolution of steam chamber.A method was developed to couple the rising and depletion models to predict oil production rates during the SAGD production,especially during the transition period.The method was validated with experiment data and field data from the literature.The model was then used to predict the oil production rate in the Fengcheng reservoir in China and the Athabasca reservoir in Canada. | GUO Jia ZAN Cheng MA DeSheng SHI Lin | 2013 | Science China(Technological Sciences)2013，56，2： | 2 |
| 8 | Progress and prospects of carbon dioxide capture,EOR-utilization and storage industrialization显示文摘Carbon dioxide capture,EOR-utilization and storage(CCUS-EOR)are the most practical and feasible large-scale carbon reduction technologies,and also the key technologies to greatly improve the recovery of low-permeability oil fields.This paper sorts out the main course of CCUS-EOR technological development abroad and its industrialization progress.The progress of CCUS-EOR technological research and field tests in China are summarized,the development status,problems and challenges of the entire industry chain of CO_(2) capture,transportation,oil displacement,and storage are analyzed.The results show a huge potential of the large-scale application of CCUS-EOR in China in terms of carbon emission reduction and oil production increase.At present,CCUS-EOR in China is in a critical stage of development,from field pilot tests to industrialization.Aiming at the feature of continental sedimentary oil and gas reservoirs in China,and giving full play to the advantages of the abundant reserves for CO_(2) flooding,huge underground storage space,surface infrastructure,and wide distribution of wellbore injection channels,by cooperating with carbon emission enterprises,critical technological research and demonstration project construction should be accelerated,including the capture of low-concentration CO_(2) at low-cost and on large-scale,supercritical CO_(2) long-distance transportation,greatly enhancing oil recovery and storage rate,and CO_(2) large-scale and safe storage.CCUS-EOR theoretical and technical standard system should be constructed for the whole industrial chain to support and promote the industrial scale application,leading the rapid and profitable development of CCUS-EOR emerging industrial chain with innovation. | YUAN Shiyi MA Desheng LI Junshi ZHOU Tiyao JI Zemin HAN Haishui | 2022 | Petroleum Exploration and Development2022，49，4： | 2 |
| 9 | Expression and characterization of the first kunitz domain of human tissue factor pathway inhibitor-2显示文摘 | Desheng Kong Duan Ma Hao Bai Hongshen Guo Xu Cai Wei Mo Qiqun Tang Houyan Song | 2004 | Biochemical and Biophysical Research Communications2004，，4： | 1 |
| 10 | Design and Performance of a Water-cooled Permanent Magnet Retarder for Heavy Vehicles显示文摘 | Lezhi Ye Desheng Li Yuanjing Ma Bingfeng Jiao | 2011 | IEEE Transactions on Energy Conversion2011，26，3： | 1 |
| 11 | Statistical Verification of Hydraulic Units in a Heterogeneous Reservoir of the Liaohe Oilfield显示文摘The Liaohe Oil Field has passed peak production and correct discrimination of hydraulic units(HU) has vital significance for forecasting remaining oil distribution in a petroleum reservoir, enhancing the recovery ratio and adjusting development plans. A unified multi-parameter cluster analysis and fuzzy quality synthetic evaluations have been used for the identification of reservoir hydraulic units. This paper analyzes three predictions within Block Shen-95: intersection of multiple well-logs, independent mulitple well-logs and mutually exclusive multiple well-logs. HU has been delineated to conveniently compute permeability and serve as the basis of a structural model for enhanced simulation study. HU has been defined by the flow zone indicator concept using a modified Kozeny-Carmen equation. The Bayesian method was used to predict HU at uncored wells by constructing a probability database and then integrating established HU and well-log responses at cored wells. HU has then been inferred from the database using well-log responses. Estimated permeability from predicted HU gave an overall improved permeability match when compared with traditional statistical methods. The method proved most favourable when using mutually exclusive multiple well-logs, most significant by integrating reservoir performance with HU distribution and indicating that reasonable prediction had been obtained at uncored wells using this mutually exclusive approach. The distribution pattern was revealed by interwell HU correlation using modified depositional cycles as a framework, an integration step that qualitatively examines prediction accuracy. Detailed analysis has been carried out to determine and verify the characteristics of each kind of flow unit, providing a detailed geological basis for control of the oil field. | Wei Zhou Shuxian Liang Desheng Ma Zhonghua Tang | 2014 | Journal of Earth Science2014，25，6： | 1 |
| 12 | Local mild hypothermia with thrombolysis for acute ischemic stroke within a 6-h window显示文摘 | Min Bi Qilin Ma Shiyang Zhang Jianpeng Li Yidan Zhang Longting Lin Suijun Tong Desheng Wang | 2011 | Clinical Neurology and Neurosurgery2011，，： | 1 |
| 13 | A power and thermal management system for long endurance hypersonic vehicle显示文摘Due to the pneumatic heating and combustion effect,the scramjet engine of hypersonic vehicle faces high temperature challenge.It is necessary to comprehensively consider its thermal management and power generation together.A new Power and Thermal Management System(PTMS)combined with Supercritical Carbon Dioxide(SCO_(2))closed Brayton cycle and fuel vapor turbine is proposed and discussed in this paper.The new PTMS can meet the cooling requirement of hypersonic vehicle at Mach number 6–7,and avoid the coking and scrapping in the scramjet cooling channels.Compared with the PTMS only based on fuel vapor turbine,the new PTMS utilizes the waste heat of scramjet to generate more electricity.In addition,it can reduce the use of fuel sink for cooling,and the additional weight penalty can be compensated for long endurance hypersonic flight. | Liang GUO Liping PANG Xiaodong YANG Jingquan ZHAO Desheng MA | 2023 | Chinese Journal of Aeronautics2023，36，2： | 1 |
| 14 | hiPSC-derived NSCs effectively promote the functional recovery of acute spinal cord injury in mice显示文摘Spinal cord injury(SCI)is a common disease that results in motor and sensory disorders and even lifelong paralysis..The transplantation of stem cells,such as embryonic stem cells(ESCs),induced pluripotent stem cells(iPSCs),mesenchymal stem cells(MSCs),or subsequently generated stem/progenitor cells,was predicted to be a promising treatment for SCI.In this study,we aimed to investigate effect of human iPSC-derived neural stem cells(hiPSC-NSCs)and umbilical cord-derived MSCs(huMSCs)in a mouse model of acute SCI.Acute SCI mice model was established and were randomly treated as phosphate-buffered saline(PBS)(control group),repaired with 1×10^(5)hiPSC-NSCs(NSC group),and 1×10^(5)huMSCs(MSC group),respectively,in a total of 54 mice.Hind limb motor function was evaluated in open-field tests using the Basso Mouse Scale(BMS)at days post operation(dpo)1,3,5,and 7 after spinal cord injury,and weekly thereafter.Spinal cord and serum samples were harvested at dpo 7,14,and 21. | Ma Jun Kong Desheng Cui Huixian | 2021 | 解剖学杂志2021，44，S01： | 1 |
| 15 | Analysis of the time domain characteristics of tapered semiconductor lasers显示文摘We use traveling wave coupling theory to investigate the time domain characteristics of tapered semiconductor lasers with DBR gratings.We analyze the influence of the length of second order gratings on the power and spectrum of output light,and optimizing the length of gratings,in order to reduce the mode competition effect in the device,and obtain the high power output light wave with good longitudinal mode characteristics. | Desheng Zeng Li Zhong Suping Liu Xiaoyu Ma | 2020 | Journal of Semiconductors2020，41，3： | 1 |
| 16 | Study on SAGD technology for ultra heavy oil in dual horizontal wells 显示文摘 | XI Changfeng MA Desheng LI Xiuluan | 2010 | Journal of Southwest Petroleum University (Science & Technology Edition)2010，32，4： | 1 |
| 17 | Novel methanol-tolerant Ir-S/C chalcogenide electrocatalysts for oxygen reduction in DMFC fuel cell显示文摘Novel methanol-tolerant oxygen-reduction catalysts,iridium-sulphur (Ir-S) chalcogenides with different Ir/S atomic ratios,were synthesized via a precipitation method using H 2 IrCl 6 and Na 2 SO 3 as the Ir and S precursors.Powder X-ray diffraction (XRD) and transmission electron microscopy (TEM) were used to characterize the Ir x S 1 x/C chalcogenide catalysts.Particle size ranging from 2.5 to 2.8 nm though obvious agglomeration was found on carbon support.However,these chalcogenide catalysts showed strong catalytic activity towards the oxygen reduction reaction (ORR) and high methanol tolerance,strongly suggesting these novel catalysts as promising candidates for direct methanol fuel cell (DMFC) cathode applications. | Jingyu Ma Desheng Ai Xiaofeng Xie Jianwei Guo | 2011 | Particuology2011，9，2： | 1 |
| 18 | Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene显示文摘 | Haiqing Ma Desheng Weng Yibing Chen | 2010 | Mol Cancer2010，9，： | 1 |
| 19 | A spike-trimer protein-based tetravalent COVID-19 vaccine elicits enhanced breadth of neutralization against SARS-CoV-2 Omicron subvariants and other variants显示文摘Multivalent vaccines combining crucial mutations from phylogenetically divergent variants could be an effective approach to defend against existing and future SARS-Co V-2 variants.In this study,we developed a tetravalent COVID-19 vaccine SCTV01E,based on the trimeric Spike protein of SARS-Co V-2 variants Alpha,Beta,Delta,and Omicron BA.1,with a squalenebased oil-in-water adjuvant SCT-VA02B.In the immunogenicity studies in na?ve BALB/c and C57BL/6J mice,SCTV01E exhibited the most favorable immunogenic characteristics to induce balanced and broad-spectrum neutralizing potencies against pre-Omicron variants(D614G,Alpha,Beta,and Delta)and newly emerging Omicron subvariants(BA.1,BA.1.1,BA.2,BA.3,and BA.4/5).Booster studies in C57BL/6J mice previously immunized with D614G monovalent vaccine demonstrated superior neutralizing capacities of SCTV01E against Omicron subvariants,compared with the D614G booster regimen.Furthermore,SCTV01E vaccination elicited na?ve and central memory T cell responses to SARS-Co V-2 ancestral strain and Omicron spike peptides.Together,our comprehensive immunogenicity evaluation results indicate that SCTV01E could become an important COVID-19 vaccine platform to combat surging infections caused by the highly immune evasive BA.4/5 variants.SCTV01E is currently being studied in a head-to-head immunogenicity comparison phase 3 clinical study with inactivated and m RNA vaccines(NCT05323461). | Rui Wang Hongpeng Huang Chulin Yu Chunyun Sun Juan Ma Desheng Kong Yalong Lin Dandan Zhao Shaozheng Zhou Jianbo Lu Sai Cao Yanjing Zhang Chunxia Luo Xuefeng Li Yang Wang Liangzhi Xie | 2023 | Science China(Life Sciences)2023，66，8： | 1 |
| 20 | Skin-inspired electronics:emerging semiconductor devices and systems显示文摘Current electronics are driven by advanced microfabrication for fast and efficient information processing.In spite of high performance,these wafer-based devices are rigid,non-degradable,and unable to autonomous repair.Skin-inspired electronics have emerged as a new class of devices and systems for next-generation flexible and wearable electronics.The technology gains inspiration from the structures,properties,and sensing mechanisms of the skin,which may find a broad range of applications in cutting-edge fields such as healthcare monitoring,human-machine interface,and soft robotics/prostheses.Practical demands have fueled the development of electronic materials with skin-like properties in terms of stretchability,self-healing capability,and biodegradability.These materials provide the basis for functional sensors with innovative and biomimetic designs.Further system-level integrations and optimizations enable new forms of electronics for real-world applications.This review summarizes recent advancements in this active area and speculates on future directions. | Zhong Ma Desheng Kong Lijia Pan Zhenan Bao | 2020 | Journal of Semiconductors2020，41，4： | 1 |
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