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| 1 | Relationship of Helicobacterpylori eradication with gastric cancer and gastric mucosal histological changes: a 10-year follow-up study显示文摘 | Zhou Liya Lin Sanren Ding Shigang Huang Xuebiao Jin Zhu Cui Rongli Meng Lingmei Li Yuan Zhang Li Guo Changji Xue Yan Yan Xiu'e Zhang Jing | 2014 | Chinese Medical Journal2014，，8： | 28 |
| 2 | Hypertensive stretch regulates endothelial exocytosis of WeibeI-Palade bodies through VEGF receptor 2 signaling pathways显示文摘Weibel-Palade 身体(WPB ) 的调整 endothelial exocytosis,在白血球 trafficking 的第一个阶段,在发炎和损害起一个枢轴的作用。尖锐的机械段仔细与脉管的发炎被联系了,尽管精确机制是未知的。这里,我们证明那高血压的段通过 VEGF 受体 2 调整 endothelial 房间(EC ) 的 WPB 的 exocytosis (VEGFR2 ) 表明小径。段触发一个快速的版本(在分钟以内) 从在有教养的人的 EC 的 WPB 的 von Willebrand 因素和 interleukin-8,通过 P-selectin 的 translocation 把在白血球和 EC 之间的相互作用提升到房间膜。我们进一步证明那高血压的段显著地导致未经触动的 EC 的 P-selectin translocation 并且两个都提高白血球粘附前 vivo 并且在 vivo。导致段的 endothelial exocytosis 经由 VEGFR2/PLCγ 被调停; 1/calcium 小径。有趣地,段也经由一条 VEGFR2/Akt/nitric 氧化物小径导致否定反馈。如此的双效果在颈动脉动脉片断,以及在尖锐高血压的老鼠模型用药理学和基因途径被证实。这些研究为 endothelial exocytosis 作为有势力收缩筋揭示机械段,它被 VEGFR2 发信号调制。因此, VEGFR2 发信号小径可以在限制高血压的段相关的发炎代表新奇治疗学的目标。 | Yan Xiong Zhenqian Hu Xiaofan Han Beibei Jiang Rongli Zhan Xiaoyu Zhang Yao Lu Chenyang Geng Wei Li Yulong He Yingqing Huo Masabuml Shlbuya Jincai Luo | 2013 | Cell Research2013，23，6： | 7 |
| 3 | Opening of the inward rectifier potassium channel alleviates maladaptive tissue repair following myocardial infarction显示文摘里面的整流器钾水流(IK1 ) 的激活隧道被报导了与室的心律不齐的抑制被联系。在这研究,我们测试了与 zacopride (ZAC ) IK1 隧道开在心肌的梗塞以后涉及织物修理的调整的假设。Sprague-Dawley 老鼠服从于冠的动脉结扎, ZAC intraperitoneally 被管理(15 諟?牦吗? | Chengfang Liu Enli Liu Tiane Luo Weifang Zhang Rongli He | 2016 | Acta Biochimica et Biophysica Sinica2016，48，8： | 4 |
| 4 | Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation显示文摘Accumulating evidence suggests that a reduction in the number of Foxp3^(+) regulatory T cells(Tregs)contributes to the pathogenesis of acute graft-versus-host disease(aGVHD),which is a major adverse complication that can occur after allogeneic hematopoietic stem cell transplantation(allo-HSCT).However,the precise features and mechanism underlying the defects in Tregs remain largely unknown.In this study,we demonstrated that Tregs were more dramatically decreased in bone marrow compared with those in peripheral blood from aGVHD patients and that bone marrow Treg defects were negatively associated with hematopoietic reconstitution.Tregs from aGVHD patients exhibited multiple defects,including the instability of Foxp3 expression,especially in response to IL-12,impaired suppressor function,decreased migratory capacity,and increased apoptosis.Transcriptional profiling revealed the downregulation of Lkb1,a previously identified critical regulator of murine Treg identity and metabolism,and murine Lkb1-regulated genes in Tregs from aGVHD patients.Foxp3 expression in human Tregs could be decreased and increased by the knockdown and overexpression of the Lkb1 gene,respectively.Furthermore,a loss-of-function assay in an aGVHD murine model confirmed that Lkb1 deficiency could impair Tregs and aggravate disease severity.These findings reveal that Lkb1 downregulation contributes to multiple defects in Tregs in human aGVHD and highlight the Lkb1-related pathways that could serve as therapeutic targets that may potentially be manipulated to mitigate aGVHD. | Xiuhua Su Qianqian Wang Wei Guo Xiaolei Pei Qing Niu Maolan Liu Yuanyuan Liu Song Chen Sizhou Feng Yi He Donglin Yang Rongli Zhang Qiaoling Ma Weihua Zhai Aiming Pang Jialin Wei Yong Huang Yuechen Luo Mingzhe Han Xiaoming Feng Erlie Jiang | 2020 | Cellular & Molecular Immunology2020，17，5： | 3 |
| 5 | The circFASN/miR-33a pathway participates in tacrolimusinduced dysregulation of hepatic triglyceride homeostasis显示文摘Dyslipidemia exhibits a high incidence after liver transplantation,in which tacrolimus,a widely used immunosuppressant,plays a fundamental role.MicroRNAs and related circRNAs represent a class of noncoding RNAs that have been recognized as important regulators of genes associated with lipid metabolism.However,their transcriptional activities and functional mechanisms in tacrolimus-related dyslipidemia remain unclear.In this study,we observed that tacrolimus could induce triglyceride accumulation in hepatocytes by stimulating sterol response element-binding proteins(SREBPs)and miR-33a.Our in silico and experimental analyses identified miR-33a as a direct target of circFASN.Tacrolimus could downregulate circFASN and result in elevated miR-33a in vivo and in vitro.Overexpression of circFASN or silencing of miR-33a decreased the promoting effects of tacrolimus on triglyceride accumulation.Clinically,the incidence of dyslipidemia in liver transplant recipients with elevated serum miR-33a after liver transplantation was higher than that in patients without elevated serum miR-33a(46.3%vs.18.8%p=0.012,n=73).Our results showed that the circFASN/miR-33a regulatory system plays a distinct role in tacrolimus-induced disruption of lipid homeostasis.MiR-33a is likely a risk factor for tacrolimus-related dyslipidemia,providing a potential therapeutic target to combat tacrolimus-induced dyslipidemia after liver transplantation. | Chenzhi Zhang Kangchen Chen Rongli Wei Guanghan Fan Xuechun Cai Li Xu Beini Cen Jianguo Wang Haiyang Xie Shusen Zheng Xiao Xu | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 2 |
| 6 | Different mechanisms of improving CH_(3)NH_(3)PbI_(3) perovskite solar cells brought by fluorinated or nitrogen doped graphdiyne显示文摘Fluorinated and nitrogen-doped graphdiyne(F/N-GDY)have been used in the active layer of perovskite solar cells(PSCs)for the first time.The introduction of heteroatoms turns out to be an effective method for boosted solar cells performance,which increases by 32.8%and 33.0%,better than the pristine or GDY doped PSCs.The enhanced performance can be attributed firstly to the superiority of F/N-GDY originated from the unique structure and optoelectronic properties of GDY.Then,both can further reduce surface defects and improve surface and bulk crystallinity than pristine GDY.What's more,efficiency increase caused by F-GDY is mainly attributed to the improvement of fill factor(FF),while the higher short-circuit current(Jsc)plays more important role by N-GDY doping.Most importantly,the detailed mechanism brought about by doping of F-GDY or N-GDY is expounded by systematical characterizations,especially the synchrotron radiation technique.Doping of F-GDY causes Pb and forms new Pb-F bonds between F-GDY and Pb ions.Doping of N-GDY or GDY brings about Pb(N-GDY doping induces more deviation than that of GDY due to the participation of imine N),improving its electron density and conductivity. | Huan Huang Bing Liu Dan Wang Rongli Cui Xihong Guo Ying Li Shouwei Zuo Zi Yin Huanhua Wang Jing Zhang Hui Yuan Lirong Zheng Baoyun Sun | 2022 | Nano Research2022，15，1： | 2 |
| 7 | Risk factors associated with hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation显示文摘Hemorrhagic cystitis(HC)is a common complication of allogeneic hematopoietic stem cell transplantation(HSCT).The incidence is about 7%to 68%,and some patients have to suffer a long period of frequent,urgent,and painful urination,which brings great pain.This study aimed to analyze risk factors of HC and its effect on patient survival.We collected the medical records of 859 patients who underwent HSCT at our hospital between August 2016 and August 2020.Patients with and without HC were matched using propensity score matching at a 1:1 ratio based on sex,age,and diagnosis,and logistic regression analyses were used to identify factors associated with HC.We used Kaplan–Meier curves to analyze the survival rates of patients in the HC and non-HC groups.We also analyzed the relationship between BK viral load and the occurrence of HC using receiver operating characteristic curve(ROC)analysis.After propensity score matching,there were 131 patients each in the HC and non-HC groups.In the HC group,89 patients(67.9%)had mild HC(stage II°)and 43(32.1%)had severe HC(stage III–IV).The median interval between stem cell transplantation and HC development was 31(3–244)days.Univariate analysis indicated that donor age,hematopoietic stem cell source,HLA,acute graft-versus-host disease,busulfan,anti-thymocyte globulin(ATG),total body irradiation,cytomegalovirus(CMV)(urine),and BK polyomavirus(BKV)(urine)were significantly associated with HC.ATG,CMV(urine),and BKV(urine)were independent risk factors for HC based on the multivariate analysis.The Kaplan–Meier survival analysis showed no significant difference between the HC and non-HC groups(P=0.14).The 1-and 2-year survival rates in the HC group were 78.4%and 69.6%,respectively,and the corresponding rates in the non-HC group were 84.4%and 80.7%,respectively.ROC analysis indicated that a urine BKV load of 1×10^(7) copies/mL was able to stratify the risk of HC.In conclusion,when the BKV load is>1×10^(7),we needtobe aware of the potential for the development of HC. | Biao Shen Yueshen Ma Haixiao Zhang Mingyang Wang Jia Liu Jiaxin Cao Wenwen Guo Dan Feng Donglin Yang Rongli Zhang Xin Chen Qiaoling Ma Weihua Zhai Sizhou Feng Mingzhe Han Aiming Pang Erlie Jiang 无 | 2022 | Blood Science2022，4，2： | 2 |
| 8 | Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents显示文摘新奇的碳 nanohybrids 成功地用作一个新磁性的回声成像 MRI 对比代理人基于未修改的 metallofullerenes 被制作了。nanohybrids 显示出更高的 R < 潜水艇 class= “ a-plus-plus ” > 1 relaxivity 和更好的使 Gd@C 明亮效果比 < 潜水艇 class= “ a-plus-plus ” > 82 哦 < 潜水艇 class= “ a-plus-plus ” > 在 T 的 X ,< 潜水艇 class= “ a-plus-plus ” > 在 vivo 的 1 幅 -weighted 先生图象。这是从原来的 gadofullerenes 的质子 relaxivity 的结果,它保留了完美的碳笼子结构可能完全那么避免 Gd 的版本 < 啜 class= “ a-plus-plus ” >3+ 个 离子。第二等的纺纱电子转移松驰机制被建议解释怎么 encaged Gd < 啜 class= “ a-plus-plus ” > 碳 nanohybrids 的 3+ 个 离子与包围的水分子交往。这条途径为开发高度有效、低的毒性 MRI 对比代理人打开新机会。 | Rongli Cui Juan Li Huan Huang Mingyi Zhang Xihong Guo Yanan Chang Min Li Jinquan Dong Baoyun Sun Gengmei Xing | 2015 | Nano Research2015，8，4： | 2 |
| 9 | 显示文摘 | Yu Ke Xu Rongli Zhang Yongsheng | 2005 | Solid State Communications2005，133，： | 1 |
| 10 | EasiTia: Apervasive traffic information acquisition system based onwireless sensor networks 显示文摘 | Wang Rui Zhang Lei Sun Rongli | 2011 | IEEETransonIntelligentTransportation Systems2011，12，2： | 1 |
| 11 | Influence of long-term nitrogen fertilization on micronutrient density in grain of winter wheat ( Triticum aestivum L.)显示文摘 | Rongli Shi Yueqiang Zhang Xinping Chen Qinping Sun Fusuo Zhang Volker R?mheld Chunqin Zou | 2009 | Journal of Cereal Science2009，，1： | 1 |
| 12 | Quartz Crystal Microbalance Coated with Carbon Nanotube Films Used as Humidity Sensor显示文摘 | Zhang Yongsheng Yu Ke Xu Rongli | 2005 | Sensors and Actuators A2005，120，： | 1 |
| 13 | A Pervasive Traffic Information Acquisition System Based on Wireless Sensor Networks 显示文摘 | Wang Rui Zhang Lei Sun Rongli | 2011 | IEEE Transactions on Intelligent Transportation Systems2011，12，2： | 1 |
| 14 | Liquid–liquid interfacial behavior of dopamine modifiedpoly(-glutamic acid)polymer显示文摘 | Rongli Zhang Ling Lin Sheng Xu | 2015 | Colloids and Surfaces A:Physicochemical and Engineering Aspects2015，470，21： | 1 |
| 15 | Identification of quantitative trait locus of zinc and phosphorus density in wheat (Triticum aestivum L.) grain显示文摘 | Rongli Shi Hongwei Li Yiping Tong Ruilian Jing Fusuo Zhang Chunqin Zou | 2008 | Plant and Soil (-)2008，，1： | 1 |
| 16 | One-pot synthesis of grass-like Fe 3 O 4 nanostructures by a novel microemulsion-assisted solvothermal method显示文摘 | Yanfen Li Rongli Jiang Tingyu Liu Hui Lv Lu Zhou Xiaoyu Zhang | 2013 | Ceramics International2013，，： | 1 |
| 17 | Eosinophilic gastroenteritis: Clinical manifestations and morphological characteristics, a retrospective study of 42 patients显示文摘 | Li Zhang Liping Duan Shigang Ding Jingjing Lu Zhu Jin Rongli Cui Michael McNutt Aiying Wang | 2011 | Scandinavian Journal of Gastroenterology2011，，9： | 1 |
| 18 | Androecious Genotype ‘Male 8' Carries the CPCNA Gene Locus Controlling Natural Deastringency of Chinese PCNA Persimmons显示文摘The androecious genotype of Diospyros spp. ‘Male 8', which is distributed in Dabie Mountain area of the central China, was probably derived from the hybrids or natural variation of Chinese pollination constant and non-astringent(CPCNA) persimmon. Its application potential as the breeding parent of pollination constant and non-astringent(PCNA) is undefined. In this study, we identified the astringency type of a hybrid individual(H8-2) derived from the cross between ‘Huashi 1'(pollination variant and astringent, PVA) and ‘Male 8'. Through comparison with the known genotypes of CPCNA, Japanese PCNA(JPCNA) and non-PCNA, the results of soluble/insoluble tannin content and tannin cell size measure showed that H8-2 was a PCNA genotype with the characteristic of natural deastringency of CPCNA. According to the currently known genetic features of PCNA persimmon, a new individual of PCNA may be generated in F1 population when two JPCNA genotypes are crossed or when the CPCNA genotype is used as a parent. Thus, the study verifies that androecious genotype ‘Male 8' carries the dominant gene locus that controls the non-astringent trait of CPCNA, indicating its potential to be used as pollen donor for the genetic improvement of PCNA persimmon. | ZHANG Na XU Junchi MO Rongli ZHANG Qinglin LUO Zhengrong | 2016 | Horticultural Plant Journal2016，2，6： | 1 |
| 19 | Identification of quantitative trait locus of zinc and phosphorus density in wheat (Triticum aestivum L.) grain显示文摘 | Rongli Shi Hongwei Li Yiping Tong Ruilian Jing Fusuo Zhang Chunqin Zou | 2008 | Plant and Soil (-)2008，，1： | 1 |
| 20 | Efficient field emission from tetrapod-like zinc oxide nanoneedles 显示文摘 | Ke Yu Yongsheng Zhang Rongli Xu | 2005 | Materials Letters2005，59，： | 1 |
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