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| 1 | Types,Characteristics and Significances of Migrating Pathways of Gas-bearing Fluids in the Shenhu Area,Northern Continental Slope of the South China Sea显示文摘The first marine gas hydrate expedition in China has been conducted by Guangzhou Marine Geological Survey in the Shenhu Area, northern continental slope of the South China Sea. Previous study has analyzed the P-T conditions, geophysical anomalies and saturation calculations of these gas hydrates, but has not documented in detail the migration of gas-bearing fluids in the study area. Based on the interpretations of 2D/3D seismic data, this work identified two types of migration pathways for gas-bearing fluids in the Shenhu area, i.e., vertical and lateral pathways. The vertical pathways(largescale faults, gas chimneys and mud diapirs) presented as steep seismic reflection anomalies, which could be traced downward to the Eocene source rocks and may penetrate into the Late Miocene strata. The deeper gases/fluids might be allowed migrating into the shallower strata through these vertical conduits. However, the distributions showed distinct differences between these pathways. Large-scale faults developed only in the north and northeast of the Shenhu area, while in the drilling area gas chimneys were the sole vertical migration pathways. Since the Pliocene, normal faults, detachment faults and favorable sediments have constituted the lateral pathways in the Shenhu gas hydrate drilling area. Although these lateral pathways were connected with gas chimneys, they exerted different effects on hydrate formation and accumulation. Gas-bearing fluids migrated upward along gas chimneys might further migrate laterally because of the normal faults, thereby enlarging the range of the chimneys. Linking gas chimneys with the seafloor, the detachment faults might act as conduits for escaping gases/fluids. Re-deposited sediments developed at the early stage of the Quaternary were located within the gas hydrate stability zone, so hydrates would be enriched in these favorable sediments. Compared with the migration pathways(large-scale faults and mud diapirs) in the LW3-1 deep-sea oil/gas field, the migration efficiency of the vertical pathways(composed of gas chimneys) in the gas hydrate drilling area might be relatively low. Description and qualitative discrimination of migration pathways in the Shenhu gas hydrate drilling area are helpful to further understand the relationship between good-quality deep source rocks and shallow, mainly biogenicallyproduced, hydrates. As the main source rocks of the Baiyun sag, lacustrine mudstones in the Wenchang and Enping Formations may provide thermogenic methane. Gas chimneys with relatively low migration efficiency created the vertical pathways. Caused by the Dongsha tectonic movement, the release of overpressured fluids might reduce the vertical migration rates of the thermogenic methane. The thick bathyal/abyssal fine-grained sediments since the Late Miocene provided migration media with low permeability. These preconditions may cause carbon isotopic fractionation ofthermogenic methane during long-distance vertical migrations. Therefore, although geochemical analyses indicate that the methane forming gas hydrate in the Shenhu area was mainly produced biogenically, or was mixed methane primarily of microbial origin, thermogenic methane still contribute significantly. | SU Ming SHA Zhibin ZHANG Cuimei WANG Hongbin WU Nengyou YANG Rui LIANG Jinqiang QIAO Shaohua CONG Xiaorong LIU Jie | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 16 |
| 2 | China's provincial CO2 emissions embodied in trade with implications for regional climate policy显示文摘 | Zhangqi ZHONG Rui HUANG Qinneng TANG Xiaonan CONG Zheng WANG | 2015 | Frontiers of Earth Science2015，9，1： | 14 |
| 3 | Antioxidant Effect of Human Selenium-containing Single-chain Fv in Rat Cardiac Myocytes显示文摘Reactive oxygen species(ROS) plays a key role in human heart diseases. Glutathione peroxidase(GPX) functions as an antioxidant as it catalyzes the reduction of hydroperoxide. In order to investigate the antioxidant effect of human selenium-containing single-chain Fv(Se-scFv-B3), a new mimic of GPX, a model system of hydrogen peroxide(H2O2)-induced rat cardiac myocyte damage was established. The cardiac myocyte damage was characterized in terms of cell viability, lipid peroxidation, cell membrane integrity, and intracellular H2O2 level. The Se-scFv-B3 significantly reduced H2O2-induced cell damage as shown by the increase of cell viability, the decline of malondialdehyde(MDA) production, lactate dehydrogenase(LDH) release, and intracellular H2O2 level. So Se-scFv-B3 may have a great potential in the treatment of human heart diseases induced by ROS. | HUO Rui SHI Yi XU Jun-jie YAN Fei LV Shao-wu SU Jia-ming DUAN Yu-jing FAN Jia NING Bo CONG Deng-li YAN Gang-lin LUO Gui-min WEI Jing-yan | 2009 | Chemical Research in Chinese Universities2009，25，2： | 8 |
| 4 | A cohort autopsy study defines COVID-19 systemic pathogenesis显示文摘Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied by dysfunction of the lungs and extrapulmonary organs.However,the organotropism of SARS-CoV-2 and the port of virus entry for systemic dissemination remain largely unknown.We profiled 26 COVID-19 autopsy cases from four cohorts in Wuhan,China,and determined the systemic distribution of SARS-CoV-2. | Xiao-Hong Yao Tao Luo Yu Shi Zhi-Cheng He Rui Tang Pei-Pei Zhang Jun Cai Xiang-Dong Zhou Dong-Po Jiang Xiao-Chun Fei Xue-Quan Huang Lei Zhao Heng Zhang Hai-Bo Wu Yong Ren Zhen-Hua Liu Hua-Rong Zhang Cong Chen Wen-Juan Fu Heng Li Xin-Yi Xia Rong Chen Yan Wang Xin-Dong Liu Chang-Lin Yin Ze-Xuan Yan Juan Wang Rui Jing Tai-Sheng Li Wei-Qin Li Chao-Fu Wang Yan-Qing Ding Qing Mao Ding-Yu Zhang Shu-Yang Zhang Yi-Fang Ping Xiu-Wu Bian | 2021 | Cell Research2021，31，8： | 7 |
| 5 | FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation显示文摘F 盒子和 WD 重复包含域 7 (FBW7 ) , E3 ubiquitin ligase SCF FBW7 (SKP1, cullin-1 和 FBW7 的建筑群) ,在各种各样的生理、病理学的过程起重要作用。尽管 FBW7 为脉管的开发被要求,它在内皮细胞层的函数尚待被调查。在这研究,我们证明 FBW7 是 endothelial 功能的一个重要管理者,包括 angiogenesis,白血球粘附和 endothelial 障碍正直。用 RNA 干扰,我们发现 FBW7 的弄空显著地在 vitro 并且在 vivo 损害 angiogenesis。我们识别了锌手指抄写因素 Krü象 ppel 一样因素 2 (KLF2 ) 作为在 endothelial 房间的 FBW7 的一个生理的目标。FBW7 击倒表示在 endothelial 房间导致了内长的 KLF2 蛋白质的累积。调停 FBW7 的 KLF2 破坏被显示在二保存 phosphodegrons 经由肝糖 synthase kinase-3 (GSK3 ) 取决于 KLF2 的 phosphorylation。变异这些 phosphodegron 主题废除了 KLF2 的调停 FBW7 的降级和 ubiquitination。调停 siRNA 显示出的 FBW7 击倒 KLF2 是在 endothelial 的规定的 FBW7 的一个必要目标,这工作。而且,调停 FBW7 的 KLF2 降级被显示为在 teratomas 并且在 zebrafish 开发的 angiogenesis 批评。一起拿,我们的学习在 endothelial 房间移植, angiogenesis,发炎和障碍完整的进程为 FBW7 建议一个角色,并且在 vivo 提供新奇卓见进 KLF2 稳定性的规定。 | Rui Wang Yah Wang Ning Liu Chunguang Ren Cong Jiang Kai Zhang Su Yu Yunfei Chen Hui Tang Qi Deng Cong Fu Yingcong Wang Rong Li Mingyao Liu Weijun Pan Ping Wang | 2013 | Cell Research2013，23，6： | 7 |
| 6 | Biological removal of antiandrogenic activity in gray wastewater and coking wastewater by membrane reactor process显示文摘A recombinant human androgen receptor yeast assay was applied to investigate the occurrence of antiandrogens as well as the mechanism for their removal during gray wastewater and coking wastewater treatment. The membrane reactor(MBR) system for gray wastewater treatment could remove 88.0% of antiandrogenic activity exerted by weakly polar extracts and 97.3% of that by moderately strong polar extracts, but only 32.5%of that contributed by strong polar extracts. Biodegradation by microorganisms in the MBR contributed to 95.9% of the total removal. After the treatment, the concentration of antiandrogenic activity in the effluent was still 1.05 μg flutamide equivalence(FEQ)/L, 36.2%of which was due to strong polar extracts. In the anaerobic reactor, anoxic reactor, and membrane reactor system for coking wastewater treatment, the antiandrogenic activity of raw coking wastewater was 78.6 mg FEQ/L, and the effluent of the treatment system had only 0.34 mg FEQ/L. The antiandrogenic activity mainly existed in the medium strong polar and strong polar extracts. Biodegradation by microorganisms contributed to at least 89.2%of the total antiandrogenic activity removal in the system. Biodegradation was the main removal mechanism of antiandrogenic activity in both the wastewater treatment systems. | Dehua Ma Lujun Chen Cong Liu Chenjun Bao Rui Liu | 2015 | Journal of Environmental Sciences2015，27，7： | 5 |
| 7 | Basal Serum Anti-Miillerian Hormone Level as a Predictor of Clinical Outcomes in Freezing-all Embryo Transfer Program显示文摘As a novel biomarker,there is inconsistent evidence regarding the association between anti-Miillerian hormone (AMH) and live birth rate in freezing-all embryo transfer cycles.We aim to assess the prognostic effect of baseline AMH on clinical outcomes,especially live birth rate in freezing-all embryo transfer cycles.A total of 828 non-polycystic ovary patients that underwent their first frozen-thawed embryo transfers in our center between January 2010 and January 2015 were recruited in this retrospective analysis.Patients were stratified into three groups based on their baseline AMH concentration:low AMH group (<1.4ng/mL),middle AMH group (1.4-5.8 ng/mL)and high AMH group (>5.8 ng/mL).The results showed that low AMH level was associated With adverse clinical outcomes.The differences in implantation rate (21.9% vs.43.2% vs.58.8%,P<0.001),clinical pregnancy rate (32.0% vs.55.2% vs.65.7%, P<0.001),live birth delivery rate (21.8% vs.43.6% vs.52.7%,P<0.001)and miscarriage rate (31.8% vs.17.5% vs.15.4%,P=0.014)among the three groups were statistically significant.After adjusting confounders (i.e.age,baseline FSH level,AFC,endometrium thickness,endometriurn preparation protocols,number of embryos transferred,etiologies of infertility),differences in live birth rate,clinical pregnancy rate and implantation rate between groups remained significant.The further age subgroup analysis demonstrated that low AMH concentration was significantly associated with poor outcomes both in young and advanced patients.The area under the curve for serum AMH,age,AFC and FSH were 0.635,0.634,0.615 and 0.543 respectively,for predicting live birth.In conclusion, baseline AMH was an independent prognostic factor of live birth rate of freezing-all embryo transfers,but its predictive value on live birth rate was of limited clinical value. | Xiao-lan LI Rui HUANG Cong FANG Xiao-yan LIANG | 2018 | Current Medical Science2018，38，5： | 5 |
| 8 | Multiple sgRNAs facilitate base editingmediated i-stop to induce complete and precise gene disruption显示文摘Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9)system has been demonstrated as a versatile tool for engineering eukaryote genome(Hsu et al.,2014),such as in mice(Zuo et al.,2017). | Kun Jia Zongyang Lu Fei Zhou Zhiqi Xiong Rui Zhang Zhiwei Liu Yu'e Ma Lei He Cong Li Zhen Zhu Dejing Pan Zhengxing Lian | 2019 | Protein & Cell2019，10，11： | 3 |
| 9 | Characterization of uncultivated magnetotactic bacteria from the sediments of Yuehu Lake, China显示文摘Marine magnetotactic bacteria were collected from the intertidal sediments of Yuehu Lake(China), where their abundance reached 103–104 ind./cm3. Diverse morphotypes of magnetotactic bacteria were observed, including cocci and oval, vibrio-, spirillum-, rod-, elliptical-, handle- and bar-shaped forms. The magnetococci were the most abundant, and had flagella arranged in parallel within a bundle. The majority of magnetosomes were arranged in one, two or multiple chains, although irregular arrangements were also evident. All the results of high-resolution transmission electron microscopy(HRTEM) analysis show that magnetosome crystals were composed of Fe3O4, and their morphology was specific to particular cell morphotypes. By the 16 S r RNA gene sequence analysis, we found fourteen operational taxonomic units(OTUs) which were related to magnetotactic bacteria. Among these, thirteen belonged to the Alphaproteobacteria and one to the Gammaproteobacteria.Compared with known axenic and uncultured marine magnetotactic bacteria, the 16 S r RNA gene sequences of most magnetotactic bacteria collected from the Yuehu Lake exhibited sequence identities ranging from 90.1% to96.2%(<97%). The results indicate that microbial communities containing previously unidentified magnetotactic bacteria occur in the Yuehu Lake. | DU Haijian ZHANG Rui ZHANG Wenyan XU Cong CHEN Yiran PAN Hongmiao ZHOU Ke WU Long-fei XIAO Tian | 2017 | Acta Oceanologica Sinica2017，36，2： | 3 |
| 10 | Damage evolution model of strain hardening cementitious composites under the uniaxial stress state显示文摘The deformation and damage behaviors of strain hardening cementitious composites(SHCC) under the uniaxial stress state were investigated in this paper.Two ductile failure-based constitutive models were introduced to describe the uniaxial tension and compression properties of SHCC only using a few parameters.The computation method of model parameters was developed to ease the simulation procedures.Damage evolution of the SHCC was simulated by the formulation of continuum damage mechanics subsequently.The results show that the proposed models fit the stress-strain curves reasonably well,and the damage variables show different growth rules under uniaxial tension and compression.It is concluded that the proposed method can not only simply simulate the constitutive behavior of SHCC with the reasonable accuracy but also capture the characteristic of material degradation. | Rui He Shuan-fa Chen Pei-liang Cong Shao-hua Ji | 2013 | International Journal of Minerals,Metallurgy and Materials2013，20，2： | 3 |
| 11 | Validity of the Patient-Generated Subjective Global Assessment(PG SGA)in Colorectal Cancer Patients in China显示文摘Objective The patient-generated subjective global assessment(PG-SGA)is a nutritional assessment tool specially designed for cancer patients.This study tested the validity of the PG-SGA for the nutritional assessment of colorectal cancer(CRC)patients in China.Methods A total of 8,093 Chinese patients with any stage CRC were enrolled in this cross-sectional,observational study.Within the first 48 hours of admission,patients were evaluated using the PG-SGA,nutritional risk screening 2002(NRS 2002),Karnofsky Performance Status(KPS),and some anthropometric parameters,including the triceps skinfold thickness(TSF),mid-arm circumference(MAC),mid-arm muscle circumference(MAMC),hand grip strength(HGS),maximum left calf circumference(MLCC),and maximum right calf circumference(MRCC),among others.Spearman’s correlation test was performed to analyze item-total score correlations and correlations between the total PG-SGA score and other parameters or performance scores,further testing convergent validity.The discriminative ability of the PG-SGA was measured by comparing different characteristics between several nutritional groups.A principal component analysis was performed with selected parameters to evaluate the construct validity.Results The average total PG-SGA score of all patients was 5.69±4.46,and they had a median age of 59 years(interquartile range(IQR),51-67 years)and an average body mass index(BMI)of 22.57±3.29 kg/m^(2).The item-total correlations of the total PG-SGA score between the global PG-SGA rating(Spearman,r=0.94)and PG-SGA score(patient-generated)(Spearman,r=0.97)were strong.Significant correlations were also found between the total PG-SGA score and other nutritional screening tools,including the BMI(Spearman,r=-0.26),KPS(Spearman,r=-0.36),and NRS 2002(Spearman,r=-0.47).Well-nourished(41.2%),mildly or moderately malnourished(35.3%)and severely malnourished(23.5%)groups defined according to the PG-SGA had significantly different characteristics.Patients with a worse nutritional status tended to have a decreased BMI(well-nourished,23.32 kg/m^(2)vs.mildly or moderately malnourished,22.52 kg/m^(2)vs.severely malnourished,21.35 kg/m^(2);P<0.001),hemoglobin,body fat mass,muscle mass,protein mass,TSF,MAC,HGS,MAMC,and MLCC,and a dramatically increased C-reactive protein level.The Kaiser-Meyer-Olkin measure was>0.7,and the P value of Bartlett’s test of sphericity was<0.001.One component was extracted by the principal component analysis,and the analysis showed that the total PG-SGA score explained the total variances of 97.3%.Conclusion The PG-SGA is a valid tool for evaluating the nutritional status for Chinese CRC patients. | Rui Kang Yin Ling Li Fu Ping Chen Zhen Ming Fu Hong Xia Xu Chun Hua Song Ming Hua Cong Han Ping Shi | 2021 | Journal of Nutritional Oncology2021，6，3： | 3 |
| 12 | Logistic Regression Analysis of Risk Factors Associated with Spontaneous Abortion after In Vitro Fertilization/Intracytoplasmic Sperm Injection-Embryo Transfer in Polycystic Ovary Syndrome Patients显示文摘Objective:To analyze spontaneous abortion rate and its associated risk factors in patients with polycystic ovary syndrome(PCOS)after in vitro fertilization/intracytoplasmic sperm injection-embryo transfer(IVF/ICSI-ET).Methods:This was a retrospective cohort study on 2,231 PCOS patients undergoing IVF/ICSI treatment.For comparison,we enrolled another 2,231 patients with tubular factors in control group.Spontaneous abortion rate and chromosomal abnormality rate were compared between the two groups.Furthermore,clinical data were compared between the patients with spontaneous abortion and those with ongoing pregnancy using univariate and multivariate analysis for risk factors of spontaneous abortion in PCOS patients.Results:Patients in the PCOS group had significantly higher spontaneous abortion rate(24.15%)than that in the control group(12.75%,P<0.001).Chromosomal abnormality rate was significantly lower in the PCOS group(36.05%,31/86)than in the control group(55.56%,50/90,P=0.009).In the PCOS group,patients with spontaneous abortion had significantly elder age,higher body mass index(BMI),and homeostasis model assessment for insulin resistance(HOMA-IR)than those with ongoing pregnancy.The logistic regression analysis confirmed that the age,BMI,and HOMA-IR were the risk factors of spontaneous abortion in the PCOS patients.There were no significant differences between groups in the type of cycles,the quality of embryos transferred,the number of embryos transferred,fasting blood glucose,fasting insulin,and so on.Conclusions:Compared with non-PCOS patients,PCOS patients had higher spontaneous abortion rate,but the chromosomal abnormality was not a major factor for the high spontaneous abortion rate in the PCOS patients.Age,BMI,and HOMA-IR were risk factors for spontaneous abortion after IVF/ICSI-ET in PCOS patients. | Xiao-Lan Li Rui Huang Cong Fang Yan-Fang Wang Xiao-Yan Liang | 2018 | Reproductive and Developmental Medicine2018，2，2： | 2 |
| 13 | Analysis on mechanism and key factors of surrounding rock instability in deeply inclined roadway affected by argillation and water seepage显示文摘Based on the characteristics of surrounding rocks for deeply inclined roadway affected by argillation and water seepage, a structure model of layer crack plate was established to analyze the shear sliding instability mechanism. Through solid mechanics analysis of anchored surrounding rock with defect from water seepage, combined with numerical analysis for instability mechanism under water seepage in deeply inclined roadway, key factors were proposed. Results show that with increasing height of layer crack plate, lateral buckling critical load value for high wall of the roadway decreases; there is a multistage distribution for tensile stress along the anchor bolt with defect under pulling state condition;groundwater seepage seriously affects the strength of surrounding rock of the roadway, to some extent the plastic zone of the high side rises up to 8 m. Finally some support strategies were proposed for the inclined roadway and successfully applied to Haoyuan coal mine in Tiela mining area,western China. | Ma Rui Li Guichen Zhang Nong Liu Cong Wei Yinghao Zhang Ming | 2015 | International Journal of Mining Science and Technology2015，25，3： | 2 |
| 14 | Heterogeneity of allocation promotes cooperation in public goods games显示文摘 | Chuang Lei Te Wu Jian-Yuan Jia Rui Cong Long Wang | 2010 | Physica A: Statistical Mechanics and its Applications2010，，21： | 2 |
| 15 | Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment显示文摘Decades have passed since the first nanoparticles-base medicine was approved for human cancer treatment, and the research and development of nanoparticles for drug delivery are always undergoing.Nowadays, the significant advances complicate nanoparticles’ branches, including liposomes, solid lipid nanoparticles, inorganic nanoparticles, micelles, nanovaccines and nano-antibodies, etc. These nanoparticles show numerous capabilities in treatment and diagnosis of stubborn diseases like cancer and neurodegenerative diseases, emerging as novel drug carriers or therapeutic agents in future. In this review, the complicated branches of nanoparticles are classified and summarized, with their property and functions concluded. Besides, there are also some delivery strategies that make nanoparticles smarter and more efficient in drug delivery, and frontiers in these strategies are also summarized in this review. Except these excellent works in newly-produced drug delivery nanoparticles, some points of view and future expectations are made in the end. | Rui Liu Cong Luo Zhiqing Pang Jinming Zhang Shaobo Ruan Meiying Wu Lei Wang Tao Sun Nan Li Liang Han Jinjin Shi Yuanyu Huang Weisheng Guo Shaojun Peng Wenhu Zhou Huile Gao | 2023 | Chinese Chemical Letters2023，34，2： | 2 |
| 16 | Purification, characterization and anticancer activity of a polysaccharide from Panax ginseng显示文摘 | Cong Li Jianping Cai Jingshu Geng Yinghong Li Zhenyu Wang Rui Li | 2012 | International Journal of Biological Macromolecules2012，，5： | 2 |
| 17 | Inverted U-Shaped Associations between Glycemic Indices and Serum Uric Acid Levels in the General Chinese Population:Findings from the China Cardiometabolic Disease and Cancer Cohort(4C)Study显示文摘Objective The relationship between serum uric acid(SUA)levels and glycemic indices,including plasma glucose(FPG),2-hour postload glucose(2 h-PG),and glycated hemoglobin(HbA1 c),remains inconclusive.We aimed to explore the associations between glycemic indices and SUA levels in the general Chinese population.Methods The current study was a cross-sectional analysis using the first follow-up survey data from The China Cardiometabolic Disease and Cancer Cohort Study.A total of 105,922 community-dwelling adults aged≥40 years underwent the oral glucose tolerance test and uric acid assessment.The nonlinear relationships between glycemic indices and SUA levels were explored using generalized additive models.Results A total of 30,941 men and 62,361 women were eligible for the current analysis.Generalized additive models verified the inverted U-shaped association between glycemic indices and SUA levels,but with different inflection points in men and women.The thresholds for FPG,2 h-PG,and HbA1 c for men and women were 6.5/8.0 mmol/L,11.0/14.0 mmol/L,and 6.1/6.5,respectively(SUA levels increased with increasing glycemic indices before the inflection points and then eventually decreased with further increases in the glycemic indices).Conclusion An inverted U-shaped association was observed between major glycemic indices and uric acid levels in both sexes,while the inflection points were reached earlier in men than in women. | ZHU Yuan Yue ZHENG Rui Zhi WANG Gui Xia CHEN Li SHI Li Xin SU Qing XU Min XU Yu CHEN Yu Hong YU Xue Feng YAN Li WANG Tian Ge ZHAO Zhi Yun QIN Gui Jun WAN Qin CHEN Gang GAO Zheng Nan SHEN Fei Xia LUO Zuo Jie QIN Ying Fen HUO Ya Nan LI Qiang YE Zhen ZHANG Yin Fei LIU Chao WANG You Min WU Sheng Li YANG Tao DENG Hua Cong ZHAO Jia Jun CHEN Lu Lu MU Yi Ming TANG Xu Lei HU Ru Ying WANG Wei Qing NING Guang LI Mian LU Jie Li BI Yu Fang | 2021 | Biomedical and Environmental Sciences2021，34，1： | 2 |
| 18 | Synthesis of monodispersed Fe3O4@C core/shell nanoparticles显示文摘We report a facile method to synthesize dispersed Fe_3O_4@C nanoparticles(NPs). Fe_3O_4 NPs were firstly prepared via the high temperature diol thermal decomposition method. Fe_3O_4@C NPs were fabricated using glucose as a carbon source by hydrothermal process. The obtained products were characterized by X-ray diffraction(XRD), transmission electron microscopy(TEM), vibrating sample magnetometer(VSM) and Raman spectra. The results indicate that the original shapes and magnetic property of Fe_3O_4 NPs can be well preserved. The magnetic particles are well dispersed in the carbon matrix. This strategy would provide an efficient approach for existing applications in Li-ion batteries and drug delivery. Meanwhile, it offers the raw materials to assemble future functional nanometer and micrometer superstructures. | Rui Liu Shu Mi Yuanyuan Li Cong Chen Yong Xie Qiang Chen Ziyu Chen | 2016 | Science China Chemistry2016，59，4： | 2 |
| 19 | Mitochondria-targeted ratiometric fluorescent probes for micropolarity and microviscosity and their applications显示文摘Two fluorescent“off-on”probes YYH1 and YYH2 were used for the detection of mitochondrial polarity and viscosity.Both probes have two emission bands:The peak of shorter wavelength was sensitive to the polarity,while that in longer wavelength region was sensitive to the viscosity,which enables us to detect medium polarity and viscosity simultaneously.The lg(Ishort/Ilong)of YYH1 exhibited linear relationship to the solvent polarity,while that of YYH2 was closely related to the solvent viscosity.Furthermore,both probes showed potential in bioimaging mitochondrial polarity or viscosity in living cells. | Jingjing Cui Yuhua Yao Cong Chen Rui Huang Weibing Zhang Junhong Qian | 2019 | Chinese Chemical Letters2019，30，5： | 2 |
| 20 | Proposal of a New Classification for Stage III Colorectal Cancer Based on the Number and Ratio of Metastatic Lymph Nodes显示文摘 | Li-Ping Wang Hong-Yan Wang Rui Cao Cong Zhu Xiong-Zhi Wu | 2013 | World Journal of Surgery2013，，5： | 1 |
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