|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Recent advances in the surgical treatment of hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is the most common primary liver malignancy. The treatment of HCC is complex and complicated by the severity of associated chronic liver disease, the stage of HCC, and the clinical condition of the patient. Liver resection(LR) is one of the most efficient treatments for patients with HCC, with an expected 5-year survival of 38%-61% depending on the stage of the disease. Improved liver function assessment, increased understanding of segmental liver anatomy from advanced imaging studies, and surgical technical progress are important factors that have led to reduced mortality in patients with HCC. The indication for LR may be expanded due to emerging evidences from laparoscopic hepatectomies and combined treatments with newly developed chemotherapies. Liver transplantation(LT) is considered as an ideal treatment for removal of existing tumors and the injured/preneoplastic underlying liver tissue with impaired liver function and the risk of multicentric carcinogenesis that results from chronically injured liver. However, LT is restricted to patients with minimal risk of tumor recurrence under immunosuppression. The expansion of criteria for LT in HCC patients is still under trial and discussion. Limited availability of grafts, as well as the risk and the cost of transplantation have led to considerable interest in expansion of the donor pool, living donor-related transplantation, and combined treatment involving LR and LT. This highlight presents evidence concerning recent studies evaluating LR and LT in HCC patients. In addition, alternative therapies for the treatment of early stage tumors and the management of patients on transplant waiting lists are discussed. | Zenichi Morise Norihiko Kawabe Hirokazu Tomishige Hidetoshi Nagata Jin Kawase Satoshi Arakawa Rie Yoshida Masashi Isetani | 2014 | World Journal of Gastroenterology2014，20，39： | 24 |
| 2 | Pure laparoscopic hepatectomy for hepatocellular carcinoma with chronic liver disease显示文摘Pure laparoscopic hepatectomy is a less invasive procedure than conventional open hepatectomy for the resection of hepatic lesions. Increases in experiences with the technique, in combination with advances in technology, have promoted the popularity of pure laparoscopic hepatectomy. However, indications for usage and potential contraindications of the procedure remain unresolved. The characteristics and specific advantages of the procedure, especially for hepatocellular carcinoma(HCC) patients with chronic liver diseases,are reviewed and discussed in this paper. For cirrhotic patients with liver tumors, pure laparoscopic hepatectomy minimizes destruction of the collateral blood and lymphatic flow from laparotomy and mobilization, and mesenchymal injury from compression. Therefore, pure laparoscopic hepatectomy has the specific advantage of minimal postoperative ascites production that leads to lowering the risk of disturbance in water or electrolyte balance and hypoproteinemia. It minimizes complications that routinely trigger postoperative serious liver failure. Under adequate patient positioning and port arrangement, the partial resection of the liver in the area of subphrenic space, peri-inferior vena cava area or next to the attachment of retro-peritoneum is facilitated in pure laparoscopic surgery by providing good vision and manipulation in the small operative field.Furthermore, the features of reduced post-operative adhesion, good vision, and manipulation within the small area between the adhesions make this procedure safer in the context of repeat hepatectomy procedures.These improved features are especially advantageous for patients with liver cirrhosis and multicentric and/or metachronous HCCs. | Zenichi Morise Norihiko Kawabe Jin Kawase Hirokazu Tomishige Hidetoshi Nagata Hisanori Ohshima Satoshi Arakawa Rie Yoshida Masashi Isetani | 2013 | World Journal of Hepatology2013，5，9： | 21 |
| 3 | Pure laparoscopic hepatectomy as repeat surgery and repeat hepatectomy显示文摘AIM:To assess clinical outcomes of laparoscopic hepatectomy(LH) in patients with a history of upper abdominal surgery and repeat hepatectomy.METHODS:This study compared the perioperative courses of patients receiving LH at our institution that had or had not previously undergone upper abdominal surgery.Of the 80 patients who underwent LH,22 had prior abdominal surgeries,including hepatectomy(n = 12),pancreatectomy(n = 3),cholecystectomy and common bile duct excision(n = 1),splenectomy(n = 1),total gastrectomy(n = 1),colectomy with the involvement of transverse colon(n = 3),and extended hysterectomy with extensive lymph-node dissection up to the upper abdomen(n = 1).Clinical indicators including operating time,blood loss,hospital stay,and morbidity were compared among the groups.RESULTS:Eighteen of the 22 patients who had undergone previous surgery had severe adhesions in the area around the liver.However,there were no conversions to laparotomy in this group.In the 58 patients without a history of upper abdominal surgery,the median operative time was 301 min and blood loss was 150 m L.In patients with upper abdominal surgical history or repeat hepatectomy,the operative times were 351 and 301 min,and blood loss was 100 and 50 m L,respectively.The median postoperative stay was 17,13 and 12 d for patients with no history of upper abdominal surgery,patients with a history,and patients with repeat hepatectomy,respectively.There were five cases with complications in the group with no surgical history,compared to only one case in the group with a prior history.There were no statistically significant differences in the perioperative results between the groups with and without upper abdominal surgical history,or with repeat hepatectomy.CONCLUSION:LH is feasible and safe in patients with a history of upper abdominal surgery or repeat hepatectomy. | Masashi Isetani Zenichi Morise Norihiko Kawabe Hirokazu Tomishige Hidetoshi Nagata Jin Kawase Satoshi Arakawa | 2015 | World Journal of Gastroenterology2015，21，3： | 13 |
| 4 | Caudal approach to pure laparoscopic posterior sectionectomy under the laparoscopy-specific view显示文摘AIM:To study our novel caudal approach laparoscopic posterior-sectionectomy with parenchymal transection prior to mobilization under laparoscopy-specific view.METHODS:Points of the procedure are:(1) Patients are put in left lateral position and posterior sector is not mobilized;(2) Glissonian pedicle of the sector is encircled and clamped extra-hepatically and divided afterward during the transection;(3) Dissection of inferior vena cava(IVC) anterior wall behind the liver is started from caudal.Simultaneously,liver transection is performed to search right hepatic vein(RHV) from caudal;(4) Liver transection proceeds to the bifurcation of the vessels from caudal to cranial,exposing the surfaces of IVC and RHV.Since the remnant liver sinks down,the cutting surface is well-opend;and(5) After the completion of transection,dissection of the resected liver from retroperitoneum is easily performed using the gravity.This approach was performed for a 63 years old woman with liver metastasis close to RHV.RESULTS:RHV exposure is required for R0 resection of the lesion.Although the cutting plane is horizontal in supine position and the gravity obstructs the exposure in the small subphrenic space,the use of specific characteristics of laparoscopic hepatectomy,such as the good vision for the dorsal part of the liver and IVC and facilitated dissection using the gravity with the patient positioning,made the complete RHV exposure during the liver transection easy to perform.The operation time was 341 min and operative blood loss was 1356 mL.Her postoperative hospital stay was uneventfull and she is well without any signs of recurrences 14 mo after surgery.CONCLUSION:The new procedure is feasible and useful for the patients with tumors close to RHV and the need of the exposure of RHV. | Hirokazu Tomishige Zenichi Morise Norihiko Kawabe Hidetoshi Nagata Hisanori Ohshima Jin Kawase Satoshi Arakawa Rie Yoshida Masashi Isetani | 2013 | World Journal of Gastrointestinal Surgery2013，5，6： | 7 |
| 5 | Small Bowel Injury by Low-Dose Enteric-Coated Aspirin and Treatment With Misoprostol: A Pilot Study显示文摘 | Toshio Watanabe Satoshi Sugimori Natsuhiko Kameda Hirohisa Machida Hirotoshi Okazaki Tetsuya Tanigawa Kenji Watanabe Kazunari Tominaga Yasuhiro Fujiwara Nobuhide Oshitani Kazuhide Higuchi Tetsuo Arakawa | 2008 | Clinical Gastroenterology and Hepatology2008，，11： | 2 |
| 6 | Advances in quantum dots for classical and non-classical light sources Invited Paper显示文摘Recent advances in quantum dots(QDs)for classical and non-classical light sources are presented.We have established metal organic chemical vapor deposition(MOCVD)technology for InAs-based QD lasers at 1.3μm and achieved ultralow threshold in QD lasers with photonic crystal(PhC)nanocavity.In addition, single photon emitters at 1.55μm,GaN-based single photon sources operating at 200 K,and high-Q PhC nanocavity have been demonstrated. | Yasuhiko Arakawa Satoshi Iwamoto Satoshi Kako Masahiro Nomura Denis Guimard | 2008 | Chinese Optics Letters2008，6，10： | 1 |
| 7 | Present status and strategy of NSAIDs-induced small bowel injury显示文摘 | Kazuhide Higuchi Eiji Umegaki Toshio Watanabe Yukiko Yoda Eijiro Morita Mitsuyuki Murano Satoshi Tokioka Tetsuo Arakawa | 2009 | Journal of Gastroenterology2009，，9： | 1 |
| 8 | Prevalence of mid-gastrointestinal bleeding in patients with acute overt gastrointestinal bleeding: multi-center experience with 1,044 consecutive patients显示文摘 | Hirotoshi Okazaki Yasuhiro Fujiwara Satoshi Sugimori Yasuaki Nagami Natsuhiko Kameda Hirohisa Machida Hirokazu Yamagami Tetsuya Tanigawa Masatsugu Shiba Kenji Watanabe Kazunari Tominaga Toshio Watanabe Nobuhide Oshitani Tetsuo Arakawa | 2009 | Journal of Gastroenterology2009，，6： | 1 |
| 9 | Restauro-G:A Rapid Genome Re-Annotation System for Comparative Genomics显示文摘Annotations of complete genome sequences submitted directly from sequencing projects are diverse in terms of annotation strategies and update frequencies. These inconsistencies make comparative studies difficult. To allow rapid data prepara- tion of a large number of complete genomes, automation and speed are impor- tant for genome re-annotation. Here we introduce an open-source rapid genome re-annotation software system, Restauro-G, specialized for bacterial genomes. Restauro-G re-annotates a genome by similarity searches utilizing the BLAST- Like Alignment Tool, referring to protein databases such as UniProt KB, NCBI nr, NCBI COGs, Pfam, and PSORTb. Re-annotation by Restauro-G achieved over 98% accuracy for most bacterial chromosomes in comparison with the original manually curated annotation of EMBL releases. Restauro-G was developed in the generic bioinformatics workbench G-language Genome Analysis Environment and is distributed at http://restauro-g.iab.keio.ac.jp/ under the GNU General Public License. | Satoshi Tamaki Kazuharu Arakawa Nobuaki Kono Masaru Tomita | 2007 | Genomics, Proteomics & Bioinformatics2007，5，1： | 1 |
| 10 | Discrete Differential Evolution for Mixed Discrete Non-Linear Problems显示文摘 | Satoshi Kitayama Masao Arakawa Koetsu Yamazaki | 2012 | Journal of Civil Engineering and Architecture2012，6，5： | 1 |
| 11 | Present status and strategy of NSAIDs-induced small bowel injury显示文摘 | Kazuhide Higuchi Eiji Umegaki Toshio Watanabe Yukiko Yoda Eijiro Morita Mitsuyuki Murano Satoshi Tokioka Tetsuo Arakawa | 2009 | Journal of Gastroenterology2009，，9： | 1 |
| 12 | Risk factors for deterioration of long-term liver function after radiofrequency ablation therapy显示文摘AIM:To identify factors that influence long-term liver function following radiofrequency ablation(RFA)in patients with viral hepatitis-related hepatocellular carcinoma.METHODS:A total of 123 patients with hepatitis B virus-or hepatitis C virus-related hepatocellular carcinoma(HCC)(n=12 and n=111,respectively)were enrolled.Cumulative rates of worsening Child-Pugh(CP)scores(defined as a 2-point increase)were examined.RESULTS:CP score worsening was confirmed in 22patients over a mean follow-up period of 43.8±26.3mo.Multivariate analysis identified CP class,platelet count,and aspartate aminotransferase levels as significant predictors of a worsening CP score(P=0.000,P=0.011 and P=0.024,respectively).In contrast,repeated RFA was not identified as a risk factor for liver function deterioration.CONCLUSION:Long-term liver function following RFA was dependent on liver functional reserve,the degreeof fibrosis present,and the activity of the hepatitis condition for this cohort.Therefore,in order to maintain liver function for an extended period following RFA,suppression of viral hepatitis activity is important even after the treatment of HCC. | Koichi Honda Masataka Seike Junya Oribe Mizuki Endo Mie Arakawa Hiroki Syo Masao Iwao Masanori Tokoro Junko Nishimura Tetsu Mori Tsutomu Yamashita Satoshi Fukuchi Toyokichi Muro Kazunari Murakami | 2016 | World Journal of Hepatology2016，8，13： | 1 |
| 13 | Use of capsule endoscopy in patients with C rohn’s disease in J apan: A multicenter survey显示文摘 | Motohiro Esaki Takayuki Matsumoto Kenji Watanabe Tetsuo Arakawa Yuji Naito Minoru Matsuura Hiroshi Nakase Toshifumi Hibi Takayuki Matsumoto Sadaharu Nouda Kazuhide Higuchi Naoki Ohmiya Hidemi Goto Sei Kurokawa Satoshi Motoya Mamoru Watanabe | 2014 | J Gastroenterol Hepatol2014，，1： | 1 |
| 14 | How Far Can We Go with Laparoscopic Liver Resection for Hepatocellular Carcinoma? Laparoscopic Sectionectomy of the Liver Combined with the Resection of the Major Hepatic Vein Main Trunk显示文摘 | Zenichi Morise Norihiko Kawabe Hirokazu Tomishige Hidetoshi Nagata Jin Kawase Satoshi Arakawa Masashi Isetani Junyong Park | 2015 | BioMed Research International2015，，： | 1 |
| 15 | Phase II trial of paclitaxel and nedaplatin in patients with advanced/recurrent uterine cervical cancer: A Kansai Clinical Oncology Group study显示文摘 | Munetaka Takekuma Yasuyuki Hirashima Kimihiko Ito Hiroshi Tsubamoto Tsutomu Tabata Atsushi Arakawa Yoshio Itani Naoto Furukawa Homare Murakoshi Satoshi Takeuchi | 2012 | Gynecologic Oncology2012，，3： | 1 |
| 16 | Characteristics of Macrolide‐Resistant Mycoplasma pneumoniae Strains Isolated from Patients and Induced with Erythromycin In Vitro显示文摘 | Norio Okazaki Mitsuo Narita Satoshi Yamada Kinichi Izumikawa Masao Umetsu Tsuyoshi Kenri Yuko Sasaki Yoshichika Arakawa Tsuguo Sasaki | 2001 | Microbiology and Immunology2001，，8： | 1 |
| 17 | Case report of the fourth laparoscopic liver resection and review of repeat laparoscopic resection for recurrent hepatocellular carcinoma in cirrhotic liver显示文摘A 73-year-old woman with liver cirrhosis caused by hepatitis C virus(HCV)underwent treatment of three hepatocellular carcinomas(HCCs)in liver segment 4,following three previous laparoscopic liver resections(LLRs)over 73 months.Contrast-enhanced computed tomography showed three 0.5-1.2 cm HCCs deep within the portal territories of subsegments 4a and 4b.The patient underwent laparoscopic resection of 4a and 4b,with the preservation of the portal branch to 4c,after minimal adhesiolysis around segment 4.The operation lasted 284 min,there was 50 mL of intra-operative bleeding and her recovery was uneventful.She was well,had experienced no recurrence and was HCV-negative,after taking oral anti-HCV therapy,21 months later.LLR is associated with fewer adhesions after surgery and requires less adhesiolysis,because the laparoscope and forceps can be used in the small spaces between adhesions.The present patient underwent four LLRs over 6 years without severe deterioration of liver functional reserve.LLR is a useful localized therapy,which can be performed repeatedly and may prolong the survival of patients with multicentric metachronous HCCs. | Zenichi Morise Masashi Isetani Norihiko Kawabe Hirokazu Tomishige Hidetoshi Nagata Satoshi Arakawa Masahiro Ikeda Kenshiro Kamio | 2016 | Hepatoma Research2016，2，1： | 1 |
| 18 | Laparoscopic liver resection for the treatment of hepatocellular carcinoma显示文摘Accumulation of experiences and technological advances after the first report of laparoscopic liver resection(LLR) are now revealing the characteristics and specific advantages of this approach, especially for hepatocellular carcinoma(HCC) patients with chronic liver diseases(CLD). Inlaparoscopic approach, there are minimum needs for:(1) laparotomy and dissection of the attachments and adhesion which may cause destructions in the collateral blood and lymphatic flows; and(2) compression of the liver which may cause parenchymal damage for the liver resection(LR). These are especially beneficial for the patients with CLD. LLR results in minimal postoperative ascites and the other complications, which could potentially lead to lowering the risk of fatal liver failure. These characteristics of LLR facilitate surgical treatment application to the patients of HCC with background CLD. Laparoscopic approach also results in improved vision and manipulation in a small operative field under several conditions, including the cases where it is necessary to perform repeat LR between adhesions. These characteristics make LLR safer and more accessible to the repeat treatment, such as multicentric and metachronous lesions in the cirrhotic liver. These advantages of LLR indicate it is a superior method than open LR under certain conditions in patients of HCC with background CLD. | Norihiko Kawabe Zenichi Morise Hirokazu Tomishige Hidetoshi Nagata Jin Kawase Satoshi Arakawa Masashi Isetani | 2015 | World Journal of Surgical Procedures2015，5，1： | 1 |
| 19 | Motion reconstruction of the small carry-on impactor aboard Hayabusa2显示文摘Subsurface exploration is one of the most ambitious scientific objectives of the Hayabusa2 mission.A small device called small carry-on impactor(SCI)was developed to create an artificial crater on the surface of asteroid Ryugu.This enables us to sample subsurface materials,which will provide a window to the past.The physical properties of the resulting crater are also useful for understanding the internal structure of Ryugu.Accurate understanding of the crater and ejecta properties,including the depth of excavation of subsurface materials,requires accurate information on impact conditions.In particular,the impact angle is a critical factor because it greatly influences the size and shape of the crater.On April 5,2019,the Hayabusa2 spacecraft deployed the SCI at 500 m of altitude above the asteroid surface.The SCI gradually reduced its altitude,and it shot a 2 kg copper projectile into the asteroid 40 min after separation.Estimating the position of the released SCI is essential for determining the impact angle.This study describes the motion reconstruction of the SCI based on the actual operation data.The results indicate that the SCI was released with high accuracy. | Takanao Saiki Yuya Mimasu Yuto Takei Manabu Yamada Hirotaka Sawada K azunori Ogawa Naoko Ogawa Hiroshi Takeuchi Akira Miura Yuri Shimaki Koji Wada Rie Honda Yasuhiro Yokota Kei Shirai Naruhisa Sano Hirohito Ohtsuka Go Ono Kent Yoshikawa Shota Kikuchi Chikako Hirose Yukio Yamamoto Takahiro Iwata Masahiko Arakawa Seiji Sugita Satoshi Tanaka Fuyuto Terui Makoto Yoshikawa Satoru Nakazawa Sei-ichiro Watanabe Yuichi Tsuda | 2020 | Astrodynamics2020，4，4： | 0 |
| 20 | Surgery for pancreatic tumors in the midst of COVID-19 pandemic显示文摘The spread of the new coronavirus(COVID-19)infection in 2020 has had a significant impact on the treatment of cancer worldwide.During the COVID-19 pandemic,the biggest challenge for pancreatic surgeons is the difficulty in providing oncological care.In this review article,from the standpoint of surgeons,we explain the concept of triaging of patients with pancreatic tumors under the COVID-19 pandemic,and the actual impact of COVID-19 on the treatment of patients with pancreatic tumors.The most vital points in selecting the best therapeutic approach for patients with pancreatic tumors during this pandemic are(1)Oncologists need to tailor the treatment plan based on the COVID-19 phase,tumor malignant potential,and patients’comorbidities;and(2)Optimal treatment for pancreatic cancer should be planned according to the condition of each patient and tumor resectability based on national comprehensive cancer network resectability criteria.To choose the best therapeutic approach for patients with pancreatic tumors during this pandemic,we need to tailor the treatment plan based on elective surgery acuity scale(ESAS).Newly established ESAS for pancreatic tumor and flowchart indicating the treatment strategy of pancreatic cancer,are feasible to overcome this situation. | Hiroyuki Kato Yukio Asano Satoshi Arakawa Masahiro Ito Norihiko Kawabe Masahiro Shimura Chihiro Hayashi Takayuki Ochi Hironobu Yasuoka Takahiko Higashiguchi Yuka Kondo Hidetoshi Nagata Akihiko Horiguchi | 2021 | World Journal of Clinical Cases2021，9，18： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员