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| 1 | Effect of wet flue gas desulfurization(WFGD) on fine particle(PM_(2.5)) emission from coal-fired boilers显示文摘In this study, the characteristics of fine particles before and after wet flue gas desulfurization(WFGD) in three coal-fired heating boilers in northern China were investigated by using a dilution-based emission sampling experimental system. The influences of the WFGD process on the mass and number concentrations as well as the chemical composition of fine particles were analyzed. The removal efficiency of desulfurization processes on particulate matter mass was 30.06%–56.25% for the three study units. The WFGD had a great influence on the size distributions of particle mass concentration and number concentration. A significant increase in the number and mass concentration of particles in the size range of 0.094–0.946 μm was observed. The watersoluble ion content accounted for a very large proportion of PM_(2.5) mass, and its proportion in PM_(2.5) increased from 28.39%–41.08% to 48.96%–61.21% after the WFGD process for the three units. The desulfurizing process also drastically increased the proportion of cation component(Ca^(2+) for unit A, Mg^(2+) for unit B, and Na+for unit C) and the proportion of SO_4^(2-) in PM_(2.5), and it increased the CE/AE values of PM_(2.5) from 0.82–0.98 to 0.93–1.27 for the three study units. | Sen Yao Shuiyuan Cheng Jianbing Li Hanyu Zhang Jia Jia Xiaowei Sun | 2019 | Journal of Environmental Sciences2019，31，3： | 8 |
| 2 | Heat shock protein 90 promotes RNA helicase DDX5 accumulation and exacerbates hepatocellular carcinoma by inhibiting autophagy显示文摘Objective:Hepatocellular carcinoma(HCC),the main type of liver cancer,has a high morbidity and mortality,and a poor prognosis.RNA helicase DDX5,which acts as a transcriptional co-regulator,is overexpressed in most malignant tumors and promotes cancer cell growth.Heat shock protein 90(HSP90)is an important molecular chaperone in the conformational maturation and stabilization of numerous proteins involved in cell growth or survival.Methods:DDX5 m RNA and protein expression in surgically resected HCC tissues from 24 Asian patients were detected by quantitative real-time PCR and Western blot,respectively.The interaction of DDX5-HSP90 was determined by molecular docking,immunoprecipitation,and laser scanning confocal microscopy.The autophagy signal was detected by Western blot.The cell functions and signaling pathways of DDX5 were determined in 2 HCC cell lines.Two different murine HCC xenograft models were used to determine the function of DDX5 and the therapeutic effect of an HSP90 inhibitor.Results:HSP90 interacted directly with DDX5 and inhibited DDX5 protein degradation in the AMPK/ULK1-regulated autophagy pathway.The subsequent accumulation of DDX5 protein induced the malignant phenotype of HCC by activating theβ-catenin signaling pathway.The silencing of DDX5 or treatment with HSP90 inhibitor both blocked in vivo tumor growth in a murine HCC xenograft model.High levels of HSP90 and DDX5 protein were associated with poor prognoses.Conclusions:HSP90 interacted with DDX5 protein and subsequently protected DDX5 protein from AMPK/ULK1-regulated autophagic degradation.DDX5 and HSP90 are therefore potential therapeutic targets for HCC. | Ting Zhang Xinrui Yang Wanping Xu Jing Wang Dawei Wu Zhixian Hong Shengxian Yuan Zhen Zeng Xiaodong Jia Shanshan Lu Rifaat Safadi Sen Han Zhihong Yang Leonard M.Neckers Suthat Liangpunsakul Weiping Zhou Yinying Lu | 2021 | Cancer Biology & Medicine2021，18，3： | 7 |
| 3 | Large-scale blow spinning of heat-resistant nanofibrous air filters显示文摘Particulate matter(PM)pollution has become a serious problem worldwide and various kinds of nanofibrous filters aiming to solve the problem have been developed.It is urgent to remove PM from high-temperature pollution sources,such as industrial emissions,coal furnaces,and automobile exhaust gases.However,filtration at pollution sources remains challenging because most existing air filters are not resistant to high temperature.Herein,heat-resistant polyimide(PI)nanofibrous air filters are fabricated via a simple and scalable solution blow-spinning method.These air filters show excellent thermal stability at high temperature up to 420℃.They exhibit a filtration efficiency as high as 99.73%at ambient temperature and over 97%at 300℃.In addition,a field test shows that the filters remove>97%of PM from the car exhaust fumes.Hence,the blow-spun PI nanofibrous membranes combined with the facile preparation strategy have great potential in high temperature air filtration fields and other similar applications such as water purification and protein separation. | Ziwei Li Jianan Song Yuanzheng Long Chao Jia Zhenglian Liu Lei Li Cheng Yang Junchen Liu Sen Lin Haiyang Wang Yibo Liu Minghao Fang Hui Wu | 2020 | Nano Research2020，13，3： | 6 |
| 4 | Interaction between the atmospheric boundary layer and a standalone wind turbine in Gansu—Part I: Field measurement显示文摘 | De Shun Li Tao Guo Yin Ran Li Jin Sen Hu Zhi Zheng Ye Li Yu Jia Di WenRui Hu RenNian Li | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，9： | 6 |
| 5 | Biotemplated synthesis of three-dimensional porous MnO/C-N nanocomposites from renewable rapeseed pollen: An anode material for lithium-ion batteries显示文摘锂离子电池(解放) 当前作为可得到的最流行的力量来源之一被认出。到预付展出长期的耐力的解放的构造,大注意对提高他们的差的周期稳定性被给予了。因为解放的表演依赖于采用的电极材料,改进他们的寿命的最有希望的途径是新奇电极材料的设计。我们此处描述合理设计一三维(3D ) 是的多孔的 MnO/C-N nanoarchitecture 为长周期生活解放的阳极材料基于他们从经由一条灵巧的退火沉浸的线路的便宜、可更新、丰富的油菜籽花粉(R 花粉) 的准备。显著地,有它的优化 3D nanostructure 的同样准备的 MnO/C-N 展出了一个高特定的能力(756.5 | Li-Feng Chen Sheng-Xiang Ma Shu Lu Yue Feng Jia Zhang Sen Xin Shu-Hong Yu | 2017 | Nano Research2017，10，1： | 5 |
| 6 | Classification of cultivated Chinese medicinal plants based on fractal theory and gray level co-occurrence matrix textures显示文摘 | ZHENG Shudan ZHENG Jianghua SHI Minghui GUO Baolin SEN Bati SUN Zhiqun JIA Xiaoguang LI Xiaojin | 2014 | 遥感学报2014，18，4： | 5 |
| 7 | TOTAL SYNTHESIS OF CLAUSENAMIDE显示文摘TOTAL SYNTHESIS OF CLAUSENAMIDETOTALSYNTHESISOFCLAUSENAMIDE￥ErChangRAO;HaoHONG;JiaChongCHENG;GuangZhongYANG;HanSenLIN;andLian... | Er Chang RAO Hao HONG Jia Chong CHENG Guang Zhong YANG Han Sen LIN andLiang HUANG(Institute of Mareia Medica. Chinese Academy of Medical Sciences1 Xian Nong Tan St .Beijing 100050) | 1994 | Chinese Chemical Letters1994，5，4： | 4 |
| 8 | A Comparative Study on the Nonspecific Immunity of Juvenile Litopenaeus vannamei ever Inhabiting Freshwater and Seawater显示文摘A study on the nonspecific immunity of Litopenaeus vannamei ever inhabiting freshwater and seawater was carried out at different molt stages by comparing their total hemocyte count(THC) and respiratory burst(RB) and activity of phenol oxidase(PO), nitric oxide synthase(NOS) and lysozyme(LY). Two-way ANOVA showed that salinity and molt stage independently affected THC and RB and the activity of PO, NOS and LY of juvenile L. vannamei significantly(P < 0.05). The THC and RB and the activity of NOS gradually increased from the post-molt stages(A and B) to the pre-molt stages(D0–D3), which were common in shrimps inhabiting freshwater and seawater. The activity of PO peaked at the inter-molt stage(C), and touched the lowest at the post-molt stage in freshwater and pre-molt stage in seawater. The activity of LY was stable over the molt cycle. The RB and the activity of PO, NOS and LY of juvenile L. vannamei were significantly lower in freshwater than in seawater; whereas THC was significantly higher in freshwater than in seawater(P < 0.05). It was concluded that the post-molt stage(especially stage A) was critical to shrimp culture, which should be intensively attended when L. vannamei was cultured in freshwater. | JIA Xuying DING Sen WANG Fang DONG Shuanglin | 2014 | Journal of Ocean University of China2014，13，3： | 3 |
| 9 | Rapid and Sparse Labeling of Neurons Based on the Mutant Virus-Like Particle of Semliki Forest Virus显示文摘Sparse labeling of neurons contributes to uncovering their morphology, and rapid expression of a fluorescent protein reduces the experiment range. To achieve the goal of rapid and sparse labeling of neurons in vivo, we established a rapid method for depicting the fine structure of neurons at 24 h post-infection based on a mutant viruslike particle of Semliki Forest virus. Approximately 0.014 fluorescent focus-forming units of the mutant virus-like particle transferred enhanced green fluorescent protein into neurons in vivo, and its affinity for neurons in vivo was stronger than for neurons in vitro and BHK21(baby hamster kidney) cells. Collectively, the mutant virus-likeparticle provides a robust and convenient way to reveal the fine structure of neurons and is expected to be a helper virus for combining with other tools to determine their connectivity. Our work adds a new tool to the approaches for rapid and sparse labeling of neurons in vivo. | Fan Jia Xutao Zhu Pei Lv Liang Hu Qing Liu Sen Jin Fuqiang Xu | 2019 | Neuroscience Bulletin2019，35，3： | 3 |
| 10 | The MING proposal at SHINE:megahertz cavity enhanced X‑ray generation显示文摘The cavity-based X-ray free-electron laser(XFEL)has promise in producing fully coherent pulses with a bandwidth of a few meV and very stable intensity,whereas the currently existing self-amplified spontaneous emission(SASE)XFEL is capable of generating ultra-short pulses with chaotic spectra.In general,a cavity-based XFEL can provide a spectral brightness three orders of magnitude higher than that of the SASE mode,thereby opening a new door for cutting-edge scientific research.With the development of superconducting MHz repetition-rate XFEL facilities such as FLASH,European-XFEL,LCLS-II,and SHINE,practical cavity-based XFEL operations are becoming increasingly achievable.In this study,megahertz cavity enhanced X-ray generation(MING)is proposed based on China’s first hard XFEL facility-SHINE,which we refer to as MING@SHINE. | Nan‑Shun Huang Zi‑Peng Liu Bang‑Jie Deng Zi‑Han Zhu Shao‑Hua Li Tao Liu Zheng Qi Jia‑Wei Yan Wei Zhang Sheng‑Wang Xiang Yang‑Yang Lei Ya Zhu Yong‑Zhou He Qi‑Bing Yuan Fei Gao Rong‑Bing Deng Sen Sun Zhi‑Di Lei Zhi‑Qiang Jiang Meng‑Qi Duan Yuan Zhuan Xue‑Fang Huang Peng‑Cheng Dong Zhong‑Liang Li Shang‑Yu Si Lian Xue Si Chen Yong‑Fang Liu Ya‑Jun Tong Hai‑Xiao Deng Zhen‑Tang Zhao | 2023 | Nuclear Science and Techniques2023，34，1： | 2 |
| 11 | Effects of Ligustrazine Combined with Cisdichlorodiamine Platinum on Anti-proliferation,Cell Cycle and Apoptosis of Human Gastric Carcinoma SGC-7901 Cell Lines显示文摘[Objective] This study aimed to investigate the combination effects of ligustrazine and cis-dichlorodiamine platinum(DDP) on anti-proliferation, cell cycle and apoptosis of SGC-7901 cell lines in vitro. [Method] SGC-7901 cells were treated with ligustrazine and DDP alone or combined for 48 h for morphology assay.Anti-proliferative effects with the same treatment for 24, 48 and 72 h were assayed by MTT method, respectively. Cell cycle distribution and apoptosis assay of treated cells were performed in flow cytometry. Zhengjun Jin's protocol was used to assay the effect of drug combination. [Result] Ligustrazine significantly increased the proliferation inhibition rate of DDP on SGC-7901 cells in combination with DDP, comparing with the effects of ligustrazine or DDP alone, and exhibited synergistic antitumor effect. The combination drug treatment induced cell cycle arrest occurred in S and G2 phase of the cell cycle and increased the apoptosis rate significantly.[Conclusion] Our results indicate that ligustrazine, as a low-toxic and natural herbal component, can significantly increase the anti-proliferative effect and apoptosis rate of antitumor drug DDP on human gastric carcinoma SGC-7901 cells. | Liyan LI Tao HUANG An JIA Huili HOU Sen PANG Yuzhen WANG | 2014 | Agricultural Science & Technology2014，15，9： | 2 |
| 12 | Analyzing peer-to-peer traffic across large networks显示文摘 | Subhabrata Sen Jia Wang | 2004 | IEEE/ACM Transactions on Networking (TON)2004，，2： | 2 |
| 13 | Hydrogen isotope effects: A new path to high-energy aqueous rechargeable Li/Na-ion batteries显示文摘Aqueous rechargeable Li/Na-ion batteries have shown promise for sustainable large-scale energy storage due to their safety,low cost,and environmental benignity.However,practical applications of aqueous batteries are plagued by water's intrinsically narrow electrochemical stability window,which results in low energy density.In this perspective article,we review several strategies to broaden the electrochemical window of aqueous electrolytes and realize high-energy aqueous batteries.Specifically,we highlight our recent findings on stabilizing aqueous Li storage electrochemistry using a deuterium dioxide-based aqueous electrolyte,which shows significant hydrogen isotope effects that trigger a wider electrochemical window and inhibit detrimental parasitic processes. | Xue-Ting Li Jia Chou Yu-Hui Zhu Wen-Peng Wang Sen Xin Yu-Guo Guo | 2023 | eScience2023，3，3： | 2 |
| 14 | Spectral and spatial complexitybased hyperspectral unmixing显示文摘 | Jia Sen Qian Yuntao | | 0，，12： | 1 |
| 15 | Analyzing peer-to-peer traffic across large networks显示文摘 | Subhabrata Sen Jia Wang | 2004 | IEEE/ACM Transactions on Networking (TON)2004，，2： | 1 |
| 16 | Hyperspeetral Unmixing via L1/2 Sparsity-Constrained Nonnegative Matrix Factorization 显示文摘 | QIAN Yuntao JIA Sen ZHOU Jun | 2011 | IEEE Trans Geo Remote Se2011，49，11： | 1 |
| 17 | Reverse Transcription Recombinase Polymerase Amplification Assays for Rapid Detection of Tick-Borne Encephalitis Virus Infection显示文摘Dear Editor,Tick-borne encephalitis virus(TBEV)belongs to the genus Flavivirus within the family Flaviviridae and includes three subtypes:Siberian,European,and Far Eastern.TBEV infects humans via tick bites;indeed,at least 10,000 human cases of encephalitis caused by TBEV are reported annually in Russia,China,and European countries(Banzhoff et al.2008;Carletti et al.2017). | Jia Jia Yuchang Li Xiaoyan Wu Sen Zhang Yi Hu Jing Li Tao Jiang Xiaoping Kang | 2019 | Virologica Sinica2019，34，3： | 1 |
| 18 | Analyzing Peer-to-Peer Traffic Across Large Networks显示文摘 | Shubho Sen Jia Wang | 2004 | ACM/IEEE Transactions on Networking2004，12，2： | 1 |
| 19 | Effects of transverse magnetic field during directional solidification of monotectic Al-6.5wt%Bi alloy显示文摘 | Sen Yang Wenjin Liu Jun Jia | 2001 | Journal of Materials Science2001，，22： | 1 |
| 20 | Effect of Pingan Fang, a Traditional Chinese Medicine compound, on behavioral sensitization and conditioned place preference induced by ethanol in mice显示文摘OBJECTIVE:To observe the effect of Pingan Fang(PG)on behavioral sensitization and conditioned place preference(CPP)induced by ethanol in mice,and to determine the intervention mechanism of PG on alcohol addiction.METHODS:A behavioral sensitization mouse model induced by ethanol was established to observe the effect of PG on the development and expression of behavioral sensitization induced by ethanol by recording the spontaneous activity of mice.The resident time of mice in a white box was measured to evaluate the effect of PG on developing CPP induced by ethanol.Concentrations of dopamine(DA),Glutamate(Glu),and?-aminobutyric acid(GABA)in the corresponding mesolimbic region of mice were determined by enzyme-linked immunosorbent assay.RESULTS:Although PG did not alter spontaneous activity in mice,it reduced the growth of spontaneous activity stimulated by ethanol.The residence time in the white box after-ethanol-training of mice in CPP experiments was decreased.CONCLUSION:Our data suggested that PG blocked the development and expression of behavioral sensitization induced by ethanol and the development of CPP in mice.The mechanism might be related to the decreased content of DA and Glu and increased content of GABA in the mesolimbic dopamine system.This suggests that PG might be useful for the prevention and treatment of alcohol addiction. | Jia Lingyan Li Yibei Hu Xiaoyu Lin Wu Wen Dachao Zhong Sen | 2016 | Journal of Traditional Chinese Medicine2016，36，2： | 1 |
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