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| 1 | Hydrothermal ore deposits in collisional orogens显示文摘Hydrothermal ore deposits at convergent plate boundaries represent extraordinary metal enrichment in the continental crust. They are generally associated with felsic magmatism in extensional settings at high thermal gradients. Although their formation is common during accretionary orogeny, more and more ore deposits have been discovered recently in the collisional orogens of China. Because collisional orogeny was operated in a compressional regime at low thermal gradients, it is not favorable for mobilization of ore-forming elements and thus for the production of hydrothermal ore deposits. Nevertheless, continental collision is generally preceded by oceanic subduction, which enables the preliminary enrichment of ore-forming elements in the mantle wedge due to chemical metasomatism by subducting slab-derived fluids. This gave rise to metal pre-enriched domains in the overriding lithosphere, which may be reactivated by extensional tectonism for hydrothermal mineralization either immediately during accretionary orogeny or at a later time during and after collisional orogeny. It is these tectonic processes that have resulted in the progressive enrichment of ore-forming elements through the geochemical differentiation of the subducting oceanic crust, the metasomatic mantle domains and the mafic juvenile crust, respectively, at different depths. Finally, the reactivation of metal pre-enriched domains by continental rifting in the orogenic lithosphere is the key to the metallogenesis of collisional orogens. | Yongfei Zheng Jingwen Mao Yanjing Chen Weidong Sun Pei Ni Xiaoyong Yang | 2019 | Science Bulletin2019，64，3： | 26 |
| 2 | Energy optimal routing for long chain-type wireless sensor networks in underground mines显示文摘无线传感器网络是到存在在地下的矿监视系统的有用补充。他们起监视系统的安全提高和改善范围和灵活性的一个重要作用。对在在地下的矿的灾难以后的危险和环境敏感的区域要求节点的节省并且平衡的精力消费延长网络的 lifespan。基于一条隧道的结构,我们在场一个长链类型无线传感器网络(LC-WSN ) 掘监视地下的矿的安全。我们定义最佳的传播距离和关键区域和礼品的范围为 LC-WSN 到的一个精力最佳的路由(EOR ) 算法平衡节点的精力消费并且最大化网络的 lifespan。EOR 基于最佳的传播距离构造路由路径并且使用在关键区域平衡策略的一个精力。模拟结果证明 EOR 算法扩大一个网络的 lifespan,在关键区域平衡节点的精力消费并且有效地限制路由路径的长度,与类似的算法相比。 | Jiang Haifeng Qian Jiansheng Sun Yanjing Zhang Guoyong | 2011 | Mining Science and Technology2011，21，1： | 12 |
| 3 | Geochemistry and Genesis of the Late Jurassic Granitoids at Northern Great Hinggan Range:Implications for Exploration显示文摘迟了的侏罗记的 Longgouhe 和 Ershiyizhan 侵入,在北大 Hinggan 范围的上面的 Heilongjiang 盆定位了,仔细与斑岩 Cu-Au 矿化作用有关。在岩性学,侵入是石英闪长岩,石英 monzodiorite 和 high-K 的 granodiorite 计算碱的系列,与 shoshonite 的次要的方面系列。他们的 SiO2 和 Al2O3 内容分别地从 61.37% ~ 66.59% 和 15.35% ~ 17.06%。MgO 内容从 2.02% ~ 3.47%,与 4459 的 Mg# 索引。(La/Yb ) N 和 Eu/Eu * 价值从 16.85 ~ 81.73 和 0.68 ~ 0.93 分别地,出现的强壮的区别稀土元素元素(REE ) adakites 的类似于那些的模式。岩石在 Ba, Sr 和轻 REE (LREE ) 被充实,显然在 Nb 和 Ta 弄空,稍微弄空在 Rb 和 Ti,和在 Yb 和 Y 的穷人与 0.311.32 ppm 和 4.3212.07 ppm 的 Yb 和 Y 内容,分别地。是由 67.74220.60 的 Sr/Y 比率显示了,岩石被 low-Y 和 high-Sr 内容描绘,它在世界上描绘 adakites。整体地, geochemical tracers 建议感兴趣的侵入是 adakitic 岩石。给 Paleo 亚洲的海洋和蒙古人鄂霍次克海海洋在晚古生代、二叠中间的侏罗记被关上分别地,感兴趣的侵入应该被 delaminated 外壳的部分融化形成,它在 collisional 造山运动在之间期间被变厚西伯利亚并且 Mongolian-Sinokorean 大陆。 | WU Guang CHEN Yanjing SUN Fengyue ZHANG Zhe LIU Ankun LI Zhitong | 2010 | Acta Geologica Sinica(English Edition)2010，84，2： | 10 |
| 4 | An energy efficiency clustering routing protocol for WSNs in confined area显示文摘Wireless sensor networks (WSNs) are important application for safety monitoring in underground coal mines, which are difficult to monitor due to natural conditions. Based on the characteristic of limited energy for WSNs in confined underground area such as coal face and laneway, we presents an energy- efficient clustering routing protocol based on weight (ECRPW) to prolong the lifetime of networks. ECRPW takes into consideration the nodes' residual energy during the election process of cluster heads. The constraint of distance threshold is used to optimize cluster scheme. Furthermore, the protocol also sets up a routing tree based on cluster heads' weight. The results show that ECRPW had better perfor- mance in energy consumption, death ratio of node and network lifetime. | Sun Yanjing He Yanjun Zhang Beibei Liu Xue | 2011 | Mining Science and Technology2011，21，6： | 9 |
| 5 | Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2显示文摘Receptor recognition and subsequent membrane fusion are essential for the establishment of successful infection by SARS-CoV-2.Halting these steps can cure COVID-19.Here we have identified and characterized a potent human monoclonal antibody,HB27,that blocks SARS-CoV-2 attachment to its cellular receptor at sub-nM concentrations.Remarkably,HB27 can also prevent SARS-CoV-2 membrane fusion.Consequently,a single dose of HB27 conferred effective protection against SARS-CoV-2 in two established mouse models.Rhesus macaques showed no obvious adverse events when administrated with10 times the effective dose of HB27.Cryo-EM studies on complex of SARS-CoV-2 trimeric S with HB27 Fab reveal that three Fab fragments work synergistically to occlude SARS-CoV-2 from binding to the ACE2 receptor.Binding of the antibody also restrains any further conformational changes of the receptor binding domain,possibly interfering with progression from the prefusion to the postfusion stage.These results suggest that HB27 is a promising candidate for immuno-therapies against COVID-19. | Ling Zhu Yong-Qiang Deng Rong-Rong Zhang Zhen Cui Chun-Yun Sun Chang-Fa Fan Xiaorui Xing Weijin Huang Qi Chen Na-Na Zhang Qing Ye Tian-Shu Cao Nan Wang Lei Wang Lei Cao Huiyu Wang Desheng Kong Juan Ma Chunxia Luo Yanjing Zhang Jianhui Nie Yao Sun Zhe Lv Neil Shaw Qianqian Li Xiao-Feng Li Junjie Hu Liangzhi Xie Zihe Rao Youchun Wang Xiangxi Wang Cheng-Feng Qin | 2021 | National Science Review2021，8，3： | 3 |
| 6 | Power allocation and mode selection methods for cooperative communication in the rectangular tunnel显示文摘For the multipath fading on electromagnetic waves of wireless communication in the confined areas,the rectangular tunnel cooperative communication system was established based on the multimode channel model and the channel capacity formula derivation was obtained.On the optimal criterion of the channel capacity,the power allocation methods of both amplifying and forwarding(AF) and decoding and forwarding(DF) cooperative communication systems were proposed in the limitation of the total power to maximize the channel capacity.The mode selection methods of single input single output(SISO) and single input multiple output(SIMO) models in the rectangular tunnel,through which the higher channel capacity can be obtained,were put forward as well.The theoretical analysis and simulation comparison show that,channel capacity of the wireless communication system in the rectangular tunnel can be effectively enhanced through the cooperative technology;channel capacity of the rectangular tunnel under complicated conditions is maximized through the proposed power allocation methods,and the optimal cooperative mode of the channel capacity can be chosen according to the cooperative mode selection methods given in the paper. | Zhai Wenyan Sun Yanjing Xu Zhao Li Song | 2015 | International Journal of Mining Science and Technology2015，25，2： | 2 |
| 7 | Precoder Design and Impulsive Noise Mitigation Scheme for Industrial Wireless Communications显示文摘In industrial wireless scenarios,the impulsive noise(IN)incurred by machine running or operation causes a serious influence on the powerlimited industrial wireless communications.It is challenging to ensure efficient and reliable transmission with quality of service(QoS)guarantee for machinetype communication devices(MTCDs).Considering the IN in the industrial process,this paper establishes the multiuser multiple-input single-output(MU-MISO)orthogonal frequency division multiplexing(OFDM)system model,which combines transmitter and receiver design.Two precoding schemes are designed to improve communication effectiveness at the transmitter.More specifically,the precoder design scheme which combines semi-definite relaxation(SDR)with difference-of-two-convex-function(D.C.)iterative algorithm,is developed by utilizing the Dinkelbach method to improve the system effectiveness.To decrease the computational complexity,we devise the quadratic-based fractional programming(QFP)algorithm,which decouples the variables by using a quadratic transform method.On this basis,the IN mitigation scheme is studied to reduce the system error rate(SER)at the receiver.With the goal of improving the reliability of industrial wireless communications,we propose a hybrid nonlinear IN mitigation(HNINM)scheme and then derive its closed-form expression of SER.The simulation results show that the proposed QFP algorithm achieves superior performance while the HNINM scheme decreases the SER of industrial wireless communications. | Yanjing Sun Xinyan Li Jiasi Zhou Ruirui Chen BowenWang Yanfen Wang | 2021 | China Communications2021，18，4： | 1 |
| 8 | Determining the geographic origin of wheat using multielement analysis and multivariate statistics显示文摘 | Zhao H Guo B Wei Y Zhang B Sun S Zhang L YanJ | 2011 | Journal of Agricultural and Food Chemistry2011，59，9： | 1 |
| 9 | Re-Os and U-Pb geochronology of porphyry Mo deposits in central Jilin province : Mo ore-forming stages in NE China显示文摘 | Zhang Yong Sun Jinggui Chen Yanjing | 2013 | International Geology Review2013，55，14： | 1 |
| 10 | Calcium ameliorates obesity induced by high-fat diet and its potential correlation with p38 MAPK pathway显示文摘 | Sun C Wang L YanJ Liu S | 2012 | Mol Biol Rep2012，39，2： | 1 |
| 11 | A spike-trimer protein-based tetravalent COVID-19 vaccine elicits enhanced breadth of neutralization against SARS-CoV-2 Omicron subvariants and other variants显示文摘Multivalent vaccines combining crucial mutations from phylogenetically divergent variants could be an effective approach to defend against existing and future SARS-Co V-2 variants.In this study,we developed a tetravalent COVID-19 vaccine SCTV01E,based on the trimeric Spike protein of SARS-Co V-2 variants Alpha,Beta,Delta,and Omicron BA.1,with a squalenebased oil-in-water adjuvant SCT-VA02B.In the immunogenicity studies in na?ve BALB/c and C57BL/6J mice,SCTV01E exhibited the most favorable immunogenic characteristics to induce balanced and broad-spectrum neutralizing potencies against pre-Omicron variants(D614G,Alpha,Beta,and Delta)and newly emerging Omicron subvariants(BA.1,BA.1.1,BA.2,BA.3,and BA.4/5).Booster studies in C57BL/6J mice previously immunized with D614G monovalent vaccine demonstrated superior neutralizing capacities of SCTV01E against Omicron subvariants,compared with the D614G booster regimen.Furthermore,SCTV01E vaccination elicited na?ve and central memory T cell responses to SARS-Co V-2 ancestral strain and Omicron spike peptides.Together,our comprehensive immunogenicity evaluation results indicate that SCTV01E could become an important COVID-19 vaccine platform to combat surging infections caused by the highly immune evasive BA.4/5 variants.SCTV01E is currently being studied in a head-to-head immunogenicity comparison phase 3 clinical study with inactivated and m RNA vaccines(NCT05323461). | Rui Wang Hongpeng Huang Chulin Yu Chunyun Sun Juan Ma Desheng Kong Yalong Lin Dandan Zhao Shaozheng Zhou Jianbo Lu Sai Cao Yanjing Zhang Chunxia Luo Xuefeng Li Yang Wang Liangzhi Xie | 2023 | Science China(Life Sciences)2023，66，8： | 1 |
| 12 | Investigation on Synthesis of Sintered Mullite from Low-medium Grade Kyanite显示文摘Sintered mullite is prepared by kyanite powder with Al_2O_3 content of 45% and 50%(Yinshan, Nanyang City, China),and the industrial alumina is added to control the chemical composition. The different series of sintered mullite according to the Al_2O_3 content(45%-70%) are designed. The raw materials are mixed and compacted, and then sintered at different temperatures. Physical properties, phase composition, microstructure and refractoriness under load of the synthesized samples are characterized by physical property test, XRD, SEM and RUL test, in order to confirm the quality of sintering and the relationship between temperature and mullitization reaction. The results show that the sintered mullite from low-medium grade kyanite has well developed mullite crystals and a continuous staggered network structure is formed, which has a significant contribution to increasing the high temperature performance of mullite. | YE Hang SUN Gaoyang ZHANG Haibo LI Yanjing GAO Changhe LI Yong YE Fangbao | 2019 | China's Refractories2019，28，1： | 1 |
| 13 | Microglia are involved in pruritus induced by DNFB via the CX3CR1/p38 MAPK pathway 显示文摘 | Zhang Y YanJ Hu R Sun Y Ma Y Chen Z | 2015 | Cell Physiol Biochem2015，35，： | 1 |
| 14 | An antibody cocktail with broadened mutational resistance and effective protection against SARS-CoV-2显示文摘Neutralizing antibodies have been proven to be highly effective in treating mild and moderate COVID-19 patients,but continuous emergence of SARS-CoV-2 variants poses significant challenges.Antibody cocktail treatments reduce the risk of escape mutants and resistance.In this study,a new cocktail composed of two highly potent neutralizing antibodies(HB27 and H89Y)was developed,whose binding epitope is different from those cocktails that received emergency use authorization.This cocktail showed more potent and balanced neutralizing activities(IC_(50)0.9–11.3 ng mL^(-1))against a broad spectrum of SARS-CoV-2 variants over individual HB27 or H89Y antibodies.Furthermore,the cocktail conferred more effective protection against the SARS-CoV-2 Beta variant in an aged murine model than monotherapy.It was shown to prevent SARS-CoV-2 mutational escape in vitro and effectively neutralize 61 types of pseudoviruses harbouring single amino acid mutation originated from variants and escape strains of Bamlanivimab,Casirivimab and Imdevimab with IC_(50)of 0.6–65 ng mL^(-1).Despite its breadth of variant neutralization,the HB27+H89Y combo and EUA cocktails lost their potencies against Omicron variant.Our results provide important insights that new antibody cocktails covering different epitopes are valuable tools to counter virus mutation and escape,highlighting the need to search for more conserved epitopes to combat Omicron. | Chunyun Sun Hang Chi Fei Yuan Jing Li Ji Yang Aihua Zheng Fei Wang Lingling Sun Yanjing Zhang Ping Hu Lihua Jiao Yongqiang Deng Liangzhi Xie | 2023 | Science China(Life Sciences)2023，66，1： | 0 |
| 15 | Effects of proton pump inhibitor on gastroesophageal varices in patients with cirrhosis:A randomized controlled trial from China显示文摘Aims:Proton pump inhibitors(PPI)are widely used for gastroesophageal varices in patients with cirrhosis after endoscopic therapy,although the effect of PPI on these patients remains controversial.This study aimed to evaluate the effect of PPI on gastroesophageal varices in patients with cirrhosis after endoscopic therapy,including variceal bleeding and adverse events.Methods:Cirrhotic patients with endoscopically confirmed gastroesophageal varices were enrolled in this study between May 2017 and June 2019.Eligible patients were randomized into two groups:one group received PPI for 14 days and the other group did not receive PPI treatment(n=53 in each group).All patients were followed for 8 weeks.Results:During the follow‐up period,three patients(5.66%)in the PPI group experienced variceal bleeding on days 9,16,and 25 after endoscopic therapy,including two patients with acute bleeding and one with primary prophylaxis.In the non‐PPI group,three patients(5.66%)experienced variceal bleeding on days 7,42,and 56 after endoscopic therapy,including one patient with acute bleeding and two with secondary prophylaxis(p=0.990).The incidence of adverse events was similar between the two groups(37.74%vs.28.30%,p=0.30).Conclusions:PPI did not appear to reduce variceal bleeding and adverse events in patients with cirrhosis after endoscopic therapy. | Xiaoning Chen Tao Zhou Ting Zhou Yueyue Li Xin Sun Baoquan Cheng Ning Zhong Xuefeng Lu Yanjing Gao | 2023 | Portal Hypertension & Cirrhosis2023，2，1： | 0 |
| 16 | Predicting of Covalent Organic Frameworks for Membrane-based Isobutene/1,3-Butadiene Separation:Combining Molecular Simulation and Machine Learning显示文摘Efficient separation of C4 olefins is of critical importance and a challenging task in petrochemical industry. Covalent organic frameworks(COFs) could be used as promising candidates for membrane-based isobutene/1,3-butadiene(i-C4H8/C4H6) separation. Owing to large amounts of COFs appearing, however, the rapid prediction of optimal COFs is imperative before experimental efforts. In this work, we combine molecular simulation and machine learning to study COF membranes for efficient isolation of i-C4H8 over C4H6. Using molecular simulation, four potential COF membranes, which possess both high membrane performance score (MPS) value and moderate membrane selectivity were screened out and the mechanism of membrane separation further revealed is an adsorption dominated process. Further, random forest(RF) model with high prediction accuracy(R2>0.84) was obtained and used for elucidating key factors in controlling the membrane selectivity and i-C4H8 permeability. Ultimately, the optimal COF features were obtained through structure-performance relationship study. Our results may trigger experimental efforts to accelerate the design of novel COFs with better i-C4H8/C4H6separation performance. | CAO Xiaohao HE Yanjing ZHANG Zhengqing SUN Yuxiu HAN Qi GUO Yandong ZHONG Chongli | 2022 | Chemical Research in Chinese Universities2022，38，2： | 0 |
| 17 | Energy-Efficient Data Collection over Underwater MI-Assisted Acoustic Cooperative MIMO WSNs显示文摘Underwater magnetic induction(MI)-assisted acoustic cooperative multiple-input-multipleoutput(MIMO) has been recently proposed as a promising technique for underwater wireless sensor networks(UWSNs).For the more,the energy utilization of energy-constrained sensor nodes is one of the key issues in UWSNs,and it relates to the network lifetime.In this paper,we present an energy-efficient data collection for underwater MI-assisted acoustic cooperative MIMO wireless sensor networks(WSNs),including the formation of cooperative MIMO and relay link establishment.Firstly,the cooperative MIMO is formed by considering its expected transmission range and the energy balance of nodes with it.Particularly,from the perspective of the node’s energy consumption,the expected cooperative MIMO size and the selection of master node(MN) are proposed.Sequentially,to improve the coverage of the networks and prolong the network lifetime,relay links are established by relay selection algorithm that using matching theory.Finally,the simulation results show that the proposed data collection improves its efficiency,reduces the energy consumption of the master node,improves the networks’ coverage,and extends the network lifetime. | Qingyan Ren Yanjing Sun Song Li Bin Wang Zhengda Yu | 2023 | China Communications2023，20，11： | 0 |
| 18 | High-throughput screening and evaluation of repurposed drugs targeting the SARS-CoV-2 main protease显示文摘Dear editor,To date,a number of clinically approved drugs have been evaluated for potential to treat coronavirus disease 2019(COVID-19),such as lopinavir/ritonavir,hydroxychloroquine,cobicistat,and darunavir.Some of these drugs have been proven to be effective in vitro;however,clinical trials showed that none of these compounds led to a significant improvement in symptoms or length of hospitalization.Thus,it is essential and more reliable to start from a defined target to ide ntify can didate drugs. | Yan Li Jinyong Zhang Zilei Duan Ning Wang Xiangcheng Sun Yanjing Zhang Li Fu Kaiyun Liu Yongjun Yang Shulei Pan Yun Shi Hao Zeng Gang Guo Ren Lai Quanming Zou | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 0 |
| 19 | Development, Application and Prospect of Dissolving Microneedles显示文摘In recent years, as a new transdermal drug delivery method, microneedle transdermal drug delivery technology accelerates the absorption of drugs through micron pores, which has been widely used in the field of medicine and cosmetics. Dissolving microneedles have the characteristics of good biocompatibility and fast dissolution speed, which attract more and more researchers’ attention and research. In this paper, the concept, properties and preparation methods of dissolving microneedles as well as the research status of dissolving microneedles in the field of medicine and cosmetics in recent years were summarized and prospected, so as to enable researchers to have a clearer and comprehensive understanding of dissolving microneedles and prospect the application and development prospects of dissolving microneedles in the industry. | Juan YAN Chaoguo SUN Yanjing LI Yuchen CUI Dongfang SHI Suohui ZHANG | 2023 | Agricultural Biotechnology2023，12，1： | 0 |
| 20 | The extraction of aromatics using N-methylpyrrolidone: Liquid-liquidequilibrium determination and mechanism exploration显示文摘LLE data of cyclooctane/3-methylpentane + benzene/toluene + N-methylpyrrolidone (NMP) at 298.15 Kand 313.15 K under a pressure of 101.3 kPa were measured in this work. The Othmer-Tobias and Handequations were adopted to validate the reliability of LLE data, where the correlation coefficients (R2) wereclose to unity, indicating the high reliability of the experimental data. The experimental data were analyzed using the distribution coefficient (D) and separation factor (S), and the effect of NMP extracting benzene and toluene from aromatics was explored. Meanwhile, the reason for the different extractionefficiencies of benzene and toluene using NMP was analyzed by quantum chemical calculations. TheNRTL and UNIQUAC thermodynamic models were used to correlate the liquid–liquid equilibrium data,and the relevant binary interaction parameters were obtained. The calculated root mean square deviation(RMSD) were all less than 0.0063, indicating that the obtained binary interaction parameters can be usedto simulate and calculate the extraction of aromatics using NMP. | Yanjing Li Shilong Dong Lili Wang Xiaoyan Sun Wenying Zhao Shuguang Xiang | 2023 | Chinese Journal of Chemical Engineering2023，64，12： | 0 |
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