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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Changes of free radicals and digestive enzymes in saliva in cases with deficiency inspleen-yin syndrome显示文摘Objective:To explore the nature of deficiency in spleen-yin syndrome,which could provide scientific theoretical support and practical guidance for clinical Traditional Chinese Medicine(TCM)syndrome differentiation based on biology,and had a strong clinical significance.Methods:Serum Cu and Zn were detected by atomic absorption spectrophotometer,serum vitamin E by high performance liquid chromatography,serum vitamin C by 2,4-Dinitrophenylhydrazine Colorimetry,total superoxide dismutase(SOD)and Cu and Zn- SOD by the xanthine oxidase method,and malondialdehyde(MDA)by the 2-thiobarbituric acid method(TBA).Total antioxidant capacity was detected by a colorimetry kit.Amylase Activity was detected by an automatic biochemical analyzer.Lysozyme was detected by lysozyme detection plate,the diameter of bacteriolysis circle was measured and the corresponding content of lysozyme was obtained from a table of standard curve values.Results: No significant difference in total SOD and Cu,Zn-SOD was found between deficiency in spleen-yin group and normal group.However,such factors in deficiency in kidney-yin group were significantly lower than the other groups(P<0.05).The MDA content in both deficiency in spleen-yin group and deficiency in kidney-yin group were significantly higher than that of normal group(P<0.05),while the total antioxidant capacity was significantly lower than normal group(P<0.05).The vitamin E content in deficiency in kidney-yin group was significantly lower than that in the other two groups(P<0.05).No significant difference in the contents of vitamin C,Cu and Zn were observed in these groups.The Zn/Cu level in deficiency in kidney-yin group and the vitamin E level in deficiency in spleen-yin group decreased,but with no significant difference.Amylase activity in unit time in cases with deficiency in spleen-yin was lower than and had significant differences with that in normal cases,and higher than that in cases with deficiency in kidney-yin.The sectional velocity of saliva and the ratio of lysozyme in normal case group were significantly higher than other two groups,while deficiency in the spleen-yin group was significantly higher than the deficiency in kidney-yin group.Conclusion:All the results indicated that the objective pathological mechanism between the deficiency in spleen-yin and deficiency in kidney-yin was different. | Muxin Wei Yanmin Wu Dezheng Chen Yuchun Gu | 2010 | The Journal of Biomedical Research2010，24，3： | 13 |
| 3 | Precise base editing of non-allelic acetolactate synthase genes confers sulfonylurea herbicide resistance in maize显示文摘Single-nucleotide polymorphisms contribute to phenotypic diversity in maize. Creation and functional annotation of point mutations has been limited by the low efficiency of conventional methods based on random mutation. An efficient tool for generating targeted single-base mutations is desirable for both functional genomics and precise genetic improvement. The objective of this study was to test the efficiency of targeted C-to-T base editing of two non-allelic acetolactate synthase(ALS) in generating sulfonylurea herbicide-resistant mutants. A CRISPR/Cas9 nickase-cytidine deaminase fused with uracil DNA glycosylase inhibitor(UGI) was employed to achieve targeted conversion of cytosine to thymine in ZmALS1 and ZmALS2. Both protoplasts and recovered mutant plants showed the activity of the cytosine base editor, with an in vivo efficiency of up to 13.8%. Transgene-free edited plants harboring a homozygous ZmALS1 mutation or a ZmALS1 and ZmALS2 double mutation were tested for their resistance at a dose of up to 15-fold the recommended limit of chlorsulfuron, a sulfonylurea herbicide widely used in agriculture. Targeted base editing of C-to-T per se and a phenotype verified in the generated mutants demonstrates the power of base editing in precise maize breeding. | Yanmin Li Jinjie Zhu Hao Wu Changlin Liu Changling Huang Jinhao Lan Yanming Zhao Chuanxiao Xie | 2020 | The Crop Journal2020，8，3： | 9 |
| 4 | Enhanced pyrocatalysis of the pyroelectric BiFeO_(3)/g-C_(3)N_(4) heterostructure for dye decomposition driven by cold–hot temperature alternation显示文摘The BiFeO_(3)/g-C_(3)N_(4) heterostructure,which is fabricated via a simple mixing–calcining method,benefits the significant enhancement of the pyrocatalytic performance.With the growth of g-C_(3)N_(4) content in the heterostructure pyrocatalysts from 0 to 25%,the decomposition ratio of Rhodamine B(RhB)dye after 18 cold-hot temperature fluctuation(25-65℃)cycles increases at first and then decreases,reaching a maximum value of~94.2%at 10%while that of the pure BiFeO_(3) is~67.7%.The enhanced dye decomposition may be due to the generation of the internal electric field which strengthens the separation of the positive and negative carriers and further accelerates their migrations.The intermediate products in the pyrocatalytic reaction also have been detected and confirmed,which proves the key role of the pyroelectric effect in realizing the dye decomposition using BiFeO_(3)/g-C_(3)N_(4) heterostructure catalyst.The pyroelectric BiFeO_(3)/g-C_(3)N_(4) heterostructure shows the potential application in pyrocatalytically degrading dye wastewater. | Mingzi Chen Yanmin Jia Huamei Li Zheng Wu Tianyin Huang Hongfang Zhang | 2021 | Journal of Advanced Ceramics2021，10，2： | 6 |
| 5 | Effectiveness of Catch-Up Vaccinations after COVID-19 Containment--China,2020显示文摘Introduction:In the early stages of the coronavirus disease 2019(COVID-19)epidemic in China,the highest level of public health emergency response(Level 1 Response)was launched in all province-level administrative divisions(PLADs)across the country.Provision of vaccination services was selectively suspended due to the physical distancing and gathering restrictions required of Level 1 Response.The purpose of this paper is to evaluate the impact of COVID-19 on vaccination services and the effectiveness of selective vaccination service suspension and catch-up vaccinations in China.Methods:Vaccine doses administered,routine vaccination coverage levels,catch-up vaccine doses administered,and coverage levels after the catch-up campaign were determined from individual vaccination records in sampled clinics,standard routine immunization administrative coverage reports,and catch-up vaccination activity reports submitted by PLADs between October 2019 and October 2020.Results:National Immunization Program(NIP)and non-NIP vaccine doses administered in sampled clinics decreased by 80% and 90%,respectively,compared with doses administered before the COVID-19 pandemic.Coverage with the birth dose of hepatitis B vaccine(HepB1)and the Bacillus Calmette-Guérin vaccine(BCG)—two vaccinations recommended to continue throughout the epidemic due to their timecritical nature—were maintained at over 85%,while coverage of other NIP vaccines decreased to below 60%by February 2020.Catch-up vaccination coverage of the 29 PLADs,excluding Xinjiang and Xizang(Tibet),began in April 2020 and exceeded 90%;Hubei catch-up coverage was 95% by October 2020.Conclusions and Implications for Public Health Practice:The COVID-19 pandemic had a great impact on China’s vaccination services.During the epidemic and time of local transmission of the coronavirus,HepB1,BCG,rabies vaccine for postexposure prophylaxis,and tetanus antitoxin(TAT)for wound prophylaxis were maintained at high levels.Of the 69 million vaccine doses postponed during the time of local transmission of the coronavirus,94% were administered in the catch-up campaign.China’s pandemic immunization practices may provide evidence for other countries’immunization programs. | Jing Wu Wenzhou Yu Lei Cao Lingsheng Cao Lance Rodewald Jiakai Ye Yifan Song Li Li Xiaoxue Liu Ning Wen Fuzhen Wang Lixin Hao Yixing Li Hui Zheng Keli Li Chao Ma Dan Wu Yanmin Liu Guomin Zhang Zhijie An Huaqing Wang Zundong Yin | 2020 | China CDC weekly2020，2，50： | 6 |
| 6 | Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis:a prospective multicenter randomized controlled trial显示文摘Objective:Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding.The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation(RCA)combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis(IHD)treatment.Methods:Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments,and were randomly divided into RCA group and saline flushing group.In the RCA group,0.04 g/mL sodium citrate was infused from the start of the dialysis line during blood draining and at the venous expansion chamber.The sodium citrate was stopped after 3 h of dialysis,which was changed to sequential dialysis without anticoagulant.The hazard ratios for coagulation were according to baseline.Results:A total of 159 patients and 208 sessions were enrolled,including RCA group(80 patients,110 sessions)and saline flushing group(79 patients,98 sessions).The incidence of severe coagulation events of extracorporeal circulation in the RCA group was significantly lower than that in the saline flushing group(3.64%vs.20.41%,P<0.001).The survival time of the filter pipeline in the RCA group was significantly longer than that in the saline flushing group((238.34±9.33)min vs.(221.73±34.10)min,P<0.001).The urea clearance index(Kt/V)in the RCA group was similar to that in the saline flushing group with no statistically significant difference(1.12±0.34 vs.1.08±0.34,P=0.41).Conclusions:Compared with saline flushing,the two-stage RCA combined with a sequential anticoagulation strategy significantly reduced extracorporeal circulation clotting events and prolonged the dialysis time without serious adverse events. | Xiaoyan TANG Dezheng CHEN Ling ZHANG Ping FU Yanxia CHEN Zhou XIAO Xiangcheng XIAO Weisheng PENG Li CHENG Yanmin ZHANG Hongbo LI Kehui LI Bizhen GOU Xin WU Qian YU Lijun JIAN Zaizhi ZHU Yu WEN Cheng LIU Hen XUE Hongyu ZHANG Xin HE Bin YAN Liping ZHONG Bin HUANG Mingying MAO | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，11： | 4 |
| 7 | The susceptibility of T5-TG12 of theCFTR gene in chronic bronchitis occurrence in a Chinese population in Jiangsu province,China显示文摘Mutations in the cystic fibrosis transmembrane conductance regulator(CFTR) gene have been implicated in the onset of cystic fibrosis and other clinical respiratory disorders.In the present study,we investigated the role of CFTR variations,poly-T,TG-repeats,and M470V in susceptibility to bronchial asthma and chronic bronchitis in a Chinese population in Jiangsu province,China.A total of 72 bronchial asthma patients,68 chronic bronchitis patients,and 117 healthy subjects were included in this study.The Tn-TGm haplotype was sequenced and the CFTR variant M470V was detected using restriction fragment length polymorphism(RFLP).We found that the frequency of T5-TG12-V470 in chronic bronchitis patients was 0.07%,which was notably higher than that in healthy subjects(0.01%) and bronchial asthma patients(0.04%).Thus,the presence of the T5-TG12 haplotype of the CFTR gene is likely to play a role in the development and progression of respiratory conditions,such as chronic bronchitis. | Ping Wang Satoru Naruse Hong Yin Zhongfang Yu Tianqu Zhuang Wei Ding Yanmin Wu Muxin Wei | 2012 | The Journal of Biomedical Research2012，26，6： | 4 |
| 8 | Tuning filament composition and microstructure of 3D-printed bioceramic scaffolds facilitate bone defect regeneration and repair显示文摘It is still a challenge to optimize the component distribution and microporous structures in scaffolds for tailoring biodegradation(ion releasing)and enhancing bone defect repair within an expected time stage.Herein,the core–shell-typed nonstoichiometric wollastonite(4%and 10%Mg-doping calcium silicate;CSiMg4,CSiMg10)macroporous scaffolds with microporous shells(adding~μ10 μm PS microspheres into shell-layer slurry)were fabricated via 3D printing.The initial mechanical properties and bio-dissolution(ion releasing)in vitro,and osteogenic capacity in vivo of the bioceramic scaffolds were evaluated systematically.It was shown that endowing high-density micropores in the sparingly dissolvable CSiMg10 or dissolvable CSiMg4 shell layer inevitably led to nearly 30%reduction of compressive strength,but such micropores could readily tune the ion release behaviour of the scaffolds(CSiMg4@CSiMg10 vs.CSiMg4@CSiMg10-p;CSiMg10@CSiMg4 vs.CSiMg10@CSiMg4-p).Based on the in rabbit femoral bone defect repair model,the 3D μCT reconstruction and histological observation demonstrated that the CSiMg4@CSiMg10-p scaffolds displayed markedly higher osteogenic capability than the other scaffolds after 12weeks of implantation.It demonstrated that core–shell bioceramic 3D printing technique can be developed to fabricate single-phase or biphasic bioactive ceramic scaffolds with accurately tailored filament biodegradation for promoting bone defect regeneration and repair in some specific pathological conditions. | Yi Chen Jiaping Huang Jiamei Liu Yingming Wei Xianyan Yang Lihong Lei Lili Chen Yanmin Wu Zhongru Gou | 2021 | Regenerative Biomaterials2021，8，2： | 3 |
| 9 | Does Hepatic Ischemia–Reperfusion Injury Induced by Hepatic Pedicle Clamping Affect Survival after Partial Hepatectomy for Hepatocellular Carcinoma?显示文摘 | Feng Xia Wan-Yee Lau Yanmin Xu Lin Wu Cheng Qian Ping Bie | 2013 | World Journal of Surgery2013，，1： | 2 |
| 10 | Lightweight Design of Spaceborne CFRP Rigid Antenna Reflector显示文摘In order to overcome the shortcoming of space-borne rigid antenna reflector made of carbon fiber reinforced plastic(CFRP)skins with aluminum honeycomb sandwich(SAHS)structure,a new type of full CFRP skin plus rib(SPR)structure ring-focused parabolic surface antenna reflector with the size of 2.5 m×1.9 m is designed.Under the condition that the original caliber,surface type,and interface remain unchanged,the main influence factors are designed and controlled.First,from the perspective of high stiffness,lightweight,and easy to form,a finite element simulation software is used to analyze and optimize the layout of the rib,the cross-sectional shape of the rib,the size of the rib,and the matching of the size and the coefficients of thermal expansion(CTEs)of the rib and the skin.Second,two structures are prepared by the autoclave molding process.Third,the weight and the surface precision root mean square(RMS)value are measured.The results show that the fundamental frequency of the SPR structure is 142.2 Hz,which is 3.5 Hz higher;the number of the new structural parts is reduced by 40%,and the forming process is greatly simplified.The total weight of the new structure is 11.9 kg,lighter 42.5%,indicating that the weight loss is obvious.The RMS value is 0.15 mm,which is slightly lower 0.01 mm but satisfies the accuracy requirement not greater than 0.3 mm.It is proved that the SPR structure reflector is a superior structure of the lightweight spaceborne antenna reflector. | ZHOU Tao LIANG Yanmin WU Wenping WU Xinrui YE Zhoujun DONG Bin | 2022 | 上海航天(中英文)2022，39，1： | 1 |
| 11 | Fabrication and In vitro Bioactivity of Robust Hydroxyapatite Coating on Porous Titanium Implant显示文摘Compared witli the traditional dental implant, TixOs■ manufactured by direct laser metal forming(DLMF) technology exhibits improved capability for bone osteointegration due to its porous surface structure, and has achieved remarkable clinical effect. However, like the traditional titanium and other alloyed implants, the porous titanium implant TixOsR also has relatively weak bioactivity. To address this issue, a proper surface modification method may be needed. Hydroxyapatite(HA) has been widely used in implant surface coating for its similar chemical composition to bone tissue and its osteoconductive properties. Thus, combining TixOs■ implants with hydroxyapatite can be an efficient way to enhance their bioactivity. We herewith reported a competent pulsed laser deposition(PLD) method of coating nano-sized HA thin film onto the porous TixOs■ implant. The HA coatings were characterized by means of scanning electron microscopy(SEM), energy dispersive X-ray spectroscopy(EDS), X-ray photoelectron spectroscopy(XPS) and focused ion beam(FIB) method, and nanocrystal sized thin HA films were identified on the surface of TixOs■ implants. The low cytotoxicity and improved cell proliferation ability of HA coated implants were further tested and verified using MC 3T3 E1 cells with the consideration of the controlling group. Our results show that a stable and bioactive HA tliin film is able to form on the surtace of the porous titanium implant by PLD method.This may benefit the fiirther clinical application of TixOs■ implants. | DUAN Mengna WU Xiaofeng YUAN Long ZHANG Zhiying ZHANG Yan ZHOU Yanmin | 2019 | Chemical Research in Chinese Universities2019，35，4： | 1 |
| 12 | Study on Sampling Technique of Atmospheric Radionuclide显示文摘Atmospheric radionuclide monitoring usually includes two sampling techniques,namely ultra-high volume aerosol samplers to collect atmospheric particles by using filter media,and radioactive noble gas samplers to collect atmospheric noble gas based on adsorption method. Atmospheric sampling techniques have been researched in Northwest Institute of Nuclear Technology since the Comprehensive Nuclear-Test-Ban Treaty( CTBT) was signed in 1996. Several ultra-high volume aerosol samplers and some types of radioactive xenon isotopes samplers had been developed. For the aerosol sampler,the sampling flow is between 450 and 800 m3/h,with the minimum detectable concentration( MDC) of131 I less than5 μBq /m3. For the xenon sampler,the sampling capacity of xenon is more than 4 ml per day,with MDC of133 Xe less than 0. 25 mBq /m3. After the nuclear accident of Fukushima in 2011,monitoring of the atmospheric radionuclide was carried out for 3 months at Xi'an,and part of radionuclide was detected with concentrations higher than their backgrounds in the period,including131 I,134Cs,137 Cs and133Xe. | Wu Shan Liu Longbo Zhang Changyun Tang Hanbing Chen Liyun Wu Yanmin Xie Feng Li Zhiming Shi Quanlin Dang Haijun | 2014 | Meteorological and Environmental Research2014，5，6： | 1 |
| 13 | Optimization of enzymatic pretreatment for n -hexane extraction of oil from Silybum marianum seeds using response surface methodology显示文摘 | Fang Li Liuqing Yang Ting Zhao Jiangli Zhao Yanmin Zou Ye Zou Xiangyang Wu | 2011 | Food and Bioproducts Processing2011，，2： | 1 |
| 14 | Structural characterization and antioxidant activities activities of κ-carrageenan oligosaccharides degraded by different methods显示文摘 | SUN Yujiao YANG Bingying WU Yanmin | 2015 | Food Chemistry2015，178，1： | 1 |
| 15 | MATLAB RTW Tool Application to Configure RBF Neural Network PID Con- troller of Turntable Servo System 显示文摘 | Yanmin Wu Chun Huang Wei Deng | 2012 | International Review on Computers and Software2012，7，5： | 1 |
| 16 | Effects of Low Temperature on Properties of Structural Steel显示文摘 | Wu Yanmin Wang Yuanqing Shi Yongjiu | 2004 | Journal of University of Science and Technology2004，11，5： | 1 |
| 17 | MATLAB RTW Tool Application to Configure RBF Neural Network PID Controller of Turntable Servo System 显示文摘 | Yanmin Wu Chun Huang Wei Deng | 2012 | International Review on Computers and Software2012，7，5： | 1 |
| 18 | Vaccination Guidelines During and After the COVID-19 Epidemic in China显示文摘In late December 2019,clinicians in Hubei Province noticed and reported to health authorities a cluster of cases of pneumonia of unknown etiology(PUE)that turned out to be the start of the coronavirus disease 2019(COVID-19)pandemic(1).By January 29,2020,all provincial-level administrative divisions(PLADs)across the country had launched their highest public health emergency responses(Level 1 responses)(2-3). | Wenzhou Yu Yuanqiu Li Jing Wu Fuzhen Wang Ning Wen Lance Rodewald Lixin Hao Yixing Li Hui Zheng Keli Li Chao Ma Dan Wu Lei Cao Lingsheng Cao Jiakai Ye Yanmin Liu Guomin Zhang Wen Du Zhijie An Huaqing Wang Zundong Yin | 2020 | China CDC weekly2020，2，34： | 1 |
| 19 | Oxygen-vacancy-related high-temperature dielectric relaxation and electrical conduction in 0.95K 0.5 Na 0.5 NbO 3 –0.05BaZrO 3 ceramic显示文摘 | Laijun Liu Yanmin Huang Yunhua Li Meixie Wu Liang Fang Changzheng Hu Yanzhong Wang | 2011 | Physica B: Physics of Condensed Matter2011，，1： | 1 |
| 20 | Piezoelectric bimorph cantilever for vibration-producing-hydrogen 显示文摘 | Zhang Jun Wu Zheng Jia Yanmin | 2013 | Sensors2013，13，1： | 1 |
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