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| 1 | Efficient adiabatic silicon-on-insulator waveguide taper显示文摘A silicon-on-insulator-based adiabatic waveguide taper with a high coupling efficiency and small footprint is presented.The taper was designed to reduce the incidence of mode conversion to higher-order and radiation modes inside the waveguide.In connecting a 0.5-μm-wide output waveguide and a 12-μm-wide input waveguide of a grating coupler,a compact 120-μm-long taper was demonstrated,achieving a transmission of 98.3%.Previously,this transmission level could only be achieved using a conventional linear taper with a length of more than 300μm. | Yunfei Fu Tong Ye Weijie Tang Tao Chu | 2014 | Photonics Research2014，2，3： | 10 |
| 2 | Classifying rheumatoid arthritis by Traditional Chinese Medicine Zheng: a multi-center cross-sectional study显示文摘OBJECTIVE:To assess the relationship between disease symptoms and traditional Chinese medicine (TCM) syndrome (Zheng) in rheumatoid arthritis (RA) patients.METHODS:RA Patients were recruited in Guang'anmen Hospital,China Academy of Chinese Medical Sciences and in the Second Affiliated Hospital of Zhejiang Chinese Medical University,and diagnosed with a particular RA Zheng from their symptoms.Demographic characteristics,self-reported symptoms,and blood samples were collected from patients.All data were input into EpiData and analyzed using SPSS software.RESULTS:The study included 302 RA patients (age range:18-86 years).All patients were Chinese,and 85.1% were women.Cold and fatigue triggers were reported by 8.6% of patients,followed by triggers such as childbirth (4.3%),cold (3.0%),dampness (2.0%),menopause (1.3%),and psychentonia (0.7%).The most prevalent Zheng was dampness and heat blockage (Shire Yuzu in Chinese,SRYZ),diagnosed in 39.4% of patients (119),followed by phlegm and stagnation blockage (Tanyu Bizu,TYBZ) in 21.5%,liver and kidney deficiency (Ganshen Buzu,GSBZ) in 18.5%,dual deficiency of Qi and blood (Qixue Liangxu,QXLX) in 9.6%,cold and dampness blockage (Hanshi Bizu,HSBZ) in 6%,and wind and dampness blockage (Fengshi Bizu,FSBZ) in 5%.Increased length of time since RA diagnosis was associated with the GSBZ group.Patients diagnosed with the SRYZ Zheng had the highest disease activity score.Patients diagnosed with the QXLX Zheng had the lowest blood platelet counts;patients diagnosed with the QXLX and HSBZ Zhengs had lower C-reactive protein levels and lower health assessment questionnaire scores.Patients diagnosed with the GSBZ and QXLX Zhengs had the highest health assessment questionnaire scores.CONCLUSION:The specific Zheng was related to RA characteristics.The findings suggest that eliminating dampness,cooling the patient,and promoting blood circulation may assist in treating severe RA. | Wang Weijie Tang Xiaopo Wang Xinchang Jiang Quan Fan Yongsheng | 2019 | Journal of Traditional Chinese Medicine2019，39，3： | 7 |
| 3 | Challenges and strategies in high-accuracy manufacturing of the world’s largest SiC aspheric mirror显示文摘In the process of manufacturing the world’s largest silicon carbide(SiC)aspheric mirror,the primary difficulties are mirror blank preparation,asphere fabrication,and testing,as well as cladding and coating.Specifically,the challenges include the homogeneity of the complicated structure casting,accuracy and efficiency of the fabrication process,print-through effect,fidelity and precision of test procedure,stress and denseness of cladding process,the dynamic range of interferometric measurement,and air turbulence error due to the long optical path.To break through such a barrier of difficulties,we proposed the water-soluble room temperature vanishing mold and gel casting technology,homogeneous microstructure reaction-formed joint technology,nano-accuracy efficient compound fabrication,gravity unloading technology,high-denseness low-defect physical vapor deposition(PVD)Si-cladding technology,test data fusion method,and time-domain averaging method,etc.Based on the proposed technologies and methods,we have accomplished the world’s largest SiC aspheric mirror with a size of φ4.03 m.The impressive performance of the SiC aspheric mirror is validated by the characteristics of the fabricated SiC aspheric mirror.The aerial density of the SiC blank is less than 120 kg/m^(2),surface shape test accuracy is better than 6 nm RMS,thickness inhomogeneity of the cladding layer is less than 5%,and the final surface figure error and roughness are 15.2 nm RMS and 0.8 nm RMS,respectively. | Xuejun Zhang Haixiang Hu Xiaokun Wang Xiao Luo Ge Zhang Wenxing Zhao Xiaoyi Wang Zhenyu Liu Ling Xiong Erhui Qi Congcong Cui Yanchao Wang Yingjie Li Xu Wang Longxiang Li Yang Bai Qiang Cheng Zhiyu Zhang Ruigang Li Wa Tang Xuefeng Zeng Weijie Deng Feng Zhang | 2022 | Light(Science & Applications)2022，11，12： | 3 |
| 4 | Comprehensive Proteomic Profiling of Patients'Tears Identifies Potential Biomarkers for the Traumatic Vegetative State显示文摘The vegetative state is a complex condition with unclear mechanisms and limited diagnostic, prognostic,and therapeutic methods. In this study, we aimed to explore the proteomic profile of tears from patients in a traumatic vegetative state and identify potential diagnostic markers using tears—a body fluid that can be collected noninvasively. Using i TRAQ quantitative proteomic technology, in the discovery phase, tear samples collected from 16 patients in a traumatic vegetative state and 16 normal individuals were analyzed. Among 1080 identified tear proteins, 57 were upregulated and 15 were downregulated in the patients compared to the controls. Bioinformatics analysis revealed that the differentially-expressed proteins were mainly involved in the wound response and immune response signaling pathways. Furthermore, we verified the levels of 7 differentially-expressed proteins in tears from50 traumatic vegetative state patients and 50 normal controls(including the samples used in the discovery phase) using ELISA. The results showed that this 7-protein panel had a high discrimination ability for traumatic vegetative state(area under the curve = 0.999). In summary, the altered tear proteomic profile identified in this study provides a basis for potential tear protein markers for diagnosis and prognosis of the traumatic vegetative state and also provides novel insights into the mechanisms of traumatic vegetative state. | Qilin Tang Chao Zhang Xiang Wu Wenbin Duan Weiji Weng Junfeng Feng Qing Mao Shubin Chen Jiyao Jiang Guoyi Gao | 2018 | Neuroscience Bulletin2018，34，4： | 3 |
| 5 | miR-17-5p as a Novel Prognostic Marker for Hepatocellular Carcinoma显示文摘 | Ling Chen Meng Jiang Weijie Yuan Huihuan Tang | 2012 | Journal of Investigative Surgery2012，，3： | 3 |
| 6 | Quantitation of HBV covalently closed circular DNA in micro formalin fixed paraffin-embedded liver tissue using rolling circle amplification in combination with real-time PCR显示文摘 | Yanwei Zhong Jiaqi Han Zhengsheng Zou Shuhong Liu Bo Tang Xiaoqiang Ren Xiaodong Li Yulai Zhao Yan Liu Dongqing Zhou Weijie Li Jingmin Zhao Dongping Xu | 2011 | Clinica Chimica Acta2011，，21： | 2 |
| 7 | Estimation of spectral responses and chlorophyll based on growth stage effects explored by machine learning methods显示文摘Estimation of leaf chlorophyll content(LCC) by proximal sensing is an important tool for photosynthesis evaluation in high-throughput phenotyping. The temporal variability of crop biochemical properties and canopy structure across different growth stages has great impacts on wheat LCC estimation, known as growth stage effects. It will result in the heterogeneity of crop canopy at different growth stages, which would mask subtle spectral response of biochemistry variations. This study aims to explore spectral responses on the growth stage effects and establish LCC models suited for different growth stages. A total number of 864 pairwise samples of wheat canopy spectra and LCC values with 216 observations of each stage were sampled at the tillering, jointing, booting and heading stages in 2021. Firstly, statistical analysis of LCC and spectral response presented different distribution traits and typical spectral variations peak at 470, 520 and 680 nm. Correlation analysis between LCC and reflectance showed typical red edge shifts. Secondly, the testing model of partial least square(PLS) established by the entire datasets to validate the predictive performance at each stage yielded poor LCC estimation accuracy. The spectral wavelengths of red edge(RE) and blue edge(BE) shifts and the poor estimation capability motivated us to further explore the growth stage effects by establishing LCC models at respective growth periods.Finally, competitive adaptive reweighted sampling PLS(CARS-PLS), decision tree(DT) and random forest(RF) were used to select sensitive bands and establish LCC models at specific stages. Bayes optimisation was used to tune the hyperparameters of DT and RF regression. The modelling results indicated that CARS-PLS and DT did not extract specific wavelengths that could decrease the influences of growth stage effects. From the RF out-of-bag(OOB) evaluation, the sensitive wavelengths displayed consistent spectral shifts from BE to GP and from RE to RV from tillering to heading stages. Compared with CARS-PLS and DT,results of RF modelling yielded an estimation accuracy with deviation to performance(RPD) of 2.11, 2.02,3.21 and 3.02, which can accommodate the growth stage effects. Thus, this study explores spectral response on growth stage effects and provides models for chlorophyll content estimation to satisfy the requirement of high-throughput phenotyping. | Dehua Gao Lang Qiao Lulu An Ruomei Zhao Hong Sun Minzan Li Weijie Tang Nan Wang | 2022 | The Crop Journal2022，10，5： | 2 |
| 8 | Transport Patterns and Potential Sources of Atmospheric Pollution during the ⅩⅩⅣ Olympic Winter Games Period显示文摘The attainment of suitable ambient air quality standards is a matter of great concern for successfully hosting the ⅩⅩⅣ Olympic Winter Games(OWG). Transport patterns and potential sources of pollutants in Zhangjiakou(ZJK) were investigated using pollutant monitoring datasets and a dispersion model. The PM_(2.5) concentration during February in ZJK has increased slightly(28%) from 2018 to 2021, mostly owing to the shift of main potential source regions of west-central Inner Mongolia and Mongolian areas(2015–18) to the North China Plain and northern Shanxi Province(NCPS) after 2018.Using CO as an indicator, the relative contributions of the different regions to the receptor site(ZJK) were evaluated based on the source-receptor-relationship method(SRR) and an emission inventory. We found that the relative contribution of pollutants from NCPS increased from 33% to 68% during 2019–21. Central Inner Mongolia(CIM) also has an important impact on ZJK under unfavorable weather conditions. This study demonstrated that the effect of pollution control measures in the NCPS and CIM should be strengthened to ensure that the air quality meets the standard during the ⅩⅩⅣ OWG. | Yuting ZHANG Xiaole PAN Yu TIAN Hang LIU Xueshun CHEN Baozhu GE Zhe WANG Xiao TANG Shandong LEI Weijie YAO Yuanzhe REN Yongli TIAN Jie LI Pingqing FU Jinyuan XIN Yele SUN Junji CAO Zifa WANG | 2022 | Advances in Atmospheric Sciences2022，39，10： | 1 |
| 9 | Efficient catalytic oxidation of HCl to recycle Cl2 over the CuO-CeO2 composite oxide supported on Y type zeolite 显示文摘 | Fei Zhaoyang Liu Haoyue Dai Yong Ji Weijie Chen Xian Tang Jihai Cui Mifen Qiao Xu | 2014 | Chemical Engineering Journal2014，257，： | 1 |
| 10 | miR-17-5p as a Novel Prognostic Marker for Hepatocellular Carcinoma显示文摘 | Ling Chen Meng Jiang Weijie Yuan Huihuan Tang | 2012 | Journal of Investigative Surgery2012，，3： | 1 |
| 11 | Direct infection of SARS-CoV-2 in human iPSC-derived 3D cardiac organoids recapitulates COVID-19 myocarditis显示文摘Dear editor,The pandemic of coronavirus disease-19(COVID-19)has lasted for more than three years,causing lots of extra death and posing a serious threat to public health.This pandemic swept the last global safety island in a matter of months,coinciding with the switch of zero-COVID policy of China.The causative agent,SARS-CoV-2,spreads globally and then lurks in the population with sporadic outbreaks in local areas.Meanwhile,the sequelae of convalescent COVID-19 patients receded slowly.The pantissue tropism of SARS-CoV-2 results in a wide range of symptoms in patients,including cardiovascular disorders.Cardiac complications occur in 20%–44%of hospitalized patients,which is an independent risk factor for COVID-19 mortality(Ma et al.,2022;Patone et al.,2022).Survivors of acute COVID-19 also have a substantial risk of cardiovascular disease burden lasting up to one year(Xie et al.,2022). | Weijie Wang Jinxuan Yang Pinfang Kang Jinsong Bai Xiaoli Feng Liuqi Huang Yiming Zhang Yuechun Wu Bi Tang Hongju Wang JianJie Jiang Minghua Li Bing Zhao Xinglou Yang | 2023 | Virologica Sinica2023，38，6： | 0 |
| 12 | Bright,photostable and long-circulating NIR-II nanoparticles for whole-process monitoring and evaluation of renal transplantation显示文摘Kidney transplantation is the gold standard for the treatment of end-stage renal diseases(ESRDs).However,the scarcity of donor kidneys has caused more and more ESRD patients to be stuck on the waiting list for transplant surgery.Improving the survival rate for renal grafts is an alternative solution to the shortage of donor kidneys.Therefore,real-time monitoring of the surgical process is crucial to the success of kidney transplantation,but efficient methods and techniques are lacking.Herein,a fluorescence technology based on bright,photostable and long-circulating aggregation-induced emission(AIE)active NIR-II nano-contrast agent DIPT-ICF nanoparticles for the whole-process monitoring and evaluation of renal transplantation has been reported.In the aggregated state,DIPT-ICF exhibits superior photophysical properties compared with the commercial dyes IR-26 and IR-1061.Besides,the long-circulating characteristic of the AIE nano-contrast agent helps to achieve renal angiography in kidney retrieval surgery,donor kidney quality evaluation,diagnosing vascular and ureteral complications,and assessment of renal graft reperfusion beyond renovascular reconstruction,which considerably outperforms the clinically approved indocyanine green(ICG). | Rongyuan Zhang Ping Shen Yu Xiong Tianjing Wu Gang Wang Yucheng Wang Liping Zhang Han Yang Wei He Jian Du Xuedong Wei Siwei Zhang Zijie Qiu Weijie Zhang Zheng Zhao Ben Zhong Tang | 2024 | National Science Review2024，11，2： | 0 |
| 13 | Compositional characteristics and toxicological responses of human lung epithelial cells to inhalable particles (PM_(10)) from ten typical biomass fuel combustions显示文摘As the primary component of haze,atmospheric inhalable particulate matters(PMio)are highly detri-mental to human health.Biomass combustion is one of China's most pivotal sources to aerosols pollution,inducing non-negligible emissions and uncertain risks.PMio samples directly from 10 representative biomass fuel combustion sources(2 groups covering the reality widely:straws of rice,wheat,corn,corncob,soybean,peanut,rape,sesame;and branches of pine,peach)were collected using the dilution channel sampler and analyzed for chemical compositions and in vitro cytotoxicity to human lung epithelial cell lines A549.The components of PMio are dominated by organic carbon(OC),followed by Water-soluble K+and Cl,and rich in metals Fe,Zn,Cr,and Ni.Generally,PMio emitted from biomass fuel combustions can weaken the antioxidant capacity of cells,and straws emissions,especially rape and peanut straws,show stronger ability to further induce oxidative stress and inflammatory damage than fuelwoods,owing to the key toxic roles of Cr,Ni,and Co.Therefore,reducing the specific source emis--sions of PMio from crop straw combustions rich in heavy metals could be an effective oriented strategy to improve environmental air quality and control aerosols pollution precisely for protecting public health. | Hanhan Li Mingwei Tang Xiaosan Luo Weijun Li Yuting Pang Weijie Huang Zhen Zhao Yaqian Wei Tengda Long Tariq Mehmood | 2023 | Particuology2023，，7： | 0 |
| 14 | FBXW7βloss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth显示文摘Continuous de novo fatty acid synthesis is required for the biosynthetic demands of tumor.FBXW7 is a highly mutated gene in CRC,but its biological functions in cancer are not fully characterized.Here,we report that FBXW7β,a FBXW7 isoform located in the cytoplasm and frequently mutated in CRC,is an E3 ligase of fatty acid synthase(FASN).Cancer-specific FBXW7βmutations that could not degrade FASN can lead to sustained lipogenesis in CRC.COP9 signalosome subunit 6(CSN6),an oncogenic marker of CRC,increases lipogenesis via interacting with and stabilizing FASN.Mechanistic studies show that CSN6 associates with both FBXW7βand FASN,and antagonizes FBXW7β’s activity by enhancing FBXW7βautoubiquitination and degradation,which in turn prevents FBXW7β-mediated FASN ubiquitination and degradation,thereby regulating lipogenesis positively.Both CSN6 and FASN are positively correlated in CRC,and CSN6-FASN axis,regulated by EGF,is responsible for poor prognosis of CRC.The EGF-CSN6-FASN axis promotes tumor growth and implies a treatment strategy of combination of orlistat and cetuximab.Patient-derived xenograft experiments prove the effectiveness of employing orlistat and cetuximab combination in suppressing tumor growth for CSN6/FASN-high CRC.Thus,CSN6-FASN axis reprograms lipogenesis to promote tumor growth and is a target for cancer intervening strategy in CRC. | Wenxia Wei Baifu Qin Weijie Wen Boyu Zhang Haidan Luo Yuzhi Wang Hui Xu Xiaoshan Xie Sicheng Liu Xin Jiang Mengan Wang Qin Tang Jiayu Zhang Runxiang Yang Zongmin Fan Haiwen Lyu Junzhong Lin Kai Li Mong-Hong Lee | 2023 | Signal Transduction and Targeted Therapy2023，8，6： | 0 |
| 15 | Tunable electronic band structure,luminescence properties and thermostability of(Gd_(1-x)La_(x))_(2)Si_(2)O_(7):Ce scintillator by adjusting La/Gd ratio显示文摘Mixed crystal strategy is an effective approach of improving the luminescence properties of optical materials and has been adopted widely in many systems.In this paper,the La-mixed Gd_(2)Si_(2)O_(7):Ce polycrystalline samples were successfully synthesized by a sol-gel method.The crystal structure and luminescence properties were confirmed and discussed by XRD,UV-Vis luminescence spectra,and XEL,respectively.The vacuum ultraviolet excitation spectra and thermoluminescence glow curves were also systematically investigated and discussed at varied temperature.A combination of the first-principles calculations and optical characterization experiments was employed to study the electronic band structure of host material,revealing that the band gap is narrowed and the 5d_(1) level of Ce^(3+) shifts to higher energy as the La content increases.The luminescence the rmo-stability and activation energy were also measured and calculated.It indicates that thermo-stability is strongly dependent on the La concentration.An effective approach is developed to tune the electronic band structure,luminescence properties and thermostability of(Gd_(1-x)La_(x))_(2)Si_(2)O_(7):Ce scintillator by adjusting La/Gd ratio. | Qinhua Wei Zhenzhen Zhou Weijie Zhang Gao Tang Qian Liu Laishun Qin Hongsheng Shi | 2021 | Journal of Rare Earths2021，39，6： | 0 |
| 16 | Silicon polarization switch based on symmetric polarization splitter-rotators显示文摘1.Introduction Silicon photonic integration is considered to be one of the most promising techniques in realizing high-density photonic integrated circuits because of its compact device size and CMOS compatible fabrication process.However,due to the large index contrast of silicon waveguides,silicon photonic devices are affected by the large polarization mode dispersion,polarization dependent loss and polarization dependent wavelength characteristics.Polarization transparent circuits and polarization diversity schemes,which have polarization rotators and splitters as common key devices,have been proposed to solve this issue[1–3]. | Defen Guo Kang Hou Weijie Tang Tao Chu | 2019 | Journal of Semiconductors2019，40，10： | 0 |
| 17 | Comparison of Wide-bandgap Devices in 1 kV,3 kW LLC Converters显示文摘Emerging wide-bandgap(WBG)devices,such as silicon carbide(SiC)MOSFETs and gallium nitride(GaN)high-electron-mobility transistors(HEMTs)provide new opportunities to realize high efficiency,high power density,and high reliability in several kHz,1 kV input,and several kW output applications.However,the performance comparison between SiC MOSFETs and GaN HEMTs in high-voltage,high-frequency,medium-high-power DC conversion applications have not yet been investigated thoroughly.Two 1 kV,3 kW LLC prototypes with GaN and SiC devices are built to perform a careful comparison of the prototypes in terms of parameters,power density,zero voltage switch realization,and overall efficiency.This provides guidance for the appropriate evaluation of WBG devices in high-voltage,high-frequency,and medium-high-power applications. | Zhanbiao Gu Jiacheng Tang Wenming Zhu Kaiqi Yao Zhesi Gao Weijie Shi Zhiliang Zhang Xiaoyong Ren | 2020 | Chinese Journal of Electrical Engineering2020，6，3： | 0 |
| 18 | Suspected Yellow Fever Case Determined to be Adverse Vaccine Reaction显示文摘Jiangxi Provincial Center for Disease Control and Prevention(Jiangxi CDC)received an alert at 23:45 on November 7,2019 from Nanchang Customs that yellow fever virus was detected in a foreign national.On November 8,county,municipal,and provincial CDCs of Jiangxi Province carried out epidemiological investigations to show that the suspected case was found in a 35-year-old male patient from Addis Ababa,Ethiopia.On November 5,this patient began to have yellow-fever-like symptoms such as onset of fever,chills,and headache. | Sheng Ding Ying Xiong Huanhong Pan Zhongjian Li Song Tang Xingkui Huang Jianxiong Li Yong Shi Weijie Fu Huijian Cheng Daping Che Xiaoqing Liu Wentao Song Jingwen Wu Yisheng zhou Jian Zhang Chao Li Jiandong Li | 2019 | China CDC weekly2019，1，4： | 0 |
| 19 | A randomized controlled trial to evaluate efficacy and safety of early conversion to a low-dose calcineurin inhibitor combined with sirolimus in renal transplant patients显示文摘Background:The calcineurin inhibitor(CNI)-based immune maintenance regimen that is commonly used after renal transplantation has greatly improved early graft survival after transplantation;however,the long-term prognosis of grafts has not been significantly improved.The nephrotoxicity of CNI drugs is one of the main risk factors for the poor long-term prognosis of grafts.Sirolimus(SRL)has been employed as an immunosuppressant in clinical practice for over 20 years and has been found to have no nephrotoxic effects on grafts.Presently,the regimen and timing of SRL application after renal transplantation vary,and clinical data are scarce.Multicenter prospective randomized controlled studies are particularly rare.This study aims to investigate the effects of early conversion to a low-dose CNI combined with SRL on the long-term prognosis of renal transplantation.Methods:Patients who receive four weeks of a standard regimen with CNI+mycophenolic acid(MPA)+glucocorticoid after renal transplantation in multiple transplant centers across China will be included in this study.At week 5,after the operation,patients in the experimental group will receive an additional administration of SRL,a reduction in the CNI drug doses,withdrawal of MPA medication,and maintenance of glucocorticoids.In addition,patients in the control group will receive the maintained standard of care.The patients’vital signs,routine blood tests,routine urine tests,blood biochemistry,serum creatinine,BK virus(BKV)/cytomegalovirus(CMV),and trough concentrations of CNI drugs and SRL at the baseline and weeks 12,24,36,48,72,and 104 after conversion will be recorded.Patient survival,graft survival,and estimated glomerular filtration rate will be calculated,and concomitant medications and adverse events will also be recorded.Conclusion:The study data will be utilized to evaluate the efficacy and safety of early conversion to low-dose CNIs combined with SRL in renal transplant patients. | Xiang Zheng Weijie Zhang Hua Zhou Ronghua Cao Zhangfei Shou Shuwei Zhang Ying Cheng Xuchun Chen Chenguang Ding Zuofu Tang Ning Li Shaohua Shi Qiang Zhou Qiuyuan Chen Gang Chen Zheng Chen Peijun Zhou Xiaopeng Hu Xiaodong Zhang Ning Na Wei Wang | 2022 | Chinese Medical Journal2022，，13： | 0 |
| 20 | Federated Learning Model for Auto Insurance Rate Setting Based on Tweedie Distribution显示文摘In the assessment of car insurance claims,the claim rate for car insurance presents a highly skewed probability distribution,which is typically modeled using Tweedie distribution.The traditional approach to obtaining the Tweedie regression model involves training on a centralized dataset,when the data is provided by multiple parties,training a privacy-preserving Tweedie regression model without exchanging raw data becomes a challenge.To address this issue,this study introduces a novel vertical federated learning-based Tweedie regression algorithm for multi-party auto insurance rate setting in data silos.The algorithm can keep sensitive data locally and uses privacy-preserving techniques to achieve intersection operations between the two parties holding the data.After determining which entities are shared,the participants train the model locally using the shared entity data to obtain the local generalized linear model intermediate parameters.The homomorphic encryption algorithms are introduced to interact with and update the model intermediate parameters to collaboratively complete the joint training of the car insurance rate-setting model.Performance tests on two publicly available datasets show that the proposed federated Tweedie regression algorithm can effectively generate Tweedie regression models that leverage the value of data fromboth partieswithout exchanging data.The assessment results of the scheme approach those of the Tweedie regressionmodel learned fromcentralized data,and outperformthe Tweedie regressionmodel learned independently by a single party. | Tao Yin Changgen Peng Weijie Tan Dequan Xu Hanlin Tang | 2024 | Computer Modeling in Engineering & Sciences2024，138，1： | 0 |
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