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| 1 | Thiolactone copolymer donor gifts organic solar cells a 16.72% efficiency显示文摘Since 1995,bulk-heterojunction organic solar cells consisting of one or two organic donors and one or two organic acceptors have been fighting for high power conversion efficiencies(PCEs)and good stability[1].Until recent years,this next-generation photovoltaic technology starts to offer decent PCEs,shedding the light on commercialization,and attracting great attention again[2-14].Compared w让h the continuously emerging highperformance nonfullerene acceptors,high-performance donors are rare. | Ji Xiong Ke Jin Yufan Jiang Jianqiang Qin Tan Wang Jinfeng Liu Qishi Liu Haili Peng Xiongfeng Li Anxin Sun Xianyi Meng Lixiu Zhang Ling Liu Wenting Li Zhimin Fang Xue Jia Zuo Xiao Yaqing Feng Xiaotao Zhang Kuan Sun Shangfeng Yang Shengwei Shi Liming Ding | 2019 | Science Bulletin2019，64，21： | 17 |
| 2 | Thrombolysis with alteplase 3-4.5 hours after acute ischaemic stroke:the first multicentre,phase III trial in China显示文摘background and purpose Data on the efficacy and safety of alteplase for acute ischaemic stroke(AIS)administered 3-4.5 hours after the onset of stroke symptoms in Chinese patients is limited.We sought to determine whether AIS patients would benefit from thrombolysis with alteplase between 3 and 4.5 hours after the onset of stroke symptoms in a prospective,multicentre,single-arm trial in China.Materials and methods Eligible AIS patients were given 0.9 mg/kg alteplase intravenously.The primary efficacy endpoint was a favourable outcome at 3 months,defined as a score of 0 or 1 on the modified Rankin Scale.Thresholds for the primary efficacy endpoint were determined to be 40%based on the literature review.The primary safety endpoint was symptomatic intracranial haemorrhage(sICH)according to the European Cooperative Acute Stroke Study III(ECASS III)trial definition.Post hoc analysis between this study and the ECASS III trial were compared using the propensity score matching(PSM)method.results A total of 120 eligible AIS patients from 11 sites in China received thrombolysis therapy in this study.The median time from onset of symptoms to needle was 3 hours 54 min.The percentage of patients with a favourable outcome was 63.3%(95%CI 54.4 to 71.4),significantly higher than the predefined threshold(p<0.0001).Three patients(2.5%,95%CI 0.5 to 7.1)had sICH,including two fatal sICH.Six patients died within 3 months after treatment.The post hoc PSM analysis showed a numerically higher rate of the primary efficacy endpoint in this study(63.3%)than the matched placebo arm(56.7%)in the ECASS III trial.Conclusions Intravenous alteplase with a standard dose administered between 3 and 4.5 hours after onset of symptoms is effective and safe for Chinese AIS patients. | Huaguang Zheng Yi Yang Huisheng Chen Chuanling Li Yangkun Chen Fu-Dong Shi Li Yang Xiaoping Cui Zuneng Lu Yanling Liang Songbiao Cui Anding Xu Yiqing Wu Yaqing Sun Yongjun Wang | 2020 | Stroke & Vascular Neurology2020，5，3： | 4 |
| 3 | Whole-Genome Sequences Analysis Displays Relationship of SARS-CoV-2 Delta Variant Between Four Local Cases and Passengers of a Flight from South Africa—Shenzhen City,Guangdong Province,China,June 2021显示文摘On June 14,2021,a customs officer(Case A)went to the infirmary at Baoan International Airport in Shenzhen due to a runny nose and fever.He was admitted to the Central Hospital of Baoan immediately.This patient preliminarily tested positive for coronavirus disease 2019(COVID-19)infection,caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),using a quantitative realtime reverse transcription polymerase chain reaction(qRT-PCR)method in this hospital.Then,a mixed specimen of nasopharyngeal swab. | Yaqing He Renli Zhang Qiuying Lyu Bo Peng Shujiang Mei Ying Sun Dongfeng Kong Chaoqiong Peng Ziquan Lyu Xinyi Wei Can Zhu Xiaoliang Xiao Shimin Li Qingju Lu Jiancheng Chen Hang Zhang Xuan Zou Tiejian Feng Long Chen | 2021 | China CDC weekly2021，3，50： | 3 |
| 4 | Metabolomics analysis for skin ulceration syndrome of Apostichopus japonicus based on UPLC/Q-TOF MS显示文摘Skin ulceration syndrome(SUS)is the main diseases aff ected the development of sea cucumber(Apostichopus japonicus)culture industries.To better observe the changes in the sea cucumber A.japonicus with SUS and understand the pathogenesis of the disease,activities of superoxide dismutase(SOD),catalase(CAT),and level of malondialdehyde(MDA)in coelomic fluid were detected using the Assay Kit and metabolites in the body wall were assessed using ultra-performance liquid chromatography and quadrupole-time of flight mass spectrometry.The results indicated that level of MDA was increased during SUS compared with healthy individuals(P<0.01),but activities of SOD and CAT were reduced(P<0.05).In metabolomics analysis,metabolites,such as adenosine,choline,betaine aldehyde,palmitic acid,and taurine,were found to be upregulated and 2-oxoadipic acid,anthranilic acid(vitamin L1),thioetheramide-PC,cholesterol-3-sulfate,and pentadecanoic acid were downregulated(VIP>1 and P<0.1).Pathway enrichment analysis indicated most enrichment of KEGG pathways were mainly related to energy metabolism,immunity,and osmoregulation such as ABC transporters,glycine,serine and threonine metabolism,tryptophan metabolism and neuroactive ligand-receptor interaction.Our study reflected the difference in enzyme activity and metabolites between A.japonicus with SUS and those without,which will provide reference data for investigating SUS. | Yang ZHANG Youquan WANG Xiaoyu LIU Beichen DING Yi SUN Yaqing CHANG Jun DING | 2021 | Journal of Oceanology and Limnology2021，39，4： | 2 |
| 5 | A critical role of foxp3a-positive regulatory T cells in maintaining immune homeostasis in zebrafish testis development显示文摘Suppressive regulatory T cells(Treg cells)play a vital role in preventing autoimmunity and restraining excessive immune response to both self-and non-self-antigens.Studies on humans and mice show that the Forkhead box p3(Foxp3)is a key regulatory gene for the development and function of Treg cells.In zebrafish,Treg cells have been identified by using foxp3a as a reliable marker.However,little is known about the function of foxp3a and Treg cells in gonadal development and sex differentiation.Here,we show that foxp3a is essential for maintaining immune homeostasis in zebrafish testis development.We found that foxp3a was specifically expressed in a subset of T cells in zebrafish testis,while knockout of foxp3a led to deficiency of foxp3a-positive Treg cells in the testis.More than 80%of foxp3a^(-/-)mutants developed as subfertile males,and the rest of the mutants developed as fertile females with decreased ovulation.Further study revealed that foxp3a^(-/-)mutants had a delayed juvenile ovary-to-testis transition in definite males and sex reversal in about half of the definite females,which led to a dominance of later male development.Owing to the absence of foxp3a-positive Treg cells in the differentiating testis of foxp3a^(-/-)mutants,abundant T cells and macrophages expand to disrupt an immunosuppressive milieu,resulting in defective development of germ cells and gonadal somatic cells and leading to development of infertile males.Therefore,our study reveals that foxp3a-positive Treg cells play an essential role in the orchestration of gonadal development and sex differentiation in zebrafish. | Xianmei Li Fenghua Zhang Nan Wu Ding Ye Yaqing Wang Xiaofan Zhang Yonghua Sun Yong-An Zhang | 2020 | Journal of Genetics and Genomics2020，47，9： | 2 |
| 6 | Potentials of crop residues for commercial energy production in China: A geographic and economic analysis显示文摘 | Huanguang Qiu Laixiang Sun Xinliang Xu Yaqing Cai Junfei Bai | 2014 | Biomass and Bioenergy2014，，： | 1 |
| 7 | Application of gelatin as a binder for the sulfur cathode in lithium- sulfur batteries显示文摘 | Sun Jing Huang Yaqing Wang Weikun | 2008 | Electrochimica Acta2008，10，6： | 1 |
| 8 | Race-specific genetic risk score is more accurate than nonrace-specific genetic risk score for predicting prostate cancer and high-grade diseases显示文摘基因风险分数(GRS ) 基于疾病联系风险的单个核苷酸多型性(SNP ) 是能被用来除了家庭历史为特定的疾病提供继承信息的一个增进知识的工具。然而,当计算 GRS 时,在一个特定的种族组被含有的 SNP 是否仅仅应该被使用,仍然是未知的。学习是为在 1338 个病人之中预言前列腺癌症(PCa ) 比较赛跑特定的 GRS 和 nonrace 特定的 GRS 的表演的这的目的在上海经历了前列腺活体检视,中国。赛跑特定的 GRS 与七 PCa 联系风险的 SNP 被计算在东方亚洲人(GRS7 ) 含有,并且 nonrace 特定的 GRS 基于 76 PCa 联系风险的 SNP 是计算的在至少一个种族组(GRS76 ) 含有。分别地, GRS7 和 GRS76 的工具在学习人口是 1.19 和 1.85。更高的 GRS7 和 GRS76 在 univariate 和 multivariate 分析是为 PCa 和高级 PCa 的独立预言者。GRS7 为区别 PCa (0.602 对 0.573 ) 和高级 PCa (0.603 对 0.575 ) 比 GRS76 在操作接收装置的曲线(AUC ) 下面有一个更好的区域但是没到达统计意义。有的 GRS7 一更好(多达 13% 在不同截止) 积极预兆的价值(PPV ) 比 GRS76。在结论,赛跑特定的 GRS 是更柔韧的并且当比用没被显示与东方亚洲人被联系的 SNP 计算的 GRS 在东方亚洲人预言 PCa 时,有更好的表演。 | Rong Na Dingwei Ye Jun Qi Fang Liu Xiaoling Lin Brian T Helfand Charles B Brendler Carly Conran Jian Gong Yishuo Wu Xu Gao Yaqing Chen S Lilly Zheng Zengnan Mo Qiang Ding Yinghao Sun Jianfeng Xu | 2016 | Asian Journal of Andrology2016，18，4： | 1 |
| 9 | Biomimetic nanochannel membrane for cascade response of borate and cis-hydroxyl compounds:An IMP logic gate device显示文摘Biomimetic nanodevice is an important branch to expand the potential applications of artificial nanochannels. Here, we constructed nanochannels for cascade response of borate and cis-hydroxyl compounds by modifying the nanochannels of track-etched polycarbonate (TEPC) membranes with polyvinyl alcohol (PVA). Firstly, borate bound to PVA and increased the negative charge density on the surface of the nanochannels, which obstructed the transport of 1,5-naphthalene disulfonate (NDS2-). Subsequently, the addition of cis-hydroxyl compounds induced leaving of borate due to the stronger binding affinities between borate and cis-hydroxyl compounds, which reduced the negative charge density on nanochannels and then enhanced the transport of NDS2-. The cascade response of the nanochannels also accord with the properties of IMP (implication) logic gate. In addition, such nanochannels showed good reproducibility and reversibility. Therefore, this cascade response model based on nanochannels has the potential to be used as switches in area of actuators and biosensors, and is also expected to be used to understand the interaction of substances in nanoscale and simulate the physiological functions of boron. | Meitao Deng Meng Yang Yaqing Xu Yuqiong Sun Qing Wang Jianbo Liu Jin Huang Xiaohai Yang Kemin Wang | 2019 | Chinese Chemical Letters2019，30，7： | 1 |
| 10 | A landscape of differentiated biological processes involved in the initiation of sex differentiation in zebrafish显示文摘Zebrafish(Danio rerio)has been used as a promising animal model to study gonadal development and gametogenesis.Although previous studies have identified critical molecules participating in zebrafish gonad differentiation,a landscape view of the biological processes involved in this process is still lacking.Here we isolated intact zebrafish differentiating gonads,at 25 days post-fertilization(dpf)and 30 dpf and conducted RNA-seq analyses on the juvenile gonads that tended to develop into ovaries or testes.Our study demonstrates that the juvenile ovary and testis at 25 dpf and 30 dpf are different at the biological process level.During ovary differentiation,the biological processes related to metabolic activities in the production of energy and maternal substances,RNA degradation,and DNA repair were enriched.During testis differentiation,the biological processes related to cell proliferation,differentiation,and morphogenesis were enriched,with a total of 15 signaling pathways.Notably,we reveal that the immune-related processes are extensively involved in the regulation of testis development.Overall,this study provides a landscape of differentiated biological processes and novel insights into the initiation of sex differentiation in zebrafish. | Ding Ye Yi-Xuan Tu Houpeng Wang Mudan He Yaqing Wang Zhengfang Chen Zhen-Xia Chen Yonghua Sun | 2022 | Water Biology and Security2022，1，3： | 1 |
| 11 | Endoscopic polypectomy for pacemaker patients:is it safe显示文摘 | Yue Li Zelong Han Yaqing Sun | 2015 | ANZ Journal of Surgery2015，85，11： | 1 |
| 12 | Acetic acid additive in NaNO_(3)aqueous electrolyte for long-lifespan Mg-air batteries显示文摘Mg-air batteries have attracted tremendous attention as a potential next-generation power source for portable electronics and e-transportation due to their remarkable high theoretical volumetric energy density,environmental sustainability,and cost-effectiveness.However,the fast hydrogen evolution reaction(HER)in NaCl-based aqueous electrolytes impairs the performance of Mg-air batteries and leads to poor specific capacity,low energy density,and low utilization.Thus,the conventionally used NaCl solute was proposed to be replaced by NaNO_(3)and acetic acid additive as a corrosion inhibitor,therefore an electrolyte engineering for long-life time Mg-air batteries is reported.The resulting Mg-air batteries based on this optimized electrolyte demonstrate an improved discharge voltage reaching~1.8 V for initial 5 h at a current density of 0.5 mA/cm^(2) and significantly prolonged cells'operational lifetime to over 360 h,in contrast to only~17 h observed in NaCl electrolyte.X-ray photoelectron spectroscopy and time-of-flight secondary ion mass spectrometry were employed to analyse the composition of surface film and scanning electron microscopy combined with transmission electron microscopy to clarify the morphology changes of the surface layer as a function of acetic acid addition.The thorough studies of chemical composition and morphology of corrosion products have allowed us to elucidate the working mechanism of Mg anode in this optimized electrolyte for Mg-air batteries. | Yaqing Zhou Fan Sun Gunahua Lin Sandrine Zanna Antoine Seyeux Philippe Marcus Jolanta´Swiatowska | 2024 | Journal of Magnesium and Alloys2024，12，2： | 0 |
| 13 | Genome Characterization of COVID-19 Lineage B.1.1.7 Detected in the First Six Patients of a Cluster Outbreak——Shenzhen City,Guangdong Province,China,May 2021显示文摘Screening for coronavirus disease 2019(COVID-19)virus,also known as SARS-CoV-2,infection every seven days was performed for high-risk populations who worked at the Yantian Port in Yantian District,Shenzhen City,Guangdong Province.On May 20,2021,an oropharyngeal swab from a 44-year-old male(Case A)tested preliminarily positive for COVID-19 by a quantitative real-time reverse transcription polymerase chain reaction(RT-qPCR)method in a third-party laboratory. | Yaqing He Peihua Niu Bo Peng Ying Sun Ziquan Lyu Renli Zhang Xiang Zhao Yang Song Yenan Feng Xiujuan Tang Dongfeng Kong Xinyi Wei Can Zhu Qingju Lu Shimin Li Xiaoliang Xiao Weiwen Liu Junjia He Junjie Xia Long Chen Xuan Zou Tiejian Feng | 2021 | China CDC weekly2021，3，25： | 0 |
| 14 | Climate change in the Hongliujing area of Lop Nur over the past 200 years revealed by the stable oxygen isotopes of Tamarix cones显示文摘The layers of Tamarix cones within sedimentary deposits in arid regions have significant chronological and paleoenvironmental implications.Here,we compare the δ^(18)O values of Tamarix cones in the Hongliujing area of Lop Nur with meteorological data for the Ruoqiang meteorological station for 1960-2019 AD.Linear regression analysis was used to reconstruct the average temperature for April and the precipitation for November in the Hongliujing area over the past 200 years.The results showed that the δ^(18)O values were significantly negatively correlated with the temperature for February,April,May,August,December,and with the annual mean temperature;significantly negatively correlated with the precipitation for February and April;significantly negatively correlated with the sunshine hours for March and May;significantly positively correlated with the sunshine hours for February,July,August,October,and December,and with the annual mean values;and significantly correlated with the relative humidity for April,July,August,September,October,and November,and with the annual mean values.Based on the δ^(18)O record of the past 200 years,the Hongliujing area experienced two warm-wet periods(1874-1932 and 2004-2019 AD)and two cold-dry periods(1832–1873 and 1933-2003 AD).Thus,the climate was characterized by alternating warm-wet and cold-dry conditions.Wavelet analysis revealed three main cycles:45 years,29 years,and 14 years. | Zhiguang LI Yaqing DONG Haoyu ZHANG Hongxiao SUN Danyang JIA Shikai SONG Yuanjie ZHAO | 2023 | Frontiers of Earth Science2023，17，4： | 0 |
| 15 | 6-2 Recent Progress of the SSC-Linac显示文摘SSC-Linac[1] as the injector for the Separated Sector Cyclotron (SSC), is being constructed at national labo-ratory Heavy Ion Research Facility at Lanzhou (HIRFL). The injection and extraction energy are 3.7 keV/u and1.025 MeV/u, respectively. Fig. 1 shows the front end section of the SSC-Linac. The high charges state continuswave (CW) 4-rod RFQ has been designed and fabricated for some years. From the end of 2013, the commissioningof the RFQ was performed and the beam test was carried out in April 2014. In this paper the experiment resultwill be presented. | Yin Xuejun Yuan Youjin Zhang Xiaohu Lu Wang Du Heng Li Xiaoni Jiang Peiyong Li Zhongcan Wang Haonin Yang Yaqing Ma Lizhen Xu Zhe Zhang Xuezhen Sun Liangting Yao Qinggao Meng Jun Cai Guozhu He Yuan Zhao Hongwei Xia Jiawen Liu Ge Lu Yuanrong Zhu Kun Gao Shuli Yan Xueqing Chen Jiaer | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 16 | First Beam Commissioning of SSC-Linac as an Injector of SSC显示文摘The construction of the SSC-Linac has made significant progress in 2019.The first beam commissioning of SSC-Linac as an injector of the Separated Sector Cyclotron(SSC)was performed succssfully with ^(40)Ar^(7+) beam and the particle energy of 5.98 MeV/u was obtained at the exit of SSC on December 17,2019. | Du Heng Yin Xuejun Yang Weiqing Li Zhongshan Kong Qiyu Li Xiaoni Yang Shengli Qian Cheng WangHaoning Cong Yan Jin Peng Zhang Ruifeng Han Xiaodong Fu Xin Wang Kai Jing Long Zhang Yong Li Lili Xie Wenjun Xu Xiaowei Wang Shaoming Chen Wenjun Liu Xiaojun Yue Min An Jingrui Zhang Xiang Yan Huaihai Feng Anhui Zhang Shuai Zhang Yongbo Sun Peng Zhu Tieming Sha Xiaoping Xu Jianye Sun Xiaolong Su Xuemin Li Anping Yan Tailai Meng Jun Zhang Wei Wu Junxia Yao Qinggao Yang Yaqing Xu Zhe Sun Liangting Gao Daqing Yuan Youjin Yang Jiancheng Xia Jiawen | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 17 | A phylogeny of the Passerida(Aves: Passeriformes)based on mitochondrial 12S ribosomal RNA gene显示文摘Background: Passerida is the largest avian radiation within the order Passeriformes. Current understanding of the high-level relationships within Passerida is based on DNA–DNA hybridizations; however, the phylogenetic relationships within this assemblage have been the subject of many debates.Methods: We analyzed the 12 S ribosomal RNA gene from 49 species of Passerida, representing 14 currently recognized families, to outline the phylogenetic relationships within this group.Results: Our results identified the monophyly of the three superfamilies in Passerida: Sylvioidea, Muscicapoidea and Passeroidea. However, current delimitation of some species is at variance with our phylogeny estimate. First, the Parus major, which had been placed as a distinct clade sister to Sylvioidea was identified as a member of the super family;second, the genus Regulus was united with the Sturnidae and nested in the Muscicapoidea clade instead of being a clade of Passerida.Conclusion: Our results were consistent with Johansson's study of the three superfamilies except for the al ocation of two families, Paridae and Regulidae. | Lina Wu Yanfeng Sun Juyong Li Yaqing Li Yuefeng Wu Dongming Li | 2015 | Chinese Birds2015，，1： | 0 |
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