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| 1 | Stenting for symptomatic intracranial arterial stenosis in China:1-year outcome of a multicentre registry study显示文摘background and purpose A multicentre prospective registry study of individually tailored stenting for a patient with symptomatic intracranial atherosclerotic stenosis(ICAS)combined with poor collaterals in China showed that the short-term safety and efficacy of stenting was acceptable.However,it remained uncertain whether the low event rate could be of a long term.We reported the 1-year outcome of this registry study to evaluate the long-term efficacy of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.Methods Patients with symptomatic ICAS caused by 70%-99% stenosis located at the intracranial internal carotid,middle cerebral,intracranial vertebral or basilar arteries combined with poor collaterals were enrolled.Balloon-mounted stent or balloon plus self-expanding stent were selected based on the ease of vascular access and lesion morphology determined by the operators.The primary outcome was the rate of 30-day stroke,transient ischaemic attack and death,and 12-month ischaemic stroke within the same vascular territory,haemorrhagic stroke and vascular death after stenting.results From September 2013 to January 2015,300 patients(ages 58.3±9.78 years)were recruited.Among them,159 patients were treated with balloon-mounted stent and 141 with balloon plus self-expanding stent.During the 1-year follow-up,25 patients had a primary end point event.The probability of primary outcome at 1 year was 8.1%(95% CI 5.3% to 11.7%).In 76 patients with digital subtraction angiography follow-up,27.6%(21/76)had re-stenosis≥50% and 18.4%(14/76)had re-stenosis≥70%.No baseline characteristic was associated with the primary outcome.Conclusion The event rate remains low over 1 year of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.Further randomised trial of comparing individually tailored stenting with best medical therapy is needed. | Ning Ma Yong Zhang Jie Shuai Changchun Jiang Qiyi Zhu Kangning Chen Li Liu Baomin Li Xiangqun Shi Lianbo Gao Yajie Liu Feng Wang Yongli Li Tieyan Liu Hongbo Zheng Dapeng Mo Feng Gao Yilong Wang Yongjun Wang Lei Feng Zhongrong Miao | 2018 | Stroke & Vascular Neurology2018，3，3： | 29 |
| 2 | Status and development of mineral wool made from molten blast furnace slag显示文摘This study describes the characteristics of mineral wool and its applications,and also introduces the traditional process of mineral wool made from molten blast furnace(BF) slag.Compared with high energy consumption of the traditional process,the production of mineral wool by using molten BF slag will be able to take full advantage of the sensible heat of molten slag,and also reduce production costs.However,there are also further issues to resolve such as how to obtain the required amount of molten BF slag and how to make it homogeneous.Based on the physical and chemical properties of the molten BF slag,the investigation into the relationship between temperature and viscosity under different acidity coefficients of the slag and silicon mixture was conducted.Combined with the crystallization and phase diagram of slag wool,its heat resistance,water resistance,durability and corrosion resistance were analyzed.Finally,trends of the technology development are proposed. | XIAO Yongli LIU Yin LI Yongqian | 2011 | Baosteel Technical Research2011，5，2： | 16 |
| 3 | Preliminary analysis on the relationships between Tibetan Plateau NDVI change and its surface heat source and precipitation of China显示文摘Using the automatic weather station data obtained from the Tibetan Plateau (TP), the normalized dif- ference vegetation index and the monthly precipitation data of China and by the methods of correlation and composite analysis, preliminary analytical results are achieved concerning the relationships be- tween TP NDVI change and its surface heat source and precipitation of China. The results of our re- search may lead to the following conclusions: (1) A positive correlation relationship exists between TP NDVI change and its surface heat source, including the sensible heat and the latent heat. As to the correlation of the former, it is more remarkable in western TP than in eastern TP, and as to the correla- tion of the latter, however it turns out contrary. (2) With the improvement of TP vegetation, its surface heat source of every season is also mainly reinforced, especially in summer. As to the contribution of the sensible heat and the latent heat to the increment of the TP surface heat source intensity, the for- mer is comparatively more significant than the latter in winter and spring, while in summer and autumn, the two have almost the same importance. (3) The correlation coefficient between summer NDVI over TP and the corresponding period precipitation of China displays a belt distribution of '+?+' from south to north China. (4) Anomalous surface heating field over TP derived from vegetation change is probably an important factor to affect summer precipitation of China. | HUA Wei FAN GuangZhou ZHOU DingWen NI ChangJian LI XueMin WANG YongLi LIU YaQin HUANG XianLun | 2008 | Science China Earth Sciences2008，51，5： | 14 |
| 4 | Effect of stimulating acupoint Guanyuan(CV 4) on lower back pain by burning moxa heat for different time lengths: a randomized controlled clinical trial显示文摘OBJECTIVE: To investigate the effect of different heat-stimulating time lengths on lower back pain.METHODS: Forty participants were randomly assigned to four groups of various heating time lengths. The short heating time length group(SL),moderate heating time length group(ML), and long heating time length group(LL) respectively received 15, 30, and 60 min of moxibustion therapy stimulating the acupoint Guanyuan(CV 4). The conventional acupuncture group(CA) received needle acupuncture treatment as a control group. The participants were treated continuously over a 2-week treatment period for a total of 10 sessions, with five sessions given per week. Participants were assessed weekly by blinded assessors, using the visual analogue scale(VAS) and Roland Morris Questionnaire(RMQ).RESULTS: The VAS and RMQ scores reduced in all four groups during treatment. There were significant differences in VAS scores(P < 0.01) and RMQ scores(P < 0.01) between before treatment and after 2 weeks of treatment in the LL group. After treatment, the LL group reported significantly lower VAS scores compared with the CA group, ML group,and SL group(P < 0.05).CONCLUSION: The long and moderate lengths of heat-stimulating time of 30 and 60 min may be more effective for relieving lower back pain than that of short stimulating time lengths. | Xu Jianfeng Lin Ruizhu Wu Yongli Wang Yingxu Liu Jian Zhang Yanling Zhang Yuequan Xi Chaolei Wu Qiang Li Xinjian | 2015 | Journal of Traditional Chinese Medicine2015，35，1： | 13 |
| 5 | Branched tetraether lipids in Chinese soils:Evaluating the fidelity of MBT/CBT proxies as paleoenvironmental proxies显示文摘The ubiquitous occurrence of branched glycerol dialkyl glycerol tetraethers(br GDGTs) in soils has allowed development of new proxies for reconstruction of past climate and environment. The methylation and cyclization degrees of br GDGTs, expressed as MBT and CBT, respectively, are reported to be mainly controlled by mean annual air temperature(MAAT) and soil p H. However, the br GDGT-derived temperatures and soil p H scatter widely when data from different environmental conditions are considered. In this study, we collected over 300 soil samples from China, which are representative of humid(Xishuangbanna, Guangzhou, and Shanghai), semi-arid(Dongying) and semi-arid/arid(Lanzhou, Tibetan Plateau) regions. Collectively we have the most extensive dataset that broadly characterizes the distribution of br GDGTs according to climate zones in China. The overall data demonstrate that the MBT/CBT derived temperatures better match the measured MAATs in humid and non-alkaline regions than those from regions of low MAP(<400 mm/yr) and above neutral soil p H(>7.0–7.5). Similarly, CBT describes soil p H much better in humid and non-alkaline soils than in semi-arid/arid and alkaline soils; the semi-arid/arid and alkaline soils tend to show a positive correlation between soil p H and CBT, which contradicts that in the humid and non-alkaline soils. While soil p H, MAAT and mean annual precipitation(MAP) are dominating factors controlling the br GDGT distribution across all climate zones, conductivity, total organic carbon and total nitrogen, as well as soil water content can also play an important role locally. Removing br GDGT-II resulted in a revised CBT index that provides more accurate estimation of p H, especially in semi-arid/arid and alkaline soils. The overall Chinese dataset demonstrates that continental air temperature derived from br GDGT-proxies can vastly deviate from real measurements and should be used with extreme caution in paleo-climate or-environment studies. | ZHENG FengFeng ZHANG ChuanLun CHEN YuFei LI FuYan MA CenLing PU Yang ZHU YuanQing WANG YongLi LIU WeiGuo | 2016 | Science China Earth Sciences2016，59，7： | 10 |
| 6 | Middle–Upper Ordovician(Darriwilian–Early Katian) Positive Carbon Isotope Excursions in the Northern Tarim Basin, Northwest China: Implications for Stratigraphic Correlation and Paleoclimate显示文摘Three positive carbon isotope excursions are reported from Middle–Upper Ordovician in Tahe oil-gas field, northern Tarim Basin. Based on conodont biostratigraphy, the Middle Darriwilian Isotope Carbon Excursion(MDICE) and the Guttenberg Carbon Isotope Excursion(GICE) are identified from Darriwilian to Early Katian by the aid of whole-rock carbon isotope data from two well cores. Positive excursion within conodont Pygodus anserinus zone is developed in Early Sandbian, and the fluctuation range is no less than MDICE. Because the range of this excursion in the generalized global carbon isotope curve is short, previous studies paid little attention to it, and named Early Sandbian Isotope Carbon Excursion(ESICE) in this paper. Furthermore, these positive excursions are not directly related to sea level fluctuations and the MDICE and GICE identified in northern Tarim can be globally correlated to that in southern China, North America, South America, and Europe. The Saergan Fm. source rocks of Middle-Upper Ordovician in Kalpin Dawangou outcrop are in accord with the geologic time of MDICE and ESICE, and GICE have strong ties to the source rock of Lianglitag Fm. in basin. Abundant organic carbon burial is an important factor in genesis of positive isotope carbon excursions. Positive oxygen isotope excursion, conodont fauna turnover, decreased conodont total diversity, and the change of sedimentary facies indicated that dramatic changes of paleoceanographic environment of Early-Middle Ordovician in Tarim Basin started from the end of Darriwillian, and an obvious icehouse climate of Late Ordovician occurred in ESICE. | Cunge Liu Guorong Li Dawei Wang Yongli Liu Mingxia Luo Xiaoming Shao | 2016 | Journal of Earth Science2016，27，2： | 9 |
| 7 | Correlation between BRAF^(V600E) mutation and clinicopathological features in pediatric papillary thyroid carcinoma显示文摘In adults, the presence of the BRAF^(V600E) mutation in papillary thyroid cancer(PTC) has been demonstrated to be strongly associated with aggressive cancer-cell characteristics and poor patient prognosis. In contrast, the frequency of this mutation in pediatric PTC has undergone limited study, and the few available estimates range from 0 to 63%. Furthermore, the role of the BRAF^(V600E) mutation in pediatric PTC is controversial; thus, the present study aimed to investigate the prevalence and role of the BRAF^(V600E) mutation in48 pediatric patients with PTC, aged 3–13 years. Of these patients, 41 were diagnosed with classic PTC, five were found to have a follicular variant of PTC, and two to exhibit a diffuse sclerosing PTC variant. The BRAF^(V600E) mutation was identified to be present in 35.4% of the 48 analyzed patients, and in 41.5% of the patients diagnosed with classical PTC. Furthermore, the presence of the BRAF^(V600E) mutation was found to be associated with a patient age at diagnosis of less than ten years(P=0.011), the performance of a thyroidectomy(P=0.03), exhibited tumor multifocality(P=0.02) and/or extra-thyroidal invasion(P=0.003), and both a low MACIS(Metastases, Age, Completeness of resection, Invasion, Size)(P=0.036) and AMES(Age, Metastasis, Extent of tumor,Size)(P=0.001)score. Together, these data suggest that the presence of the BRAF^(V600E) mutation may be negatively correlated with partial aggressive clinicopathological features of pediatric PTC. | Jiangqiao Geng Huanmin Wang Yuanhu Liu Jun Tai Yaqiong Jin Jie Zhang Lejian He Libing Fu Hong Qin Yingluan Song Jinzhu Su Aiying Zhang Xin Wen Yongli Guo Xin Ni | 2017 | Science China(Life Sciences)2017，60，7： | 9 |
| 8 | Warming moxibustion attenuates inflammation and cartilage degradation in experimental rabbit knee osteoarthritis显示文摘OBJECTIVE:To explore the molecular mechanism of warming moxibustion(WM)in knee osteoarthritis(KOA).METHODS:The knee joints of 40 New Zealand rabbits were placed in a plaster cast in an extended position to establish a KOA model.The animals were randomly divided into four groups:the control group,model group,WM group,and diclofenac(DF)group.Hematoxylin-eosin staining and the modified Mankin score were applied to evaluate the histopathological changes.Chondrocyte apoptosis was determined by the terminal deoxynucleotidyl transferase dUTP nick end labeling(TUNEL)assay.Western blotting and real-time quantitative polymerase chain reaction were performed to measure the expression of interleukin-1β(IL-1β),prostaglandin E receptor 3(PTGER3),a disintegrin-like and metalloproteinase with thrombospondin type-1 motifs-5(ADAMTS-5),matrix metalloproteinase-13(MMP-13),and C-terminal telopeptides of collagen typeⅡ(CTX-Ⅱ)in cartilage tissues of the different groups.The concentrations of IL-1β,PTGER3,and CTX-Ⅱin serum were detected by the enzyme-linked immunosorbent assay.RESULTS:Rabbits with KOA in the WM and DF groups showed significantly reduced cartilage erosion and Mankin scores,compared with the untreated rabbits.The number of TUNEL-positive cells observed in the WM group was much fewer than that in the model group.The expression of PTGER3,MMP-13,CTX-Ⅱ,IL-1β,and ADAMTS-5 in cartilage tissues was remarkably downregulated following therapy with WM and DF.Moreover,a marked reduction was observed in the serum levels of IL-1β,PTGER3,and CTX-Ⅱin the WM and DF groups.CONCLUSION:WM exerts favorable therapeutic effects on articular injuries of KOA by regulating the expression of inflammatory and cartilage degradation-related cytokines. | LIU Di WU Yongli LI Chun WANG Minglei MA Xiaoxiu LIU Junwei ZHANG Yanling YANG Lei | 2021 | Journal of Traditional Chinese Medicine2021，41，6： | 9 |
| 9 | Theoretical study on two-dimensional MoS2 piezoelectric nanogenerators显示文摘最近的实验表明了用薄片可以在机电的察觉到,便携技术,弥漫的计算,和植入的设备发现应用潜在的二维的瞬间 2 制作的那 nanogenerators。在现在的学习,我们理论上在 nanogenerator 产量上在瞬间 2 薄片检验了原子层的数字的效果。在方形波浪的应用紧张下面,有原子层的一个偶数的瞬间 2 薄片没展出压电的产量,由于投射倒置对称的存在。为有层的一个奇数的瞬间 2 薄片,由于倒置对称的缺乏,在另一方面,压电的产量电压和电流随层的数字的增加被产生,并且减少。而且,作为瞬间 2 ,薄片仅仅是一些原子厚,瞬间 2 nanogenerators 的电容比的小至少一个数量级基于 nanowire 、基于 nanofilm 的 nanogenerators,在高周波的应用程序启用瞬间 2 nanogenerators 的使用。我们的结果解释试验性的观察并且在优化并且设计二维的 nanogenerators 上提供指导。 | Yongli Zhou Wei Liu Xin Huang Aihua Zhang Yan Zhang Zhong Lin Wang | 2016 | Nano Research2016，9，3： | 8 |
| 10 | Sulfur dioxide and o-xylene co-treatment in biofilter:Performance, bacterial populations and bioaerosols emissions显示文摘Sulfur dioxide(SO_2) and benzene homologs are frequently present in the off-gas during the process of sewage sludge drying. A laboratory scale biofilter was set up to co-treat SO_2 and o-xylene in the present study. SO_2 and o-xylene could be removed simultaneously in a single biofilter. Their concentration ratio in the inlet stream influenced the removal efficiencies. It is worth noting that the removal of SO_2 could be enhanced when low concentrations of o-xylene were introduced into the biofilter. Pseudomonas sp., Paenibacillus sp., and Bacillus sp. were the main functional bacteria groups in the biofilter. Sulfur-oxidizing bacteria(SOB) and o-xylene-degrading bacteria(XB) thrived in the biofilter and their counts as well as their growth rate increased with the increase in amount of SO_2 and o-xylene supplied. The microbial populations differed in counts and species due to the properties and components of the compounds being treated in the biofilter. The presence of mixed substrates enhanced the diversity of the microbial population. During the treatment process, bioaerosols including potentially pathogenic bacteria, e.g., Acinetobacter lwoffii and Aeromonas sp., were emitted from the biofilter. Further investigation is needed to focus on the potential hazards caused by the bioaerosols emitted from waste gas treatment bioreactors. | Yongli Sun Song Xue Lin Li Wenjie Ding Junxin Liu Yunping Han | 2018 | Journal of Environmental Sciences2018，30，7： | 7 |
| 11 | Mathematical Analysis on the Uniqueness of Reverse Algorithm for Measuring Elastic-plastic Properties by Sharp Indentation显示文摘The reverse analysis provides a convenient method to determine four elastic-plastic parameters through an indentation curve such as Young s modulus E, hardness H, yield strength σy and strain hardening exponent n. In this paper, mathematical analysis on a reverse algorithm from Dao model (Dao et al., Acta Mater., 2001, 49, 3899) was carried out, which thought that only when 20 ≤E*/σ0.033≤ 26 and 0.3 | Yongli Huang Xiaofang Liu Yichun Zhou Zengsheng Ma Chunsheng Lu | 2011 | Journal of Materials Science & Technology2011，27，7： | 7 |
| 12 | The biological effect of recombinant humanized collagen on damaged skin induced by UV-photoaging:An in vivo study显示文摘The application of medical devices to repair skin damage is clinically accepted and natural polymer enjoys an important role in this field,such as collagen or hyaluronic acid,etc.However,the biosafety and efficacy of these implants are still challenged.In this study,a skin damage animal model was prepared by UV-photoaging and recombinant humanized type Ⅲ collagen(rhCol Ⅲ)was applied as a bioactive material to implant in vivo to study its biological effect,comparing with saline and uncrosslinked hyaluronic acid(HA).Animal skin conditions were non-invasively and dynamically monitored during the 8 weeks experiment.Histological observation,specific gene expression and other molecular biological methods were applied by the end of the animal experiment.The results indicated that rhCol Ⅲ could alleviate the skin photoaging caused by UV radiation,including reduce the thickening of epidermis and dermis,increase the secretion of Collagen Ⅰ(Col Ⅰ)and Collagen Ⅲ(Col Ⅲ)and remodel of extracellular matrix(ECM).Although the cell-material interaction and mechanism need more investigation,the effect of rhCol Ⅲ on damaged skin was discussed from influence on cells,reconstruction of ECM,and stimulus of small biological molecules based on current results.In conclusion,our findings provided rigorous biosafety information of rhCol Ⅲ and approved its potential in skin repair and regeneration.Although enormous efforts still need to be made to achieve successful translation from bench to clinic,the recombinant humanized collagen showed superiorities from both safety and efficacy aspects. | Jing Wang He Qiu Yang Xu Yongli Gao Peijie Tan Rui Zhao Zhanhong Liu Yajun Tang Xiangdong Zhu Chongyun Bao Hang Wang Hai Lin Xingdong Zhang | 2022 | Bioactive Materials2022，7，5： | 7 |
| 13 | Abiogenic hydrocarbons in commercial gases from the Songliao Basin,China显示文摘This paper discusses the kinetic fractionation, composition and distribution characteristics of carbon and hydrogen isotopes for various alkane gases formed in different environments, by different mecha- nisms and from different sources in nature. It is demonstrated that the biodegradation or thermode- gradation of complex high-molecule sedimentary organic material can form microbial gas or thermogenic gas. The δ 13C1 value ranges from -110‰ to -50‰ for microbial gases but from -50‰ to -35‰ (even heavier) for thermogenic gases. Controlled by the kinetic isotope fractionation, both microbial and thermogenic gases have δ 13C and δ D values characterized by normal distribution, i.e. δ 13C1< δ 13C2< δ 13C3< δ 13C4 and δ DCH4< δ DC2H6< δ DC3H8<δ DC4H10, and by a positive correlation between the δ 13C and δ D values. Simple carbonbearing molecules (CH4, CO and CO2) can form abiogenic alkane gases via polymerization in the abiological chemical process in nature, with δ 13C1 heavier than -30‰. Moreover, controlled by the kinetic isotope fractionation, abiogenic alkane gases are characterized by a reverse distribution of δ 13C values and a normal trend of δ D values, namely δ 13C1> δ 13C2> δ 13C3> δ 13C4 and δ DCH4<δ DC2H6< δ DC3H8< δ DC4H10. The δ 13C values and δ D values are negatively correlated. Natural gases from 26 commercial gas wells distributed in the Xujiaweizi and Yingshan-Miaotaizi faulted depressions in the Songliao Basin, China, show δ13C1 values ranging from -30.5‰ to -16.7‰ with a very narrow δ D range between -203‰―-196‰. These gases are characterized by a reverse distribution of δ 13C values but a normal distribution of δ D values, and a negative correlation between their δ 13C and δ D values, indicating an abiological origin. The present study has revealed that abiogenic hydrocarbons not only exist in nature but also can make significant contribution to commercial gas reserviors. It is estimated that the reserve volume of alkane gases with abiogenic characteristics in these 26 gas wells in the Songliao Basin is over 500×108 m3. The prospecting practice in the Songliao Basin has demonstrated that abiogenic alkane gases are of a promising resource, and it provides an example for the investigation of and search for abiogenic commercial natural gases worldwide. | WANG XianBin GUO ZhanQian TUO JinCai GUO HongYan LI ZhenXi ZHUO ShengGuang JIANG HongLiang ZENG LongWei ZHANG MingJie WANG LianSheng LIU ChunXue YAN Hong LI LiWu ZHOU XiaoFeng WANG YongLi YANG Hui WANG Guang | 2009 | Science China Earth Sciences2009，52，2： | 6 |
| 14 | Analysis of the ore-controlling structure of the Shihu gold deposit, Hebei Province and deep-seated ore-prospecting prediction显示文摘Under the guidance of the theory of mantle-branch structure-associated metallogenesis and on the basis of the geological characteristics, analysis of the ore-forming and ore-controlling structures, the geochemical characteristics of metallogenesis, the source of ore-forming materials, changes in the physical and chemical conditions of metallogenesis, changes in the vertical width of ore veins, and changes in gold grade of the Shihu gold deposit, the mechanism of its metallogenesis was discussed and the rules of vertical variation of ore veins were summarized in this study. It is pointed out that the orebodies under exploitation at present time should be in the middle and upper portions of gold veins in the Shihu gold mining district. Particularly on the basis of the characteristics of mantle-branch structure-associated metallogenesis, it is indicated that metallogenesis is controlled mainly by such ore-forming conditions as temperature and pressure. Deep-seated ore-forming fluids are characterized mainly by injection and precipitation. So the vein bodies in the adjacent metallogenic structures are of obvious comparability, and there would be great prospects for ore search both at depth and in the periphery of the Shihu gold deposit. Therefore, ore prospecting should be strengthened both at depth and in the peripheries. | NIU Shuyin WANG Baode SUN Aiqun CHEN Chao WANG Zili MA Baojun WANG Wenxue JIANG Xiaoping ZHAO Yongli GAO Yincang LIU Huabin QIU Jianping | 2009 | Chinese Journal Of Geochemistry2009，28，4： | 6 |
| 15 | Temporal-spatial distribution and ore-forming material source of gold,copper and silver polymetallic ore deposits in the Fuping mantle structure zone显示文摘This study was conducted following research on metallogenesis in the Zhangjiajie-Xuanhua and East Hebei mantle branch structure zones. The Fuping mantle branch structure zone is one where Au, Cu and Ag poly-metallic ore resources are concentrated in North Hebei. However, there has existed a long-standing controversy on the temporal-spatial distribution of ore resources and their ore-forming material sources. In terms of age dating and the comprehensive analysis of S, Pb, O, C and Si isotopes, it is considered that the temporal-spatial distribution of ore resources in this mantle branch structure zone is obviously controlled by the Fuping mantle branch structure. In space there is developed such a metallogenic pattern as to be Ag, Pb and Zn polymetallic ore deposits with gold appearing inside and copper appearing outside. Metallogenesis is dated mainly at Yanshanian, the ore-forming materials were derived predominantly from the deep interior of the Earth, and ore-forming fluids were derived largely from Yanshanian magmatism. | WANG Baode NIU Shuyin SUN Aiqun LIU Yaming XIE Yan JIANG Xiaoping ZHAO Yongli GAO Yincang ZHAO Fuwang | 2010 | Chinese Journal Of Geochemistry2010，29，3： | 6 |
| 16 | Parallel selection of distinct Tof5 alleles drove the adaptation of cultivated and wild soybean to high latitudes显示文摘Photoperiod responsiveness is a key factor limiting the geographic distribution of cultivated soybean and its wild ancestor.In particular,the genetic basis of the adaptation in wild soybean remains poorly understood.In this study,by combining whole-genome resequencing and genome-wide association studies we identified a novel locus,Time of Flowering 5(Tof5),which promotes flowering and enhances adaptation to high latitudes in both wild and cultivated soybean.By genomic,genetic and transgenic analyses we showed that Tof5 en-codes a homolog of Arabidopsis thaliana FRUITFULL(FUL).Importantly,further analyses suggested that different alleles of Tof5 have undergone parallel selection.The Tof5H1 allele was strongly selected by humans after the early domestication of cultivated soybean,while Tof5H2 allele was naturally selected in wild soybean,and in each case facilitating adaptation to high latitudes.Moreover,we found that the key flowering repressor E1 suppresses the transcription of Tof5 by binding to its promoter.In turn,Tof5 physically associates with the promoters of two important FLOWERING LOCUS T(FT),FT2a and FT5a,to upregulate their transcription and promote flowering under long photoperiods.Collectively,ourfindings provide insights into how wild soybean adapted to high latitudes through natural selection and indicate that cultivated soybean underwent changes in the same gene but evolved a distinct allele that was artificially selected after domestication. | Lidong Dong Qun Cheng Chao Fang Lingping Kong Hui Yang Zhihong Hou Yongli Li Haiyang Nan Yuhang Zhang Qingshan Chen Chunbao Zhang Kun Kou Tong Su Lingshuang Wang Shichen Li Haiyang Li Xiaoya Lin Yang Tang Xiaohui Zhao Sijia Lu Baohui Liu Fanjiang Kong | 2022 | Molecular Plant2022，15，2： | 5 |
| 17 | Technology status and development of mineral wool made of blast furnace slag显示文摘Under the trend of low-carbon economy,the technique of producing mineral wool insulation material from molten blast furnace slag are of great significance both to Insulation materials industry and metallurgical industry on the aspects of energy conservation and emissions reduction.This paper presents characteristics and use of mineral wool made of blast furnace slag,and also introduces mineral wool production process and key techniques.It also put forward a number of issues need to be addressed in the process.The inherent mechanism affecting the performance of the of mineral wool is analyzed.And it points out the target and future direction of R & D in Baoshan Iron and Steel in mineral wool technology field. | XIAO Yongli,LI Yongqian and LIU Yin Research Institute,Baoshan Iron & Steel Co.,Ltd.,Shanghai 201900,China | 2010 | Baosteel Technical Research2010，4，S1： | 4 |
| 18 | HIV Prevention and Health Poverty Alleviation-Liangshan Prefecture,Sichuan Province,China,2017-2020显示文摘BACKGROUND Liangshan,officially the Liangshan Yi Autonomous Prefecture,is an autonomous prefecture occupying much of the southern portion of Sichuan Province.It has been a remote and deeply impoverished area and also has the largest population of ethnic Yi people in China(1).For many years,due to geographical environment conditions,traffic conditions,and other historic restrictions,the human immunodeficiency virus(HIV)epidemic in Liangshan Prefecture has become the focus of HIV prevention and control in China since the first acquired immunodeficiency syndrome(AIDS)case was reported in this area in 1995(2-3). | Zhongfu Liu Xuefeng Tang Yufen Liu Linglin Zhang Yihui Yang Yongli Zheng Weixin Liu Chunnong Jike Hong Mai Heying Fan Gang Yu Mengjie Han George F.Gao | 2021 | China CDC weekly2021，3，48： | 4 |
| 19 | Study of the Change in Wave Velocity Ratio before and after Two Strong Earthquakes Using Airgun Source Data显示文摘Using the signals excited by the large-volume airgun source at the Binchuan transmitting seismic station from January to June,2016,arrival-time data was acquired at four stations near the epicenter of the Eryuan MS4.5 and MS4.0 earthquakes on February 8,2016,as well as the epicenter of the Yunlong MS5.0 and Eryuan MS4.6 earthquakes on May 18,2016 through the waveform cross-correlation technique.The wave velocity ratio of the four stations was calculated using the single-station method.At the same time,the b-value and the focal mechanism consistency parameters of the study area were also calculated.The results show that:(1)the wave velocity ratio of each station experienced a process of decline-recovery-fast rise before the two strong earthquakes,and a significant quasi-synchronous rapid rise occurred within 3-12 days before the earthquake;(2)the timing of the rapid rise of the wave velocity ratio of the four stations before the Yunlong MS5.0 and Eryuan MS4.6 earthquakes were related to the epicentral distance.The station which observed the earliest increase in rapid rise is the farthest one from the epicenter,and the station where the rapid rise appeared in the latest is closest to the epicenter;(3)the form of change of the wave velocity ratio before the earthquake was different between stations located at different directions in the epicenter area;(4)the b-value and the focal mechanism consistency parameter which is commonly used to characterize the stress level both showed a downward trend before the two strong earthquakes,and were consistent with the change in the wave velocity ratio.According to the preliminary analysis,the wave velocity ratio obtained by using airgun source can better reflect the change in the stress state of the underground medium. | LIU Zifeng YE Beng CHEN Jia ZHOU Qingyun WANG Guangming PENG Guanling LI Yongli | 2019 | Earthquake Research in China2019，33，2： | 4 |
| 20 | Hybrid Three-Dimensional Spiral WSe2 Plasmonic Structures for Highly Efficient Second-Order Nonlinear Parametric Processes显示文摘Two-dimensional(2D)layered materials,with large second-order nonlinear susceptibility,are currently growing as an ideal candidate for fulflling tunable nanoscale coherent light through the second-order nonlinear optical parametric processes.However,the atomic thickness of 2D layered materials leads to poor feld confnement and weak light-matter interaction at nanoscale,resulting in low nonlinear conversion efciency.Here,hybrid three-dimensional(3D)spiral WSe2 plasmonic structures are fabricated for highly efcient second harmonic generation(SHG)and sum-frequency generation(SFG)based on the enhanced light-matter interaction in hybrid plasmonic structures.Te 3D spiral WSe2,with AA lattice stacking,exhibits efcient SH radiation due to the constructive interference of nonlinear polarization between the neighboring atomic layers.Tus,extremely high external SHG conversion efciency(about 2.437×10−5)is achieved.Moreover,the ease of phase-matching condition combined with the enhanced light-matter interaction in hybrid plasmonic structure brings about efcient SHG and SFG simultaneously.Tese results would provide enlightenment for the construction of typical structures for efcient nonlinear processes. | Xianqing Lin Yingying Liu Kang Wang Xiaolong Liu Yongli Yan Yong Jun Li Jiannian Yao Yong Sheng Zhao | 2018 | Research2018，，1： | 4 |
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