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| 1 | Catalyst-Free Growth of Nanographene Films on Various Substrates显示文摘我们开发了一个新方法在各种各样的底层上直接种一致 graphene 电影,例如绝缘体,半导体,甚至金属,没有使用任何催化剂。生长用遥远的血浆改进化学药品蒸汽免职(r-PECVD ) 被执行在相对低的温度的系统,启用 graphene 电影的免职直到 4 英寸的晶片规模。扫描通道显微镜学(STM ) 证实电影由在侧面的尺寸的十纳米的 nanocrystalline graphene 粒子组成。为 nanographene 的生长机制为 PECVD 方法种的钻石类似于那,尽管有在 graphene 的情况中被形成的 sp2 碳原子而非象在钻石的 sp3 碳原子。这条生长途径简单、便宜、可伸缩,并且可能在象薄电影电阻器,煤气的传感器,电极材料,和透明传导性的电影那样的域里有潜在的应用程序。 | Lianchang Zhang Zhiwen Shi Yi Wang Rong Yang Dongxia Shi Guangyu Zhang | 2011 | Nano Research2011，4，3： | 12 |
| 2 | Additive manufacturing of Ti-6Al-4V lattice structures with high structural integrity under large compressive deformation显示文摘Additively manufactured Ti-6 Al-4 V lattice structures have found important niche applications. However, they often show insufficient compressive ductility or insufficient structural integrity. In this study,a batch of 45 octahedral Ti-6 Al-4 V lattice structures was manufactured in three different strut diameters(0.5, 1.0, 1.5 mm) by selective electron beam melting(SEBM). The influence of post-SEBM annealing on the compressive deformation characteristics of the lattice structure was investigated. The as-built Ti-6 Al-4 V lattices fragmented when the compressive strain reached 13%–23% depending on strut diameter.Annealing at 950?C(β transus temperature: 995?C) only slightly improved the compressive ductility of the lattice structures. However, annealing at 1050?C(β-annealing) fundamentally changed the compressive deformation mode of the lattice structures. The resultant compressive stress-strain curve was featured by a long smooth plateau and no facture occurred even after significant densification of the lattice structure had taken place(>50% of compressive strain). | Kun Yang Jian Wang Liang Jia Guangyu Yang Huiping Tang Yuanyuan Li | 2019 | Journal of Materials Science & Technology2019，35，2： | 12 |
| 3 | Dynamics of major air pollutants from crop residue burning in China's Mainland,2000–2014显示文摘Based on satellite image data and China's Statistical Yearbooks(2000 to 2014), we estimated the total mass of crop residue burned, and the proportion of residue burned in the field vs.indoors as domestic fuel. The total emissions of various pollutants from the burning of crop residue were estimated for 2000-2014 using the emission factor method. The results indicate that the total amount of crop residue and average burned mass were 8690.9 Tg and4914.6 Tg, respectively. The total amount of emitted pollutants including CO_2, CO, NOx,VOCs, PM_(2.5), OC(organic carbon), EC(element carbon) and TC(total carbon) were 4212.4–8440.9 Tg, 192.8–579.4 Tg, 4.8–19.4 Tg, 18.6–61.3 Tg, 18.8–49.7 Tg, 6.7–31.3 Tg, 2.3–4.7 Tg, and8.5–34.1 Tg, respectively. The emissions of pollutants released from crop residue burning were found to be spatially variable, with the burning of crop residue mainly occurring in Northeast, North and South China. In addition, pollutant emissions per unit area(10 km ×10 km) were mostly concentrated in the central and eastern regions of China. Emissions of CO_2, NOx, VOCs, OC and TC were mainly from rice straw burning, while burning of corn and wheat residues contributed most to emissions of CO, PM_(2.5) and EC. The increased ratio of PM_(2.5) emissions from crop residue burning to the total emitted from industry during the study period is attributed to the implementation of strict emissions management policies in Chinese industry. This study also provides baseline data for assessment of the regional atmospheric environment. | Quanfeng Jin Xiangqing Ma Guangyu Wang Xiajie Yang Futao Guo | 2018 | Journal of Environmental Sciences2018，30，8： | 9 |
| 4 | Sintilimab versus docetaxel as second-line treatment in advanced or metastatic squamous non-small-cell lung cancer:an open-label,randomized controlled phase 3 trial(ORIENT-3)显示文摘Background:Treatment options for Chinese patients with locally advanced or metastatic squamous-cell non-small-cell lung cancer(sqNSCLC)after failure of first-line chemotherapy are limited.This study(ORIENT-3)aimed to evaluate the efficacy and safety of sintilimab versus docetaxel as second-line treatment in patients with locally advanced or metastatic sqNSCLC.Methods:ORIENT-3 was an open-label,multicenter,randomized controlled phase 3 trial that recruited patients with stage IIIB/IIIC/IV sqNSCLC after failure with first-line platinum-based chemotherapy.Patients were randomized in a 1:1 ratio to receive either 200 mg of sintilimab or 75 mg/m^(2) of docetaxel intravenously every 3 weeks,stratified by the Eastern Cooperative Oncology Group performance status.The primary endpoint was overall survival(OS)in the full analysis set(FAS).Secondary endpoints included progression-free survival(PFS),objective response rate(ORR),disease control rate(DCR),duration of response(DoR)and safety.Results:Between August 25,2017,and November 7,2018,290 patients were randomized.For FAS,10 patients fromthe docetaxel armwere excluded.Themedian OS was 11.79(n=145;95%confidence interval[CI],10.28-15.57)months with sintilimab versus 8.25(n=135;95%CI,6.47-9.82)months with docetaxel(hazard ratio[HR]:0.74;95%CI,0.56-0.96;P=0.025).Sintilimab treatment significantly prolonged PFS(median 4.30 vs.2.79 months;HR:0.52;95%CI,0.39-0.68;P<0.001)and showed higher ORR(25.50%vs.2.20%,P<0.001)and DCR(65.50%vs.37.80%,P<0.001)than the docetaxel arm.The median DoRwas 12.45(95%CI,4.86-25.33)months in the sintilimab arm and 4.14(95%CI,1.41-7.23)months in the docetaxel arm(P=0.045).Treatment-related adverse events of grade≥3were reported in 26(18.1%)patients in the sintilimab arm and 47(36.2%)patients in the docetaxel arm.Exploratory biomarker analysis showed potential predictive values of expression levels of two transcription factors,including OVOL2(HR:0.35;P<0.001)and CTCF(HR:3.50;P<0.001),for sintilimab treatment.Conclusions:Compared with docetaxel,sintilimab significantly improved the OS,PFS,and ORR of Chinese patients with previously treated locally advanced or metastatic sqNSCLC. | Yuankai Shi Lin Wu Xinmin Yu Puyuan Xing Yan Wang Jianying Zhou Airong Wang Jianhua Shi Yi Hu Ziping Wang Guangyu An Yong Fang Sanyuan Sun Caicun Zhou Changli Wang Feng Ye Xingya Li Junye Wang Mengzhao Wang Yunpeng Liu Yanqiu Zhao Ying Yuan Jifeng Feng Zhendong Chen Jindong Shi Tao Sun Gang Wu Yongqian Shu Qisen Guo Yi Zhang Yong Song Shucai Zhang Yuan Chen Wei Li Hongrui Niu Wenwei Hu Lijun Wang Jianan Huang Yang Zhang Ying Cheng Zhengdong Wu Bo Peng Jiya Sun Christoph Mancao Yanqi Wang Luyao Sun | 2022 | Cancer Communications2022，42，12： | 8 |
| 5 | Stable isotope labelled mass spectrometry for quantification of the relative abundances for expressed proteins induced by PeaT1显示文摘The protein elicitor from the mycelium of Alternaria tenuissima has been isolated.The elicitor triggered resistance to the tobacco mosaic virus in tobacco by inducing relative oxygen species,but without causing hypersensitive necrosis.The elicitor is reported to impart resistance against Verticillium dahliae and to increase yield in cotton,but its mechanism is not yet clear.In this study,the stable isotope labelled mass spectrometry method was used to quantify the relative abundances of protein expression induced by PeaT1 in Arabidopsis.A significant difference in the relative abundances for the expression of different proteins related to metabolism,modification,regulatory,defense,stress and antioxidation was found in Arabidopsis. | LI GuangYue,YANG XiuFen,ZENG HongMei,MAO JianJun,LIU Hua,ZHANG YunHua & QIU DeWen* Key Laboratory for Biological Control of the Ministry of Agriculture,Institute of Plant Protection,Chinese Academy of Agricultural Sciences,Beijing 100081,China | 2010 | Science China(Life Sciences)2010，53，12： | 7 |
| 6 | Graphene: Nanostructure engineering and applications显示文摘 | Tingting Zhang Shuang Wu Rong Yang Guangyu Zhang | 2017 | Frontiers of physics2017，12，1： | 6 |
| 7 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 8 | Enhanced mechanical properties of 6082 aluminum alloy via SiC addition combined with squeeze casting显示文摘In order to improve mechanical properties of 6082 aluminum alloy,the SiC_(p)/Al 6082 composites were prepared by the addition of the micron-sized SiC_(p)articles combined with the squeeze casting.The effects of the SiC_(p)content and squeeze casting on the microstructure and mechanical properties of the 6082 aluminum alloy were investigated by SEM,EDS,TEM,tensile testing and hardness testing analysis methods.Research results exhibited that the SiC_(p)content and squeeze casting had a significant impact on the microstructure and mechanical properties of the 6082 aluminum alloy.The addition of the SiC_(p)refined the grain size of the 6082 aluminum alloy while caused the increase of the porosity with increasing the SiC_(p)content,especially in the permanent mold casting condition.Compared to the permanent mold casting,the squeeze casting obviously reduced pore defects,refined grain size and made the SiC_(p)distribute evenly as well as bond tightly with the Al matrix.The tensile strength,yield strength,elongation,elastic modulus and hardness of the 6082 aluminum alloy obtained with the SiC_(p)and squeeze casting were remarkably improved,and the optimal mechanical properties were obtained with a 2 wt.%SiC_(p),and they increased 10.73%,72.7%,193.9%,23.5%and 25.2%,respectively,compared to those of the6082 aluminum alloy obtained without SiC_(p)and squeeze casting.The fracture surface of the SiC_(p)/Al 6082 composites obtained with the squeeze casting was dense and exhibited a ductile fracture mode. | Wenming Jiang Junwen Zhu Guangyu Li Feng Guan Yang Yu Zitian Fan | 2021 | Journal of Materials Science & Technology2021，，29： | 6 |
| 9 | Microstructure, Microsegregation, and Mechanical Properties of Directional Solidified Mg–3.0Nd–1.5Gd Alloy显示文摘The microstructure, microsegregation, and mechanical properties of directional solidified Mg–3.0Nd–1.5Gd ternary alloys were experimentally studied. Experimental results showed that the solidification microstructure was composed of dendrite primary a(Mg) phase and interdendritic a(Mg) ? Mg12(Nd, Gd) eutectic and Mg5 Gd phase. The primary dendrite arm spacing k1 and secondary dendrite arm spacing k2 were found to be depended on the cooling rate R in the form k1= 8.0415 9 10-6R-0.279 and k2= 6.8883 9 10-6R-0.205, respectively, under the constant temperature gradient of40 K/mm and in the region of cooling rates from 0.4 to 4 K/s. The concentration profiles of Nd and Gd elements calculated by Scheil model were found to be deviated from the ones measured by EPMA to varying degrees, due to ignorance of the back diffusion of the solutes Nd and Gd within a(Mg) matrix. And microsegregation of Gd depended more on the growth rate, compared with Nd microsegregation. The directionally solidified experimental alloy exhibited higher strength than the non-directionally solidified alloy, and the tensile strength of the directionally solidified experimental alloy was improved,while the corresponding elongation decreased with the increase of growth rate. | Shaojun Liu Guangyu Yang Wanqi Jie | 2014 | Acta Metallurgica Sinica(English Letters)2014，27，6： | 6 |
| 10 | Quantitative and Functional Phosphoproteomic Analysis Reveals that Ethylene Regulates Water Transport via the C-Terminal Phosphorylation of Aquaporin PIP2;1 in Arabidopsis显示文摘乙烯参予众多的细胞的事件和生物过程的规定,包括水损失,在枯萎的叶和花花瓣期间。多样的乙烯回答可以经由在蛋白质 phosphorylation/dephosphorylation 和 ubiquitin/26S 之间的动态相互影响被调整调停 proteasome 的蛋白质降级和朊酶劈开。探讨乙烯怎么通过叉形得多的发信号的小径改变蛋白质 phosphorylation,我们执行了 15 N 稳定的同位素对待空气、对待乙烯的乙烯感觉迟钝的 Arabidopsis 双 loss-of-function 异种 ein3-1/eil1-1 上的基于标签、微分、量的 phosphoproteomics 学习。识别的 Among535 非冗余的 phosphopeptides,二和四 phosphopeptides 起来 -- 并且由乙烯的 downregulated 分别地。aquaporin PIP2 的调整乙烯的 phosphorylation; 1 断然在叶与水流动率和水损失被相关。在有量的 proteomics 的联合的基因研究, immunoblot 分析,原物胀大/缩小实验,并且长叶表示两个的转基因的植物上的水损失试金野类型并且 S280A/S283A-mutated PIP2 ; 1 在里面 Col-0 和 ein3eil1 乙烯增加浇的基因 backgroundssuggest 在由在 PIP2 的 C 终点提高 S280/S283 phosphorylation 的 Arabidopsis 房间的运输率; 1 。未知 kinase 或磷酸酶活动可以参予 EIN3/EIL1 的细胞的功能的起始的起来规定独立人士。这发现贡献我们理解那通常在植物器官的收获以后的存储期间被观察调整乙烯的叶枯萎。 | Dongjin Qing Zhu Yang Mingzhe Li Wai Shing Wong Guangyu Guo Shichang Liu Hongwei Guo Ning Li | 2016 | Molecular Plant2016，9，1： | 6 |
| 11 | Microstructure Evolution during Solidification of AZ91D Magnesium Alloy in Semisolid显示文摘熄灭方法的液体被采用在半固体学习团结形态学和 AZ91D Mg 合金的微观结构。结果显示那冷却的率在团结结构之上有重要效果。在熄灭的液体的冷却的率下面,主要 alpha 阶段由在原来的高山上属于增长第一哈谷物,或独立成核和生长。高冷却率让主要一阶段在“破布”或树突形状成长。最容易溶解的团结以分裂生长和共生生长被执行。分裂生长在谷物边界形成不平、大的贝它阶段,当共生生长形成薄片状的结构的 eutectic 时。小液体在内以象的一样的方法基本上分享原来的 a-phasesolidifies 内部小粒的液体,但是由于液相的更少的数量,最容易溶解的团结主要在分裂模式被执行。 | Wuxiao WANG Bailing JIANG Sen YUAN Wanqi JIE Guangyu YANG | 2006 | Journal of Materials Science & Technology2006，22，3： | 5 |
| 12 | In Vivo Corrosion Resistance of Ca-P Coating on AZ60 Magnesium Alloy显示文摘 | Xing Xiao Haiying Yu Qingsan Zhu Guangyu Li Yang Qu Rui Gu | 2013 | Journal of Bionic Engineering2013，10，2： | 5 |
| 13 | Quantitative response of oil sunflower yield to evapotranspiration and soil salinity with saline water irrigation显示文摘Appropriate application of water-salt-crop function model can optimize agricultural water management in regions with declining water supply,such as the Hetao district.Appropriate use of saline water is also based on the effects of irrigation water demand and water quality on crop growth quantitatively.Therefore,oil sunflower growth testing under both water and salt stress was completed from 2013 to 2014.Water salinity levels at 1.7 ds/m,4 ds/m,6 ds/m and 8 ds/m were used in the experiments.Two water deficit levels were reported,60%and 80%of the irrigation quota,which were considered moderate and mild deficit levels,respectively.All treatments were applied in planting the oil sunflower in critical growing periods,namely,floral initiation,anthesis and maturity.Linear,Cobb-Douglas,quadratic and transcendental function models were used to simulate the relative yield,evapotranspiration(ET)and electrical conductivity(EC).The predictive ability and sensitivity of each model were then evaluated.Compared with salt stress,water stress exerted a more significant effect on the oil sunflower yield;the water parameters(a1 and a3)were most sensitive in the water-salt-crop function model.Oil sunflower was most sensitive to water and salt stress during anthesis.The transcendental function generally showed a relatively high sensitivity coefficient and a relatively small statistical error.Therefore,the transcendental function is the most appropriate model for simulating and predicting the yield of oil sunflower irrigated with saline water.Applying the water-salt-crop function model in planting of oil sunflower can help in the development and utilization of saline water in the Hetao district. | He Xin Yang Peiling Ren Shumei Li Yunkai Jiang Guangyu Li Lianhao | 2016 | International Journal of Agricultural and Biological Engineering2016，9，2： | 4 |
| 14 | Frequency-multiplexing photon-counting multi-beam LiDAR显示文摘We report a frequency-multiplexing method for multi-beam photon-counting light detection and ranging(Li DAR),where only one single-pixel single-photon detector is employed to simultaneously detect the multibeam echoes.In this frequency-multiplexing multi-beam Li DAR,each beam is from an independent laser source with different repetition rates and independent phases.As a result,the photon counts from different beams could be discriminated from each other due to the strong correlation between the laser pulses and their respective echo photons.A 16-beam Li DAR system was demonstrated in three-dimensional laser imaging with 16 pulsed laser diodes at 850 nm and one single-photon detector based on a Si-avalanche photodiode.This frequencymultiplexing method can greatly reduce the number of single-photon detectors in multi-beam Li DAR systems,which may be useful for low-cost and eye-safe Li DAR applications. | TIANXIANG ZHENG GUANGYUE SHEN ZHAOHUI LI LEI YANG HAIYAN ZHANG E WU GUANG WU | 2019 | Photonics Research2019，7，12： | 4 |
| 15 | Study on meso-mechanical behavior of sand based on its 2D geometrical model显示文摘A comprehensive study on the meso-mechanical behaviors of sand with its 2D geometrical models was presented in this study.Based on the 2D geometrical models,database of sand particles,quantitative analysis on the geometrical characteristics of the studied sand particles was performed.A new clump generation algorithm based on fewer multiple overlapping circles was provided to accurately model the shape of sand particles,and was used to build the discrete element method(DEM)numerical model of the sand sample for DEM biaxial tests.The macro-and meso-mechanical behaviors of the studied sand samples were systematically analyzed.Deformation was mainly localized in a X-shaped shear zone,in which the particles experienced large displacements and rotations.Development of stress-induced anisotropy in particle and void orientations,as well as the mesoscopic fabric,was significant during the shearing process.Continuous collapse,generation,reduction,and extension of force chains occurred during the shearing process,especially after the peak stress was reached.This led to the fluctuations in the evolution of deviatoric stress and volumetric strain at macroscale,as well as the fabric anisotropy at mesoscale. | XU WenJie FENG ZeKang YANG Han LIU GuangYu | 2020 | Science China(Technological Sciences)2020，63，5： | 4 |
| 16 | Probucol attenuates ethanol‐induced liver fibrosis in rats by inhibiting oxidative stress, extracellular matrix protein accumulation and cytokine production显示文摘 | Xuesong Su Yanqiu Wang Guangyu Zhou Xu Yang Rui Yu Yan Lin Changqing Zheng | 2014 | Clin Exp Pharmacol Physiol2014，，1： | 3 |
| 17 | The influence of ^(18)F-fluorodeoxyglucose positron emission tomography/computed tomography on the N-and M-staging and subsequent clinical management of intrahepatic cholangiocarcinoma显示文摘Background:Intrahepatic cholangiocarcinoma(ICC)is a highly metastatic cancer.^(18)F-fluorodeoxyglucose positron emission tomography/computed tomography(^(18)F-FDG PET/CT)enables sensitive tumor and metastasis detection.Our aim is to evaluate the influence of pre-treatment PET/CT on the N-and M-staging and subsequent clinical management in ICC patients.Methods:Between August 2010 and August 2018,660 consecutive ICC patients,without prior anti-tumor treatments nor other malignancies,were enrolled.The diagnostic performance of PET/CT on the N-and M-staging was compared with conventional imaging,and the preoperative staging accuracy and treatment re-allocation by PET/CT were retrospectively calculated.Survival difference was compared between patients receiving PET/CT or not after propensity score matching.Results:Patients were divided into group A(n=291)and group B(n=369)according to whether PET/CT was performed.Among 291 patients with both PET/CT and conventional imaging for staging in group A,PET/CT showed significantly higher sensitivity(83.0%vs.70.5%,P=0.001),specificity(88.3%vs.74.9%,P<0.001)and accuracy(86.3%vs.73.2%,P<0.001)than conventional imaging in diagnosing regional lymph node metastasis,as well as higher sensitivity(87.8%vs.67.6%,P<0.001)and accuracy(93.5%vs.89.3%,P=0.023)in diagnosing distant metastasis.Overall,PET/CT improved the accuracy of preoperative staging from 60.1%to 71.8%(P<0.001),and modified clinical treatment strategy in 5.8%(17/291)of ICC patients,with unique roles in different tumor-node-metastasis(TNM)stages.High tumor-to-non-tumor ratio(TNR)predicted poor overall survival[hazard ratio(HR)=2.17;95%confidence interval(CI):1.49-3.15;P<0.001].Furthermore,patients performing PET/CT had longer overall survival compared with those without PET/CT(HR=0.74;95%CI:0.58-0.93;P=0.011)after propensity score matching.Conclusions:PET/CT was valuable for diagnosing regional lymph node metastasis and distant metastasis in ICC patients,and facilitated accurate tumor staging and optimal treatment allocation. | Youpei Lin Huanhuan Chong Guohe Song Chenhao Zhang Liangqing Dong Ling Aye Fei Liang Shuaixi Yang Mengsu Zeng Guangyu Ding Shu Zhang Jieyi Shi Aiwu Ke Xiaoying Wang Jian Zhou Jia Fan Qiang Gao | 2022 | Hepatobiliary Surgery and Nutrition2022，11，5： | 3 |
| 18 | Effects of dietary protein level on nutrients digestibility and reproductive performance of female mink(Neovison vison)during gestation显示文摘The objective of this study was to determine whether nutrient digestibility and reproductive performance of pregnant mink(Neovison vison) were affected by different dietary protein levels. One hundred and twenty female mink were randomly assigned to four groups, receiving diets of fresh material with different protein levels. The dietary protein levels,expressed as percentage of dry matter(DM),were 32,36, 40 and 44% respectively. These values corresponded to average 320, 360, 400 and 440 g protein/kg DM, respectively. Results were as follows. All of crude protein digestibility, nitrogen(N) intake, N retention increased along with dietary protein level increasing. Low protein level(32%) significantly reduced the above indicators(P < 0.05). DM digestibility and ether extract digestibility were not affected by dietary protein level. Results of mated females, barren females, kids per litter, live born kids per mated female, birth survival rate, and birth weight showed that mink achieved optimal reproductive performance when dietary protein level was 36%. In conclusion, dietary protein was anticipated to significantly influence some nutrients' utilization. Adopting the appropriate dietary protein level allow better reproduction performance. The most preferable reproductive performance was achieved when diet contained 275.5 g digestible protein per kg DM for female mink in gestation. | Qingkui Jiang Guangyu Li Tietao Zhang Haihua Zhang Xiuhua Gao Xiumei Xing Jiaping Zhao Fuhe Yang | 2015 | Animal Nutrition2015，，2： | 3 |
| 19 | Ca-P Conversion Coating on AZ60 Magnesium Alloy for Biomedical Application显示文摘 | CHENG Zhongji LIAN Jianshe HU Xiaoli YANG Xiaohong LI Guangyu | 2014 | Chemical Research in Chinese Universities2014，30，4： | 3 |
| 20 | Microstructure evolution,mechanical properties and diffusion behaviour of Mg-6Zn-2Gd-0.5Zr alloy during homogenization显示文摘The microstructure evolution and mechanical properties of Mg-6 Zn-2 Gd-0.5 Zr alloy during homogenization treatment were investigated. The as-cast alloy was found to be composed of dendritic primaryα-Mg matrix, α-Mg +W(Mg_3Zn_3Gd_2) eutectic along grain boundaries, and icosahedral quasicrystalline I(Mg_3Zn_6Gd) phase within α-Mg matrix. During homogenization process, α-Mg +W(Mg_3Zn_3Gd_2) eutectic and I phase gradually dissolved into a-Mg matrix, while some rod-like rare earth hydrides(GdH2)formed within α-Mg matrix. Both the tensile yield strength and the elongation showed a similar tendency as a function of homogenization temperature and holding time. The optimized homogenization parameter was determined to be 505℃ for 16 h according to the microstructure evolution. Furthermore,the diffusion kinetics equation of the solute elements derived from the Gauss model was established to predict the segregation ratio of Gd element as a function of holding time, which was proved to be effective to evaluate the homogenization effect of the experimental alloy. | Lei Xiao Guangyu Yang Yang Liu Shifeng Luo Wanqi Jie | 2018 | Journal of Materials Science & Technology2018，34，12： | 3 |
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