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| 1 | The discovery of the oldest rocks in the Kuluketage area and its geological implications显示文摘The basement rocks in the Kuluketage area are composed predominately of tonalite-trondhjemite-granodiorite rocks, and occured mainly in Xinger and Korla. U-Pb dating of TTG gneiss near Korla yielded a late Neoarchean weighted mean 207Pb/206Pb age of 2.65 Ga, which is the oldest published age for the TTG rocks in the Kuluketage area and thus suggests that Archean terrane in the area was formed in the late Neoarchean. The Korla gneiss is much younger than the TTG rocks in the northern Altyn Tagh, eastern Tarim Craton, indicating that the oldest terrane of the Tarim Craton was exposed probably in the northern Altyn Tagh. Until late Neoarchean, the Tarim continent extends to the Kuluketage area and finally had generated a relatively large uniform Archean basement within the craton. Zircon Hf isotopic analyses of the TTG gneiss give low εHf(t) values (-5 to 1) with Paleoarchean to Mesoarchean two-stage model ages (TDM2) between 3.0 and 3.3 Ga, suggesting that the basement rocks in the northern Tarim Craton were derived dominately from partial melting of Paleoarchean to Mesoarchean juvenile crustal material. The Hf model ages, therefore, indicate that no continent crust older than 3.3 Ga existed in the Kuluketage area. | LONG XiaoPing YUAN Chao SUN Min XIAO WenJiao ZHAO GuoChun ZHOU KeFa WANG YuJing HU AiQin | 2011 | Science China Earth Sciences2011，54，3： | 16 |
| 2 | Basic Characteristics,Spatial Disparity and Its Major Influencing Factors of Service Industry in China显示文摘Based on the analysis of its basic characteristics,this article investigated the disparities of Chinese service industry among the three regions(the eastern China,the western China and the middle China) and inter-provincial disparities of that in the three regions by Theil coefficient and cluster analysis.Then,major factors influencing its spatial disparity were explored by correlation analysis and regression analysis.The conclusions could be drawn as follows.1) The development of Chinese service industry experienced three phases since the 1980s:rapid growth period,slow growth period,and recovery period.From the proportion of value-added and employment,its development was obviously on the low level.From the composition of industrial structure,traditional service sectors were dominant,but modern service sectors were lagged.Moreover,its spatial disparity was distinct.2) The level of Chinese service industry was divided into five basic regional ranks:well-developed,developed,relatively-developed,underdeveloped and undevel-oped regions.As a whole,the overall structure of spatial disparity was steady in 1990-2005.But there was notable gradient disparity in the interior structure of service industry among different provinces.Furthermore,the overall disparity expanded rapidly in 1990-2005.The inter-provincial disparity of service industry in the three regions,especially in the eastern China,was bigger than the disparity among the three regions.And 3) the level of economic development,the level of urban development,the scale of market capacity,the level of transportation and telecommunication,and the abundance of human resources were major factors influencing the development of Chinese service industry. | SHEN Yuming QIU Ling REN Wangbing CAO Yi HU Dan SONG Yujing | 2009 | Chinese Geographical Science2009，19，4： | 6 |
| 3 | Oxidative capacities of size-segregated haze particles in a residential area of Beijing显示文摘The frequent haze days around the Chinese capital of Beijing in recent years have aroused great attention owing to the detrimental efects on visibility and public health. To discover the potential health efects of the haze, oxidative capacities of airborne particles collected in Beijing during haze and clear days were comparably assessed by a plasmid scission assay. Eleven water-soluble trace elements(As, Cd, Cr, Cu, Mn, Ni, Pb, V, Se, Tl, and Zn) in the size-segregated airborne particles were quantitatively analyzed by inductively coupled plasma mass spectrometry, and most of the watersoluble trace elements were found to mainly concentrate in the fine particle size of 0.56–1.0 μm. In comparison with clear days, the mass concentrations of 11 analyzed water-soluble trace elements remarkably increased during haze days, and the oxidative capacities determined by the plasmid scission assay were markedly elevated accordingly during the haze days under the same dosage of particles as for those during clear days. Water-soluble trace elements in airborne particles, such as Cu, V, and particularly Zn, were found to have significantly positive correlations with the plasmid DNA damage rates. Because Cu, V, and Zn have been considered as bioavailable elements, the evident increase of these elements during haze days may be greatly harmful to human health. | Zhenquan Sun Longyi Shao Yujing Mu Ying Hu | 2014 | Journal of Environmental Sciences2014，26，1： | 5 |
| 4 | Alterations in gut microbiota and metabolites associated with altitude-induced cardiac hypertrophy in rats during hypobaric hypoxia challenge显示文摘The gut microbiota is involved in host responses to high altitude.However,the dynamics of intestinal microecology and their association with altitude-related illness are poorly understood.Here,we used a rat model of hypobaric hypoxia challenge to mimic plateau exposure and monitored the gut microbiome,short-chain fatty acids(SCFAs),and bile acids(BAs)over 28 d.We identified weight loss,polycythemia,and pathological cardiac hypertrophy in hypoxic rats,accompanied by a large compositional shift in the gut microbiota,which is mainly driven by the bacterial families of Prevotellaceae,Porphyromonadaceae,and Streptococcaceae.The aberrant gut microbiota was characterized by increased abundance of the Parabacteroides,Alistipes,and Lactococcus genera and a larger Bacteroides to Prevotella ratio.Trans-omics analyses showed that the gut microbiome was significantly correlated with the metabolic abnormalities of SCFAs and BAs in feces,suggesting an interaction network remodeling of the microbiome-metabolome after the hypobaric hypoxia challenge.Interestingly,the transplantation of fecal microbiota significantly increased the diversity of the gut microbiota,partially inhibited the increased abundance of the Bacteroides and Alistipes genera,restored the decrease of plasma propionate,and moderately ameliorated cardiac hypertrophy in hypoxic rats.Our results provide an insight into the longitudinal changes in intestinal microecology during the hypobaric hypoxia challenge.Abnormalities in the gut microbiota and microbial metabolites contribute to the development of high-altitude heart disease in rats. | Zhiyuan Pan Yichen Hu Zongyu Huang Ni Han Yan Li Xiaomei Zhuang Jiye Yin Hui Peng Quansheng Gao Wenpeng Zhang Yong Huang Yujun Cui Yujing Bi Zhenjiang Zech Xu Ruifu Yang | 2022 | Science China(Life Sciences)2022，65，10： | 5 |
| 5 | Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis显示文摘Immunomodulatory signaling imposes tight regulations on metabolic programs within immune cells and consequentially determines immune response outcomes.Although the glucocorticoid receptor(GR)has been recently implicated in regulating the function of myeloid-derived suppressor cells(MDSCs),whether the dysregulation of GR in MDSCs is involved in immune-mediated hepatic diseases and how GR regulates the function of MDSCs in such a context remains unknown.Here,we revealed the dysregulation of GR expression in MDSCs during innate immunological hepatic injury(IMH)and found that GR regulates the function of MDSCs through modulating HIF1α-dependent glycolysis.Pharmacological modulation of GR by its agonist(dexamethasone,Dex)protects IMH mice against inflammatory injury.Mechanistically,GR signaling suppresses HIF1αand HIF1α-dependent glycolysis in MDSCs and thus promotes the immune suppressive activity of MDSCs.Our studies reveal a role of GR-HIF1αin regulating the metabolism and function of MDSCs and further implicate MDSC GR signaling as a potential therapeutic target in hepatic diseases that are driven by innate immune cell-mediated systemic inflammation. | Yun Lu Huanrong Liu Yujing Bi Hui Yang Yan Li Jian Wang Zhengguo Zhang Yu Wang Chunxiao Li Anna Jia Linian Han Ying Hu Yong Zhao Ruoning Wang Guangwei Liu | 2018 | Cellular & Molecular Immunology2018，15，6： | 4 |
| 6 | The landscape of aging显示文摘Aging is characterized by a progressive deterioration of physiological integrity,leading to impaired functional ability and ultimately increased susceptibility to death.It is a major risk factor for chronic human diseases,including cardiovascular disease,diabetes,neurological degeneration,and cancer.Therefore,the growing emphasis on “healthy aging” raises a series of important questions in life and social sciences.In recent years,there has been unprecedented progress in aging research,particularly the discovery that the rate of aging is at least partly controlled by evolutionarily conserved genetic pathways and biological processes.In an attempt to bring full-fledged understanding to both the aging process and age-associated diseases,we review the descriptive,conceptual,and interventive aspects of the landscape of aging composed of a number of layers at the cellular,tissue,organ,organ system,and organismal levels. | Yusheng Cai Wei Song Jiaming Li Ying Jing Chuqian Liang Liyuan Zhang Xia Zhang Wenhui Zhang Beibei Liu Yongpan An Jingyi Li Baixue Tang Siyu Pei Xueying Wu Yuxuan Liu Cheng-Le Zhuang Yilin Ying Xuefeng Dou Yu Chen Fu-Hui Xiao Dingfeng Li Ruici Yang Ya Zhao Yang Wang Lihui Wang Yujing Li Shuai Ma Si Wang Xiaoyuan Song Jie Ren Liang Zhang Jun Wang Weiqi Zhang Zhengwei Xie Jing Qu Jianwei Wang Yichuan Xiao Ye Tian Gelin Wang Ping Hu Jing Ye Yu Sun Zhiyong Mao Qing-Peng Kong Qiang Liu Weiguo Zou Xiao-Li Tian Zhi-Xiong Xiao Yong Liu Jun-Ping Liu Moshi Song Jing-Dong J.Han Guang-Hui Liu | 2022 | Science China(Life Sciences)2022，65，12： | 4 |
| 7 | mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration显示文摘Hair follicles(HFs)undergo cycles of degeneration(catagen),rest(telogen),and regeneration(anagen)phases.Anagen begins when the hair follicle stem cells(HFSCs)obtain sufficient activation cues to overcome suppressive signals,mainly the BMP pathway,from their niche cells.Here,we unveil that mTOR complex 1(mTORC1)signaling is activated in HFSCs,which coincides with the HFSC activation at the telogen-to-anagen transition.By using both an inducible conditional gene targeting strategy and a pharmacological inhibition method to ablate or inhibit mTOR signaling in adult skin epithelium before anagen initiation,we demonstrate that HFs that cannot respond to mTOR signaling display significantly delayed HFSC activation and extended telogen.Unexpectedly,BMP signaling activity is dramatically prolonged in mTOR signaling-deficient HFs.Through both gain-and loss-of-function studies in vitro,we show that mTORC1 signaling negatively affects BMP signaling,which serves as a main mechanism whereby mTORC1 signaling facilitates HFSC activation.Indeed,in vivo suppression of BMP by its antagonist Noggin rescues the HFSC activation defect in mTORC1-null skin.Our findings reveal a critical role for mTOR signaling in regulating stem cell activation through counterbalancing BMP-mediated repression during hair regeneration. | Zhili Deng Xiaohua Lei Xudong Zhang Huishan Zhang Shuang Liu Qi Chen Huimin Hu Xinyue Wang Lina Ning Yujing Cao Tongbiao Zhao Jiaxi Zhou Ting Chen Enkui Duan | 2015 | Journal of Molecular Cell Biology2015，7，1： | 3 |
| 8 | In-situ construction of a Mg-modified interface to guide uniform lithium deposition for stable all-solid-state batteries显示文摘Uniform lithium(Li)deposition in all-solid-state Li metal batteries is greatly influenced by the anode/electrolyte interface.Herein,a Mg-modified interface was constructed via the simple in-situ electrochemical reduction of Mg^(2+)from Mg(TFSI)_(2) in polyethylene oxide(PEO)and a Li bis(trifluoromethane)sulfoni mide(Li TFSI)formulae.As confirmed by cryogenic transmission electron microscopy,the anode/electrolyte interface exhibited hybrids consisting of crystalline Mg,Li_(2)O,and Li dots embedded in an amorphous polymer electrolyte.The crystalline Mg dots guided the uniform Li nucleation and growth,inducing a smoother anode/electrolyte interface compared with the pristine electrolyte.With 1 wt%Mg(TFSI)_(2) in the PEO-Li TFSI electrolyte,the Mg-modified electrolyte enabled the Li/Li symmetric cells with cycling performance of over 1700 and 1400 h at current densities of 0.1 and 0.2 m A cm^(-2),respectively.Moreover,the full LFP/Li cells using the novel Mg-modified electrolyte delivered a cycling lifespan of over 450 cycles with negligible capacity loss. | Tiefeng Liu Jiale Zheng Hualiang Hu Ouwei Sheng Zhijin Ju Gongxun Lu Yujing Liu Jianwei Nai Yao Wang Wenkui Zhang Xinyong Tao | 2021 | Journal of Energy Chemistry2021，30，4： | 3 |
| 9 | Large Room-Temperature Magnetoresistance in van der Waals Ferromagnet/Semiconductor Junctions显示文摘A magnetic tunnel junction(MTJ)is the core component in memory technologies,such as the magnetic random-access memory,magnetic sensors and programmable logic devices.In particular,MTJs based on twodimensional van der Waals(vd W)heterostructures offer unprecedented opportunities for low power consumption and miniaturization of spintronic devices.However,their operation at room temperature remains a challenge.Here,we report a large tunnel magnetoresistance(TMR)of up to 85%at room temperature(T=300 K)in vdW MTJs based on a thin(<10 nm)semiconductor spacer WSe_(2)layer embedded between two Fe_(3)GaTe_(2e)lectrodes with intrinsic above-room-temperature ferromagnetism.The TMR in the MTJ increases with decreasing temperature up to 164%at T=10 K.The demonstration of TMR in ultra-thin MTJs at room temperature opens a realistic and promising route for next-generation spintronic applications beyond the current state of the art. | Wenkai Zhu Shihong Xie Hailong Lin Gaojie Zhang Hao Wu Tiangui Hu Ziao Wang Xiaomin Zhang Jiahan Xu Yujing Wang Yuanhui Zheng Faguang Yan Jing Zhang Lixia Zhao Amalia Patanè Jia Zhang Haixin Chang Kaiyou Wang | 2022 | Chinese Physics Letters2022，39，12： | 2 |
| 10 | Pretreatment with probiotics Enterococcus faecium NCIMB 11181 attenuated Salmonella Typhimurium-induced gut injury through modulating intestinal microbiome and immune responses with barrier function in broiler chickens显示文摘Background:Preventing Salmonella infection and colonization in young birds is key to improving poultry gut health and reducing Salmonella contamination of poultry products and decreasing salmonellosis for human consumption(poultry meat and eggs).Probiotics can improve poultry health.The present study was conducted to investigate the impact of a probiotics,Enterococcus faecium NCIMB 11181(E.faecium NCIMB 11181)on the intestinal mucosal immune responses,microbiome and barrier function in the presence or absence of Salmonella Typhimurium(S.Typh-imurium,ST)infection.Methods:Two hundred and forty 1-day-old Salmonella-free male broiler chickens(Arbor Acres AA+)were randomly allocated to four groups with 6 replicate cages of 10 birds each.The four experimental groups were follows:(1)nega-tive control(NC),(2)S.Typhimurium,challenged positive control(PC),(3)the E.faecium NCIMB 11181-treated group(EF),(4)the E.faecium NCIMB 11181-treated and S.Typhimurium-challenged group(PEF).Results:Results indicated that,although continuous feeding E.faecium NCIMB 11181 did not obviously alleviate growth depression caused by S.Typhimurium challenge(P>0.05),E.faecium NCIMB 11181 addition significantly blocked Salmonella intestinal colonization and translocation(P<0.05).Moreover,supplemental E.faecium NCIMB 11181 to the infected chickens remarkably attenuated gut morphological structure damage and intestinal cell apoptosis induced by S.Typhimurium infection,as evidenced by increasing gut villous height and reducing intes-tinal TUNEL-positive cell numbers(P<0.05).Also,E.faecium NCIMB 11181 administration notably promoting the production of anti-Salmonella antibodies in intestinal mucosa and serum of the infected birds(P<0.05).Addition-ally,16S rRNA sequencing analysis revealed that E.faecium NCIMB 11181 supplementation ameliorated S.Typhimu-rium infection-induced gut microbial dysbiosis by enriching Lachnospiracease and Alistipes levels,and suppressing Barnesiella abundance.Predicted function analysis indicated that the functional genes of cecal microbiome involved in C5-branched dibasic acid metabolism;valine,leucine and isoleucine biosynthesis;glycerolipid metabolism and lysine biosynthesis were enriched in the infected chickens given E.faecium NCIMB 11181.While alanine,asparate and glutamate metabolism;MAPK signal pathway-yeast;ubiquine and other terpenoid-quinore biosynthesis,protein processing in endoplasmic reticulum;as well as glutathione metabolism were suppressed by E.faecium NCIMB 11181 addition.Conclusion:Collectively,our data suggested that dietary E.faecium NCIBM 11181 supplementation could ameliorate S.Typhimurium infection-induced gut injury in broiler chickens.Our findings also suggest that E.faecium NCIMB 11181 may serve as an effective non-antibiotic feed additive for improving gut health and controlling Salmonella infection in broiler chickens. | Yujing Shao Wenrui Zhen Fangshen Guo Zeqiong Hu Kaichen Zhang Linhua Kong Yuming Guo Zhong Wang | 2023 | Journal of Animal Science and Biotechnology2023，14，2： | 1 |
| 11 | Antityrosinase and antimicrobial activities of 2 - phenylethanol, 2 - phenylacetalde- hyde and 2 -phenylaeetle acid显示文摘 | ZHU YUJING ZHOU HANTAO HU YONGHUA | 2011 | Food Chemistry2011，124，1： | 1 |
| 12 | Zircon U-Pb geochronology of the Chinese continental crust: a preliminary analysis of the Elsevier science database显示文摘The amount of zircon U-Pb geochronological data for China has grown rapidly in recent years.Nearly 410,000 items of zircon U-Pb geochronological data,representing more than 7,000 relevant articles in the Elsevier Science Database,have been collected to a database in this research.Statistics on the ages and absolute errors of these collated data,yielded smallest standard errors for(206Pb/238U),(207Pb/235U),and(207Pb/206Pb)ages within respective time intervals of<1388.96 Ma,1388.96–3282.52 Ma,and>3282.52 Ma.The ages and their absolute errors were determined using three main geochronology methods,based on laser ablation inductively coupled mass spectrometer(LA-ICP-MS),sensitive high-resolution ion microprobe(SHRIMP),and secondary ion mass spectrometer(SIMS)measurements.We compared the influence of these different methods on errors for each age interval.In addition,using a Gaussian model of multi-peak fitting of zircon U-Pb age frequencies,we identified seven growth peaks in zircons from the Chinese continental crust,which are 48.60 Ma,131.49 Ma,249.91 Ma,444.27 Ma,835.95 Ma,1860.65 Ma,and 2505.54 Ma.It is clear that there are correspondences between these ages and various geological events,namely,the Wutai movement,Lvliang movement,Jinning movement,Caledonian movement,Indo-China movement,Yanshan movement,and Himalayaorogeny movement,respectively.The time and spatial distributions of these zircons correspond to distinct geological events on the Chinese continent,reflecting its crustal evolution. | Yujing Wu Xianjun Fang Sisi Liao Lizhi Xue Zhe Chen Jiangnan Yang Yamin Lu Kun Ling Shengyi Hu Shuyuan Kong Yiwei Xiong Huacheng Li Xiuqi Shang Rui Ji Xueyun Lu Biao Song Lei Zhang Jianqing Ji | 2019 | Big Earth Data2019，3，1： | 1 |
| 13 | Facile spray-drying/pyrolysis synthesis of core–shell structure graphite/silicon-porous carbon composite as a superior anode for Li-ion batteries显示文摘 | Min Li Xianhua Hou Yujing Sha Jie Wang Shejun Hu Xiang Liu Zongping Shao | 2014 | Journal of Power Sources2014，，： | 1 |
| 14 | Application of smog chambers in atmospheric process studies显示文摘Smog chamber experimental systems,which have been widely used in laboratory simulation for studying atmospheric processes,are comprehensively reviewed in this paper.The components,development history,main research topics and main achievements of smog chambers are introduced.Typical smog chambers in the world,including their volumes,wall materials,light sources and features,are summarized and compared.Key factors of smog chambers and their influences on the simulation of the atmospheric environment are discussed,including wall loss,wall emission and background pollutants.The features of next-generation smog chambers and their application prospect in future studies of the atmospheric environment are also outlined in this paper. | Biwu Chu Tianzeng Chen Yongchun Liu Qingxin Ma Yujing Mu Yonghong Wang Jinzhu Ma Peng Zhang Jun Liu Chunshan Liu Huaqiao Gui Renzhi Hu Bo Hu Xinming Wang Yuesi Wang Jianguo Liu Pinhua Xie Jianmin Chen Qian Liu Jingkun Jiang Junhua Li Kebin He Wenqing Liu Guibin Jiang Jiming Hao Hong He | 2022 | National Science Review2022，9，2： | 1 |
| 15 | Fibrovascular proliferation of retinopathy of prematurity in zone Ⅱ after initial ranibizumab treatment显示文摘This study was designed to explore the prevalence of fibrovascular proliferation not regressed in zone Ⅱ stage 3 retinopathy of prematurity(ROP)after initial intravitreal ranibizumab(IVR)injections and to explore the possible influence factors.Fifty-seven patients(108 eyes)with ROP who underwent intravitreal injection of ranibizumab between January 2013 and July 2014 participated in the retrospective study.Based on regress of fibrovascular tissue or not after initial injections of ranibizumab,eligible eyes were divided into two groups.Data was collected and analyzed with SPSS 16.0.In the study,108 eyes of 57 patients(18 females,39 males)underwent initial intravitreal injection.The mean birth weight was 1,440.0±357.7 g and the mean gestational age was 30.5±2.0 weeks.Eight of 57(14.0%)patients showed unfavorable fibrovascular proliferation after initial ranibizumab treatment within 2 weeks.Among them,11 eyes were controlled by further laser treatment and 3 eyes underwent vitrectomy.The difference of occurrence rate in hemorrhage between the two groups was significant(P<0.030),and the unfavorable group required more laser treatment(P<0.001).The incidence of unfavorable fibrovascular proliferation was relatively high,and intraocular hemorrhage was possibly associated with the progress in zone Ⅱ stage 3 ROP after initial IVR injection. | Qinrui Hu Yujing Bai Xiaoli Chen Huika Xia Lvzhen Huang Yi Chen Xiaoxin Li | 2017 | Annals of Eye Science2017，，1： | 0 |
| 16 | Plant diversity in herbal tea and its traditional knowledge in Qingtian County, Zhejiang Province, China显示文摘Herbal teas composed of locally occurring plant species have long been used as the primary form of health care in Qingtian County,Zhejiang Province,China.However,large-scale emigration overseas and an aging population threaten the conservation of traditional knowledge of these herbal teas.Traditional knowledge about the plants used for these herbal teas is not well documented in Qingtian,despite their widespread use.The aim of this study was to assess the plant-cultural diversity of plants used as herbal teas,and to point out the prospective value of herbal teas used by Qingtian people.This study was conducted using semi-structured interviews,as well as field and market surveys.Forty-three local informants were interviewed.We recorded plant resources,plant parts used,local names,and medicinal uses.Quantitative ethnobotanical indices,including cognitive salience(CS),frequency of citation(FC),index of informant consensus(Fic)and use value(UV),were calculated to analyze the level of representativeness and relative importance of plants used in herbal teas.One hundred and twenty-nine species belonging to 75 families and 113 genera were reported to be used in herbal tea,with Compositae being the richest family.Whole plants are most commonly used to make herbal teas(66.7%).In this study,informants reported that 92.2%of plant species used in herbal teas are wild.The most utilized herbal preparation form is dry/fresh.Informants reported that herbal teas are used to treat 31 ailments.Our results show that the highest representativeness,based on CS and FC,was recorded for species Actinidia eriantha.Based on UV,the top five most used species are Goodyera schlechtendaliana,Plantago asiatica,Prunella vulgaris,Lophatherum gracile and Leonurus japonicus.The highest Fic was cited for dental medicine.This study helps document the status of current herbal teas in Qingtian.The use value and traditional knowledge of herbal teas have provided basic data for further research focused on bioactivity studies and sustainable utilization of the most important species. | Yujing Liu Renchuan Hu Songsong Shen Zheng Zhang Jing Zhang Xiaoling Song Sheng Qiang | 2020 | Plant Diversity2020，42，6： | 0 |
| 17 | CATase-immobilized hydrogel platform molded by photo-enzyme coupling polymerization for effectively preventing postoperative abdominal adhesion显示文摘Redox homeostasis,which is regulated by enzymes acting as regulatory valves,is crucial for maintaining the proper functioning of biomolecules and a stable microenvironment for physiological processes by modulating the homeostasis of reactive oxygen species(ROS).Antioxidant enzymes in biocatalysis are used in the prevention or treatment of oxidative stress-related disease by counteracting the harmful effects of ROS.However,designing a system that can efficiently immobilize antioxidant enzymes with high catalytic activity and stability is still challenging.Bioinspired by photo-biocatalysis,a novel and effective catalase(CATase)-immobilized hydrogel platform has been developed by the proposed photo-enzymatic coupled radical polymerization strategy of the visible light coupling with the porphyrin-centered CATase.The higher catalytic stability and activity can therefore be achieved due to the preferential polymerization of CATase-immobilized hydrogel platform with a favorable three-dimensional network of enhanced coupling efficacy between light and enzymes.The mechanisms of free radical-initiated polymerization as well as the antioxidant cycle in the photo-CATase coupling system have been explored.Intriguingly,the CATase-immobilized hydrogel platform affords an unprecedented antioxidant ability to scavenge ROS and provide an effective cellular protection mechanism against external oxidative stress.Additionally,the CATase-immobilized hydrogel platform can effectively prevent peritoneal adhesion by reducing the expression of inflammatory cytokines.Therefore,the novel CATase-immobilized hydrogel platform is a potential candidate for physical barriers that effectively prevent postoperative adhesion formation,offering a new anti-adhesion strategy for clinical applications. | Min Hu Mingyue Shi Xia Wang Yujing Tang Dingze Zhou Kai Pan Qigang Wang | 2023 | Science China Chemistry2023，66，9： | 0 |
| 18 | Simulation of 3D moving sound显示文摘A novel approach to the simulation of 3D sound movement by combining wellknown physical and biophysical cues into a discrete synthesis system is introduced. Physical cues include both the dependence of intensity on distance from the sound source and the Doppler effect. Biophysical features include the direction-dependent transfer functions imposed by a listener’s head and ears and interaural time cues. Our technique requires very little disk storage since it relies on Iow-dimensional functional models that relate cue values to arbitrary locations in a virtual space. The system has been implemented on a modern workstation and can synthesize in quasi-real-time movements of arbitrary sound sources and trajectories that are delivered over | QIU Yujing Jenison R L Hu Y H Reate R A Brugge J F (Departments of Electrical and Computer Engineering, Psychology, Physiology and Waisman Center, University of Wisconsin-Madison USA WI 53705) | 1999 | Chinese Journal of Acoustics1999，18，2： | 0 |
| 19 | Dysplasia of male organs induces apomixis in Malus crabapples显示文摘Apomixis has high value in fruit crop propagation and breeding applications,particularly for the transgenerational fixation of heterosis.In this study,we found that flowers of the triploid Malus cultivar'Royalty'that were bagged after emasculation(EB)and pollinated with pollen from the diploid cultivar'Flame'(EFB)produced high fruit set and increased seed numbers per fruit.The offspring exhibited superior growth vigour compared to those of the diploid sister cultivar'Flame'.The fruit setting rate for'Royalty'EFB was 98.44%,which was much higher than the fruit setting rate for'Royalty'BA(Bagging without emasculation)at 19.7%.The fruit setting rate for'Royalty'EB was 47.46%compared to 19.7%for'Royalty'BA.Furthermore,offspring derived from either'Royalty'EB or EFB exhibited superior growth vigour compared to those of the diploid'Flame'.These results suggested that'Royalty'exhibits facultative apomixis and has strong sexual reproductive ability under the stimulation of foreign pollen.Additionally,'Royalty'anthers did not dehisce after flowering and had malformed pollen grains and a low pollen germination rate.Therefore,we proposed that dysplasia of the male organ could be an important driver factor of apomixis in'Royalty'.Our study provides new insight into the mechanism of apomixis in Malus crabapples. | Yujing Hu Yanfen Lu Linke Chao Zhen Wang Yufen Bu Jie Zhang Wenhe Wang Yuncong Yao | 2021 | Ornamental Plant Research2021，1，1： | 0 |
| 20 | Crustal evolution events in the Chinese continent: evidence from a zircon U-Pb database显示文摘The zircon U-Pb chronology database provides a good opportunity to obtain important zircon growth peak periods in the Earth’s history so as to study the origin and evolution of the crust.It should be noted that research preference affects the objectivity of zircon sampling,leading to hot data in the database and age statistics.To evaluate the influence of hot data on statistical results,the W and Y indexes are introduced.Using a Gaussian model of multipeak fitting of zircon U-Pb age frequencies,we identify seven major growth peaks in zircons from the Chinese continental crust,which are 2498.95,1855.82,828.88,444.29,249.46,131.96,and 58.21 Ma.Due to differences in the time scales of zircon growth peaks,these peaks can be divided into two categories:first-order zircon growth peaks(Ⅰ)and second-order zircon growth peaks(Ⅱ),which represent longer and shorter time scales,perhaps due to different kinds of geological dynamics,respectively.In addition,there are clear correspondences between these ages and various geological events recognized by most scholars,namely,the Wutai orogeny,Lvliang orogeny,Jinning orogeny,Caledonian orogeny,Indosinian orogeny,Yanshanian orogeny,and Himalayan orogeny,respectively. | Yujing Wu Xianjun Fang Sisi Liao Lizhi Xue Zhe Chen Jiangnan Yang Yamin Lu Kun Ling Shengyi Hu Shuyuan Kong Yiwei Xiong Huacheng Li Xiuqi Shang Rui Ji Xueyun Lu Biao Song Lei Zhang Jianqing Ji | 2020 | International Journal of Digital Earth2020，13，12： | 0 |
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