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| 1 | One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system显示文摘 | Haifeng Wan Chunjing Feng Fei Teng Shihua Yang Baoyang Hu Yuyu Niu Andy Peng Xiang Weizhen Fang Weizhi Ji Wei Li Xiaoyang Zhao Qi Zhou | 2015 | Cell Research2015，25，2： | 39 |
| 2 | Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination显示文摘 | Yiqiang Cui Yuyu Niu Jiankui Zhou Yongchang Chen Yiwei Cheng Shangang Li Zongyong Ai Chu Chu Hong Wang Bo Zheng Xuejin Chen Jiahao Sha Xuejiang Guo Xingxu Huang Weizhi Ji | 2018 | Cell Research2018，28，3： | 13 |
| 3 | Myocardin-Related Transcription Factor A Mediates OxLDL-Induced Endothelial Injury显示文摘 | Fang, Fei Yang, Yuyu Yuan, Zhibin Gao, Yuqi Zhou, Jiliang Chen, Qi Xu, Yong | 2011 | 南京医科大学学报(自然科学版)2011，31，6： | 12 |
| 4 | Germline acquisition of Cas9/RNA-mediated gene modifications in monkeys显示文摘 | Yongchang Chen Yiqiang Cui Bin Shen Yuyu Niu Xiaoyang Zhao Lei Wang Jianying Wang Wei Li Qi Zhou Weizhi Ji Jiahao Sha Xingxu Huang | 2015 | Cell Research2015，25，2： | 8 |
| 5 | Butterfly distribution of Earth's radiation belt relativistic electrons induced by dayside chorus显示文摘Previous theoretical studies have shown that dayside chorus can produce butterfly distribution of energetic electrons in the Earth's radiation belts by preferentially accelerating medium pitch angle electrons, but this requires the further confirmation from highresolution satellite observation. Here, we report correlated Van Allen Probes data on wave and particle during the 11-13 April,2014 geomagnetic storm. We find that a butterfly pitch angle distribution of relativistic electrons is formed around the location L = 4.52, corresponding to the presence of enhanced dayside chorus. Using a Gaussian distribution fit to the observed chorus spectra, we calculate the bounce-averaged diffusion rates and solve two-dimensional Fokker-Planck equation. Numerical results demonstrate that acceleration by dayside chorus can yield the electron flux evolution both in the energy and butterfly pitch angle distribution comparable to the observation, providing a further evidence for the formation of butterfly distribution of relativistic electrons driven by very low frequency(VLF) plasma waves. | jin yuyue yang chang he yihua liu si zhou qinghua xiao fuliang | 2018 | Science China(Technological Sciences)2018，61，2： | 5 |
| 6 | Incidence and clinical characteristics of inflammatory bowel disease in a developed region of G uangdong P rovince, C hina: A prospective population‐based study显示文摘 | Zhirong Zeng Zhenhua Zhu Yuyu Yang Weishan Ruan Xiabiao Peng Yuhuan Su Lin Peng Jinquan Chen Quan Yin Chao Zhao Haihua Zhou Shuai Yuan Yuantao Hao Jiaming Qian Siew Chien Ng Minhu Chen Pinjin Hu | 2013 | J Gastroenterol Hepatol2013，，7： | 5 |
| 7 | Principle and application of three-band gradient difference vegetation index显示文摘Vegetation index is a simple, effective and experiential measurement of terrestrial vegetation activity, and plays a very important role in qualitative and quantitative remote sensing. Aiming at shortages of current vegetation indices, and starting from the analysis of vegetation spectral characteristics, we put forward a new vegetation index, the three-band gradient difference vegetation index (TGDVI), and established algorithms to inverse crown cover fraction and leaf area index (LAI) from it. Theoretical analysis and model simulation show that TGDVI has high saturation point and the ability to remove the influence of background to some degree, and the explicit functional relation with crown cover fraction and LAI can be established. Moreover, study shows that TGDVI also has the ability to partly remove the influence of thin cloud. Experiment in the Shunyi District, Beijing, China shows that reasonable result can be reached using the vegetation index to retrieve LAI. We also theoretically analyzed the reason why the normalized difference vegetation index (NDVI) owns the low saturation point, and show that it is determined by the definition of NDVI and the characteristic of vegetation spectra, and is unavoidable to some degree. Meanwhile, through model simulation, we also indicate that the relationship between simple ratio vegetation index (SR) and LAI closes to a piecewise linear one instead of a linear one, which is mainly caused by the influence of background and different change rates of reflectance in red and infrared bands with LAI increasing. | TANG Shihao, ZHU Qijiang, WANG Jindi, ZHOU Yuyu & ZHAO Feng Research Center for Remote Sensing and GIS, Department of Geography, Beijing Normal University, Beijing 100875, China National Satellite Meteorological Center, China Meteorological Administration, Beijing 100081, China | 2005 | Science China Earth Sciences2005，48，2： | 4 |
| 8 | Parathyroid hormone increases alveolar bone homoeostasis during orthodontic tooth movement in rats with periodontitis via crosstalk between STAT3 and β-catenin显示文摘Periodontitis patients are at risk of alveolar bone loss during orthodontic treatment.The aim of this study was to investigate whether intermittent parathyroid hormone(1–34)treatment(iPTH)could reduce alveolar bone loss during orthodontic tooth movement(OTM)in individuals with periodontitis and the underlying mechanism.A rat model of OTM in the context of periodontitis was established and alveolar bone loss was observed.The control,iPTH and iPTH+stattic groups received injections of vehicle,PTH and vehicle,or PTH and the signal transducer and activator of transcription 3(STAT3)inhibitor stattic,respectively.iPTH prevented alveolar bone loss by enhancing osteogenesis and suppressing bone resorption in the alveolar bone during OTM in rats with periodontitis.This effect of iPTH was along with STAT3 activation and reduced by a local injection of stattic.iPTH promoted osteoblastic differentiation and might further regulate the Wnt/β-catenin pathway in a STAT3-dependent manner.The findings of this study suggest that iPTH might reduce alveolar bone loss during OTM in rats with periodontitis through STAT3/β-catenin crosstalk. | Cheng Zhang Tiancheng Li Chenchen Zhou Li Huang Yuyu Li Han Wang Peipei Duan Shujuan Zou Li Mei | 2020 | International Journal of Oral Science2020，12，4： | 4 |
| 9 | Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos显示文摘 | Yuyu Niu Bin Shen Yiqiang Cui Yongchang Chen Jianying Wang Lei Wang Yu Kang Xiaoyang Zhao Wei Si Wei Li Andy Peng Xiang Jiankui Zhou Xuejiang Guo Ye Bi Chenyang Si Bian Hu Guoying Dong Hong Wang Zuomin Zhou Tianqing Li Tao Tan Xiuqiong Pu Fang Wang Shaohu | 2014 | Cell2014，，： | 3 |
| 10 | Warm dense matter research at HIAF显示文摘The research activities on warm dense matter driven by intense heavy ion beams at the new project High Intensity heavy-ion AcceleratorFacility (HIAF) are presented. The ion beam parameters and the simulated accessible state of matter at HIAF are introduced, respectively. Theprogresses of the developed diagnostics for warm dense matter research including high energy electron radiography, multiple-channel pyrometer,in-situ energy loss and charge state of ion detector are briefly introduced. | Rui Cheng Yu Lei Xianming Zhou Yuyu Wang Yanhong Chen Yongtao Zhao Jieru Ren Lina Sheng Jiancheng Yang Zimin Zhang Yingchao Du Wei Gai Xinwen Ma Guoqing Xiao | 2018 | Matter and Radiation at Extremes2018，3，2： | 2 |
| 11 | High resolution fossil thel combustion CO^2 emission fluxes for the United States显示文摘 | GUIkNEY K R MENDOZA D L ZHOU Yuyu | 2009 | Environmental Science and Technology2009，14，43： | 1 |
| 12 | Estimation of the relationship between remotely sensed anthropogenic heat discharge and building energy use显示文摘 | Yuyu Zhou Qihao Weng Kevin R. Gurney Yanmin Shuai Xuefei Hu | 2011 | ISPRS Journal of Photogrammetry and Remote Sensing2011，，： | 1 |
| 13 | The Long-term Health and Economic Consequences of the 1959-1961 Famine in China显示文摘 | Chen Yuyu Li-An Zhou | 2007 | Journal of Health Economics2007，，26： | 1 |
| 14 | Quantifying the response of surface urban heat island to urbanization using the annual temperature cycle model显示文摘Urban heat island(UHI),driving by urbanization,plays an important role in urban sustainability under climate change.However,the quantification of UHI’s response to urbanization is still challenging due to the lack of robust and continuous temperature and urbanization datasets and reliable quantification methods.This study proposed a framework to quantify the response of surface UHI(SUHI)to urban expansion using the annual temperate cycle model.We built a continuous annual SUHI series at the buffer level from 2003 to 2018 in the Jing-Jin-Ji region of China using MODIS land surface temperature and imperviousness derived from Landsat.We then investigated the spatiotemporal dynamic of SUHI under urban expansion and examined the underlying mechanism.Spatially,the largest SUHI interannual variations occurred in suburban areas compared to the urban center and rural areas.Temporally,the increase in SUHI under urban expansion was more significant in daytime compare to nighttime.We found that the seasonal variation of SUHI was largely affected by the seasonal variations of vegetation in rural areas and the interannual variation was mainly attributed to urban expansion in urban areas.Additionally,urban greening led to the decrease in summer daytime SHUI in central urban areas.These findings deepen the understanding of the long-term spatiotemporal dynamic of UHI and the quantitative relationship between UHI and urban expansion,providing a scientific basis for prediction and mitigation of UHI. | Huidong Li Yuyu Zhou Gensuo Jia Kaiguang Zhao Jinwei Dong | 2022 | Geoscience Frontiers2022，13，1： | 1 |
| 15 | The Long-Term Health and Economic Consequences of the 1959-1961 Famine in China显示文摘 | Chen Yuyu Li-An Zhou | | 0，，04： | 1 |
| 16 | Determination of trace amounts of lead, arsenic, nickel and cobalt in high-purity iron oxide pigment by inductively coupled plasma atomic emission spectrometry after iron matrix removal with extractant-contained resin 显示文摘 | Xu Yuyu Zhou Jianfeng Wang Guoxin et el | 2007 | Analytica Chimica Acta2007，584，1： | 1 |
| 17 | Re-understanding of land surface albedo and related terms in satellite-based retrievals显示文摘Land surface albedo is a critical variable in determining surface energy balance,and regulating climate and ecosystem processes through feedback mechanisms.Therefore,climatic modelers and radiative monitoring require accurate estimates of land surface albedo.With the instrument development,algorithm upgrade,spectral-band-adjustment in wavelength center or band width,and the increasing distinct requirement from diversified communities,various albedo terms have been generated in related satellite-based products.The lack of understanding on the divergence of these terminologies can introduce potential considerable errors in the subsequent applications,or an elevated probability to invert the deduced conclusion.We surveyed the basic concepts of reflectance quantities,retrieval strategies,and models developed since the 1970s,and discuss both strength and opportunity for improvements on land surface albedo extraction,and product generation.In addition,we exemplified the difference of albedo terms using the daily MODIS product(MCD43A)to emphasize the potential risk of the ambiguous usage,over typical IGBP land covers in Northern Kazakhstan.Our investigation shows that relative differences among various albedo terms can reach up to 181%and 50%,while 0.266 and 0.118 of absolute variance respectively in the narrow and broad-band surface albedo,which illuminated cautions against the ambiguous understanding of albedo terminologies or erroneous usage of albedo products. | Yanmin Shuai Latipa Tuerhanjiang Congying Shao Feng Gao Yuyu Zhou Donghui Xie Tao Liu Ji Liang Nan Chu | 2020 | Big Earth Data2020，4，1： | 1 |
| 18 | Examining Health of Wetlands with Multiple Ecosystem Services as Targets in China’s Coastal Regions显示文摘Coastal zones are key interconnectors of terrestrial and marine ecosystems.Due to the degradation and fragmentation of coastal wetlands,there is an urgent need to develop assessment methodology to compare the health of wetland ecosystems at different spatial scales.This will help efficiently develop and implement protections using easy-to-access ecosystem health data.This study aims to understand the spatial distribution of coastal and inland wetland health for China’s coastal regions.A Wetland Health Index(WHI)was developed to provide a basis for policy and decision making.Four utilization models—Long Term Model,Open Model,Nature Reserve Model,and Protected and Economic Model—were defined in the context of China’s coastal regions to specifically examine wetland health.Results show that the average WHI score was 63.6 with the range of 44.8–84.3 for 35 National Nature Reserves(NNRs),and the southern NNRs generally performed better than the northern NNRs.The wetlands in the southern provinces/municipalities are relatively healthier than their northern counterparts.The competent authority has slight influence on WHI scores but duration of conservation establishment does not show a clear correlation.With increasing economic activity,the differences in health conditions(WHI scores)of China’s coastal regions also increase.Gross Domestic Product(GDP)or economic intensification does not relate to WHI scores.Appropriate trade-offs between wetland management and economic development could contribute to improve health conditions,conservation and utilization of coastal and inland wetlands. | ZHOU Yangming DOU Yuehan YU Xiubo ZHANG Li HUANG Chong WANG Yuyu LI Xiaowei LI He JIA Yifei BAKKER Martha CARSJENS Gerrit Jan ZHOU Yan DUAN Houlang | 2020 | Chinese Geographical Science2020，30，4： | 1 |
| 19 | Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos显示文摘 | Yuyu Niu Bin Shen Yiqiang Cui Yongchang Chen Jianying Wang Lei Wang Yu Kang Xiaoyang Zhao Wei Si Wei Li Andy Peng Xiang Jiankui Zhou Xuejiang Guo Ye Bi Chenyang Si Bian Hu Guoying Dong Hong Wang Zuomin Zhou Tianqing Li Tao Tan Xiuqiong Pu Fang Wang Shaohu | 2014 | Cell2014，，： | 1 |
| 20 | An effective resolution algorithm for the two di- mensional bin-packing problem显示文摘 | Yuyu Zhou Yunqing Rao Chaoyong Zhang | 2011 | Materials Sci- ence and Engineering2011，29，24： | 1 |
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