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| 1 | Application of artificial neural networks in global climate change and ecological research:An overview显示文摘Fields that employ artificial neural networks(ANNs)have developed and expanded continuously in recent years with the ongoing development of computer technology and artificial intelligence.ANN has been adopted widely and put into practice by research-ers in light of increasing concerns over ecological issues such as global warming,frequent El Nio-Southern Oscillation(ENSO)events,and atmospheric circulation anomalies.Limitations exist and there is a potential risk for misuse in that ANN model pa-rameters require typically higher overall sensitivity,and the chosen network structure is generally more dependent upon individ-ual experience.ANNs,however,are relatively accurate when used for short-term predictions;despite global climate change re-search favoring the effects of interactions as the basis of study and the preference for long-term experimental research.ANNs remain a better choice than many traditional methods when dealing with nonlinear problems,and possesses great potential for the study of global climate change and ecological issues.ANNs can resolve problems that other methods cannot.This is especially true for situations in which measurements are difficult to conduct or when only incomplete data are available.It is anticipated that ANNs will be widely adopted and then further developed for global climate change and ecological research. | LIU ZeLin PENG ChangHui XIANG WenHua TIAN DaLun DENG XiangWen ZHAO MeiFang | 2010 | Chinese Science Bulletin2010，55，34： | 9 |
| 2 | Adsorption of 2-mercaptobenzothiazole from aqueous solution by organo-bentonite显示文摘The adsorption behavior of 2-mercaptobenzothiazole onto organo-bentonite was investigated.Natural bentonite from Gaozhou in Guangdong Province,China was collected.Organo-bentonite was prepared by intercalation of cetyltrimethyl ammonium bromide into the natural bentonite.The physicochemical properties of the prepared organo-bentonite were characterized by X-ray diffraction,N2 adsorption-desorption isotherm and Fourier transform infrared spectroscopy.The results showed that montmorillonite is the main component of the natural bentonite.The basal spacing of the natural bentonite is 1.47 nm,which increased to 1.98 nm on intercalation with cetyltrimethyl ammonium bromide.Moreover,both the surface area and pore volume increased with intercalation.Clear CH2 stretching(3000-2800 cm-1) and scissoring(1480-1450 cm-1) modes of the intercalated surfactants were observed for organobentonite.Compared with the pseudo first-order kinetic model,the pseudo second-order kinetic model is more suitable to describe the adsorption kinetics of 2-mercaptobenzothiazole onto organo-bentonite.The adsorption capacity of 2-mercaptobenzothiazole onto organo-bentonite increased with increasing initial concentration of 2-mercaptobenzothiazole,but decreased with increasing adsorbent dosage.The adsorption isotherm of 2-mercaptobenzothiazole onto organo-bentonite fits well with the Langmuir model.The maximum adsorption capacity of organo-bentonite for 2-mercaptobenzothiazole was 33.61 mg/g,indicating that organo-bentonite is a promising adsorbent for 2-mercaptobenzothiazole. | Ping Jing Meifang Hou Ping Zhao Xiaoyan Tang Hongfu Wan | 2013 | Journal of Environmental Sciences2013，25，6： | 6 |
| 3 | Magnetic resonance study of the structure and function of the hippocampus and amygdala in patients with depression显示文摘 | Li Yuefeng Yan Jinchuan Wang Dongqing Sun Meifang Zhu Yan Zhu Xiaolan Jiang Ping Yin Ruigen Zhao Liang | 2014 | Chinese Medical Journal2014，，20： | 6 |
| 4 | The role of β18-β19 loop structure in insecticidal activity of Cry1Ac toxin from Bacillus thuringiensis显示文摘The β18-β19 loop in domain III of Cry1Ac toxin is unique among Bacillus thuringiensis Cry proteins. In this study, the role of the loop structure in insecticidal activity of Cry1Ac toxin was investigated. Alanine scanning mutations within the loop were initially generated and most mutants were over-expressed and reduced toxicity at different degrees, except mutant N546A that showed almost 2 times enhanced toxicity against Helicoverpa armigera larvae. Further mutagenic analysis of N546 revealed that a charged amino acid in this position would cause very unfavorable influence on insecticidal activity. In addition, the deletion of N546 led to protein instability because of destruction of the loop integrity. Besides, mutant W544F was much more toxic than W544Y, indicating that hydrophobic nature of the position was important for maintaining the stability and activity of Cry1Ac protein. These findings are the first biological evidence for a structural function of β18-β19 loop in insecticidal activity of the Cry1Ac toxin. | XIA LiQiu WANG FaXiang DING XueZhi ZHAO XinMin FU ZuJiao QUAN MeiFang YU ZiNiu | 2008 | Chinese Science Bulletin2008，53，20： | 4 |
| 5 | The relationships among aerosol optical depth, ice, phytoplankton and dimethylsulfide and the implication for future climate in the Greenland Sea显示文摘The sea-to-air flux of dimethylsulphide(DMS) is one of the major sources of marine biogenic aerosol, and can have an important radiative impact on climate, especially in the Arctic Ocean. Satellite-derived aerosol optical depth(AOD) is used as a proxy for aerosol burden which is dominated by biogenic aerosol during summer and autumn. The spring sea ice melt period is a strong source of aerosol precursors in the Arctic. However, high aerosol levels in early spring are likely related to advection of continental pollution from the south(Arctic haze).Higher AOD was generally registered in the southern part of the study region. Sea ice concentration(SIC) and AOD were positively correlated, while cloud cover(CLD) and AOD were negative correlation. The seasonal peaks of SIC and CLD were both one month ahead of the peak in AOD. There is a strong positive correlation between AOD and SIC. Melting ice is positively correlated with chlorophyll a(CHL) almost through March to September,but negatively correlated with AOD in spring and early summer. Elevated spring and early summer AOD most likely were influenced by combination of melting ice and higher spring wind in the region. The peak of DMS flux occurred in spring due to the elevated spring wind and more melting ice. DMS concentration and AOD were positively correlated with melting ice from March to May. Elevated AOD in early autumn was likely related to the emission of biogenic aerosols associated with phytoplankton synthesis of DMS. The DMS flux would increase more than triple by 2100 in the Greenland Sea. The significant increase of biogenic aerosols could offset the warming in the Greenland Sea. | QU Bo GABRIC Albert J. ZHAO Li SUN Wenjing LI Hehe GU Peijuan JIANG Limei ZENG Meifang | 2018 | Acta Oceanologica Sinica2018，37，5： | 4 |
| 6 | Psychometric properties of the Spence Children’s Anxiety Scale (SCAS) in Mainland Chinese children and adolescents显示文摘 | Jinxia Zhao Xiaopei Xing Meifang Wang | 2012 | Journal of Anxiety Disorders2012，，7： | 2 |
| 7 | Influence of acetone on nanostructure and electrochemical properties of interfacial synthesized polyaniline nanofibers显示文摘The growth of polyaniline(PANI) nano fi bers through interfacial polymerization can be well controlled by adding a small amount of acetone in the water/chloroform system. It was found that the polymerization rate became slower in the presence of acetone, yielding PANI nano fi bers with larger aspect ratios. The in fl uences of the acetone addition on the morphology, microstructure and properties of as-prepared PANI nano fi bers were studied by scanning electron microscope(FE-SEM), ultraviolet–visible spectra(UV–vis), Fourier transform infrared(FT-IR) and Raman spectroscopy, X-ray diffraction(XRD), thermogravity analysis(TGA), and electrical and electrochemical measurements. The experimental results showed that PANI nano fi bers prepared by using ammonium persulfate(APS) as an oxidant with acetone exhibited slower growth, the larger ratio of length to diameter, and higher crystallinity(2θ=6℃, 19℃, 26℃) than that without acetone, meanwhile remained larger yield of 11.23% and higher conductivity 1.8*10-2S/cm compared with that obtained by replacing APS with Fe Cl3. More importantly, these PANI nano fi bers exhibited better electrochemical behaviors, which bene fi tted from their high crystallinity and good conductivity. | Jianyun Zhao Zongyi Qin Tao Li Zhuozhan Li Zhe Zhou Meifang Zhu | 2015 | Progress in Natural Science:Materials International2015，25，4： | 2 |
| 8 | Integrated dynamic wet spinning of core-sheath hydrogel fibers for optical-to-brain/tissue communications显示文摘Hydrogel optical light-guides have received substantial interest for applications such as deep-tissue biosensors,optogenetic stimulation and photomedicine due to their biocompatibility,(micro)structure control and tissue-like Young’s modulus.However,despite recent developments,large-scale fabrication with a continuous synthetic methodology,which could produce core-sheath hydrogel fibers with the desired optical and mechanical properties suitable for deep-tissue applications,has yet to be achieved.In this study,we report a versatile concept of integrated light-triggered dynamic wet spinning capable of continuously producing core-sheath hydrogel optical fibers with tunable fiber diameters,and mechanical and optical propagation properties.Furthermore,this concept also exhibited versatility for various kinds of core-sheath functional fibers.The wet spinning synthetic procedure and fabrication process were optimized with the rational design of the core/sheath material interface compatibility[core=poly(ethylene glycol diacrylate-co-acrylamide);sheath=Ca-alginate],optical transparency,refractive index and spinning solution viscosity.The resulting hydrogel optical fibers exhibited desirable low optical attenuation(0.18±0.01 d B cm^(-1) with 650 nm laser light),excellent biocompatibility and tissue-like Young’s modulus(<2.60 MPa).The optical waveguide hydrogel fibers were successfully employed for deep-tissue cancer therapy and brain optogenetic stimulation,confirming that they could serve as an efficient versatile tool for diverse deep-tissue therapy and brain optogenetic applications. | Guoyin Chen Gang Wang Xinrong Tan Kai Hou Qingshuo Meng Peng Zhao Shun Wang Jiayi Zhang Zhan Zhou Tao Chen Yanhua Cheng D Benjamin S.Hsiao Elsa Reichmanis Meifang Zhu | 2021 | National Science Review2021，8，9： | 2 |
| 9 | The trend in newly diagnosed Crohn’s disease and extraintestinal manifestations of Crohn’s disease in central China: a retrospective study of a single center显示文摘 | Fengming Yi Min Chen Meifang Huang Jin Li Junzhang Zhao Lixia Li Bing Xia | 2012 | European Journal of Gastroenterology & Hepatology2012，，12： | 1 |
| 10 | Application of TRIPLEX model for predicting Cunninghamia lanceolata and Pinus massoniana forest stand production in Hunan province, southern China 显示文摘 | Meifang Zhao Wenhua Xiang Xiangwen Deng | 2013 | Ecological Modelling2013，250，： | 1 |
| 11 | Morphology-dependent capacitive properties of three nanostructured polyanilines through interfacial polymerization in various acidic media显示文摘 | Tao Li Zongyi Qin Banglei Liang Fei Tian Jianyun Zhao Na Liu Meifang Zhu | 2015 | Electrochimica Acta2015，，： | 1 |
| 12 | Resistin and insulin resistance in hepatocytes: Resistin disturbs glycogen metabolism at the protein level显示文摘 | Yang Yang Meifang Xiao Yiqing Mao Hui Li Shuyong Zhao Yi Gu Rong Wang Jianqiang Yu Xuemei Zhang David M. Irwin Gang Niu Huanran Tan | 2008 | Biomedicine & Pharmacotherapy2008，，5： | 1 |
| 13 | 杉木叶片性状不支持广为接受的通量性状网络假说显示文摘“高叶脉密度-更快生长和更高的生产力”模型和假说认为高叶脉密度能促进更高的碳和水的耦合效率,暗示了个体的快速生长和高林分生产力,这些假说被研究者广泛关注和认同。然而,这些模型和假说并没有包括足够的裸子植物样本,特别是在亚热带栽培的针叶树种。我们在此研究了叶脉密度和叶功能性状的值和比例关系,这些样本来自于以快速生长著称的杉木(Cunninghamia lanceolata)的主要分布区。我们还检索了一个经验数据集,该数据集包括杉木的光合作用、生物化学、解剖学和水力特性。杉木叶脉密度(范围为0.34–1.09 mm/mm)远低于全球报道的范围(1–25 mm/mm),而杉木以快速生长和高产在中国长期闻名。我们进一步证实,较高的脉络密度与较小的叶片负相关(r=-0.71,P<0.001),这与被子植物中发现的情况一致。然而,我们发现,与全球物种(正相关)相比,杉木的叶脉密度-叶厚相关性和叶片寿命可塑性呈现相反的趋势,这种关系可能暗示功能效率和生产力间的权衡。我们的结果将为普适的生长规律提供有效的补充评估,包括评价区域植物性状特征、植物物种的配置和性状效率对水力潜能的影响。 | Xi Peng Meifang Zhao Shuguang Liu Wende Yan | 2023 | Journal of Plant Ecology2023，16，2： | 0 |
| 14 | Reply to comments on “Adsorption of 2-mercaptobenzothiazole from aqueous solution by organo-bentonite” by Yuhshan Ho显示文摘There were several first-order kinetic equations used and cited by previous publications(Do?an et al.,2007;Eftekhari et al.,2010;Lagergren,1898;Kannan and Sundaram,2001;zcan et al.,2006): | Ping Jing Meifang Hou Ping Zhao Xiaoyan Tang Hongfu Wan | 2014 | Journal of Environmental Sciences2014，26，12： | 0 |
| 15 | Temporally Separated CO_(2) Photoreduction and H_(2)O Photooxidation over Redox-Active Conjugated Organic Polymer Films显示文摘Photocatalytic CO_(2) reduction with H_(2)O of chemicals without H2 generation is interesting but challenging.Herein,we report temporally separated CO_(2) photoreduction and H_(2)O photooxidation that are achieved over redox-active o-hydroxyazo-based conjugated organic polymer films(HAzo-COPFs),affording CO with high efficiency as the sole reduction product.HAzo-COPFs are prepared via interfacial diazo-coupling reactions of aromatic diamines and diphenols,and HAzo-COPF-1 from 4,4′-biphenol and benzidine shows the best performance with a CO generation rate of 53.6μmol g−1 h−1 under visible-light irradiation(>420 nm).Interestingly,we discovered that diphenol(DP-OH)moieties in HAzo-COPFs,serving as electron and proton donors to participate in CO_(2) photoreduction,are oxidized into quinone(DP=O)moieties,which are subsequently photoreduced to regenerate DP-OH in H_(2)O photooxidation.Consequently,CO_(2) photoreduction and H_(2)O photooxidation are temporally separated and perfectly coupled via redox transformation between DP-OH and DP=O that form in situ,affording enhanced charge carrier separation and inhibiting the hydrogen evolution reaction.This work provides new insights for the design of COP photocatalysts and artificial photosynthesis. | Guipeng Ji Yuepeng Wang Wenqiang Ye Meifang Chen Fengtao Zhang Yanfei Zhao Shengrui Tong Buxing Han Zhimin Liu | 2023 | CCS Chemistry2023，5，8： | 0 |
| 16 | Association of human cytomegalovirus viremia with human leukocyte antigens in liver transplantation recipients显示文摘人的 cytomegalovirus (HCMV ) 复活是在肝移植(副) 以后的普通复杂并发症。这里,我们调查了匹配的人的白血球抗原(HLA ) 是否在为肝炎 B 病毒肝硬化的副以后与 HCMV 感染和随后的接枝失败有关。这回顾的研究考察了 91 个副接受者。所有病人根据 HLA 被组织 -- A, HLA-B,并且 HLA 医生地点匹配。临床的数据是镇定的,包括 HCMV viremia 的完全的打 HLA, HCMV viremia,接枝失败,和时间。打字的 HLA 用一个顺序特定的教材聚合酶链反应工具包被执行。HCMV 被 pp65 antigenemia 用一个商业工具包检测。HCMV 感染的发生副以后是 81.32% 。接枝失败在 91 中的 16 个被观察(17.6%) 病人在 4 年的学习期间。HCMV viremia 的发生是 100%(5/5 ) , 91.4%(32/35 ) ,并且 72.5%(37/51 ) 在 HLA -- 二个地点,一个地点,和零地点相容性分别地。不过, HLA 的度 -- A, HLA-B,或 HLA 医生火柴没在 HCMV viremia 的诊断以后影响接枝失败的 HCMV viremia,接枝失败,或时间的时间(所有 P > 0.05 ) 。有趣的发现是 HCMV viremia 的风险趋于在有更好的 HLA 的病人更高 -- 相容性。接枝失败, HCMV viremia 的时间,和在 HCMV viremia 的诊断以后的接枝失败看起来独立于 HLA 等位基因相容性。 | Jianhua Hu Xueqin Meng Hong Zhao Xuan Zhang Hainv Gao Meifang Yang Yadan Ma Minhuan Li Weihang Ma Jun Fan | 2011 | Acta Biochimica et Biophysica Sinica2011，43，7： | 0 |
| 17 | Diagnosis and Treatment Report of the First Case of Mycoplasma bovis in Shandong Province显示文摘[Objective] The paper was to introduce the first case of Mycoplasma bovis in Shandong Province.[Method] Samples were collected from sick cattle,and identified through M.bovis isolation,biochemical identification,PCR,16S RNA sequence analysis and clinical treatment and other research work.[Result] A strain of M.bovis was successfully isolated,and typical colonies in fried egg shape were grown.It was further confirmed as M.bovis via molecular biological detection.The use of vaccine and sensitive drugs in clinical could quickly control the epidemic situation of cat-tle herds.[Conclusion] This is the first reported case of M.bovis in Shandong Province,and its diagnosis and treatment process is conducive to further prevention and control of the disease. | Li Shuguang Liu Jishan Zhang Wei Wang Yumao Cheng Likun Yin Meifang Zhang Na Zhao Jialei Shen Zhiqiang | 2018 | Animal Husbandry and Feed Science2018，10，2： | 0 |
| 18 | The Physalis floridana genome provides insights into the biochemical and morphological evolution of Physalis fruits显示文摘The fruits of Physalis(Solanaceae)have a unique structure,a lantern-like fruiting calyx known as inflated calyx syndrome(ICS)or the Chinese lantern,and are rich in steroid-related compounds.However,the genetic variations underlying the origin of these characteristic traits and diversity in Physalis remain largely unknown.Here,we present a high-quality chromosome-level reference genome assembly of Physalis floridana(~1.40Gb in size)with a contig N50 of~4.87Mb.Through evolutionary genomics and experimental approaches,we found that the loss of the SEP-like MADS-box gene MBP21 subclade is likely a key mutation that,together with the previously revealed mutation affecting floral MPF2 expression,might have contributed to the origination of ICS in Physaleae,suggesting that the origination of a morphological novelty may have resulted from an evolutionary scenario in which one mutation compensated for another deleterious mutation.Moreover,the significant expansion of squalene epoxidase genes is potentially associated with the natural variation of steroid-related compounds in Physalis fruits.The results reveal the importance of gene gains(duplication)and/or subsequent losses as genetic bases of the evolution of distinct fruit traits,and the data serve as a valuable resource for the evolutionary genetics and breeding of solanaceous crops. | Jiangjie Lu Meifang Luo Li Wang Kunpeng Li Yongyi Yu Weifei Yang Pichang Gong Huihui Gao Qiaoru Li Jing Zhao Lanfeng Wu Mingshu Zhang Xueyang Liu Xuemei Zhang Xian Zhang Jieyu Kang Tongyuan Yu Zhimin Li Yuannian Jiao Huizhong Wang Chaoying He | 2021 | Horticulture Research2021，8，1： | 0 |
| 19 | Typical hemophagocytic syndrome associated with cytomegalovirus infection in an immunocompetent patient: a case report and literature review显示文摘Cytomegalovirus(CMV)infection is currently prevalent in populations throughout the world,and 56%-94%of the global population is seropositive for CMV.CMV infection mainly affects immunocompromised hosts.In these cases,it can cause significant symptoms,tissue-invasive disease,and many sequelae including death(Dioverti and Razonable,2016).The vast majority of healthy adults with CMV infection experience an asymptomatic course;when symptomatic,it manifests as a mononucleosis-like syndrome in approximately 10%of patients(Sridhar et al.,2018). | Fangfang GENG Meifang YANG Xuan ZHANG Hong ZHAO De ZHOU Jianhua HU | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，12： | 0 |
| 20 | Study on the Effect of Aqueous Extract of Houttuynia cordata on Serum TNF-αand IL-6 Content in Mice Infected with Five Common Pathogenic Bacteria显示文摘[Objectives]To observe the effect of aqueous extract of Houttuynia cordata on the content of serum TNF-αand IL-6 in mice with abdominal infection caused by Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa,Proteus vulgaris and Klebsiella pneumoniae,so as to investigate the antibacterial effect of aqueous extract of Houttuynia cordata in vivo.[Methods]A total of 72 KM mice were randomly divided into six groups:model group,blank group,cefdinir dispersible tablet group(0.25 g/kg),high,medium and low dose groups of aqueous extract of Houttuynia cordata(40,20,10 g/kg crude drug).There were 12 mice in each group,half male and half female,continuously given intragastric administration for three days,once a day.The blank group and the model group were intragastrically infused with normal saline,and the other groups were given corresponding drugs with a volume of 0.02 mL/g.After 30 min of administration on the third day,the mice were injected intraperitoneally with 0.5 mL of bacterial suspension to make bacterial infection.The mice in the blank group were intraperitoneally injected with the same amount of normal saline,followed by intragastric administration 6 h after intraperitoneal injection and intragastric administration again after 24 h.The mice were observed for three days,and the changes of body weight before and after infection were recorded.On the fourth day of infection,eyeball blood was taken,serum was separated,and the concentration of inflammatory factors TNF-αand IL-6 in serum was determined.[Results]Compared with the model group,the high,medium and low dose groups of H.cordata aqueous extract had protective effects on mice with abdominal infection caused by S.aureus,E.coli,P.aeruginosa,P.vulgaris and K.pneumoniae,and decreased the content of TNF-αand IL-6 in serum.[Conclusions]The aqueous extract of H.cordata had a certain antibacterial effect on acute abdominal infection caused by S.aureus,E.coli,P.aeruginosa,P.vulgaris and K.pneumoniae,and its mechanism was related to TNF-αand IL-6. | Meiyuan LU Chunli TANG Fengxian ZHAO Xiaoyu HUANG Hongxia CHEN Meifang LI | 2020 | Medicinal Plant2020，11，5： | 0 |
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