维普中文期刊产品整合服务
31篇 您的检索式:作者名="Ze Cao"
    题名 作者 年代 出处 被引量
1High salt diet accelerates the progression of murine lupus through dendritic cells via the p38 MAPK and STAT1 signaling pathways显示文摘The increased incidence of systemic lupus erythematosus(SLE)in recent decades might be related to changes in modern dietary habits.Since sodium chloride(NaCl)promotes pathogenic T cell responses,we hypothesize that excessive salt intake contributes to the increased incidence of autoimmune diseases,including SLE.Given the importance of dendritic cells(DCs)in the pathogenesis of SLE,we explored the influence of an excessive sodium chloride diet on DCs in a murine SLE model.We used an induced lupus model in which bone marrow-derived dendritic cells(BMDCs)were incubated with activated lymphocyte-derived DNA(ALD-DNA)and transferred into C57BL/6 recipient mice.We observed that a high-salt diet(HSD)markedly exacerbated lupus progression,which was accompanied by increased DC activation.NaCl treatment also stimulated the maturation,activation and antigenpresenting ability of DCs in vitro.Pretreatment of BMDCs with NaCl also exacerbated BMDC-ALD-DNA-induced lupus.These mice had increased production of autoantibodies and proinflammatory cytokines,more pronounced splenomegaly and lymphadenopathy,and enhanced pathological renal lesions.The p38 MAPK–STAT1 pathway played an important role in NaClinduced DC immune activities.Taken together,our results demonstrate that HSD intake promotes immune activation of DCs through the p38 MAPK–STAT1 signaling pathway and exacerbates the features of SLE.Thus,changes in diet may provide a novel strategy for the prevention or amelioration of lupus or other autoimmune diseases.Ze Xiu Xiao Xiaojiang Hu Ximei Zhang Zhigang Chen Julie Wang Ke Jin Feng Lin Cao Baoqing Sun Joseph A.Bellanti Nancy Olsen Song Guo Zheng 2020Signal Transduction and Targeted Therapy2020,5,1:6
2Association between single nucleotide polymorphisms on chromosome 17q and the risk of prostate cancer in a Chinese population显示文摘In European populations,7 single nucleotide polymorphisms(SNPs) on chromosome 17q,3 SNPs on 17q12,and 4 SNPs on 17q24.3 were recently identified to be closely related to the risk of prostate cancer by a genome-wide association study.In Japanese populations,the correlation between 2 SNPs on 17q and the risk of prostate cancer and tumor aggressiveness was also confirmed by a large-scale experiment.However,whether 17q is associated with prostate cancer and its clinical manifestations in Chinese populations is still unknown.Therefore,we conducted a case-control study in a northern Chinese population and tested 2 SNPs,rs4430796 and rs1859962,on 17q in 124 prostate cancer patients and 111 controls using polymerase chain reaction-high resolution melting curve(PCR-HRM) combined with sequencing.We analyzed the association of the 2 SNPs with the risk of prostate cancer as well as patients' lifestyles,onset ages,Gleason scores,PSA levels,and pathologic stages.We found a significant difference in the G allele of SNP rs1859962(P = 0.035,OR = 1.51,95% CI = 1.03-2.21) but not in the rs4430796 genotype frequency or allele frequency distribution between prostate cancer patients and the controls(P > 0.05).Neither of the SNPs was significantly associated with the onset age,Gleason score,PSA level,pathologic stage,or other clinical indicators of patients with prostate cancer(P > 0.05).Our results show that polymorphism of the G allele of SNP rs1859962 is associated with the risk of prostate cancer in a Chinese population.Chang-Hu Zhou Jian-Ye Wang Su-Yan Cao Xiao-Hong Shi Yao-Guang Zhang Ming Liu Xin wang Jin Huang Yi-Ge Yang Dong Wei Ze Yang 2011Chinese Journal of Cancer2011,30,10:4
3Back-n white neutron source at CSNS and its applications显示文摘Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n white neutron source),which was completed in March 2018.The Back-n neutron beam is very intense,at approximately 29107 n/cm2/s at 55 m from the target,and has a nominal proton beam with a power of 100 kW in the CSNS-I phase and a kinetic energy of 1.6 GeV and a thick tungsten target in multiple slices with modest moderation from the cooling water through the slices.In addition,the excellent energy spectrum spanning from 0.5 eV to 200 MeV,and a good time resolution related tothe time-of-flight measurements make it a typical white neutron source for nuclear data measurements;its overall performance is among that of the best white neutron sources in the world.Equipped with advanced spectrometers,detectors,and application utilities,the Back-n facility can serve wide applications,with a focus on neutron-induced cross-sectional measurements.This article presents an overview of the neutron beam characteristics,the experimental setups,and the ongoing applications at Backn.Jing-Yu Tang Qi An Jiang-Bo Bai Jie Bao Yu Bao Ping Cao Hao-Lei Chen Qi-Ping Chen Yong-Hao Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Xing-Yan Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Yi-Wei Yang Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 2021Nuclear Science and Techniques2021,32,1:4
4Elastic Scattering of 7Be on Pb Target显示文摘Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing 2011IMP & HIRFL Annual Report2011,,1:4
5Exosomal PD-L1 induces osteogenic differentiation and promotes fracture healing by acting as an immunosuppressant显示文摘A moderate inflammatory response at the early stages of fracture healing is necessary for callus formation.Over-active and continuous inflammation,however,impairs fracture healing and leads to excessive tissue damage.Adequate fracture healing could be promoted through suppression of local over-active immune cells in the fracture site.In the present study,we achieved an enriched concentration of PD-L1 from exosomes(Exos)of a genetically engineered Human Umbilical Vein Endothelial Cell(HUVECs),and demonstrated that exosomes overexpressing PD-L1 specifically bind to PD-1 on the T cell surface,suppressing the activation of T cells.Furthermore,exosomal PD-L1 induced Mesenchymal Stem Cells(MSCs)towards osteogenic differentiation when pre-cultured with T cells.Moreover,embedding of Exos into an injectable hydrogel allowed Exos delivery to the surrounding microenvironment in a time-released manner.Additionally,exosomal PD-L1,embedded in a hydrogel,markedly promoted callus formation and fracture healing in a murine model at the early over-active inflammation phase.Importantly,our results suggested that activation of T cells in the peripheral lymphatic tissues was inhibited after local administration of PD-L1-enriched Exos to the fracture sites,while T cells in distant immune organs such as the spleen were not affected.In summary,this study provides the first example of using PD-L1-enriched Exos for bone fracture repair,and highlights the potential of Hydrogel@Exos systems for bone fracture therapy through immune inhibitory effects.Ze Lin Yuan Xiong Weilin Meng Yiqiang Hu Lili Chen Lang Chen Hang Xue Adriana CPanayi Wu Zhou Yun Sun Faqi Cao Guodong Liu Liangcong Hu Chenchen Yan Xudong Xie Chuanchuan Lin Kaiyong Cai Qian Feng Bobin Mi Guohui Liu 2022Bioactive Materials2022,7,7:4
6Transparent perovskite glass-ceramics for visual optical thermometry显示文摘Optical thermometers have aroused considerable attention in recent years,and the increasing demand of sensitivity for practical application encourages the investigation on developing innovative non-contact optical thermo metric materials with higher sensitivity and accuracy.Perovskite quantum dots(QDs)with excellent temperature-dependence optical properties,provide a feasible approach to realizing the detection of temperature change,however,their poor high temperature thermal stability and the facile realization to obtain the production remain a daunting challenge.Herein,growing Tb^(3+)-doped CsPbl_(3) QDs in situ in borosilicate glass is proposed,which ensures the phase stability,and high-efficiency florescence output of the all-inorganic perovskite as a temperature sensor.A higher absolute and relative temperature sensitivity(0.0398 K^(-1) and 7.12%/K,respectively),along with the visible color change from orange-red to yellow-green with the increase of temperature is accomplished.Notably,the repeatable florescence intensity of Tb^(3+)-doped CsPbl_(3) QDs under high temperature enables their temperature sensing application.Qihua Yang Lei Zhao Zhaohui Fang Ze Yang Jiangyan Cao Yiyu Cai Dacheng Zhou Xue Yu Jianbei Qiu Xuhui Xu 2021Journal of Rare Earths2021,39,6:3
7Valence Bond Study of Dissociation Behavior and Spectroscopic Constants for the Ground States of LiF and NaF显示文摘IntroductionThealkalihalidediatomicmoleculesprovideatypicalcurvecrosingproblem[1].Theoutstandingnonadiabaticbehaviorofthechem...CAO Ze xing ** , WU Wei and ZHANG Qian er (Department of Chemistry, State Key Laboratory for Physical Chemistry of the Surface Science, and Institute of Physical Chemistry, Xiamen University, Xiamen, 361005) 1998Chemical Research in Chinese Universities1998,14,3:3
8Multi-Source Data Privacy Protection Method Based on Homomorphic Encryption and Blockchain显示文摘Multi-Source data plays an important role in the evolution of media convergence.Its fusion processing enables the further mining of data and utilization of data value and broadens the path for the sharing and dissemination of media data.However,it also faces serious problems in terms of protecting user and data privacy.Many privacy protectionmethods have been proposed to solve the problemof privacy leakage during the process of data sharing,but they suffer fromtwo flaws:1)the lack of algorithmic frameworks for specific scenarios such as dynamic datasets in the media domain;2)the inability to solve the problem of the high computational complexity of ciphertext in multi-source data privacy protection,resulting in long encryption and decryption times.In this paper,we propose a multi-source data privacy protection method based on homomorphic encryption and blockchain technology,which solves the privacy protection problem ofmulti-source heterogeneous data in the dissemination ofmedia and reduces ciphertext processing time.We deployed the proposedmethod on theHyperledger platformfor testing and compared it with the privacy protection schemes based on k-anonymity and differential privacy.The experimental results showthat the key generation,encryption,and decryption times of the proposedmethod are lower than those in data privacy protection methods based on k-anonymity technology and differential privacy technology.This significantly reduces the processing time ofmulti-source data,which gives it potential for use in many applications.Ze Xu Sanxing Cao 2023Computer Modeling in Engineering & Sciences2023,,7:2
9Electronic spectra of the linear polyyne cations HC2n H^+ (n = 2-8): An ab initio study 显示文摘ZHANG Jing Lai GUO Xu Geng CAO Ze Xing 2009J Chem Phys2009,131,14:1
10Atomistic dynamics of disconnection-mediated grain boundary plasticity:A case study of gold nanocrystals显示文摘Grain boundary(GB)mediated deformation is a vital contributor to the plasticity of polycrystalline materials,where the disconnection model has become a widely recognized approach to depict the GB dynamics.However,experimental understanding of the atomistic disconnection dynamics remains scarce.In this case study of gold nanocrystals,atomistic disconnection dynamics governing the shear-coupled migration of flat GBs have been systematically investigated via in situ transmission electron microscopy nanomechanical testing supported by molecular dynamics simulations.Specifically,the site-dependent nucleation,shear-driven propagation,and diverse interactions associated with distinct GB disconnections are systematically elucidated and quantitatively compared.Moreover,the disconnection-mediated GB plasticity proves to prevail among different tilt and mixed GBs in gold.Eventually,a conceptual map of disconnection-mediated GB dynamics is established,which would furnish a unified understanding of GB plasticity in metallic materials.Qi Zhu Haofei Zhou Yingbin Chen Guang Cao Chuang Deng Ze Zhang Jiangwei Wang 2022Journal of Materials Science & Technology2022,,30:1
11Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence显示文摘Deregulated telomere length is a causative factor in many physiological and pathological processes,including aging and cancer.Many studies focusing on telomeres have revealed important roles for cooperation between the Shelterin protein complex and telomerase in maintaining telomere length.However,it remains largely unknown whether and how aging-related stresses,such as deregulated protein homeostasis,impact telomere length.Here,we explored the possible roles of aminoacyl tRNA synthetases(AARSs),key enzymes catalyzing the first reactions in protein synthesis,in regulating telomere length and aging.We selected seryl tRNA synthetase(SerRS)since our previous studies discovered expanded functions of SerRS in the nucleus in addition to its canonical cytoplasmic role in protein synthesis.In this study,we revealed that overexpression of SerRS promoted cellular senescence and inhibited the growth of cervical tumor xenografts in mice by triggering the senescence of tumor cells.In the nucleus,SerRS directly bound to telomeric DNA repeats and tethered more POT1 proteins to telomeres through a direct interaction between the UNE-S domain of SerRS and the OB1 domain of POT1.We further demonstrated that SerRS-induced enrichment of POT1 prevented the recruitment of telomerase to telomeres,resulting in progressive telomere shortening.Our data suggested a possible molecular link between protein synthesis and telomere length control,the deregulation of which may be associated with aging and cancer.Yingxi Li Xiyang Li Mei Cao Yuke Jiang Jie Yan Ze Liu Rongcun Yang Xu Chen Peiqing Sun Rong Xiang Longlong Wang Yi Shi 2019Signal Transduction and Targeted Therapy2019,4,1:1
12A novel strategy for producing high-performance continuous regenerated fibers with wool-like structure显示文摘We proposed a novel approach to prepare high-performance continuous regenerated keratin fibers with wool-like structure by using the cortical cells and linear keratin from wool waste as reinforcement and adhesive,respectively.The spindle-shaped cortical cells were taken from wool waste based on the different responses of cortical cells and mesenchyme in wool to the treatments of H_(2)O_(2) oxidation and ultrasonication.The linear keratin was yielded through dissolving wool waste in the green solution consisting of starch derived dithiothreitol and protein denaturant sodium dodecyl sulfate.The recycled keratin fibers were produced by wet-spinning of the mixture solution comprising of cortical cells,linear keratin and toughener poly(ethylene glycol)diacrylate,and crosslinked by glutaraldehyde and 4,4′-methylenebis-(phenyl isocyanate).The cortical cells were aligned along the regenerated fibers axis and retained quite a fewα-helical crystals of the intermediate filaments,benefitting improvement of mechanical properties.Consequently,the valuable chemical compositions and hierarchical microstructures of wool were largely inherited.Their mechanical properties,thermal stability,dyeing property,moisture absorption capability,and antistatic resistance resembled those of wool.The regenerated fibers contained 93.3 wt.%components of wool,and the amount of synthetic chemicals in the regenerated fibers was controlled to as low as 6.7 wt.%.Guang Sheng Cao Ze Ping Zhang Min Zhi Rong Ming Qiu Zhang 2022SusMat2022,2,1:1
13Monitoring the morphology evolution of LiNi_(0.8)Mn_(0.1)Co_(0.1)O_(2)during high-temperature solid state synthesis via in situ SEM显示文摘The particle morphology determined by the sintering process is the director factor affecting the electrochemical performance of Ni-rich NMC cathode materials.To prepare the ideal NMC particles,it is of great significance to understand the morphological changes during sintering process.In this work,the morphology evolution of LiNi_(0.8)Mn_(0.1)Co_(0.1)O_(2)(NMC811)synthesis at temperature ranging from 300–1080℃were observed by in situ SEM.The uniform mixture of spherical Ni_(0.8)Mn_(0.1)Co_(0.1)(OH)_(2)precursor and lithium sources(LiOH)was employed by high temperature solid-state process inside the SEM,which enables us to observe morphology changes in real time.The results show that synthetic reaction of LiNi_(0.8)Mn_(0.1)Co_(0.1)O_(2)usually includes three processes:the raw materials’dehydration,oxidation,and combination,accompanied by a significant reduction in particle size,which is important reference to control the synthesis temperature.As heating temperature rise,the morphology of mixture also changed from flake to brick-shaped.However,Ni nanoparticle formation is apparent at higher temperature~1000℃,suggesting a structural transformation from a layered to a rock-salt-like structure.Combining the in-situ observed changes in size and morphology,and with the premise of ensuring the morphology change from flakes to bricks,reducing the sintering temperature as much as possible to prevent excessive reduction in particle size and layered to a rock-salt structure transformation is recommended for prepare ideal NMC particles.Liang Tang Xiaopeng Cheng Rui Wu Tianci Cao Junxia Lu Yuefei Zhang Ze Zhang 2022Journal of Energy Chemistry2022,31,3:1
14Measurement of the ^(232)Th(n,f)cross section in the 1-200 MeV range at the CSNS Back-n显示文摘The ^(232)Th(n,f)cross section is very important in basic nuclear physics and applications based on the Th/U fuel cycle.Using the time-of-flight method and a multi-cell fast-fission ionization chamber,a novel measurement of the^(232)Th(n,f)cross sec-tion relative to^(235)U in the 1–200 MeV range was performed at the China Spallation Neutron Source Back-n white neutron source(Back-n).The fission event-neutron energy spectra of^(232)Th and^(235)U fission cells were measured in the single-bunch mode.Corrected 232Th/235U fission cross-sectional ratios were obtained,and the measurement uncertainties were 2.5–3.7%for energies in the 2–20 MeV range and 3.6–6.2%for energies in the 20–200 MeV range.The^(232)Th(n,f)cross section was obtained by introducing the standard cross section of^(235)U(n,f).The results were compared with those of previous theoreti-cal calculations,measurements,and evaluations.The measured 232Th fission cross section agreed with the main evaluation results in terms of the experimental uncertainty,and 232Th fission resonances were observed in the 1–3 MeV range.The present results provide^(232)Th(n,f)cross-sectional data for the evaluation and design of Th/U cycle nuclear systems.Zhi-Zhou Ren Yi-Wei Yang Yong-Hao Chen Rong Liu Bang-Jiao Ye Jie Wen Hai-Rui Guo Zi-Jie Han Qi-Ping Chen Zhong-Wei Wen Wei-Li Sun Han Yi Xing-Yan Liu Tao Ye Jiang-Bo Bai Qi An Jie Bao Yu Bao Ping Cao Hao-Lei Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Shu-Bin Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Jing-Yu Tang Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 2023Nuclear Science and Techniques2023,34,8:1
15Upregulation of chicken TLR4, TLR15 and MyD88 in heterophils and monocyte-derived macrophages stimulated with Eimeria tenella in vitro显示文摘Zuoyong Zhou Zhiying Wang Liting Cao Shijun Hu Ze Zhang Bo Qin Zhili Guo Kui Nie 2013Experimental Parasitology2013,,4:1
16Polarization insensitive all-optical up-conversion for ROF systems based on parallel pump FWM in a SOA 显示文摘Lu Jia Dong Ze Cao Zizeng 2009OPTICS EXPRESS2009,,27:1
17Downregulation of hepatoma-derived growth factor suppresses the malignantphenotype of U87 human glioma cells显示文摘Aixia Zhang Weiguo Long Ze Guo Zhenying Guo Brian Cao 2012Oncology Reports2012,,1:1
18Tandem 180 stable iso- tope labeling for quantification of N-glycoproteome显示文摘LIU Ze CAO Jing HE Yifeng 2009Journal of proteome research2009,9,1:1
19LIWRKY39 is involved in thermotolerance by activating LIMBF1c and interacting with LICaM3 in lily(Lilium longiflorum)显示文摘WRKY transcription factors(TFs)are of great importance in plant responses to different abiotic stresses.However,research on their roles in the regulation of thermotolerance remains limited.Here,we investigated the function of LlWRKY39 in the thermotolerance of lily(Lilium longiflorum‘white heaven’).According to multiple alignment analyses,LIWRKY39 is in the WRKY IId subclass and contains a potential calmodulin(CaM)-binding domain.Further analysis has shown that LlCaM3 interacts with LlWRKY39 by binding to its CaM-binding domain,and this interaction depends on Ca^(2).LIWRKY39 was induced by heat stress(HS),and the LIWRKY39-GFP fusion protein was detected in the nucleus.The thermotolerance of lily and Arabidopsis was increased with the ectopic overexpression of LlWRKY39.The expression of heat-related genes AtHSFA1,AtHSFA2,AtMBF1c,AtGolS1,AtDREB2A,AtWRKY39,and AtHSP101 was significantly elevated in transgenic Arabidopsis lines,which might have promoted an increase in thermotolerance.Then,the promoter of LlMBF1c was isolated from lily,and LlWRKY39 was found to bind to the conserved W-box element in its promoter to activate its activity,suggesting that LlWRKY39 is an upstream regulator of LlMBF1c.In addition,a dual-luciferase reporter assay showed that via protein interaction,LlCaM3 negatively affected LlWRKY39 in the transcriptional activation of LlMBF1c,which might be an important feedback regulation pathway to balance the LlWRKY39-mediated heat stress response(HSR).Collectively,these results imply that LlWRKY39 might participate in the HSR as an important regulator through Ca^(2+)-CaM and multiprotein bridging factor pathways.Liping Ding Ze Wu Renda Teng Sujuan Xu Xing Cao Guozhen Yuan Dehua Zhang Nianjun Teng 2021Horticulture Research2021,8,1:1
20Brainstem auditory electrophysiology is supressed in term neonates with hyperbilirubinemia显示文摘Ze D. Jiang T.T. Liu Cao Chen 2013European Journal of Paediatric Neurology2013,,:1
返回顶部 每页显示:
共2页 首页 上一页 第1页 下一页 末页 /2 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费