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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Adakite-type sodium-rich rocks in Awulale Mountain of west Tianshan:Significance for the vertical growth of continental crust显示文摘The sodium-rich dacites and albite porphyries of Permian in the Awulale Mountain of west Tianshan have unique chemical and trace element signatures identical to adakite. These intermediate-acidic igneous rocks are characterized by high Na2O, Al2O3 and Sr contents and high Sr/Y and La/Y ratios (>40 and >20, respectively), and low Y and Yb contents, and strong depletion in HREE, and positive Eu anomaly. The (143Nd/144Nd)i is in the range from0.51236 to 0.51248 and the εNd(t) is positive value (+0.79-+3.11); the (87Sr/86Sr)i is in the range from 0.7052 to 0.7054. These Nd and Sr isotopic composition features indicate that the source rocks of these adakite-type rocks are from a weakly depleted mantle, or a depleted mantle, but was contaminated by the crustal materials. These adakite-type rocks were most likely derived from the partial melting of new underplated basaltic rocks under the conditions of amphibo-lite to eclogite transition in the postcollisional environment of North Xinjiang during the Permian | XIONG Xiaolin ZHAO Zhenhua BAI Zhenghua MEI Houjun WANG Yixian WANG Qiang XU Jifeng Niu Hecai BAO Zhiwei | 2001 | Chinese Science Bulletin2001，46，10： | 25 |
| 3 | Selective laser melting of NiTi alloy with superior tensile property and shape memory effect显示文摘It is a challenge to develop complex-shaped Ni Ti shape memory alloy parts by traditional processing methods, due to the poor machinability of Ni Ti alloy. It is reported that selective laser melting(SLM) of additive manufacturing could overcome this problem. However, the reported SLM-produced Ni Ti exhibits poor tensile ductility due to the inner defects and adverse unidirectional columnar grains from SLM process. In this work, the defect-less SLM-Ni Ti with nondirective columnar grains was fabricated by optimizing the intraformational laser scanning length and interformational laser scanning direction. The obtained lath-shaped SLM-Ni Ti sample exhibits tensile strain of 15.6%, more than twice of the reported maximum result(7%). Besides, the SLM-Ni Ti part with complex geometry displays a shape memory recovery of 99% under compressive deformation of 50%. | Zhiwei Xiong Zhonghan Li Zhen Sun Shijie Hao Ying Yang Meng Li Changhui Song Ping Qiu Lishan Cui | 2019 | Journal of Materials Science & Technology2019，35，10： | 15 |
| 4 | Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution显示文摘The speed of high-resolution optical imaging has been a rate-limiting factor for meso-scale mapping of brain structures and functional circuits,which is of fundamental importance for neuroscience research.Here,we describe a new microscopy method of Volumetric Imaging with Synchronized on-the-fly-scan and Readout(VISo R)for high-throughput,high-quality brain mapping.Combining synchronized scanning beam illumination and oblique imaging over cleared tissue sections in smooth motion,the VISo R system effectively eliminates motion blur to obtain undistorted images.By continuously imaging moving samples without stopping,the system achieves high-speed 3D image acquisition of an entire mouse brain within1.5 hours,at a resolution capable of visualizing synaptic spines.A pipeline is developed for sample preparation,imaging,3D image reconstruction and quantification.Our approach is compatible with immunofluorescence methods,enabling flexible cell-type specific brain mapping and is readily scalable for large biological samples such as primate brains.Using this system,we examined behaviorally relevant whole-brain neuronal activation in 16 c-Fos-sh EGFP mice under resting or forced swimming conditions.Our results indicate the involvement of multiple subcortical areas in stress response.Intriguingly,neuronal activation in these areas exhibits striking individual variability among different animals,suggesting the necessity of sufficient cohort size for such studies. | Hao Wang Qingyuan Zhu Lufeng Ding Yan Shen Chao-Yu Yang Fang Xu Chang Shu Yujie Guo Zhiwei Xiong Qinghong Shan Fan Jia Peng Su Qian-Ru Yang Bing Li Yuxiao Cheng Xiaobin He Xi Chen Feng Wu Jiang-Ning Zhou Fuqiang Xu Hua Han Pak-Ming Lau Guo-Qiang Bi | 2019 | National Science Review2019，6，5： | 7 |
| 5 | Questions about NgAgo显示文摘 | Shawn Burgess Linzhao Cheng Feng Gu Zhiwei Huang Shuo Lin Jinsong Li Wei Li Wei Qin Yujie Sun Zhou Songyang Wensheng Wei Qiang Wu Haoyi Wang Xiaoqun Wang Jing-Wei Xiong Jianzhong Xi Hui Yang Bin Zhou Bo Zhang Junjiu Huang | 2016 | Protein & Cell2016，7，12： | 5 |
| 6 | LPI radar signal detection based on the combination of FFT and segmented autocorrelation plus PAHT显示文摘This paper proposes a desirable method to detect different kinds of low probability of intercept(LPI) radar signals, targeted at the main intra-pulse modulation method of LPI radar signals including the signals of linear frequency modulation, phase code,and frequency code. Firstly, it improves the coherent integration of LPI radar signals by adding the periodicity of the ambiguity function. Then, it develops a frequency domain detection method based on fast Fourier transform(FFT) and segmented autocorrelation function to detect signals without features of linear frequency modulation by virtue of the distribution characteristics of noise signals in the frequency domain. Finally, this paper gives a verification of the performance of the method for different signal-to-noise ratios by conducting simulation experiments, and compares the method with existing ones. Additionally, this method is characterized by the straightforward calculation and high real-time performance, which is conducive to better detecting all kinds of LPI radar signals. | Chengzhi Yang Zhiwei Xiong Yang Guo Bolin Zhang | 2017 | Journal of Systems Engineering and Electronics2017，28，5： | 3 |
| 7 | Subtyping of type A influenza by sequencing the variable regions of HA gene specifically amplified with RT-PCR显示文摘The outbreak of a novel influenza A(H1N1) virus across the globe poses a threat to human health.It is of paramount importance to develop a rapid,reliable and inexpensive diagnostic procedure.Based on the bioinformatic information from public database,primers specific for influenza A virus surface protein haemagglutinin(HA) of several subtypes(including H1,H2,H3,H5,H7 and H9) were designed.Primer-specific PCR products were subjected to sequencing for accurately distinguishing H1 and H3 subtypes from others.This sequencing-based detection method will not only be applied to rapid detection and simultaneous subtype identification of new influenza A virus H1N1,but also provide the strategies to monitor other new types ofinfluenza virus with explosive potential. | YAN An DING GuoHui ZHOU ZhenFeng DONG Hui ZHANG YaKun ZHU Lei HE YunGang ZHANG GuoQing LI YiXue SUN Bing HUANG Zhong LAN Ke JIN Li WANG HongYan WANG XiaoNing YANG Zhong ZHONG Yang DAI JianXin GUO YaJun WANG Hao CHE XiaoYan WU Fan YUAN ZhenGan ZHANG Xi CAO ZhiWei ZHOU XiaoNong ZHOU JiaHai MA ZhiYong TONG GuangZhi ZHAO GuoPing JIN WeiRong XIONG Hui | 2009 | Chinese Science Bulletin2009，54，13： | 3 |
| 8 | The mutation network for the hemagglutinin gene from the novel influenza A (H1N1) virus显示文摘A mutation network for the hemagglutinin gene(HA) of the novel type A(H1N1) influenza virus was constructed.Sequence homology analysis indicated that one HA sequence type from the viruses mainly isolated from Mexico was likely the original type in this epidemic.Based on the 658A and 1408T mutations in HA,the viruses evolving into this epidemic were divided into three categories,the Mexico,the transitional and the New York type.The three groups of viruses presented distinctive clustering features in their geographic distributions. | HE YunGang DING GuoHui BIAN Chao HUANG Zhong LAN Ke SUN Bing WANG XueCai LI YiXue WANG HongYan WANG XiaoNing YANG Zhong ZHONG Yang JIN WeiRong XIONG Hui DAI JianXin GUO YaJun WANG Hao CHE XiaoYan WU Fan YUAN ZhenAn ZHANG Xi CAO ZhiWei ZHOU XiaoNong ZHOU JiaHai MA ZhiYong TONG GuangZhi ZHAO GuoPing JIN Li | 2009 | Chinese Science Bulletin2009，54，13： | 3 |
| 9 | Multiple sgRNAs facilitate base editingmediated i-stop to induce complete and precise gene disruption显示文摘Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9)system has been demonstrated as a versatile tool for engineering eukaryote genome(Hsu et al.,2014),such as in mice(Zuo et al.,2017). | Kun Jia Zongyang Lu Fei Zhou Zhiqi Xiong Rui Zhang Zhiwei Liu Yu'e Ma Lei He Cong Li Zhen Zhu Dejing Pan Zhengxing Lian | 2019 | Protein & Cell2019，10，11： | 3 |
| 10 | Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure–activity relationship, crystal structural characterization and in vivo study显示文摘Genomic alterations are commonly found in the signaling pathways of fibroblast growth factor receptors(FGFRs). Although there is no selective FGFR inhibitors in market, several promising inhibitors have been investigated in clinical trials, and showed encouraging efficacies in patients. By designing a hybrid between the FGFR-selectivity-enhancing motif dimethoxybenzene group and our previously identified novel scaffold, we discovered a new series of potent FGFR inhibitors, with the best one showing sub-nanomolar enzymatic activity. After several round of optimization and with the solved crystal structure, detailed structure–activity relationship was elaborated. Together with in vitro metabolic stability tests and in vivo pharmacokinetic profiling, a representative compound(35) was selected and tested in xenograft mouse model, and the result demonstrated that inhibitor 35 was effective against tumors with FGFR genetic alterations, exhibiting potential for further development. | Peng Wei Bo Liu Ruifeng Wang Yinglei Gao Lanlan Li Yuchi Ma Zhiwei Qian Yuelei Chen Maosheng Cheng Meiyu Geng Jingkang Shen Dongmei Zhao Jing Ai Bing Xiong | 2019 | Acta Pharmaceutica Sinica B2019，9，2： | 2 |
| 11 | Structure modeling and spatial epitope analysis for HA protein of the novel H1N1 influenza virus显示文摘In recent months,a novel influenza virus H1N1 broke out around the world.With bioinformatics technology,the 3D structure of HA protein was obtained,and the epitope residues were predicted with the method developed in our group for this novel flu virus.58 amino acids were identified as potential epitope residues,the majority of which clustered at the surface of the globular head of HA protein.Although it is located at the similar position,the epitope of HA protein for the novel H1N1 flu virus has obvious differences in the electrostatic potential compared to that of HA proteins from previous flu viruses. | WU Di XU TianLei SUN Jing DAI JianXin DING GuoHui HE YunGang ZHOU ZhengFeng XIONG Hui DONG Hui JIN WeiRong BIAN Chao JIN Li WANG HongYan WANG XiaoNing YANG Zhong ZHONG Yang WANG Hao CHE XiaoYan HUANG Zhong LAN Ke SUN Bing WU Fan YUAN ZhenAn ZHANG Xi ZHOU XiaoNong ZHOU JiaHai MA ZhiYong TONG GuangZhi GUO YaJun ZHAO GuoPing LI YiXue CAO ZhiWei | 2009 | Chinese Science Bulletin2009，54，13： | 2 |
| 12 | Dying tumor cells stimulate proliferation of living tumor cells via caspase-dependent protein kinase Cδ activation in pancreatic ductal adenocarcinoma显示文摘 | Jin Cheng Ling Tian Jingjing Ma Yanping Gong Zhengxiang Zhang Zhiwei Chen Bing Xu Hui Xiong Chuanyuan Li Qian Huang | 2014 | Molecular Oncology2014，，： | 1 |
| 13 | MicroRNA-101 suppresses SOX9-dependent tumorigenicity and promotes favorable prognosis of human hepatocellular carcinoma显示文摘 | Yanqiong Zhang<.--Q1: Please confirm that given names and surnames have been identified correctly.--> Xiaodong Guo Lu Xiong Xiangying Kong Ying Xu Chunfang Liu Lin Zou Zhiwei Li Jingmin Zhao Na Lin | 2012 | FEBS Letters2012，，： | 1 |
| 14 | 靶向表观遗传相互作用为EZH2异常的实体瘤群体提供精准治疗策略显示文摘文章简介表观遗传调控异常与肿瘤发生发展密切相关,其中组蛋白甲基转移酶EZH2因在肿瘤中广泛突变和过表达,成为备受关注肿瘤治疗靶点,多个抑制剂处于临床研究。然而,目前EZH2抑制剂仅对少量血液系统肿瘤有效,对实体瘤治疗基本无效,极大限制了其临床应用空间。 | Xun Huang Juan Yan Min Zhang Yafang Wang Yi Chen Xuhong Fu Rongrui Wei Xing-ling Zheng Zhiwei Liu Xiong Zhang Hong Yang Bingbing Hao Yan-yan Shen Yi Su Xiaoji Cong Min Huang 谭敏佳 丁健 耿美玉 | 2019 | 科学新闻2019，0，2： | 1 |
| 15 | Highly active N,O-doped hierarchical porous carbons for high-energy supercapacitors显示文摘Highly active N,O-doped hierarchical porous carbons(NOCs)are fabricated through the in-situ polymerization and pyrolysis of o-tolidine and p-benzoquinone.As-prepared NOCs have a variety of faradaic-active species(N-6,N-5 and O-I),high ion-accessible platform(1799 m^2/g)and hierarchically micro-meso-macro porous architecture.Consequently,the resultant NOC electrode delivers an advantageous specific capacitance(311 F/g),with a pseudocapacitive contribution of 37%in a threeelectrode configuration,and an enhanced energy output of 18.0 Wh/kg@350 W/kg owing to the enlarged faradaic effect in an aqueous redox-active cell.Besides,a competitive energy density(74.9 Wh/kg)and high-potential durability(87.8%)are achieved in an ionic liquid(EMIMB F4)-assembled device.This study sheds light on a straightforward avenue to optimize the faradaic activity and nanoarchitecture for advanced supercapacitors. | Ziyang Zhou Hui Duan Zhiwei Wang Yaokang Lv Wei Xiong Dazhang Zhu Liangchun Li Mingxian Liu Lihua Gan | 2020 | Chinese Chemical Letters2020，31，5： | 1 |
| 16 | Ladar range image denoising by a non-local probability statistics algorithm 显示文摘 | Xia Zhiwei Li Qi Xiong Zhipeng | 2013 | Optical Engineering2013，52，01： | 1 |
| 17 | Model Predictive Direct Power Control of Grid-connected Converters Considering Unbalanced Filter Inductance and Grid Conditions显示文摘The grid-connected converter(GCC) is widely used as the interface between various distributed generations and the utility grid. To achieve precise power control for GCC, this paper presents a model predictive direct power control(MPDPC)with consideration of the unbalanced filter inductance and grid conditions. First, the characteristics of GCC with unbalanced filter inductance are analyzed and a modified voltage control function is derived. On this basis, to compensate for the power oscillation caused by unbalanced filter inductance, a novel power compensation method is proposed for MPDPC to eliminate the DC-side current ripple while maintaining sinusoidal grid current. Besides, to improve the control robustness against mismatched filter inductance, a filter inductance identification scheme is proposed. Through this scheme, the estimated value of filter inductance is updated in each control period and applied in the proposed MPDPC. Finally, simulation results in PSCAD/EMTDC confirm the validity of the proposed MPDPC and the filter inductance identification scheme. | Weichen Yang Shihong Miao Zhiwei Liu Ji Han Yulong Xiong Qingyu Tu | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，6： | 1 |
| 18 | Modi- fication of a theoretical modal for the prediction of thermal expansion behavior of particulate composites: application to poly ( vinyl chloride)/talc composites 显示文摘 | Guangshun Chen Deng Zhiwei Xiong Lei | 2013 | Journal of Macro- molecular Science Part B: Physics2013，52，9： | 1 |
| 19 | One-step preparation of porous aminated-silica nanoparticles and their antibacterial drug delivery applications显示文摘Porous functionalized silica nanoparticles have attracted the interest of researchers as they are excellent carriers for antibacterial drug delivery applications.In this work,porous aminated-silica nanoparticles(SiO2-NH2 NPs) were prepared via one-step approach through the ammonia-catalyzed hydrolysis of tetraethylorthosilicate(TEOS) and(3-aminopropyl) triethoxysilane(APTES) in a mixed water-ethanol system.The obtained SiO2-NH2 NPs displayed a spherical morphology and relatively uniform size distribution,while the morphology and structure of SiO2-NH2 NPs were mainly determined by the order of the reagents added and the pH value of the solution.After characterization,the results showed that there were a large number of-NH2 groups on the surface of porous SiO2-NH2 NPs and that the porous SiO2-NH2 NPs had a large surface area of 476 m2 g-1 with an average pore width of 4.3 nm.Through an absorbing-releasing experiment and bacterial test,those SiO2-NH2 NPs were found to exhibit efficient absorption and release of drugs as well as a pH-de pendent release pattern of epirubicin-loaded SiO2-NH2 NPs.Meanwhile,SiO2-NH2@capsaicin NPs exhibited antibacterial properties.Those porous SiO2-NH2 NPs could be a candidate for drug delivery for antibacterial applications owing to their tailored porous structure and high surface area. | Yongren Wu Shun Chen Yang Liu Zhiwei Lu Shaokun Song Yang Zhang Chuanxi Xiong Lijie Dong | 2020 | Journal of Materials Science & Technology2020，47，15： | 1 |
| 20 | Friction and wear behavior of carbon fiber reinforced lithium aluminosilicate composites sliding against GCr15 steel显示文摘Carbon fibers reinforced lithium aluminosilicate matrix composites(Cf/LAS)were prepared by slurry infiltration combined with a hot press procedure.The friction,wear behavior,and wear mechanisms of Cf/LAS composites under dry sliding conditions were investigated.The results show that the coefficient of friction(COF)initially increased with the increase in carbon fiber content,and reached the maximum value of 0.20 for the 33%Cf/LAS composite.The COF increased sharply with increasing sample temperature from RT to 300℃.The COF remained stable in the temperature range of 300–500℃.The two wear mechanisms of LAS glass-ceramics are fatigue wear and abrasive wear.The Cf/LAS composites demonstrate slight spalling and shallow scratches.These results show that carbon fibers improve the mechanical properties and wear resistance of Cf/LAS composites. | Haibao MA Xin WU Long XIA Longnan HUANG Li XIONG Hua YANG Bo ZHONG Tao ZHANG Zhiwei YANG Feng GAO Guangwu WEN | 2020 | Friction2020，8，6： | 1 |
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