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| 1 | Self-monitoring of blood glucose in type 2 diabetic patients in China:current status and influential factors显示文摘 | Yuan Li Guo Xiaohui Xiong Zhenzhen Lou Qingqing Shen Li Zhao Fang Sun Zilin Li Jianwei | 2014 | Chinese Medical Journal2014,,2: | 21 |
| 2 | Modular growth and clonal propagation of Hippophae rhamnoides subsp, sinensis in response to irrigation intensity显示文摘A multipurpose clone plant species,Hippophae rhamniodes has the capacity for indefinite longevity,although under successive drought stress it may often decline or die across large areas.Field trials were conducted over 2 years to examine the effects of varied irrigation intensities on modular growth and clonal propagation in a semi-arid area.Irrigation levels included a control,as well as two,four and six times the volume of water that was typically received via local annual average precipitation.Irrigation intensity significantly influenced clonal propagation capacity(number of daughter ramets),aboveground modular growth(height,base diameter,and crown width),belowground modular growth included root nodule dry weight,stretching capacity of lateral roots(length of the longest lateral roots,and diameter of firstgrade lateral roots),and branching intensity of lateral roots(number of lateral roots bifurcation grade,number of firstgrade lateral roots).The modular growth and the density of daughter ramets were small under non-irrigation or low irrigation,and became larger with increased irrigation intensity.Beyond a certain threshold,however,further increases in irrigation intensity resulted in a reversion to the development.The optimal irrigation intensities for growth and propagation were 3.48–5.29 times the volume of nominal local annual average precipitation.There were effects of irrigation intensities on the positive significant correlations between aboveground and belowground modular growths,and on clonal propagation capacities.Under various water treatments,H.rhamnoides may adapt to the environment through the regulation of growth and propagation.We concluded that water shortages act to weaken the growth and propagation of H.rhamniodes plantations. | Zilin Cao Tianjiang Li Genqian Li Chunhong Liu Haiyin Gao Guanghui Dai Zhiyong Xiao Sunling Li | 2016 | Journal of Forestry Research2016,27,5: | 14 |
| 3 | Discrete element modeling of ice loads on ship hulls in broken ice fields显示文摘Ice loads on a ship hull affect the safety of the hull structure and the ship maneuvering performance in ice-covered regions.A discrete element method(DEM)is used to simulate the interaction between drifting ice floes and a moving ship.The pancake ice floes are modelled with three-dimensional(3-D)dilated disk elements considering the buoyancy,drag force and additional mass induced by the current.The ship hull is modelled with 3D disks with overlaps.Ice loads on the ship hull are determined through the contact detection between ice floe element and ship hull element and the contact force calculation.The influences of different ice conditions(current velocities and directions,ice thicknesses,concentrations and ice floe sizes)and ship speeds are also examined on the dynamic ice force.The simulated results are compared qualitatively well with the existing field data and other numerical results.This work can be helpful in the ship structure design and the navigation security in ice-covered fields. | JI Shunying LI Zilin LI Chunhua SHANG Jie | 2013 | Acta Oceanologica Sinica2013,32,11: | 12 |
| 4 | Spatial and Temporal Evolution of Surface Subsidence in Tianjin from 2015 to 2020 Based on SBAS-InSAR Technology显示文摘Tianjin is one of the inland cities with the most severe cases of subsidence hazard in China.The majority of the existing studies have mainly focused on Beijing-Tianjin-Hebei,and little attention has been given to Tianjin.In addition,these existing studies are short-term investigations,lacking long-term monitoring of surface subsidence.In the present study,we use the Small Baseline Subset Interferometric Synthetic Aperture Radar(SBAS-InSAR)technique to monitor the subsidence process in Tianjin between 2015 and 2020 and reveal its spatial and temporal variation.We divided the 44-view Sentinel-1A image data into three periods to avoid the effect of temporal and spatial decoherence by extracting the surface deformation field in Tianjin.We finally verified the accuracy and reliability of the inversion results using second-order leveling data.Results showed that the correlation coefficient r between the two reached 0.89,and the root mean square error was 4.84 mm/y.Obvious subsidence funnels exist in Tianjin,mainly in the towns of Wangqingtuo and Shengfang.These subsidence funnels have a subsidence deformation rate of-136.2 mm/y and a maximum cumulative settlement of-346.3 mm within the study period.The subsidence area tends to extend to the southwest.The analysis of annual rainfall,groundwater resource extraction,spatial location distribution of industrial areas combined with SBAS-InSAR inversion results indicates that overextraction of groundwater resources is the main cause of land subsidence in the area.Therefore,strict control of groundwater extraction is the main approach to mitigate land subsidence effectively. | Lyu ZHOU Yizhan ZHAO Zilin ZHU Chao REN Fei YANG Ling HUANG Xin LI | 2022 | Journal of Geodesy and Geoinformation Science2022,5,1: | 8 |
| 5 | Separation,identification,and quantification of active constituents in Fructus Psoraleae by high-performance liquid chromatography with UV,ion trap mass spectrometry,and electrochemical detection显示文摘The qualitative and quantitative analysis of active constituents in Fructus Psoraleae is presented by high-performance liquid chromatography (HPLC) coupled with different detections.Extracts of Fructus Psoraleae were examined by HPLC with ion trap mass spectrometry (IT-MS) and 18 major compounds of coumarins,benzofuran glycosides,flavonoids,and meroterpene were identified.The determination of four major constituents including bavachin,isobavachalcone,bavachinin,and bakuchiol was accomplished by HPLC with UV,MS,and electrochemical detection (ECD).These methods were evaluated for a number of validation characteristics (repeatability,LOD,calibration range,and recovery).ECD obtained a high sensitivity for analysis of the four components;MS provided a high selectivity and sensitivity for determination of bavachin,isobavachalcone,and bavachinin in negative-ion mode.After optimization of the methods,separation,identification.and quantification of the four components in Fructus Psoraleae were comprehensively tested by HPLC with UV,MS,and ECD. | Qinhua Chen,Yuan Li,Zilin Chen Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University),Ministry of Education,and Wuhan University School of Pharmaceutical Sciences,Wuhan,430071,China | 2012 | Journal of Pharmaceutical Analysis2012,2,2: | 7 |
| 6 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016,59,9: | 5 |
| 7 | Process improvement in laser hot wire cladding for martensitic stainless steel based on the Taguchi method显示文摘与低热输入,高精力效率,和高精确的突出的特征,激光热电线 cladding 广泛地被使用因为重新生产的金属分开。然而, cladding 过程需要被使用一个量的方法改善。在这个工作,容量的缺点比率作为标准被建议描述为 cladding 层形成质量的正直。有 FV520B 的激光免职实验, martensitic 不锈钢之一,被使用 Taguchi 方法设计。四个进程变量,也就是激光力量(P) ,扫描速度(V s ), 电线喂率(V f ), 和电线水流(I) ,基于 signal-to-noise (S/N ) 的分析被优化比率。cladding 层的冶金学的观察被进行比较形成的质量并且验证分析方法。有最佳参数联合的稳定、连续的进程与最小的缺点和裂缝生产了一致微观结构,它导致了一个好冶金的结合接口。 | Zilin HUANG Gang WANG Shaopeng WEI Changhong LI Yiming RONG | 2016 | Frontiers of Mechanical Engineering2016,11,3: | 5 |
| 8 | A transient multiphysics coupling method based on OpenFOAM for heat pipe cooled reactors显示文摘Differing from traditional pressurized water reactors(PWRs),heat pipe cooled reactors have the unique characteristics of fuel thermal expansion,expansion reactivity feedback,and thermal contact conductance.These reactors require a new multiphysics coupling method.In this paper,a transient coupling method based on OpenFOAM is proposed.The method considers power variation,thermal expansion,heat pipe operation,thermal contact conductance,and gap conductance.In particular,the reactivity feedback caused by working medium redistribution in a heat pipe is also preliminarily considered.A typical heat pipe cooled reactor KRUSTY(Kilowatt Reactor Using Stirling TechnologY)is chosen as the research object.Compared with experimental results of load following,the calculated results are in good agreement and show the validity of the proposed method.To discuss the self-adjusting capability of this type of reactor system,a hypothetical accident is simulated.It is assumed that at the beginning of this accident,loss of the heat sink occurs.After 1500 s of the transient process,the reactor system recovers immediately.During this hypothetical accident,the control rod is always out of the reactor core,and the reactor only relies on the reactivity feedback to regulate the fission power.According to the simulation,the peak temperature is only about 1112 K,which is far below the safety limit.As for system recovery,the reactor needs approximately 2500 s to return to a steady state and can realize effective power regulation by reactivity feedback.This study confirms the availability of this coupling method and that it can be an effective tool for the simulation of heat pipe cooled reactors. | GUO YuChuan LI ZeGuang WANG Kan SU ZiLin | 2022 | Science China(Technological Sciences)2022,65,1: | 4 |
| 9 | Rejection of insulin therapy among patients with type 2 diabetes in China: reasons and recommendations显示文摘 | Xiong Zhenzhen Yuan Li Guo Xiaohui Lou Qingqing Zhao Fang Shen Li Zhang Mingxia Sun Zilin | 2014 | Chinese Medical Journal2014,,20: | 4 |
| 10 | A Self-supported Graphene/Carbon Nanotube Hollow Fiber for Integrated Energy Conversion and Storage显示文摘Wearable fiber-shaped integrated energy conversion and storage devices have attracted increasing attention,but it remains a big challenge to achieve a common fiber electrode for both energy conversion and storage with high performance.Here,we grow aligned carbon nanotubes(CNTs)array on continuous graphene(G)tube,and their seamlessly connected structure provides the obtained G/CNTs composite fiber with a unique self-supported hollow structure.Taking advantage of the hollow structure,other active materials(e.g.,polyaniline,PANI)could be easily functionalized on both inner and outer surfaces of the tube,and the obtained G/CNTs/PANI composite hollow fibers achieve a high mass loading(90%)of PANI.The G/CNTs/PANI composite hollow fibers can not only be used for high-performance fiber-shaped supercapacitor with large specific capacitance of 472 mF cm^-2,but also can replace platinum wire to build fiber-shaped dye-sensitized solar cell(DSSC)with a high power conversion efficiency of 4.20%.As desired,the integrated device of DSSC and supercapacitor with the G/CNTs/PANI composite hollow fiber used as the common electrode exhibits a total power conversion and storage efficiency as high as 2.1%.Furthermore,the self-supported G/CNTs hollow fiber could be further functionalized with other active materials for building other flexible and wearable electronics. | Kai Liu Zilin Chen Tian Lv Yao Yao Ning Li Huili Li Tao Chen | 2020 | Nano-Micro Letters2020,12,5: | 3 |
| 11 | Simultaneous determination of doxorubicin and its dipeptide prodrug in mice plasma by HPLC with fluorescence detection显示文摘A simple and sensitive high performance liquid chromatography with fluorescence detection(HPLC–FD)has been developed for simultaneous quantification of doxorubicin(DOX) and its dipeptide conjugate prodrug(PDOX) in mice plasma.The chromatographic separation was carried out on an Amethyst C_(18)–H column with gradient mobile phase of 0.1% formic acid and 0.1% formic acid in acetonitrile at a flow rate of 1.0 mL/min.The excitation and emission wavelengths were set at 490 and 550 nm,respectively.The method was comprehensively validated.The limits of detection were low up to 5.0 ng/m L for DOX and 25.0 ng/m L for PDOX.And the limits of quantification were low up to 12.5 ng/m L for DOX and 50 ng/m L for PDOX,which were lower than those for most of the current methods.The calibration curves showed good linearity(R^2>0.999) over the concentration ranges.The extraction recoveries ranged from 84.0% to 88.2% for DOX and from 85.4% to 89.2% for PDOX.Satisfactory intra-day and inter-day precisions were achieved with RSDs less than 9.1%.The results show that the developed HPLC–FD method is accurate,reliable and will be helpful for preclinical pharmacokinetic study of DOX and PDOX. | Jing Han Jue Zhang Haiyan Zhao Yan Li Zilin Chen | 2016 | Journal of Pharmaceutical Analysis2016,6,3: | 3 |
| 12 | Super Na^(+)Half/Full Batteries and Ultrafast Na+Diffusion Kinetics of Cobalt-Nickel Selenide from Assembling Co_(0.5)Ni_(0.5)Se_(2)@NC Nanosheets into Cross-Stacked Architecture显示文摘Explorati on of adva need an ode materials for sodium-i on batteries(SIBs)is still a big challe nge due to the large radius of sodium.In this work,the hierarchical architectures assembled from N-doped carbon-coated Co_(0.5)Ni_(0.5)Se_(2)(Co_(0.5)Ni_(0.5)Se_(2)@NC)nanoparticles encapsulated into cross-stacked nano sheets have been successfully prepared from the cobalt-nickel bin ary-metal organic frameworks(CoNi-MOF)by two steps of the solid-state sele nizati on and carb on coating processes.Imports ntly,the resulta nt hierarchical Co0.5Nio:5Se2@NC architecture can achieve a satisfactory electrochemical performance,maintaining a high-rate capacity of 330 mA-h-g^(-1)1 at 3 A·g^(-1) and a stable cyclability of 100 cycles without obvious capacity decay at 0.2 A·g^(-1).The design of distinct superstructure can not only be applied to other electrode materials but also boost the forward development of energy storage systems. | Zhiyong Li Zilin Peng Rui Sun Zhaoxia Qin Xinlong Liu Caihong Wang Haosen Fan Shengjun Lu | 2021 | Chinese Journal of Chemistry2021,39,9: | 3 |
| 13 | Sex disparity of lung cancer risk in non-smokers:a multicenter population-based prospective study based on China National Lung Cancer Screening Program显示文摘Background: Non-smokers account for a large proportion of lung cancer patients, especially in Asia, but the attention paid to them is limited compared with smokers. In non-smokers, males display a risk for lung cancer incidence distinct from the females-even after excluding the influence of smoking;but the knowledge regarding the factors causing the difference is sparse. Based on a large multicenter prospective cancer screening cohort in China, we aimed to elucidate the interpretable sex differences caused by known factors and provide clues for primary and secondary prevention.Methods: Risk factors including demographic characteristics, lifestyle factors, family history of cancer, and baseline comorbidity were obtained from 796,283 Chinese non-smoking participants by the baseline risk assessment completed in 2013 to 2018. Cox regression analysis was performed to assess the sex difference in the risk of lung cancer, and the hazard ratios (HRs) that were adjusted for different known factors were calculated and compared to determine the proportion of excess risk and to explain the existing risk factors.Results: With a median follow-up of 4.80 years, 3351 subjects who were diagnosed with lung cancer were selected in the analysis. The lung cancer risk of males was significantly higher than that of females;the HRs in all male non-smokers were 1.29 (95% confidence interval [CI]: 1.20-1.38) after adjusting for the age and 1.38 (95% CI: 1.28-1.50) after adjusting for all factors, which suggested that known factors could not explain the sex difference in the risk of lung cancer in non-smokers. Known factors were 7% (|1.29-1.38|/1.29) more harmful in women than in men. For adenocarcinoma, women showed excess risk higher than men, contrary to squamous cell carcinoma;after adjusting for all factors, 47% ([1.30-1.16]/[1.30-1]) and 4% ([7.02-6.75]/[7.02-1])) of the excess risk was explainable in adenocarcinoma and squamous cell carcinoma. The main causes of gender differences in lung cancer risk were lifestyle factors, baseline comorbidity, and family history.Conclusions: Significant gender differences in the risk of lung cancer were discovered in China non-smokers. Existing risk factors did not explain the excess lung cancer risk of all non-smoking men, and the internal causes for the excess risk still need to be explored;most known risk factors were more harmful to non-smoking women;further exploring the causes of the sex difference would help to improve the prevention and screening programs and protect the non-smoking males from lung cancers. | Zheng Wu Fengwei Tan Zhuoyu Yang Fei Wang Wei Cao Chao Qin Xuesi Dong Yadi Zheng Zilin Luo Liang Zhao Yiwen Yu Yongjie Xu Jiansong Ren Jufang Shi Hongda Chen Jiang Li Wei Tang Sipeng Shen Ning Wu Wanqing Chen Ni Li Jie He | 2022 | Chinese Medical Journal2022,,11: | 3 |
| 14 | A modified similitude analysis method for the electro-mechanical performances of a parallel manipulator to solve the control period mismatch problem显示文摘Due to the discrete feature and performance limitation of the numerical controller,the control period sometimes cannot meet the constraints of the scaled model in similitude analysis,which brings the control period mismatch problem.The traditional similitude analysis methods are not able to solve this problem since the controller is treated as continuous system in these methods.This paper proposes a modified similitude analysis method to solve the control period mismatch problem,and the electro-mechanical performances of a 2-DOF parallel manipulator is predicted.Based on the model of dynamic and control system,most of the similitude laws are derived by taking the controller as continuous system.Then the transfer function of the controller in discrete form is established,and the similitude law related to control period is derived to figure out the cause of mismatch problem.The modified method,named long period equivalent,is proposed to solve the mismatch problem by using the least square method and superposition principles.Finally,the scaled model of the parallel manipulator is determined based on the modified similitude analysis method. | WU Jun SONG YuYao LIU ZiLin LI GuoFa | 2022 | Science China(Technological Sciences)2022,65,3: | 3 |
| 15 | Optimal dispatch of multi energy system using power-to-gas technology considering flexible load on user side显示文摘The relation between power-to-gas technology (P2G)and energy interconnection becomes increasingly close.Meanwhile,the participation of flexible load on user side in system optimization has attracted much attention as an efficient approach to relieve the contradiction between energy supply and energy demand.Based on the concept of energy hub,according to its series characteristic,this paper established a generic multi-energy system model using the P2G technology.The characteristic of flexible load on user side was considered and optimal dispatch analysis was made,so as to reduce the cost,to reasonably dispatch the flexible load,to reduce the discharge,to enhance the new energy output,and to increase the power-to-gas conversion efficiency.Finally,a concrete analysis was made on the optimal dispatch result of the multi-energy system using the P2G technology considering flexible load on user side in the calculating example,and optimal dispatch of the system was verified via four different scenarios.The results indicate that cooperative dispatch of multi-energy system using the P2G technology considering flexible load on user side is the most economic,and can make a contribution to absorption of new energy and P2G conversion.In this way,environmental effects and safe and stable operation of the system can be guaranteed. | Zi LING Xiu YANG Zilin LI | 2018 | Frontiers in Energy2018,12,4: | 3 |
| 16 | Anti-fatigue activity of Brassica rapa L.extract and correlation among biochemical changes in forced swimming mice显示文摘Brassica rapa L.is an edible and medical plant in China used for treating various diseases,especially in the Tibet region.In this study,the chemical constituents of Brassica rapa L.extract(BE)was clarified by UHPLC-MS and anti-fatigue ability of BE was assessed through the behavior test and weight-loaded forced swimming test in mice.Then we determined several biochemical parameters related to fatigue to explore possible reasons.Results indicate that BE could significantly enhance exercise performance in mice,and there was a significant improvement in both grip-strength and the time on rota-rods.Meanwhile,BE showed significant anti-fatigue effects by decreasing the blood lactic acid(BLA),blood urea nitrogen(BUN),and creatine kinase(CK)levels and increasing the lactate dehydrogenase(LDH)and malondialdehyde(MDA)levels.Increases in superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)were observed and reactive oxygen species(ROS)levels was regulated.Liver and muscle glycogen levels and adenosine triphosphate(ATP)levels were also significantly increased.Pearson correlation analysis indicates that fatigue-related indexes including metabolites and energy-related indexes were significantly correlated with antioxidant levels.In conclusion,BE possesses remarkable anti-fatigue activity,thereby shows great potential for improving exercise performance and alleviating physical fatigue and can be considered as a functional food supplement for further development. | Zilin Li Hongkang Zhu Hanyi Hua Chang Liu Yuliang Cheng Yahui Guo Peng Du He Qian | 2022 | Food Bioscience2022,47,3: | 2 |
| 17 | Recent advances in nonlinear optics for bio‐imaging applications显示文摘Nonlinear optics,which is a subject for studying the interaction between intense light and materials,has great impact on various research fields.Since many structures in biological tissues exhibit strong nonlinear optical effects,nonlinear optics has been widely applied in biomedical studies.Especially in the aspect of bio-imaging,nonlinear optical techniques can provide rapid,label-free and chemically specific imaging of biological samples,which enable the investigation of biological processes and analysis of samples beyond other microscopy techniques.In this review,we focus on the introduction of nonlinear optical processes and their applications in bio-imaging as well as the recent advances in this filed.Our perspective of this field is also presented. | Silu Zhang Liwei Liu Sheng Ren Zilin Li Yihua Zhao Zhigang Yang Rui Hu Junle Qu | 2020 | Opto-Electronic Advances2020,3,10: | 2 |
| 18 | Determining similarity between concepts in corpus显示文摘 | Chen Li Song Zilin Miao Zhuang | 2012 | Lecture Notes in Electrical Engineering2012,113,: | 1 |
| 19 | Mining association rules based on cloud model显示文摘 | Du Yi Song Zilin Li Deyi | 2000 | Journal of PLA University of Science and Technology2000,1,1: | 1 |
| 20 | Determination of bavachin and isobavachalcone in Fructus Psoraleae by high-performance liquid chromatography with electrochemical detection 显示文摘 | Li Yuan Wang Fang Chen Zilin | 2011 | J Sep Sci2011,34,: | 1 |