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1Effect of coal levels during direct reduction roasting of high phosphorus oolitic hematite ore in a tunnel kiln显示文摘The effect of coal levels on phosphorus removal from a high phosphorus oolitic hematite ore after direct reduction roasting have been investigated. Raw ore, coal, and a dephosphorization agent were mixed and the mixture was then roasted in a tunnel kiln. The roasted products were treated by two stages of grinding followed by magnetic separation. XRD and SEM-EDS examination of the products was used to analyze differences in the roasted products. The results show that coal is one of the most important factors affecting the direct reduction roasting process. When the inner coal levels increased from 0% to 15% the iron grade decreased linearly from 94.94% to 88.81% and the iron recovery increased from 55.94% to 92.94%. At the same time the phosphorus content increased from 0.045% to 0.231%. Increasing the inner coal levels also caused more hematite to be reduced to metallic iron but the oolitic structure of the roasted product was preserved in the presence of high coal loading. The phase of the phosphorus in raw ore was not changed after direct reduction roasting. The effect of coal on the phosphorus content in the H-concentrate arises from changes in the difficulty of mechanically liberating the metallic iron from the phosphorus bearing minerals.Li Yongli Sun Tichang Zou Anhua Xu Chengyan 2012International Journal of Mining Science and Technology2012,22,3:22
2Efficacy and safety of metformin and sitagliptin based triple antihyperglycemic therapy(STRATEGY):a multicenter,randomized,controlled,non-inferiority clinical trial显示文摘Despite the current guideline's recommendation of a timely stepwise intensification therapy,the 'clinical inertia',termed as the delayed treatment intensification,commonly exists in the real world,which may be partly due to the relatively little substantial evidence and no clear consensus regarding the efficacy and safety of triple oral agents in patients inadequately controlled with dual therapy.In this clinical trial performed in 237 centers in China,5,535 type 2 diabetic patients inadequately controlled by previous therapies were treated with a stable metformin/sitagliptin dual therapy for 20 weeks.The patients who did not reach the glycated hemoglobin A1c(HbA1c) goal were then further randomized into glimepiride,gliclazide,repaglinide,or acarbose group for an additional 24-week triple therapy.A mean HbAlc reduction of 0.85%was observed when sitagliptin was added to the patients inadequately controlled with metformin in 16 weeks.Further HbAlc reductions in the 24-week triple therapy stage were 0.65%in glimepiride group,0.70%in gliclazide group,0.61%in repaglinide group,and 0.45%in acarbose group.The non-inferiority criterion for primary hypotheses was met for gliclazide and repaglinide,but not for acarbose,compared with glimepiride,when added to metformin/sitagliptin dual therapy.The incidences of adverse events(AEs) were 29.2%in the dual therapy stage and30.3%in the triple therapy stage.Metformin/sitagliptin as baseline therapy,with the addition of a third oral antihyperglycemic agent,including glimepiride,gliclazide,repaglinide,or acarbose,was effective,safe and well-tolerated for achieving an HbAlc<7.0%goal in type 2 diabetic patients inadequately controlled with previous therapies.The timely augmentation of up to three oral antihyperglycemic agents is valid and of important clinical benefit to prevent patients from exposure to unnecessarily prolonged hyperglycemia.Wen Xu Yiming Mu Jiajun Zhao Dalong Zhu Qiuhe Ji Zhiguang Zhou Bin Yao Anhua Mao Samuel S.Engel Bin Zhao Yan Bi Longyi Zeng Xingwu Ran Juming Lu Linong Ji Wenying Yang Weiping Jia Jianping Weng 2017Science China(Life Sciences)2017,60,3:19
3A multicenter hospital-based diagnosis study of automated breast ultrasound system in detecting breast cancer among Chinese women显示文摘Objective: The automated breast ultrasound system(ABUS) is a potential method for breast cancer detection;however, its diagnostic performance remains unclear. We conducted a hospital-based multicenter diagnostic study to evaluate the clinical performance of the ABUS for breast cancer detection by comparing it to handheld ultrasound(HHUS) and mammography(MG).Methods: Eligible participants underwent HHUS and ABUS testing; women aged 40–69 years additionally underwent MG. Images were interpreted using the Breast Imaging Reporting and Data System(BI-RADS).Women in the BI-RADS categories 1–2 were considered negative. Women classified as BI-RADS 3 underwent magnetic resonance imaging to distinguish true-and false-negative results. Core aspiration or surgical biopsy was performed in women classified as BI-RADS 4–5, followed by a pathological diagnosis. Kappa values and agreement rates were calculated between ABUS, HHUS and MG.Results: A total of 1,973 women were included in the final analysis. Of these, 1,353(68.6%) and 620(31.4%)were classified as BI-RADS categories 1–3 and 4–5, respectively. In the older age group, the agreement rate and Kappa value between the ABUS and HHUS were 94.0% and 0.860(P<0.001), respectively; they were 89.2% and0.735(P<0.001) between the ABUS and MG, respectively. Regarding consistency between imaging and pathology results, 78.6% of women classified as BI-RADS 4–5 based on the ABUS were diagnosed with precancerous lesions or cancer; which was 7.2% higher than that of women based on HHUS. For BI-RADS 1–2, the false-negative rates of the ABUS and HHUS were almost identical and were much lower than those of MG.Conclusions: We observed a good diagnostic reliability for the ABUS. Considering its performance for breast cancer detection in women with high-density breasts and its lower operator dependence, the ABUS is a promising option for breast cancer detection in China.Xi Zhang Xi Lin Yanjuan Tan Ying Zhu Hui Wang Ruimei Feng Guoxue Tang Xiang Zhou Anhua Li Youlin Qiao 2018Chinese Journal of Cancer Research2018,30,2:13
4Role of in-situ formed free carbon on electromagnetic absorption properties of polymer-derived SiC ceramics显示文摘In order to enhance dielectric properties of polymer-derived SiC ceramics,a novel single-source-precursor was synthesized by the reaction of an allylhydrido polycarbosilane(AHPCS)and divinyl benzene(DVB)to form carbon-rich SiC.As expected,the free carbon contents of resultant SiC ceramics annealed at 1600℃are significantly enhanced from 6.62 wt%to 44.67 wt%.After annealing at 900-1600℃,the obtained carbon-rich SiC ceramics undergo phase separation from amorphous to crystalline feature where superfine SiC nanocrystals and turbostratic carbon networks are dispersed in an amorphous SiC(O)matrix.The dielectric properties and electromagnetic(EM)absorption performance of as-synthesized carbon-rich SiC ceramics are significantly improved by increasing the structural order and content of free carbon.For the 1600℃ ceramics mixed with paraffin wax,the minimum reflection coefficient(RCmin)reaches-56.8 dB at 15.2 GHz with the thickness of 1.51 mm and a relatively broad effective bandwidth(the bandwidth of RC values lower than-10 dB)of 4.43 GHz,indicating the excellent EM absorption performance.The carbon-rich SiC ceramics have to be considered as harsh environmental EM absorbers with excellent chemical stability,high temperature,and oxidation and corrosion resistance.Zhaoju YU Xuan LV Kangwei MAO Yujing YANG Anhua LIU 2020Journal of Advanced Ceramics2020,9,5:5
5DESCRIPTION AND PREDICTION OF CATASTROPHE OF VIBRATION STATE FOR FAULTY ROTORS显示文摘A sudden increase of vibration amplitude with no foreboding often results in an abrupt breakdown of a mechanical system.The catastrophe of vibration state of a faulty rotor is a typical nonlinear phenomenon,and very difficult to be described and predicted with linear vibration theory.On the basis of nonlinear vibration and catastrophe theory,fhe eatastrophe of the vibration amplitude of the faulty rotor is described;a way to predict its emergence is developed.Chen Anhua Zhong Jue 1996Transactions of Nonferrous Metals Society of China1996,6,1:5
6CitGVD:a comprehensive database of citrus genomic variations显示文摘Citrus is one of the most important commercial fruit crops worldwide.With the vast genomic data currently available for citrus fruit,genetic relationships,and molecular markers can be assessed for the development of molecular breeding and genomic selection strategies.In this study,to permit the ease of access to these data,a web-based database,the citrus genomic variation database(CitGVD,http://citgvd.cric.cn/home)was developed as the first citrusspecific comprehensive database dedicated to genome-wide variations including single nucleotide polymorphisms(SNPs)and insertions/deletions(INDELs).The current version(V1.0.0)of CitGVD is an open-access resource centered on 1,493,258,964 high-quality genomic variations and 84 phenotypes of 346 organisms curated from in-house projects and public resources.CitGVD integrates closely related information on genomic variation annotations,related gene annotations,and details regarding the organisms,incorporating a variety of built-in tools for data accession and analysis.As an example,CitGWAS can be used for genome-wide association studies(GWASs)with SNPs and phenotypic data,while CitEVOL can be used for genetic structure analysis.These features make CitGVD a comprehensive web portal and bioinformatics platform for citrus-related studies.It also provides a model for analyzing genome-wide variations for a wide range of crop varieties.Qiang Li Jingjing Qi Xiujuan Qin Wanfu Dou Tiangang Lei Anhua Hu Ruirui Jia Guojin Jiang Xiuping Zou Qin Long Lanzhen Xu Aihong Peng Lixiao Yao Shanchun Chen Yongrui He 2020Horticulture Research2020,7,1:4
7Dependence of magnetic properties on microstructure and composition of Ce-Fe-B sintered magnets显示文摘In this paper,dependence of magnetic properties on microstructure and composition of Ce-Fe-B sintered magnets with Cu-doped Ce-rich alloy addition was investigated.It shows that the maximum energy product(BH)(max)and coercivity H(cj)of Ce-Fe-B sintered magnet are improved from 6.76 to 9.13 MGOe by 35.1%,and from 1.44 to 1.67 kOe by 16.0%,respectively,via adding 5 wt%liquid phase alloy of Ce(35.58)Fe(57.47)Cu6 B(0.95)(at%).Compared with the magnet without Cerich alloy addition,the volume fraction of the grain-boundary phase with low melting point increases in the magnet with Ce-rich alloy additio n,which is be ne ficial to imp roving the microstructure and promoting the coercivity enhancement of the magnet.In the Ce-Fe-B magnet with Ce-rich alloy addition,Cu and Ce enrich in the grain boundaries of the magnet after annealing,therefore the as-annealed magnet has a higher coercivity than the as-sintered magnet.A distinct Fe-rich layer with the average thickness of 60 nm is found in the grain boundaries in the magnet without Ce-rich alloy addition,but it seems that Fe-rich phase disappears in the magnet with Ce-rich alloy addition.The present work suggests that the further improvement of coercivity in the Ce-Fe-B sintered magnets is expectable by designing the composition and structure of added liquid phase alloys.Longlong Xi Anhua Li Haibo Feng Min Tan Wei Sun Minggang Zhu Wei Li 2019Journal of Rare Earths2019,37,8:4
8LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells显示文摘LIN28 is an RNA binding protein with important roles in early embryo development,stem cell differentiation/re-programming,tumorigenesis and metabolism.Previous studies have focused mainly on its role in the cytosol where it interacts with Let-7 microRNA precursors or mRNAs,and few have addressed LIN28's role within the nucleus.Here,we show that LIN28 displays dynamic temporal and spatial expression during murine embryo development.Maternal LIN28 expression drops upon exit from the 2-cell stage,and zygotic LIN28 protein is induced at the forming nucleolus during 4-cell to blas-tocyst stage development,to become dominantly expressed in the cytosol after implantation.In cultured pluripotent stem cells(PSCs),loss of LIN28 led to nucleolar stress and activation of a 2-cell/4-cell-like transcriptional program characterized by the expression of endogenous retrovirus genes.Mechanistically,LIN28 binds to small nucleolar RNAs and rRNA to maintain nucleolar integrity,and its loss leads to nucleolar phase separation defects,ribosomal stress and activation of P53 which in turn binds to and activates 2C transcription factor Dux.LIN28 also resides in a complex containing the nucleolar factor Nucleolin(NCL)and the transcrip-tional repressor TRIM28,and LIN28 loss leads to reduced occupancy of the NCL/TRIM28 complex on the Dux and rDNA loci,and thus de-repressed Dux and reduced rRNA expression.Lin28 knockout cells with nucleolar stress are more likely to assume a slowly cycling,translationally inert and anabolically inactive state,which is a part of previously unappreciated 2C-like transcriptional program.These findings elucidate novel roles for nucleolar LIN28 in PSCs,and a new mechanism linking 2C program and nucleolar functions in PSCs and early embryo development.Zhen Sun Hua Yu Jing Zhao Tianyu Tan Hongru Pan Yuqing Zhu Lang Chen Cheng Zhang Li Zhang Anhua Lei Yuyan Xu Xianju Bi Xin Huang Bo Gao Longfei Wang Cristina Correia Ming Chen Qiming Sun Yu Feng Li Shen Hao Wu Jianlong Wang Xiaohua Shen George Q.Daley Hu Li Jin Zhang 2022Protein & Cell2022,13,7:4
9Core competence evaluation standards for emergency nurse specialist: Developing and testing psychometric properties显示文摘Introduction:Nurse specialists are being cultivated and trained in China to cope with the international development of nursing discipline.However,an empirical summary and reviews of literature have shown a lack of core competence evaluation standards for emergency nurse specialists(ENSs)in China.ENS training has been conducted in several regions without any effective competence evaluation standards.This paper describes the development and psychometric testing of the Core Competence Evaluation Standards for Emergency Nurse Specialists(CCESENS)in the Chinese context.Methods:Several rigorous research methods were applied.The proposed evaluation process consisted of two phases with seven steps.First,the Core Competence Framework Model for Emergency Nurse Specialist(CCFMENS)was established,and 118 items were generated through a review of literature,theoretical analysis,and expert interviews.Drafts of the dimensions and items were evaluated by two-round Delphi methods.Analysis hierarchy process was used to determine the weight of each dimension.Second,field testing was performed among 138 senior emergency nurses.Internal consistency and correlation analysis were applied to test the reliability and validity of the model.Results:The CCESENS consisted of five first-level dimensions,16 second-level dimensions,and 55 items.Cronbach's a coefficient of overall standards was 0.972,and each dimension ranged from 0.508 to 0.972.Expert content validity index was 0.818,and the correlation coefficients of the five first-level dimensions with the overall standards CCESENS ranged from 0.701 to 0.886(P<0.05).Discussion:The CCESENS demonstrated sound internal consistency reliability,content validity,and construct validity.The proposed standard provides an objective standard and reference for assessing,training,and evaluating core competence of ENS.Luo Fan Li Gui Shuhua Xi Anhua Qiao 2016International Journal of Nursing Sciences2016,3,3:3
10CsWAKL08,a pathogen-induced wall-associated receptor-like kinase in sweet orange,confers resistance to citrus bacterial canker via ROS control and JA signaling显示文摘Citrus bacterial canker(CBC)is a disease resulting from Xanthomonas citri subsp.citri(Xcc)infection and poses a grave threat to citrus production worldwide.Wall-associated receptor-like kinases(WAKLs)are proteins with a central role in resisting a range of fungal and bacterial diseases.The roles of WAKLs in the context of CBC resistance,however,remain unclear.Here,we explored the role of CsWAKL08,which confers resistance to CBC,and we additionally analyzed the molecular mechanisms of CsWAKL08-mediated CBC resistance.Based on systematic annotation and induced expression analysis of the CsWAKL family in Citrus sinensis,CsWAKL08 was identified as a candidate that can be upregulated by Xcc infection in the CBC-resistant variety.CsWAKL08 can also be induced by the phytohormones salicylic acid(SA)and methyl jasmonic acid(MeJA)and spans the plasma membrane.Overexpression of CsWAKL08 resulted in strong CBC resistance in transgenic sweet oranges,whereas silencing of CsWAKL08 resulted in susceptibility to CBC.The peroxidase(POD)and superoxide dismutase(SOD)activities were significantly enhanced in the CsWAKL08-overexpressing plants compared to the control plants,thereby mediating reactive oxygen species(ROS)homeostasis in the transgenic plants.Moreover,the JA levels and the expression of JA biosynthesis and JA responsive genes were substantially elevated in the CsWAKL08 overexpression plants relative to the controls upon Xcc infection.Based on these findings,we conclude that the wall-associated receptor-like kinase CsWAKL08 positively regulates CBC resistance through a mechanism involving ROS control and JA signaling.These results further highlight the importance of this kinase family in plant pathogen resistance.Qiang Li Anhua Hu Jingjing Qi Wanfu Dou Xiujuan Qin Xiuping Zou Lanzhen Xu Shanchun Chen Yongrui He 2020Horticulture Research2020,7,1:3
11Systematic reviews on reports of hip fractures in Web of Science:a bibliometric analysis of publication activity显示文摘Mao Zhi Wang Guoqi Mei Xifan Chen Shuo Liu Xiaoxie Zeng Xiantao Long Anhua Zhang Licheng Zhang Lihai Tang Peifu 2014Chinese Medical Journal2014,,13:2
12Optical and scintillation properties of Ce:Y_(3)Al_(5)O_(12) single crystal fibers grown by laser heated pedestal growth method显示文摘The single crystal scintillating optical fibers acting as the scintillators and light conductors show potential application in scintillating fiber array detectors with high spatial resolution.In this paper we report the growth of 0.2 at%Ce:Y_(3)Al_(5)O_(12) single crystal fiber.The crystalline phase,surface morphology of the axialsection and cro ss-section,optical and scintillation properties of the as-grown fiber were investigated.The Ce:Y_(3)Al_(5)O_(12) single crystal fiber has a pure YAG phase,a uniform distribution of cerium in the axialsection and cross-section surface.Emission spectrum is composed of broad bands ranging from 440 to700 nm.In addition,the single crystal fiber has a high light yield of 26115±2000 photons/MeV,low energy resolution of 9.44%@662 keV and decay time of a fast component of 78 ns and a slow component of 301 ns.The intensity ratio of fast to slow components is roughly 8:1.Xibin Wang Yun Dai Zhonghan Zhang Liangbi Su Huamin Kou Yangxiao Wang Anhua Wu 2021Journal of Rare Earths2021,39,12:2
13Reinforcement effects of ground treatment with dynamic compaction replacement in cold and saline soil regions显示文摘The mechanical property of saline soils varies with moisture and climate in the cold and salt lake region of Qinghai-Tibet Plateau, which influences project construction. In order to improve foundation reinforcement effect of the Qarhan-Golmud Highway, Qinghai Province, China, dynamic compaction replacement (DCR) composite foundation was applied in saline soils. A field experiment was conducted in this area, where strength and working mechanism of pier-soil and deformation modulus of the composite foundation was analyzed after reinforcement. This paper presents methods for determining the coefficient on the bearing capacity evaluation and deformation modulus of composite foundation with DCR. Reinforcement case of DCR is highly effective in saline soils of the salt lake regions, which helps the migration of water and salt in saline soils.Yu Zhang JianKun Liu JianHong Fang AnHua Xu 2013Research in Cold and Arid Regions2013,5,4:2
14Environmentally benign chemical fixation of CO_(2) catalyzed by the functionalized ion-exchange resins显示文摘Basic ion-exchange resins,one kind of polystyryl-supported tertiary amine,were demonstrated to be highly efficient and recyclable catalysts for the fixation of carbon dioxide with aziridines under mild conditions,leading to the formation of 5-aryl-2-oxazolidinone with excellent regio-selectivities.Notably,neither solvents nor any additives were required,and the catalyst could be recovered by simple filtration and directly reused at least five times without significant loss of catalytic activity and selectivity.The present protocol has been applied to reactions of epoxides/propargyl amines with CO_(2)/CS2.This solvent-free process thus represents environmentally friendly catalytic conversion of CO_(2) into value-added chemicals and may have potential in various continuous flow reactors in industry.LIU AnHua HE LiangNian PENG ShiYong PAN ZhongDa WANG JingLun GAO Jian 2010Science China Chemistry2010,53,7:2
15Pomegranate-type Si/C anode with SiC taped,well-dispersed tiny Si particles for lithium-ion batteries显示文摘Severe volume expansion and inherently poor lithium ion transmission are two major problems of silicon anodes.To address these issues,we proposed a pomegranate-type Si/C composite anode with highly dispersed tiny silicon particles as the core assisted by small amount of SiC.Skillfully exploiting the high heat from magnesiothermic reduction,SiC can assist the good dispersion of silicon and provide good interface compatibility and chemical stability.The silicon anchored to the carbon shell provides multipoint contact mode,that together with the carbon shell frame,significantly promoting the transfer of dual charge.Besides,the pomegranate-type microcluster structure also improves the tap density of the electrode,reduces the direct contact area between active material and electrolyte,and enhances the electrochemical performance.Pengfei WU Benyang SHI Huibin TU Changqing GUO Anhua LIU Guan YAN Zhaoju YU 2021Journal of Advanced Ceramics2021,10,5:2
16Temperature monitoring of the XPS board insulated subgrade along the newly constructed Gonghe-Yushu Highway in permafrost regions显示文摘On the basis of on-site measured data of the newly constructed Gonghe-Yushu Highway in a permafrost region, this paper analyzed thermal conditions of the subgrade with XPS insulated board according to different selected monitoring sections in various locations. We also summarized the geothermal distribution and change rules of subgrade with XPS insulation board under the asphalt pavement in summarized a high temperature frozen soil region. It is suggested that the shoulder of subgrade with XPS insulation board be widen to a reasonable width so as to keep the subgrade stable.BoWen Tai JianHong Fang Lei Liu AnHua Xu JianKun Liu Ya Hu Tian 2015Research in Cold and Arid Regions2015,7,5:2
17Analysis of eighty-one cases with breast lesions using automated breast volume scanner and comparison with handheld ultrasound显示文摘Xi Lin Jianwei Wang Feng Han Jianhua Fu Anhua Li 2011European Journal of Radiology2011,,5:2
18Determination of estrogens in human urine by high-performance liquid chromatography/diode array detec- tion with ultrasound-assisted cloud-point extraction显示文摘Zou Yan Li anhua Jin Hua 2012Anal Biochem2012,421,2:1
19Flame-retardant ep- oxy resin from a caged bicyclic phosphate quadridentate sili- con complex 显示文摘Zhang Lili Liu Anhua Zeng Xingrong 2008Journal of Applied Polymer Science2008,,1:1
20Localized and Sustained Delivery of Erythropoietin from PLGA Microspheres Promotes Functional Recovery and Nerve Regeneration in Peripheral Nerve Injury显示文摘Wei Zhang Yuan Gao Yan Zhou Jianheng Liu Licheng Zhang Anhua Long Lihai Zhang Peifu Tang Ali I. Abdalla 2015BioMed Research International2015,,:1
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