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| 1 | Construction and Functional Analysis of a Lentiviral Expression Vector Containing a Scavenger Receptor (SR-PSOX) that Binds Uniquely Phosphatidylserine and Oxidized Lipoprotein显示文摘这研究的目的是构造包含特别地绑与的 scavenger 受体(SR-PSOX ) 的 lentiviral 表达式向量有六个 histidine 标签并且到的 phosphatidylserine 和氧化脂蛋白在动脉粥样硬化调查 SR-PSOX 的函数。我们利用有效在 vitro 或 invivo 交付目标基因进用提高的 biosafetyreplication 无能的 lentivirus 划分和非划分的哺乳动物的房间的 ViraPower lentiviral 表达式系统。钝结束的顺序用克隆反应的 reversetranscription 聚合酶链反应和方向性的 TOPO 被放大。通过一双 thecytomegalovirus 提交教材和 SR-PSOX 的反向的教材,正确克隆被聚合酶链反应识别并且定序。包装混合 andSR-PSOX-pLenti6/V5 TOPO 表示原生质标志的 ViraPower 是进 293FT 房间线 usingLipofectamine 的 co-transfected 2000。内长、外长的 SR-PSOX 以及在在不同时间的各种各样的泡沫房间模型的 - α蛋白质削尖的肿瘤坏死因素(TNF ) 的表示被 sodiumdodecyl sulfate-polyacrylamide 凝胶电泳,蛋白质印迹和间接 immunofluorescenceassay 检测。蛋白质印迹和免疫荧光分析证实α蛋白质是起来的 SR-PSOX andTNF- 的表情在泡沫房间模型调整了。我们的数据建议过去表示 ofrecom-binant 人 SR-PSOX 蛋白质能支持泡沫房间形成并且起来调整煽动性的因素 TNF- α的表示。 | Zhihua QUAN Huiling YANG Yongzong YANG Bin YAN Renxian CAO Gebo WEN Changhui LIU Yangyan XU | 2007 | Acta Biochimica et Biophysica Sinica2007，39，3： | 16 |
| 2 | Selective laser melting of NiTi alloy with superior tensile property and shape memory effect显示文摘It is a challenge to develop complex-shaped Ni Ti shape memory alloy parts by traditional processing methods, due to the poor machinability of Ni Ti alloy. It is reported that selective laser melting(SLM) of additive manufacturing could overcome this problem. However, the reported SLM-produced Ni Ti exhibits poor tensile ductility due to the inner defects and adverse unidirectional columnar grains from SLM process. In this work, the defect-less SLM-Ni Ti with nondirective columnar grains was fabricated by optimizing the intraformational laser scanning length and interformational laser scanning direction. The obtained lath-shaped SLM-Ni Ti sample exhibits tensile strain of 15.6%, more than twice of the reported maximum result(7%). Besides, the SLM-Ni Ti part with complex geometry displays a shape memory recovery of 99% under compressive deformation of 50%. | Zhiwei Xiong Zhonghan Li Zhen Sun Shijie Hao Ying Yang Meng Li Changhui Song Ping Qiu Lishan Cui | 2019 | Journal of Materials Science & Technology2019，35，10： | 15 |
| 3 | Gold nanoflowers for 3D volumetric molecular imaging of tumors by photoacoustic tomography显示文摘By binding molecular probes that target tumor cells, gold nanoparticles (AuNPs) with superior characteristics have shown great potential in tumor molecular imaging studies. The non-invasive, high-resolution, and three-dimensional imaging of the targeted AuNPs within the tumor is desirable for both diagnosis and therapy. In this study, gold nanoflowers (AuNFs) are presented as a novel contrast agent for photoacoustic tomography (PAT). By binding to folic acid, the molecular probe, the tail-vein injected AuNFs concentrated within the tumor site in mice; this was clearly visualized by three-dimensional (3D) PAT imaging. In addition, toxicity assay proved that AuNFs were harmless to living cells and animals. Our results demonstrate that AuNFs have great potential in tumor molecular imaging. | Yuanyuan Jiang Zijian Deng Dan Yang Xin Deng Qi Li Yinlin Sha Changhui Li Dongsheng Xu | 2015 | Nano Research2015，8，7： | 8 |
| 4 | First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2]. | ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，10： | 6 |
| 5 | Processing and mechanical properties of 2024 aluminum matrix composites containing Tungsten and Tantalum prepared by PM显示文摘The 2024 Al composites containing W, Ta were fabricated by powder metallurgy for their potential use as shielding material. W, Ta powders and gas-atomized 2024 Al aluminum powders were mixed by a ball mixer. The mixtures were consolidated by cold isostatic pressing (CIP) and then hot-extruded into full-density bars. The extruded bars were heat treated in T6 conditions. The microstructure and its relationship with the mechanical properties were investigated by means of scanning electron microscopy (SEM) and X-ray diffraction (XRD). The results show that the particles of nonuniform size and irregular shape randomly disperse in the 2024 aluminum alloy matrix. The tensile tests show that an increase of tensile strength and decrease of elongation to failure of the heat treated composites compared with the extruded composites. | LIAN Youyun YANG Zhimin YANG Jian MAO Changhui | 2006 | Rare Metals2006，25，z2： | 4 |
| 6 | Integrating a model with remote sensing observations by a data assimilation approach to improve the model simulation accuracy of carbon flux and evapotranspiration at two flux sites显示文摘Model simulation and in situ observations are often used to research water and carbon cycles in terrestrial ecosystems, but each of these methods has its own advantages and limitations. Combining these two methods could improve the accuracy of quantifying the dynamics of the water and carbon fluxes of an ecosystem. Data assimilation is an effective means of integrating modeling with in situ observation. In this study, the ensemble Kalman filter(En KF) and the unscented Kalman filter(UKF) algorithms were used to assimilate remotely sensed leaf area index(LAI) data with the Biome-BGC model to simulate water and carbon fluxes at the Harvard Forest Environmental Monitoring Site(EMS) and the Dinghushan site. After MODIS LAI data from 2000–2004 were assimilated into the improved Biome-BGC model using the En KF algorithm at the Harvard Forest site, the R2 between the simulated and observed results for NEE and evapotranspiration increased by 7.8% and 4.7%, respectively. In addition, the sum of the absolute error(SAE) and the root mean square error(RMSE) of NEE decreased by an average of 21.9% and 26.3%, and the SAE and RMSE of evapotranspiration decreased by 24.5% and 25.5%, respectively. MODIS LAI data of 2003 were assimilated into the Biome-BGC model for the Dinghushan site, and the R2 values between the simulated and observed results for NEE and evapotranspiration were increased by 6.7% and 17.3%, respectively. In addition, the SAE values of NEE and ET were decreased by 11.3% and 30.7%, respectively, and the RMSE values of NEE and ET decreased by 10.1% and 30.9%, respectively. These results demonstrate that the accuracy of carbon and water flux simulations can be effectively improved when remotely sensed LAI data are properly integrated with ecosystem models through a data assimilation approach. | ZHANG TingLong SUN Rui PENG ChangHui ZHOU GuoYi WANG ChunLing ZHU QiuAn YANG YanZheng | 2016 | Science China Earth Sciences2016，59，2： | 3 |
| 7 | EAST-Educational Adaptive-optics Solar Telescope显示文摘For the public having a better understanding of solar activities,the Educational Adaptive-optics Solar Telescope(EAST)was built in July 2021 and is located at the Shanghai Astronomy Museum.The EAST consists of a 65 cm aperture solar telescope with a 177-element adaptive optics system and two-channel high resolution imaging system at the Hαand TiO bands,in addition to three full disk solar telescopes at CaK,Hαand TiO bands equipped on the tube of the main telescope.In this paper,the configuration of the EAST is described.Its performance and on-sky observational results are presented.The EAST,to our knowledge,is the most advanced solar telescope for the popularization of science in the world.Due to its excellent performance,the data acquired by the EAST can also be used for research on solar physics and space weather prediction. | Changhui Rao Xuejun Rao Zhimao Du Hua Bao Cheng Li Jinlong Huang Youming Guo Libo Zhong Qing Lin Xin Ge Jinsheng Yang Xinlong Fan Yangyi Liu Dan Jia Xin Li Mei Li Ming Zhang Yuntao Cheng Jiahui Zhou Jiawen Yao Lanqiang Zhang Naiting Gu | 2022 | Research in Astronomy and Astrophysics2022，22，6： | 3 |
| 8 | Ligand-Controlled Copper-Catalyzed Highly Regioselective Difluoromethylation of Allylic Chlorides/Bromides and Propargyl Bromides显示文摘高度 regiodivergent 由采用不同 ligands 的催化铜的 allylic/propargylic difluoromethylation 反应被描述。当 5,6-dimethyl-1,10-phenanthroline 被用作 ligand 时,只, -difluoromethylated 产品被获得,当当 N 杂环的 carbene-SIPr 被用作 ligand 时,选择 difluoromethylated 产品被产生时。同样,高 - 对选择为 propargyl 溴化物的反应面对类似的铜催化剂被完成。而且,催化铜的不对称的 allylic difluoromethylation 反应与对由 chiral ligands 的使用的好 enantioselectivity 中等被开发。 | Yang Gu Changhui Lu Yucheng Gu Qilong Shen | 2018 | Chinese Journal of Chemistry2018，36，1： | 3 |
| 9 | NiO nanoparticle-decorated SnO_(2)nanosheets for ethanol sensing with enhanced moisture resistance显示文摘In a high relative humidity(RH)environment,it is challenging for ethanol sensors to maintain a high response and excellent selectivity.Herein,tetragonal rutile SnO_(2)nanosheets decorated with NiO nanoparticles were synthesized by a two-step hydrothermal process.The NiO-decorated SnO_(2)nanosheet-based sensors displayed a significantly improved sensitivity and excellent selectivity to ethanol gas.For example,the 3 mol%NiO-decorated SnO_(2)(SnO_(2)-3Ni)sensor reached its highest response(153 at 100 ppm)at an operating temperature of 260℃.Moreover,the SnO_(2)-3Ni sensor had substantially improved moisture resistance.The excellent properties of the sensors can be attributed to the uniform dispersion of the NiO nanoparticles on the surface of the SnO_(2)nanosheets and the formation of NiO-SnO_(2)p–n heterojunctions.Considering the long-term stability and reproducibility of these sensors,our study suggests that the NiO nanoparticle-decorated SnO_(2)nanosheets are a promising material for highly efficient detection of ethanol. | Gaoqiang Niu Changhui Zhao Huimin Gong Zhitao Yang Xiaohui Leng Fei Wang | 2019 | Microsystems & Nanoengineering2019，5，1： | 3 |
| 10 | Advances and challenges on springback control for creep age forming of aluminum alloy显示文摘Creep age forming(CAF)is an advanced forming technology that combines creep deformation and age hardening processes.When compared with the conventional forming technologies including roll bending and shot-peen forming,CAF has many advantages of low residual stress,excellent dimensional stability,good service performance and short production cycle.It is an optimal technique for precise manufacturing for shape and properties of large-scale complicated thinwalled components of light-weight and high strength aluminum alloys in the aviation and aerospace industries.Nevertheless,CAF has an inevitable disadvantage that a large amount of springback occurs after unloading,which brings a challenge on the accurate shape forming and property tailoring of components.Therefore,how to achieve accurate prediction and control of springback has always been a bottleneck hindering the development of CAF to more industrial applications.After the factors of affecting springback and measures of reducing springback are summarized from the internal and external aspects,constitutive models for predicting springback and springback compensation methods for CAF of aluminum alloy panel components are reviewed.Then,a review of research progresses on tool design for CAF is presented.Finally,in view of the key issue that it is difficult to predict and control the shape and properties of components during CAF,the technical challenges are discussed and future development trends of CAF are prospected. | Liwen ZHANG Heng LI Tianjun BIAN Changhui WU Yang GAO Chao LEI | 2022 | Chinese Journal of Aeronautics2022，35，10： | 3 |
| 11 | Regeneration and identification of interspecific asymmetric somatic hybrids obtained by donor-recipient fusion in cotton显示文摘Asymmetric hybrids between Gossypium hirsutum (YZ-1) and G. davidsonii were obtained by donor-recipient fusion. YZ-1 was considered the recipient and was pretreated with iodoacetamide (IOA), while G. davidsonii was considered the donor and was irradiated with ultraviolet (UV) before fusion. YZ-1 protoplasts stopped growth when treated with 0.5 mmol/L IOA for 20 min, and G. davidsonii protoplasts stopped growth when irradiated with 38.7 J/cm2 UV for 30 s. Asymmetric somatic hybrids were obtained by electrofusion between the separately treated protoplasts of the 2 species. The regenerated plants were identified by morphological, cytological, and molecular analysis. Most regenerated plants derived from fused protoplasts displayed new morphology; some were intermediate between the two parents and a few displayed recipient-like morphology. Chromosome numbers in these somatic hybrids mostly ranged from 40 to 73. The hybridity was confirmed by random amplified polymorphic DNA and simple sequence repeat analysis. Organelle DNA inheritance of the YZ-1 and G. davidsonii somatic hybrid was investigated by cleaved amplified polymorphism sequence and chloroplast simple sequence repeat analysis, which indicated that recombination and rearrangements might have occurred in some regions of mitochondrial and chloroplastic DNA. This is the first report of completely asymmetric hybrid production via donor–recipient fusion between G. hirsutum and G. davidsonii, which is a novel case in hybrid production following the symmetric fusion and asymmetric fusion based on UV irradiation in cotton. | FU LiLi YANG XiYan ZHANG XianLong WANG ZhiWei FENG ChangHui LIU ChuanXiang JIANG Pei-Yong ZHANG JinLong | 2009 | Chinese Science Bulletin2009，54，17： | 3 |
| 12 | Microstructure and Mechanical Properties of AlSi10Mg Alloy Manufactured by Laser Powder Bed Fusion Under Nitrogen and Argon Atmosphere显示文摘In order to study the effect of gas atmosphere on forming performance of laser powder bed fusion(LPBF),AlSi10 Mg alloy was prepared by direct forming and in situ laser remelting under the shielding gas of argon and nitrogen in this study,and its micro structure and properties were characterized and tested,respectively.The results show that the forming performance of AlSi10 Mg under nitrogen atmosphere is better than that of argon.Moreover,in situ laser remelting method can effectively enhance the relative density and mechanical properties of AlSi10 Mg,in which the densification is increased to 99.5%.In terms of mechanical properties,after in situ remelting,ultimate tensile strength under argon protection increased from444.85±8.73 to 489.45±3.20 MPa,and that under nitrogen protection increased from 459.21±13.77 to 500.14±5.15 MPa.In addition,the elongation is nearly doubled and the micro-Vickers hardness is increased by 20%.The research results provide a new regulation control method for the customization of AlSi10 Mg properties fabricated by LPBF. | Yunmian Xiao Yongqiang Yang Shibiao Wu Jie Chen Di Wang Changhui Song | 2022 | Acta Metallurgica Sinica(English Letters)2022，35，3： | 2 |
| 13 | DEAP1 encodes a fasciclin-like arabinogalactan protein required for male fertility in rice显示文摘Arabinogalactan proteins(AGPs)are widely distributed in plant cells.Fasciclin-like AGPs(FLAs)belong to a subclass of AGPs that play important roles in plant growth and development.However,little is known about the biological functions of rice FLA.Herein,we report the identification of a male-sterile mutant of DEFECTIVE EXINE AND APERTURE PATTERNING1(DEAP1)in rice.The deap1 mutant anthers produced aberrant pollen grains with defective exine formation and a flattened aperture annulus and exhibited slightly delayed tapetum degradation.DEAP1 encodes a plasma membrane-associated member of groupⅢplant FLAs and is specifically and temporally expressed in reproductive cells and the tapetum layer during male development.Gene expression studies revealed reduced transcript accumulation of genes related to exine formation,aperture patterning,and tapetum development in deap1 mutants.Moreover,DEAP1 may interact with two rice D6 PROTEIN KINASE-LIKE3 s(OsD6PKL3s),homologs of a known Arabidopsis aperture protein,to affect rice pollen aperture development.Our findings suggested that DEAP1 is involved in male reproductive development and may affect exine formation and aperture patterning,thereby providing new insights into the molecular functions of plant FLAs in male fertility. | Dan Zhou Ting Zou Kaixuan Zhang Pingping Xiong Fuxing Zhou Hao Chen Gongwen Li Kaiyou Zheng Yuhao Han Kun Peng Xu Zhang Shangyu Yang Qiming Deng Shiquan Wang Jun Zhu Yueyang Liang Changhui Sun Xiumei Yu Huainian Liu Lingxia Wang Ping Li Shuangcheng Li | 2022 | Journal of Integrative Plant Biology2022，64，7： | 2 |
| 14 | Developing optofluidic technology through the fusion of microfluidics and optics显示文摘 | Psaltis D Quake S R Yang Changhui | 2006 | Nature2006，442，27： | 1 |
| 15 | Enhanced antibacterial activity of silica nanorattles with ZnO combination nanoparticles against methicillin-resistant Staphylococcus aureus显示文摘Silica nanorattles(SNs) with zinc oxide(ZnO) combination nanoparticles are reported to inhibit methicillin-resistant Staphylococcus aureus(MRSA) for the first time. SNs loaded with ZnO nanoparticles,which can produce free radicals, can cause severe damage to bacteria. ZnO nanoparticles not only provide free radicals in the combined nanostructures, which can inhibit the growth of bacteria, but also form nanorough surfaces with an irregular distribution of spikes on the SNs, which can enhance their adhesion to bacteria. Nanorough silica shell surfaces maintain the high activity and stability of small-sized ZnO nanoparticles and gather ZnO nanoparticles together to enhance production, which improves the efficiency of free radicals against the cytomembranes of bacterial cells. The enhanced adhesion of ZnO@SN nanoparticles to MRSA cells shortens the effective touching distance between free radicals and MRSA, which also improves antibacterial activity. As we expected, the ZnO@SN nanoparticles exhibit a better antibacterial effect than free ZnO nanoparticles against MRSA in vitro and in vivo. We also demonstrate that SNs loaded with ZnO nanoparticles can accelerate wound healing in MRSA skin inflammation models. This method of multilevel functionalization will be potentially applicable to the antibacterial field. | Qianqian Chai Qiong wu Tianlong Liu Longfei Tan Changhui Fu Xiangling Ren Yue Yang Xianwei Meng | 2017 | Science Bulletin2017，62，17： | 1 |
| 16 | Preparation of ultra-high performance concrete with common technology and materials显示文摘 | Chong Wang Changhui Yang Fang Liu | 2012 | Cement concrete composites2012，，34： | 1 |
| 17 | Clinical Study of the Necessity of Replanning Before the 25th Fraction During the Course of Intensity-Modulated Radiotherapy for Patients With Nasopharyngeal Carcinoma显示文摘 | Wei Wang Haihua Yang Wei Hu Guoping Shan Weijun Ding Changhui Yu Biyun Wang Xufeng Wang Qianyi Xu | 2010 | International Journal of Radiation Oncology Biology Physics2010，，2： | 1 |
| 18 | Preparation of ultra-high performance concrete with common technology and materials显示文摘 | Wang Chong Yang Changhui Liu Fang | 2012 | Cement and Concrete Composites2012，34，4： | 1 |
| 19 | Bit-error rate for free-space optical communication with tip-tilt compensation显示文摘 | Changqi Yang Wenhan Jiang Changhui Rao | 2006 | Waves in Random and Complex Media2006，16，3： | 1 |
| 20 | Ground-layer adaptive optics for the New Vacuum Solar Telescope:Instrument description and first results显示文摘Ground-layer adaptive optics(GLAO)has shown its potential for use in solar observation owing to its wide field-of-view(FOV)correction.A high-order GLAO system that consists of a multiple direction Shack-Hartmann wavefront sensor(WFS),a realtime controller with a multi-CPU processor,and a 151-element deformable mirror was developed for the 1-m New Vacuum Solar Telescope at Yunnan Observatories,Chinese Academy of Sciences.A hexagonal microlens with 9×8 subapertures is employed in the WFS.The detection FOV is 42′′×37′′,in which 9(3×3)guide regions are extracted for multiple direction wavefront sensing with a frame rate of up to 2200 Hz.To our knowledge,this is the first professional solar GLAO system used as a regularly operating instrument for scientific observations.Its installation and adjustment were performed in the summer of 2021.In this article,a detailed account of the GLAO system and its first light results and a comprehensive analysis of the performance of the GLAO system are provided.The results show that this system can effectively improve the imaging quality after compensating for the wavefront aberration due to ground-layer turbulence. | Lanqiang Zhang Hua Bao Xuejun Rao Youming Guo Libo Zhong Xian Ran Nanfei Yan Jinsheng Yang Cheng Wang Jiahui Zhou Ying Yang Yunyao Long Xinlong Fan Zhongyi Feng Donghong Chen Changhui Rao | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，6： | 1 |
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