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| 1 | Characterization of red mud derived from a combined Bayer Process and Calcining method for alumina refining显示文摘 | Chuxia LIN Yonggui LIU | 2006 | Chinese Journal Of Geochemistry2006,25,B08: | 5 |
| 2 | Competitive removal of water-borne copper, zinc and cadmium by a CaCO3-dominated red mud显示文摘 | Ma Yingqun Lina Chuxia Jiang Yuehua | 2009 | Journal of Hazardous Materials2009,172,: | 1 |
| 3 | Inhibition of aberrant Hif1αactivation delays intervertebral disc degeneration in adult mice显示文摘The intervertebral disc(IVD) is the largest avascular tissue. Hypoxia-inducible factors(HIFs) play essential roles in regulating cellular adaptation in the IVD under physiological conditions. Disc degeneration disease(DDD) is one of the leading causes of disability, and current therapies are ineffective. This study sought to explore the role of HIFs in DDD pathogenesis in mice. The findings of this study showed that among HIF family members, Hif1α was significantly upregulated in cartilaginous endplate(EP) and annulus fibrosus(AF) tissues from human DDD patients and two mouse models of DDD compared with controls. Conditional deletion of the E3 ubiquitin ligase Vhl in EP and AF tissues of adult mice resulted in upregulated Hif1α expression and age-dependent IVD degeneration. Aberrant Hif1α activation enhanced glycolytic metabolism and suppressed mitochondrial function. On the other hand, genetic ablation of the Hif1α gene delayed DDD pathogenesis in Vhl-deficient mice. Administration of 2-methoxyestradiol(2ME2), a selective Hif1α inhibitor, attenuated experimental IVD degeneration in mice. The findings of this study show that aberrant Hif1α activation in EP and AF tissues induces pathological changes in DDD, implying that inhibition of aberrant Hif1α activity is a potential therapeutic strategy for DDD. | Zuqiang Wang Hangang Chen Qiaoyan Tan Junlan Huang Siru Zhou Fengtao Luo Dali Zhang Jing Yang Can Li Bo Chen Xianding Sun Liang Kuang Wanling Jiang Zhenhong Ni Quan Wang Shuai Chen Xiaolan Du Di Chen Chuxia Deng Liangjun Yin Lin Chen Yangli Xie | 2022 | Bone Research2022,10,1: | 1 |
| 4 | Characterization of red mud derived from a combined Bayer process and bauxite calcinations method显示文摘 | LIU Yong LIN Chuxia WU Yonggui | 2007 | Journal of Hazardous Materials2007,146,12: | 1 |
| 5 | Essential Role of Smad3 in Angiotensin II–Induced Vascular Fibrosis显示文摘 | Wansheng Wang Xiao R. Huang Ellery Canlas Kazuhiro Oka Luan D. Truong Chuxia Deng Neil A. Bhowmick Wenjun Ju Erwin P. Bottinger Hui Y. Lan | 2006 | Circulation Research2006,,8: | 1 |
| 6 | Mice lacking p21ciol/WAF1 undergo normal development, but are defective in G1 checkpoint 显示文摘 | Sherr C J Morrison A | 1995 | Cell1995,82,: | 1 |
| 7 | Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth显示文摘 | Chuxia Deng Anthony Wynshaw-Boris Fen Zhou Ann Kuo Philip Leder | 1996 | Cell1996,,6: | 1 |
| 8 | Characterization of red mud derived from a combined bayer process and bauxite cal- cinations method显示文摘 | Liu Yong Lin Chuxia Wu Yong | 2007 | J Hazard Mater2007,146,12: | 1 |
| 9 | Physiological, biochemical and growth responses of Italian ryegrass to butachlor exposure显示文摘 | Shaorui Wang Huashou Li Chuxia Lin | 2013 | 2013 (1-2)2013,,1: | 1 |
| 10 | Defective FGF signaling causes coloboma formation and disrupts retinal neurogenesis显示文摘眼的裂缝() 在将近所有网膜的祖先房间区别发生了以前,是关门的发展中的脊椎动物眼睛的腹的方面上的短暂开始。关上 OF 的失败导致 coloboma,是童年盲目的一个主要原因的先天的疾病。尽管人的基因研究和动物模型连接了很多基因到 coloboma,驾驶 OF 的闭合的细胞、分子的机制大部分仍然是不清楚的。在这研究,我们使用了 Cre-LoxP-mediated 成纤维细胞生长的有条件的移动因素(FGF ) 受体, Fgfr1 和 Fgfr2,从发展,眼的杯(OC ) 调整关门 OF 显示出发信号的那 FGF。我们的分子,细胞并且 Fgfr1 和 Fgfr2 的 transcriptome 分析加倍有条件的猛烈 OC 建议发信号的 FGF 通过网膜的祖先房间增长,命运说明和词法变化的调整控制 OF 闭合。而且, Fgfr1 和 Fgfr2 加倍房间没能开始网膜的中心房间(RGC ) 的有条件的变异的网膜的祖先开始。一起拿,我们基因研究揭示的鼠标发信号的那 FGF 是必要的为形态发生和 RGC 开发。 | Shuyi Chen Hua Li Karin Gaudenz Ariel Paulson Fengli Guo Rhonda Trimble Allison Peak Christopher Seidel Chuxia Deng Yasuhide Furuta Ting Xie | 2013 | Cell Research2013,23,2: | 1 |
| 11 | Plant uptake and in-soil degradation of PCB-5 under varying cropping conditions显示文摘 | Li Huashou Liu Longyuan Lin Chuxia | | 0,,84: | 1 |
| 12 | Characterization of red mud derived from a combined bayer process and bauxite calcination method显示文摘 | Liu Yong Lin Chuxia Wu Yonggui | 2007 | J Hazard Mater2007,146,12: | 1 |
| 13 | Competitive removal of water-borne copper, zinc and cadmium by a CaCO 3 -dominated red mud显示文摘 | Yingqun Ma Chuxia Lin Yuehua Jiang Wenzhou Lu Chunhua Si Yong Liu | 2009 | Journal of Hazardous Materials2009,,2: | 1 |
| 14 | Characterization of red mud derived from a combined Bayer process and bauxite calcinations method显示文摘 | LIU YONG LIN CHUXia WU YONG | 2007 | Journal of Hazardous Materials2007,146,12: | 1 |
| 15 | Can rainwater induce Fenton-driven degradation of herbicides in natural waters?显示文摘 | Junhao Qin Huashou Li Chuxia Lin Gu Chen | 2013 | Chemosphere2013,,8: | 1 |
| 16 | Characterization of red mud derived rom a combined Bayer Process and bauxite calcination method 显示文摘 | Liu Yong Lin Chuxia Wu Yonggui | 2007 | J Hazard Mater2007,146,12: | 1 |
| 17 | Visible light and base promoted O-H insertion/cyclization of para-quinone methides with aryl diazoacetates: An approach to 2,3-dihydrobenzofuran derivatives显示文摘A visible light and base promoted O-H insertion/cyclization of para-quinone methides with aryl diazoacetates is developed. This one-pot two step reaction offers a mild and efficient approach for the synthesis of biologically important 2,3-dihydrobenzofuran derivatives in good yields and moderate diastereoselectivities. | Shuangjing Zhou Baogui Cai Chuxia Hu Xu Cheng Lei Li Jun Xuan | 2021 | Chinese Chemical Letters2021,32,8: | 0 |
| 18 | Human Influences on the Development of Acid Sulphate Soils in the Pearl River (the Zhujiang) Delta显示文摘HumanInfluencesontheDevelopmentofAcidSulphateSoilsinthePearlRiver(theZhujiang)Delta¥LINCHUXIA(choolOfGeography,TheUniversityo... | LIN CHUXIA(chool Of Geography, The University of New South Wales, Sydney, N. S. W. 2052 (Australia)) | 1996 | Pedosphere1996,6,1: | 0 |
| 19 | Impacts of acid mine drainage on a stream in subtropical China during a major flood event显示文摘 | Chuxia LIN Yonggui WU Wenzhou LU Aisheng CHEN Yong LIU | 2006 | Chinese Journal Of Geochemistry2006,25,B08: | 0 |
| 20 | Transformation and immobilization of hexavalent chromium in the co-presence of biochar and organic acids:effects of biochar dose and reaction time显示文摘A batch experiment was conducted to examine the effects of biochar dose and reaction duration on the transformation and immobilization of Cr(VI)in the combined biochar and low-molecular-weight organic acid systems.The results showed that increase in the dosage level of biochar caused increase in the solution pH,particularly for the Biochar300 treatments but did not enhance the reduction of Cr(VI)after 1-day reaction.Over 35%of the converted Cr(III)was immobilized by sorption to the biochar due to increased negatively charged sites on the biochar surfaces driven by pH rise.The elevated pH due to biochar dose increase tended to slow down the reduction of Cr(VI)to Cr(III),resulting in more Cr(VI)being adsorbed at a higher biochar dose.For the higher-temperature biochars,the increase in biochar dose did not markedly change the transformation and immobilization of the added Cr.Increase in the reaction duration markedly increased the pH for Biochar300.This resulted in the disappearance of all Cr(VI)in the solution after the 7-day reaction,possibly through sorption of cationic Cr(III)to the biochar surfaces.Increase in reaction time for the higher-temperature biochars resulted in re-oxidation of Cr(III)to Cr(VI)due to the increased exposure of solution Cr(III)to atmospheric oxygen.The research findings obtained from this study have implications for optimizing treatment procedure for wastewater that contains elevated level of toxic Cr(VI).Simulation experiments are required to determine appropriate biochar dose and reaction time to achieve cost-effective treatment goals. | Yongjun Li Wenming Xiong Xin Wei Junhao Qin Chuxia Lin | 2021 | Biochar2021,3,4: | 0 |