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| 1 | Genetic diversity and construction of core collection in Chinese wheat genetic resources显示文摘Genetic diversity among 5029 accessions representing a proposed Chinese wheat core collection was analyzed using 78 pairs of fluorescent microsatellite (SSR) primers mapped to 21 chromosomes. A stepwise hierarchical sampling strategy with priority based on 4×105 SSR data-points was used to construct a core collection from the 23090 initial collections. The core collection consisted of 1160 accessions, including 762 landraces, 348 modern varieties and 50 introduced varieties. The core ac-counts for 23.1% of the 5029 candidate core accessions and 5% of the 23090 initial collections, but retains 94.9% of alleles from the candidate collections and captures 91.5% of the genetic variation in the initial collections. These data indicate that it is possible to maintain genetic diversity in a core collection while retaining fewer accessions than the accepted standard, i.e., 10% of the initial collections captured more than 70% of their genetic diversity. Estimated genetic representation of the core con-structed by preferred sampling (91.5%) is much higher than that by random sampling (79.8%). Both mean genetic richness and genetic diversity indices of the landraces were higher than those of the modern varieties in the core. Structure and principal coordinate analysis revealed that the landraces and the modern varieties were two relatively independent subpopulations. Strong genetic differentiation associated with ecological environments has occurred in the landraces, but was relatively weak in the modern cultivars. In addition, a mini-core collection was constructed, which consisted of 231 accessions with an estimated 70% representation of the genetic variation from the initial collections. The mini-core has been distributed to various research and breeding institutes for detailed phenotyping and breeding of genetic introgression lines. | HAO ChenYang DONG YuChen WANG LanFen YOU GuangXia ZHANG HongNa GE HongMei JIA JiZeng ZHANG XueYong | 2008 | Chinese Science Bulletin2008，53，10： | 27 |
| 2 | Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta显示文摘胎盘为成功的怀孕和胎儿和怀孕女人的健康是关键的。然而,人的 trophoblast 系怎么被调整,包括胎盘的房间的分类,子类型糟糕被理解。这里,我们在排序的胎盘的房间上执行了定序的单个房间的 RNA (RNA-seq ) 从第一三个月并且秒三个月人胎盘。已知的 cytotrophoblast 房间(CTB ) 的房间的新子类型, extravillous trophoblast 房间(EVT ) , Hofbauer 房间,和间充质的 stromal 房间被识别, cell-type-specific 基因签名被定义。机能上地,这研究揭示了人的胎盘的许多以前未知的功能。尤其是, 102 多肽荷尔蒙基因被发现被胎盘的房间的各种各样的子类型表示,它在调整母亲的生理学的胎儿的生长和改编到怀孕建议建筑群和这些荷尔蒙的重要角色。这些结果在单个房间的分辨率记录人的胎盘的 trophoblast 区别并且因此在怀孕的早阶段期间推进我们人的胎座式的理解。 | Yawei Liu Xiaoying Fan Rui Wang Xiaoyin Lu Yan-Li Dang Huiying Wang Hai-Yan Lin Cheng Zhu Hao Ge James C. Cross Hongmei Wang | 2018 | Cell Research2018，28，8： | 15 |
| 3 | Response of phytoliths in Leymus chinensis to the simulation of elevated global CO_2 concentrations in Songnen Grassland,China显示文摘Measuring the response of terrestrial ecosystems to elevated CO2 concentrations is very important for understanding the effects of global change. In this study,OTC (open top chambers) were used to simulate elevated CO2 concentrations in the Songnen Grass-land. As well,phytoliths in Leymus chinensis were extracted to study the relationships between phytoliths and CO2 concentration. The results show the rondel is abundant in Leymus chinensis,while the trapeziform polylobate is rare. When phytolith production is increased,the rondel phytoliths grow bigger and the proportions of the different phytolith types changes under high CO2 concentration. These types include elongate hollow,acicular hair cell,square and laminate and are only observed in samples grown under high CO2 concentrations. All this evidence demonstrates that phytoliths in Leymus chinensis are sensitive to CO2 concentration,and indicate that phytolith analysis may have potential use in the study of global change,identifying different ecotypes of Leymus chinensis and for the reconstruction of paleoatmospheric CO2 concentrations. | GE Yong JIE DongMei GUO JiXun LIU HongMei SHI LianXuan | 2010 | Chinese Science Bulletin2010，55，32： | 14 |
| 4 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 5 | The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis显示文摘 | Fang Wang Wei Song Hongmei Zhao Yanni Ma Yuxia Li Di Zhai Jingnan Pi Yanmin Si Jiayue Xu Lei Dong Rui Su Mengmeng Zhang Yong Zhu Xiaoxia Ren Fei Miao Wenjie Liu Feng Li Junwu Zhang Aibin He Ge Shan Jingyi Hui Linfang Wang Jia Yu | 2017 | Cell Research2017，27，3： | 7 |
| 6 | Characteristics of phytoliths in Leymus chinensis from different habitats on the Songnen Plain in Northeast China and their environmental implications显示文摘The characteristics of phytoliths in Leymus chinensis leaves from five different pH-value habitats from Songnen Plain in China were analyzed to reveal their environmental implications and possible use for quantitative reconstruction of the paleoenvironment. The phytoliths in leaves of L. chinensis from the five habitats showed a non-linear correlation with soil pH. The main types of phytoliths from the different habitats were exactly the same, including silicified stomata, hat-shaped, lanceolate, elongated, multilateral-plate, and tooth-shaped. However, there were significant differences in the contents of each shape of phytoliths among the five habitats. The amount and the volume of weakly tooth-shaped, lanceolate phytoliths and silicified stomata increased with increased pH, while the total amount of phytoliths was reduced. In addition, there were different types of phytoliths in the L. chinensis leaves from the five habitats of different pH, suggesting that the types of phytoliths were controlled, at least in part, by soil pH. The changes of size and percentage of phytoliths were most remarkable at pH 10.15–10.18, indicating that this is the highest pH value that L. chinensis can tolerate. | JIE DongMei LIU ZhaoYang SHI LianXuan LIU HongMei GE Yong | 2010 | Science China Earth Sciences2010，53，7： | 6 |
| 7 | Expert consensus on early childhood caries management显示文摘Early childhood caries(ECC)is a significant chronic disease of childhood and a rising public health burden worldwide.ECC may cause a higher risk of new caries lesions in both primary and permanent dentition,affecting lifelong oral health.The occurrence of ECC has been closely related to the core microbiome change in the oral cavity,which may be influenced by diet habits,oral health management,fluoride use,and dental manipulations.So,it is essential to improve parental oral health and awareness of health care,to establish a dental home at the early stage of childhood,and make an individualized caries management plan.Dental interventions according to the minimally invasive concept should be carried out to treat dental caries.This expert consensus mainly discusses the etiology of ECC,caries-risk assessment of children,prevention and treatment plan of ECC,aiming to achieve lifelong oral health. | Jing Zou Qin Du Lihong Ge Jun Wang Xiaojing Wang Yuqing Li Guangtai Song Wei Zhao Xu Chen Beizhan Jiang Yufeng Mei Yang Huang Shuli Deng Hongmei Zhang Yanhong Li Xuedong Zhou | 2022 | International Journal of Oral Science2022，14，3： | 5 |
| 8 | A haplotype block associated with thousand-kernel weight on chromosome 5DS in common wheat(Triticum aestivum L.)显示文摘Spike number per unit area, number of grains per spike, and thousand-kernel weight(TKW) are important yield components for wheat(Triticum aestivum L.). TKW has the highest heritability among the three components. We validated 27 simple sequence repeat(SSR) loci associated with TKW in an F2:5breeding population grown in four environments. A cfd78265 bpmarker on chromosome 5DS showed the strongest association with TKW and had a significantly positive effect on TKW compared to allele cfd78259 bp, with mean increases of 5.17, 3.63, 4.11, and 5.16 g in the four environments. Markers cfd67 and cfd40 flanking cfd78 also showed significantly positive associations with TKW with increases of 5.11, 3.29, 4.31, and 4.50 g for cfd67205, and4.98, 3.49, 4.06, and 4.84 g for cfd40187 compared with cfd67203 and cfd40190in the four environments, respectively. A major quantitative trait locus for TKW spanning 2.94 c M on chromosome 5DS was detected by association mapping.Strong linkage disequilibrium(LD)(r2> 0.2) was detected Resear among the three linked markers, which formed three haplotype blocks in the F2:5breeding population. Mean TKW differences between Hap B-I and Hap B-II were 5.80, 4.41, 4.02,and 5.06 g in the four environments, respectively. Moreover,significant LD was detected only between cfd78 and cfd67 and between cfd67 and cfd40 in a germplasm collection. This study provides a base for cloning genes related to TKW on chromosome 5DS. | Yuquan Wang Chenyang Hao Jun Zheng Hongmei Ge Yang Zhou Zhengqiang Ma Xueyong Zhang | 2015 | Journal of Integrative Plant Biology2015，57，8： | 5 |
| 9 | Oxygen-vacancy-rich TiO_(2)enables highly active and durable water electrolysis of urchin-like RuO_(2)catalyst显示文摘The material innovation is prerequisite to accelerating sluggish oxygen evolution reaction(OER)kinetics,thus promoting the realization of hydrogen energy community.Herein,we develop an oxygen-vacancy-rich TiO_(2)supported RuO_(2)catalyst(RuO_(2)@r-TiO_(2))towards improved OER activity and stability.The oxygen vacancy on TiO_(2)not only supplies electrons to produce lower valence Ru,but also provides sufficient anchoring site for the deposition of RuO_(2)nanocrystal.Beyond that,it can generate strong electronic interaction between TiO_(2)and supported RuO_(2),and thereby tailors the intermediates’adsorption energy on the RuO_(2)surface.As a result,the derived RuO_(2)@r-TiO_(2)catalyst exhibits superior OER activity and stability with the overpotential of 211 mV at a current density of 10 mA cm^(−2)and negligible activity degradation after 6 h operation,outperforming the non-oxygen-vacancy counterpart(223.3 mV,12.75%activity loss)and RuO_(2)catalyst(234.6 mV,42.86%activity loss). | GAO HongMei XIAO MeiLing LI GuoQiang GAO LiQin MENG QingLei LUO ZhaoYan LUO ErGui LIU ChangPeng JIN Zhao GE JunJie XING Wei | 2022 | Science China(Technological Sciences)2022，65，10： | 3 |
| 10 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 11 | Study on the co-luminescence system Sm-Gd-BPMPHD-CTMAB and its analytical application显示文摘 | Jinghe Yang Hongmei Ge Nianqin Jie Xuozhen Ren Naixing Wang Huabin Zou | 1994 | Fresenius’ Journal of Analytical Chemistry (-)1994，，10： | 1 |
| 12 | Antidiabetic drug metformin alleviates endotoxin-induced fulminant liver injury in mice显示文摘 | Hongmei Yuan Longjiang Li Weiping Zheng Jingyuan Wan Pu Ge Hongzhong Li Li Zhang | 2012 | International Immunopharmacology2012，，4： | 1 |
| 13 | Genome-wide signatures of the geographic expansion and breeding of soybean显示文摘Soybean is a leguminous crop that provides oil and protein. Exploring the genomic signatures of soybean evolution is crucial for breeding varieties with improved adaptability to environmental extremes. We analyzed the genome sequences of 2,214 soybeans and proposed a soybean evolutionary route, i.e., the expansion of annual wild soybean(Glycine soja Sieb. & Zucc.) from southern China and its domestication in central China, followed by the expansion and local breeding selection of its landraces(G. max(L.) Merr.). We observed that the genetic introgression in soybean landraces was mostly derived from sympatric rather than allopatric wild populations during the geographic expansion. Soybean expansion and breeding were accompanied by the positive selection of flowering time genes, including GmSPA3c. Our study sheds light on the evolutionary history of soybean and provides valuable genetic resources for its future breeding. | Ying-Hui Li Chao Qin Li Wang Chengzhi Jiao Huilong Hong Yu Tian Yanfei Li Guangnan Xing Jun Wang Yongzhe Gu Xingpeng Gao Delin Li Hongyu Li Zhangxiong Liu Xin Jing Beibei Feng Tao Zhao Rongxia Guan Yong Guo Jun Liu Zhe Yan Lijuan Zhang Tianli Ge Xiangkong Li Xiaobo Wang Hongmei Qiu Wanhai Zhang Xiaoyan Luan Yingpeng Han Dezhi Han Ruzhen Chang Yalong Guo Jochen C.Reif Scott A.Jackson Bin Liu Shilin Tian Li-juan Qiu | 2023 | Science China(Life Sciences)2023，66，2： | 1 |
| 14 | The luminescence system of yttrium(Ⅲ)-BPMPHD-CTMAB and the determination of yttrium(Ⅲ) 显示文摘 | Yang Jinghe Ge Hongmei Ren Xuezhen | 1994 | Talanta1994，41，12： | 1 |
| 15 | Research on automatic for identification technology by meteorological satellite remotesensing显示文摘 | Zhou Hongmei Ge Weiqiang Bai Hua | 2009 | Journal of Tropical Meteorology2009，4，1： | 1 |
| 16 | Effect of light intensity on bound EPS characteristics of two Microcystis morphospecies:the role of bEPS in the proliferation of Microcystis显示文摘Bound extracellular polymeric substances(bEPS)play an important role in the proliferation of Microcystis.However,the understanding of bEPS characterization remains limited.In this study,threedimensional fluorescence excitation-emission matrix(3D-EEM)spectroscopy and zeta potentiometer were used to characterize the loosely bound EPS(LB-EP S)and tightly bound EPS(TB-EPS)from two dominant Microcystis morphospecies from Taihu Lake(China)at different light intensities.Physiochemical analysis showed that the growth and TB-EPS or bEPS contents in Microcystis aeruginosa were higher than those in Microcystisfl os-aquae at each light intensity.The 3D-EEM contour demonstrated that the intensities of peak B(tryptophan-like substances)in the TB-EPS from M.aeruginosa were stronger than those from M.flosaquae when the light intensity was higher than 10μE/(m^(2)·s).Zeta potential analysis showed that the absolute values of the zeta potential of TB-EPS in the two species both increased with rising light intensity,except those of TB-EPS in M.aeruginosa at 105μE/(m^(2)·s).Moreover,the absolute values of the zeta potential of M.aeruginosa were higher than tho se of M.flos-aquae at each light intensity.All these re sults indicated that M.aeruginosa may more quickly proliferate than M.flos-aquae through increased negative charges,bEPS contents.growth.and tryptophan-like substance contents at certain light intensities. | Xianzhe WANG Xingye HAN Hongmei GE | 2022 | Journal of Oceanology and Limnology2022，40，5： | 1 |
| 17 | A TEMPOL and rapamycin loaded nanofiber-covered stent favors endothelialization and mitigates neointimal hyperplasia and local inflammation显示文摘An increased level of reactive oxygen species(ROS)plays a major role in endothelial dysfunction and vascular smooth muscle cell(VSMC)proliferation during in-stent thrombosis and restenosis after coronary artery stenting.Herein,we report an electrospun core-shell nanofiber coloaded with 4-hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl(TEMPOL)and rapamycin(RAPA)that correspondingly serves as an ROS scavenger and VSMC inhibitor.This system has the potential to improve the biocompatibility of current drug-eluting stent(DES)coatings with the long-term and continuous release of TEMPOL and rapamycin.Moreover,the RAPA/TEMPOL-loaded membrane selectively inhibited the proliferation of VSMCs while sparing endothelial cells(ECs).This membrane demonstrated superior ROS-scavenging,anti-inflammatory and antithrombogenic effects in ECs.In addition,the membrane could maintain the contractile phenotype and mitigate platelet-derived growth factor BB(PDGF-BB)-induced proliferation of VSMCs.In vivo results further revealed that the RAPA/TEMPOL-loaded covered stents promoted rapid restoration of vascular endothelium compared with DES and persistently impeded inflammation and neointimal hyperplasia in porcine models. | Rui Wang Jian Lu Jiasheng Yin Han Chen Hongmei Liu Fei Xu Tongtong Zang Rende Xu Chenguang Li Yizhe Wu Qilin Wu Xiang Fei Meifang Zhu Li Shen Junbo Ge | 2023 | Bioactive Materials2023，，1： | 1 |
| 18 | Graphene incorporated nanocrystalline TiO 2 films for the photocathodic protection of 304 stainless steel显示文摘 | Xingqin Guo Wei Liu Lixin Cao Ge Su Hongmei Xu Binhao Liu | 2013 | Applied Surface Science2013，，： | 1 |
| 19 | Study on the fluorescence system Be-rutin-SDS-Triton X-100 and the determination of rutin显示文摘 | Jinghe Yang Huabin Zou Nianqin Jie Hongmei Ge Rujun Yang | 1994 | Fresenius’ Journal of Analytical Chemistry (-)1994，，5： | 1 |
| 20 | Numerical simulation and damage analysis of fissure field evolution law in a single coal seam mining显示文摘Based on the different deformation and failure laws of coal and rock materials under tensile or compressive loads,the damage variable was defined to divide three phases from the damage and rupture point of view in order to reveal the fissured field evolution characteristics and spatial distribution of coal and rock in the single coal seam mining with low permeability and rich methane.According to the corresponding damage constitutive equations,the secondary development of the finite element program was completed.The fissures field evolution law of a coal mine with single coal seam mining was calculated and analyzed by this new program and the distribution areas and failure degree of the surrounding coal and rock structures with damage,fissure or rupture are given on the condition of mining.This paper provides a scientific basis for quantitative research and evaluation of the safe simultaneous production of coal and gas. | Feng Gao Xingguang Liu Chaofeng Ge Hongmei Cheng | 2012 | International Journal of Mining Science and Technology2012，22，6： | 1 |
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