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| 1 | Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner显示文摘Cardiovascular disease is still the leading cause of mortality worldwide.Vascular endothelial dysfunction is viewed as the initial step of most cardiovascular diseases.Many studies have indicated that periodontal pathogens,especially Porphyromonas gingivalis,are closely correlated with vascular endothelial homeostasis,but the function of P.gingivalis and the underlying mechanisms are still elusive.To illuminate the effects and elucidate the mechanisms of P.gingivalis on endothelial structural integrity,we developed P.gingivalis infection models in vivo and in vitro.Endothelial cell proliferation,differentiation and apoptosis were detected.Here,we showed that P.gingivalis can impair endothelial integrity by inhibiting cell proliferation and inducing endothelial mesenchymal transformation and apoptosis of endothelial cells,which reduce the cell levels and cause the endothelium to lose its ability to repair itself.A mechanistic analysis showed that TLR antagonist or NF-κB signalling inhibitor can largely rescue the damaged integrity of the endothelium caused by P.gingivalis,suggesting that TLR-NF-κB signalling plays a vital role in vascular endothelial homeostasis destroyed by P.gingivalis.These results suggest a potential intervention method for the prevention and treatment of cardiovascular disease. | Mengru Xie Qingming Tang Shaoling Yu Jiwei Sun Feng Mei Jiajia Zhao Lili Chen | 2020 | International Journal of Oral Science2020，12，3： | 9 |
| 2 | Infrared small target detection using sparse representation显示文摘Sparse representation has recently been proved to be a powerful tool in image processing and object recognition.This paper proposes a novel small target detection algorithm based on this technique.By modelling a small target as a linear combination of certain target samples and then solving a sparse 0-minimization problem,the proposed apporach successfully improves and optimizes the small target representation with innovation.Furthermore,the sparsity concentration index(SCI) is creatively employed to evaluate the coefficients of each block representation and simpfy target identification.In the detection frame,target samples are firstly generated to constitute an over-complete dictionary matrix using Gaussian intensity model(GIM),and then sparse model solvers are applied to finding sparse representation for each sub-image block.Finally,SCI lexicographical evalution of the entire image incorparates with a simple threshold locate target position.The effectiveness and robustness of the proposed algorithm are demonstrated by the exprimental results. | Jiajia Zhao ZhengyuanTang Jie Yang Erqi Liu | 2011 | Journal of Systems Engineering and Electronics2011，22，6： | 9 |
| 3 | Polarization-maintaining few mode fiber composed of a central circular-hole and an elliptical-ring core显示文摘We propose a novel waveguide design of polarization-maintaining few mode fiber(PM-FMF) supporting ≥10non-degenerate modes, utilizing a central circular air hole and a circumjacent elliptical-ring core. The structure endows a new degree of freedom to adjust the birefringence of all the guided modes, including the fundamental polarization mode. Numerical simulations demonstrate that, by optimizing the air hole and elliptical-ring core,a PM-FMF supporting 10 distinctive polarization modes has been achieved, and the effective index difference Δn_(eff) between the adjacent guided modes could be kept larger than 1.32 × 10^(-4) over the whole C +L band. The proposed fiber structure can flexibly tailored to support an even larger number of modes in PM-FMF(14-mode PM-FMF has been demonstrated as an example), which can be readily applicable to a scalable mode division multiplexing system. | JIAJIA ZHAO MING TANG KYUNGHWAN OH ZHENHUA FENG CAN ZHAO RUOLIN LIAO SONGNIAN FU PERRY PING SHUM DEMING LIU | 2017 | Photonics Research2017，5，3： | 9 |
| 4 | ACAT1 regulates the dynamics of free cholesterols in plasma membrane which leads to the APP-a-processing alteration显示文摘 | Ming Zhu Xiaonan Zhao Jia Chen Jiajia Xu Guangjing Hu Dongqing Guo Qin Li Xiaowei Zhang Catherine C.Y. Chang Baoliang Song Ying Xiong Tayuan Chang Boliang Li | 2015 | Acta Biochimica et Biophysica Sinica2015，47，12： | 7 |
| 5 | Gm Ms1 encodes a kinesin-like protein essential for male fertility in soybean(Glycine max L.)显示文摘The application of heterosis is a promising approach for greatly increasing yield in soybean(Glycine max L.). Nuclear male sterility is essential for hybrid seed production and the utilization of heterosis. Here we report the cloning of the gene underlying the soybean male-sterile mutant ms-1,which has been widely used for recurrent selection in soybean breeding programs. We initially delimited the ms1 locus to a 16.15 kb region on chromosome13, based on SLAF_BSA sequencing followed by genotyping of an F_(2) population segregating for the locus. Compared with the same region in fertile plants, the mutant region lacks a sequence of approximately 38.7 kb containing five protein-coding genes, including an ortholog of the kinesin-like protein gene NACK2, named Gm Ms1. The Gm Ms1 knockout plants generated via CRISPR/Casmediated gene editing displayed a complete malesterile phenotype. Metabolic profiling showed that fertile anthers accumulated starch and sucrose normally, whereas sterile anthers had higher anthocyanin levels and lower flavonoid levels and lower antioxidant enzyme activities. These results provide insights into the molecular mechanisms governing male sterility and demonstrate that Gm Ms1 could be used to create male-sterile lines through targeted mutagenesis. These findings pave the way for designing seed production technology and an intelligent male-sterile line system to utilize heterosis in soybean. | Muhammad Nadeem Andong Chen Huilong Hong Dongdong Li Jiajia Li Duo Zhao Wei Wang Xiaobo Wang Lijuan Qiu | 2021 | Journal of Integrative Plant Biology2021，63，6： | 6 |
| 6 | The optional long 5'-untranslated region of human ACAT1 mRNAs impairs the production of ACAT1 protein by promoting its mRNA decay显示文摘我们以前报导了人的 ACAT1 mRNAs 用 AUG13971399 开始 codon 生产 50 kDa 蛋白质,并且另外一个未成年者用在上游的在里面框架 GGC12741276 开始 codon 的 56 kDa isoform。GGC12741276 codon 在可选的长 5-untranslated 区域被定位(5-UTR, nt 11396 ) mRNAs。相应于这 5-UTR 的 DNA 序列位于二个不同染色体, 7 和 1。在当前的工作,我们报导可选的长 5-UTR 显著地损害从 AUG13971399 codon 开始的人的 ACAT1 蛋白质的生产,主要由支持它的 mRNA 腐烂。西方的污点分析显示可选的长 5-UTR potently 损害了从 AUG13971399 codon 开始的不同蛋白质的生产,意味着这损害效果没被 3-UTR 或 ACAT1 mRNA 的编码顺序影响。反向的抄写量的聚合酶链反应的结果证明这 5-UTR 戏剧性地减少了它的连接 mRNAs 的内容。到 mRNA 比率的蛋白质的分析证明这 5-UTR 主要减少了它的 mRNA 稳定性而非改变它的翻译效率。我们下次执行了 plasmid transfection 实验并且使用了放线菌素 D 禁止抄写。结果证明这 5-UTR 支持了它的 mRNA 腐烂。用在 vitro 准备的 RNA 的另外的 transfection 和 nucleofection 实验说明了那,在细胞质和房间的原子核,没有连接,可选的长 5-UTR-linked mRNAs 比那些快腐烂了。总的来说,我们的学习在抄写以后的水平把新卓见带到人的 ACAT1 基因表示的规定。 | Xiaonan Zhao Jia Chen Lei Lei Guangjing Hu Ying Xiong Jiajia Xu Qin Li Xinying Yang Catherine C.Y. Chang Baoliang Song Tayuan Chang Boliang Li | 2009 | Acta Biochimica et Biophysica Sinica2009，41，1： | 6 |
| 7 | Comparative genomic and transcriptomic analyses uncover the molecular basis of high nitrogen-use efficiency in the wheat cultivar Kenong 9204显示文摘Studying the regulatory mechanisms that drive nitrogen-use efficiency(NUE)in crops is important for sustainable agriculture and environmental protection.In this study,we generated a high-quality genome assembly for the high-NUE wheat cultivar Kenong 9204 and systematically analyzed genes related to nitrogen uptake and metabolism.By comparative analyses,we found that the high-affinity nitrate transporter gene family had expanded in Triticeae.Further studies showed that subsequent functional differentiation endowed the expanded family members with saline inducibility,providing a genetic basis for improving the adaptability of wheat to nitrogen deficiency in various habitats.To explore the genetic and molecular mechanisms of high NUE,we compared genomic and transcriptomic data from the high-NUE cultivar Kenong 9204(KN9204)and the low-NUE cultivar Jing 411 and quantified their nitrogen accumulation under high-and low-nitrogen conditions.Compared with Jing 411,KN9204 absorbed significantly more nitrogen at the reproductive stage after shooting and accumulated it in the shoots and seeds.Transcriptome data analysis revealed that nitrogen deficiency clearly suppressed the expression of genes related to cell division in the young spike of Jing 411,whereas this suppression of gene expression was much lower in KN9204.In addition,KN9204 maintained relatively high expression of NPF genes for a longer time than Jing 411 during seed maturity.Physiological and transcriptome data revealed that KN9204 was more tolerant of nitrogen deficiency than Jing 411,especially at the reproductive stage.The high NUE of KN9204 is an integrated effect controlled at different levels.Taken together,our data provide new insights into the molecular mechanisms of NUE and important gene resources for improving wheat cultivars with a higher NUE trait. | Xiaoli Shi Fa Cui Xinyin Han Yilin He Long Zhao Na Zhang Hao Zhang Haidong Zhu Zhexin Liu Bin Ma Shusong Zheng Wei Zhang Jiajia Liu Xiaoli Fan Yaoqi Si Shuiquan Tian Jianqing Niu Huilan Wu Xuemei Liu Zhuo Chen Deyuan Meng Xiaoyan Wang Liqiang Song Lijing Sun Jie Han Hui Zhao Jun Ji Zhiguo Wang Xiaoyu He Ruilin Li Xuebin Chi Chengzhi Liang Beifang Niu Jun Xiao Junming Li Hong-Qing Ling | 2022 | Molecular Plant2022，15，9： | 6 |
| 8 | Advances in Medical Applications of Additive Manufacturing显示文摘In the past few decades,additive manufacturing(AM)has been developed and applied as a cost-effective and versatile technique for the fabrication of geometrically complex objects in the medical industry.In this review,we discuss current advances of AM in medical applications for the generation of pharmaceuticals,medical implants,and medical devices.Oral and transdermal drugs can be fabricated by a variety of AM technologies.Different types of hard and soft clinical implants have also been realized by AM,with the goal of producing tissue-engineered constructs.In addition,medical devices used for diagnostics and treatment of various pathological conditions have been developed.The growing body of research on AM reveals its great potential in medical applications.The goal of this review is to highlight the usefulness and elucidate the current limitations of AM applications in the medical field. | Chunxu Li Dario Pisignano Yu Zhao Jiajia Xue | 2020 | Engineering2020，6，11： | 4 |
| 9 | Mutant p53 increases exosome-mediated transfer of mi R-21-3p and mi R-769-3p to promote pulmonary metastasis显示文摘Objective: Tumor metastasis is a complex, multistep process that depends on tumor cells and their communication with the tumor microenvironment. A p53 gain-of-function mutant has been shown to enhance the tumorigenesis, invasion, and metastasis abilities of tumor cells. This study aimed to investigate the roles of p53 R273 H mutation in the tumor microenvironment.Methods: The in vitro and in vivo effects of the p53 R273 H mutant on the invasion and metastasis of HCT116 cells were investigated. Exosomes from wild-type and HCT116-TP53(R273 H) cells were cocultured with mouse embryonic fibroblasts(MEFs). The roles of differentially expressed exosomal micro RNAs identified by microarray analysis were investigated. The functions of the p53 R273 H mutant in tumor cells were also investigated via gene expression microarray and quantitative polymerase chain reaction(q PCR) analyses.Results: Introducing p53 R273 H mutant into HCT116 cells significantly potentiated pulmonary metastasis in vivo. In the presence of exosomes derived from HCT116-TP53(R273 H) cells, the exosomes were taken up by MEFs and became activated. Microarray analysis showed that the p53 R273 H mutation increased the exosomal levels of mi R-21-3 p and mi R-769-3 p. Intriguingly, in clinical samples, mi R-21-3 p and mi R-769-3 p levels were significantly higher in patients with a p53 mutation than in those without this mutation. Furthermore, both mi R-21-3 p and mi R-769-3 p activated fibroblasts and exerted a synergistic effect via their target genes on the transforming growth factor-β(TGF-β)/Smad signaling pathway. The activated fibroblasts excreted cytokine TGF-β and may have reciprocally induced cancer cells to undergo epithelial-mesenchymal transition(EMT). Indeed, HCT116-TP53(R273 H) cells showed increased expression of ZEB1 and SNAI2 and decreased transcription of several cell adhesion molecules.Conclusions: The mutant p53-exosomal mi R-21-3 p/mi R-769-3 p-fibroblast-cytokine circuit appears to be responsible for communication between tumor and stromal cells, with exosomal mi RNAs acting as a bridge. mi R-21-3 p and mi R-769-3 p are potential predictive markers of pulmonary metastasis and candidate targets for therapeutic interventions. | Qiang Ju Lina Zhao Jiajia Gao Lanping Zhou Yang Xu Yulin Sun Xiaohang Zhao | 2019 | Chinese Journal of Cancer Research2019，31，3： | 4 |
| 10 | Identification of a novel seed size associated locus SW9-1 in soybean显示文摘Seed size is one of the vital traits determining seed appearance, quality, and yield. Untangling the genetic mechanisms regulating soybean 100-seed weight (100-SW), seed length and seed width across environments may provide a theoretical basis for improving seed yield. However, there are few reports related to QTL mapping of 100-SW across multiple ecological regions. In this study, 21 loci associated with seed size traits were identified using a genome-wide association of 5361 single nucleotide polymorphisms (SNPs) across three ecoregions in China, which could explain 8.12%–14.25% of the phenotypic variance respectively. A new locus, named as SW9-1 on chromosome 9 that explained 10.05%–10.93% of the seed weight variance was found significantly related to seed size traits, and was not previously reported. The selection effect analysis showed that SW9-1 locus has a relatively high phenotypic effect (13.67) on 100-SW, with a greater contribution by the accessions with bigger seeds (3.69) than the accessions with small seeds (1.66). Increases in seed weight were accompanied by increases in the frequency of SW9-1T allele, with >90% of the bred varieties with a 100-SW >30 g carrying SW9-1T. Analysis of SW9-1 allelic variation in additional soybean accessions showed that SW9-1T allele accounting for 13.83% of the wild accessions, while in 46.55% and 51.57% of the landraces and bred accessions, respectively, this results indicating that the SW9-1 locus has been subjected to artificial selection during the early stages of soybean breeding, especially the utilization of SW9-1T in edamame for big seed. These results suggest that SW9-1 is a novel and reliable locus associated with seed size traits, and might have an important implication for increasing soybean seed weight in molecular design breeding. Cloning this locus in future may provide new insights into the genetic mechanisms underlying soybean seed size traits. | Jiajia Li Jinghui Zhao Yinghui Li Yali Gao Sunan Hua Muhammad Nadeem Genlou Sun Wenming Zhang Jinfeng Hou Xiaobo Wang Lijuan Qiu | 2019 | The Crop Journal2019，7，4： | 4 |
| 11 | Formation and evolution of the tertiary carbonate reefs in the Madura Strait Basin of Indonesia显示文摘Analysis of 2 D seismic data over 4 500 km in length from the Madura Strait Basin in the East Java Sea reveals seismic re?ection characteristics of reefs and associated sedimentary bodies, including asymmetrical or symmetrical dome re?ections, slope progradational re?ections, chaotic re?ections and discontinuous strong re?ections inside the reef, which onlap the ?ank of the reef. It is concluded that the developmental paleo-environment of most reefs is mainly conducive to shallow marine carbonate platform facies and platform margin facies, based on well core data, variations in seismic facies and strata thickness.The formation and evolution of all reefs are primarily in?uenced by the tectonic framework of the Madura Strait Basin. Platform margin reefs are principally controlled by two types of structures: one is a series of E-W trending Paleogene normal faults, and the other is an E-W trending Neogene inversion structures. In addition, wave actions, tidal currents and other ocean currents play an accelerated role in sorting, rounding and redeposition for the accumulation and evolution of reefs. Tertiary reefs in the MSB can be divided into four types: 1) an open platform coral reef of Late Oligocene to Early Miocene, 2) a platform margin coral reef controlled by normal faults in Late Oligocene to Early Miocene, 3) a platform margin Globigerina moundreef controlled by a 'hidden' inversion structure in Early Pliocene, and 4) a platform margin Globigerina mound-reef controlled by thrust faults in the early Pliocene. Patterns of the formation and evolution of reefs are also suggested. | RAN Weimin LUAN Xiwu LU Yintao LIU Hong YANG Jiajia ZHAO Yang HE Wenchang YAN Zhonghui | 2019 | Journal of Oceanology and Limnology2019，37，1： | 3 |
| 12 | Green Fabrication of Multifunctional Three‑Dimensional Superabsorbent Nonwovens with Thermo‑Bonding Fibers显示文摘Disposable hygiene products have evolved into the important parts for millions of people around the world,enhancing the convenience of daily lives.However,development of the disposable hygiene products is restricted by unsustainable production technology,complicated operation process,and poor liquid absorption performance of the absorbent core.Herein,integrated and three-dimensional(3D)multifunctional superabsorbent nonwovens with liquid-triggered fragrance release was prepared via green,fast and scalable multi efect hot-air anchoring method which physically crosslinking the joint thermobonding fbers and anchoring fragrance microcapsules/super absorbent polymer(SAP)onto adjacent thermo-bonding fbers simultaneously.The resulting composite nonwovens could three-dimensionally absorb water 33.14 times of its own weight without gel blockage between SAP,and correspondingly release increased intensity fragrance along with enhancing amount of water absorption.Absorption rate t1 and t2 is 83.62%and 50.62%higher than the commercial specimen respectively,and the air permeability is increased by 226.88%compared with the commercial specimen.The superabsorbent nonwovens with controllable fragrance release and odorant synergistic has the potential to be practically applied to functional textiles felds because of the excellent liquid absorption and controlled fragrance release performance,and is easy to be produced on a sustainable,pollution-free and large-scale industrial production. | Jiajia Ma Nan Zhang Ying Cheng Xingran Kou Yunwei Niu Xiangyu Jin Qinfei Ke Yi Zhao | 2022 | Advanced Fiber Materials2022，4，2： | 3 |
| 13 | Semi-enclosed experimental system for coal spontaneous combustion for determining regional distribution of high-temperature zone of coal fire显示文摘Temperature variation and gas generation at diferent depths and positions in the coal combustion process were studied to determine the propagation and evolution of high temperature regions in the process of coal spontaneous combustion.This study selected coal samples from Mengcun,Shaanxi Province,People’s Republic of China,and developed a semi-enclosed experimental system(furnace)for simulating coal combustion.The thermal mass loss of coal samples under various heating rates(5,10,and 15℃/min)was analyzed through thermogravimetric analysis,and the dynamic characteristics of the coal samples were analyzed;the reliability of the semi-enclosed experimental system was verifed through the equal proportional method of fuzzy response.The results reveal that the high-temperature zone is distributed nonlinearly from the middle to the front end of the furnace,and the temperatures of points in this zone decreased gradually as the layer depth increased.The apparent activation energy of the coal samples during combustion frst increased and then decreased as the conversion degree increased.Furthermore,the proportion of mass loss and the mass loss rate in the coal samples observed in the thermogravimetric experiment is consistent with that observed in the frst and second stages of the experiment conducted using the semi-enclosed system.The research fndings can provide a theoretical basis for the prevention and control of hightemperature zones in coal combustion. | Jingyu Zhao Hanqi Ming Tao Guo Yuxuan Zhang Jun Deng Jiajia Song Qiang Zeng Chi‑Min Shu | 2022 | International Journal of Coal Science & Technology2022，9，5： | 3 |
| 14 | Non-equidistance DGM(1,1) Model Based on the Concave Sequence and Its Application to Predict the China’s Per Capita Natural Gas Consumption显示文摘Although the grey forecasting model has been successfully adopted in various fields and demonstrated promising results, the literatures show its performance could be further improved, such as for the DGM(1,1) model, based on a concave sequence, the modeling error will be larger. In this paper,firstly the definition of sequence convexity is given out, and it is proved that the output sequence of DGM(1,1) model is a convex sequence. Next, the residual change law of DGM(1,1) model based on the concave sequence is discussed, and the non-equidistance DGM(1,1) model is proposed. Finally, by introducing the symmetry transformation, a concave sequence is transformed into a convex sequence, called the symmetric sequence of the concave sequence, and then construct the non-equidistance DGM(1,1)model based on the convex sequence. The example results show that the novel method is more accurate than the direct modeling for a concave sequence. | Xinhai KONG Yong ZHAO Jiajia CHEN | 2018 | Journal of Systems Science and Information2018，9，4： | 2 |
| 15 | Low intensity near-infrared light promotes bone regeneration via circadian clock protein cryptochrome 1显示文摘Bone regeneration remains a great clinical challenge. Low intensity near-infrared(NIR) light showed strong potential to promote tissue regeneration, offering a promising strategy for bone defect regeneration. However, the effect and underlying mechanism of NIR on bone regeneration remain unclear. We demonstrated that bone regeneration in the rat skull defect model was significantly accelerated with low-intensity NIR stimulation. In vitro studies showed that NIR stimulation could promote the osteoblast differentiation in bone mesenchymal stem cells(BMSCs) and MC3T3-E1 cells, which was associated with increased ubiquitination of the core circadian clock protein Cryptochrome 1(CRY1) in the nucleus. We found that the reduction of CRY1 induced by NIR light activated the bone morphogenetic protein(BMP) signaling pathways, promoting SMAD1/5/9 phosphorylation and increasing the expression levels of Runx2 and Osterix. NIR light treatment may act through sodium voltage-gated channel Scn4a, which may be a potential responder of NIR light to accelerate bone regeneration. Together, these findings suggest that low-intensity NIR light may promote in situ bone regeneration in a CRY1-dependent manner, providing a novel, efficient and non-invasive strategy to promote bone regeneration for clinical bone defects. | Jinfeng Peng Jiajia Zhao Qingming Tang Jinyu Wang Wencheng Song Xiaofeng Lu Xiaofei Huang Guangjin Chen Wenhao Zheng Luoying Zhang Yunyun Han Chunze Yan Qian Wan Lili Chen | 2022 | International Journal of Oral Science2022，14，4： | 2 |
| 16 | Mitochondria targeting drugs for neurodegenerative diseases——Design, mechanism and application显示文摘Neurodegenerative diseases(NDDs) such as Alzheimer’s disease(AD) and Parkinson ’s disease(PD) are a heterogeneous group of disorders characterized by progressive degeneration of neurons.NDDs threaten the lives of millions of people worldwide and regretfully remain incurable.It is well accepted that dysfunction of mitochondria underlies the pathogenesis of NDDs.Dysfunction of mitochondria results in energy depletion,oxidative stress,calcium overloading,caspases activation,which dominates the neuronal death of NDDs.Therefore,mitochondria are the preferred target for intervention of NDDs.So far various mitochondria-targeting drugs have been developed and delightfully some of them demonstrate promising outcome,though there are still some obstacles such as targeting specificity,delivery capacity hindering the drugs development.In present review,we will elaborately address 1) the strategy to design mitochondria targeting drugs,2) the rescue mechanism of respective mitochondria targeting drugs,3) how to evaluate the therapeutic effect.Hopefully this review will provide comprehensive knowledge for understanding how to develop more effective drugs for the treatment of NDDs. | Jiajia Xu Wei Du Yunhe Zhao Kahleong Lim Li Lu Chengwu Zhang Lin Li | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 2 |
| 17 | Corporate Social Capital and Business Model Innovation: The Mediating Role of Organizational Learning显示文摘存在研究证明社团的社会资本不能仅仅使一个公司能获得存取到异构的信息和资源,但是可以也在它的社会网络与股东一起便于行为的标准,通讯模型和相互信任的平台的建立。作为结果,社团的社会资本驾驶组织上的变化并且有潜力增加企业模型革新。这篇论文认出作为把社团的社会资本转变成企业模型革新的调停的机制的组织上的学习。用从 164 个中国公司收集的调查数据,我们测试了在社团的社会资本和企业模型之间的关系革新,以及组织上的学习的调停的效果。我们的调查结果清楚地显示出社团的社会资本怎么通过到生意的努力为革新建模的组织上的学习流动。 | Jing Zhao Ming Wang Limin Zhu Jiajia Ding | 2014 | Frontiers of Business Research in China2014，8，4： | 2 |
| 18 | Cross-task emotion recognition using EEG measures: first step towards practical application显示文摘Electroencephalographic(EEG)-based emotion recognition has received increasing attention in the field of human-computer interaction(HCI)recently,there however remains a number of challenges in building a generalized emotion recognition model,one of which includes the difficulty of an EEG-based emotion classifier trained on a specific task to handle other tasks.Lit-tle attention has been paid to this issue.The current study is to determine the feasibility of coping with this challenge using feature selection.12 healthy volunteers were emotionally elicited when conducting picture induced and videoinduced tasks.Firstly,support vector machine(SVM)classifier was examined under within-task conditions(trained and tested on the same task)and cross-task conditions(trained on one task and tested on another task)for pictureinduced and videoinduced tasks.The within-task classification performed fairly well(classification accuracy:51.6%for picture task and 94.4%for video task).Cross-task classification,however,deteriorated to low levels(around 44%).Trained and tested with the most robust feature subset selected by SVM-recursive feature elimination(RFE),the performance of cross-task classifier was significantly improved to above 68%.These results suggest that cross-task emotion recognition is feasible with proper methods and bring EEG-based emotion recognition models closer to being able to discriminate emotion states for any tasks. | LIU Shuang MENG Jiayuan ZHAO Xin YANG Jiajia HE Feng QI Hongzhi ZHOU Peng HU Yong MING Dong | 2014 | Instrumentation2014，1，3： | 2 |
| 19 | Following Control for a UUV using Temporary Path Generation Guidance显示文摘一个路径追随者控制算法为一无人在水下用暂时的路径产生指导的车辆(UUV ) 在这份报纸被建议。由于车辆的不同起始的状态,例如位置和取向,在水平飞机的路径追随者控制可以产出差的表演。为了处理否定效果,由起始的状态导致了,暂时的路径代基于在原来的参考书路径和车辆之间的关系被介绍起始的状态。与在车辆和参考书路径之间的不同相对位置,从直线,以及里面并且在一个圆外面包括,指导车辆到参考书路径的相关暂时的路径能在实时被产生。车辆被指导驾驶暂时的路径直到它在参考书路径到达了正切点,在控制器用输入产量反馈 linearization 方法被设计的地方。模拟结果证明建议算法在上面提及的三种不同状况下面是有效的。 | Zheping Yan Dongnan Chi Jiajia Zhou Yufei Zhao | 2012 | Journal of Marine Science and Application2012，11，2： | 2 |
| 20 | Comparative population genomics dissects the genetic basis of seven domestication traits in jujube显示文摘Jujube(Ziziphus jujuba Mill.)is an important perennial fruit tree with a range of interesting horticultural traits.It was domesticated from wild jujube(Ziziphus acidojujuba),but the genomic variation dynamics and genetic changes underlying its horticultural traits during domestication are poorly understood.Here,we report a comprehensive genome variation map based on the resequencing of 350 accessions,including wild,semi-wild and cultivated jujube plants,at a>15×depth.Using the combination of a genome-wide association study(GWAS)and selective sweep analysis,we identified several candidate genes potentially involved in regulating seven domestication traits in jujube.For fruit shape and kernel shape,we integrated the GWAS approach with transcriptome profiling data,expression analysis and the transgenic validation of a candidate gene to identify a causal gene,ZjFS3,which encodes an ethyleneresponsive transcription factor.Similarly,we identified a candidate gene for bearing-shoot length and the number of leaves per bearing shoot and two candidate genes for the seed-setting rate using GWAS.In the selective sweep analysis,we also discovered several putative genes for the presence of prickles on bearing shoots and the postharvest shelf life of fleshy fruits.This study outlines the genetic basis of jujube domestication and evolution and provides a rich genomic resource for mining other horticulturally important genes in jujube. | Mingxin Guo Zhongren Zhang Yanwei Cheng Sunan Li Peiyin Shao Qiang Yu Junjie Wang Gan Xu Xiaotian Zhang Jiajia Liu Linlin Hou Hanxiao Liu Xusheng Zhao | 2020 | Horticulture Research2020，7，1： | 2 |
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