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| 1 | Prevalence of Autism Spectrum Disorder in China:A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years显示文摘This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling.The Modified Chinese Autism Spectrum Rating Scale was used for the screening process.Of the target population of 142,086 children,88.5%(n=125,806) participated in the study.A total of 363 children were confirmed as having ASD.The observed ASD prevalence rate was 0.29%(95% CI:0.26%-0.32%) for the overall population.After adjustment for response rates,the estimated number of ASD cases was867 in the target population sample,thereby achieving an estimated prevalence of 0.70%(95% CI:0.64%-0.74%).The prevalence was significantly higher in boys than in girls(0.95%;95% CI:0.87%-1.02% versus 0.30%;95%CI:0.26%-0.34%;P <0.001).Of the 363 confirmed ASD cases,43.3% were newly diagnosed,and most of those(90.4%) were attending regular schools,and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity.Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children. | Hao Zhou Xiu Xu Weili Yan Xiaobing Zou Lijie Wu Xuerong Luo Tingyu Li Yi Huang Hongyan Guan Xiang Chen Meng Mao Kun Xia Lan Zhang Erzhen Li Xiaoling Ge Lili Zhang Chunpei Li Xudong Zhang Yuanfeng Zhou Ding Ding Andy Shih Eric Fombonne Yi Zheng Jisheng Han Zhongsheng Sun Yong-hui Jiang Yi Wang LATENT-NHC Study Team | 2020 | Neuroscience Bulletin2020，36，9： | 158 |
| 2 | Enhanced base editing by co-expression of free uracil DNA glycosylase inhibitor显示文摘 | Lijie Wang Wei Xue Lei Yan Xiaosa Li Jia Wei Miaomiao Chen Jing Wu Bei Yang Li Yang Jia Chen | 2017 | Cell Research2017，27，10： | 26 |
| 3 | Chitosan conduits combined with nerve growth factor microspheres repair facial nerve defects显示文摘Microspheres containing nerve growth factor for sustained release were prepared by a compound method,and implanted into chitosan conduits to repair 10-mm defects on the right buccal branches of the facial nerve in rabbits.In addition,chitosan conduits combined with nerve growth factor or normal saline,as well as autologous nerve,were used as controls.At 90 days post-surgery,the muscular atrophy on the right upper lip was more evident in the nerve growth factor and normal saline groups than in the nerve growth factor-microspheres and autologous nerve groups.Electrophysiological analysis revealed that the nerve conduction velocity and amplitude were significantly higher in the nerve growth factor-microspheres and autologous nerve groups than in the nerve growth factor and normal saline groups.Moreover,histological observation illustrated that the diameter,number,alignment and myelin sheath thickness of myelinated nerves derived from rabbits were higher in the nerve growth factor-microspheres and autologous nerve groups than in the nerve growth factor and normal saline groups.These findings indicate that chitosan nerve conduits combined with microspheres for sustained release of nerve growth factor can significantly improve facial nerve defect repair in rabbits. | Huawei Liu Weisheng Wen Min Hu Wenting Bi Lijie Chen Sanxia Liu Peng Chen Xinying Tan | 2013 | Neural Regeneration Research2013，8，33： | 22 |
| 4 | Walnut-inspired microsized porous silicon/graphene core-shell composites for high-performance lithium-ion battery anodes显示文摘 | Wei Zhai Qing Ai Lina Chen Shiyuan Wei Deping Li Lin Zhang Pengchao Si Jinkui Feng Lijie Ci | 2017 | Nano Research2017，10，12： | 12 |
| 5 | Co-inhibition of methanogens for methane mitigation in biodegradable wastes显示文摘The inhibition effects and mechanisms of chlorinated methane and acetylene on methanogenesis in the anaerobic digestion process of the biodegradable wastes were investigated.It was found that both chloroform and acetylene could effectively inhibit methanogens while the biodegradability of the wastes was not affected.Acetylene inhibited the activity of methanogens,while chloroform inhibited metabolic process of methanogenesis.A central composite design(CCD) and response surface regression analysis(RSREG) were employed to determine the optimum conditions and interaction effects of chloroform and acetylene in terms of inhibition effciency,production of volatile fatty acids(VAF) and molar ratio of propionic acid to acetic acid.Chloroform had significant effect on enhancing the production of VFA(F = 121.3;p < 0.01),and acetylene promoted the inhibition effciency(F = 99.15;p < 0.05) more effectively than chloroform(F = 9.72;p > 0.05).In addition,a maximum molar ratio of propionic acid to acetic acid of 1.208 was estimated under the optimum conditions of chloroform concentration of 9.05 mg/kg and acetylene concentration of 3.6×10-3(V/V).Hence,methanogens in the wastes can be inhibited while the stabilization process of the biodegradable wastes can still work well,as propionic acid generated during the inhibition process could hardly be utilized by methanogens. | ZHAO Tiantao ZHANG Lijie CHEN Haoquan ZHAO Youcai | 2009 | Journal of Environmental Sciences2009，21，6： | 12 |
| 6 | Whole-Genome Resequencing of a Worldwide Collection of Rapeseed Accessions Reveals the Genetic Basis of Ecotype Divergence显示文摘Rapeseed (Brassica napus),an important oilseed crop,has adapted to diverse climate zones and latitudes by forming three main ecotype groups,namely winter,semiwinter,and spring types. However,genetic variations underlying the divergence of these ecotypes are largely unknown. Here,we report the global pattern of genetic polymorphisms in rapeseed determined by resequencing a worldwide collection of 991 germplasm accessions.A total of 5.56 and 5.53 million singlenucleotide polymorphisms (SNPs)as Well as 1.86 and 1.92 million InDels were identified by mapping reads to the reference genomes of 'Darmor-bzh'and 'Tapidor,'respectively.We generated a map of allelic drift paths that shows splits and mixtures of the main populations,and revealed an asymmetric evolution of the two subgenomes of B.napus by calculating the genetic diversity and linkage disequilibrium parameters.Selective-sweep analysis revealed genetic changes in genes orthologous to those regulating various aspects of plant development and response to stresses.A genome-wide association study identified SNPs in the promoter regions of FLOWERING LOCUS T and FLOWERING LOCUS C orthologs that corresponded to the different rapeseed ecotype groups. Our study provides important insights into the genomic footprints of rapeseed evolution and flowering-time divergence among three ecotype groups,and will facilitate screening of molecular markers for accelerating rapeseed breeding. | Dezhi Wu Zhe Liang Tao Yan Ying Xu Lijie Xuan Juan Tang Gang Zhou Ulrike Lohwasser Shuijin Hua Haoyi Wang Xiaoyang Chen Qian Wang Le Zhu Antony Maodzeka Nazim Hussain Zhilan Li Xuming Li Imran Haider Shamsi Ghulam Jilani Linde Wu Hongkun Zheng Guoping Zhang Boulos Chalhoub Lisha Shen Hao Yu Lixi Jiang | 2019 | Molecular Plant2019，12，1： | 10 |
| 7 | Microstructure and corrosion resistance of ultrasonic micro-arc oxidation biocoatings on magnesium alloy显示文摘The ultrasonic micro-arc oxidation(UMAO)was used to fabricate ceramic coatings on magnesium alloy.UMAO coatings were produced at 60 W input ultrasonic.The effects of the ultrasound on the microstructure,phase composition,elemental distribution and corrosion resistance of the coatings were extensively investigated by scanning electron microscopy(SEM),X-ray diffraction(XRD),energy-dispersive X-ray spectrometry(EDX)and electrochemical workstation.The results showed that ultrasound improved the homogeneous distribution of micro-porous structure.The coatings were mainly composed of MgO ceramic and small amount of calcium and phosphorus with porous structure.The Ca/P ratio of the coatings increased when 60 W ultrasonic was used.The corrosion potential in simulated body fluid(SBF)changed from��1.583 V of bare magnesium alloy to -0.353 V of magnesium alloy coated under 60 W ultrasonic.The corrosion resistance of UMAO coatings was better than that of MAO coatings. | Lijie QU Muqin LI Miao LIU Erlin ZHANG Chen MA | 2013 | Journal of Advanced Ceramics2013，2，3： | 9 |
| 8 | Highly efficient and precise base editing in discarded human tripronuclear embryos显示文摘 | Guanglei Li Yajing Liu Yanting Zeng Jianan Li Lijie Wang Guang Yang Dunjin Chen Xiaoyun Shang Jia Chen Xingxu Huang Jianqiao Liu | 2017 | Protein & Cell2017，8，10： | 8 |
| 9 | National 2000' GPS control network of China显示文摘有超过 2500 个车站的一个精确地统一的国家 GPS 网络,说出“国家 2000' GPS 控制 Netweork ”,签署了时代 2000.0,被集成存在建立了中国的六个全国性的 GPS 网络与不同目的由不同部门建立了。这篇论文论述令人激动的 GPS 网络的特征,在 GPS 网络,包括的功能的模型,随机的模型以及调整的综合调整总结策略原则修正。由根据存在 GPS 网络并且在 IGS 车站的支持下面的特征修改调整策略,综合国家 GPS 网络的精确性极大地被改进。在潜水艇网络之中的资料差别消失,系统的错误影响被削弱,并且估计的坐标和他们的变化上的孤立点的效果被控制。为水平部件的平均标准差当时更小,这被显示出 1.0 厘米,垂直部件比 2.0 厘米小,并且三维(3-D ) geocenter 坐标的位置比 3.0 厘米小。为 3-D 位置的外面的检查精确性比 1.0 厘米平均好。 | Yang Yuanxi Tang Yingzhe Chen Chuanlu Wang Min Zhang Peng Wang Xiaorui Song Lijie Zhang Zusheng | 2007 | Progress in Natural Science:Materials International2007，17，8： | 7 |
| 10 | A load simulation method of piezoelectric actuator in FEM for smart structures显示文摘More and more piezoelectric materials and structures have been used for structure control in aviation and aerospace industry. More efficient and convenient computation method for large complex structure with piezoelectric actuation devices is required. A load simulation method of piezoelectric actuation is presented in this paper. By this method, the freedom degree of finite element simulation is significantly reduced, the difficulty in defining in-plane voltage for multi-layers piezoelectric composite is overcome and the transfer computation between material main direction and the element main direction is simplified. The concept of simulation load is comprehensible and suitable for engineers of structure strength in shape and vibration control, thereby is valuable for promoting the application of piezoelectric material and structures in practical aviation and aerospace fields. | LI Min CHEN WeiMin WANG MingChun JIA LiJie | 2009 | Science China(Technological Sciences)2009，52，9： | 7 |
| 11 | Co-pyrolysis characteristics of typical components of waste plastics in a falling film pyrolysis reactor显示文摘Waste plastics mainly come from MSW and usually exist in the form of mixed plastics. During the co-pyrolysis process of mixed plastics, various plastic components have different physicochemical properties and reaction mechanisms. Considering the high viscosity and low thermal conductivity of molten plastics, a falling film pyrolysis reactor was selected to explore the rapid co-pyrolysis process of typical plastic components(PP, PE and PS).The oil and gas yields and the compositions of pyrolysis products of the three components under different ratios at pyrolysis temperatures were analyzed to explore the co-pyrolysis characteristics of PP, PE, and PS. The study is of great significance to the recycling of waste plastics. | Zechen Jin Lijie Yin Dezhen Chen Yuanjie Jia Jun Yuan Yuyan Hu | 2018 | Chinese Journal of Chemical Engineering2018，26，10： | 5 |
| 12 | Highly luminescent and stable lead-free cesium copper halide perovskite powders for UV-pumped phosphor-converted light-emitting diodes显示文摘Lead halide perovskites have drawn extensive attention over recent decades owing to their outstanding photo-electric performances.However,their toxicity and instability are big issues that need to be solved for further commercialization.Herein,we adopt a facile dry ball milling method to synthesize lead-free Cs3Cu2X5(X=I,CI)perovskites with photoluminescence(PL)quantum yield up to 60%.The optical features including broad emission spectrum,large Stokes shift,and long PL lifetime can be attributed to self-trapped exciton recombination.The as-synthesized blue emissive Cs3Cu2I5 and green emissive Cs3Cu2Cl5 lead-free perovskite powders have good thermal stability and photostability.Furthermore,UV-pumped phosphor-converted light-emitting diodes were obtained by using Cs3Cu2I5 and Cs3Cu2Cl5 as phosphors. | LINGLING XIE BINGKUN CHEN FA ZHANG ZHENG ZHAO XINXIN WANG LIJIE SHI YUE LIU LINGLING HUANG RUIBIN LIU BINGSUO ZOU YONGTIAN WANG | 2020 | Photonics Research2020，8，6： | 5 |
| 13 | Monitoring Soil Salt Content Using HJ-1A Hyperspectral Data: A Case Study of Coastal Areas in Rudong County, Eastern China显示文摘Hyperspectral data are an important source for monitoring soil salt content on a large scale. However, in previous studies, barriers such as interference due to the presence of vegetation restricted the precision of mapping soil salt content. This study tested a new method for predicting soil salt content with improved precision by using Chinese hyperspectral data, Huan Jing-Hyper Spectral Imager(HJ-HSI), in the coastal area of Rudong County, Eastern China. The vegetation-covered area and coastal bare flat area were distinguished by using the normalized differential vegetation index at the band length of 705 nm(NDVI705). The soil salt content of each area was predicted by various algorithms. A Normal Soil Salt Content Response Index(NSSRI) was constructed from continuum-removed reflectance(CR-reflectance) at wavelengths of 908.95 nm and 687.41 nm to predict the soil salt content in the coastal bare flat area(NDVI705 < 0.2). The soil adjusted salinity index(SAVI) was applied to predict the soil salt content in the vegetation-covered area(NDVI705 ≥ 0.2). The results demonstrate that 1) the new method significantly improves the accuracy of soil salt content mapping(R2 = 0.6396, RMSE = 0.3591), and 2) HJ-HSI data can be used to map soil salt content precisely and are suitable for monitoring soil salt content on a large scale. | LI Jianguo PU Lijie ZHU Ming DAI Xiaoqing XU Yan CHEN Xinjian ZHANG Lifang ZHANG Runsen | 2015 | Chinese Geographical Science2015，25，2： | 4 |
| 14 | The Impact of COVID-19 Epidemic on Tuberculosis Reports Among Students — Guizhou Province, China, 2020显示文摘Summary What is already known about this topic?In 2020,the implementation of non-medical interventions during the coronavirus disease 2019(COVID-19)epidemic has created a negative impact on tuberculosis(TB)control.It is unclear if the prevalence of TB among students in Guizhou Province was also affected.What is added by this report?Among TB cases,the proportion of student TB patients was 19.91%in the back-to-school period in 2020,which was higher than the 13.37%registered in 2017–2019,but this decreased in the COVID-19 pandemic period.The time interval between symptom onset and care-seeking of the student TB patients was the shortest in the back-to-school and physical checkup periods.What are the implications for public health practice?TB active screening was effective for timely detection and diagnosis of TB among students,which could prevent TB outbreaks in schools. | Yuying He Tao Li Lijie Zhang Renzhong Li Zaiping Chen Yunzhou Ruan Wei Su Jinlan Li | 2022 | China CDC weekly2022，4，11： | 3 |
| 15 | Preparation, Crystal Structure and Properties of a New Crystal Form of Diammonium 5,5'-bistetrazole-1,1'-diolate显示文摘 | Xiaojun Wang Shaohua Jin Chunyuan Zhang Lijie Li Shusen Chen Qinghai Shu | 2015 | Chinese Journal of Chemistry2015，33，11： | 3 |
| 16 | Key Recovery Against 3DES in CPU Smart Card Based on Improved Correlation Power Analysis显示文摘The security of CPU smart cards,which are widely used throughout China,is currently being threatened by side-channel analysis.Typical countermeasures to side-channel analysis involve adding noise and filtering the power consumption signal.In this paper,we integrate appropriate preprocessing methods with an improved attack strategy to generate a key recovery solution to the shortcomings of these countermeasures.Our proposed attack strategy improves the attack result by combining information leaked from two adjacent clock cycles.Using our laboratory-based power analysis system,we verified the proposed key recovery solution by performing a successful correlation power analysis on a Triple Data Encryption Standard(3DES)hardware module in a real-life 32-bit CPU smart card.All 112 key bits of the 3DES were recovered with about 80 000 power traces. | Yanting Ren Liji Wu Hexin Li Xiangyu Li Xiangmin Zhang An Wang Hongyi Chen | 2016 | Tsinghua Science and Technology2016，21，2： | 3 |
| 17 | Non-dormant Axillary Bud 1 regulates axillary bud outgrowth in sorghum显示文摘Tillering contributes to grain yield and plant architecture and therefore is an agronomically important trait in sorghum(Sorghum bicolor).Here,we identified and functionally characterized a mutant of the Nondormant Axillary Bud 1(NAB1)gene from an ethyl methanesulfonate-mutagenized sorghum population.The nab1 mutants have increased tillering and reduced plant height.Map-based cloning revealed that NAB1encodes a carotenoid-cleavage dioxygenase 7(CCD7)orthologous to rice(Oryza sativa)HIGH-TILLERING DWARF1/DWARF17 and Arabidopsis thaliana MORE AXILLARY BRANCHING 3.NAB1 is primarily expressed in axillary nodes and tiller bases and NAB1 localizes to chloroplasts.The nab1 mutation causes outgrowth of basal axillary buds;removing these non-dormant basal axillary buds restored the wild-type phenotype.The tillering of nab1 plants was completely suppressed by exogenous application of the synthetic strigolactone analog GR24.Moreover,the nab1plants had no detectable strigolactones and displayed stronger polar auxin transport than wild-type plants.Finally,RNA-seq showed that the expression of genes involved in multiple processes,including auxin-related genes,was significantly altered in nab1.These results suggest that NAB1 functions in strigolactone biosynthesis and the regulation of shoot branching via an interaction with auxin transport. | Jun Chen Limin Zhang Mengjiao Zhu Lijie Han Ya Lv Yishan Liu Pan Li Haichun Jing Hongwei Cai | 2018 | Journal of Integrative Plant Biology2018，60，10： | 3 |
| 18 | Generation of purple-violet chrysanthemums via anthocyanin B-ring hydroxylation and glucosylation introduced from Osteospermum hybrid F3'5'H and Clitoria ternatea A3'5'GT显示文摘Chrysanthemums possess no metabolic pathway to synthesize delphinidin because of the lack of endogenous F3'5'H gene encoding the key enzyme in its biosynthetic pathway;therefore,there are no blue or blue-purple chrysanthemums occurring naturally.Currently,the introduction of exogenous F3'5'H into chrysanthemums is an efficient method for breeding bluish chrysanthemums.In this study,we explored the effects of the introduction of mutant CmF3'H(generated via site-directed mutagenesis,T485S,CmF3'Hm)and exogenous Osteospermum hybrid F3'5'H(OhF3'5'H)genes combined with Clitoria ternatea A3'5'GT(CtA3'5'GT)on delphinidin synthesis in chrysanthemum.Among the F3'5'H transgenic lines,those overexpressing endogenous CmF3'Hm could not generate blue flower color,although red color was changed to light pink due to CtA3'5'GT function.Meanwhile,OhF3'5'H introduction promoted the accumulation of delphinidin and its derivatives in chrysanthemum,changing the flower color from red-purple to purple-violet.These results indicate the applicability of exogenous OhF3'5'H and CtA3'5'GT transformation for promoting delphinidin synthesis during the molecular breeding of violet/blue chrysanthemums. | Xiaoying Han Yuting Luo Jiaoyang Lin Huiying Wu Hao Sun Lijie Zhou Sumei Chen Zhiyong Guan Weimin Fang Fei Zhang Fadi Chen Jiafu Jiang | 2021 | Ornamental Plant Research2021，1，1： | 3 |
| 19 | Resistance switching for RRAM applications显示文摘Resistive random access memory (RRAM or ReRAM) is a non-volatile memory (NVM) technology that consumes minimal energy while offering sub-nanosecond switching. In addition, the data stability against high temperature and cycling wear is very robust, allowing new NVM applications in a variety of markets (au- tomotive, embedded, storage, RAM). Based on sudden conduction through oxide insulators, the characteristics of RRAM technology have still yet to be fully described. In this paper, we present our current understanding of this very promising technology. | CHEN Frederick T LEE HengYuan CHEN YuSheng HSU YenYa ZHANG LiJie CHEN PangShiu CHEN WeiSu GU PeiYi LIU WenHsing WANG SuMin TSAI ChenHan SHEU ShyhShyuan TSAI MingJinn HUANG Ru | 2011 | Science China(Information Sciences)2011，54，5： | 3 |
| 20 | Improvement on the interface properties of p-GaAs/n-InP heterojunction for wafer bonded four-junction solar cells显示文摘The p-GaAs/n-InP heterojunction was fabricated by direct wafer bonding technology. The optimized atomic level contact between GaAs and InP is critical for getting good ohmic contact and removing the bubbles or voids at the interface, which is helpful to enhance the efficiency of wafer bonded multi-junction solar cells. Through the surface megasonic cleaning and the plasma treatment, we have achieved the high quality bonding interface without bubbles or voids and with interface resistivity of about 0.1 ohms/cm^2. A GaInP/GaAs//InGaAsP/InGaAs 4-junction solar cell was prepared with the high efficiency of 34.4%(AM0)at 1 sun. | Mengyan Zhang Tao Ning Jie Chen Lijie Sun Lihua Zhou | 2019 | Journal of Materials Science & Technology2019，35，3： | 2 |
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