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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | High salt primes a specific activation state of macrophages, M(Na)显示文摘 | Wu-Chang Zhang Xiao-Jun Zheng Lin-Juan Du Jian-Yong Sun Zhu-Xia Shen Chaoji Shi Shuyang Sun Zhiyuan Zhang Xiao-qing Chen Mu Qin Xu Liu Jun Tao Lijun Jia Heng-yu Fan Bin Zhou Ying Yu Hao Ying Lijian Hui Xiaolong Liu Xianghua Yi Xiaojing Liu Lanjing Zhang Sheng-Zhong Duan | 2015 | Cell Research2015，25，8： | 15 |
| 3 | Remote sensing-based artificial surface cover classification in Asia and spatial pattern analysis显示文摘Artificial surfaces, characterized with intensive land-use changes and complex landscape structures, are important indicators of human impacts on terrestrial ecosystems. Without high-resolution land-cover data at continental scale, it is hard to evaluate the impacts of urbanization on regional climate, ecosystem processes and global environment. This study constructed a hierarchical classification system for artificial surfaces, promoted a remote sensing method to retrieve subpixel components of artificial surfaces from 30-m resolution satellite imageries(Globe Land30) and developed a series of data products of high-precision urban built-up areas including impervious surface and vegetation cover in Asia in 2010. Our assessment, based on multisource data and expert knowledge, showed that the overall accuracy of classification was 90.79%. The mean relative error for the impervious surface components of cities was 0.87. The local error of the extracted information was closely related to the heterogeneity of urban buildings and vegetation in different climate zones. According to our results, the urban built-up area was 18.18×104 km2, accounting for 0.59% of the total land surface areas in Asia; urban impervious surfaces were 11.65×104 km2, accounting for 64.09% of the total urban built-up area in Asia. Vegetation and bare soils accounted for 34.56% of the urban built-up areas. There were three gradients: a concentrated distribution, a scattered distribution and an indeterminate distribution from east to west in terms of spatial pattern of urban impervious surfaces. China, India and Japan ranked as the top three countries with the largest impervious surface areas, which respectively accounted for 32.77%, 16.10% and 11.93% of the urban impervious surface area of Asia. We found the proportions of impervious surface and vegetation cover within urban built-up areas were closely related to the economic development degree of the country and regional climate environment. Built-up areas in developed countries had relatively low impervious surface and high public green vegetation cover, with 50–60% urban impervious surfaces in Japan, South Korea and Singapore. In comparison, the proportion of urban impervious surfaces in developing countries is approaching or exceeding 80% in Asia. In general, the composition and spatial patterns of built-up areas reflected population aggregation and economic development level as well as their impacts on the health of the environment in the sub-watershed. | KUANG WenHui CHEN LiJun LIU JiYuan XIANG WeiNing CHI WenFeng LU DengSheng YANG TianRong PAN Tao LIU AiLin | 2016 | Science China Earth Sciences2016，59，9： | 12 |
| 4 | Immunotherapeutical Potential of Mycobacterium Vaccae on M. Tuberculosis Infection in Mice显示文摘Tuberculosis remains the worldwide infectious disease. To identify the therapeutic potential of M. vaccae in treating tuberculosis,M. vaccae was injected into Mycobacterium tuberculosis(M. tuberculosis) infected mice. The optimal dose of M. vaccae(22.5 μg/mouse) treated mice showed lower pathological change index,spleen weight index,lung weight index and vital M. tuberculosis count than those of the untreated group. Treatment with M. vaccae enhanced the percentages of CD3+ and CD4+ T cells,IFN-γ+CD4+ T cells,innate immune cells including NK cells,NK1.1+ T cells and γδ T cells,and reduced the percentage of IL-4+CD4+ T cells. Therefore,M. vaccae could protect the mice from M. tuberculosis infection and improved mouse innate and adaptive cell-mediated immunity,suggesting that M. vaccae is a potential immunotherapeutic agent in pulmonary tuberculosis. | Lijun Xu Yanyan Wang Xiaodong Zheng Xiangdong Gui Lifeng Tao Haiming Wei | 2009 | Cellular & Molecular Immunology2009，6，1： | 11 |
| 5 | Chronic Food Antigen-specific IgG-mediated Hypersensitivity Reaction as A Risk Factor for Adolescent Depressive Disorder显示文摘Major depressive disorder (MDD) is the most common nonfatal disease burden world-wide. Systemic chronic low-grade inflammation has been reported to be associated with MDD pro-gression by affecting monoaminergic and glutamatergic neurotransmission. However,whether various proinflammatory cytokines are abnormally elevated before the first episode of depression is still largely unclear. Here,we evaluated 184 adolescent patients who were experiencing their first episode of depressive disorder,and the same number of healthy individuals was included as con-trols. We tested the serum levels of high-sensitivity C-reactive protein (hs-CRP),tumor necrosis factor-α(TNF-α),IgE,14 different types of food antigen-specific IgG,histamine,homocysteine,S100 calcium-binding protein B,and diamine oxidase. We were not able to find any significant dif-ferences in the serum levels of hs-CRP or TNF-αbetween the two groups. However,the histamine level of the patients (12.35μM) was significantly higher than that of the controls (9.73μM,P<0.001,Mann–Whitney U test). Moreover,significantly higher serum food antigen-specific IgG positive rates were also found in the patient group. Furthermore,over 80% of patients exhibited prolonged food intolerance with elevated levels of serum histamine,leading to hyperpermeability of the blood–brain barrier,which has previously been implicated in the pathogen-esis of MDD. Hence,prolonged high levels of serum histamine could be a risk factor for depressive disorders,and antihistamine release might represent a novel therapeutic strategy for depression treatment. | Ran Tao Zhicheng Fu Lijun Xiao | 2019 | Genomics, Proteomics & Bioinformatics2019，17，2： | 11 |
| 6 | Mechanical properties and failure characteristics of fractured sandstone with grouting and anchorage显示文摘Based on uniaxial compression experimental results on fractured sandstone with grouting and anchorage, we studied the strength and deformation properties, the failure model, crack formation and evolution laws of fractured sandstone under different conditions of anchorage. The experimental results show that the strength and elastic modulus of fractured sandstone with different fracture angles are significantly lower than those of intact sandstone. Compared with the fractured samples without anchorage,the peak strength, residual strength, peak and ultimate axial strain of fractured sandstone under different anchorage increase by 64.5–320.0%, 62.8–493.0%, and 31.6–181.4%, respectively. The number of bolts and degree of pre-stress has certain effects on the peak strength and failure model of fractured sandstone. The peak strength of fractured sandstone under different anchorage increases to some extent, and the failure model of fractured sandstone also transforms from tensile failure to tensile–shear mixed failure with the number of bolts. The pre-stress can restrain the formation and evolution process of tensile cracks, delay the failure process of fractured sandstone under anchorage and impel the transformation of failure model from brittle failure to plastic failure. | Zong Yijiang Han Lijun Qu Tao Yang Shengqi | 2014 | International Journal of Mining Science and Technology2014，24，2： | 9 |
| 7 | Sintilimab versus docetaxel as second-line treatment in advanced or metastatic squamous non-small-cell lung cancer:an open-label,randomized controlled phase 3 trial(ORIENT-3)显示文摘Background:Treatment options for Chinese patients with locally advanced or metastatic squamous-cell non-small-cell lung cancer(sqNSCLC)after failure of first-line chemotherapy are limited.This study(ORIENT-3)aimed to evaluate the efficacy and safety of sintilimab versus docetaxel as second-line treatment in patients with locally advanced or metastatic sqNSCLC.Methods:ORIENT-3 was an open-label,multicenter,randomized controlled phase 3 trial that recruited patients with stage IIIB/IIIC/IV sqNSCLC after failure with first-line platinum-based chemotherapy.Patients were randomized in a 1:1 ratio to receive either 200 mg of sintilimab or 75 mg/m^(2) of docetaxel intravenously every 3 weeks,stratified by the Eastern Cooperative Oncology Group performance status.The primary endpoint was overall survival(OS)in the full analysis set(FAS).Secondary endpoints included progression-free survival(PFS),objective response rate(ORR),disease control rate(DCR),duration of response(DoR)and safety.Results:Between August 25,2017,and November 7,2018,290 patients were randomized.For FAS,10 patients fromthe docetaxel armwere excluded.Themedian OS was 11.79(n=145;95%confidence interval[CI],10.28-15.57)months with sintilimab versus 8.25(n=135;95%CI,6.47-9.82)months with docetaxel(hazard ratio[HR]:0.74;95%CI,0.56-0.96;P=0.025).Sintilimab treatment significantly prolonged PFS(median 4.30 vs.2.79 months;HR:0.52;95%CI,0.39-0.68;P<0.001)and showed higher ORR(25.50%vs.2.20%,P<0.001)and DCR(65.50%vs.37.80%,P<0.001)than the docetaxel arm.The median DoRwas 12.45(95%CI,4.86-25.33)months in the sintilimab arm and 4.14(95%CI,1.41-7.23)months in the docetaxel arm(P=0.045).Treatment-related adverse events of grade≥3were reported in 26(18.1%)patients in the sintilimab arm and 47(36.2%)patients in the docetaxel arm.Exploratory biomarker analysis showed potential predictive values of expression levels of two transcription factors,including OVOL2(HR:0.35;P<0.001)and CTCF(HR:3.50;P<0.001),for sintilimab treatment.Conclusions:Compared with docetaxel,sintilimab significantly improved the OS,PFS,and ORR of Chinese patients with previously treated locally advanced or metastatic sqNSCLC. | Yuankai Shi Lin Wu Xinmin Yu Puyuan Xing Yan Wang Jianying Zhou Airong Wang Jianhua Shi Yi Hu Ziping Wang Guangyu An Yong Fang Sanyuan Sun Caicun Zhou Changli Wang Feng Ye Xingya Li Junye Wang Mengzhao Wang Yunpeng Liu Yanqiu Zhao Ying Yuan Jifeng Feng Zhendong Chen Jindong Shi Tao Sun Gang Wu Yongqian Shu Qisen Guo Yi Zhang Yong Song Shucai Zhang Yuan Chen Wei Li Hongrui Niu Wenwei Hu Lijun Wang Jianan Huang Yang Zhang Ying Cheng Zhengdong Wu Bo Peng Jiya Sun Christoph Mancao Yanqi Wang Luyao Sun | 2022 | Cancer Communications2022，42，12： | 8 |
| 8 | Real-time compensation of phase drift for phase-encoded quantum key distribution systems显示文摘Phase drift is an inherent problem in phase-encoded quantum key distribution(QKD) systems.The current active phase trackingand compensation solutions cannot satisfy the requirements of a system with nonlinearity in phase modulation.This paper presents a four-phase scanning method,which is based on the quantitative analysis of the quantum bit error rate(QBER) from phasedrift and the performance requirements of phase compensation.By obtaining the four interference fringes and adjusting the codingmatrix of the system,this method automatically calculates the accurate driving voltages for the phase modulator.The implementation and experimental tests show that the proposed method can compensate phase drift caused by environmental changes and thesystem's nonlinearity,and is applicable to large-scale QKD networks. | ZHANG LiJun WANG YongGang YIN ZhenQiang CHEN Wei YANG Yang ZHANG Tao HUANG DaJun WANG Shuang LI FangYi HAN ZhengFu | 2011 | Chinese Science Bulletin2011，56，22： | 6 |
| 9 | The efficacy and safety of nimodipine in acute ischemic stroke patients with mild cognitive impairment: a double-blind, randomized,placebo-controlled trial显示文摘Nimodipine might be effective in subcortical vascular dementia(VaD). Its benefit in preventing further cognitive decline in patients with acute ischemic stroke(AIS) and vascular mild cognitive impairment(VaMCI) remains to be established. In this multicenter, double-blind trial, we randomly assigned 654 eligible patients to nimodipine 30 mg three times a day or placebo. The primary outcome was any cognitive decline defined by the changes on the Mini-Mental State Examination(DMMSE à3) or vascular AD assessment scale cognitive subscale(DADAS-cog ! 4) at 6 months. Secondary outcomes included any distribution shift of DADAS-cog, DMMSE or cognitive improvement defined by DADAS-cog à2, or DMMSE ! 0. The primary outcome in the nimodipine group and placebo group were similar for DMMSE à3(4.18% and 7.22%, respectively, P = 0.15) and DADAS-cog ! 4(8.36% and 8.93% respectively,P = 0.88). The distribution shift of DADAS-cog and DMMSE differed significantly between the two groups(P = 0.03 and P = 0.05 respectively). Cognitive improvement occurred in 55.4% in the nimodipine group and 43.6% in the placebo group measured by DADAS-cog à2(Odds Ratio, 1.54; 95% confidence interval[CI] 1.10–2.14, P < 0.01) or 84.0% and 74.6% respectively by DMMSE ! 0(Odds Ratio, 1.79; 95% CI 1.18–2.70, P < 0.01). Nimodipine was associated with better cognitive function in the memory domain. The adverse events rate was similar in two groups. This study is registered with ClinicalTrials.gov,NCT01220622. Nimodipine did not show benefit to prevent cognitive decline in AIS patients with VaMCI, but improved cognition moderately, especially measured in the memory domain. | Huaguang Zheng Yilong Wang Anxin Wang Hao Li David Wang Xingquan Zhao Penglian Wang Haipeng Shen Lijun Zuo Yuesong Pan Zixiao Li Xia Meng Xianwei Wang Weixiong Shi Yi Ju Liping Liu Kehui Dong Chunxue Wang Rubo Sui Rong Xue Xiaoping Pan Xiaoyua Niu Benyan Luo Yi Sui Huali Wang Tao Feng Yongjun Wang | 2019 | Science Bulletin2019，64，2： | 5 |
| 10 | Speciation, sources, and risk assessment of heavy metals in suburban vegetable garden soil in Xianyang City, Northwest China显示文摘Intensive anthropogenic activities can lead tosoil heavy metal contamination resulting in potential risksto the environment and to human health. To reveal theconcentrations, speciation, sources, pollution level, andecological risk of heavy metals in vegetable garden soil, atotal of 136 soil samples were collected from threevegetable production fields in the suburbs of XianyangCity, Northwest China. These samples were analyzed byinductively coupled plasma- atomic emission spectrometryand atomic fluorescence spectrometry. The results showedthat the mean concentrations of Cd, Co, Cu, Mn, Pb, Zn,and Hg in vegetable garden soil were higher than thecorresponding soil element background values of ShaanxiProvince. The heavy metals studied in vegetable gardensoil were primarily found in the residual fraction,averaging from 31.26% (Pb)to 90.23% (Cr). Consideringthe non-residual fractions, the mobility or potential riskwas in the order of Pb (68.74%)〉 Co (60.54%)〉 Mn(59.28%)〉Cd (53.54%)〉〉Ni (23.36%)〉Zn(22.73%) 〉 Cu (14.93%) 〉 V (11.81%) 〉 Cr (9.78%). Cr,Mn, Ni, V, and As in the studied soil were related to soil-forming parent materials, while Cu, Hg, Zn, Cd, Co, andPb were associated with the application of plastic films,fertilizers, and pesticides, as well as traffic emissions andindustrial fumes. Cr, Ni, V, and As presented lowcontamination levels, whereas Co, Cu, Mn, Pb, and Znlevels were moderate, and Cd and Hg were high.Ecological risk was low for Co, Cr, Cu, Mn, Pb, Zn, andAs, with high risk observed for Cd and Hg. The overallpollution level and ecological risk of these heavy metalswere high. | Lijun WANG Wendong TAO Richard C. SMARDON Xue XU Xinwei LU | 2018 | Frontiers of Earth Science2018，12，2： | 5 |
| 11 | Advanced non-precious electrocatalyst of the mixed valence CoO_x nanocrystals supported on N-doped carbon nanocages for oxygen reduction显示文摘Taking advantage of the nitrogen(N)-participation and large surface area of N-doped carbon nanocages(NCNCs),the Co Ox nanocrystals are conveniently immobilized onto the NCNCs with high dispersion.The Co Ox/NCNCs hybrid exists in the mixed valence with predominant Co O over Co3O4 and demonstrates superb oxygen reduction reaction activity and stability remaining^94%current density even after operation over 100 h.These results suggest a promising strategy to develop advanced electrocatalysts with the novel NCNCs or even beyond. | Sheng Chen Liwei Wang Qiang Wu Xiang Li Yu Zhao Hongwei Lai Lijun Yang Tao Sun Yi Li Xizhang Wang Zheng Hu | 2015 | Science China Chemistry2015，58，1： | 5 |
| 12 | Age-Related Reduction in Cortical Thickness in First-Episode Treatment-Na?ve Patients with Schizophrenia显示文摘Substantial evidence supports the neurodevelopmental hypothesis of schizophrenia.Meanwhile,progressive neurodegenerative processes have also been reported,leading to the hypothesis that neurodegeneration is a characteristic component in the neuropathology of schizophrenia.However,a major challenge for the neurodegenerative hypothesis is that antipsychotic drugs used by patients have profound impact on brain structures.To clarify this potential confounding factor,we measured the cortical thickness across the whole brain using highresolution T1-weighted magnetic resonance imaging in 145 first-episode and treatment-naive patients with schizophrenia and 147 healthy controls.The results showed that,in the patient group,the frontal,temporal,parietal,and cingulate gyri displayed a significant age-related reduction of cortical thickness.In the control group,age-related cortical thickness reduction was mostly located in the frontal,temporal,and cingulate gyri,albeit to a lesser extent.Importantly,relative to healthy controls,patients exhibited a significantly smaller age-related cortical thickness in the anterior cingulate,inferior temporal,and insular gyri in the right hemisphere.These results provide evidence supporting the existence of neurodegenerative processes in schizophrenia and suggest that these processes already occur in the early stage of the illness. | Yin Lin Mingli Li Yi Zhou Wei Deng Xiaohong Ma Qiang Wang Wanjun Guo Yinfei Li Lijun Jiang Xun Hu Nanyin Zhang Tao Li | 2019 | Neuroscience Bulletin2019，35，4： | 5 |
| 13 | Clinical curative effect of fuzi-cake-separated moxibustion for preventing dysuria after operation for lower limb fracture显示文摘OBJECTIVE: To assess the clinical curative effect of fuzi-cake-separated moxibustion at Zhongji(CV 3)and Guanyuan(CV 4) for preventing dysuria after internal fixation of lower limb fractures.METHODS: Sixty patients conforming to the inclusion standards were randomly divided into a treatment group(n=30) and a control group(n=30).Fuzi-cake-separated moxibustion was performed at Guanyuan(CV 4) and Zhongji(CV 3), 20 min at a time, twice a day, for 3 days before operation in the treatment group. No fuzi-cake-separated moxibustion was performed in the control group. After treatment, the score for symptoms of first urination, urinary time, urinary volume, 24 h remaining urinary volume, incidence of uroschesis, and rate of controlling dysuria were compared to evaluate the curative effect of preventing post-operative dysuria.RESULTS: The score for symptoms of first urination,24 h remaining urinary volume(maximum 120 m L vs 250 m L, and less than 10 m L in 24 cases vs 15 cases), and the rate of controlling dysuria(83.34% vs30%) were significantly better(P<0.05, P<0.05, and P<0.001, respectively) in the treatment compared with the control group. There was no statistical difference(P>0.05) between the two groups in first post-operative urinary time, urinary volume, or incidence of 24 h uroschesis.CONCLUSION: Fuzi-cake-separated moxibustion at Zhongji(CV 3) and Guanyuan(CV 4) can better prevent post-operative dysuria, effectively promote the functional restoration of the urinary bladder,and control the incidence of post-operative dysuria. | Yan Yue Lijun Tao Jianqiao Fang Qi Xie Shaofeng He Chunxia Huang Xueming Yang | 2014 | Journal of Traditional Chinese Medicine2014，34，5： | 4 |
| 14 | Microstructure and mechanical properties of Fe_xCoCrNiMn high-entropy alloys显示文摘The microstructure and tensile properties of FexCo Cr Ni Mn high-entropy alloys(HEAs) were investigated.It was found that the FexCo Cr Ni Mn HEA has a single face-centered cubic(fcc) structure in a wide range of Fe content. Further increasing the Fe content endowed the FexCo Cr Ni Mn alloys with an fcc/bodycentered cubic(bcc) dual-phase structure. The yield strength of the FexCo Cr Ni Mn HEAs slightly decreased with the increase of Fe content. An excellent combination of strength and ductility was achieved in the FexCo Cr Ni Mn HEA with higher Fe content, which can be attributed to the outstanding deformation coordination capability of the fcc/bcc dual phase structure. | Tao Zhang Lijun Xin Fufa Wu Rongda Zhao Jun Xiang Minghua Chen Songshanjiang Yongjiang Huang Shunhua Chen | 2019 | Journal of Materials Science & Technology2019，35，10： | 4 |
| 15 | Halide Homogenization for High-Performance Blue Perovskite Electroluminescence显示文摘Metal halide perovskite light-emitting diodes(LEDs)have achieved great progress in recent years.However,bright and spectrally stable blue perovskite LED remains a significant challenge.Three-dimensional mixed-halide perovskites have potential to achieve high brightness electroluminescence,but their emission spectra are unstable as a result of halide phase separation.Here,we reveal that there is already heterogeneous distribution of halides in the as-deposited perovskite films,which can trace back to the nonuniform mixture of halides in the precursors.By simply introducing cationic surfactants to improve the homogeneity of the halides in the precursor solution,we can overcome the phase segregation issue and obtain spectrally stable single-phase blueemitting perovskites.We demonstrate efficient blue perovskite LEDs with high brightness,e.g.,luminous efficacy of 4.7,2.9,and 0.4 lmW^(-1) and luminance of over 37,000,9,300,and 1,300 cdm^(-2) for sky blue,blue,and deep blue with Commission Internationale de l’Eclairage(CIE)coordinates of(0.068,0.268),(0.091,0.165),and(0.129,0.061),respectively,suggesting real promise of perovskites for LED applications. | Lu Cheng Chang Yi Yunfang Tong Lin Zhu Gunnar Kusch Xiaoyu Wang Xinjiang Wang Tao Jiang Hao Zhang Ju Zhang Chen Xue Hong Chen Wenjie Xu Dawei Liu Rachel AOliver Richard HFriend Lijun Zhang Nana Wang Wei Huang Jianpu Wang | 2020 | Research2020，，1： | 4 |
| 16 | Proteomics: addressing the challenges of multiple myeloma显示文摘多重骨髓瘤(公里) 是说明 13% 所有 hematologic 癌症的严重地区分的 B 淋巴细胞的恶意。尽管有在治疗学象重要进展一样描述公里的分子的生物学的很多知识,这疾病仍然保持医不好。因为蛋白质管理细胞的结构和生物功能,大量精选的 proteomic 为增加我们这疾病的理解接近抓住伟人诺言,例如由调查蛋白质表示的动态性质,细胞并且在两个的 subcellular 分发, translational 以后修正,和相互作用细胞并且 subcellular 层次。这评论的目的是介绍在公里的学习有潜在的应用的可得到、新兴的 proteomic 技术并且加亮公里的 proteomic 研究的当前的地位。迄今为止,尽管在公里有一小部分 proteomic 研究,执行的那些关于公里诊断和治疗提供了珍贵信息。proteomic 技术的潜在的未来申请被期望为临床医生在公里诊断,个性化的治疗设计和治疗反应监视提供新大街。 | Feng Ge Shengce Tao Lijun Bi Zhiping Zhang Xian'En Zhang | 2011 | Acta Biochimica et Biophysica Sinica2011，43，2： | 4 |
| 17 | Rapid and simultaneous analysis of multiple wine quality indicators through near-infrared spectroscopy with twice optimization for wavelength model显示文摘Alcohol,total sugar,total acid,and total phenol contents are the main indicators of wine quality detection.This study aims to establish simultaneous analysis models for the four indicators through near-infrared(NIR)spectroscopy with wavelength optimization.A Norris derivative filter(NDF)platform with multiparameter optimization was established for spectral pretreatment.The optimal parameters(i.e.,derivative order,number of smoothing points,and number of differential gaps)were(2,9,3)for alcohol,(1,19,5)for total sugar,(1,17,11)for total acid,and(1,1,1)for total phenol.The equidistant combinationpartial least squares(EC-PLS)was used for large-scale wavelength screening.The wavelength step-by-step phaseout PLS(WSP-PLS)and exhaustive methods were used for secondary optimization.The final optimization models for the four indicators included 7,10,15,and 13 wavelengths located in the overtone or combination regions,respectively.In an independent validation,the root mean square errors,correlation coefficient for prediction(i.e.,SEP and RP),and ratio of performance-to-deviation(RPD)were 0.41 v/v,0.947,and 3.2 for alcohol;1.48 g/L,0.992,and 6.8 for total sugar;0.68 g/L,0.981,and5.1 for total acid;and 0.181 g/L,0.948,and 2.9 for total phenol.The results indicate high correlation,low error,and good overall prediction performance.Consequently,the established reagent-free NIR analytical models are important in the rapid and real-time quality detection of the wine fermentation process and finished products.The proposed wavelength models provide a valuable reference for designing small dedicated instruments. | Jiemei CHEN Sixia LIAO Lijun YAO Tao PAN | 2021 | Frontiers of Optoelectronics2021，14，3： | 2 |
| 18 | CsPb(I_(x)Br_(1-x))_(3) solar cells显示文摘Owing to its nice performance, low cost, and simple solution-processing, organic-inorganic hybrid perovskite solar cell(PSC) becomes a promising candidate for next-generation high-efficiency solar cells.The power conversion efficiency(PCE) has boosted from 3.8% to 25.2% over the past ten years. Despite the rapid progress in PCE, the device stability is a key issue that impedes the commercialization of PSCs. Recently, all-inorganic cesium lead halide perovskites have attracted much attention due to their better stability compared with their organic-inorganic counterpart. In this progress report, we summarize the properties of CsPb(IxBr1-x)3 and their applications in solar cells. The current challenges and corresponding solutions are discussed. Finally, we share our perspectives on CsPb(IxBr1-x)3 solar cells and outline possible directions to further improve the device performance. | Xue Jia Chuantian Zuo Shuxia Tao Kuan Sun Yixin Zhao Shangfeng Yang Ming Cheng Mingkui Wang Yongbo Yuan Junliang Yang Feng Gao Guichuan Xing Zhanhua Wei Lijun Zhang Hin-Lap Yip Mingzhen Liu Qing Shen Longwei Yin Liyuan Han Shengzhong Liu Lianzhou Wang Jingshan Luo Hairen Tan Zhiwen Jin Liming Ding | 2019 | Science Bulletin2019，64，20： | 2 |
| 19 | Environmental biogeochemical behaviors of rare earth elements in soil–plant systems显示文摘 | Tao Liang Shen Zhang Lijun Wang Hsiang-Te Kung Yuqi Wang Aitang Hu Shiming Ding | 2005 | Environmental Geochemistry and Health2005，，4： | 2 |
| 20 | Sirolimus combined with oseltamivir and corticosteroid treatment for a puerpera with severe pneumonia caused by 2009 pandemic H1N1:A case report显示文摘Severe pneumonia in patients infected with the 2009 pandemic H1N1(pH1N1)virus was partially attributed to excessive immune response.Anti-virus treatment for these patients was insufficient.Here we reported the therapy effect of sirolimus,an immunosuppressor,combined with oseltamivir and corticosteroid for a puerpera with severe pneumonia caused by pH1N1 virus.This patient has infected with the pH1N1 virus in late pregnancy,and antiviral therapy was not implemented timely.She developed severe pneumonia and ARDS rapidly and need receive a cesarean section on the 39th week after pregnancy.After giving birth to a healthy baby,she received a combination of oseltamivir,sirolimus and corticosteroid,and improved in the following days.Moreover,the cytokines in serum and viral loads in BALF decreased significantly.She recovered without infectious symptoms and was discharged.Sirolimus combined with oseltamivir and corticosteroid is likely responsible for lowering the viral loads,reducing the patient's cytokine level,and further improving her clinical outcomes.It provides evidence that adjuvant treatment was beneficial to patients with severe pneumonia induced by the pH1N1 virus. | Lijun Suo Xiaofeng Yu Yongfeng Hu Hongyun Cao Xiaohui Zou Peiquan Wang Tao Xu Xiangzhi Zhou Yexin Wu Lili Ren Bo Liu Bin Cao | 2021 | Biosafety and Health2021，3，6： | 2 |
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