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| 1 | Standardized Operational Protocol for Human Brain Banking in China显示文摘With the progress of society, there is an increasing need to tackle disorders of the central nervous system. Human brain tissue, unlike animal tissues, is an irreplaceable resource for the study of neurological diseases (1)Aimed at scientific research and education, the roles of human brain tissue repositories are to acquire brain tissue from donors, prepare, process, and preserve collected samples,provide tissue to specific eligible facilities, and determine the characteristics of each tissue sample. | Wenying Qiu Hanlin Zhang Aimin Bao Keqing Zhu Yue Huang Xiaoxin Yan Jing Zhang Chunjiu Zhong Yong Shen Jiangning Zhou Xiaoying Zheng Liwei Zhang Yousheng Shu Beisha Tang Zhenxin Zhang Gang Wang Ren Zhou Bing Sun Changlin Gong Shumin Duan Chao Ma | 2019 | Neuroscience Bulletin2019,35,2: | 6 |
| 2 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021,31,12: | 5 |
| 3 | A predictive functional control algorithm for multivariable systems with time delay显示文摘To improve the dynamic characteristics and the coupling capability,a new predictive functional control algorithm is proposed for strong coupling multivariable systems with time delay,which combines predictive functional control and decoupling control.First,a decoupling control algorithm is proposed,in which frst-order models with time delay are established by analyzing the amplitude-frequency and phase-frequency characteristics of the decoupled subject.Then,a controller is designed for the single-variable subjects after decoupling based on the principles of predictive functional control.The simulation results show that this proposed algorithm has less online computation time and faster tracking.It can provide a more effective control for complex multivariable systems. | Lei ZHOU Shumin FEI Jiacai HUANG Junyong ZHAI | 2013 | 控制理论与应用(英文版)2013,11,4: | 4 |
| 4 | Time-sequential color code division multiplexing holographic display with metasurface显示文摘Color metasurface holograms are powerful and versatile platforms for modulating the amplitude,phase,polarization,and other properties of light at multiple operating wavelengths.However,the current color metasurface holography can only realize static manipulation.In this study,we propose and demonstrate a multiplexing metasurface technique combined with multiwavelength code-division multiplexing(CDM)to realize dynamic manipulation.Multicolor code references are utilized to record information within a single metasurface and increase the information capacity and security for anticracks.A total of 48 monochrome images consisting of pure color characters and multilevel color video frames were reconstructed in dual polarization channels of the birefringent metasurface to exhibit high information density,and a video was displayed via sequential illumination of the corresponding code patterns to verify the ability of dynamic manipulation.Our approach demonstrates significant application potential in optical data storage,optical encryption,multiwavelengthversatile diffractive optical elements,and stimulated emission depletion microscopy. | Xin Li Qinmiao Chen Xue Zhang Ruizhe Zhao Shumin Xiao Yongtian Wang Lingling Huang | 2023 | Opto-Electronic Advances2023,6,8: | 3 |
| 5 | Relationship between phytoplankton composition and environmental factors in the surface waters of southern South China Sea in early summer of 2009显示文摘Horizontal distributions of phytoplankton abundance,species composition as well as environmental factors were investigated in the surface waters of southern South China Sea(SCS) in early summer(May 16 to June 7) of 2009.In most areas of southern SCS,the concentrations of nitrogen and phosphorus were very low and DIN/DIP ratios usually were lower than the Redfield N/P Ratio of 16:1.Nitrogen nutrients were significant lower in the upwelling region off Vietnam.A total of 144 taxa of phytoplankton were identified in the study area.The dominant genera were Prorocentrum,Gonyaulax,Gyrodinium,Scrippsiella and Chaetoceros,respectively.Spatial patterns of early-summer phytoplankton abundance and species composition should be mainly controlled by the upwelling off Vietnam and the discharge of Mekong River in the southern SCS.Diatoms dominated in the nutritious Mekong River Estuary or upwelling region off Vietnam;while dinoflagellates dominated in the oligotrophic pelagic region.The canonical correspondence analysis(CCA) indicates that most of diatoms favor higher levels of silicate and phosphorus,as well as lower temperature;while most of dinoflagellates favor the lower silicate and phosphorous and higher temperature.Correlation and CCA results indicate that silicate,nitrate and temperature were the most relevant environmental factors to regulate the horizontal pattern of early-summer phytoplankton in the surface waters of southern SCS. | KE Zhixin TAN Yehui HUANG Liangmin ZHANG Jianlin LIAN Shumin | 2012 | Acta Oceanologica Sinica2012,31,3: | 3 |
| 6 | Bi Nanoparticles Anchored in N-Doped Porous Carbon as Anode of High Energy Density Lithium Ion Battery显示文摘A novel bismuth–carbon composite, in which bismuth nanoparticles were anchored in a nitrogen-doped carbon matrix(Bi@NC), is proposed as anode for high volumetric energy density lithium ion batteries(LIBs).Bi@NC composite was synthesized via carbonization of Zn-containing zeolitic imidazolate(ZIF-8) and replacement of Zn with Bi, resulting in the N-doped carbon that was hierarchically porous and anchored with Bi nanoparticles. The matrix provides a highly electronic conductive network that facilitates the lithiation/delithiation of Bi.Additionally, it restrains aggregation of Bi nanoparticles and serves as a buffer layer to alleviate the mechanical strain of Bi nanoparticles upon Li insertion/extraction.With these contributions, Bi@NC exhibits excellent cycling stability and rate capacity compared to bare Bi nanoparticles or their simple composites with carbon. This study provides a new approach for fabricating high volumetric energy density LIBs. | Yaotang Zhong Bin Li Shumin Li Shuyuan Xu Zhenghui Pan Qiming Huang Lidan Xing Chunsheng Wang Weishan Li | 2018 | Nano-Micro Letters2018,10,4: | 3 |
| 7 | Rapidly developable therapeutic-grade equine immunoglobulin against the SARS-CoV-2 infection in rhesus macaques显示文摘Dear Editor,The unprecedented COVID-19 pandemic caused by SARS-CoV-2 remains ongoing,but there is a lack of fully effective treatments.Convalescent plasma-derived hyperimmune globulins have been a safe and effective treatment but restricted by the difficulties in obtaining sufficient plasma with high antibody titers from a large number of recovered patients.Heterologous antibodies,particularly equine antibodies,have been widely used for decades as the therapeutics against some viral infections or as antivenoms.1 Equine antibodies could be rapidly developed and manufactured into therapeutic antibodies in large quantities under WHO standardized guidelines.Here we explored the development of equine antibody-derived F(ab′)2 as an option to treat COVID-19 by targeting the receptor-binding domain(RBD)of the viral spike protein that is essential for the viral entry into the host cells.2 We observed excellent neutralization titers of the F(ab′)2 in vitro and high potency against SARS-CoV-2 infection in the nonhuman primate rhesus macaques. | Xiaolei Liu Yi Liu Xuemin Jin Zhanlong He Zhen Huang Shumin Sun Yuwei Gao Jingyu Li Qin Ning Zhongping Xie Ningyi Jin Mingyuan Liu | 2022 | Signal Transduction and Targeted Therapy2022,7,8: | 2 |
| 8 | A molecular roadmap for induced multi-lineage transdifferentiation of fibroblasts by chemical combinations显示文摘 | Xiaoping Han Hao Yu Daosheng Huang Yang Xu Assieh Saadatpour Xia Li Lengmei Wang Jie Yu Luca Pinello Shujing Lai Mengmeng Jiang Xueying Tian Fen Zhang Yanhong Cen Yuko Fujiwara Wei Zhu Bin Zhou Tianhua Zhou Hongwei Ouyang Jianan Wang Guo-Cheng Yuan Shumin Duan Smart H Orkin Guoji Guo | 2017 | Cell Research2017,27,3: | 2 |
| 9 | Integrating Pronunciation into Chinese-Vietnamese Statistical Machine Translation显示文摘Statistical machine translation for low-resource language suffers from the lack of abundant training corpora. Several methods, such as the use of a pivot language, have been proposed as a bridge to translate from one language to another. However, errors will accumulate during the extensive translation pipelines. In this paper,we propose an approach to low-resource language translation by exploiting the pronunciation correlations between languages. We find that the pronunciation features can improve both Chinese-Vietnamese and VietnameseChinese translation qualities. Experimental results show that our proposed model yields effective improvements,and the translation performance(bilingual evaluation understudy score) is improved by a maximum value of 1.03. | Anh Tran Huu Heyan Huang Yuhang Guo Shumin Shi Ping Jian | 2018 | Tsinghua Science and Technology2018,23,6: | 2 |
| 10 | Characterization of surface composition of platinum and ruthenium nanoalloys dispersed on active carbon显示文摘 | Huang Shengyang Chang Shumin Yeh Chuin-Tih | 2006 | J Phys Chem B2006,110,1: | 1 |
| 11 | Miocene palynomorphs of Taiwan (Ⅶ)-Additional note on gymnospermous palynomorphs显示文摘 | Huang Tsengchieng | 1981 | Taiwania1981,26,: | 1 |
| 12 | Distribution patterns of appendicularians and copepods and their relationship on the northwest continental shelf of South China Sea during summer显示文摘The potential suppression of copepods on appendicularians was found in field and experimental conditions. The abundance and distribution of appendicularians and planktonic copepods were studied with reference to their correlations during summer on the northwest continental shelf of the South China Sea (SCS). Based on the topography and water mass of the surveyed region, it was divided into three sub-regions: Region I (inshore waters of the east Leizhou Peninsula) with low temperature, salinity and high chlorophyll a (Chl a) concentration, Region II (inshore waters of the east and southeast Hainan Island) with low temperature, high salinity and moderate Chl a concentration and Region III (offshore waters from the Leizhou Peninsula to Hainan Island) with high temperature, high salinity and low Chl a concentration. The species richness of appendicularians and copepods increased from the inshore to offshore waters, and high values were observed in Region III. The distribution of appendicularian and copepod abundance decreased generally from the inshore to offshore waters, with the highest values at Region I. Our results suggest that the distribution patterns of appendicularians and copepods differed significantly, as a result of the influence of physical and biological factors. The negative impact of pelagic copepods on appendicularians was not found based on in situ data in the northwest continental shelf of SCS. | LI Kaizhi YIN Jianqiang HUANG Liangmin LIAN Shumin ZHANG Jianlin | 2012 | Acta Oceanologica Sinica2012,31,5: | 1 |
| 13 | Discussion on a new paradigm of endogenous security towards 6G networks显示文摘The sixth-generation mobile communication(6G)networks will face more complex endogenous security problems,and it is urgent to propose new universal security theories and establish new practice norms to deal with theªunknown unknownºsecurity threats in cyberspace.This paper first expounds the new paradigm of cyberspace endogenous security and introduces the vision of 6G cyberspace security.Then,it analyzes the security problems faced by the 6G core network,wireless access network,and emerging associated technologies in detail,as well as the corresponding security technology development status and the integrated development of endogenous security and traditional security.Furthermore,this paper describes the relevant security theories and technical concepts under the guidance of the new paradigm of endogenous security. | Xinsheng JI Jiangxing WU Liang JIN Kaizhi HUANG Yajun CHEN Xiaoli SUN Wei YOU Shumin HUO Jing YANG | 2022 | Frontiers of Information Technology & Electronic Engineering2022,23,10: | 1 |
| 14 | Effect of stimulated weightlessness on gut flora in rat显示文摘 | BAI Shumin HUANG Jiming ZHU Debing | 2001 | J China Microecology2001,13,6: | 1 |
| 15 | A Methodology Framework for Regional Land-use Change Studies based on Landsat TM images: A Case Study in Northeast China显示文摘Land-use change is an important aspect of global environment change. It is, in a sense, the direct result of human activities influencing our physical environment. This paper analyzed the land-use change in Northeast China during 1985-2000 based on Landsat TM images. It divides Northeast China into five land-use zones based on the dynamic degree model of land-use: woodland/grassland-arable land conversion zone, dry land-paddy field conversion zone; urban expansion zone, interlocked zone of farming and pasturing and reclamation and abandon zone. The findings include the obvious increase of cropland area, paddy field and dry land increased by 75 and 276 thousand hm2 respectively; urban areas expanded rapidly, areas of town and rural residence increased by 76.8 thousand hm2; areas of forests and grassland decreased sharply with the amounts of 1399 and 1521 thousand hm2 respectively; areas of water body and unused land increased by 148 and 514 thousand hm2 respectively. This paper also discusses the | Deng Xiangzheng , Huang Shumin , Zhan Jinyan & Zhao Tao Center for Chinese Agricultural Policy, Chinese Academy of Sciences, Beijing 100101 Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101 Anthropology Department, Iowa State University, Ames, Iowa 50010-1050, USA, | 2004 | Chinese Journal of Population,Resources and Environment2004,2,4: | 0 |
| 16 | Improving Parallel Corpus Quality for Chinese-Vietnamese Statistical Machine Translation显示文摘The performance of a machine translation system heavily depends on the quantity and quality of the bilingual language resource. However,getting a parallel corpus,which has a large scale and is of high quality,is a very difficult task especially for low resource languages such as Chinese-Vietnamese. Fortunately,multilingual user generated contents( UGC),such as bilingual movie subtitles,provide us access to automatic construction of the parallel corpus. Although the amount of UGC parallel corpora can be considerable,the original corpus is not suitable for statistical machine translation( SMT) systems. The corpus may contain translation errors,sentence mismatching,free translations,etc. To improve the quality of the bilingual corpus for SMT systems,three filtering methods are proposed: sentence length difference,the semantic of sentence pairs,and machine learning. Experiments are conducted on the Chinese to Vietnamese translation corpus.Experimental results demonstrate that all the three methods effectively improve the corpus quality,and the machine translation performance( BLEU score) can be improved by 1. 32. | Huu-anh Tran Yuhang Guo Ping Jian Shumin Shi Heyan Huang | 2018 | Journal of Beijing Institute of Technology2018,27,1: | 0 |
| 17 | On the non-synchronous rotation of binary systems显示文摘During the evolution of the binary system,many physical processes occur,which can influence the orbital angular velocity and the spin angular velocities of the two components,and influence the non-synchronous or synchronous rotation of the system.These processes include the transfer of masses and angular momentums between the component stars,the loss of mass and angular momentum via stellar winds,and the deformation of the structure of component stars.A study of these processes indicates that they are closely related to the combined effects of tide and rotation.This means,to study the synchronous or non-synchronous rotation of binary systems,one has to consider the contributions of different physical processes simultaneously,instead of the tidal effect alone.A way to know whether the rotation of a binary system is synchronous or non-synchronous is to calculate the orbital angular velocity and the spin angular velocities of the component stars.If all of these angular velocities are equal,the rotation of the system is synchronous.If not,the rotation of the system is non-synchronous.For this aim,a series of equations are developed to calculate the orbital and spin angular velocities.The evolutionary calculation of a binary system with masses of 10M⊙+6M⊙shows that the transfer of masses and angular momentums between the two components,and the deformation of the components structure in the semidetached or in the contact phase can change the rotation of the system from synchronous into non-synchronous rotation. | LI ZhiXiong HUANG RunQian WANG ShuMin | 2014 | Science China(Physics,Mechanics & Astronomy)2014,57,6: | 0 |
| 18 | Weighted Aggregator for the Open-World Knowledge Graph Completion显示文摘Open-world knowledge graph completion aims to find a set of missing triples through entity description,where entities can be either in or out of the graph.However,when aggregating entity description’s word embedding matrix to a single embedding,most existing models either use CNN and LSTM to make the model complex and ineffective,or use simple semantic averaging which neglects the unequal nature of the different words of an entity description.In this paper,an aggregator is proposed,adopting an attention network to get the weights of words in the entity description.This does not upset information in the word embedding,and make the single embedding of aggregation more efficient.Compared with state-of-the-art systems,experiments show that the model proposed performs well in the open-world KGC task. | Yueyang Zhou Shumin Shi Heyan Huang | 2020 | 国际计算机前沿大会会议论文集2020,,1: | 0 |
| 19 | Utilizing Crowdsourcing for the Construction of Chinese-Mongolian Speech Corpus with Evaluation Mechanism显示文摘Crowdsourcing has been used recently as an alternative to traditional costly annotation by many natural language processing groups. In this paper, we explore the use of Wechat Official Account Platform (WOAP) in order to build a speech corpus and to assess the feasibility of using WOAP followers (also known as contributors) to assemble speech corpus of Mongolian. A Mongolian language qualification test was used to filter out potential non-qualified participants. We gathered natural speech recordings in our daily life, and constructed a Chinese-Mongolian Speech Corpus (CMSC) of 31472 utterances from 296 native speakers who are fluent in Mongolian, totalling 30.8 h of speech. Then,an evaluation experiment was performed, in where the contributors were asked to choose a correct sentence from a multiple choice list to ensure the high-quality of corpus. The results obtained so far showed that crowdsourcing for constructing CMSC with an evaluation mechanism could be more effective than traditional experiments requiring expertise. | Rihai Su Shumin Shi Meng Zhao Heyan Huang | 2017 | 国际计算机前沿大会会议论文集2017,,2: | 0 |
| 20 | Exponential stability and L_(2) gain analysis of switched distributed parameter systems with time delay显示文摘The present paper is concerned with stability and L_(2) gain analysis of switched distributed parameter system(SDPS)with time delay.First,exponential stability is discussed,and the state decay estimate of the system is explicitly given by using linear matrix inequalities(LMIs)incorporating with the average dwell time(ADT)method.Second,L_(2) gain analysis is also studied.At last,illustrative examples are given to show the effectiveness of the proposed method.The main contribution of the paper is:some criteria of exponential stability and L_(2) gain for multiple-input multiple-output(MIMO)switched PDE are developed in the form of LMIs and ADT signal for the first time.The advantage of the work is we generalize the application range of the related research.The proposed method is expected to provide an effective tool for stability and H∞control analysis of SDPS. | Leping Bao Pu Huang Shumin Fei | 2021 | Journal of Control and Decision2021,8,4: | 0 |