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| 1 | Effect of modified Taohongsiwu decoction on patients with chemotherapy-induced hand-foot syndrome显示文摘OBJECTIVE:To observe the effect of the Traditional Chinese Medicine,modified Taohongsiwu decoction,versus pyridoxine on patients with hand-foot syndrome(HFS)from capecitabine,sorafenib,and gefitinib chemotherapy for gastric,lung,breast,colon,or rectal cancer.Also,to compare quality of life of patients in each group.METHODS:Patients were assigned randomly to group A or B.Group A was given modifiedTaohongsiwu decoction to soak hands and feet for 30 min,once daily.Group B was given 100 mg pyridoxine orally,twice daily.After a 2-week treatment,thetherapeutic effect was assessed by observing three major symptoms,including pain,ulceration,and muscular atrophy.This was assessed with the HFS-14 questionnaire.RESULTS:Significant differences were observed between the two groups in pain relief,and improvement of daily life,walking,and interpersonal communication(P<0.01).No significant differences in driving ability or interpersonal relationships were found.After 2 weeks,the effective rate was 88.3%in group A,which was significantly higher than the50%in group B(P=0.00).CONCLUSION:Modified Taohongsiwu decoction is effective in the treatment of patients with HFS.It improves patients'quality of life according to the HFS-14. | Changlin Zhao Jia Chen Bin Yu Xianlin Wu Congqi Dai Chang Zhou Xiaoyin Chen | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 18 |
| 2 | Novel hydrogen storage properties of palladium nanocrystals activated by a pentagonal cyclic twinned structure显示文摘研究人员们看起来忽视了雏晶的一种特殊形式,五角的周期的 twinning,明显的二维的格子扩大在存在导致新奇 physicalchemical 性质在几何、电子的结构与变化联系了。在 Pd nanocrystals 把氢的存储和版本用作一根探针,我们发现了五角的周期的孪生的 Pd nanocrystals 有的那 icosahedral 不同的氢存储性质由于二维的格子扩大,与那些相当不同八面的单个水晶的对应物。另外,在五角的周期的孪生的 Pd nanocrystals 的二维的格子扩大在电子结构引起一个变化,它导致在 PdH x 五角的周期的孪生的 nanocrystals。 | Huang Huang Shixiong Bao Qiaoli Chen Yanan Yang Zhiyuan Jiang Qin Kuang Xiaoyin Wu Zhaoxiong Xie Lansun Zheng | 2015 | Nano Research2015，8，8： | 7 |
| 3 | Mechanism and effect of Shijueming (Concha Haliotidis) on serum calcium in spontaneously hypertensive rats显示文摘OBJECTIVE: To observe the impact of Shijueming (Concha Haliotidis) on spontaneously hypertensive rats via blood pressure, serum calcium, vascular smooth muscle membrane L-type calcium channel α1 C subunit (CaL-α1C), plasma membrane calcium-ATPase (PMCA) mRNA expression, and the L-type calcium channel in vascular smooth muscle cells. METHODS:Twelve-week-old male rats with spontaneous hypertension were divided into three groups: a Shijueming (Concha Haliotidis) group (group 1), a nifedipine group (group 2), and a distilled water group (group 3). All were given a four-week treatment. Blood pressure and dissociative serum calcium were examined before treatment. Blood pressure was taken every week during treatment. Atomic absorption spectrometry was used to examine dissociative serum calcium. Re-verse transcription-polymerase chain reaction was used to examine the expression of CaL-α1C and PM-CA1 mRNA. The patch clamp technique was used to examine the electrophysiological characteristics of the vascular smooth muscle cell calcium channels. RESULTS: After treatment, blood pressure of the Shijueming (Concha Haliotidis) group lowered but not significantly (P>0.05). Blood pressure of the nifedipine group lowered significantly (P<0.05). Blood pressure of the distilled water group remained high. The concentration of serum calcium in the Shijueming (Concha Haliotidis) and the distilled water groups lowered (P<0.05). Expression of CaL-α1C mRNA in the nifedipine group decreased compared with the distilled water group (P<0.01). There was the decreasing trend in the Shijueming (Concha Haliotidis) group, but it was not statistically significant. Shijueming (Concha Haliotidis) also had effects on the expression of PMCA1 mRNA but with- out statistical significance. However, there was a significant decreasing effect on vascular smooth muscle cell I Ca-L flow. CONCLUSION: This study indicated that Shijueming (Concha Haliotidis) could increase serum calcium and decrease blood pressure. It may work by influencing calcium channels, expression of PMCA1 mRNA, and regulating ion calcium channels and calcium-ATPase. | Chao Chen Changlin Zhao Xuejun Wang Weili Li Xiaoyin Chen | 2013 | Journal of Traditional Chinese Medicine2013，33，3： | 4 |
| 4 | Zooplankton composition and distribution in the Lembeh Strait of North Sulawesi, Indonesia显示文摘Based on oceanographic survey data in June 2012 in the Lembeh Strait, the zooplankton ecological characteristics such as species composition, individual abundance, dominant species and distribution were analyzed. The results showed that 183 species(including 4 sp.) had been recognized, most of them belonged to copepoda.Cnidaria followed with 43 species(including 1 sp.) were identified. The average abundance of zooplankton was(150.47±58.91) ind./m^3. As to the horizontal distribution, the abundance of the zooplankton was higher in the southern waters than in the northern waters. The dominant species in the study area were Lensia subtiloides,Sagitta enflata, Lucifer intermedius, Oikopleura rufescens, Diphyes chamissoni, Creseis acicula, Subeucalanus subcrassus, Temora discaudata, Aglaura hemistoma, Doliolum denticulatum, Canthocalanus pauper, Oikopleura longicauda and Nanomia bijuga. Zooplankton biodiversity indexes were higher in study area than previous study in the other regions. The findings from this study provide important baseline information for future research and monitoring programs. | WANG Yanguo CHEN Xiaoyin XING Bingpeng SUN Rouxin FITRIA Nurul XIANG Peng WANG Chunguang LIN Mao | 2018 | Acta Oceanologica Sinica2018，37，12： | 3 |
| 5 | MAP3K2 augments Th1 cell differentiation via IL-18 to promote T cell-mediated colitis显示文摘T cell-mediated immunity in the intestine is stringently controlled to ensure proper immunity against pathogenic microbes and to prevent autoimmunity,a known cause of inflammatory bowel disease.However,precisely how T cells regulate intestine immunity remains to be fully understood.In this study,we found that mitogen-activated protein kinase kinase kinase 2(MAP3K2)is required for the CD4^(+)T cell-mediated inflammation in the intestine.Using a T cell transfer colitis model,we found that MAP3K2-deficient naïve CD4^(+)T cells had a dramatically reduced ability to induce colitis compared to wild type T cells.In addition,significantly fewer IFN-γ-but more IL-17A-producing CD4^(+)T cells in the intestines of mice receiving MAP3K2-deficient T cells than in those from mice receiving wild type T cells was observed.Interestingly,under well-defined in vitro differentiation conditions,MAP3K2-deficient naïve T cells were not impaired in their ability to differentiate into Th1,Th17 and Treg.Furthermore,the MAP3K2-regulated colitis severity was mediated by Th1 but not Th17 cells in the intestine.At the molecular level,we showed that MAP3K2-mediated Th1 cell differentiation in the intestine was regulated by IL-18 and required specific JNK activation.Together,our study reveals a novel regulatory role of MAP3K2 in intestinal T cell immunity via the IL-18-MAP3K2-JNK axis and may provide a novel target for intervention in T cell-mediated colitis. | Ningbo Wu Dongping Chen Hongxiang Sun Jianmei Tan Yao Zhang Tianyu Zhang Yuheng Han Hongzhi Liu Xinxing Ouyang Xiao-Dong Yang Xiaoyin Niu Jie Zhong Zhengting Wang Bing Su | 2021 | Science China(Life Sciences)2021，64，3： | 3 |
| 6 | A high-Tc dc-SQUID-based single-channel MCG and its performance显示文摘A single-channel high-Tc dc-SQUID magnetometer and gradiometer have been developed to record the magnetic field component perpendicular to the human chest generated by heart-beat. Magnetocardiogram (MCG) measurements have been carried out inside a magnetically shielded room. By sequentially adjusting a non-magnetic patient table with 5 cm pitch in X and Y directions, the field signals on a rectangle grid 5×5 over the chest area were registered in real time trace point by point with a typical dwell time over 30 cardiocycles each. Utilizing standard electrocardiogram (ECG) recordings as timing reference measured simultaneously with the MCG signals, the MCG data were then averaged and combined to form magnetic field patterns every 10 ms or so. Both the current dipole, which is parallel to MCG measuring plane and produces the vertical magnetic field, and its depth were determined as a function of time in a standard way. We have compared the MCG of healthy hearts with that of a heart with right bundle | WANG Huiwu DING Hongsheng ZHANG Lihua HUANG Xuguang CHEN Weichang WANG Ziqiang FENG Ji LIU Yiping ZHAO Shiping REN Yufeng YU Hongwei XU Fengzhi WANG Xiaoyin CHEN Genghua YANG Qiansheng | 2002 | Chinese Science Bulletin2002，47，22： | 2 |
| 7 | Single-atom catalysts for metal-sulfur batteries:Current progress and future perspectives显示文摘Metal-sulfur batteries are recognized as a promising candidate for next generation electrochemical energy storage systems owing to their high theoretical energy density,low cost and environmental friendliness.However,sluggish redox kinetics of sulfur species and the shuttle effect lead to large polarization and severe capacity decay.Numerous approaches from physical barrier,chemical adsorption strategies to electrocatalysts have been tried to solve these issues and pushed the rate and cycle performance of sulfur electrodes to higher levels.Most recently,single-atom catalysts(SACs)with high catalytic efficiency have been introduced into metal-sulfur systems to achieve fast redox kinetics of sulfur conversion.In this review,we systematically summarize the current progress on SACs for sulfur electrodes from aspects of synthesis,characterization and electrochemical performance.Challenges and potential solutions for designing SACs for high-performance sulfur electrodes are discussed. | Ru Xiao Ke Chen Xiaoyin Zhang Zhenzhen Yang Guangjian Hu Zhenhua Sun Hui-Ming Cheng Feng Li | 2021 | Journal of Energy Chemistry2021，30，3： | 2 |
| 8 | An Empirical Study on the Contribution of Foreign Trade to the Economic Growth of Jiangxi Province, China显示文摘 | Xiaoyin Wang Zhongwen Chen Yuhong Li | 2010 | iBusiness2010，，02： | 1 |
| 9 | Comparison of effect of La-modification on the thermostabilities of alumina and alumina-support Pd catalysts prepared from different alumina sources显示文摘 | YANG Zhuxian CHEN Xiaoyin NIU Guoxin | 2001 | Applied Catalysis B:Environmental2001，29，： | 1 |
| 10 | Comparison of effect of La-modifcation on the thermostabilities of alumina and alumina-supported Pd catalysts prepared from different alumina sources 显示文摘 | YANG Zhuxian CHEN Xiaoyin NIU Guoxin | 2001 | Applied Catalysis B: Environmental2001，，5： | 1 |
| 11 | 显示文摘 | Hong Xiaoyin Chen Qidao Chen Ming | 2002 | Pro- gress in Organic Coatings2002，45，： | 1 |
| 12 | Spontaneous rupture of hepatocellular carcinoma trans-arterial embolization or hepatectomy?显示文摘Spontaneous rupture and hemorrhage of hepatocellular carcinoma(HCC)is one of the serious complications leading to death in patients with primary liver cancer.Approximately 9-10%of those patients with liver cancer die of from spontaneous rupture and hemorrhage,which is often accompanied by abdominal metastasis and seriously affects their prognosis(1). | Qingbo Feng Xiaoyin Liu Xuping Feng Chuwen Chen Jiaxin Li Yong Zeng | 2022 | Hepatobiliary Surgery and Nutrition2022，11，6： | 1 |
| 13 | Enhanced mechanical properties and morphological characterizations of poly(vinyl alcohol)–carbon nanotube composite films显示文摘 | Wei Chen Xiaoming Tao Pu Xue Xiaoyin Cheng | 2005 | Applied Surface Science2005，，5： | 1 |
| 14 | Mechanism and operation parameters of a plasma-driven micro-particle accelerator显示文摘There is a large amount of micro debris ranging between millimeters and micrometers in space, which has significant influence on the reliability and life of spacecrafts through long-duration integrated impacts and has to be considered in designing a vehicle's suitability to the space environment. In order to simulate the micro-impacts on exposed materials, a plasma-driven micro-particle accelerator was developed. The major processes, including the acceleration, compression and ejection of plasmas, were modeled. By comparing the theoretical simulations with the experimental results, the acceleration mechanism was clarified. Moreover, through a series of experiments, the optimum operation range was investigated, and the acceleration ability was primarily determined. | HUANG JianGuo HAN JianWei LI HongWei CAI MingHui LI xiaoYin ZHANG ZhenLong CHEN ZhaoFeng WANG Long YANG XuanZong FENG ChunHua | 2009 | Chinese Science Bulletin2009，54，4： | 1 |
| 15 | Comparison of effect of La-modification on thethemostabilities of alumina and alumina-support Pdcatalysts prepared from different alumina sources显示文摘 | YANG Zhaxian CHEN Xiaoyin NIU Guoxin | 2001 | Applied Catalysis B:Enviromental2001，29，： | 1 |
| 16 | Reversal of Multidrug Resistance of Adriamycin-resistant Gastric Adenocarcinoma Cells Through the Up-regulation of DARPP-32显示文摘 | Liu Hong Yunping Zhao Jin Wang Ying Han Wei Guo Haifeng Jin Huihong Zhai Feihu Bai Xiaoyin Zhang Taidong Qiao Zhen Chen Daiming Fan | 2008 | Digestive Diseases and Sciences2008，，1： | 1 |
| 17 | IL-21 regulates Th17 cells in rheumatoid arthritis显示文摘 | Xiaoyin Niu Dongyi He Xin Zhang Tao Yue Ningli Li Jingwu Z. Zhang Chen Dong Guangjie Chen | 2010 | Human Immunology2010，，4： | 1 |
| 18 | Enhanced mechanical properties and morphological characterizations of poly(vinyl alcohol) carbon nanotube composite films 显示文摘 | Chen Wei Tao Xiaoming Xue Pu Cheng Xiaoyin | 2005 | Applied Surface Science2005，252，： | 1 |
| 19 | 显示文摘 | Chang Huazhen Li Junhua Chen Xiaoyin | 2012 | Catalysis Communications2012，27，： | 1 |
| 20 | Comparison of effect of La-modification on the thermostabilities of alumina and alumina-supported Pd catalysts prepared from different alumina sources 显示文摘 | Chen Xiaoyin Niu Guoxin | 2001 | Applied Catalysis B: Environmental2001，185，： | 1 |
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