|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effects of Shuanghuanglian oral liquids on patients with COVID-19:a randomized,open-label,parallel-controlled,multicenter clinical trial显示文摘We conducted a randomized,open-label,parallel-controlled,multicenter trial on the use of Shuanghuanglian(SHL),a traditional Chinese patent medicine,in treating cases of COVID-19.A total of 176 patients received SHL by three doses(56 in low dose,61 in middle dose,and 59 in high dose)in addition to standard care.The control group was composed of 59 patients who received standard therapy alone.Treatment with SHL was not associated with a difference from standard care in the time to disease recovery.Patients with 14-day SHL treatment had significantly higher rate in negative conversion of SARS-CoV-2 in nucleic acid swab tests than the patients from the control group(93.4%vs.73.9%,P=0.006).Analysis of chest computed tomography images showed that treatment with high-dose SHL significantly promoted absorption of inflammatory focus of pneumonia,which was evaluated by density reduction of inflammatory focus from baseline,at day 7(mean difference(95%CI),−46.39(−86.83 to−5.94)HU;P=0.025)and day 14(mean difference(95%CI),−74.21(−133.35 to−15.08)HU;P=0.014).No serious adverse events occurred in the SHL groups.This study illustrated that SHL in combination with standard care was safe and partially effective for the treatment of COVID-19. | Li Ni Zheng Wen Xiaowen Hu Wei Tang Haisheng Wang Ling Zhou Lujin Wu Hong Wang Chang Xu Xizhen Xu Zhichao Xiao Zongzhe Li Chene Li Yujian Liu Jialin Duan Chen Chen Dan Li Runhua Zhang Jinliang Li Yongxiang Yi Wei Huang Yanyan Chen Jianping Zhao Jianping Zuo Jianping Weng Hualiang Jiang Dao Wen Wang | 2021 | Frontiers of Medicine2021，15，5： | 7 |
| 2 | Review of Femtosecond-Laser-Inscribed Fiber Bragg Gratings:Fabrication Technologies and Sensing Applications显示文摘Fiber Bragg grating(FBG)is the most widely used optical fiber sensor due to its compact size,high sensitivity,and easiness for multiplexing.Conventional FBGs fabricated by using an ultraviolet(UV)laser phase-mask method require the sensitization of the optical fiber and could not be used at high temperatures.Recently,the fabrication of FBGs by using a femtosecond laser has attracted extensive interests due to its excellent flexibility in creating FBGs array or special FBGs with complex spectra.The femtosecond laser could also be used for inscribing various FBGs on almost all fiber types,even fibers without any photosensitivity.Such femtosecond-laser-induced FBGs exhibit excellent thermal stability,which is suitable for sensing in harsh environment.In this review,we present the historical developments and recent advances in the fabrication technologies and sensing applications of femtosecond-laser-inscribed FBGs.Firstly,the mechanism of femtosecond-laser-induced material modification is introduced.And then,three different fabrication tech no logies,i.e.,femtosecond laser phase mask technology,femtosecond laser holographic interferometry,and femtosecond laser direct writing technology,are discussed.Finally,the advances in high-temperature sensing applications and vector bending sensing applications of various femtosecond-laser-inscribed FBGs are summarized.Such femtosecond-laser-inscribed FBGs are promising in many industrial areas,such as aerospace vehicles,nuclear plants,oil and gas explorations,and advanced robotics in harsh environments. | Jun HE Baijie XU Xizhen XU Changrui LIAO Yiping WANG | 2021 | Photonic Sensors2021，11，2： | 6 |
| 3 | Nitrate δ^(15)N and δ^(18)O evidence for active biological transformation in the Changjiang Estuary and the adjacent East China Sea显示文摘The Changjiang Estuary has been considered as one of the most polluted estuaries in the world due to high nitrate (NO-3) input, especially in spring and summer. In this study, δ15N and δ18O of NO-3 , along with other chemical parameters in this area, were measured in spring to evaluate NO-3 biogeochemical processes. A simple two end-members mixing model was used to examine the relative contribution of the Changjiang River Diluted Water and marine water to NO-3 sources in the Changjiang Estuary and the adjacent East China Sea. The isotopic signals show that NO-3 behaved relatively and conservatively in Transect F and Transect P where assimilation was weak possibly due to vertical mixing, while active assimilation and weak nitrification occurred in Transect D. Spatial difference in assimilation was indicated by the~1:1 enrichment of δ15N and δ18O in the three transects, while spatial difference in nitrification was reflected by deviations of δ15 N and δ18O from assimilation line. Our results suggest that the input of the Changjiang River Diluted Water promoted NO-3 assimilation possibly by stratifying the water column which favored the phytoplankton growth. | CHEN Fajin CHEN Jianfang JIA Guodong JIN Haiyan XU Jie YANG Zhi ZHUANG Yanpei LIU Xizhen ZHANG Haisheng | 2013 | Acta Oceanologica Sinica2013，32，4： | 4 |
| 4 | Single-mode helical Bragg grating waveguide created in a multimode coreless fiber by femtosecond laser direct writing显示文摘We demonstrate the fabrication of single-mode helical Bragg grating waveguides(HBGWs)in a multimode core-less fiber by using a femtosecond laser direct writing technique.This approach provides a single-step method for creating Bragg grating waveguides.Specifically,the unique helical structure in such an HBGW serves as a depressed cladding waveguide and also generates strong Bragg resonance due to its periodicity.Effects of pulse energy,helical diameter,and helical pitch used for fabricating HBGWs were studied,and a single-mode HBGW with a narrow bandwidth of 0.43 nm and a Bragg wavelength of 1546.50 nm was achieved by using appropriate parameters,including a diameter of 10μm and a helical pitch of 1.07μm.The measured cross-sectional refractive index profile indicates that a depressed cladding waveguide has been created in this single-mode HBGW.Moreover,five single-mode HBGWs with various Bragg wavelengths were successfully fabricated by controlling the helical pitch,and this technique could be used for achieving a wavelength-division-multiplexed HBGW array.Then,the temperature and strain responses of the fabricated single-mode HBGW were tested,exhibiting a temperature sensitivity of 11.65 pm/℃ and a strain sensitivity of 1.29 pm/με,respectively.In addition,the thermal stability of the single-mode HBGW was also studied by annealing at a high temperature of 700℃ for 15 h.The degeneration of the single-mode waveguide into a multimode waveguide was observed during the isothermal annealing process,and the peak reflection and the Bragg wavelength of the fundamental mode exhibited a decrease of∼7 dB and a“blue”shift of 0.36 nm.Hence,such a femtosecond laser directly written single-mode HBGW could be used in many applications,such as sapphire fiber sensors,photonic integrated circuits,and monolithic waveguide lasers. | JUN HE JIA HE XIZHEN XU BIN DU BAIJIE XU CHANGRUI LIAO ZHIYONG BAI YIPING WANG | 2021 | Photonics Research2021，9，10： | 4 |
| 5 | Design and immunogenicity assessment of HIV-1 virus-like particles as a candidate vaccine显示文摘The rapid growth of the global HIV/AIDS epidemic makes it a high priority to develop an effective vaccine.Since a live attenuated or inactivated HIV vaccine is not likely to be approved for clinical application due to safety concerns,HIV virus like particles(VLPs) offer an attractive alternative because they are considered safer since they lack viral genome.We got a stable eukaryotic cell line by G418 resistance selection,engineered to express the HIV-1 structure protein Gag and Env efficiently and stably.We confirmed the presence of Gag and Env proteins in the cell culture supernatant and that they could self-assemble into VLPs.These VLPs were found to be able to elicit specific humoral and cellular immune response after immunization without any adjuvant. | ZHANG XiZhen WANG XiaoDan ZHAO DongHai MENG XiangYu ZHAO XingHong YU XiangHui KONG Wei | 2011 | Science China(Life Sciences)2011，54，11： | 4 |
| 6 | EETs and CYP2J2 inhibit TNF-α-induced apoptosis in pulmonary arteryendothelial cells and TGF-β1-induced migration in pulmonary artery smooth musclecells显示文摘 | Wenjing Feng Xizhen Xu Gang Zhao Geng Li Tiantian Liu Junjie Zhao Ruolan Dong Dao Wang Ling Tu | 2013 | International Journal of Molecular Medicine2013，，3： | 2 |
| 7 | Identification of a novel hydrolase encoded by hy-1 from Bacillus amyloliquefaciens for bioremediation of carbendazim contaminated soil and food显示文摘Carbendazim(MBC)is an effective antifungal and antibacterial pesticide in agricultural applications.However,the MBC-contaminated soil and food are difficult to be restored.In this work,a novel MBC-hydrolase HY-1 encoded by gene hy-1 from an isolated MBC-degrading bacteria Bacillus amyloliquefaciens has been screened and identified.The 858 bp hydrolase gene was expressed in E.coli BL21 and the 32 kDa hydrolase HY-1 was purified.The purified HY-1 was able to catalyze MBC into 2-aminobenzimidazole(2-AB)without the need for any cofactors.Then bioremediation experiment was conducted and both the strain Car4 and cell crude extract of E.coli(pET-hy1)accelerated MBC degradation in soil.Moreover,purified HY-1 was available in removing MBC residue on the surface of cucumber.This work explored the possibility of microbial and enzymatic bioremediation on MBC-contaminated soil and food,provide a new way for bioremediation of pesticide contaminations. | Ying Li Miaomiao Chi Xizhen Ge | 2019 | International Journal of Agricultural and Biological Engineering2019，12，2： | 2 |
| 8 | Investigation on Thermal Melting and Denaturation of DNA molecules based upon Non-equilibrium Transport Theory显示文摘 | YANG Huijie ZHUO Yizhong WU Xizhen | 1994 | Journal of Physics1994，27，： | 1 |
| 9 | Spatial Distribution Characteristics of Intercepted Rainwater on Rock Desertified Shrub Slopes in the Northern Guangdong Region显示文摘 | XinghuWei Xizhen Xu Li Lei | 2013 | 地球科学期刊(中英文版)2013，3，2： | 1 |
| 10 | Adsorption of acid dyes from aqueous solutions by the ethylenediamine-modified magnetic chitosan nanoparticles显示文摘 | Limin Zhou Jieyun Jin Zhirong Liu Xizhen Liang Chao Shang | 2010 | Journal of Hazardous Materials2010，，2： | 1 |
| 11 | Enhanced sodium storage performance in flexible free- standing multichannel carbon nanofibers with enlarged interlayer spacing显示文摘一个灵活、自立的多信道的碳 nanofiber (MCNF ) 电影电极通过 electrospinning 和碳化被制作。在在真空的 MCNF 的高温度的处理以后,获得的纤维(MCNFs-V ) 有 graphene 表(0.398 nm ) 和一个极端低的特定的表面区域的扩大夹层间距(15.3 m 2/g) 。当为钠离子电池用作阳极时, MCNFs-V 证明在 0.1 V 下面的一个分泌物高原,和钠在 sodiation 过程期间被设置进叠的 graphene 表层。MCNFs-V 在 100 个周期和优秀长期的骑车稳定性以后在 0.1 A/g 的当前的密度展出了 222 mAh/g 的一个可逆、高的特定的能力,它比 MCNF 的优异。改进的钠存储表演为钠置闰与 graphene 表的扩大夹层间距被归因于 MCNFs-V 的唯一的微观结构。MCNFs-V 电极为商业钠离子电池作为阳极材料保持大诺言。 | Beibei Yuan Linchao Zeng Xizhen Sun Yan Yu Qingsong Wang | 2018 | Nano Research2018，11，4： | 1 |
| 12 | Adsorption of platinum(Ⅳ) and palladium(Ⅱ) from aqueous solution by magnetic cross-linking chitosan nanoparticles modified with ethylenediamine显示文摘 | Limin Zhou Jianping Xu Xizhen Liang Zhirong Liu | 2010 | Journal of Hazardous Materials2010，182，13： | 1 |
| 13 | Effects of Bi^(3+) on down-/up-conversion luminescence,temperature sensing and optical transition properties of Bi^(3+)/Er^(3+)co-doped YNbO_(4) phosphors显示文摘A series of YNbO_(4):Bi^(3+) and YNbO_(4):Bi^(3+)/Er^(3+) phosphors were prepared by a conventional high temperature solid-state reaction method.The results of XRD and Rietveld refinement confirm that monoclinic phase YNbO_(4)samples are achieved.The down-/up-conversion luminescence of Er^(3+) ions was investigated under the excitation of ultraviolet light(327 nm)and near infrared light(980 nm).Under 327 nm excitation,broad visible emission band from Bi^(3+) ions and characteristic green emission peaks from Er^(3+) ions are simultaneously observed,while only strong green emissions from Er^(3+) ions are detected upon excitation of 980 nm.Remarkable emission enhancement is observed in down-/up-conversion luminescence processes by introducing Bi^(3+) ions into Er^(3+)-doped YNbO_(4)phosphors.Pumped current versus up-conversion emission intensity study shows that two-photon processes are responsible for both the green and the red up-conversion emissions of Er^(3+)ion.Through the study of the temperature sensing property of Er^(3+) ion,it is affirmed that the temperature sensitivity is sensitive to the doping concentration of Bi^(3+) ions.By comparing the experimental values of the radiative transition rate ratio of the two green emission levels of Er^(3+) ions and the theoretical values calculated by Judd-Ofelt(J-O)theory,it is concluded that the temperature sensing property of Er^(3+) ions is greatly affected by the energy level splitting. | Xin Wang Xiangping Li Hongquan Yu Sai Xu Jiashi Sun Lihong Cheng Xizhen Zhang Jinsu Zhang Yongze Cao Baojiu Chen | 2022 | Journal of Rare Earths2022，40，3： | 1 |
| 14 | Transcriptome analysis of Chlamydomonas reinhardtii during the process of lipid accumulation显示文摘 | Lv(Lyu) Hexin Qu Ge Qi Xizhen | 2013 | Genomics2013，101，4： | 1 |
| 15 | New invariant of DNA sequence based on 3DD-eurves and its application on phylog- eny 显示文摘 | ZHANG XIZHEN LUO JIAWEI YANG LI | 2007 | Journal of Computational Chemistry2007，28，14： | 1 |
| 16 | Correlations between the North China Craton and the Indian Shield:Constraints from regional metallogeny显示文摘The correlation between the North China Craton(NCC) and the Indian Shield(IND) has been a hot topic in recent years,On the basis of ore deposit databases,the NCC and IND have shown broad similarity in metallogenesis from the middle Archaean to the Mesoproterozoic,The two blocks both have three major metallogenic systems:(1) the Archaean BIF metallogenic system;(2) the Paleoproterozoic Cu-Pb-Zn metallogenic system;and(3) the Mesoproterozoic Fe-Pb-Zn system,In the north margin of the NCC and the west margin of the IND,the Archaean BIF-Au-Cu-Pb-Zn deposits had the same petrogenesis and host rocks,the Paleoproterozoic Cu-Pb-Zn deposits were controlled by active belts,and the Mesoproterozoic Fe-Pb-Zn deposits were mainly related to multi-stage rifting,Matching regional mineralization patterns and geological features has established the continental assembly referred to as 'NCWI',an acronym for the north margin of the NCC(NC) and the west margin of the IND(WI) during the middle Archaean to the Mesoproterozoic,In this assembly,the available geological and metallogenic data from the Eastern Block and active belts of NC fit those from the Dharwar craton and the Aravalli-DelhiVindhyan belt of WI,respectively,Moreover,the depositional model and environment of Paleoproterozoic metasedimentary manganese deposits in NCWI implied that the assembly may be located at low latitudes,where the conditions were favorable for dissolving ice and precipitating manganese deposits, | Caifeng Li Dongyue Chen Jianping Chen Xizhen Chen Xingchen Yang M.A.Aboelnour | 2015 | Geoscience Frontiers2015，6，6： | 1 |
| 17 | Variational path-integral approach to a nonlinear open system 显示文摘 | ZhuoYizhong Wu Xizhen | 1995 | Phys Rev1995，52，： | 1 |
| 18 | Identification method of IGBT limiting current and limiting power loss显示文摘 | Zhou Wenjun Liu Xizhen Li Zhengqin | 2002 | Journal of Tianjin University2002，35，2： | 1 |
| 19 | A revaluation of the rankinite phase in the Ca0-SiOz system 显示文摘 | Hillert M Sudman B Xizhen W | 1991 | Calphad1991，1，15： | 1 |
| 20 | Dynamic realization of transport phenomenon in finite system显示文摘 | Shiwei Yan Fumihikl Sakata Yizhong zhuo Xizhen Wu | 2001 | Physical Review E2001，63，02： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员