|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Changes of net primary productivity in China during recent 11 years detected using an ecological model driven by MODIS data显示文摘网主要生产率(NPP ) 是陆上的碳周期的一个重要部件。精确地在中国印射 NPP 的空间时间的变化为全球碳骑车是关键的学习。在这研究,基于过程的北方的生态系统生产率模拟器(BEPS ) 被采用从 2000 ~ 2010 为时期在中国的生态系统学习 NPP 的变化。BEPS 模型首先用在在不同区域测量的典型流动地点和森林 NPP 测量的粗野主要生产率(GPP ) 被验证。然后,它与叶区域索引( LAI )被驾驶从中等分辨率成像分光辐射函数( MODIS )反射和陆地盖子产品和气象学的数据的 inversed 在 753 个国家基本气象学的车站从观察插入内推从1月1日在每日的时间步和 500 m 的空间分辨率模仿 NPP , 2000 到2010年12月31日。确认证明 BEPS 能在中国的不同区域捕获基于塔的 GPP 的季节的变化和森林 NPP 的空间可变性。年度 NPP 的估计的国家总数从 2.63 变化了到 2.84Pg C 獥吗? | Yibo LIU Weimin JU Honglin HE Shaoqiang WANG Rui SUN Yuandong ZHANG | 2013 | Frontiers of Earth Science2013，7，1： | 30 |
| 2 | Genome-wide Association Analyses Reveal the Genetic Basis of Stigma Exsertion in Rice显示文摘耻辱 exsertion,交配系统的米饭的一个关键决定因素,极大地在米饭贡献杂种优势的申请。尽管与耻辱 exsertion 联系的一些量的特点 loci 是印射或克隆的罚款,内在的基因建筑学仍然保持不清楚。我们用在 Oryza sativa 的 533 多样的就职描绘的 650 万 SNP 在耻辱 exsertion 和相关花的特点上执行了染色体宽的协会研究。我们识别了显著地与耻辱 exsertion 和相关特点,其三与三主要谷物尺寸基因 GS3, GW5,和 GW2 co 局部性被联系的 23 genomic loci。进一步的分析显示这三基因由控制小穗状花小穗和耻辱的尺寸和形状影响了耻辱 exsertion。GS3 和 GW5 的联合大部分定义耻辱 exsertion 和相关特点的层次。这二基因的选择在 O 的 subpopulations 之中导致了花的特点的特定的分布。sativa。低耻辱 exsertion 联合 gw5GS3 在栽培米饭变化的一半存在;因此,介绍 GW5gs3 联合进男无菌的线具有为改进混合米饭的种子生产的高潜力。 | Hao Zhou Pingbo Li WeiboXie Saddam Hussain Yibo Li Duo Xia Hu Zhao Shengyuan Sun Junxiao Chen Hong Ye Jun Hou Da Zhao Guanjun Gao Qinglu Zhang Gongwei Wang Xingming Lian Jinghua Xiao Sibin Yu Xianghua Li Yuqing He | 2017 | Molecular Plant2017，10，4： | 15 |
| 3 | TOPOLOGY OPTIMIZATION OF TRUSS STRUCTURES WITH SYSTEMATIC RELIABILITY CONSTRAINTS UNDER MULTIPLE LOADING CASES显示文摘In this paper,a mathematical model for topology optimization of truss structures withconstraints of displacement and system reliability under multiple loading cases is constructed.In orderto avoid the difficulty of computing the structure’s system reliability,a solving approach is presented inwhich the failure probability of system is divided into the sum of all bars’ failure probability by meansof reliability distribution.In addition,by drawing into the reliability safety factor and the fundamen-tal relationship in structural mechanics,all probability constraints of displacement and stress are equiv-alently displayed as conventional form and linear function of the design variables.The optimizationproblem with multiple constraints is treated by the compact constraint tactics and is solved by the im-proved simplex method.The examples show that the approach proposed in this paper is feasible and ef-ficient. | Chen Jianjun Cao Yibo Sun Huaian | 1999 | Acta Mechanica Solida Sinica1999，12，2： | 8 |
| 4 | The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability. | Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding | 2022 | Molecular Plant2022，15，5： | 6 |
| 5 | Can climate change influence agricultural GTFP in arid and semi-arid regions of Northwest China?显示文摘There are eight provinces and autonomous regions(Gansu Province,Ningxia Hui Autonomous Region,Xinjiang Uygur Autonomous Region,Inner Mongolia Autonomous Region,Tibet Autonomous Region,Qinghai Province,Shanxi Province,and Shaanxi Province)in Northwest China,most areas of which are located in arid and semi-arid regions(northwest of the 400 mm precipitation line),accounting for 58.74%of the country's land area and sustaining approximately 7.84×10^6 people.Because of drought conditions and fragile ecology,these regions cannot develop agriculture at the expense of the environment.Given the challenges of global warming,the green total factor productivity(GTFP),taking CO2 emissions as an undesirable output,is an effective index for measuring the sustainability of agricultural development.Agricultural GTFP can be influenced by both internal production factors(labor force,machinery,land,agricultural plastic film,diesel,pesticide,and fertilizer)and external climate factors(temperature,precipitation,and sunshine duration).In this study,we used the Super-slacks-based measure(Super-SBM)model to measure agricultural GTFP during the period 2000-2016 at the regional level.Our results show that the average agricultural GTFP of most provinces and autonomous regions in arid and semi-arid regions underwent a fluctuating increase during the study period(2000-2016),and the fluctuation was caused by the production factors(input and output factors).To improve agricultural GTFP,Shaanxi,Shanxi,and Gansu should reduce agricultural labor force input;Shaanxi,Inner Mongolia,Gansu,and Shanxi should decrease machinery input;Shaanxi,Inner Mongolia,Xinjiang,and Shanxi should reduce fertilizer input;Shaanxi,Xinjiang,Gansu,and Ningxia should reduce diesel input;Xinjiang and Gansu should decrease plastic film input;and Gansu,Shanxi,and Inner Mongolia should cut pesticide input.Desirable output agricultural earnings should be increased in Qinghai and Tibet,and undesirable output(CO2 emissions)should be reduced in Inner Mongolia,Xinjiang,Gansu,and Shaanxi.Agricultural GTFP is influenced not only by internal production factors but also by external climate factors.To determine the influence of climate factors on GTFP in these provinces and autonomous regions,we used a Geographical Detector(Geodetector)model to analyze the influence of climate factors(temperature,precipitation,and sunshine duration)and identify the relationships between different climate factors and GTFP.We found that temperature played a significant role in the spatial heterogeneity of GTFP among provinces and autonomous regions in arid and semi-arid regions.For Xinjiang,Inner Mongolia,and Tibet,a suitable average annual temperature would be in the range of 7℃-9℃;for Gansu,Shanxi,and Ningxia,it would be 11℃-13℃;and for Shaanxi,it would be 15℃-17℃.Stable climatic conditions and more efficient production are prerequisites for the development of sustainable agriculture.Hence,in the agricultural production process,reducing the redundancy of input factors is the best way to reduce CO2 emissions and to maintain temperatures,thereby improving the agricultural GTFP.The significance of this study is that it explores the impact of both internal production factors and external climatic factors on the development of sustainable agriculture in arid and semi-arid regions,identifying an effective way forward for the arid and semi-arid regions of Northwest China. | FENG Jian ZHAO Lingdi ZHANG Yibo SUN Lingxiao YU Xiang YU Yang | 2020 | Journal of Arid Land2020，12，5： | 6 |
| 6 | A Modular DC/DC Photovoltic Generation System for HVDC Grid Connection显示文摘A modular DC/DC conversion system with distributed MPPT and centralized step-up converter for photovoltaic energy integrated into HVDC grids is proposed in this paper.The conversion system consists of two power stages,with MPPT converter as the first stage and a step-up converter as the second stage.Both stages are modular structures.For the distributed MPPT stage,interleaved boost topology is utilized to effectively reduce the input and output ripples without adding extra components.For the centralized step-up stage,narrow-switching-frequency-variation LLC topology is employed,with the modules being configured as input-parallel-output-series structure.Full-range soft-switching property is achieved in the LLC stage to minimize switching losses.Theoretical analysis is carried out for the system voltage gain and design principles.Simulation and experimental results of a 3kW prototype system are presented to verify the theoretical analysis of the proposed system. | Guoen Cao Kai Sun Siyue Jiang Shilei Lu Yibo Wang | 2018 | Chinese Journal of Electrical Engineering2018，4，2： | 5 |
| 7 | SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer显示文摘 | Andreas I Papadakis Chong Sun Theo A Knijnenburg Yibo Xue Wipawadee Gremrum Michael Holzel Wouter Nijkamp Lodewyk FA Wessels Roderick L Beijersbergen Rene Bernards Sidong Huang | 2015 | Cell Research2015，25，4： | 4 |
| 8 | Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis显示文摘Depression is a serious public-health issue.Recent reports have suggested higher susceptibility to viral infections in depressive patients.However,how depression affects antiviral innate immune signaling remains unknown.Here,we revealed a reduction in expression of Abelson helper integration site 1(AHI1)in the peripheral blood mononuclear cells(PBMCs)and macrophages from the patients with major depressive disorder(MDD),which leads to attenuated antiviral immune response.We found that depression-related arginine vasopressin(AVP)induces reduction of AHI1 in macrophages.Further studies demonstrated that AHI1 is a critical stabilizer of basal type-I-interferon(IFN-I)signaling.Mechanistically,AHI1 recruits OTUD1 to deubiquitinate and stabilize Tyk2,while AHI1 reduction downregulates Tyk2 and IFN-I signaling activity in macrophages from both MDD patients and depression model mice.Interestingly,we identified a clinical analgesic meptazinol that effectively stimulates AHI1 expression,thus enhancing IFN-I antiviral defense in depression model mice.Our study promotes the understanding of the signaling mechanisms of depression-mediated antiviral immune dysfunction,and reveals meptazinol as an enhancer of antiviral innate immunity in depressive patients. | Hong-Guang Zhang Bin Wang Yong Yang Xuan Liu Junjie Wang Ning Xin Shifeng Li Ying Miao Qiuyu Wu Tingting Guo Yukang Yuan Yibo Zuo Xiangjie Chen Tengfei Ren Chunsheng Dong Jun Wang Hang Ruan Miao Sun Xingshun Xu Hui Zheng | 2022 | Cell Research2022，32，10： | 3 |
| 9 | Diffuse Intrinsic Pontine Gliomas Exhibit Cell Biological and Molecular Signatures of Fetal Hindbrain-Derived Neural Progenitor Cells显示文摘Diffuse intrinsic pontine glioma(DIPG) is the main cause of brain tumor-related death among children.Until now, there is still a lack of effective therapy with prolonged overall survival for this disease. A typical strategy for preclinical cancer research is to find out the molecular differences between tumor tissue and para-tumor normal tissue, in order to identify potential therapeutic targets. Unfortunately, it is impossible to obtain normal tissue for DIPG because of the vital functions of the pons.Here we report the human fetal hindbrain-derived neural progenitor cells(pontine progenitor cells, PPCs) as normal control cells for DIPG. The PPCs not only harbored similar cell biological and molecular signatures as DIPG glioma stem cells, but also had the potential to be immortalized by the DIPG-specific mutation H3 K27 M in vitro. These findings provide researchers with a candidate normal control and a potential medicine carrier for preclinical research on DIPG. | Yu Sun Cheng Xu Changcun Pan Xin Chen Yibo Geng Yuliang Wu Peng Zhang Wenhao Wu Yu Wang Deling Li Zhen Wu Junting Zhang Qiaoran Xi Liwei Zhang | 2019 | Neuroscience Bulletin2019，35，2： | 2 |
| 10 | Imaging bacteriorhodopsin-like molecules of claret-membranes from Tibet halobacteria xz515 by atomic force microscope显示文摘Halobacteria H.sp.xz 515 was isolated from a salt lake in Tibet. Although proton release-and-uptake across claret membrane is in reverse order compared to bacteri-orhodopsin in purple membrane from Halobacterium Sali-narum, and its efficiency of proton pump is much lower, AFM image shows that the molecules are still arranged in a two-dimensional hexagonal lattice of trimers. Primary structure of C- to G-helix of the archaerhodopsin shows that it has only 56% homology with bacteriorhodopsin. But the interactive amino acid residues at the interface between B-and D-helixes are conserved. These amino acid residues are believed to play a significant role in the stability of protein oligomers. | TANG Lin SUN Qing’an LI Qingguo HUANG Yibo WEI Qingqing ZHANG Yi HU Jun ZHANG Zhihong LI Minqian YANG Fujia | 2001 | Chinese Science Bulletin2001，46，22： | 2 |
| 11 | Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival显示文摘Genome-wide association studies have suggested a link between primary open-angle glaucoma and the function of ABCA1.ABCA1 is a key regulator of cholesterol efflux and the biogenesis of high-density lipoprotein(HDL) particles. Here, we showed that the POAG risk allele near ABCA1 attenuated ABCA1 expression in cultured cells. Consistently, POAG patients exhibited lower ABCA1 expression, reduced HDL, and higher cholesterol in white blood cells. Ablation of Abca1 in mice failed to form HDL, leading to elevated cholesterol levels in the retina. Counting retinal ganglion cells(RGCs) by using an artificial intelligence(AI) program revealed that Abca1-deficient mice progressively lost RGCs with age. Single-cell RNA sequencing(scRNA-seq) revealed aberrant oxidative phosphorylation in the Abca1-/-retina, as well as activation of the mTORC1 signaling pathway and suppression of autophagy. Treatment of Abca1-/-mice using atorvastatin reduced the cholesterol level in the retina,thereby improving metabolism and protecting RGCs from death. Collectively, we show that lower ABCA1 expression and lower HDL are risk factors for POAG. Accumulated cholesterol in the Abca1-/-retina causes profound aberrant metabolism, leading to a POAG-like phenotype that can be prevented by atorvastatin. Our findings establish statin use as a preventive treatment for POAG associated with lower ABCA1 expression. | Jialiang Yang Yuhong Chen Tongdan Zou Bai Xue Fang Yang Xiangzhou Wang Yibo Huo Boyun Yan Yuxia Xu Shiyu He Yi Yin Jing Wang Xiong Zhu Lin Zhang Yu Zhou Zhengfu Tai Ping Shuai Man Yu Qian Luo Yilian Cheng Bo Gong Xianjun Zhu Jing Zhang Xinghuai Sun Ying Lin Houbin Zhang Zhenglin Yang | 2023 | Science China(Life Sciences)2023，66，2： | 2 |
| 12 | Computational spectropolarimetry with a tunable liquid crystal metasurface显示文摘While conventional photodetectors can only measure light intensity,the vectorial light field contains much richer information,including polarization and spectrum,that are essential for numerous applications ranging from imaging to telecommunication.However,the simultaneous measurement of multi-dimensional light field information typically requires the multiplexing of dispersive or polarization-selective elements,leading to excessive system complexity.Here,we demonstrate a near-infrared spectropolarimeter based on an electrically-tunable liquid crystal metasurface.The tunable metasurface,which acts as an encoder of the vectorial light field,is tailored to support high-quality-factor guided-mode resonances with diverse and anisotropic spectral features,thus allowing the full Stokes parameters and the spectrum of the incident light to be computationally reconstructed with high fidelity.The concept of using a tunable metasurface for multi-dimensional light field encoding may open up new horizons for developing vectorial light field sensors with minimized size,weight,cost,and complexity. | Yibo Ni Chen Chen Shun Wen Xinyuan Xue Liqun Sun Yuanmu Yang | 2022 | eLight2022，2，1： | 2 |
| 13 | A non-metabolic function of hexokinase 2 in small cell lung cancer:promotes cancer cell stemness by increasing USP11-mediated CD133 stability显示文摘Background:Maintenance of cancer stem-like cell(CSC)stemness supported by aberrantly regulated cancer cell metabolism is critical for CSC self-renewal and tumor progression.As a key glycolytic enzyme,hexokinase 2(HK2)plays an instrumental role in aerobic glycolysis and tumor progression.However,whether HK2 directly contribute to CSC stemness maintenance in small cell lung cancer(SCLC)is largely unclear.In this study,we aimed to investgate whether HK2 independent of its glycolytic activity is directly involved in stemness maintenance of CSC in SCLC.Methods:Immunoblotting analyses were conducted to determine the expression of HK2 in SCLC CSCs and their differentiated counterparts.CSC-like properties and tumorigenesis of SCLC cells with or without HK2 depletion or overexpression were examined by sphere formation assay and xenograft mouse model.Immunoprecipitation and mass spectrometry analyses were performed to identify the binding proteins of CD133.The expression levels of CD133-associated and CSC-relevant proteins were evaluated by immunoblotting,immunoprecipitation,immunofluorescence,and immunohistochemistry assay.RNA expression levels of Nanog,POU5F1,Lin28,HK2,Prominin-1 were analyzed through quantitative reverse transcription PCR.Polyubiquitination of CD133 was examined by in vitro or in vivo ubiquitination assay.CD133+cells were sorted by flow cytometry using an anti-CD133 antibody.Results:We demonstrated that HK2 expression was much higher in CSCs of SCLC than in their differentiated counterparts.HK2 depletion inhibited CSC stemness and promoted CSC differentiation.Mechanistically,nonmitochondrial HK2 directly interacted with CD133 and enhanced CD133 expression without affecting CD133 mRNA levels.The interaction of HK2 and CD133 promoted the binding of the deubiquitinase ubiquitin-specific protease 11(USP11)to CD133,thereby inhibiting CD133 polyubiquitylation and degradation.HK2-mediated upregulation of CD133 expression enhanced the expression of cell renewal regulators,SCLC cell stemness,and tumor growth in mice.In addition,HK2 expression was positively correlated with CD133 expression in human SCLC specimens,and their expression levels were associated with poor prognosis of SCLC patients.Conclusions:These results revealed a critical non-metabolic function of HK2 in promotion of cancer cell stemness.Our findings provided new insights into the multifaceted roles of HK2 in tumor development. | Juhong Wang Fei Shao Yannan Yang Wei Wang Xueying Yang Renda Li Hong Cheng Sijin Sun Xiaoli Feng Yibo Gao Jie He Zhimin Lu | 2022 | Cancer Communications2022，42，10： | 2 |
| 14 | MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma显示文摘 | Xiaohui Xu Zhaoli Chen Xiaohong Zhao Jiwen Wang Dapeng Ding Zhen Wang Fengwei Tan Xiaogang Tan Fang Zhou Jian Sun Nan Sun Yibo Gao Kang Shao Ning Li Bin Qiu Jie He | 2012 | Biochemical and Biophysical Research Communications2012，，4： | 2 |
| 15 | BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: A review显示文摘 | Xin An Amit K. Tiwari Yibo Sun Pei-Rong Ding Charles R. Ashby Zhe-Sheng Chen | 2010 | Leukemia Research2010，，10： | 1 |
| 16 | Comparison of Segmentation Algorithms for Detecting Myocardial Infarction Using Late Gadolinium Enhancement Magnetic Resonance Imaging显示文摘Objective:The aim of this study was to validate the accuracy of a new automatic method for scar segmentation and compare its performance with that of two other frequently used segmentation algorithms.Methods:Twenty-six late gadolinium enhancement cardiovascular magnetic resonance images of diseased hearts were segmented by the full width at half maximum(FWHM)method,the n standard deviations(n SD)method,and our new automatic method.The results of the three methods were compared with the consensus ground truth obtained by manual segmentation of the ventricular boundaries.Results:Our automatic method yielded the highest Dice score and the lowest volume difference compared with the consensus ground truth segmentation.The n SD method produced large variations in the Dice score and the volume difference.The FWHM method yielded the lowest Dice score and the greatest volume difference compared with the automatic,6SD,and 8SD methods,but resulted in less variation when different observers segmented the images.Conclusion:The automatic method introduced in this study is highly reproducible and objective.Because it requires no manual intervention,it may be useful for processing large datasets produced in clinical applications. | Yibo Sun Dongdong Deng Liping Sun Yi He Hui Wang Jianzeng Dong | 2020 | Cardiovascular Innovations and Applications2020，，4： | 1 |
| 17 | Study on energy attenuation of ultrasonic guided waves going through girth welds显示文摘 | LI Yibo SUN Liying SONG Zhidong | 2006 | Ultrasonics2006，44，1： | 1 |
| 18 | Polymeric architectures of bismuth citrate based on dimeric building blocks显示文摘Four bismuth complexes, (H2En)[Bi2(cit)2(H2O)4/3]·(H2O)x (1), (H2En)3[Bi2(cit)2Cl4]·(H2O)x (2), (HPy)2[Bi2(cit)2(H2O)8/5]·(H2O)x (3) and (H2En)[Bi2(cit)2](H2O)x (4) [cit = citrate4-; En = ethylenediamine; Py = pyridine] have been synthesized and crystallized. The crystal structures reveal that the basic building blocks in all of these complexes are bismuth citrate dimeric units which combine to form polymeric architectures. The embedded protonated ethylenediamine and pyridine moieties in the polymeric frameworks have been identified by X-ray crystallography and solid-state cross polarization/magic angle spinning (CP/MAS) 13C NMR. Based on the framework of complex 1, a structural model of a clinically used antiulcer drug, ranitidine bismuth citrate (RBC) was generated. The behavior of the protonated amine-bismuth citrate complexes in acidic aqueous solution has been studied by electrospray ionization-mass spectrometry (ESI-MS). | YANG Nan AN Yan CAI JiWen HU LiHong ZENG YiBo MAO ZongWan CHEN GuanHua SUN HongZhe | 2010 | Science China Chemistry2010，53，10： | 1 |
| 19 | Elevated Plasma Homocysteine Was Associated With Hemorrhagic and Ischemic Stroke, but Methylenetetrahydrofolate Reductase Gene C677T Polymorphism Was a Risk Factor for Thrombotic Stroke: A Multicenter Case-Control Study in China显示文摘 | Zhaohui Li Li Sun Hongye Zhang Yuhua Liao Daowen Wang Bingrang Zhao Zhiming Zhu Jizong Zhao Aiqun Ma Yu Han Yibo Wang Yi Shi Jue Ye Rutai Hui | 2003 | Stroke: Journal of the American Heart Association2003，，9： | 1 |
| 20 | A 3D QSAR Study of Betulinic Acid Derivatives as Anti-Tumor Agents Using Topomer Co MFA:Model Building Studies and Experimental Verification显示文摘 | Ding Weimin Sun Miao Luo Shaman Xu Tao Cao Yibo Yan Xiufeng Wang Yang | 2013 | Molecules2013，18，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员