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| 1 | Recent Progress in Distributed Optical Fiber Raman Photon Sensors at China Jiliang University显示文摘在在中国 Jiliang 大学(CJLU ) 的完整的分布式的纤维拉曼光子传感器的研究,生产和应用的最近的进步的简短评论被介绍。以便改进测量距离,精确性,空间分辨率,多参数大小的能力,和完整的分布式的纤维传感器系统的智力,一种新一代纤维传感器技术基于光纤维,非线性的散布熔化原则被建议。一系列新一代完整的分布式的纤维传感器被调查并且设计,它由新产生组成极端长的距离散布与一个纤维拉曼放大器综合的光子传感器的完整的分布式的纤维拉曼和瑞利,汽车修正完整的分布式的纤维拉曼光子温度传感器基于拉曼关联双来源,完整的分布式的纤维拉曼光子温度传感器基于编码的脉搏采购原料,完整的分布式的纤维拉曼光子温度传感器 | Zaixuan ZHANG | 2012 | Photonic Sensors2012，2，2： | 8 |
| 2 | Symmetry Reduction and Exact Solutions of a Hyperbolic Monge-Ampère Equation显示文摘By means of the classical symmetry method,a hyperbolic Monge-Ampère equation is investigated.The symmetry group is studied and its corresponding group invariant solutions are constructed.Based on the associated vector of the obtained symmetry,the authors construct the group-invariant optimal system of the hyperbolic Monge-Ampère equation,from which two interesting classes of solutions to the hyperbolic Monge-Ampère equation are obtained successfully. | Zhongzhou DONG Yong CHEN Dexing KONG Zenggui WANG | 2012 | Chinese Annals of Mathematics,Series B2012，33，2： | 4 |
| 3 | New isotope 265Bh显示文摘 | Z. G. Gan J. S. Guo X. L. Wu Z. Qin H. M. Fan X. G. Lei H. Y. Liu B. Guo H. G. Xu R. F. Chen C. F. Dong F. M. Zhang H. L. Wang C. Y. Xie Z. Q. Feng Y. Zhen L. T. Song P. Luo H. S. Xu X. H. Zhou G. M. Jin Zhongzhou Ren | 2004 | The European Physical Journal A2004，，3： | 1 |
| 4 | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation显示文摘co 翻译的指向或插入能分泌并且膜蛋白质进 endoplasmic 蜂窝胃(嗯) 一个关键生物过程被信号识别粒子(SRP ) 调停。在优核质, SRP68-SRP72 (SRP68/72 ) heterodimer 在蛋白质 translocation 起一个必要作用。然而,二最大的 SRP 蛋白质, SRP68 和 SRP72 的结构的信息,被限制,特别关于他们的相互作用。此处,我们在 2.91 点报导人的 apo-SRP72 和 SRP68/72 建筑群的第一水晶结构吗?并且 1.7?分辨率分别地。SRP72 的 SRP68 有约束力的领域包含四次不正常的 tetratricopeptide 重复(TPR ) 和一顶灵活 C 终端帽子。Apo-SRP72 在答案主要作为 dimers 存在。为了绑在 SRP68, SRP72 homodimer disassociates,和不可缺少的 C 终端帽子,经历一个显著 conformational 变化帮助 SRP68/72 heterodimer 的形成。SRP68 的 A 23 残余多肽为到通过它的不平常地恐水病、扩大的表面的 SRP72 的紧密的绑定是足够的。结构,生物物理,并且 mutagenesis 分析表明联系癌症的变化破坏 SRP68-SRP72 相互作用和他们的合作本地化与嗯在哺乳动物的房间。结果在调停 SRP 的蛋白质 translocation 加亮 SRP68-SRP72 相互作用的必要角色并且为疾病诊断, pathophysiology,和药设计提供一个结构的基础。 | Yina Gao Qi Zhang Yue Lang Yang Liu Xiaofei Dong Zhenhang Chen Wenli Tian Jun Tang Wei Wu Yufeng Tong Zhongzhou Chen | 2017 | Journal of Molecular Cell Biology2017，9，3： | 1 |
| 5 | GATA2^(−/−) human ESCs undergo attenuatedendothelial to hematopoietic transition andthereafter granulocyte commitment显示文摘Background: Hematopoiesis is a progressive process collectively controlled by an elaborate network of transcriptionfactors (TFs). Among these TFs, GATA2 has been implicated to be critical for regulating multiple steps of hematopoiesisin mouse models. However, whether similar function of GATA2 is conserved in human hematopoiesis, especially duringearly embryonic development stage, is largely unknown.Results: To examine the role of GATA2 in human background, we generated homozygous GATA2 knockout humanembryonic stem cells (GATA2^(−/−) hESCs) and analyzed their blood differentiation potential. Our results demonstratedthat GATA2^(−/−) hESCs displayed attenuated generation of CD34^(+)CD43^(+) hematopoietic progenitor cells (HPCs), due tothe impairment of endothelial to hematopoietic transition (EHT). Interestingly, GATA2^(−/−) hESCs retained the potentialto generate erythroblasts and macrophages, but never granulocytes. We further identified that SPI1 downregulationwas partially responsible for the defects of GATA2^(−/−) hESCs in generation of CD34^(+)CD43^(+) HPCs and granulocytes.Furthermore, we found that GATA2^(−/−) hESCs restored the granulocyte potential in the presence of Notch signaling.Conclusion: Our findings revealed the essential roles of GATA2 in EHT and granulocyte development throughregulating SPI1, and uncovered a role of Notch signaling in granulocyte generation during hematopoiesis modeled byhuman ESCs. | Ke Huang Juan Du Ning Ma Jiajun Liu Pengfei Wu Xiaoya Dong Minghui Meng Wenqian Wang Xin Chen Xi Shi Qianyu Chen Zhongzhou Yang Shubin Chen Jian Zhang Yuhang Li Wei Li Yi Zheng Jinglei Cai Peng Li Xiaofang Sun Jinyong Wang Duanqing Pei Guangjin Pan | 2015 | Cell Regeneration2015，4，1： | 0 |
| 6 | Research on two-proton radioactivity in density-dependent cluster model显示文摘The density-dependent cluster model(DDCM) provides a unified framework to study α decay,heavy-cluster radioactivity,and proton emission.Two-proton(2p) radioactivity is a rare decay mode of exotic nuclei near or beyond the drip-line.It is of great interest to explore the applicability of DDCM to this exotic decay mode.In this work,DDCM has been extended to study 2p radioactivity.The 2p-radioactivity half-lives are calculated for several known 2p-emitters,including19Mg,45Fe,48Ni,54Zn,and67Kr.The theoretical results are in good agreement with the experimental data,with the standard deviations comparable to or smaller than those given by some other theoretical models and empirical formulas.We also predict the half-lives of a number of possible 2p-emitters with S2p<0 and Sp> 0 using the new data from AME2020 and NUBASE2020.These predictions serve as useful references for future experimental and theoretical investigations on 2p radioactivity. | Ziyi Yuan Dong Bai Zhen Wang Zhongzhou Ren Dongdong Ni | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，2： | 0 |
| 7 | PHB介导的HIRA复合物调控人胚胎干细胞的表观--代谢环路显示文摘文章简介染色质地貌和细胞代谢对细胞命运决定有着重要的作用,但人们对它们之间的相互作用却了解甚少。课题组运用基因组范围的si RNA筛选,发现PHB对于维持人胚胎干细胞的自我更新具有重要的作用。 | Huanhuan Li Ping Lai Jinping Jia Yawei Song Qing Xia Kaimeng Huang Na He Wangfang Ping Jiayu Chen Zhongzhou Yang Jiao Li Mingze Yao Xiaotao Dong Jicheng Zhao Chunhui Hou Miguel A.Esteban Shaorong Gao Duanqing Pei Andrew P.Hutchins 姚红杰 Zhexin Zhu Chunliang Li Yanwu Zeng Jianyi Ding Zepeng Qu Junjie Gu Laixiang Ge Fan Tang Xin Huang Chenlin Zhou Ping Wang Deyou Zheng 金颖 | 2018 | 科学新闻2018，0，4： | 0 |
| 8 | RNA解旋酶DDX5通过miRNA调控RYBP依赖和非依赖于PRC1的双重功能而抑制体细胞重编程显示文摘RNA结合蛋白除了调控细胞内动态平衡的功能外,RNA结合蛋白在谱系分化和维持细胞身份中扮演着重要角色。 | Huanhuan Li Ping Lai Jinping Jia Yawei Song Qing Xia Kaimeng Huang Na He Wangfang Ping Jiayu Chen Zhongzhou Yang Jiao Li Mingze Yao Xiaotao Dong Jicheng Zhao Chunhui Hou Miguel A.Esteban Shaorong Gao Duanqing Pei Andrew P.Hutchins 姚红杰 | 2018 | 科学新闻2018，0，4： | 0 |
| 9 | Master microRNA-222 regulates cardiac microRNA maturation and triggers Tetralogy of Fallot显示文摘Dear Editor,Tetralogy of Fallot(TOF)is the most common complex congenital heart disease.Besides gene mutations and copy number variants,altered protein function induced by posttranscriptional or translational regulation also contributes to the onset of TOF.1 MiRNAs are short noncoding RNAs that bind to the 3’-UTR of target mRNAs to repress protein production.However,the causal link between miRNAs and TOF and the underlying mechanism has not been established. | Chao Li Hongdou Li Xiaoying Yao Dong Liu Yongming Wang Xinyi Huang Zhongzhou Yang Wufan Tao Jian-Yuan Zhao Hongyan Wang | 2022 | Signal Transduction and Targeted Therapy2022，7，6： | 0 |
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