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| 1 | Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide analogs显示文摘 | Fengmin Lu Jie Wang Xiangmei Chen Dongping Xu Ningshao Xia | 2017 | Frontiers of Medicine2017，11，4： | 28 |
| 2 | FERONIA Receptor Kinase Controls Seed Size in Arabidopsis thaliana显示文摘Dear Editor, Plants have evolved elaborate mechanisms by which cell elongation regulation is coupled to the environmental signals.The plasma membrane receptor kinase FERONIA (FER) has emerged as an important regulatory node in controlling cell elongation and hormone crosstalk (Guo et al.,2009;Deslauriers and Larsen,2010;Duan et al.,2010;Yu et al.,2012).Initially reported to inhibit pollen tube elongation during fertilization (Escobar-Restrepo et al.,2007),FER has been since found to promote cell elongation in leaves and root hairs (Guo et al.,2009;Duan et al.,2010). | Feng Yu Jian Li Yuan Huang Li Liu Dongping Li Liangbi Chen Sheng Luan | 2014 | Molecular Plant2014，7，5： | 16 |
| 3 | Near-surface Geothermal Gradient Observation and Geothermal Analyses in the Xianshuihe Fault Zone,Eastern Tibetan Plateau显示文摘The Xianshuihe fault(XSHF) zone, characterized by intense tectonic activity, is located at the southwest boundary of the Bayan Har block, where several major earthquakes have occurred, including the 2008 Wenchuan and the 2013 Lushan earthquakes. This study analysed underground temperature sequence data for four years at seven measuring points at different depths(maximum depth: 18.9 m) in the southeastern section of the XSHF zone. High-frequency atmospheric noise was removed from the temperature sequences to obtain relatively stable temperature fields and heat fluxes near the measurement points. Our measurements show that the surrounding bedrock at(the seven stations distributed in the fault zone) had heat flux values range from-41.0 to 206 m W/m^2, with a median value of 54.3 m W/m^2. The results indicate a low heat flux in the northern section of DaofuKangting and a relatively high heat flux in the southern section of Kangting, which is consistent with the temperature distributions of the hot springs near the fault. Furthermore, our results suggest that the heat transfer in this field results primarily from stable underground heat conduction. In addition, the underground hydrothermal activity is also an obvious factor controlling the geothermal gradient. | LIU Qianqian SHI Yanan WEI Dongping HAN Peng CHEN Shunyun LIU Peixun LIU Liqiang | 2017 | Acta Geologica Sinica(English Edition)2017，91，2： | 8 |
| 4 | A green and effective corrosion inhibitor of functionalized carbon dots显示文摘In this work, a green and effective corrosion inhibitor of functionalized carbon dots(FCDs) was synthesized by the conjugation of imidazole and citric acid carbon dots(CA-CDs). The corrosion inhibition behavior of FCDs for Q235 steel in 1 M HCl solution was systematically investigated by electrochemical analysis, corrosion morphology and adsorption isotherm. The electrochemical results implied that the as-prepared FCDs inhibitor could effectively suppress the corrosion of Q235 steel in 1 M HCl solution. At the same time, the inhibition efficiency of steel in 1 M HCl solution was more than 90% when the inhibitor concentration exceeded 100 mg/L. This excellent property was attributed to the coverage of adsorption film on the steel surface, which conformed to the Langmuir adsorption model. In addition, the analysis of adsorption isotherm displayed that the adsorption mechanism was the physicochemical interaction at the steel/solution interface. | Yuwei Ye Dongping Yang Hao Chen | 2019 | Journal of Materials Science & Technology2019，35，10： | 6 |
| 5 | Using irrigation intervals to optimize water-use efficiency and maize yield in Xinjiang,northwest China显示文摘Worldwide, scarce water resources and substantial food demands require efficient water use and high yield.This study investigated whether irrigation frequency can be used to adjust soil moisture to increase grain yield and water use efficiency(WUE) of high-yield maize under conditions of mulching and drip irrigation.A field experiment was conducted using three irrigation intervals in 2016: 6, 9, and 12 days(labeled D6, D9, and D12) and five irrigation intervals in 2017: 3, 6, 9, 12, and 15 days(D3, D6, D9, D12, and D15).In Xinjiang, an optimal irrigation quota is 540 mm for high-yield maize.The D3, D6, D9, D12, and D15 irrigation intervals gave grain yields of 19.7, 19.1–21.0, 18.8–20.0, 18.2–19.2, and 17.2 Mg ha^-1 and a WUE of 2.48, 2.53–2.80, 2.47–2.63, 2.34–2.45, and 2.08 kg m-3, respectively.Treatment D6 led to the highest soil water storage, but evapotranspiration and soil-water evaporation were lower than other treatments.These results show that irrigation interval D6 can help maintain a favorable soil-moisture environment in the upper-60-cm soil layer, reduce soilwater evaporation and evapotranspiration, and produce the highest yield and WUE.In this arid region and in other regions with similar soil and climate conditions, a similar irrigation interval would thus be beneficial for adjusting soil moisture to increase maize yield and WUE under conditions of mulching and drip irrigation. | Guoqiang Zhang Dongping Shen Bo Ming Ruizhi Xie Xiuliang Jin Chaowei Liu Peng Hou Jun Xue Jianglu Chen Wanxu Zhang Wanmao Liu Keru Wang Shaokun Li | 2019 | The Crop Journal2019，7，3： | 4 |
| 6 | Complementation of Wild-Type and Drug-Resistant Hepatitis B Virus Genomes to Maintain Viral Replication and Rescue Virion Production under Nucleos(t)ide Analogs显示文摘As the open reading frames of hepatitis B virus(HBV)genomes are overlapping,resistance mutations(MTs)in HBV polymerase may result in stop codon MTs in hepatitis B surface proteins,which are usually detected as a mixed population with wild-type(WT)HBV.The question was raised how the coexistence of nucleos(t)ide analogs(NAs)resistance MTs and WT sequences affects HBV replication.In the present study,HBV genomes with frequently detected reverse transcriptase(RT)/surface truncation MTs,rtA181T/sW172^*,rtV191I/sW182^*and rtM204I/sW196^*,were phenotypically characterized alone or together with their WT counterparts in different ratios by transient transfection in the absence or presence of Nas.In the absence of Nas,RT/surface truncation MTs impaired the expression and secretion of HBV surface proteins,and had a dose-dependent negative effect on WT HBV virion secretion.However,in the presence of Nas,coexistence of MTs with WT maintained viral replication,and the presence of WT was able to rescue the production of MT HBV virions.Our findings reveal that complementation of WT and MT HBV genomes is highly effective under drug treatment. | Chunchen Wu Baolin Li Xiaoyong Zhang Kaitao Zhao Yingshan Chen Yifei Yuan Yan Liu Rongjuan Chen Dongping Xu Xinwen Chen Mengji Lu | 2019 | Virologica Sinica2019，34，4： | 4 |
| 7 | Model predictive control of rigid spacecraft with two variable speed control moment gyroscopes显示文摘In this paper, an attitude maneuver control problem is investigated for a rigid spacecraft using an array of two variable speed control moment gyroscopes(VSCMGs)with gimbal axes skewed to each other. A mathematical model is constructed by taking the spacecraft and the gyroscopes together as an integrated system, with the coupling interaction between them considered. To overcome the singular issues of the VSCMGs due to the conventional torque-based method, the first-order derivative of gimbal rates and the second-order derivative of the rotor spinning velocity, instead of the gyroscope torques, are taken as input variables. Moreover, taking external disturbances into account,a feedback control law is designed for the system based on a method of nonlinear model predictive control(NMPC). The attitude maneuver can be realized fast and smoothly by using the proposed controller in this paper. | Pengcheng WU Hao WEN Ti CHEN Dongping JIN | 2017 | Applied Mathematics and Mechanics(English Edition)2017，38，11： | 3 |
| 8 | MAP3K2 augments Th1 cell differentiation via IL-18 to promote T cell-mediated colitis显示文摘T cell-mediated immunity in the intestine is stringently controlled to ensure proper immunity against pathogenic microbes and to prevent autoimmunity,a known cause of inflammatory bowel disease.However,precisely how T cells regulate intestine immunity remains to be fully understood.In this study,we found that mitogen-activated protein kinase kinase kinase 2(MAP3K2)is required for the CD4^(+)T cell-mediated inflammation in the intestine.Using a T cell transfer colitis model,we found that MAP3K2-deficient naïve CD4^(+)T cells had a dramatically reduced ability to induce colitis compared to wild type T cells.In addition,significantly fewer IFN-γ-but more IL-17A-producing CD4^(+)T cells in the intestines of mice receiving MAP3K2-deficient T cells than in those from mice receiving wild type T cells was observed.Interestingly,under well-defined in vitro differentiation conditions,MAP3K2-deficient naïve T cells were not impaired in their ability to differentiate into Th1,Th17 and Treg.Furthermore,the MAP3K2-regulated colitis severity was mediated by Th1 but not Th17 cells in the intestine.At the molecular level,we showed that MAP3K2-mediated Th1 cell differentiation in the intestine was regulated by IL-18 and required specific JNK activation.Together,our study reveals a novel regulatory role of MAP3K2 in intestinal T cell immunity via the IL-18-MAP3K2-JNK axis and may provide a novel target for intervention in T cell-mediated colitis. | Ningbo Wu Dongping Chen Hongxiang Sun Jianmei Tan Yao Zhang Tianyu Zhang Yuheng Han Hongzhi Liu Xinxing Ouyang Xiao-Dong Yang Xiaoyin Niu Jie Zhong Zhengting Wang Bing Su | 2021 | Science China(Life Sciences)2021，64，3： | 3 |
| 9 | L.S.gratefully acknowledges the financial support from the Engineering and Physical Sciences Research Council(Nos.EP/L022559/1,EP/L022559/2,EP/V050311/1,and EP/W004399/1);Royal Society(Nos.RG130230 and IE161214);H2020 Marie Skłodowska-Curie Actions(No.790666);J.S.Z.was supported by a PhD Studentship provided by Queen Mary University of London and China Scholarship Council(CSC).显示文摘Advanced energy and sensor devices with novel applications(e.g.,mobile equipment,electric vehicles,and medical-healthcare systems)are one of the important foundations of modern intelligent life.However,there are still some scientific issues that seriously hinder the further development of devices,including unsustainability,high material cost,complex fabrication process,safety issues,and unsatisfactory performance.Nanocellulose has aroused tremendous attention in recent decades,because of its abundant resources,renewability,degradability,low-cost,and unique physical/chemical properties.These merits make nanocellulose as matrix materials to fabricate advanced functional composites for use in energy-related fields extremely competitive.Here,we comprehensively discuss the recent progress of nanocellulose for emerging energy storage/harvesting and sensor applications.The preparation methodologies of nanocellulose combined with conductive materials are firstly highlighted,including carbon materials,conductive polymers,metal/metal oxide nanoparticles,metal-organic frameworks(MOFs),and covalent organic frameworks(COFs).We then focus on the nanocellulose-based advanced materials for the application in the areas of supercapacitors,lithium-ion batteries,solar cells,triboelectric nanogenerators,moisture-enabled electric generators,and sensors.Lastly,the future research directions of nanocellulose-based functional materials in energy-related devices are presented. | Lumin Chen Somia Yassin Hussain Abdalkarim Houyong Yu Xiang Chen Dongping Tang Yingzhan Li Kam Chiu Tam | 2022 | Nano Research2022，15，8： | 2 |
| 10 | Single‑Atom Cobalt‑Based Electrochemical Biomimetic Uric Acid Sensor with Wide Linear Range and Ultralow Detection Limit显示文摘Uric acid(UA)detection is essential in diagnosis of arthritis,preeclampsia,renal disorder,and cardiovascular diseases,but it is very challenging to realize the required wide detection range and low detection limit.We present here a single-atom catalyst consisting of Co(Ⅱ)atoms coordinated by an average of 3.4 N atoms on an N-doped graphene matrix(A-Co-NG)to build an electrochemical biomimetic sensor for UA detection.The A-Co-NG sensor achieves a wide detection range over 0.4-41,950μM and an extremely low detection limit of 33.3±0.024 nM,which are much better than previously reported sensors based on various nanostructured materials.Besides,the A-Co-NG sensor also demonstrates its accurate serum diagnosis for UA for its practical application.Combination of experimental and theoretical calculation discovers that the catalytic process of the A-Co-NG toward UA starts from the oxidation of Co species to form a Co^3+-OH-UA*,followed by the generation of Co^3+-OH+^*UA_H,eventually leading to N-H bond dissociation for the formation of oxidized UA molecule and reduction of oxidized Co^3+to Co^2+for the regenerated A-Co-NG.This work provides a promising material to realize UA detection with wide detection range and low detection limit to meet the practical diagnosis requirements,and the proposed sensing mechanism sheds light on fundamental insights for guiding exploration of other biosensing processes. | Fang Xin Hu Tao Hu Shihong Chen Dongping Wang Qianghai Rao Yuhang Liu Fangyin Dai Chunxian Guo Hong Bin Yang Chang Ming Li | 2021 | Nano-Micro Letters2021，13，1： | 2 |
| 11 | Comparison of the Molecular Interaction Volume Model with the Wagner Formulae in the Zn-Pb-In and Zn-Sn-Cd-Pb Dilute Solutions显示文摘The coordination numbers in the molecular interaction volume model (MIVM) can be calculated from the common physical quantities of pure liquid metals. A notable feature of the model lie in its capability to predict the thermodynamic properties of solutes in the Zn-Pb-ln and Zn-Sn-Cd-Pb dilute solutions using only the binary infinite dilute activity coefficients, and the predicted values are in good agreement with the experimental data of the dilute solutions. | Dongping TAO Zhuo CHEN Dunfang LI Yifeng GAO Qianghua SHEN School of Materials and Metallurgical Engineering, Kunming University of Science and Technology, Kunming 650093, China | 2004 | Journal of Materials Science & Technology2004，20，3： | 2 |
| 12 | Effect of Synthetic Method and Reductant on the Morphology and Photocatalytic Hydrogen Evolution Performance of Ru Nanoparticles显示文摘 | KONG Chao HAN Yanxia HOU Lijie CHEN Dongping WU Bowan | 2017 | Chemical Research in Chinese Universities2017，33，5： | 2 |
| 13 | Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: a prospective study显示文摘 | Chunping Wang Yinying Lu Yan Chen Yongyi Feng Linjing An Xinzhen Wang Shuhui Su Wenlin Bai Lin Zhou Yongping Yang Dongping Xu | 2009 | Clinical & Experimental Metastasis2009，，7： | 1 |
| 14 | Trace elements in fish from Taihu Lake, China: Levels, associated risks, and trophic transfer显示文摘 | Ying Hao Liang Chen Xiaolan Zhang Dongping Zhang Xinyu Zhang Yingxin Yu Jiamo Fu | 2013 | Ecotoxicology and Environmental Safety2013，，： | 1 |
| 15 | Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: a prospective study显示文摘 | Chunping Wang Yinying Lu Yan Chen Yongyi Feng Linjing An Xinzhen Wang Shuhui Su Wenlin Bai Lin Zhou Yongping Yang Dongping Xu | 2009 | Clinical & Experimental Metastasis2009，，7： | 1 |
| 16 | Graphene nanoplate-Pt composite as a high performance electrocatalyst for direct methanol fuel cells显示文摘 | Huajie Huang Haiqun Chen Dongping Sun Xin Wang | 2012 | Journal of Power Sources2012，，： | 1 |
| 17 | Wave control of a flexible space tether based on elastic metamaterials显示文摘This study proposes a spider‐web elastic metamaterial to suppress vibrations in space slender structures,such as flexible space tethers.The metamaterial consists of unit cells that are periodically distributed on the space tether to obtain band gaps.The finite element model of the unit cell is established by employing the absolute nodal coordinate formulation(ANCF)due to the large deformation of the structure.The eigenfrequencies and corresponding vibration modes of the unit cell are obtained by ANCF.Moreover,the band gap of the unit cell is calculated based on the phonon crystal theory.The relationship between the vibration modes and the band gaps is analyzed.Finally,an experiment is conducted to verify the vibration transmission characteristics of finite period cells.The results show the effectiveness of the spider‐web elastic metamaterial for vibration suppression of a flexible tether.This study provides insights into the use of elastic metamaterials for vibration isolation in space tether systems. | Yexiong Huang Enmin Chen Jialiang Sun Dongping Jin | 2023 | International Journal of Mechanical System Dynamics2023，3，1： | 1 |
| 18 | FERONIA receptor kinase pathway suppresses abscisic acid signaling in Arabidopsis by activating ABI2 phosphatase显示文摘 | Feng Yu Lichao Qian Candida Nibau Qiaohong Duan Daniel Kita Kathryn Levasseur Xiaoqian Li Changqing Lu Hui Li Congcong Hou Legong Li Bob B. Buchanan Liangbi Chen Alice Y. Cheung Dongping Li Sheng Luan | 2012 | Proceedings of the National Academy of Sciences2012，，36： | 1 |
| 19 | Graphene nanoplate-Pt composite as a high performance electrocatalyst for direct methanol fuel cells显示文摘 | HUANG Huajie CHEN Haiqun SUN Dongping | 2012 | Journal of Power Sources2012，，204： | 1 |
| 20 | Mechanosensitive Ion Channel TMEM63A Gangs Up with Local Macrophages to Modulate Chronic Post-amputation Pain显示文摘Post-amputation pain causes great sufering to amputees,but still no efective drugs are available due to its elusive mechanisms.Our previous clinical studies found that surgical removal or radiofrequency treatment of the neuroma at the axotomized nerve stump efectively relieves the phantom pain aficting patients after amputation.This indicated an essential role of the residual nerve stump in the formation of chronic post-amputation pain(CPAP).However,the molecular mechanism by which the residual nerve stump or neuroma is involved and regulates CPAP is still a mystery.In this study,we found that nociceptors expressed the mechanosensitive ion channel TMEM63A and macrophages infltrated into the dorsal root ganglion(DRG)neurons worked synergistically to promote CPAP.Histology and qRT-PCR showed that TMEM63A was mainly expressed in mechanical pain-producing non-peptidergic nociceptors in the DRG,and the expression of TMEM63A increased signifcantly both in the neuroma from amputated patients and the DRG in a mouse model of tibial nerve transfer(TNT).Behavioral tests showed that the mechanical,heat,and cold sensitivity were not afected in the Tmem63a-/-mice in the naïve state,suggesting the basal pain was not afected.In the infammatory and post-amputation state,the mechanical allodynia but not the heat hyperalgesia or cold allodynia was signifcantly decreased in Tmem63a-/-mice.Further study showed that there was severe neuronal injury and macrophage infltration in the DRG,tibial nerve,residual stump,and the neuromalike structure of the TNT mouse model,Consistent with this,expression of the pro-infammatory cytokines TNFα,IL-6,and IL-1βall increased dramatically in the DRG.Interestingly,the deletion of Tmem63a signifcantly reduced the macrophage infltration in the DRG but not in the tibial nerve stump.Furthermore,the ablation of macrophages signifcantly reduced both the expression of Tmem63a and the mechanical allodynia in the TNT mouse model,indicating an interaction between nociceptors and macrophages,and that these two factors gang up together to regulate the formation of CPAP.This provides a new insight into the mechanisms underlying CPAP and potential drug targets its treatment. | Shaofeng Pu Yiyang Wu Fang Tong Wan-Jie Du Shuai Liu Huan Yang Chen Zhang Bin Zhou Ziyue Chen Xiaomeng Zhou Qingjian Han Dongping Du | 2023 | Neuroscience Bulletin2023，39，2： | 1 |
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