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| 1 | Paleomagnetic data from Early Cretaceous volcanic rocks of West Liaoning:Evidence for intracontinental rotation显示文摘Detailed rock magnetic studies of 55 lavas from Yixian and Fuxin area, West Liaoning, show the primary carriers of remanence to be pseudo-single domain ti-tanomagnetite. K/Ar dating indicates that the volcanic sequence spans 93 to 133 Ma. Stepwise thermal demagnetization successfully isolated well-defined characteristic magnetization (ChRM) in all lavas thermal-treated above 250℃ The mean paleodirections are D/I=5.9°/58.8° (α95 = 2.9°) and D/I =179.2°/-59.9° (α95 = 5.2°) for 27 normally magnetized flows and 28 reversibly magnetized flows, respectively. It indicates that since the Early Cretaceous there is no significant horizontal movement and rotation between the Yixian-Fuxin area and Eurasia. However, Korea Peninsula may have undergone a clockwise rotation of 33.9° relative to the Yixian-Fuxin area during the Cretaceous. On the basis of characteristics of hotspot origins (core-mantle boundary or upper mantle), the clockwise rotation of Korea Peninsula relative to Eurasia is assumed to be | ZHU Rixiang SHAO Ji’an PAN Yongxin SHI Ruiping SHI Guanghai LI Darning | 2002 | Chinese Science Bulletin2002，47，21： | 31 |
| 2 | Mineralogical and geochemical features of sulfide chimneys from the 49°39′E hydrothermal field on the Southwest Indian Ridge and their geological inferences显示文摘During January–May in 2007,the Chinese research cruise DY115-19 discovered an active hydrothermal field at 49°39′E/37°47′S on the ultraslow spreading Southwest Indian Ridge (SWIR).This was also the first active hydrothermal field found along an ultraslow-spreading ridge.We analyzed mineralogical,textural and geochemical compositions of the sulfide chimneys obtained from the 49°39′E field.Chimney samples show a concentric mineral zone around the fluid channel.The mineral assemblages of the interiors consist mainly of chalcopyrite,with pyrite and sphalerite as minor constitunets.In the intermediate portion,pyrite becomes the dominant mineral,with chalcopyrite and sphalerite as minor constitunets.For the outer wall,the majority of minerals are pyrite and sphalerite,with few chalcopyrite.Towards the outer margin of the chimney wall,the mineral grains become small and irregular in shape gradually,while minerals within interstices are abundant.These features are similar to those chimney edifices found on the East Pacific Rise and Mid-Atlantic Ridge.The average contents of Cu,Fe and Zn in our chimney samples were 2.83 wt%,45.6 wt% and 3.28 wt%,respectively.The average Au and Ag contents were up to 2.0 ppm and 70.2 ppm respectively,higher than the massive sulfides from most hydrothermal fields along mid-ocean ridge.The rare earth elements geochemistry of the sulfide chimneys show a pattern distinctive from the sulfides recovered from typical hydrothermal fields along sedimentstarved mid-ocean ridge,with the enrichment of light rare earth elements but the weak,mostly negative,Eu anomaly.This is attributed to the distinct mineralization environment or fluid compositions in this area. | TAO ChunHui LI HuaiMing HUANG Wei HAN XiQiu WU GuangHai SU Xin ZHOU Ning LIN Jian HE YongHua ZHOU JianPing | 2011 | Chinese Science Bulletin2011，56，26： | 34 |
| 3 | Efficacy and safety of a novel anti-HER2 therapeutic antibody RC48 in patients with HER2-overexpressing,locally advanced or metastatic gastric or gastroesophageal junction cancer:a single-arm phase II study显示文摘Background:Current treatment options for human epidermal growth factor receptor 2(HER2)-overexpressing gastric cancer at third-line have shown limited clinical benefit.Further,there is no specific treatment for HER2 immunohistochemistry(IHC)2+and fluorescence in-situ hybridization-negative patients.Here,we report the efficacy and safety of a novel anti-HER2 antibody RC48 for patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer.Methods:Patients with HER2-overexpressing(IHC 2+or 3+),locally advanced or metastatic gastric or gastroesophageal junction cancer who were under at least second-line therapy were eligible and received RC482.5 mg/kg alone every 2 weeks.The primary endpoint was the objective response rate(ORR)assessed by an independent review committee.Secondary endpoints included progressionfree survival(PFS),overall survival(OS),duration of response,time to progression,disease control rate,and safety.Results:Of 179 patients screened,125 were eligible and received RC48 treatment.The ORR was 24.8%(95%confidence interval[CI]:17.5%-33.3%).The median PFS and OS were 4.1 months(95%CI:3.7-4.9 months)and 7.9 months(95%CI:6.7-9.9 months),respectively.The most frequently reported adverse events were decreased white blood cell count(53.6%),asthenia(53.6%),hair loss(53.6%),decreased neutrophil count(52.0%),anemia(49.6%),and increased aspartate aminotransferase level(43.2%).Serious adverse events(SAEs)occurred in 45(36.0%)patients,and RC48-related SAEs were mainly decreased neutrophil count(3.2%).Seven patients had adverse events that led to death were not RC48-related.Conclusions:RC48 showed promising activity with manageable safety,suggesting potential application in patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer who have previously received at least two lines of chemotherapy. | Zhi Peng Tianshu Liu Jia Wei Airong Wang Yifu He Liuzhong Yang Xizhi Zhang Nanfeng Fan Suxia Luo Zhen Li Kangsheng Gu Jianwei Lu Jianming Xu Qingxia Fan Ruihua Xu Liangming Zhang Enxiao Li Yuping Sun Guohua Yu Chunmei Bai Yong Liu Jiangzheng Zeng Jieer Ying Xinjun Liang Nong Xu Chao Gao Yongqian Shu Dong Ma Guanghai Dai Shengmian Li Ting Deng Yuehong Cui Jianmin Fang Yi Ba Lin Shen | 2021 | Cancer Communications2021，41，11： | 29 |
| 4 | REE composition in scheelite and scheelite Sm-Nd dating for the Xuebaoding W-Sn-Be deposit in Sichuan显示文摘The scheelite with large size and euhedral shape from Xuebaoding, Sichuan Province is an ideal min- eral to study REE patterns and Sm-Nd dating of non-gold deposits. The scheelite has diameters of 1― 10 cm and colors of pale beige to deep orange. Most of these scheelites occur in association with beryl, cassiterite and muscovite. The rare earth elements indicate that scheelite samples from Xuebaoding W-Sn-Be deposits contain high concentrations of rare earth elements with total ΣREE+Y contents in the range of 369―1725 μg·g?1 and nearly all of these scheelite samples are enriched in LREE and depleted in HREE and have negative Eu anomalies. The REE patterns of the scheelites are similar to those of A-type granite with obvious tetrad effect, similar to that of type II scheelites. Based on reported fluid inclusion studies, the mineralizing-fluid of the Xuebaoding W-Sn-Be deposit indicates low Na activity. The REE patterns of the scheelite are probably controlled by partition coefficient in hydrothermal fluid. In the 147Sm/144Nd-143Nd/144Nd diagram, the scheelites show a linear array corresponding to an isochron age of 182.0±9.2 Ma (MSWD = 0.52). The Sm-Nd age represents the formation age of the scheelite and can indicate that the W, Sn and Be mineralization at Xuebaoding took place in the Early Yanshanian. The Sm-Nd dating result is important for the study of the multi-metal resources in western Sichuan Province. | LIU Yan DENG Jun LI ChaoFeng SHI GuangHai ZHENG AiLi | 2007 | Chinese Science Bulletin2007，52，18： | 25 |
| 5 | Bevacizumab plus capecitabine and cisplatin in Chinese patients with inoperable locally advanced or metastatic gastric or gastroesophageal junction cancer: randomized, double-blind, phase III study (AVATAR study)显示文摘 | Lin Shen Jin Li Jianming Xu Hongming Pan Guanghai Dai Shukui Qin Liwei Wang Jinwan Wang Zhenzhou Yang Yongqian Shu Ruihua Xu Lei Chen Yunpeng Liu Shiying Yu Lilian Bu Yongzhe Piao | 2015 | Gastric Cancer2015，，1： | 7 |
| 6 | Reversible and irreversible heat generation of NCA/Si–C pouch cell during electrochemical energy-storage process显示文摘To meet the requirements of electronic vehicles(EVs) and hybrid electric vehicles(HEVs),the high energy density Li Ni_(0.8) Co_(0.15) Al_(0.05) O_2(NCA) cathode and Si–C anode have attracted more attention.Here we report the thermal behaviors of NCA/Si–C pouch cell during the charge/discharge processes at different current densities.The total heat generations are derived from the surface temperature change during electrochemical Li+insertion/extraction in adiabatic surrounding.The reversible heat is determined by the entropic coefficients,which are related with open-circuit voltage at different temperatures; while the irreversible heat is determined by the internal resistance,which can be obtained via V–I characteristic,electrochemical impedance spectroscopy and hybrid pulse power characterization(HPPC).During the electrochemical process,the reversible heat contributes less than 10% to total heat generation; and the heat generated in charge process is less than that in discharge process.The results of thermal behaviors analyses are conducive to understanding the safety management and paving the way for building a reliable thermal model of high energy density lithium ion battery. | Ying Bai Limin Li Yu Li Guanghai Chen Huichun Zhao Zhaohua Wang Chuan Wu Hongyun Ma Xinquan Wang Hongyue Cui Jiang Zhou | 2019 | Journal of Energy Chemistry2019，28，2： | 7 |
| 7 | Structure Refinement of Cs-rich Na-Li Beryl and Analysis of Its Typomorphic Characteristics of Configurations显示文摘The tabular beryl found in Huya Country, Sichuan Province is a rare and special member among beryls. Chemical analysis reveals that the beryl is a new type of Cs-rich Na-Li beryl, and the content of alkalis (Li2O, Na2O, K2O, Rb2O, Cs2O) is up to 2.41%. The CCD system on the SMART APEX four circle single crystal diffractometer was used in this experiment to determine the structure of the sample accurately. The beryl belongs to the hexagonal system; its space group is P6/mcc. The dimensions of the unit cell are as follows: a = 0.91961(3) nm, c = 0.91969(7) nm, c/a = 1.0000, V = 0.67357 nm3, γ = 120°, α = 90°, β = 90°. The accurate atomic coordinates of alkali metal ions and other crystallographic parameters are also obtained: Z = 2, the calculated density D = 2.754 g/cm3 and final R ( I > 2 σ (I) )= 0.046 for 5597 reflections. The crystal structure was described by coordination polyhedron. Based on the data gained, a three-dimensional graph of the crystal structure of tabular beryl was made with the ATOMS 6.0 software. The refinement of crystal structure indicates that there are two main reasons for the cause of the tabular configuration: (1) The substitution of Be by Li into the tetrahedral framework weakened the stacked six-sided rings [Si6O18]12- of the tetrahedral Si; (2) Alkalis (mainly Na and Cs) are too large to substitute in four-fold or six-fold coordination within the structure and are accommodated in the vacant channel. The accommodation of these alkalis strengthened the structure of six-sided rings of the tetrahedral Si. And other alkali metal ions and free volatile molecules such as H2O and CO2 occupy variable positions in the channel. The equation of the electrovalence is Li++Na+→Be2+. According to structural and compositional differences, the monoclinic crystal of tabular beryl is considered to be a new member of the beryl group. Chemical constraints of the environment, namely, the bulk-rock chemistry and the fluid-phase composition and physical-chemical conditions during the growth of the mineral may account for these occurrences of rare elements. In addition, that Li and Be have approximate physical parameters is also the key factor for the substitution. The direction of the mineralized hydrothermal liquid and the special occurrence conditions of the beryl such as the pH, temperature and pressure are also considered to be the main causes of the configuration of the tabular beryl. | LIU Yan DENG Jun LI Guowu SHI Guanghai | 2007 | Acta Geologica Sinica(English Edition)2007，81，1： | 7 |
| 8 | Origin and Geological Significance of TTG Gneisses from the Maevatanana Greenstone Belt in North-Central Madagascar,and A Comparison with India显示文摘The Maevatanana greenstone belt in north-central Madagascar contains widespread exposures of tonalite-trondhjemite-granodiorite(TTG) gneisses,and is important for its concentrations of various metal deposits(e.g.,chromium,nickle,iron,gold).In this paper we report on the petrography,and major and trace element compositions of the TTG gneisses within the Berere Complex of the Maevatanana area,as well as LA-ICP-MS U-Pb ages and Lu-Hf isotopic compositions of zircons from the gneisses.The gneisses consist mainly of granitoid gneiss and biotite(±hornblende) plagiogneiss,and analysis of thin sections provides evidence of crushing,recrystallization,and metasomatism related to dynamic metamorphism.Samples have large variations in their major and trace element contents,with SiO_2 = 55.87-68.06 wt%,Al_2O_3 = 13.9-17.8 wt%,and Na_2O/K_2O =0.97-2.13.Geochemically,the granitoid gneisses and biotite plagiogneisses fall on a low-Al trondhjemite to granodiorite trend,while the biotite-hornblende plagiogneisses represent a high-Al tonalite TTG assemblage.Zircon U-Pb dating shows that the Berere Complex TTG gneisses formed at2.5-2.4 Ga.Most ε_(Hf(t)) values of zircons from the biotite(± hornblende) plagiogneisses are positive,while most ε_(Hf(t)) values from the granitoid gneisses are negative,suggesting a degree of crustal contamination.Two-stage Hf model ages suggest that the age of the protolith of the TTG gneisses was ca.3.4-2.6 Ga,representing a period of paleocontinent formation in the Mesoarchean.Geothermometries indicate the temperature of metamorphism of the TTG gneisses was 522-612℃.Based on these data,the protolith of the TTG gneisses is inferred to have formed during the development of a Mesoarchean paleocontinent that is now widely exposed as a TTG gneiss belt(mostly lower amphibolite facies) in the Maevatanana area,and which records a geological evolution related to the subduction of an ancient oceanic crust and the collision of microcontinents during the formation of the Rodinia supercontinent.The lithological similarity of Precambrian basement,the close ages of metamorphism within greenstone belts and the comparable distribution of metamorphic grade all show a pronounced Precambrian geology similarity between Madagascar and India,which can provide significative clues in understanding the possible Precambrian Supercontinent tectonics,and also important constraints on the correlation of the two continental fragments. | LI Peng LI Jiankang LIU Shanbao PEI Rongfu SHI Guanghai | 2017 | Acta Geologica Sinica(English Edition)2017，91，3： | 7 |
| 9 | Runout prediction and dynamic characteristic analysis of a potential submarine landslide in Liwan 3-1 gas field显示文摘A large number of submarine landslides with different scales have been identified in the canyon area of the submarine pipeline route of Liwan 3-1 gas field. There is still much chance that submarine slope failures would happen, and the following mass movement would present great risk to the submarine pipeline. In view of this, a numerical prediction method based on Eulerian-Eulerian two-phase flow model is introduced to simulate the mass movement of potential submarine landslides. The sliding soil and ambient water are respectively simulated by Herschel-Bulkley rheology model and Newtonian fluid model. The turbulence is simulated using the k-e model. Compared with both the experiment data and Bing result, the two-phase flow model shows a good accuracy, and its result is more close to the actual situation; the dynamic coupling between soil and ambient water can be effectively simulated and the phenomena of hydroplaning and head detachment can be obtained.Finally, the soil movement of a potential submarine landslide is simulated as an example, according to the seismic profile in the canyon area. The result shows that the hydroplaning occurs during the movement process. The runout distance calculated by the two-phase flow model is 877 m, which is 27.1% larger than the Bing result.However, the peak front velocity of soil is relative small, with a maximum value of 8.32 m/s. The Bing program with a simple and rapid process can be used for a preliminary evaluation, while the two-phase flow model is more appropriate for an accurate assessment. | XIU Zongxiang LIU Lejun XIE Qiuhong LI Jiagang HU Guanghai YANG Jianghui | 2015 | Acta Oceanologica Sinica2015，34，7： | 6 |
| 10 | A TiO_(2)nanotubes film with excellent antireflective and near-perfect self-cleaning performances显示文摘SiO_(2)/TiO_(2)composite films have been frequently used to realize the functions of self-cleaning and antireflection.Increasing the TiO_(2)volume ratio in SiO_(2)/TiO_(2)composite film is beneficial to enhance the self-cleaning effect,while high TiO_(2)content leads to a strong Rayleigh scattering and depresses the antireflective performance,resulting in a bottleneck problem for the dual-functional application.Here,we have achieved a high-quality TiO_(2)nanotubes film with excellent antireflective and near-perfect selfcleaning performances.Ultrasound assisted pickling method has been developed to effectively prepare the well-dispersed protonated titanate nanotubes colloid.After spin-coating and annealing treatment,glass substrate coated with double-side TiO_(2)nanotubes film has a peak transmittance of 99.2%and average transmittance of 97.4%at 400-800 nm.Ultra-high porosity of TiO_(2)nanotubes film(80%)and ultra-fine size of TiO_(2)nanotubes(8.6 nm in outer diameter)lead to excellent antireflective performance.With high UV absorptivity(80%at 254 nm)and formal quantum efficiency of stearic acid(10.9×10^(-3)),TiO_(2)nanotubes film shows near-perfect self-cleaning performance.A persistent anti-fogging ability is also presented.This study demonstrates the feasibility to fabricate pure TiO_(2)antireflective coating for glass substrate,extends application field of the classic TiO_(2)nanotubes,and sheds lights on the practical applications of high-powered TiO_(2)nanotube-based multi-functional films. | Kaibin Li Ming Li Chang Xu Zengyan Du Jiawang Chen Fengxia Zou Chongwen Zou Sichao Xu Guanghai Li | 2021 | Journal of Materials Science & Technology2021，，29： | 3 |
| 11 | PHASE STRUCTURE OF W-DOPED NANO-TiO2 PRODUCED BY SOL-GEL METHOD显示文摘With Ti(OBu)4 as precursor, and HAc as complexing agent, pure and W-doped TiO2 gelatins were prepared by a sol-gel method. During the process of gel formation, metal ions were dispersed in the porous TiO2 matrix.Then, powders of nano-TiO2 and W-doped nano-TiO2 were prepared by drying, grinding and heat treatment at different temperatures. The grain size and structure of the samples, pure TiO2 and W-doped, and treated at different temperatures,were studied by X-ray diffraction (XRD), Beckman Coulter Sorption Analysis and TEM.Results showed that, with increasing temperature, the TiO2 transformed from anatase to rutile and the grain size increased. This transformation and grain growth of TiO2 could be retarded by doping with W. | Yucheng Wu Xiaoye Hu Ting Xie Guanghai Li Lide Zhang | 2005 | China Particuology2005，3，4： | 3 |
| 12 | Feasibility study using simulation mode for offshore field SZ36-1显示文摘绥中36—1作为中海油主力注水生产、疏松砂岩稠油油田,提高采收率成为当前的主要技术方向。时移地震作为提高采收率的主要地球物理手段,使之成为主要的研究方向。本文阐述了我们利用已有的生产数据、油藏认识的可行研究,即利用动态及历史拟合的油藏模型,分析油藏可能时移地震响应,寻找时移地震响应在时空的分布特征。一方面可以分析在本地区应用时移地震技术的可行性;另一方面对第二次甚至第三次采集时移地震数据的时机进行分析。经过分析认为绥中36—1的时移地震响应除受到疏松储层的影响外,将受油藏脱气的影响。并认为生产10年后采集时移地震数据有相当的可行性。 | Zhang Jinmiao Zhao Wei Huang Xuri Wang Guanghai Liu Li | 2006 | Applied Geophysics2006，3，2： | 3 |
| 13 | Effect of dietary protein sources and storage temperatures on egg internal quality of stored shell eggs显示文摘This study was conducted to evaluate the effects of various protein sources(soybean meal, SBM; cottonseed protein, CSP; double-zero rapeseed meal, DRM) on the internal quality(Haugh unit, yolk index,albumen pH,yolk hardness and yolk springiness) of eggs when stored at either 4 or 28℃ for 28 d. A total of 288 laying hens(32 wk of age) were randomly allotted to 6 treatment groups(4 replicates per treatment) and fed diets containing SBM, CSP, or DRM individually or in combination with equal crude protein content(SBM-CSP, SBM-DRM, and CSP-DRM) as the protein ingredient(s). A 6 x 2 factorial arrangement was employed with dietary types and storage temperatures(4 and 28℃) as the main effects. After 12 wk of diet feeding, a total of 216 eggs was collected for egg internal quality determination.The results showed as follows: 1) lower egg quality was observed in the DRM group compared with the other groups when stored at 4 and 28℃ for 28 d(P < 0.05), while there was no difference in egg internal quality among the other groups. 2) The CSP diet resulted in higher yolk hardness compared with the other diets when eggs were stored at 4℃ for 28 d(P < 0.05). Lower Haugh unit was observed in the DRM and SBM-DRM groups compared with the other groups when eggs were stored for 28 d at 4℃(P < 0.05).3) Yolk breakage occurred in the DRM group and eggs could not be analyzed for egg internal quality when stored at 28℃ for 28 d. The overall results indicated that CSP or DRM as the sole dietary protein source for laying hens may adversely affect the internal quality of stored eggs as compared with the SBM diet, and half replacement of CSP combined with SBM may maintain similar egg quality to SBM diet alone for eggs stored under refrigerated conditions. | Xiaocui Wang Shugeng Wu Haijun Zhang Hongyuan Yue Guanghai Qi Jie Li | 2015 | Animal Nutrition2015，，4： | 3 |
| 14 | Dynamic Evaluation on Regional Tourism Competitiveness:Urban Agglomeration of Shandong Peninsula,Eastern China显示文摘The article establishes the appraisal index system for entire urban agglomeration and its interior cities individually,concretely including five aspects:driving forces for tourism development,the level of tourism development,tourism impacts,tourism economic connection and tourism contributions of different cities to the whole urban agglomeration.As tourism competitiveness has the characteristics of comprehensiveness,systematicness and dynamicness,the article attempts to apply the structural prediction means of system dynamics to evaluating tourism competitiveness,aiming to provide some research methods and analysis ideas for tourism competitiveness measurement and trends analysis in urban agglomeration.Taking Shandong Peninsula urban agglomeration as the study area,the article simulates and analyzes the tourism competitiveness trend of the whole region and its interior cities from 2005 to 2020,and the result reflects that integrated development and regional combination of tourism are important means to upgrade tourism competitiveness in this region. | Li Xue Dong Suocheng Jin Xianfeng Zhang Guanghai | 2009 | Chinese Journal of Population,Resources and Environment2009，7，3： | 2 |
| 15 | Image retrieval based on micro-structure descriptor 显示文摘 | GUANGHAI LIU ZUOYONG LI LEI ZHANG | 2011 | Pattern Recognition2011，44，9： | 1 |
| 16 | Statistical thresholding method for infrared images显示文摘 | Li Zuoyong Liu Chuancai Liu Guanghai | 2011 | Pattern Analysis and Applications2011，14，： | 1 |
| 17 | Precipitation behavior of grain boundary M 23 C 6 and its effect on tensile properties of Ni–Cr–W based superalloy显示文摘 | Rui Hu Guanghai Bai Jinshan Li Jingqing Zhang Tiebang Zhang Hengzhi Fu | 2012 | Materials Science & Engineering A2012，，： | 1 |
| 18 | Enhancement of Molar Heat Capacity of Nanostructured Al2O3显示文摘 | Lan Wang Zhicheng Tan Shuanghe Meng Dongbai Liang Guanghai Li | 2001 | Journal of Nanoparticle Research (-)2001，，5： | 1 |
| 19 | Effect of temperature on tensile behavior of Ni–Cr–W based superalloy显示文摘 | Guanghai Bai Jinshan Li Rui Hu Zengwu Tang Xiangyi Xue Hengzhi Fu | 2010 | Materials Science & Engineering A2010，，4： | 1 |
| 20 | VO_2(B) Nanosheets as a Cathode Material for Li-ion Battery显示文摘VO_2(B) nanosheets were prepared by a liquid-phase exfoliation from VO_2(B) bulk.The lithium storage properties of VO_2(B) nanosheets as capacity cathode materials for rechargeable lithium secondary batteries were investigated.It was found that the nanosheets with the thickness of several nanometers and width of tens of nanometer had a preferential growth direction along[001]orientation.By comparing with VO_2(B) bulk,the VO_2(B) nanosheets showed a higher initial discharge capacity and a slower capacity fading rate.The reasons for these phenomena were discussed and analyzed. | Qiang Wang Jing Pan Ming Li Yuanyuan Luo Hao Wu Li Zhong Guanghai Li | 2015 | Journal of Materials Science & Technology2015，31，6： | 1 |
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