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| 1 | Spatial patterns and driving forces of land use change in China during the early 21st century显示文摘Land use and land cover change as the core of coupled human-environment systems has become a potential field of land change science (LCS) in the study of global environmental change. Based on remotely sensed data of land use change with a spatial resolution of 1 km × 1 km on national scale among every 5 years, this paper designed a new dynamic regionalization according to the comprehensive characteristics of land use change including regional differentiation, physical, economic, and macro-policy factors as well. Spatial pattern of land use change and its driving forces were investigated in China in the early 21st century. To sum up, land use change pattern of this period was characterized by rapid changes in the whole country. Over the agricultural zones, e.g., Huang-Huai-Hai Plain, the southeast coastal areas and Sichuan Basin, a great proportion of fine arable land were engrossed owing to considerable expansion of the built-up and residential areas, resulting in decrease of paddy land area in southern China. The development of oasis agriculture in Northwest China and the reclamation in Northeast China led to a slight increase in arable land area in northern China. Due to the 'Grain for Green' policy, forest area was significantly increased in the middle and western developing regions, where the vegetation coverage was substantially enlarged, likewise. This paper argued the main driving forces as the implementation of the strategy on land use and regional development, such as policies of 'Western Development', 'Revitalization of Northeast', coupled with rapidly economic development during this period. | LIU Jiyuan ZHANG Zengxiang XU Xinliang KUANG Wenhui ZHOU Wancun ZHANG Shuwen LI Rendong YAN Changzhen YU Dongsheng WU Shixin JIANG Nan | 2010 | Journal of Geographical Sciences2010，20，4： | 154 |
| 2 | Isolation and characterization of H7N9 viruses from live poultry markets--Implication of the source of current H7N9 infection in humans显示文摘On March 31, 2013, the National Health and Family Planning Commission announced that human infections with a previously undescribed influenza A (H7N9) virus had occurred in Shanghai and Anhui Province, China. To investigate the possible origins of the H7N9 viruses causing these human infections, we collected 970 samples, including drinking water, soil, and cloacal and tracheal swabs of poultry from live poultry markets and poultry farms in Shanghai and Anhui Province. Twenty samples were positive for the H7N9 influenza virus. Notably, all 20 viruses were isolated from samples collected from live poultry markets in Shanghai. Phylogenetic analyses showed that the six internal genes of these novel human H7N9 viruses were derived from avian H9N2 viruses, but the ancestor of their HA and NA genes is uncertain. When we examined the phylogenetic relationship between the H7N9 isolates from live poultry markets and the viruses that caused the human infections, we found that they shared high homology across all eight gene segments. We thus identified the direct avian origin of the H7N9 influenza viruses that caused the human infections. Importantly, we observed that the H7N9 viruses isolated from humans had acquired critical mutations that made them more 'human-like'. It is therefore imperative to take strong measures to control the spread of H7N9 viruses in birds and humans to prevent further threats to human health. | SHI JianZhong DENG GuoHua LIU PeiHong ZHOU JinPing GUAN LiZheng LI WenHui LI XuYong GUO Jing WANG GuoJun FAN Jun WANG JinLiang LI YuanYuan JIANG YongPing LIU LiLing TIAN GuoBin LI ChengJun CHEN HuaLan | 2013 | Chinese Science Bulletin2013，58，16： | 85 |
| 3 | Spatiotemporal characteristics, patterns, and causes of land-use changes in China since the late 1980s显示文摘Land-use/land-cover 变化(LUCC ) 有连接到人和自然相互作用。瓷器 Land-Use/cover 数据集(CLUD ) 从 1980 年代末在 5 年的间隔定期被更新到 2010,与基于 Landsat TMETM+ 图象的标准过程。陆地使用动态区域化方法被建议分析主要陆地使用变换。在国家规模的陆地使用变化的空间与时间的特征,差别,和原因然后被检验。主要调查结果如下被总结。越过中国的陆地使用变化(LUC ) 在最后 20 年(19902010 ) 里在空间、时间的特征显示了一个重要变化。农田变化的区域在南方减少了并且在北方,而是仍然是的全部的区域增加了几乎未改变。回收农田从东北被转移到西北。布满建筑物陆地很快膨胀了,主要在东方被散布,并且逐渐地展开到中央、西方的中国。树林首先减少了,然后增加但是荒芜的区域是反面。草地继续减少。在中国的 LUC 的不同空间模式被发现在之间迟了第 20 世纪并且早第 21 世纪。原版 13 个 LUC 地区在一些地区被边界的变化由 15 个单位代替。包括的这些变化(1 ) 的主要空间特征加速的扩大布满建筑物在 Huang-Huai-Hai 区域,东南的沿海的区域,长江的中流区域,和四川盆登陆;(2 ) 从东北中国和东方内部蒙古在北方转移了陆地开垦到绿洲在西北中国的农业区域;(3 ) 从在到稻的东北中国的喂雨的农田的连续转变回答;并且(4 ) 为在内部蒙古,黄土高原,和西南的多山的区域的南部的农业牧剧的交错群落的格林工程的谷物的有效性。在最后二十年,尽管在北方的气候变化在农田影响了变化,政策规定和经济驱动力仍然是越过中国的 LUC 的主要原因。在第 21 世纪的第一十年期间,在陆地使用模式驾驶了变化的人为的因素从单程的陆地开发转移了强调到开发和保存。动态区域化方法被用来在单位的 zoning 边界,地区的内部特征,和生长和减少的空间模式分析变化。结果揭示了变化过程的模式,也就是 LUC 的过程和在在不同阶段的特征的地区性的差别。地区的生长和减少在这动态 LUC zoning,在统一边界的变化,和在前者和后者十年之间的变化紧张的特征期间被检验。在为在不同类型和陆地使用的不同区域的变化的陆地使用和原因的模式和过程之间的其他的转变的模式被探索。 | LIU Jiyuan KUANG Wenhui ZHANG Zengxiang XU Xinliang QIN Yuanwei NING Jia ZHOU Wancun ZHANG Shuwen LI Rendong YAN Changzhe WU Shixin SHI Xuezheng JIANG Nan YU Dongsheng PAN Xianzhang CHI Wenfeng | 2014 | Journal of Geographical Sciences2014，24，2： | 245 |
| 4 | Superhydrophobic coatings for corrosion protection of magnesium alloys显示文摘Magnesium(Mg)alloys show great potential to be extensively applied in practice owing to their superior properties,while the poor corrosion resistance does undoubtedly restrict their applications.Superhydrophobic coatings with good repellency to corrosive solutions can significantly decrease the interaction between the corrosive species and the substrate,so that they are receiving a lot of attention to improve the corrosion resistance of Mg alloys.Various strategies have been introduced to develop a superhydrophobic coating on Mg alloys,which were reviewed to elucidate the current research status to provide a clue or thinking for beginning researchers.Further,the existing issues of superhydrophobic coating were discussed,especially for their real applications in practice,mainly owing to their poor mechanical stability.Based on the existing issues,the future study was discussed to improve the stability of hierarchical structures and entrapped air pockets,impart the superhydrophobic coating self-healing property to repair the damaged area during service,provide double protection by incorporation of corrosion inhibitors,or even introduce slippery liquid-infused porous surfaces with lubricant layer to provide better corrosion protection for Mg alloys. | Wenhui Yao Liang Wu Guangsheng Huang Bin Jiang Andrej Atrens Fusheng Pan | 2020 | Journal of Materials Science & Technology2020，52，17： | 15 |
| 5 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 6 | High-performance silicon−graphene hybrid plasmonic waveguide photodetectors beyond 1.55μm显示文摘Graphene has attracted much attention for the realization of high-speed photodetection for silicon photonics over a wide wavelength range.However,the reported fast graphene photodetectors mainly operate in the 1.55μm wavelength band.In this work,we propose and realize high-performance waveguide photodetectors based on bolometric/photoconductive effects by introducing an ultrathin wide silicon−graphene hybrid plasmonic waveguide,which enables efficient light absorption in graphene at 1.55μm and beyond.When operating at 2μm,the present photodetector has a responsivity of ~70 mA/W and a setup-limited 3 dB bandwidth of >20 GHz.When operating at 1.55μm,the present photodetector also works very well with a broad 3 dB bandwidth of >40 GHz(setup-limited)and a high responsivity of ~0.4 A/W even with a low bias voltage of−0.3 V.This work paves the way for achieving highresponsivity and high-speed silicon-graphene waveguide photodetection in the near/mid-infrared ranges,which has applications in optical communications,nonlinear photonics,and on-chip sensing. | Jingshu Guo Jiang Li Chaoyue Liu Yanlong Yin Wenhui Wang Zhenhua Ni Zhilei Fu Hui Yu Yang Xu Yaocheng Shi Yungui Ma Shiming Gao Limin Tong Daoxin Dai | 2020 | Light(Science & Applications)2020，9，1： | 10 |
| 7 | High-Resolution Genome-wide Association Study Identifies Genomic Regions and Candidate Genes for Important Agronomic Traits in Wheat显示文摘Wheat(Triticum aestivum)is a major staple food crop worldwide.Genetic dissection of important agronomic traits is essential for continuous improvement of wheat yield to meet the demand of the world's growing population.We conducted a large-scale genome-wide association study(GWAS)using a panel of 768 wheat cultivars that were genotyped with 327609 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative trait loci(QTLs)for 12 traits under 7 environments.Among them,273 QTLs were delimited to≤1.0-Mb intervals and 7 of them are either known genes(Rht-D,Vrn-B1,and Vrn-D1)that have been cloned or known QTLs(TaGA2ox8,APO1,TaSus1-7B,and Rht12)that were previously mapped.Eight putative candidate genes were identified for three QTLs that enhance spike seed setting and grain size using gene expression data and were validated in three bi-parental populations.Protein sequence analysis identified 33 putative wheat orthologs that have high identity with rice genes in QTLs affecting similar traits.Large r^2 values for additive effects observed among the QTLs for most traits indicated that the phenotypes of these identified QTLs were highly predictable.Results from this study demonstrated that significantly increasing GWAS population size and marker density greatly improves detection and identification of candidate genes underlying a QTL,solidifying the foundation for large-scale QTL fine mapping,candidate gene validation,and developing functional markers for genomics-based breeding in wheat. | Yunlong Pang Chunxia Liu Danfeng Wang Paul St.Amand Amy Bernardo Wenhui Li Fang He Linzhi Li Liming Wang Xiufang Yuan Lei Dong Yu Su Huirui Zhang Meng Zhao Yunlong Liangi Hongze Jia Xitong Shen Yue Lu Hongming Jiang Yuye Wu Anfei Li Honggang Wang Lingrang Kong Guihua Bai Shubing Liu | 2020 | Molecular Plant2020，13，9： | 8 |
| 8 | Micro-arc oxidation of magnesium alloys:A review显示文摘Magnesium(Mg)and its alloys present great potential to be extensively applied in different applications.However,the relatively poor resistance to corrosion and wear significantly restricts their applications in practice.As one of strategies of surface treatment,micro-arc oxidation(MAO)process attracts a lot of attention,since it does not use neither expensive equipment,nor complicated manipulation.This review systematically discusses MAO mechanism and some typical models,which still need to be further developed to provide a better understanding and guide for future researchers.Subsequently,main influencing factors of MAO process are analyzed in detail.Further,some popular applications of MAO coatings are respectively reviewed,including biomedical application,decoration,thermal control,corrosion and wear resistance,and industrial applications in practice.The existing issues and future perspectives are finally discussed to further accelerate extensive applications of Mg alloys. | Wenhui Yao Liang Wu Jingfeng Wang Bin Jiang Dingfei Zhang Maria Serdechnova Tatsiana Shulha Carsten Blawert Mikhail L.Zheludkevich Fusheng Pan | 2022 | Journal of Materials Science & Technology2022，，23： | 8 |
| 9 | Recent Developments in Fiber Optic Spectral White-Light Interferometry显示文摘Recent developments in spectral white-light interferometry(WLI)are reviewed.Firstly,the techniques for obtaining optical spectrum are introduced.Secondly,some novel measurement techniques are reviewed,including the improved peak-to-peak WLI,improved wavelength-tracking WLI,Fourier transform WLI,and 3×3 coupler based WLI.Furthermore,a hybrid measurement for the intensity-type sensors,interferometric sensors,and fiber Bragg grating sensors is achieved.It is shown that these developments have assisted in the progress of WLI. | Yi JIANG Wenhui DING | 2011 | Photonic Sensors2011，1，1： | 6 |
| 10 | CRA-40/Atmosphere—The First-Generation Chinese Atmospheric Reanalysis(1979–2018):System Description and Performance Evaluation显示文摘Atmospheric reanalysis reproduces the past atmospheric conditions through assimilation of historical meteorological observations with fixed version of a numerical weather prediction(NWP)model and data assimilation(DA)system.It is widely used in weather,climate,and even business-related research and applications.This paper reports the development of CMA’s first-generation global atmospheric reanalysis(RA)covering 1979–2018(CRA-40;CRA refers to CMA-RA).CRA-40 is produced by using the Global Spectral Model(GSM)/Gridpoint Statistical Interpolation(GSI)at a 6-h time interval and a TL574 spectral(34-km)resolution with the model top at 0.27 hPa.A large number of reprocessed satellite data and widely collected conventional observations were assimilated during the reanalyzing process,including the reprocessed atmospheric motion vector(AMV)products from FY-2C/D/E/G satellites,dense conventional observations(at about 120 radiosonde and 2400 synoptic stations)over China,as well as MWHS-2 and GNSS-RO observations from FY-3C.The reanalysis fitting to observations is improved over time,especially for surface pressure with root-mean-square error reduced from 1.05 hPa in 1979 to 0.8 hPa,and for upper air temperature from 1.65 K in 1979 to 1.35 K,in 2018.The patterns of global analysis increments for temperature,specific humidity,and zonal wind are consistent with the changes in the observing system.Near surface temperature from the model’s 6-h forecast reflects the global warming trend reasonably.The CRA-40 precipitation pattern matches well with those of GPCP and other reanalyses.CRA-40 also successfully captures the QBO and its vertical and temporal development,hemispherical atmospheric circulation change,and moisture transport by the East Asian summer monsoon.CRA is now operationally running in near real time as a climate data assimilation system in CMA. | Zhiquan LIU Lipeng JIANG Chunxiang SHI Tao ZHANG Zijiang ZHOU Jie LIAO Shuang YAO Jingwei LIU Minyan WANG Huiying WANG Xiao LIANG Zhisen ZHANG Yan YAO Ting ZHU Zhe CHEN Wenhui XU Lijuan CAO Hui JIANG Kaixi HU | 2023 | Journal of Meteorological Research2023，37，1： | 4 |
| 11 | The IAA-and ABA-responsive transcription factor CgMYB58 upregulates lignin biosynthesis and triggers juice sac granulation in pummelo显示文摘In citrus,lignin overaccumulation in the juice sac results in granulation and an unpleasant fruit texture and taste.By integrating metabolic phenotyping and transcriptomic analyses,we found 702 differentially expressed genes(DEGs),including 24 transcription factors(TFs),to be significantly correlated with lignin content.CgMYB58 was further identified as a critical R2R3 MYB TF involved in lignin overaccumulation owing to its high transcript levels in Huanong Red-fleshed pummelo(HR,Citrus grandis)fruits.Transient expression of CgMYB58 led to an increase in the lignin content in the pummelo fruit mesocarp,whereas its stable overexpression significantly promoted lignin accumulation and upregulated 19 lignin biosynthetic genes.Among these genes,CgPAL1,CgPAL2,Cg4CL1,and CgC3H were directly modulated by CgMYB58 through interaction with their promoter regions.Moreover,we showed that juice sac granulation in pummelo fruits could be affected by indole-3-acetic acid(IAA)and abscisic acid(ABA)treatments.In HR pummelo,ABA significantly accelerated this granulation,whereas IAA effectively inhibited this process.Taken together,these results provide novel insight into the lignin accumulation mechanism in citrus fruits.We also revealed the theoretical basis via exogenous IAA application,which repressed the expression of CgMYB58 and its target genes,thus alleviating juice sac granulation in orchards. | Meiyan Shi Xiao Liu Haipeng Zhang Zhenyu He Hongbin Yang Jiajing Chen Jia Feng Wenhui Yang Youwu Jiang Jia-Long Yao Cecilia Hong Deng Juan Xu | 2020 | Horticulture Research2020，7，1： | 4 |
| 12 | Design and construction of HYSY981显示文摘This paper focuses on the independent design and construction of HYSY981. HYSY981,which China National Offshore Oil Corporation(CNOOC) possesses its intellectual property right,is brought forward by advanced research,concept design and combined basic design. The key technologies are the researches concerning global design,system integration,platform positioning,global performance analysis,structural strength and fatigue analysis,environment effect assessment of South China Sea,basin test and tunnel test,and construction technology of platform. Core technology of design and construction for the 6th deep water semi-submersible rig is held. Independent detail design and construction are also accomplished. These have improved technology of key equipment for China offshore oil exploitation. | Xie Bin Lin Yaosheng Su Jing Zeng Hengyi Xie Wenhui Jiang Zhe | 2011 | Engineering Sciences2011，9，4： | 4 |
| 13 | Development of metal-organic framework(MOF) decorated graphene oxide/Mg Al-layered double hydroxide coating via microstructural optimization for anti-corrosion micro-arc oxidation coatings of magnesium alloy显示文摘An efcient and simple in-situ growth strategy has been discovered for the preparation of highly reproducible and continuous symbiotic ZIF-8-based anticorrosion coating by using graphene oxide(GO)/Mg AlNO3layered double hydroxides(G/LDHs) buffer layer as a new type of connecting carrier based on micro-arc oxide(MAO) coating of AZ31 magnesium alloy. The components of ZIF-8 were adsorbed and bounded to the surface of the G/LDHs buffer layer-modified substrates to promote the nucleation of ZIF-8,thus growing a phase-pure, uniform, and good symbiosis ZIF-8 membrane. ZIF-8 particles with different growth times compensate for the grain boundary defects of the G/LDHs coating precursor buffer layer to different degrees. The prepared ZIF-8-based coating has excellent stability and corrosion resistance. The results demonstrate that the G/LDHs buffer layer provides a new channel for the MOF-modified MAO substrate of AZ31 magnesium alloy. It also proves that it is feasible to build high-performance anticorrosive coatings with MOF materials. | Yanning Chen Liang Wu Wenhui Yao Jiahao Wu Jianpeng Xiang Xiaowei Dai Tao Wu Yuan Yuan Jingfeng Wang Bin Jiang Fusheng Pan | 2022 | Journal of Materials Science & Technology2022，，35： | 3 |
| 14 | Ultrasensitive graphene-Si position-sensitive detector for motion tracking显示文摘Motion tracking has attracted great attention in the fields of real-time tracking,nanorobotics,and targeted therapy.For achieving more accurate motion tracking,the highly sensitive position-sensitive detector(PSD)is desirable.Here,we demonstrate a meliorated PSD based on graphene-Si heterojunction for motion tracking.The position sensitivity of PSD was improved by employing surface engineering of graphene.Through modulating the transport property of graphene,nearly 20-fold increase of sensitivity was achieved under weak light,and at the same time,the detection limit power was reduced to^2 nW.A motion tracking system was developed based on the improved PSD,and human arm swing was tracked,which demonstrated high sensitivity and real-time tracking capabilities of the PSD.In addition,the PSD can support up to^10 kHz high-frequency tracking.This work provides a new strategy for improving the performance of PSD,and promotes the development of two-dimensional materials in novel optoelectronic devices. | Wenhui Wang Kaiyang Liu Jie Jiang Ruxia Du Litao Sun Wei Chen Junpeng Lu Zhenhua Ni | 2020 | InfoMat2020，2，4： | 3 |
| 15 | Improving the mechanical property of dissimilar Al/Mg hybrid friction stir welding joint by PIO-ANN显示文摘Ultrasonic-stationary shoulder assisted friction stir welding(U-SSFSW)is a novel hybrid welding technique,which reveals promising prospect in joining Al/Mg dissimilar alloys.A thorough understanding of U-SSFSW process is imperative for the further application of this technique.Pigeon-inspired optimization(PIO)is a swarm intelligent optimization algorithm and is proposed in mathematical modeling and process optimization by artificial intelligence.In this study,PIO optimized artificial neural network(PIOANN)was firstly established to acquire the relationships between the inputs and output of the Al/Mg welding process by U-SSFSW technique.A reliable PIO-ANN was achieved and the joint with a tensile strength of 161 MPa was acquired under the PIO optimized parameters.This tensile strength is higher than any ever-reported results with the similar welding condition.The joint formation,microstructure,microhardness and fracture behaviors were systemically investigated based on the reported studies and the confirmation experiment of this study to explore the enhancing mechanism of U-SSFSW Al/Mg joint. | Wei Hu Zhongwei Ma Shude Ji Qi Song Mingfei Chen Wenhui Jiang | 2020 | Journal of Materials Science & Technology2020，52，18： | 3 |
| 16 | Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19显示文摘Coronavirus disease 2019(COVID-19),which is caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2),has spread around the world.However,approaches to distinguish COVID-19 from pneumonia caused by other pathogens have not yet been reported.We retrospectively analyzed the clinical data of 97 children with probable COVID-19.A total of 13(13.4%)patients were confirmed positive for SARS-CoV-2 infection by nucleic acid RT-PCR testing,and 41(42.3%)patients were found to be infected with other pathogens.Notably,no pathogen was detected in 43(44.3%)patients.Among all patients,25(25.8%)had familial cluster exposure history,and 52(53.6%)had one or more coexisting conditions.Fifteen(15.5%)patients were admitted or transferred to the PICU.In the 11 confirmed COVID-19 cases,5(45.5%)and 7(63.6%)were positive for IgM and IgG against SARS-CoV-2,respectively.In 22 patients with suspected COVID-19,1(4.5%)was positive for IgG but negative for IgM.The most frequently detected pathogen was Mycoplasma pneumonia(29,29.9%).One patient with confirmed COVID-19 died.Our results strongly indicated that the detection of asymptomatic COVID-19 or coexisting conditions must be strengthened in pediatric patients.These cases may be difficult to diagnose as COVID-19 unless etiologic analysis is conducted.A serologic test can be a useful adjunctive diagnostic tool in cases where SARS-CoV-2 infection is highly suspected but the nucleic acid test is negative. | Xiaofang Cai Hanlan Jiang Simin Zhang Shengying Xia Wenhui Du Yaoling Ma Tao Yu Wenbin Li | 2020 | Frontiers of Medicine2020，14，6： | 2 |
| 17 | Variation on leaching behavior of caustic compounds in bauxite residue during dealkalization process显示文摘Bauxite residue,a byproduct of alumina manufacture,is a serious environmental pollutant due to its high leaching contents of metals and caustic compounds.Four typical anions of CO3^2-,HCO3^-,Al(OH)4^- and OH-(represented caustic compounds) and metal ions(As,B,Mo and V) were selected to assess their leaching behavior under dealkalization process with different conditions including liquid/solid ratio(L/S ratio),temperature and leaching time.The results revealed that washing process could remove the soluble composition in bauxite residue effectively.The leaching concentrations of typical anions in bauxite residue decreased as follows:c(CO3^2-)> c(HCO3^-)> c[Al(OH)4-]> c(OH-).L/S ratio had a more significant effect on leaching behavior of OH-,whilst the leaching concentration of Al(OH)4-varied larger underleaching temperature and time treatment.Under the optimal leaching,the total alkaline,soluble Na concentrations,exchangeable Ca concentrations were 79.52,68.93,and 136.0 mmol/L,respectively,whilst the soluble and exchangeable content of As,B,Mo and V in bauxite residue changed slightly.However,it should be noted that water leaching has released metal ions such as As,B,Mo and V in bauxite residue to the surrounding environment.The semiquantitative analysis of XRD revealed that water leaching increased the content of gismondine from 2.4% to 6.4%.The SEM images demonstrated the dissolution of caustic compounds on bauxite residue surface.The correlation analysis indicated that CO3^2- and HCO3^- could effectively reflect the alkalinity of bauxite residue,and may be regarded as critical de alkalization indicators to evaluate alkalinity removal in bauxite residue. | Yujun Wu Meng Li Feng Zhu William Hartley Jiaxin Liao Wenhui An Shengguo Xue Jun Jiang | 2020 | Journal of Environmental Sciences2020，32，6： | 2 |
| 18 | Electrochemical co-deposition of reduced graphene oxide-gold nanocomposite on an ITO substrate and its application in the detection of dopamine显示文摘The simultaneous deposition of rGO and gold nano structures has been achieved by electrodeposition from mixed solutions containing graphene oxide(GO)and a gold precursor.Scanning electron microscope(SEM),Raman spectroscopy and atomic force microscopy(AFM)have been employed to reveal the morphology,uniformity and practical stability of the nanocomposite films on the indium tin oxide(ITO)substrate.The AFM data showed heights of tens of nanometers of the nanocomposite,suggesting that multilayers of rGO with gold nanoparticles had been formed as a result of the electrochemical co-deposition.Differential pulse voltammetry(DPV),as a widely used analytical technique,has been carried out on the rGO-Au/ITO electrode for the quantitative detection of dopamine(DA).The detection limit(S/N=3)for the determination of DA was evaluated as 0.6μM. | Chaoyi Jiang Xiangzhou Zeng Bijun Wu Qiao Zeng Wenhui Pang Jing Tang | 2017 | Science China Chemistry2017，60，1： | 2 |
| 19 | Effects of dietary fiber content and different fiber-rich ingredients on endogenous loss of fat and fatty acids in growing pigs显示文摘Background: Determination of the endogenous loss of fat(ELF) is used to adjust for the estimation of true total tract digestibility(TTTD) of fat in diets and ingredients.Any factor which affected ELF may further affect the digestibility of fat,including sources and concentrations of fat and fiber in the diet.There are some reports of determining the ELF using regression methods based on different levels of fat intake,while reports on effects of dietary fiber content and different fiber-rich ingredients in pig diets on ELF are very limited.Therefore,the objective of this study was to determine the effects of dietary fiber content and different fiber-rich ingredients on endogenous losses of fat and fatty acids at the end of ileum and throughout the entire intestinal tract in growing pigs.Methods: In Exp.1,the effect of fiber content on endogenous loss of fat was determined using six growing pigs(Duroc × Landrace × Yorkshire;27.6 ± 2.4 kg),fitted with a T-cannula at the end of ileum.The experimental design was a 6 × 6 complete Latin square design with six periods of feeding and six diets.The six experimental fat-free diets were formulated to include graded levels of neutral detergent fiber(NDF)(0,40,80,120,160 and 200 g/kg) and soybean hull(SH) was the only fiber source,providing 0,75,150,225,300 and 375 g/kg,respectively.Chromic oxide was included at4 g/kg in all diets as an indigestible marker.In Exp.2,six crossbred growing barrows(27.6 ± 1.6 kg) were used and the experimental design was the same as for Exp.1.The six fat-free diets were formulated to include six common fiber-rich ingredients and the concentration of NDF was 100 g/kg.The six fiber-rich ingredients were defatted rice bran(DRB),sugar beet pulp(SBP),rice hull(RH),corn germ meal(CGM),SH and wheat bran(WB) and they were fed at represented250,270,145,250,170 and 280 g/kg in the diet,respectively.Results: In Exp.1,the endogenous loss of fatty acids profile did not change as dietary NDF increased in growing pigs.The endogenous losses of fat,C16:0,C18:0,C18:1,C18:2,total unsaturated fatty acids(UFA) and total saturated fatty acids(SFA) in growing pigs at the end of ileum and throughout the entire intestinal tract increased linearly as NDF content of diets increased.The endogenous losses of fat,as well as C16:0 and C18:0 throughout the entire intestinal tract also increased quadratically as NDF content of diets increased.The ELF increased from 0.71 to 3.14 g/kg of dry matter intake(DMI) and 0.56 to 8.21 g/kg DMI at the end of ileum and throughout the entire intestinal tract in growing pigs,respectively.The ELF occurred in the hindgut except for the growing pigs fed 0 and 4% NDF in their diets.The endogenous losses of C16:0 and UFA occurred primarily in the upper regions of the gut and the greatest endogenous losses of C18:0 occurred in the hindgut.The endogenous losses of fat,individual SFA and total SFA throughout the entire intestinal tract were much greater than that at the end of ileum.However,the endogenous losses of individual UFA and total UFA were less throughout the intestinal tract than at the end of ileum.In Exp.2,the endogenous losses of fat at the end of ileum were greater in growing pigs fed CGM or WB diets.The endogenous loss of fatty acids profile changed to a slight degree at the end of ileum that the endogenous loss of UFA(particularly C18:1 and C18:2) in growing pigs fed CGM or WB diets were greater(P < 0.01) than that for the other four diets.The greatest(P < 0.01) endogenous loss of SFA(particularly C18:0) was in growing pigs fed the RH diet.The endogenous losses of fat,C16:0,C18:0 and SFA over the entire intestinal tract were much greater in growing pigs fed CGM or WB diets,whereas the lowest values were in growing pigs fed DRB diet.The ELF at the end of ileum in growing pigs fed CGM or WB diets were 3.50 or 4.17 g/kg DMI,respectively,and the ELF over the entire intestinal tract was 7.23 or 7.38 g/kg DMI.The contribution in percentage of ELF in the upper gut was greater than that in the hindgut of growing pigs fed DRB and RH diets,while the ELF in the upper gut and hindgut were equal in growing pigs fed SBP,CGM and WB diets.On the whole,the endogenous losses of C18:1 and C18:2 throughout the entire intestinal tract in growing pigs fed the six fiber-rich ingredients diets were less than losses at the end of ileum,whereas the endogenous loss of fat,C16:0,C18:0 and SFA were greater throughout the intestinal tract than at the end of ileum.Conclusion: The profile of loss in endogenous fatty acids did not change as dietary NDF increased in growing pigs and the endogenous losses of fatty acids(C16:0,C18:0,C18:1 and C18:2) fat,UFA and SFA increased linearly as NDF content increased in the diets of pigs.The endogenous losses of fat or fatty acids at the end of ileum were greater in growing pigs fed RH,CGM or WB diets.The endogenous losses of fat,fatty acids(C16:0 and C18:0) and SFA were greater over the entire intestinal tract in pigs fed CGM or WB diet,while these values were the lowest in growing pigs fed the DRB diet.The contribution in percentage losses of fat in the upper gut were greater than in the hindgut of growing pigs fed DRB and RH diets,while the contribution of losses of fat in the upper gut and hindgut were equal in growing pigs fed SBP,CGM and WB diets.In addition,the endogenous loss of individual or total UFA was less over the entire intestinal tract of growing pigs fed fiber diets than that at the end of ileum,and the greatest endogenous losses of fat,individual or total SFA were over the entire intestinal tract.Therefore,differences in fiber content and the nature of fiber-rich ingredients in diets of pigs have different effects to the endogenous losses of fat or fatty acids.Considering the requirement of fat or fatty acids of pigs,careful attention must be paid that the endogenous losses of fat and fatty acids when fiber ingredients are used in diets of pigs. | Yifan Chen Zhenyu Wang Jian Ding Dongxu Ming Wenhui Wang Zhaoning Jiang Ling Liu Fenglai Wang | 2019 | Journal of Animal Science and Biotechnology2019，10，3： | 2 |
| 20 | Decreased expression of protease-activated receptor 4 in human gastric cancer显示文摘 | Yong Zhang Guoyu Yu Ping Jiang Yang Xiang Wenliang Li Wenhui Lee Yun Zhang | 2011 | International Journal of Biochemistry and Cell Biology2011，，9： | 2 |
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