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| 1 | The discovery of Palaeoproterozoic volcanic rocks in the Bulunkuoler Group from the Tianshuihai Massif in Xinjiang of Northwest China and its geological significance显示文摘In the Dabudaer region of the Tianshuihai Massif (Xinjiang, Northwest China), metavolcanic rocks within the mainly meta-sedimentary Bulunkuoler Group are basalt, basaltic andesite, and rhyolite. In situ zircon U-Pb LA-ICP-MS dating on rhyolite magmatic zircons yielded an age of 2481±14 Ma, interpreted as the eruption age of the Bulunkuoler Group volcanic rocks. The basalt and basaltic andesite are low-Al tholeiite series and the rhyolite is low-Al calc-alkaline series. All of rocks are charac-terized by enrichment of LREE and LILE (Rb, Th and Ba), depletion of P, Nb, Ta and Ti, and absence of Eu anomalies. The εNd(t) of basalts ranges from 3.14 to 4.88 indicating a depleted mantle source. The trace element signatures show that these magmas experienced intense crustal contamination during their ascent. Direct evidence for crustal contamination is the xenocrystic zircons in the ryholite, with ages back to ca. 3300 Ma. The primitive-mantle normalized and Zr/Y-Zr diagrams for the basic volcanic rocks show that they formed in an intra-continental tectonic setting. Combined with the previous studies and compared with North China Craton Neoarchean basic volcanic rocks, it is supposed that the Bulunkuoler Group volcanic rocks reflect the Palaeoproterozoic mantle magma underplating and interaction with felsic crust. | JI WenHua LI RongShe CHEN ShouJian HE ShiPing ZHAO ZhenMing BIAN XiaoWei ZHU HaiPing CUI JiGang REN JuanGang | 2011 | Science China Earth Sciences2011，54，1： | 22 |
| 2 | Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1显示文摘Ferroptosis is a form of regulated cell death, characterized by excessive membrane lipid peroxidation in an iron-and ROS-dependent manner. Celastrol, a natural bioactive triterpenoid extracted from Tripterygium wilfordii, shows effective anti-fibrotic and anti-inflammatory activities in multiple hepatic diseases. However, the exact molecular mechanisms of action and the direct protein targets of celastrol in the treatment of liver fibrosis remain largely elusive. Here, we discover that celastrol exerts anti-fibrotic effects via promoting the production of reactive oxygen species(ROS) and inducing ferroptosis in activated hepatic stellate cells(HSCs). By using activity-based protein profiling(ABPP) in combination with bio-orthogonal click chemistry reaction and cellular thermal shift assay(CETSA), we show that celastrol directly binds to peroxiredoxins(PRDXs), including PRDX1, PRDX2, PRDX4 and PRDX6,through the active cysteine sites, and inhibits their anti-oxidant activities. Celastrol also targets to heme oxygenase 1(HO-1) and upregulates its expression in activated-HSCs. Knockdown of PRDX1, PRDX2,PRDX4, PRDX6 or HO-1 in HSCs, to varying extent, elevated cellular ROS levels and induced ferroptosis. Taken together, our findings reveal the direct protein targets and molecular mechanisms via which celastrol ameliorates hepatic fibrosis, thus supporting the further development of celastrol as a promising therapeutic agent for liver fibrosis. | Piao Luo Dandan Liu Qian Zhang Fan Yang Yin-Kwan Wong Fei Xia Junzhe Zhang Jiayun Chen Ya Tian Chuanbin Yang Lingyun Dai Han-Ming Shen Jigang Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 14 |
| 3 | Deformation mechanism and stability control of roadway along a fault subjected to mining显示文摘It is difficult to maintain the roadway around a fault because of the fractured surroundings,complex stress environment,and large and intense deformation in the mining process.Based on a tailgate of panel S2205 in Tunliu colliery,in Shanxi province,China,we investigated the evolution of stress and displacement of rocks surrounding the roadway during the drivage and mining period using theoretical analysis,numerical simulation and field trial methods.We analyzed the deformation and failure mechanisms of the tailgate near a fault.The deformation of surrounding rock caused by unloading in the drivage period is large and asymmetric,the roadway convergence increases with activation of the fault and secondary fracture develops in the mining period.Therefore,we proposed a specific control technique of the roadway along a fault as follows:(1) High-strength yielding bolt not only supports the shallow rock to loadbearing structures,but also releases primary deformation energy by use of a pressure release device in order to achieve high resistance to the pressure retained;(2) Grouting of near-fault ribside after initial stabilization of the rock deformation is used to reinforce the broken rock,and to improve the integral load-bearing capacity of the roadway.The research results were successfully applied to a field trial. | Yan Shuai Bai Jianbiao Li Wenfeng Chen Jigang Li Lei | 2012 | International Journal of Mining Science and Technology2012，22，4： | 11 |
| 4 | Finite element simulation and experimental test of the wear behavior for self-lubricating spherical plain bearings显示文摘In this study, based on the classical Archard adhesion wear theory, a three-dimensional finite element model was established, with the aim of simulating the failure process of self-lubricating spherical plain bearings in the swinging wear condition. The results show that the self-lubricating spherical plain bearings go through two different stages during the wear process, namely, initial wear stage and stable wear stage. Because the large contact points wear out during the initial wear stage, the maximum contact pressure decreases as the test period increases. The relatively larger wear depth region shows elliptical distribution, and the maximum distribution appears in the central contact area. The wear depth reaches 0.974 mm after swinging 25,000 times. PTFE fibers, which possess a good friction performance but poor abrasion resistance, abundantly exist on the friction surfaces of the fabric liner. Consequently, the friction torque during the initial wear stage is slightly smaller than the friction torque during the stable wear stage; however, the wear rate during the initial wear stage is high. The reliability and effectiveness of the finite element model are verified by experiment. The developed finite element model can be used for the analysis of the wear mechanisms of bearings and the prediction of the service life of bearings. | Yahong XUE Jigang CHEN Sumin GUO Qingliang MENG Junting LUO | 2018 | Friction2018，6，3： | 11 |
| 5 | Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield显示文摘Artemisia annua is the major natural source of artemisinin,an anti-malarial medicine commonly used worldwide.Here,we present chromosome-level haploid maps for two A.annua strains with different artemisinin contents to explore the relationships between genomic organization and artemisinin production.High-fidelity sequencing,optical mapping,and chromatin conformation capture sequencing were used to assemble the heterogeneous and repetitive genome and resolve the haplotypes of A.annua.Approximately 5o,ooo genes were annotated for each haplotype genome,and a triplication event that occurred approximately 58.12million years ago was examined for the first time in this species.A total of 3,903,467-5,193,414 variants(SNPs,indels,and structural variants)were identified in the 1.5-Gb genome during pairwise comparison between haplotypes,consistent with the high heterozygosity of this species.Genomic analyses revealed a correlation between artemisinin concents and the copy number of amorpha-4,11-dienes ynthasegenes.This correlation was further confirmed by resequencing of 36A.annua samples with varied artemisinin contents.Circular consensus sequencing of transcripts facilitated the detection of paralog expression.Collectively,our study provides chromosome-level allele-aware genome assemblies for two A.annua strains and new insights into the biosynthesis of artemisinin and its regulation,which will contribute to conquering malaria worldwide. | Baosheng Liao Xiaofeng Shen Li Xiang Shuai Guo Shiyu Chen Ying Meng Yu Liang Dandan Ding Junqi Bai Dong Zhang Tomasz Czechowski Yi Li Hui Yao Tingyu Mai Caroline Howard Chao Sun Haitao Liu Jiushi Liu Jin Pei Jihai Gao Jigang Wang Xiaohui Qiu Zhihai Huang Hongyi Li Ling Yuan Jianhe Wei lan Graham Jiang Xu Boli Zhang Shilin Chen | 2022 | Molecular Plant2022，15，8： | 9 |
| 6 | GPU-CA model for large-scale land-use change simulation显示文摘Land-use change simulation for large-scale regions(i.e.provincial regions or countries) is very useful for many global studies.Such simulation,however,is affected by computational capability of general computers.This paper proposes a method to implement cellular automata(CA) for land use change simulation based on graphics processing units(GPUs).This method can be applied to large-scale land-use change simulations by combining the latest GPU high-performance computing technology and CA.We carried out the experiments by simulating land-use change processes at a provincial scale.This involves a lot of sophisticated techniques,such as model mapping,and computational procedure of GPU-CA model.This proposed model has been validated by land-use change simulation in Guangdong Province,China.The comparison indicates that the GPU-CA model is faster than traditional CA by 30 times.Such improvement is crucial for land-use change simulations in provincial regions and countries.The outputs of the simulation can be further used to provide information to other global change models. | LI Dan LI Xia LIU XiaoPing CHEN YiMin LI ShaoYing LIU Kai QIAO JiGang ZHENG YiZhong ZHANG YiHan LAO ChunHua | 2012 | Chinese Science Bulletin2012，57，19： | 4 |
| 7 | Complex conforming Delaunay triangulation显示文摘A novel algorithm of conforming Delaunay triangulation for curved geometry is presented in the paper.A progress has been made for the problem puzzled Delaunay refinement where curved constraints cannot be accepted as input directly.The algorithm is based on a new sufficient condition for the existence of constraints in triangulation.It requires computing only the intersection between constraints and Voronoi edges or faces instead of the circum-sphere of curved constraint.For the termination of the algorithm when small input angles exist in constraints, a weighted method is applied to ensure that the algorithm can terminate under any input.Some two-dimensional and three-dimensional results are also presented.It is shown that the algorithm has the capability of dealing with both linear and nonlinear constraints in a consistent way, without the need of maintaining triangular meshes on face constraints. | MENG XianHai LI JiGang YANG Qin CAI Qiang CHEN QiMing | 2010 | Science China(Information Sciences)2010，53，6： | 3 |
| 8 | 18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs显示文摘Hepatic stellate cells(HSCs)are essential drivers of fibrogenesis.Inducing activated-HSC apoptosis is a promising strategy for treating hepatic fibrosis.18beta-glycyrrhetinic acid(18b-GA)is a natural compound that exists widely in herbal medicines,such as Glycyrrhiza uralensis Fisch,which is used for treating multiple liver diseases,especially in Asia.In the present study,we demonstrated that 18b-GA decreased hepatic fibrosis by inducing the apoptosis in activated HSCs.18b-GA inhibited the expression of a-smooth muscle actin and collagen type Ⅰ alpha-1.Using a chemoproteomic approach derived from activity-based protein profiling,together with cellular thermal shift assay and surface plasmon resonance,we found that 18b-GA covalently targeted peroxiredoxin 1(PRDX1)and peroxiredoxin 2(PRDX2)proteins via binding to active cysteine residues and thereby inhibited their enzymatic activities.18b-GA induced the elevation of reactive oxygen species(ROS),resulting in the apoptosis of activated HSCs.PRDX1 knockdown also led to ROS-mediated apoptosis in activated HSCs.Collectively,our findings revealed the target proteins and molecular mechanisms of 18b-GA in ameliorating hepatic fibrosis,highlighting the future development of 18b-GA as a novel therapeutic drug for hepatic fibrosis. | Qian Zhang Piao Luo Liuhai Zheng Jiayun Chen Junzhe Zhang Huan Tang Dandan Liu Xueling He Qiaoli Shi Liwei Gu Jiahao Li Qiuyan Guo Chuanbin Yang Yin Kwan Wong Fei Xia Jigang Wang | 2022 | Journal of Pharmaceutical Analysis2022，12，4： | 3 |
| 9 | Distribution of dissolved oxygen and causes of maximum concentration in the Bering Sea in July 2010显示文摘According to data obtained in the Bering Sea during the 4th Chinese National Arctic Research Expedition, the distribution of dissolved oxygen(DO) was studied, causes of its maximum concentration were discussed, and the relationships between DO and other parameters, such as salinity, temperature, and chlorophyll a were analyzed. The results showed DO concentration ranged from 0.53 to 12.05 mg/L in the Bering Sea basin. The upper waters contained high concentrations and the maximum occurred at the depth range from 20 to 50 m. The DO concentration decreased rapidly when the depth was deeper than 200 m and reached the minimum at the depth range from 500 to 1 000 m, and then increased slowly with the depth increasing but still kept at a low level. On the shelf, the DO concentration ranged from 6.53 to 16.63 mg/L with a mean value of 10.75 mg/L, and showed a characteristic of decreasing from north to south. The DO concentration was higher in the area between the Bering Sea and Lawrence Island and was lower in the southeast and southwest of Lawrence Island at the latitude of 62°N. The formation of maximum DO concentration was concerned with phytoplankton photosynthesis and formation of the themocline. To the south of Sta. B07 in the Bering Sea basin, the oxygen produced by photosynthesis permeated to the deeper water and the themocline made it difficult to exchange vertically, and to the north of Sta. B07, the maximum DO concentration occurred above the themocline due to phytoplankton activities. On the shelf, the oxygen produced by phytoplankton photosynthesis gathered at the bottom of the thermocline and formed the DO maximum concentration. In the Bering Sea basin, the DO and salinity showed a weak negative correlation(r=0.40) when the salinity was lower than 33.1, a significant negative correlation(r=0.92) when the salinity ranged from 33.1 to 33.7, and an irregular reversed parabola(r=0.95) when the salinity was greater than 33.7. | SUN Xiuwu LIN Cai CHEN Yong ZHANG Yuanbiao WANG Jigang JI Weidong | 2014 | Acta Oceanologica Sinica2014，33，6： | 2 |
| 10 | Target identification of natural medicine with chemical proteomics approach:probe synthesis,target fishing and protein identification显示文摘Natural products are an important source of new drugs for the treatment of various diseases.However,developing natural productbased new medicines through random moiety modification is a lengthy and costly process,due in part to the difficulties associated with comprehensively understanding the mechanism of action and the side effects.Identifying the protein targets of natural products is an effective strategy,but most medicines interact with multiple protein targets,which complicate this process.In recent years,an increasing number of researchers have begun to screen the target proteins of natural products with chemical proteomics approaches,which can provide a more comprehensive array of the protein targets of active small molecules in an unbiased manner.Typically,chemical proteomics experiments for target identification consist of two key steps:(1)chemical probe design and synthesis and(2)target fishing and identification.In recent decades,five different types of chemical proteomic probes and their respective target fishing methods have been developed to screen targets of molecules with different structures,and a variety of protein identification approaches have been invented.Presently,we will classify these chemical proteomics approaches,the application scopes and characteristics of the different types of chemical probes,the different protein identification methods,and the advantages and disadvantages of these strategies. | Xiao Chen Yutong Wang Nan Ma Jing Tian Yurou Shao Bo Zhu Yin Kwan Wong Zhen Liang Chang Zou Jigang Wang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 2 |
| 11 | Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy显示文摘Mitochondria as a signaling platform play crucial roles in deciding cell fate.Many classic anticancer agents are known to trigger cell death through induction of mitochondrial damage.Mitophagy,one selective autophagy,is the key mitochondrial quality control that effectively removes damaged mitochondria.However,the precise roles of mitophagy in tumorigenesis and anticancer agent treatment remain largely unclear.Here,we examined the functional implication of mitophagy in the anticancer properties of magnolol,a natural product isolated from herbal Magnolia officinalis.First,we found that magnolol induces mitochondrial depolarization,causes excessive mitochondrial fragmentation,and increases mitochondrial reactive oxygen species(mtROS).Second,magnolol induces PTEN-induced putative kinase protein 1(PINK1)-Parkin-mediated mitophagy through regulating two positive feedforward amplification loops.Third,magnolol triggers cancer cell death and inhibits neuroblastoma tumor growth via the intrinsic apoptosis pathway.Moreover,magnolol prolongs the survival time of tumor-bearing mice.Finally,inhibition of mitophagy by PINK1/Parkin knockdown or using inhibitors targeting different autophagy/mitophagy stages significantly promotes magnolol-induced cell death and enhances magnolol's anticancer efficacy,both in vitro and in vivo.Altogether,our study demonstrates that magnolol can induce autophagy/mitophagy and apoptosis,whereas blockage of autophagy/mitophagy remarkably enhances the anticancer efficacy of magnolol,suggesting that targeting mitophagy may be a promising strategy to overcome chemoresistance and improve anticancer therapy. | Yancheng Tang Liming Wang Tao Yi Jun Xu Jigang Wang Jiang-Jiang Qin Qilei Chen Ka-Man Yip Yihang Pan Peng Hong Yingying Lu Han-Ming Shen Hu-Biao Chen | 2021 | Acta Pharmaceutica Sinica B2021，11，12： | 2 |
| 12 | Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity显示文摘Triple-negative breast cancer(TNBC)is the most challenging subtype of breast cancer.Various endeavor has been made to explore the molecular biology basis of TNBC.Herein,we reported a novel function of factor Kinectin 1(KTN1)as a carcinogenic promoter in TNBC.KTN1 expression in TNBC was increased compared with adjacent tissues or luminal or Her2 subtypes of breast cancer,and TNBC patients with high KTN1 expression have poor prognosis.In functional studies,knockdown of KTN1 inhibited the proliferation and invasiveness of TNBC both in vitro and in vivo,while overexpression of KTN1 promoted cancer cell proliferation and invasiveness.RNA-seq analysis revealed that the interaction of cytokine-cytokine receptor,particularly CXCL8 gene,was upregulated by KTN1,which was supported by the further experiments.CXCL8 depletion inhibited the tumorigenesis and progression of TNBC.Additionally,rescue experiments validated that KTN1-mediated cell growth acceleration in TNBC was dependent on CXCL8 both in vitro and in vivo.Furthermore,it was found that KTN1 enhanced the phosphorylation of NF-κB/p65 protein at Ser536 site,and specifically bound to NF-κB/p65 protein in the nucleus and cytoplasm of cells.Moreover,the transcription of CXCL8 gene was directly upregulated by the complex of KTN1 and NF-κB/p65 protein.Taken together,our results elucidated a novel mechanism of KTN1 gene in TNBC tumorigenesis and progression.KTN1 may be a potential molecular target for the development of TNBC treatment. | Lin Gao Shanze Chen Malin Hong Wenbin Zhou Bilan Wang Junying Qiu Jinquan Xia Pan Zhao Li Fu Jigang Wang Yong Dai Ni Xie Qinhe Yang Hsien-Da Huang Xiang Gao Chang Zou | 2021 | Signal Transduction and Targeted Therapy2021，6，8： | 2 |
| 13 | Lower Bounds and a Nearly Fastest General Parallel Branch-and-Bound Algorithm显示文摘In this paper, it is supposed that the B&B algorithm finds the first optimal solution after h nodes have been expanded and m active nodes have been created in the state-space tree. Then the lower bound Ω(m + hlog h) of the running time for the general sequential B&B algorithm and the lower bound Ω(m/p+ hlogp) for the general parallel best-first B&B algorithm in PRAMCREW are proposed, where p is the number of processors available. Moreover, the lower bound Ω(M/p+H+ (H/P) log (H/P)) is presented for the parallel algorithms on distributed memory system, where M and H represent total number of the active nodes and that of the expanded nodes processed by p processors, respectively. In addition, a nearly fastest general parallel best-first B&B algorithm is put forward. The parallel algorithm is the fastest one as p = max{hε,γ}, where ε= 1/──logh, and r is the largest branch number of the nodes in the state-space tree. | Wu, Jigang Xie, Xing Wan, Yingyu Chen, Guoliang | 2000 | Journal of Systems Engineering and Electronics2000，11，3： | 2 |
| 14 | Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis显示文摘Sepsis is characterized by a severe and life-threatening host immune response to polymicrobial infection accompanied by organ dysfunction.Studies on the therapeutic effect and mechanism of immunomodulatory drugs on the sepsis-induced hyperinflammatory or immunosuppression states of various immune cells remain limited.This study aimed to investigate the protective effects and underlying mechanism of artesunate(ART)on the splenic microenvironment of cecal ligation and puncture-induced sepsis model mice using single-cell RNA sequencing(scRNA-seq)and experimental validations.The scRNA-seq analysis revealed that ART inhibited the activation of pro-inflammatory macrophages recruited during sepsis.ART could restore neutrophils’chemotaxis and immune function in the septic spleen.It inhibited the activation of T regulatory cells but promoted the cytotoxic function of natural killer cells during sepsis.ART also promoted the differentiation and activity of splenic B cells in mice with sepsis.These results indicated that ART could alleviate the inflammatory and/or immunosuppressive states of various immune cells involved in sepsis to balance the immune homeostasis within the host.Overall,this study provided a comprehensive investigation of the regulatory effect of ART on the splenic microenvironment in sepsis,thus contributing to the application of ART as adjunctive therapy for the clinical treatment of sepsis. | Jiayun Chen Xueling He Yunmeng Bai Jing Liu Yin Kwan Wong Lulin Xie Qian Zhang Piao Luo Peng Gao Liwei Gu Qiuyan Guo Guangqing Cheng Chen Wang Jigang Wang | 2023 | Journal of Pharmaceutical Analysis2023，13，7： | 1 |
| 15 | Estrogen and pure antiestrogen fulvestrant (ICI 182 780) augment cell–matrigel adhesion of MCF-7 breast cancer cells through a novel G protein coupled estrogen receptor (GPR30)-to-calpain signaling axis显示文摘 | Yan Chen Zheng Li Yan He Dandan Shang Jigang Pan Hongmei Wang Huamei Chen Zhuxia Zhu Lei Wan Xudong Wang | 2014 | Toxicology and Applied Pharmacology2014，，： | 1 |
| 16 | Differential DNA methylation profiles of human B lymphocytes and Epstein-Barr virus-immortalized B lymphocytes显示文摘Objective: This study aimed to comprehensively assess Epstein-Barr virus(EBV)-induced methylation alterations of B cell across whole genome.Methods: We compared DNA methylation patterns of primary B cells and corresponding lymphoblastoid cell lines(LCLs) from eight participants. The genome-wide DNA methylation profiles were compared at over 850,000 genome-wide methylation sites.Results: DNA methylation analysis revealed 87,732 differentially methylated Cp G sites, representing approximately 12.41% of all sites in LCLs compared to primary B cells. The hypermethylated and hypomethylated Cp G sites were about 22.75% or 77.25%, respectively. Only 0.8% of hypomethylated sites and 4.5% of hypermethylated sites were located in Cp G islands, whereas 8.0% of hypomethylated sites and 16.3% of hypermethylated sites were located in shore(N_shore and S_shore). Using principal component analysis of the DNA methylation profiles, primary B cells and LCLs could be accurately predicted. Gene Ontology(GO) and Kyoto Encyclopedia of Genes and Genomes(KEGG) analysis of differently methylated genes revealed that most of the top GO biological processes were related to cell activation and immune response, and some top enrichment pathways were related with activation and malignant transformation of human B cells.Conclusions: Our study demonstrated genome-wide DNA methylation variations between primary B cells and corresponding LCLs, which might yield new insight on the methylation mechanism of EBV-induced immortalization. | Chaoting Zhang Rui Zhang Zhiqiang Chen Jing Chen Jigang Ruan Zheming Lu Hongchao Xiong Wenjun Yang | 2018 | Chinese Journal of Cancer Research2018，30，1： | 1 |
| 17 | Chemical proteomic profling with photoaffinity labeling strategy identifies antimalarial targets of artemisinin显示文摘Present research on the antimalarial mechanisms of artemisinin(ART)is mainly focused on covalent drug binding targets alkylated by free radicals,while non-covalent binding targets have rarely been reported.Here,we developed a novel photoaffinity probe of ART to globally capture and identify the antimalarial target proteins of ART through chemical proteomics.The results demonstrated that ART can bind to par-asite proteins by both covalent and non-covalent modification,and these may jointly contribute to the antimalarial effects.Our work enriches the research on the antimalarial targets of ART,and provides a new perspective for further exploring the antimalarial mechanism of ART. | Peng Gao Jiayun Chen Peng Sun Jianyou Wang Huan Tang Fei Xia Liwei Gu Huimin Zhang Chen Wang Yin Kwan Wong Yinhua Zhu Chengchao Xu Jigang Wang | 2023 | Chinese Chemical Letters2023，34，12： | 1 |
| 18 | The intelligenl control design and realization of an AC contaclnr with wide-range input voltage显示文摘 | Zhiying Chen Lian Chcn Jigang Yu | 2011 | Electric Power Equipment-Switching Technology2011，，1： | 1 |
| 19 | Industrial practice of clad-rolling in heavy steel plate production显示文摘In this paper,a brief introduction on clad-rolling heavy steel plates of 90 mm and 140 mm thick is presented.The steel plates were hot rolled by 265mm slabs that are cladded by double 135mm continuous casting slabs of Q235 steel.After hot rolling,interface of the cladding slabs completely disappeared, revealing uniform grains similar to the rest of the materials.Ultrasonic tests were carried out on both steel plates,demonstrating excellent results.Through thickness tensile tests were also implemented on both steel plates,resulting in perfect mechanical properties complying with specific standards.The result proves that a minimum reduction rate of 1.89 is available in producing 140 mm thick steel plate with excellent through thickness properties. | SUN Weihua~(1)),MA Xingyun~(1)),ZHAO Qian~(1)),MENG Chunguang~(1)), CHEN Qixiang~(1)),LUO Zongan~(2)) and WANG Guodong~(2)) 1) Technology Centre,Jigang Group Co.,Ltd.,Jinan 250101,Shandong,China 2) RAL,North Eastern University,Shenyang 110006,Liaoning,China | 2010 | Baosteel Technical Research2010，4，S1： | 1 |
| 20 | 显示文摘 | Guofang Lin Qingwen Ma Jigang Chen Jianhua Shen Cuiqing Xiang Klaus Golka Dongsheng Zhang | 2001 | Archives of Toxicology2001，，9： | 1 |
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