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| 1 | Management and outcome of pelvic fractures in elderly patients: a retrospective study of 40 cases显示文摘 | Dong Jinlei Hao Wei Wang Bomin Wang Lubo Li Lianxin Mu Weidong Yang Yongliang Xin Maoyuan Wang Fu Zhou Dongsheng | 2014 | Chinese Medical Journal2014,,15: | 8 |
| 2 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022,11,2: | 4 |
| 3 | Gankyrin promotes tumor growth and metastasis through activation of IL‐6/STAT3 signaling in human cholangiocarcinoma显示文摘 | Tongsen Zheng Xuehui Hong Jiabei Wang Tiemin Pei Yingjian Liang Dalong Yin Ruipeng Song Xuan Song Zhaoyang Lu Shuyi Qi Jiaren Liu Boshi Sun Changming Xie Shangha Pan Yuejin Li Xiaohe Luo Shuai Li Xiang Fang Nishant Bhatta Hongchi Jiang Lianxin Liu | 2014 | Hepatology2014,,: | 2 |
| 4 | An ensemble estimation of impact times and strength of Fukushima nuclear pollution to the east coast of China and the west coast of America显示文摘Based on the statistics of all surface drifting buoys of 1978-2011 and Lagrangian tracers simulated from high quality ocean reanalysis currents,the impact times and strength of Fukushima nuclear pollution to the east coast of China and the west coast of America have been estimated.Under the circumstances of the radioactive pollutants drifting in the ocean surface,preliminary research results show that while the tracers took about 4 years to reach the west coast of USA,there are two types of tracers to carry out Fukushima nuclear pollutants to reach the east coast of China,corresponding to 1.5-year recirculation gyre transport and 3.5-year subtropical circulation transport.The distributions of the impact strength at these time scales are given according to the variation of relative number concentration with time combined with the decaying rate of radioactive matter.For example,starting from 1% at 1.5-year,of the initial level at the originating area of Fukushima nuclear pollution,the impact strength of Cesium-137 in the South China Sea continuously increases up to 3% by 4 years,while the impact strength of Cesium-137 in the west coast of America is as high as 4% due to the role of strong Kuroshio-extension currents as a major transport mechanism of nuclear pollutants for that area. | HAN GuiJun LI Wei FU HongLi ZHANG XueFeng WANG XiDong WU XinRong ZHANG LianXin | 2013 | Science China Earth Sciences2013,56,8: | 2 |
| 5 | A variational successive corrections approach for the sea ice concentration analysis显示文摘The sea ice concentration observation from satellite remote sensing includes the spatial multi-scale information.However,traditional data assimilation methods cannot better extract the valuable information due to the complicated variability of the sea ice concentration in the marginal ice zone.A successive corrections analysis using variational optimization method,called spatial multi-scale recursive filter(SMRF),has been designed in this paper to extract multi-scale information resolved by sea ice observations.It is a combination of successive correction methods(SCM)and minimization algorithms,in which various observational scales,from longer to shorter wavelengths,can be extracted successively.As a variational objective analysis scheme,it gains the advantage over the conventional approaches that analyze all scales resolved by observations at one time,and also,the specification of parameters is more convenient.Results of single-observation experiment demonstrate that the SMRF scheme possesses a good ability in propagating observational signals.Further,it shows a superior performance in extracting multi-scale information in a two-dimensional sea ice concentration(SIC)experiment with the real observations from Special Sensor Microwave/Imager SIC(SSMI). | Xuefeng Zhang Lu Yang Hongli Fu Dong Li Zheqi Shen Lianxin Zhang Xuhui Hu | 2020 | Acta Oceanologica Sinica2020,39,9: | 1 |
| 6 | The effect of (Li,Ce) and (K,Ce) doping in Aurivillius phase material CaBi 4 Ti 4 O 15显示文摘 | Haixue Yan Zhen Zhang Weimin Zhu Lianxin He Youhua Yu Chengen Li Jiaguang Zhou | 2004 | Materials Research Bulletin2004,,9: | 1 |
| 7 | Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a highly infectious respiratory disease that continues to pose a serious global public health emergency.The disease shows a high infection rate,long incubation period,and rapidly emerging variants,which have led to its rapid spread worldwide(Krammer 2020).Many vaccines have been developed for the control of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the virus responsible for COVID-19,including vaccines based on messenger RNA(mRNA)(Polack et al.2020),viral vectors(Zhu et al.2020),recombinant proteins(Yang et al.2020),and inactivated SARS-CoV-2(Zhang et al.2021). | Dali Tong Mei Zhang Yunru Yang Han Xia Haiyang Tong Huajun Zhang Weihong Zeng Muziying Liu Yan Wu Huan Ma Xue Hu Weiyong Liu Yuan Cai Yanfeng Yao Yichuan Yao Kunpeng Liu Shifang Shan Yajuan Li Ge Gao Weiwei Guo Yun Peng Shaohong Chen Juhong Rao Jiaxuan Zhao Juan Min Qingjun Zhu Yanmin Zheng Lianxin Liu Chao Shan Kai Zhong Zilong Qiu Tengchuan Jin Sandra Chiu Zhiming Yuan Tian Xue | 2023 | Protein & Cell2023,14,1: | 0 |
| 8 | A Study of Transport and Impact Strength of Fukushima Nuclear Pollutants in the North Pacific Surface显示文摘Based on the statistics of surface drifter data of 1979–2011 and the simulation of nuclear pollutant particulate movements simulated using high quality ocean reanalysis surface current dataset, the transport pathways and impact strength of Fukushima nuclear pollutants in the North Pacific have been estimated. The particulates are used to increase the sampling size and enhance the representativeness of statistical results. The trajectories of the drifters and particulates are first examined to identify typical drifting pathways. The results show that there are three types of transport paths for nuclear pollutants at the surface: 1) most pollutant particles move eastward and are carried by the Kuroshio and Kuroshio-extension currents and reach the east side of the North Pacific after about 3.2–3.9 years; 2) some particles travel with the subtropical circulation branch and reach the east coast of China after about 1.6 years according to one drifter trajectory and about 3.6 years according to particulate trajectories; 3) a little of them travel with local, small scale circulations and reach the east coast of China after about 1.3–1.8 years. Based on the particulates, the impact strength of nuclear pollutants at these time scales can be estimated according to the temporal variations of relative concentration combined with the radioactive decay rate. For example, Cesium-137, carried by the strong North Pacific current, mainly accumulates in the eastern North Pacific and its impact strength is 4% of the initial level at the originating Fukushima area after 4 years. Due to local eddies, Cesium-137 in the western North Pacific is 1% of the initial pollutant level after 1.5 years and continuously increases to 3% after 4 years. The vertical movement of radioactive pollutants is not taken into account in the present study, and the estimation accuracy would be improved by considering three-dimensional flows. | FU Hongli LI Wei ZHANG Xuefeng HAN Guijun WANG Xidong WU Xinrong ZHANG Lianxin | 2014 | Journal of Ocean University of China2014,13,2: | 0 |